TreeWAS – Variant ID: rs1655906

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	0.000	0.003	0.997
L40 Psoriasis	0.000	0.008	0.992
G35 Multiple sclerosis	0.992	0.008	0.000
L40.5 Arthropathic psoriasis	0.000	0.009	0.991
E83 Disorders of mineral metabolism	0.976	0.024	0.000
E70-E90 Metabolic disorders	0.974	0.026	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.973	0.027	0.000
E89.0 Postprocedural hypothyroidism	0.971	0.029	0.000
E03.9 Hypothyroidism, unspecified	0.965	0.035	0.000
E03 Other hypothyroidism	0.954	0.046	0.000
E00-E07 Disorders of thyroid gland	0.950	0.050	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.946	0.054	0.000
E89.2 Postprocedural hypoparathyroidism	0.891	0.109	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.875	0.125	0.000
E73 Lactose intolerance	0.812	0.188	0.000
E06 Thyroiditis	0.799	0.201	0.000
E89.4 Postprocedural ovarian failure	0.797	0.203	0.000
L40.0 Psoriasis vulgaris	0.000	0.215	0.785
E84 Cystic fibrosis	0.770	0.229	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.753	0.247	0.000
E74 Other disorders of carbohydrate metabolism	0.749	0.251	0.000
E80.1 Porphyria cutanea tarda	0.743	0.257	0.000
E04 Other non-toxic goitre	0.734	0.266	0.000
E40-E46 Malnutrition	0.728	0.272	0.000
E65-E68 Obesity and other hyperalimentation	0.727	0.273	0.000
L40.8 Other psoriasis	0.000	0.275	0.725
E06.3 Autoimmune thyroiditis	0.717	0.283	0.000
L40.4 Guttate psoriasis	0.000	0.288	0.711
L40.3 Pustulosis palmaris et plantaris	0.000	0.288	0.711
L40.2 Acrodermatitis continua	0.000	0.288	0.711
L40.1 Generalised pustular psoriasis	0.000	0.288	0.711
E80.4 Gilbert's syndrome	0.706	0.294	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.700	0.300	0.000
E83.8 Other disorders of mineral metabolism	0.700	0.300	0.000
E83.2 Disorders of zinc metabolism	0.700	0.300	0.000
E83.0 Disorders of copper metabolism	0.700	0.300	0.000
E04.2 Non-toxic multinodular goitre	0.699	0.301	0.000
E79 Disorders of purine and pyrimidine metabolism	0.698	0.302	0.000
E77 Disorders of glycoprotein metabolism	0.698	0.302	0.000
E76 Disorders of glycosaminoglycan metabolism	0.698	0.302	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.698	0.302	0.000
E72 Other disorders of amino-acid metabolism	0.698	0.302	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.698	0.302	0.000
E70 Disorders of aromatic amino-acid metabolism	0.698	0.302	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.698	0.302	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.698	0.302	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.698	0.302	0.000
E89.5 Postprocedural testicular hypofunction	0.698	0.302	0.000
E89.1 Postprocedural hypoinsulinaemia	0.698	0.302	0.000
E73.9 Lactose intolerance, unspecified	0.696	0.304	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.695	0.305	0.000
E03.5 Myxoedema coma	0.684	0.316	0.000
E03.4 Atrophy of thyroid (acquired)	0.684	0.316	0.000
E03.3 Postinfectious hypothyroidism	0.684	0.316	0.000
E03.1 Congenital hypothyroidism without goitre	0.684	0.316	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.684	0.316	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.681	0.319	0.000
E00 Congenital iodine-deficiency syndrome	0.681	0.319	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.681	0.319	0.000
E80.6 Other disorders of bilirubin metabolism	0.664	0.336	0.000
E65 Localised adiposity	0.654	0.346	0.000
E80.2 Other porphyria	0.649	0.351	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.630	0.370	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.628	0.372	0.000
E80.5 Crigler-Najjar syndrome	0.628	0.372	0.000
E80.3 Defects of catalase and peroxydase	0.628	0.372	0.000
E80.0 Hereditary erythropoietic porphyria	0.628	0.372	0.000
E84.9 Cystic fibrosis, unspecified	0.625	0.375	0.000
E83.3 Disorders of phosphorus metabolism	0.614	0.385	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.606	0.394	0.000
E05.9 Thyrotoxicosis, unspecified	0.601	0.399	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.588	0.412	0.000
E50-E64 Other nutritional deficiencies	0.583	0.417	0.000
E73.8 Other lactose intolerance	0.582	0.418	0.000
E73.1 Secondary lactase deficiency	0.582	0.418	0.000
E73.0 Congenital lactase deficiency	0.582	0.418	0.000
E06.5 Other chronic thyroiditis	0.573	0.427	0.000
E06.4 Drug-induced thyroiditis	0.573	0.427	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.573	0.427	0.000
E06.1 Subacute thyroiditis	0.573	0.427	0.000
E06.0 Acute thyroiditis	0.573	0.427	0.000
E46 Unspecified protein-energy malnutrition	0.572	0.428	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.564	0.436	0.000
E84.8 Cystic fibrosis with other manifestations	0.552	0.447	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.552	0.447	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.552	0.447	0.000
E88 Other metabolic disorders	0.551	0.448	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.537	0.463	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.537	0.463	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.537	0.463	0.000
E74.2 Disorders of galactose metabolism	0.537	0.463	0.000
E74.1 Disorders of fructose metabolism	0.537	0.463	0.000
E74.0 Glycogen storage disease	0.537	0.463	0.000
E03.8 Other specified hypothyroidism	0.535	0.465	0.000
E07 Other disorders of thyroid	0.535	0.465	0.000
E04.8 Other specified non-toxic goitre	0.526	0.474	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.522	0.478	0.000
E45 Retarded development following protein-energy malnutrition	0.522	0.478	0.000
E43 Unspecified severe protein-energy malnutrition	0.522	0.478	0.000
E42 Marasmic kwashiorkor	0.522	0.478	0.000
E41 Nutritional marasmus	0.522	0.478	0.000
E40 Kwashiorkor	0.522	0.478	0.000
E67 Other hyperalimentation	0.521	0.478	0.000
E68 Sequelae of hyperalimentation	0.521	0.478	0.000
E04.0 Non-toxic diffuse goitre	0.521	0.478	0.000
E06.9 Thyroiditis, unspecified	0.501	0.499	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.501	0.499	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.501	0.499	0.000
E70.3 Albinism	0.501	0.499	0.000
E70.2 Disorders of tyrosine metabolism	0.501	0.499	0.000
E70.1 Other hyperphenylalaninaemias	0.501	0.499	0.000
E70.0 Classical phenylketonuria	0.501	0.499	0.000
E71.3 Disorders of fatty-acid metabolism	0.501	0.499	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.501	0.499	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.501	0.499	0.000
E71.0 Maple-syrup-urine disease	0.501	0.499	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.501	0.499	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.501	0.499	0.000
E72.5 Disorders of glycine metabolism	0.501	0.499	0.000
E72.4 Disorders of ornithine metabolism	0.501	0.499	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.501	0.499	0.000
E72.2 Disorders of urea cycle metabolism	0.501	0.499	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.501	0.499	0.000
E72.0 Disorders of amino-acid transport	0.501	0.499	0.000
E75.6 Lipid storage disorder, unspecified	0.501	0.499	0.000
E75.5 Other lipid storage disorders	0.501	0.499	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.501	0.499	0.000
E75.3 Sphingolipidosis, unspecified	0.501	0.499	0.000
E75.2 Other sphingolipidosis	0.501	0.499	0.000
E75.1 Other gangliosidosis	0.501	0.499	0.000
E75.0 GM2 gangliosidosis	0.501	0.499	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.501	0.499	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.501	0.499	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.501	0.499	0.000
E76.2 Other mucopolysaccharidoses	0.501	0.499	0.000
E76.1 Mucopolysaccharidosis, type II	0.501	0.499	0.000
E76.0 Mucopolysaccharidosis, type I	0.501	0.499	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.501	0.499	0.000
E77.8 Other disorders of glycoprotein metabolism	0.501	0.499	0.000
E77.1 Defects in glycoprotein degradation	0.501	0.499	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.501	0.499	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.501	0.499	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.501	0.499	0.000
E79.1 Lesch-Nyhan syndrome	0.501	0.499	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.501	0.499	0.000
E05.5 Thyroid crisis or storm	0.498	0.501	0.000
E05.4 Thyrotoxicosis factitia	0.498	0.501	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.498	0.501	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.498	0.501	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.488	0.511	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.488	0.511	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.488	0.511	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.488	0.511	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.488	0.511	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.488	0.511	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.488	0.511	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.488	0.511	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.488	0.512	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.482	0.517	0.000
E53 Deficiency of other B group vitamins	0.482	0.518	0.000
I83 Varicose veins of lower extremities	0.465	0.535	0.000
E83.5 Disorders of calcium metabolism	0.465	0.535	0.000
E85 Amyloidosis	0.464	0.535	0.000
E05.8 Other thyrotoxicosis	0.459	0.541	0.000
E58 Dietary calcium deficiency	0.439	0.561	0.000
G36 Other acute disseminated demyelination	0.435	0.565	0.000
L40-L45 Papulosquamous disorders	0.268	0.566	0.166
G37 Other demyelinating diseases of central nervous system	0.424	0.576	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.419	0.580	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.418	0.582	0.000
E63 Other nutritional deficiencies	0.418	0.582	0.000
E56 Other vitamin deficiencies	0.418	0.582	0.000
E51 Thiamine deficiency	0.418	0.582	0.000
E50 Vitamin A deficiency	0.418	0.582	0.000
E60 Dietary zinc deficiency	0.418	0.582	0.000
E59 Dietary selenium deficiency	0.418	0.582	0.000
E54 Ascorbic acid deficiency	0.418	0.582	0.000
E52 Niacin deficiency [pellagra]	0.418	0.582	0.000
E53.8 Deficiency of other specified B group vitamins	0.407	0.593	0.000
E04.9 Non-toxic goitre, unspecified	0.403	0.597	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.401	0.599	0.000
E88.9 Metabolic disorder, unspecified	0.395	0.604	0.000
E88.8 Other specified metabolic disorders	0.395	0.604	0.000
E88.3 Tumour lysis syndrome	0.395	0.604	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.392	0.608	0.000
E89.3 Postprocedural hypopituitarism	0.390	0.609	0.001
E07.1 Dyshormogenetic goitre	0.384	0.616	0.000
E07.0 Hypersecretion of calcitonin	0.384	0.616	0.000
E44.1 Mild protein-energy malnutrition	0.374	0.625	0.000
E44.0 Moderate protein-energy malnutrition	0.374	0.625	0.000
E67.8 Other specified hyperalimentation	0.374	0.626	0.000
E67.3 Hypervitaminosis D	0.374	0.626	0.000
E67.2 Megavitamin-B6 syndrome	0.374	0.626	0.000
E67.1 Hypercarotenaemia	0.374	0.626	0.000
E67.0 Hypervitaminosis A	0.374	0.626	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.369	0.631	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.363	0.637	0.000
E07.8 Other specified disorders of thyroid	0.352	0.648	0.000
E53.9 Vitamin B deficiency, unspecified	0.350	0.650	0.000
Chapter IX Diseases of the circulatory system	0.347	0.653	0.000
E15 Nondiabetic hypoglycaemic coma	0.346	0.654	0.000
Chapter VI Diseases of the nervous system	0.346	0.654	0.000
E53.1 Pyridoxine deficiency	0.345	0.654	0.000
E53.0 Riboflavin deficiency	0.345	0.654	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.346	0.654	0.000
# Top node	0.345	0.655	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.343	0.657	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.339	0.661	0.000
I71 Aortic aneurysm and dissection	0.338	0.662	0.000
L20-L30 Dermatitis and eczema	0.335	0.665	0.000
E85.8 Other amyloidosis	0.333	0.667	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.333	0.667	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.333	0.667	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.333	0.667	0.000
L60-L75 Disorders of skin appendages	0.333	0.667	0.000
Chapter V Mental and behavioural disorders	0.332	0.668	0.000
E88.2 Lipomatosis, not elsewhere classified	0.330	0.669	0.000
L29 Pruritus	0.325	0.675	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.323	0.677	0.000
I72 Other aneurysm	0.322	0.678	0.000
E85.3 Secondary systemic amyloidosis	0.322	0.678	0.000
L71 Rosacea	0.321	0.679	0.000
F60-F69 Disorders of adult personality and behaviour	0.320	0.680	0.000
I85 Oesophageal varices	0.318	0.682	0.000
L03.1 Cellulitis of other parts of limb	0.317	0.683	0.000
L73 Other follicular disorders	0.315	0.685	0.000
I70 Atherosclerosis	0.313	0.687	0.000
G36.9 Acute disseminated demyelination, unspecified	0.312	0.688	0.000
G36.8 Other specified acute disseminated demyelination	0.312	0.688	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.312	0.688	0.000
G36.0 Neuromyelitis optica [Devic]	0.312	0.688	0.000
L44 Other papulosquamous disorders	0.192	0.689	0.119
L41 Parapsoriasis	0.192	0.689	0.119
L45 Papulosquamous disorders in diseases classified elsewhere	0.192	0.689	0.119
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.311	0.689	0.000
L42 Pityriasis rosea	0.214	0.691	0.096
Q20-Q28 Congenital malformations of the circulatory system	0.307	0.693	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.306	0.694	0.000
L43 Lichen planus	0.228	0.695	0.076
L03 Cellulitis	0.304	0.696	0.000
G37.5 Concentric sclerosis [Balo]	0.304	0.696	0.000
G37.4 Subacute necrotising myelitis	0.304	0.696	0.000
G37.2 Central pontine myelinolysis	0.304	0.696	0.000
G37.1 Central demyelination of corpus callosum	0.304	0.696	0.000
G37.0 Diffuse sclerosis	0.304	0.696	0.000
E61 Deficiency of other nutrient elements	0.302	0.697	0.001
I88 Nonspecific lymphadenitis	0.301	0.699	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.300	0.699	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.300	0.700	0.000
E50.9 Vitamin A deficiency, unspecified	0.300	0.700	0.000
E50.8 Other manifestations of vitamin A deficiency	0.300	0.700	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.300	0.700	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.300	0.700	0.000
E50.5 Vitamin A deficiency with night blindness	0.300	0.700	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.300	0.700	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.300	0.700	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.300	0.700	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.300	0.700	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.300	0.700	0.000
E51.9 Thiamine deficiency, unspecified	0.300	0.700	0.000
E51.8 Other manifestations of thiamine deficiency	0.300	0.700	0.000
E51.2 Wernicke's encephalopathy	0.300	0.700	0.000
E51.1 Beriberi	0.300	0.700	0.000
E56.9 Vitamin deficiency, unspecified	0.300	0.700	0.000
E56.8 Deficiency of other vitamins	0.300	0.700	0.000
E56.1 Deficiency of vitamin K	0.300	0.700	0.000
E56.0 Deficiency of vitamin E	0.300	0.700	0.000
E63.9 Nutritional deficiency, unspecified	0.300	0.700	0.000
E63.8 Other specified nutritional deficiencies	0.300	0.700	0.000
E63.1 Imbalance of constituents of food intake	0.300	0.700	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.300	0.700	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.300	0.700	0.000
E64.8 Sequelae of other nutritional deficiencies	0.300	0.700	0.000
E64.3 Sequelae of rickets	0.300	0.700	0.000
E64.2 Sequelae of vitamin C deficiency	0.300	0.700	0.000
E64.1 Sequelae of vitamin A deficiency	0.300	0.700	0.000
E64.0 Sequelae of protein-energy malnutrition	0.300	0.700	0.000
L73.2 Hidradenitis suppurativa	0.300	0.700	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.299	0.701	0.000
E55 Vitamin D deficiency	0.298	0.701	0.000
L71.9 Rosacea, unspecified	0.298	0.702	0.000
Chapter XXII Codes for special purposes	0.298	0.702	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.297	0.703	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.297	0.703	0.000
I60-I69 Cerebrovascular diseases	0.297	0.703	0.000
F60 Specific personality disorders	0.296	0.704	0.000
Chapter XX External causes of morbidity and mortality	0.295	0.705	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.293	0.707	0.000
I72.3 Aneurysm of iliac artery	0.292	0.708	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.290	0.710	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.289	0.711	0.000
E07.9 Disorder of thyroid, unspecified	0.289	0.711	0.000
L21 Seborrhoeic dermatitis	0.287	0.713	0.000
E66 Obesity	0.287	0.713	0.000
G30-G32 Other degenerative diseases of the nervous system	0.287	0.713	0.000
L73.8 Other specified follicular disorders	0.285	0.715	0.000
L29.8 Other pruritus	0.283	0.717	0.000
I87 Other disorders of veins	0.281	0.719	0.000
I69 Sequelae of cerebrovascular disease	0.280	0.720	0.000
L63 Alopecia areata	0.279	0.721	0.000
F69 Unspecified disorder of adult personality and behaviour	0.279	0.721	0.000
F80-F89 Disorders of psychological development	0.279	0.721	0.000
L29.9 Pruritus, unspecified	0.278	0.722	0.000
I85.9 Oesophageal varices without bleeding	0.277	0.723	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.275	0.725	0.000
Q23 Congenital malformations of aortic and mitral valves	0.273	0.727	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.273	0.727	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.272	0.728	0.000
L29.0 Pruritus ani	0.272	0.728	0.000
V40-V49 Car occupant injured in transport accident	0.270	0.730	0.000
L29.2 Pruritus vulvae	0.270	0.730	0.000
F10.1 Harmful use	0.269	0.731	0.000
L04 Acute lymphadenitis	0.269	0.731	0.000
L71.8 Other rosacea	0.269	0.731	0.000
E85.9 Amyloidosis, unspecified	0.267	0.732	0.001
I72.4 Aneurysm of artery of lower extremity	0.268	0.732	0.000
Q25 Congenital malformations of great arteries	0.268	0.732	0.000
L20 Atopic dermatitis	0.267	0.733	0.000
Q24 Other congenital malformations of heart	0.265	0.735	0.000
G20-G26 Extrapyramidal and movement disorders	0.264	0.736	0.000
I74 Arterial embolism and thrombosis	0.264	0.736	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.263	0.737	0.000
L71.1 Rhinophyma	0.263	0.737	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.262	0.738	0.000
L28 Lichen simplex chronicus and prurigo	0.260	0.740	0.000
I65.2 Occlusion and stenosis of carotid artery	0.259	0.741	0.000
I72.8 Aneurysm of other specified arteries	0.259	0.741	0.000
F60.9 Personality disorder, unspecified	0.256	0.744	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.255	0.745	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.254	0.746	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.254	0.746	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.253	0.747	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.253	0.747	0.000
F50 Eating disorders	0.252	0.748	0.000
F10.5 Psychotic disorder	0.252	0.748	0.000
F11 Mental and behavioural disorders due to use of opioids	0.252	0.748	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.252	0.748	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.251	0.749	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.250	0.749	0.000
Q23.1 Congenital insufficiency of aortic valve	0.250	0.750	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.249	0.751	0.000
I00-I02 Acute rheumatic fever	0.249	0.751	0.000
F60.7 Dependent personality disorder	0.249	0.751	0.000
I85.0 Oesophageal varices with bleeding	0.248	0.752	0.000
Q21 Congenital malformations of cardiac septa	0.248	0.752	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.248	0.752	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.247	0.753	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.247	0.753	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.247	0.753	0.000
Q80-Q89 Other congenital malformations	0.246	0.753	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.246	0.754	0.000
F64 Gender identity disorders	0.245	0.755	0.000
V20-V29 Motorcycle rider injured in transport accident	0.245	0.755	0.000
F55 Abuse of non-dependence-producing substances	0.244	0.756	0.000
V10-V19 Pedal cyclist injured in transport accident	0.243	0.757	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.243	0.757	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.243	0.757	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.243	0.757	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.243	0.757	0.000
L68 Hypertrichosis	0.243	0.757	0.000
L66 Cicatricial alopecia [scarring hair loss]	0.242	0.757	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.242	0.758	0.000
G30 Alzheimer's disease	0.241	0.759	0.000
L63.9 Alopecia areata, unspecified	0.241	0.759	0.000
E85.4 Organ-limited amyloidosis	0.240	0.759	0.001
E83.4 Disorders of magnesium metabolism	0.240	0.759	0.001
G25 Other extrapyramidal and movement disorders	0.240	0.760	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.240	0.760	0.000
Q24.8 Other specified congenital malformations of heart	0.240	0.760	0.000
L24 Irritant contact dermatitis	0.240	0.760	0.000
L26 Exfoliative dermatitis	0.240	0.760	0.000
L22 Diaper [napkin] dermatitis	0.240	0.760	0.000
L23 Allergic contact dermatitis	0.240	0.760	0.000
I69.3 Sequelae of cerebral infarction	0.239	0.761	0.000
Q28 Other congenital malformations of circulatory system	0.239	0.761	0.000
L75 Apocrine sweat disorders	0.239	0.761	0.000
L74 Eccrine sweat disorders	0.239	0.761	0.000
L67 Hair colour and hair shaft abnormalities	0.239	0.761	0.000
L64 Androgenic alopecia	0.239	0.761	0.000
L62 Nail disorders in diseases classified elsewhere	0.239	0.761	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.239	0.761	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.239	0.761	0.000
Y44 Agents primarily affecting blood constituents	0.238	0.762	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.238	0.762	0.000
F80 Specific developmental disorders of speech and language	0.238	0.762	0.000
I77 Other disorders of arteries and arterioles	0.238	0.762	0.000
I05-I09 Chronic rheumatic heart diseases	0.237	0.763	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.236	0.764	0.000
I65.1 Occlusion and stenosis of basilar artery	0.235	0.765	0.000
Y45.0 Opioids and related analgesics	0.235	0.765	0.000
L29.3 Anogenital pruritus, unspecified	0.233	0.767	0.000
L29.1 Pruritus scroti	0.233	0.767	0.000
L65 Other nonscarring hair loss	0.232	0.767	0.000
Q35-Q37 Cleft lip and cleft palate	0.232	0.768	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.232	0.768	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.231	0.769	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.231	0.769	0.000
I72.2 Aneurysm of renal artery	0.231	0.769	0.000
I72.1 Aneurysm of artery of upper extremity	0.231	0.769	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.231	0.769	0.000
L10-L14 Bullous disorders	0.230	0.769	0.000
L71.0 Perioral dermatitis	0.230	0.769	0.000
I82 Other venous embolism and thrombosis	0.230	0.770	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.230	0.770	0.000
G03 Meningitis due to other and unspecified causes	0.230	0.770	0.000
X60-X84 Intentional self-harm	0.230	0.770	0.000
F68 Other disorders of adult personality and behaviour	0.230	0.770	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.230	0.770	0.000
F65 Disorders of sexual preference	0.230	0.770	0.000
F63 Habit and impulse disorders	0.230	0.770	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.230	0.770	0.000
F61 Mixed and other personality disorders	0.230	0.770	0.000
V80-V89 Other land transport accidents	0.230	0.770	0.000
V43 Car occupant injured in collision with car, pick-up truck or van	0.229	0.771	0.000
L03.3 Cellulitis of trunk	0.229	0.771	0.000
I99 Other and unspecified disorders of circulatory system	0.229	0.771	0.000
Q25.1 Coarctation of aorta	0.229	0.771	0.000
L70 Acne	0.228	0.772	0.000
E61.2 Magnesium deficiency	0.226	0.773	0.001
V01-V09 Pedestrian injured in transport accident	0.226	0.773	0.000
L73.1 Pseudofolliculitis barbae	0.226	0.774	0.000
L73.0 Acne keloid	0.226	0.774	0.000
I87.8 Other specified disorders of veins	0.226	0.774	0.000
W75-W84 Other accidental threats to breathing	0.226	0.774	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.226	0.774	0.000
I70.9 Generalised and unspecified atherosclerosis	0.224	0.775	0.000
I70.8 Atherosclerosis of other arteries	0.224	0.775	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.224	0.776	0.000
L04.9 Acute lymphadenitis, unspecified	0.224	0.776	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.224	0.776	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.224	0.776	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.224	0.776	0.000
F60.3 Emotionally unstable personality disorder	0.223	0.777	0.000
L41.9 Parapsoriasis, unspecified	0.138	0.777	0.086
L41.8 Other parapsoriasis	0.138	0.777	0.086
L41.5 Retiform parapsoriasis	0.138	0.777	0.086
L41.4 Large plaque parapsoriasis	0.138	0.777	0.086
L41.3 Small plaque parapsoriasis	0.138	0.777	0.086
L41.2 Lymphomatoid papulosis	0.138	0.777	0.086
L41.1 Pityriasis lichenoides chronica	0.138	0.777	0.086
L41.0 Pityriasis lichenoides et varioliformis acuta	0.138	0.777	0.086
L44.9 Papulosquamous disorder, unspecified	0.138	0.777	0.086
L44.8 Other specified papulosquamous disorders	0.138	0.777	0.086
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.138	0.777	0.086
L44.3 Lichen ruber moniliformis	0.138	0.777	0.086
L44.2 Lichen striatus	0.138	0.777	0.086
L44.1 Lichen nitidus	0.138	0.777	0.086
L44.0 Pityriasis rubra pilaris	0.138	0.777	0.086
Q30-Q34 Congenital malformations of the respiratory system	0.223	0.777	0.000
L25 Unspecified contact dermatitis	0.223	0.777	0.000
L04.1 Acute lymphadenitis of trunk	0.223	0.777	0.000
F70-F79 Mental retardation	0.223	0.777	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.222	0.777	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.222	0.778	0.000
Y45.2 Propionic acid derivatives	0.222	0.778	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.222	0.778	0.000
I72.0 Aneurysm of carotid artery	0.222	0.778	0.000
F60.6 Anxious [avoidant] personality disorder	0.222	0.778	0.000
U88 Agent resistant to multiple antibiotics	0.221	0.779	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.221	0.779	0.000
F11.1 Harmful use	0.221	0.779	0.000
I74.8 Embolism and thrombosis of other arteries	0.220	0.780	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.220	0.780	0.000
Q26 Congenital malformations of great veins	0.220	0.780	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.220	0.780	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.220	0.780	0.000
F84 Pervasive developmental disorders	0.220	0.780	0.000
L01 Impetigo	0.220	0.780	0.000
L00 Staphylococcal scalded skin syndrome	0.220	0.780	0.000
X00-X09 Exposure to smoke, fire and flames	0.219	0.780	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.219	0.781	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.219	0.781	0.000
L20.9 Atopic dermatitis, unspecified	0.219	0.781	0.000
L43.3 Subacute (active) lichen planus	0.164	0.781	0.055
L43.2 Lichenoid drug reaction	0.164	0.781	0.055
L43.1 Bullous lichen planus	0.164	0.781	0.055
L43.0 Hypertrophic lichen planus	0.164	0.781	0.055
Y79 Orthopaedic devices associated with adverse incidents	0.219	0.781	0.000
L30 Other dermatitis	0.219	0.781	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.218	0.782	0.000
G06.1 Intraspinal abscess and granuloma	0.218	0.782	0.000
V28 Motorcycle rider injured in noncollision transport accident	0.218	0.782	0.000
L28.0 Lichen simplex chronicus	0.218	0.782	0.000
E61.9 Deficiency of nutrient element, unspecified	0.217	0.783	0.001
E61.8 Deficiency of other specified nutrient elements	0.217	0.783	0.001
E61.7 Deficiency of multiple nutrient elements	0.217	0.783	0.001
E61.6 Vanadium deficiency	0.217	0.783	0.001
E61.5 Molybdenum deficiency	0.217	0.783	0.001
E61.4 Chromium deficiency	0.217	0.783	0.001
E61.3 Manganese deficiency	0.217	0.783	0.001
E61.0 Copper deficiency	0.217	0.783	0.001
V70-V79 Bus occupant injured in transport accident	0.217	0.783	0.000
Q89 Other congenital malformations, not elsewhere classified	0.217	0.783	0.000
I87.1 Compression of vein	0.216	0.784	0.000
I88.8 Other nonspecific lymphadenitis	0.216	0.784	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.216	0.784	0.000
L43.9 Lichen planus, unspecified	0.206	0.784	0.010
F18 Mental and behavioural disorders due to use of volatile solvents	0.215	0.784	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.215	0.784	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations