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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16854874
log Bayes Factor = 12.5904
Chromosome 3   position 143,774,531  (GRCh37) Explore rs16854874 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
G90-G99 Other disorders of the nervous system
0.993 0.007 0.000
G93 Other disorders of brain
0.992 0.008 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
K70-K77 Diseases of liver
0.983 0.017 0.000
S00-S09 Injuries to the head
0.982 0.018 0.000
G93.3 Postviral fatigue syndrome
0.981 0.019 0.000
Chapter XI Diseases of the digestive system
0.981 0.019 0.000
Chapter VII Diseases of the eye and adnexa
0.980 0.020 0.000
M20-M25 Other joint disorders
0.978 0.022 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.978 0.022 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.967 0.033 0.000
K70 Alcoholic liver disease
0.966 0.034 0.000
H43-H45 Disorders of vitreous body and globe
0.965 0.035 0.000
Chapter XXII Codes for special purposes
0.961 0.039 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.958 0.042 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.956 0.044 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.954 0.046 0.000
A30-A49 Other bacterial diseases
0.950 0.050 0.000
S02 Fracture of skull and facial bones
0.948 0.052 0.000
K65-K67 Diseases of peritoneum
0.948 0.052 0.000
Y95 Nosocomial condition
0.944 0.056 0.000
H43 Disorders of vitreous body
0.943 0.057 0.000
M25 Other joint disorders, not elsewhere classified
0.941 0.059 0.000
S40-S49 Injuries to the shoulder and upper arm
0.939 0.061 0.000
S80-S89 Injuries to the knee and lower leg
0.936 0.064 0.000
K70.9 Alcoholic liver disease, unspecified
0.933 0.067 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.930 0.070 0.000
G40-G47 Episodic and paroxysmal disorders
0.929 0.071 0.000
H43.8 Other disorders of vitreous body
0.925 0.075 0.000
Chapter V Mental and behavioural disorders
0.919 0.081 0.000
Y86 Sequelae of other accidents
0.916 0.084 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.914 0.085 0.000
K74 Fibrosis and cirrhosis of liver
0.913 0.087 0.000
G40 Epilepsy
0.913 0.087 0.000
N32 Other disorders of bladder
0.911 0.089 0.000
N32.0 Bladder-neck obstruction
0.911 0.089 0.000
U80 Agent resistant to penicillin and related antibiotics
0.911 0.089 0.000
N30-N39 Other diseases of urinary system
0.910 0.090 0.000
D50-D53 Nutritional anaemias
0.910 0.090 0.000
M25.7 Osteophyte
0.909 0.091 0.000
K66 Other disorders of peritoneum
0.907 0.093 0.000
Chapter XIV Diseases of the genitourinary system
0.905 0.095 0.000
A41 Other septicaemia
0.904 0.096 0.000
S01 Open wound of head
0.904 0.096 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.900 0.100 0.000
M45-M49 Spondylopathies
0.899 0.101 0.000
M24 Other specific joint derangements
0.899 0.101 0.000
S20-S29 Injuries to the thorax
0.897 0.103 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.893 0.107 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.892 0.108 0.000
K66.0 Peritoneal adhesions
0.888 0.112 0.000
S81 Open wound of lower leg
0.886 0.114 0.000
K76 Other diseases of liver
0.886 0.114 0.000
G40.9 Epilepsy, unspecified
0.885 0.115 0.000
G93.9 Disorder of brain, unspecified
0.884 0.116 0.000
H52 Disorders of refraction and accommodation
0.883 0.117 0.000
K75 Other inflammatory liver diseases
0.883 0.117 0.000
T93 Sequelae of injuries of lower limb
0.880 0.120 0.000
M05-M14 Inflammatory polyarthropathies
0.877 0.123 0.000
U80.1 Methicillin resistant agent
0.877 0.123 0.000
G93.2 Benign intracranial hypertension
0.869 0.131 0.000
S60-S69 Injuries to the wrist and hand
0.866 0.134 0.000
M31 Other necrotising vasculopathies
0.862 0.138 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.861 0.139 0.000
S40 Superficial injury of shoulder and upper arm
0.861 0.139 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.860 0.140 0.000
X60-X84 Intentional self-harm
0.859 0.141 0.000
K74.6 Other and unspecified cirrhosis of liver
0.857 0.143 0.000
Y85 Sequelae of transport accidents
0.857 0.143 0.000
S06 Intracranial injury
0.855 0.145 0.000
S81.0 Open wound of knee
0.848 0.152 0.000
S02.0 Fracture of vault of skull
0.847 0.153 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.838 0.162 0.000
S32 Fracture of lumbar spine and pelvis
0.836 0.164 0.000
S01.8 Open wound of other parts of head
0.834 0.166 0.000
M80-M85 Disorders of bone density and structure
0.833 0.167 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.831 0.169 0.000
S02.4 Fracture of malar and maxillary bones
0.830 0.170 0.000
H44 Disorders of globe
0.829 0.171 0.000
B15-B19 Viral hepatitis
0.829 0.171 0.000
H52.1 Myopia
0.828 0.172 0.000
S01.5 Open wound of lip and oral cavity
0.826 0.173 0.000
Y88 Sequelae of surgical and medical care as external cause
0.825 0.175 0.000
D51 Vitamin B12 deficiency anaemia
0.823 0.177 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.823 0.177 0.000
B95-B98 Bacterial, viral and other infectious agents
0.823 0.177 0.000
M25.77 Osteophyte (Ankle and foot)
0.821 0.179 0.000
W20-W49 Exposure to inanimate mechanical forces
0.816 0.184 0.000
K72 Hepatic failure, not elsewhere classified
0.815 0.185 0.000
W00-W19 Falls
0.815 0.185 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.814 0.186 0.000
M50-M54 Other dorsopathies
0.814 0.186 0.000
M10 Gout
0.812 0.188 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.812 0.188 0.000
K76.6 Portal hypertension
0.812 0.188 0.000
M24.0 Loose body in joint
0.811 0.189 0.000
U80.0 Penicillin resistant agent
0.811 0.189 0.000
S10-S19 Injuries to the neck
0.810 0.190 0.000
N36 Other disorders of urethra
0.809 0.191 0.000
M25.78 Osteophyte (Other)
0.806 0.194 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.804 0.195 0.000
N39 Other disorders of urinary system
0.804 0.196 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.804 0.196 0.000
K70.0 Alcoholic fatty liver
0.803 0.197 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.802 0.198 0.000
M86-M90 Other osteopathies
0.802 0.198 0.000
G90 Disorders of autonomic nervous system
0.802 0.198 0.000
M33 Dermatopolymyositis
0.802 0.198 0.000
E20-E35 Disorders of other endocrine glands
0.800 0.200 0.000
K70.3 Alcoholic cirrhosis of liver
0.800 0.200 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.800 0.200 0.000
B99-B99 Other infectious diseases
0.800 0.200 0.000
D50 Iron deficiency anaemia
0.800 0.200 0.000
M46 Other inflammatory spondylopathies
0.799 0.201 0.000
T39.1 4-Aminophenol derivatives
0.799 0.201 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.797 0.203 0.000
S32.5 Fracture of pubis
0.797 0.203 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.795 0.204 0.000
F30-F39 Mood [affective] disorders
0.795 0.205 0.000
K76.9 Liver disease, unspecified
0.795 0.205 0.000
M65-M68 Disorders of synovium and tendon
0.793 0.207 0.000
K65 Peritonitis
0.787 0.213 0.000
N32.3 Diverticulum of bladder
0.786 0.214 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.785 0.215 0.000
V40-V49 Car occupant injured in transport accident
0.784 0.216 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.784 0.216 0.000
S89 Other and unspecified injuries of lower leg
0.783 0.217 0.000
M40-M43 Deforming dorsopathies
0.782 0.218 0.000
G20-G26 Extrapyramidal and movement disorders
0.781 0.218 0.000
V10-V19 Pedal cyclist injured in transport accident
0.781 0.219 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.779 0.221 0.000
M45 Ankylosing spondylitis
0.779 0.221 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.777 0.223 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.776 0.224 0.000
Y52 Agents primarily affecting the cardiovascular system
0.776 0.224 0.000
S64 Injury of nerves at wrist and hand level
0.774 0.226 0.000
S02.00 Fracture of vault of skull (closed)
0.774 0.226 0.000
H43.1 Vitreous haemorrhage
0.772 0.228 0.000
G93.6 Cerebral oedema
0.771 0.229 0.000
T92 Sequelae of injuries of upper limb
0.771 0.229 0.000
W50-W64 Exposure to animate mechanical forces
0.769 0.230 0.000
H52.2 Astigmatism
0.769 0.231 0.000
S32.50 Fracture of pubis (closed)
0.769 0.231 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.768 0.232 0.000
K70.4 Alcoholic hepatic failure
0.767 0.233 0.000
T66-T78 Other and unspecified effects of external causes
0.767 0.233 0.000
H55-H59 Other disorders of eye and adnexa
0.766 0.234 0.000
M10.9 Gout, unspecified
0.766 0.234 0.000
A40 Streptococcal septicaemia
0.766 0.234 0.000
M31.6 Other giant cell arteritis
0.764 0.236 0.000
A65-A69 Other spirochaetal diseases
0.764 0.236 0.000
F03 Unspecified dementia
0.762 0.238 0.000
V80-V89 Other land transport accidents
0.761 0.239 0.000
M25.0 Haemarthrosis
0.761 0.239 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.760 0.240 0.000
S61 Open wound of wrist and hand
0.759 0.241 0.000
N39.8 Other specified disorders of urinary system
0.759 0.241 0.000
T79-T79 Certain early complications of trauma
0.757 0.243 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.755 0.245 0.000
Chapter VIII Diseases of the ear and mastoid process
0.754 0.246 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.753 0.247 0.000
S90-S99 Injuries to the ankle and foot
0.753 0.247 0.000
N32.1 Vesicointestinal fistula
0.752 0.248 0.000
S29 Other and unspecified injuries of thorax
0.751 0.248 0.000
S86 Injury of muscle and tendon at lower leg level
0.749 0.251 0.000
A80-A89 Viral infections of the central nervous system
0.749 0.251 0.000
T98 Sequelae of other and unspecified effects of external causes
0.747 0.252 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.746 0.254 0.000
D50.8 Other iron deficiency anaemias
0.746 0.254 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.746 0.254 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.745 0.255 0.000
S02.6 Fracture of mandible
0.743 0.257 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.743 0.257 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.742 0.258 0.000
Y00-Y09 Assault
0.742 0.258 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.740 0.260 0.000
X78 Intentional self-harm by sharp object
0.740 0.260 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.739 0.261 0.000
M23 Internal derangement of knee
0.738 0.262 0.000
Y85.0 Sequelae of motor-vehicle accident
0.737 0.263 0.000
S02.3 Fracture of orbital floor
0.736 0.264 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.736 0.264 0.000
A49 Bacterial infection of unspecified site
0.734 0.266 0.000
M25.71 Osteophyte (Shoulder region)
0.734 0.266 0.000
M25.4 Effusion of joint
0.734 0.266 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.733 0.267 0.000
K74.3 Primary biliary cirrhosis
0.732 0.268 0.000
A00-A09 Intestinal infectious diseases
0.732 0.268 0.000
N35 Urethral stricture
0.732 0.268 0.000
D69 Purpura and other haemorrhagic conditions
0.732 0.268 0.000
H44.2 Degenerative myopia
0.731 0.269 0.000
S43.0 Dislocation of shoulder joint
0.730 0.270 0.000
K65.0 Acute peritonitis
0.730 0.270 0.000
S05 Injury of eye and orbit
0.729 0.271 0.000
G93.4 Encephalopathy, unspecified
0.728 0.272 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.728 0.272 0.000
X50-X57 Overexertion, travel and privation
0.727 0.273 0.000
N34 Urethritis and urethral syndrome
0.726 0.274 0.000
Y48 Anaesthetics and therapeutic gases
0.725 0.275 0.000
Chapter XXI Factors influencing health status and contact with health services
0.725 0.275 0.000
K75.9 Inflammatory liver disease, unspecified
0.725 0.275 0.000
M25.8 Other specified joint disorders
0.725 0.275 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.723 0.277 0.000
M48 Other spondylopathies
0.723 0.277 0.000
S02.1 Fracture of base of skull
0.722 0.278 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.721 0.279 0.000
S02.5 Fracture of tooth
0.721 0.279 0.000
E50-E64 Other nutritional deficiencies
0.721 0.279 0.000
M80 Osteoporosis with pathological fracture
0.719 0.281 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.719 0.281 0.000
F33 Recurrent depressive disorder
0.718 0.281 0.000
T90 Sequelae of injuries of head
0.718 0.282 0.000
E22 Hyperfunction of pituitary gland
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.715 0.285 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.715 0.285 0.000
H40-H42 Glaucoma
0.714 0.286 0.000
M21 Other acquired deformities of limbs
0.714 0.286 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.714 0.286 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.714 0.286 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.713 0.287 0.000
G93.0 Cerebral cysts
0.712 0.288 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.712 0.288 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.712 0.288 0.000
G92 Toxic encephalopathy
0.712 0.288 0.000
A41.8 Other specified septicaemia
0.712 0.288 0.000
G93.7 Reye's syndrome
0.711 0.289 0.000
G93.5 Compression of brain
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.289 0.000
B50-B64 Protozoal diseases
0.711 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.289 0.000
A15-A19 Tuberculosis
0.711 0.289 0.000
F80-F89 Disorders of psychological development
0.711 0.289 0.000
M91-M94 Chondropathies
0.711 0.289 0.000
M60-M63 Disorders of muscles
0.711 0.289 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.709 0.290 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.709 0.291 0.000
H52.7 Disorder of refraction, unspecified
0.708 0.292 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.707 0.292 0.000
S06.2 Diffuse brain injury
0.707 0.293 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.707 0.293 0.000
K76.7 Hepatorenal syndrome
0.706 0.294 0.000
S20 Superficial injury of thorax
0.705 0.295 0.000
K77 Liver disorders in diseases classified elsewhere
0.705 0.295 0.000
K73 Chronic hepatitis, not elsewhere classified
0.705 0.295 0.000
K71 Toxic liver disease
0.705 0.295 0.000
K75.4 Autoimmune hepatitis
0.704 0.296 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.704 0.296 0.000
S81.9 Open wound of lower leg, part unspecified
0.704 0.296 0.000
S08 Traumatic amputation of part of head
0.704 0.296 0.000
S07 Crushing injury of head
0.704 0.296 0.000
S04 Injury of cranial nerves
0.704 0.296 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.704 0.296 0.000
N99-N99 Other disorders of the genitourinary system
0.704 0.296 0.000
G41 Status epilepticus
0.703 0.297 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.702 0.298 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.701 0.298 0.000
M32 Systemic lupus erythematosus
0.701 0.298 0.000
M30 Polyarteritis nodosa and related conditions
0.701 0.298 0.000
Y89 Sequelae of other external causes
0.701 0.298 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.701 0.298 0.000
F70-F79 Mental retardation
0.701 0.299 0.000
E23 Hypofunction and other disorders of pituitary gland
0.700 0.300 0.000
M25.72 Osteophyte (Upper arm)
0.697 0.303 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.697 0.303 0.000
B65-B83 Helminthiases
0.696 0.304 0.000
S27 Injury of other and unspecified intrathoracic organs
0.696 0.304 0.000
N40-N51 Diseases of male genital organs
0.696 0.304 0.000
G91 Hydrocephalus
0.695 0.304 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.694 0.306 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.693 0.306 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.693 0.306 0.000
Y98 Lifestyle-related condition
0.693 0.306 0.000
Y97 Environmental-pollution-related condition
0.693 0.306 0.000
Y96 Work-related condition
0.693 0.306 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.693 0.307 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.692 0.308 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.692 0.308 0.000
M24.07 Loose body in joint (Ankle and foot)
0.692 0.308 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.692 0.308 0.000
T91 Sequelae of injuries of neck and trunk
0.690 0.310 0.000
K74.5 Biliary cirrhosis, unspecified
0.689 0.311 0.000
M82 Osteoporosis in diseases classified elsewhere
0.689 0.311 0.000
S70-S79 Injuries to the hip and thigh
0.689 0.311 0.000
M25.3 Other instability of joint
0.689 0.311 0.000
M67 Other disorders of synovium and tendon
0.688 0.312 0.000
G30-G32 Other degenerative diseases of the nervous system
0.687 0.313 0.000
K75.0 Abscess of liver
0.687 0.313 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.687 0.313 0.000
M05 Seropositive rheumatoid arthritis
0.687 0.313 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.687 0.313 0.000
G40.5 Special epileptic syndromes
0.686 0.314 0.000
T95 Sequelae of burns, corrosions and frostbite
0.686 0.314 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.686 0.314 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.686 0.314 0.000
X20-X29 Contact with venomous animals and plants
0.685 0.315 0.000
A41.9 Septicaemia, unspecified
0.685 0.315 0.000
N32.8 Other specified disorders of bladder
0.684 0.316 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.684 0.316 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.684 0.316 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.684 0.316 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.684 0.316 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.684 0.316 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.684 0.316 0.000
T36 Poisoning by systemic antibiotics
0.684 0.316 0.000
S40.0 Contusion of shoulder and upper arm
0.684 0.316 0.000
B18 Chronic viral hepatitis
0.683 0.317 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.683 0.317 0.000
W45 Foreign body or object entering through skin
0.683 0.317 0.000
M00-M03 Infectious arthropathies
0.682 0.318 0.000
S01.9 Open wound of head, part unspecified
0.682 0.318 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.682 0.318 0.000
K75.8 Other specified inflammatory liver diseases
0.681 0.319 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.681 0.319 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.681 0.319 0.000
S41 Open wound of shoulder and upper arm
0.681 0.319 0.000
A48 Other bacterial diseases, not elsewhere classified
0.681 0.319 0.000
A44 Bartonellosis
0.681 0.319 0.000
A43 Nocardiosis
0.681 0.319 0.000
A42 Actinomycosis
0.681 0.319 0.000
A39 Meningococcal infection
0.681 0.319 0.000
A37 Whooping cough
0.681 0.319 0.000
A36 Diphtheria
0.681 0.319 0.000
A32 Listeriosis
0.681 0.319 0.000
A31 Infection due to other mycobacteria
0.681 0.319 0.000
A30 Leprosy [Hansen's disease]
0.681 0.319 0.000
A38 Scarlet fever
0.681 0.319 0.000
A35 Other tetanus
0.681 0.319 0.000
A34 Obstetrical tetanus
0.681 0.319 0.000
A33 Tetanus neonatorum
0.681 0.319 0.000
M87 Osteonecrosis
0.680 0.320 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.680 0.320 0.000
S02.7 Multiple fractures involving skull and facial bones
0.680 0.320 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.680 0.320 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.679 0.321 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.679 0.321 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.678 0.321 0.000
G93.8 Other specified disorders of brain
0.678 0.321 0.000
K72.9 Hepatic failure, unspecified
0.678 0.322 0.000
M50 Cervical disk disorders
0.678 0.322 0.000
S06.8 Other intracranial injuries
0.677 0.323 0.000
M53 Other dorsopathies, not elsewhere classified
0.677 0.323 0.000
H43.9 Disorder of vitreous body, unspecified
0.676 0.324 0.000
H43.2 Crystalline deposits in vitreous body
0.676 0.324 0.000
H43.0 Vitreous prolapse
0.676 0.324 0.000
S01.2 Open wound of nose
0.676 0.324 0.000
S02.8 Fractures of other skull and facial bones
0.676 0.324 0.000
M25.9 Joint disorder, unspecified
0.675 0.325 0.000
M25.2 Flail joint
0.675 0.325 0.000
M25.1 Fistula of joint
0.675 0.325 0.000
M33.1 Other dermatomyositis
0.675 0.325 0.000
S61.1 Open wound of finger(s) with damage to nail
0.675 0.325 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.674 0.325 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.674 0.326 0.000
S48 Traumatic amputation of shoulder and upper arm
0.673 0.327 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.673 0.327 0.000
S44 Injury of nerves at shoulder and upper arm level
0.673 0.327 0.000
S47 Crushing injury of shoulder and upper arm
0.673 0.327 0.000
G96 Other disorders of central nervous system
0.673 0.327 0.000
D52 Folate deficiency anaemia
0.673 0.327 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.672 0.328 0.000
N36.0 Urethral fistula
0.672 0.328 0.000
S88 Traumatic amputation of lower leg
0.671 0.329 0.000
S87 Crushing injury of lower leg
0.671 0.329 0.000
S85 Injury of blood vessels at lower leg level
0.671 0.329 0.000
S84 Injury of nerves at lower leg level
0.671 0.329 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.671 0.329 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.669 0.331 0.000
N50 Other disorders of male genital organs
0.669 0.331 0.000
F01 Vascular dementia
0.668 0.332 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.668 0.332 0.000
M34 Systemic sclerosis
0.668 0.332 0.000
W17 Other fall from one level to another
0.667 0.333 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.667 0.333 0.000
U50 Level of care administered to neonates
0.667 0.333 0.000
U07 Emergency use of U07
0.667 0.333 0.000
U06 Emergency use of U06
0.667 0.333 0.000
U04 Severe acute respiratory syndrome [SARS]
0.667 0.333 0.000
U52 First in a series of a regular day/night admissions
0.667 0.333 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.666 0.334 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.666 0.334 0.000
D80-D89 Certain disorders involving the immune mechanism
0.666 0.334 0.000
W07 Fall involving chair
0.664 0.336 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.664 0.336 0.000
F02 Dementia in other diseases classified elsewhere
0.664 0.336 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.663 0.337 0.000
W10 Fall on and from stairs and steps
0.663 0.337 0.000
B99 Other and unspecified infectious diseases
0.663 0.337 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.662 0.338 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.661 0.339 0.000
B35-B49 Mycoses
0.661 0.339 0.000
M46.4 Discitis, unspecified
0.660 0.340 0.000
M23.8 Other internal derangements of knee
0.659 0.341 0.000
S01.1 Open wound of eyelid and periocular area
0.659 0.341 0.000
G95 Other diseases of spinal cord
0.659 0.341 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.659 0.341 0.000
G40.8 Other epilepsy
0.658 0.341 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.658 0.342 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.658 0.342 0.000
M13 Other arthritis
0.657 0.343 0.000
H51 Other disorders of binocular movement
0.656 0.344 0.000
T93.2 Sequelae of other fractures of lower limb
0.656 0.344 0.000
M24.02 Loose body in joint (Upper arm)
0.655 0.345 0.000
M07 Psoriatic and enteropathic arthropathies
0.655 0.345 0.000
X78.0 Home
0.655 0.345 0.000
K74.4 Secondary biliary cirrhosis
0.655 0.345 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.655 0.345 0.000
K74.1 Hepatic sclerosis
0.655 0.345 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.655 0.345 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.655 0.345 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.655 0.345 0.000
M31.3 Wegener's granulomatosis
0.654 0.346 0.000
N32.4 Rupture of bladder, nontraumatic
0.653 0.347 0.000
N32.2 Vesical fistula, not elsewhere classified
0.653 0.347 0.000
M41 Scoliosis
0.653 0.347 0.000
Y44 Agents primarily affecting blood constituents
0.653 0.347 0.000
N37 Urethral disorders in diseases classified elsewhere
0.653 0.347 0.000
N33 Bladder disorders in diseases classified elsewhere
0.653 0.347 0.000
D53 Other nutritional anaemias
0.652 0.348 0.000
K50-K52 Noninfective enteritis and colitis
0.652 0.348 0.000
Y40 Systemic antibiotics
0.652 0.348 0.000
M10.90 Gout, unspecified (Multiple sites)
0.652 0.348 0.000
M25.79 Osteophyte (Site unspecified)
0.651 0.348 0.000
M25.73 Osteophyte (Forearm)
0.651 0.348 0.000
M25.70 Osteophyte (Multiple sites)
0.651 0.348 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.651 0.349 0.000
M24.5 Contracture of joint
0.651 0.349 0.000
T39.0 Salicylates
0.651 0.349 0.000
K66.9 Disorder of peritoneum, unspecified
0.650 0.350 0.000
K66.1 Haemoperitoneum
0.650 0.350 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.650 0.350 0.000
D55-D59 Haemolytic anaemias
0.649 0.351 0.000
H01 Other inflammation of eyelid
0.649 0.351 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.649 0.351 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.649 0.351 0.000
M24.2 Disorder of ligament
0.648 0.351 0.000
A41.4 Septicaemia due to anaerobes
0.648 0.352 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.648 0.352 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.648 0.352 0.000
S29.9 Unspecified injury of thorax
0.648 0.352 0.000
N39.0 Urinary tract infection, site not specified
0.647 0.353 0.000
D68 Other coagulation defects
0.647 0.353 0.000
F31 Bipolar affective disorder
0.646 0.354 0.000
G44 Other headache syndromes
0.646 0.354 0.000
Y59 Other and unspecified vaccines and biological substances
0.645 0.354 0.000
Y58 Bacterial vaccines
0.645 0.354 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.645 0.354 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.645 0.354 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.645 0.354 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.645 0.354 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.645 0.354 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.645 0.355 0.000
E00-E07 Disorders of thyroid gland
0.645 0.355 0.000
M49 Spondylopathies in diseases classified elsewhere
0.645 0.355 0.000
M24.9 Joint derangement, unspecified
0.644 0.356 0.000
M24.7 Protrusio acetabuli
0.644 0.356 0.000
M24.6 Ankylosis of joint
0.644 0.356 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.643 0.357 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.643 0.357 0.000
S26 Injury of heart
0.643 0.357 0.000
S25 Injury of blood vessels of thorax
0.643 0.357 0.000
S24 Injury of nerves and spinal cord at thorax level
0.643 0.357 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.643 0.357 0.000
S21 Open wound of thorax
0.643 0.357 0.000
H65-H75 Diseases of middle ear and mastoid
0.643 0.357 0.000
S32.4 Fracture of acetabulum
0.643 0.357 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.643 0.357 0.000
H57 Other disorders of eye and adnexa
0.641 0.359 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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