TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs16870123
log Bayes Factor = 72.6767
Chromosome 6   position 32,359,460  (GRCh37) Explore rs16870123 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
C44.7 Skin of lower limb, including hip
1.000 0.000 0.000
K50-K52 Noninfective enteritis and colitis
0.999 0.001 0.000
K50 Crohn's disease [regional enteritis]
0.999 0.001 0.000
K50.1 Crohn's disease of large intestine
0.999 0.001 0.000
Z93.2 Ileostomy status
0.994 0.006 0.000
C44.4 Skin of scalp and neck
0.993 0.007 0.000
K51.4 Pseudopolyposis of colon
0.992 0.008 0.000
E10.3 With ophthalmic complications
0.000 0.011 0.989
E10.1 With ketoacidosis
0.000 0.011 0.989
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.989 0.011 0.000
C44.2 Skin of ear and external auricular canal
0.987 0.013 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.982 0.018 0.000
C44.5 Skin of trunk
0.974 0.026 0.000
C44.6 Skin of upper limb, including shoulder
0.973 0.027 0.000
K51.8 Other ulcerative colitis
0.953 0.047 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.951 0.049 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.940 0.060 0.000
K51.2 Ulcerative (chronic) proctitis
0.938 0.062 0.000
C83.3 Large cell (diffuse)
0.937 0.063 0.000
C44.0 Skin of lip
0.934 0.066 0.000
K50.9 Crohn's disease, unspecified
0.928 0.072 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.076 0.924
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.923 0.077 0.000
D86 Sarcoidosis
0.000 0.083 0.917
D86.0 Sarcoidosis of lung
0.000 0.093 0.907
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.904 0.096 0.000
C82.0 Small cleaved cell, follicular
0.892 0.108 0.000
E10-E14 Diabetes mellitus
0.000 0.113 0.887
K52 Other non-infective gastro-enteritis and colitis
0.872 0.128 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.152 0.848
E16 Other disorders of pancreatic internal secretion
0.000 0.153 0.847
E16.2 Hypoglycaemia, unspecified
0.000 0.153 0.847
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.154 0.846
E10.8 With unspecified complications
0.000 0.163 0.837
K51.5 Mucosal proctocolitis
0.826 0.174 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.191 0.809
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.809 0.191 0.000
E27 Other disorders of adrenal gland
0.000 0.201 0.799
C82.3 Follicular lymphoma grade IIIa
0.794 0.206 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.206 0.794
C44.9 Malignant neoplasm of skin, unspecified
0.787 0.213 0.000
K52.1 Toxic gastro-enteritis and colitis
0.785 0.215 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.226 0.774
C44.1 Skin of eyelid, including canthus
0.772 0.228 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.228 0.772
D50-D53 Nutritional anaemias
0.000 0.231 0.769
E10.0 With coma
0.000 0.232 0.768
K52.8 Other specified non-infective gastro-enteritis and colitis
0.766 0.234 0.000
K90 Intestinal malabsorption
0.000 0.240 0.760
D80-D89 Certain disorders involving the immune mechanism
0.000 0.245 0.755
E10.4 With neurological complications
0.000 0.245 0.755
E10.6 With other specified complications
0.000 0.251 0.749
D50 Iron deficiency anaemia
0.000 0.260 0.740
D50.9 Iron deficiency anaemia, unspecified
0.000 0.263 0.737
E22 Hyperfunction of pituitary gland
0.000 0.265 0.735
K52.3 Indeterminate colitis
0.733 0.267 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.268 0.732
C83.1 Small cleaved cell (diffuse)
0.725 0.274 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.282 0.718
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.715 0.285 0.000
C85.1 B-cell lymphoma, unspecified
0.714 0.285 0.000
K50.8 Other Crohn's disease
0.713 0.287 0.000
C82.2 Large cell, follicular
0.712 0.288 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.712 0.288 0.000
C81 Hodgkin's disease
0.709 0.291 0.000
M06.9 Rheumatoid arthritis, unspecified
0.706 0.294 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.705 0.295 0.000
C82.6 Cutaneous follicle centre lymphoma
0.704 0.296 0.000
C82.5 Diffuse follicle centre lymphoma
0.704 0.296 0.000
C82.4 Follicular lymphoma grade IIIb
0.704 0.296 0.000
E10.2 With renal complications
0.000 0.299 0.701
M06 Other rheumatoid arthritis
0.696 0.304 0.000
M06.0 Seronegative rheumatoid arthritis
0.691 0.309 0.000
E13 Other specified diabetes mellitus
0.000 0.311 0.689
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.687 0.313 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.684 0.316 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.682 0.318 0.000
C94 Other leukaemias of specified cell type
0.682 0.318 0.000
C93 Monocytic leukaemia
0.682 0.318 0.000
C86 Other specified types of T/NK-cell lymphoma
0.682 0.318 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.680 0.320 0.000
E16.1 Other hypoglycaemia
0.000 0.321 0.679
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.326 0.674
C83.6 Undifferentiated (diffuse)
0.674 0.326 0.000
C83.5 Lymphoblastic (diffuse)
0.674 0.326 0.000
C83.4 Immunoblastic (diffuse)
0.674 0.326 0.000
C83.2 Mixed small and large cell (diffuse)
0.674 0.326 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.329 0.671
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.662 0.338 0.000
C85.0 Lymphosarcoma
0.662 0.338 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.343 0.657
D86.3 Sarcoidosis of skin
0.000 0.343 0.657
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.343 0.657
D86.1 Sarcoidosis of lymph nodes
0.000 0.343 0.657
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.345 0.655
C83.7 Burkitt's tumour
0.652 0.348 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.650 0.350 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.350 0.650
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.351 0.649
K51.1 Ulcerative (chronic) ileocolitis
0.645 0.355 0.000
E14 Unspecified diabetes mellitus
0.000 0.357 0.643
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.643 0.357 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.641 0.359 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.364 0.636
E10.5 With peripheral circulatory complications
0.000 0.373 0.627
C95 Leukaemia of unspecified cell type
0.626 0.374 0.000
E27.2 Addisonian crisis
0.000 0.376 0.624
E24 Cushing's syndrome
0.000 0.377 0.623
C84 Peripheral and cutaneous T-cell lymphomas
0.619 0.381 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.389 0.610
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.393 0.607
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.393 0.607
E16.4 Abnormal secretion of gastrin
0.000 0.393 0.607
E16.3 Increased secretion of glucagon
0.000 0.393 0.607
C43-C44 Melanoma and other malignant neoplasms of skin
0.607 0.393 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.393 0.607
C88 Malignant immunoproliferative diseases
0.601 0.399 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.600 0.399 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.590 0.410 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.588 0.411 0.000
D52 Folate deficiency anaemia
0.000 0.413 0.587
E20 Hypoparathyroidism
0.000 0.420 0.580
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.420 0.580
E32 Diseases of thymus
0.000 0.420 0.580
E31 Polyglandular dysfunction
0.000 0.420 0.580
E30 Disorders of puberty, not elsewhere classified
0.000 0.420 0.580
E25 Adrenogenital disorders
0.000 0.420 0.580
E27.5 Adrenomedullary hyperfunction
0.000 0.427 0.573
E27.0 Other adrenocortical overactivity
0.000 0.427 0.573
K90.8 Other intestinal malabsorption
0.000 0.427 0.572
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.429 0.571
C85.7 Other specified types of non-Hodgkin's lymphoma
0.570 0.430 0.000
C81.1 Nodular sclerosis
0.568 0.432 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.566 0.434 0.000
E40-E46 Malnutrition
0.000 0.439 0.560
E34 Other endocrine disorders
0.000 0.442 0.558
E21.0 Primary hyperparathyroidism
0.000 0.443 0.557
E65-E68 Obesity and other hyperalimentation
0.000 0.444 0.556
E22.0 Acromegaly and pituitary gigantism
0.000 0.444 0.555
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.445 0.555
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.445 0.555
D51.2 Transcobalamin II deficiency
0.000 0.445 0.555
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.445 0.555
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.552 0.448 0.000
E13.9 Without complications
0.000 0.453 0.547
K90.3 Pancreatic steatorrhoea
0.000 0.455 0.545
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.455 0.545
K90.1 Tropical sprue
0.000 0.455 0.545
C81.2 Mixed cellularity
0.542 0.458 0.000
D82 Immunodeficiency associated with other major defects
0.000 0.459 0.541
D81 Combined immunodeficiencies
0.000 0.459 0.541
C81.0 Lymphocytic predominance
0.538 0.462 0.000
E22.1 Hyperprolactinaemia
0.000 0.466 0.534
C90 Multiple myeloma and malignant plasma cell neoplasms
0.532 0.468 0.000
D50.1 Sideropenic dysphagia
0.000 0.469 0.531
D53 Other nutritional anaemias
0.000 0.471 0.529
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.473 0.527
E22.8 Other hyperfunction of pituitary gland
0.000 0.473 0.527
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.525 0.475 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.523 0.477 0.000
E14.9 Without complications
0.000 0.478 0.522
E27.8 Other specified disorders of adrenal gland
0.000 0.480 0.520
C81.7 Other Hodgkin's disease
0.508 0.491 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.508 0.491 0.000
C81.3 Lymphocytic depletion
0.508 0.491 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.501 0.499
M06.8 Other specified rheumatoid arthritis
0.499 0.501 0.000
M06.2 Rheumatoid bursitis
0.499 0.501 0.000
M06.1 Adult-onset Still's disease
0.499 0.501 0.000
E00-E07 Disorders of thyroid gland
0.000 0.501 0.499
M06.08 Seronegative rheumatoid arthritis (Other)
0.495 0.504 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.495 0.504 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.495 0.504 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.495 0.504 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.495 0.504 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.495 0.504 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.495 0.504 0.000
M05-M14 Inflammatory polyarthropathies
0.495 0.505 0.000
D55-D59 Haemolytic anaemias
0.000 0.505 0.495
E13.8 With unspecified complications
0.000 0.506 0.494
E13.7 With multiple complications
0.000 0.506 0.494
E13.6 With other specified complications
0.000 0.506 0.494
E13.5 With peripheral circulatory complications
0.000 0.506 0.494
E13.4 With neurological complications
0.000 0.506 0.494
E13.3 With ophthalmic complications
0.000 0.506 0.494
E13.2 With renal complications
0.000 0.506 0.494
E13.1 With ketoacidosis
0.000 0.506 0.494
E13.0 With coma
0.000 0.506 0.494
E24.9 Cushing's syndrome, unspecified
0.000 0.510 0.490
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.489 0.511 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.489 0.511 0.000
C86.4 Blastic NK-cell lymphoma
0.489 0.511 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.489 0.511 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.489 0.511 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.489 0.511 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.489 0.511 0.000
C93.9 Monocytic leukaemia, unspecified
0.489 0.511 0.000
C93.7 Other monocytic leukaemia
0.489 0.511 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.489 0.511 0.000
C93.2 Subacute monocytic leukaemia
0.489 0.511 0.000
C93.1 Chronic monocytic leukaemia
0.489 0.511 0.000
C93.0 Acute monocytic leukaemia
0.489 0.511 0.000
C94.7 Other specified leukaemias
0.489 0.511 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.489 0.511 0.000
C94.5 Acute myelofibrosis
0.489 0.511 0.000
C94.4 Acute panmyelosis
0.489 0.511 0.000
C94.3 Mast cell leukaemia
0.489 0.511 0.000
C94.2 Acute megakaryoblastic leukaemia
0.489 0.511 0.000
C94.1 Chronic erythraemia
0.489 0.511 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.489 0.511 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.489 0.511 0.000
C96.8 Histiocytic sarcoma
0.489 0.511 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.489 0.511 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.489 0.511 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.489 0.511 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.489 0.511 0.000
C96.3 True histiocytic lymphoma
0.489 0.511 0.000
C96.2 Malignant mast cell tumour
0.489 0.511 0.000
C96.1 Malignant histiocytosis
0.489 0.511 0.000
C96.0 Letterer-Siwe disease
0.489 0.511 0.000
M06.3 Rheumatoid nodule
0.487 0.513 0.000
E29 Testicular dysfunction
0.000 0.516 0.484
E14.3 With ophthalmic complications
0.000 0.522 0.478
D83 Common variable immunodeficiency
0.000 0.528 0.472
M06.4 Inflammatory polyarthropathy
0.471 0.529 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.531 0.469
E21.4 Other specified disorders of parathyroid gland
0.000 0.531 0.469
E21.2 Other hyperparathyroidism
0.000 0.531 0.469
E34.0 Carcinoid syndrome
0.000 0.537 0.463
K52.0 Gastro-enteritis and colitis due to radiation
0.461 0.538 0.000
E14.8 With unspecified complications
0.000 0.538 0.461
E14.7 With multiple complications
0.000 0.538 0.461
E14.2 Withrenal complications
0.000 0.538 0.461
E14.1 With ketoacidosis
0.000 0.538 0.461
E14.0 With coma
0.000 0.538 0.461
C91 Lymphoid leukaemia
0.460 0.539 0.001
D52.9 Folate deficiency anaemia, unspecified
0.000 0.544 0.456
E12.9 Without complications
0.000 0.544 0.456
E12.8 With unspecified complications
0.000 0.544 0.456
E12.7 With multiple complications
0.000 0.544 0.456
E12.6 With other specified complications
0.000 0.544 0.456
E12.5 With peripheral circulatory complications
0.000 0.544 0.456
E12.4 With neurological complications
0.000 0.544 0.456
E12.3 With ophthalmic complications
0.000 0.544 0.456
E12.2 With renal complications
0.000 0.544 0.456
E12.1 With ketoacidosis
0.000 0.544 0.456
E12.0 With coma
0.000 0.544 0.456
D80 Immunodeficiency with predominantly antibody defects
0.000 0.544 0.455
M07 Psoriatic and enteropathic arthropathies
0.454 0.546 0.000
E03 Other hypothyroidism
0.000 0.548 0.452
C95.7 Other leukaemia of unspecified cell type
0.449 0.551 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.449 0.551 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.449 0.551 0.000
C95.0 Acute leukaemia of unspecified cell type
0.449 0.551 0.000
E24.8 Other Cushing's syndrome
0.000 0.553 0.447
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.553 0.447
E24.3 Ectopic ACTH syndrome
0.000 0.553 0.447
E24.2 Drug-induced Cushing's syndrome
0.000 0.553 0.447
E24.1 Nelson's syndrome
0.000 0.553 0.447
E24.0 Pituitary-dependent Cushing's disease
0.000 0.553 0.447
M05 Seropositive rheumatoid arthritis
0.445 0.555 0.000
E14.6 With other specified complications
0.000 0.556 0.444
C84.9 Mature T/NK-cell lymphoma, unspecified
0.444 0.556 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.444 0.556 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.444 0.556 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.444 0.556 0.000
C84.3 Lymphoepithelioid lymphoma
0.444 0.556 0.000
C84.2 T-zone lymphoma
0.444 0.556 0.000
C84.1 Sezary's diease
0.444 0.556 0.000
C84.0 Mycosis fungoides
0.441 0.559 0.000
E14.5 With peripheral circulatory complications
0.000 0.560 0.440
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.438 0.562 0.000
D84 Other immunodeficiencies
0.001 0.564 0.436
C88.9 Malignant immunoproliferative disease, unspecified
0.431 0.569 0.000
C88.7 Other malignant immunoproliferative diseases
0.431 0.569 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.431 0.569 0.000
C88.3 Immunoproliferative small intestinal disease
0.431 0.569 0.000
C88.2 Gamma heavy chain disease
0.431 0.569 0.000
C88.1 Alpha heavy chain disease
0.431 0.569 0.000
E66 Obesity
0.000 0.571 0.429
M07.3 Other psoriatic arthropathies
0.424 0.576 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.576 0.424
E03.9 Hypothyroidism, unspecified
0.000 0.577 0.423
C84.4 Peripheral T-cell lymphoma
0.422 0.578 0.000
D52.8 Other folate deficiency anaemias
0.000 0.579 0.421
D52.1 Drug-induced folate deficiency anaemia
0.000 0.579 0.421
D52.0 Dietary folate deficiency anaemia
0.000 0.579 0.421
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.418 0.582 0.000
C83.0 Small cell (diffuse)
0.417 0.582 0.001
Chapter II Neoplasms
0.417 0.582 0.001
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.416 0.584 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.584 0.416
E20.8 Other hypoparathyroidism
0.000 0.584 0.416
E20.1 Pseudohypoparathyroidism
0.000 0.584 0.416
E20.0 Idiopathic hypoparathyroidism
0.000 0.584 0.416
E25.9 Adrenogenital disorder, unspecified
0.000 0.584 0.416
E25.8 Other adrenogenital disorders
0.000 0.584 0.416
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.584 0.416
E30.9 Disorder of puberty, unspecified
0.000 0.584 0.416
E30.8 Other disorders of puberty
0.000 0.584 0.416
E30.1 Precocious puberty
0.000 0.584 0.416
E30.0 Delayed puberty
0.000 0.584 0.416
E31.9 Polyglandular dysfunction, unspecified
0.000 0.584 0.416
E31.8 Other polyglandular dysfunction
0.000 0.584 0.416
E31.1 Polyglandular hyperfunction
0.000 0.584 0.416
E31.0 Autoimmune polyglandular failure
0.000 0.584 0.416
E32.9 Disease of thymus, unspecified
0.000 0.584 0.416
E32.8 Other diseases of thymus
0.000 0.584 0.416
E32.1 Abscess of thymus
0.000 0.584 0.416
E32.0 Persistent hyperplasia of thymus
0.000 0.584 0.416
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.584 0.416
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.584 0.416
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.584 0.416
C73 Malignant neoplasm of thyroid gland
0.416 0.584 0.000
D59 Acquired haemolytic anaemia
0.000 0.586 0.413
C84.5 Other and unspecified T-cell lymphomas
0.412 0.588 0.000
C92 Myeloid leukaemia
0.411 0.588 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.410 0.590 0.000
E14.4 With neurological complications
0.000 0.591 0.408
E21.3 Hyperparathyroidism, unspecified
0.000 0.597 0.403
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.598 0.402
E45 Retarded development following protein-energy malnutrition
0.000 0.598 0.402
E43 Unspecified severe protein-energy malnutrition
0.000 0.598 0.402
E42 Marasmic kwashiorkor
0.000 0.598 0.402
E41 Nutritional marasmus
0.000 0.598 0.402
E40 Kwashiorkor
0.000 0.598 0.402
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.598 0.402
E34.5 Androgen resistance syndrome
0.000 0.599 0.400
E34.4 Constitutional tall stature
0.000 0.599 0.400
E34.3 Short stature, not elsewhere classified
0.000 0.599 0.400
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.599 0.400
E34.1 Other hypersecretion of intestinal hormones
0.000 0.599 0.400
E67 Other hyperalimentation
0.000 0.601 0.399
E68 Sequelae of hyperalimentation
0.000 0.601 0.399
C91.5 Adult T-cell leukaemia
0.394 0.605 0.001
C95.9 Leukaemia, unspecified
0.394 0.606 0.000
D81.9 Combined immunodeficiency, unspecified
0.000 0.612 0.388
D81.8 Other combined immunodeficiencies
0.000 0.612 0.388
D81.7 Major histocompatibility complex class II deficiency
0.000 0.612 0.388
D81.6 Major histocompatibility complex class I deficiency
0.000 0.612 0.388
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.612 0.388
D81.4 Nezelof's syndrome
0.000 0.612 0.388
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.612 0.388
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.612 0.388
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.612 0.388
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.612 0.388
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.612 0.388
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.612 0.388
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.612 0.388
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.612 0.388
D82.2 Immunodeficiency with short-limbed stature
0.000 0.612 0.388
D82.1 Di George's syndrome
0.000 0.612 0.388
D82.0 Wiskott-Aldrich syndrome
0.000 0.612 0.388
C90.3 Solitary plasmacytoma
0.381 0.619 0.000
C90.1 Plasma cell leukaemia
0.381 0.619 0.000
D53.8 Other specified nutritional anaemias
0.000 0.620 0.379
D53.2 Scorbutic anaemia
0.000 0.620 0.379
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.620 0.379
D53.0 Protein deficiency anaemia
0.000 0.620 0.379
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.623 0.377
E28 Ovarian dysfunction
0.000 0.625 0.375
E50-E64 Other nutritional deficiencies
0.000 0.625 0.375
C91.9 Lymphoid leukaemia, unspecified
0.370 0.629 0.001
E34.8 Other specified endocrine disorders
0.000 0.630 0.369
M07.39 Other psoriatic arthropathies (Site unspecified)
0.367 0.633 0.000
J45 Asthma
0.000 0.633 0.366
C81.9 Hodgkin's disease, unspecified
0.364 0.635 0.000
M14 Arthropathies in other diseases classified elsewhere
0.364 0.636 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.363 0.637 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.359 0.641 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.358 0.641 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.358 0.642 0.000
M06.18 Adult-onset Still's disease (Other)
0.358 0.642 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.358 0.642 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.358 0.642 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.358 0.642 0.000
M06.14 Adult-onset Still's disease (Hand)
0.358 0.642 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.358 0.642 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.358 0.642 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.358 0.642 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.358 0.642 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.358 0.642 0.000
M06.28 Rheumatoid bursitis (Other)
0.358 0.642 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.358 0.642 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.358 0.642 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.358 0.642 0.000
M06.24 Rheumatoid bursitis (Hand)
0.358 0.642 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.358 0.642 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.358 0.642 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.358 0.642 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.358 0.642 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.358 0.642 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.358 0.642 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.358 0.642 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.358 0.642 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.358 0.642 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.358 0.642 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.358 0.642 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.358 0.642 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.358 0.642 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.358 0.642 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.642 0.357
E00 Congenital iodine-deficiency syndrome
0.000 0.642 0.357
D53.9 Nutritional anaemia, unspecified
0.000 0.643 0.357
M12 Other specific arthropathies
0.355 0.645 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.355 0.645 0.000
M08 Juvenile arthritis
0.355 0.645 0.000
D57 Sickle-cell disorders
0.000 0.645 0.355
D55 Anaemia due to enzyme disorders
0.000 0.645 0.355
E46 Unspecified protein-energy malnutrition
0.000 0.645 0.355
D59.1 Other autoimmune haemolytic anaemias
0.000 0.647 0.353
C43 Malignant melanoma of skin
0.352 0.648 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.649 0.351
C88.0 Waldenstrom's macroglobulinaemia
0.350 0.649 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.349 0.651 0.000
M06.38 Rheumatoid nodule (Other)
0.349 0.651 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.349 0.651 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.349 0.651 0.000
M06.33 Rheumatoid nodule (Forearm)
0.349 0.651 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.349 0.651 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.349 0.651 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.653 0.347
E29.8 Other testicular dysfunction
0.000 0.653 0.347
E29.0 Testicular hyperfunction
0.000 0.653 0.347
M06.34 Rheumatoid nodule (Hand)
0.346 0.654 0.000
M11 Other crystal arthropathies
0.344 0.656 0.000
E66.9 Obesity, unspecified
0.000 0.659 0.341
M07.30 Other psoriatic arthropathies (Multiple sites)
0.341 0.659 0.000
E26 Hyperaldosteronism
0.002 0.660 0.338
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.339 0.661 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.339 0.661 0.000
D83.8 Other common variable immunodeficiencies
0.000 0.661 0.338
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.661 0.338
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.661 0.338
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.661 0.338
M06.48 Inflammatory polyarthropathy (Other)
0.337 0.662 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.337 0.662 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.337 0.662 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.337 0.662 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.337 0.662 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.337 0.662 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.337 0.662 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.337 0.662 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.333 0.667 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.332 0.668 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.331 0.669 0.000
E27.9 Disorder of adrenal gland, unspecified
0.001 0.669 0.330
C91.8 Mature B-cell leukaemia Burkitt-type
0.330 0.669 0.001
C91.7 Other lymphoid leukaemia
0.330 0.669 0.001
C91.6 Prolymphocytic leukaemia of T-cell type
0.330 0.669 0.001
C91.3 Prolymphocytic leukaemia
0.330 0.669 0.001
C91.2 Subacute lymphocytic leukaemia
0.330 0.669 0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.669 0.330
C90.0 Multiple myeloma
0.330 0.670 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.329 0.671 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.329 0.671 0.000
E66.8 Other obesity
0.000 0.671 0.329
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.673 0.327
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.673 0.327
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.673 0.327
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.673 0.327
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.673 0.327
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.673 0.327
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.673 0.327
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.673 0.327
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.327 0.673 0.000
C74 Malignant neoplasm of adrenal gland
0.326 0.673 0.000
M07.6 Other enteropathic arthropathies
0.325 0.675 0.000
M07.5 Arthropathy in ulcerative colitis
0.325 0.675 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.325 0.675 0.000
M07.2 Psoriatic spondylitis
0.325 0.675 0.000
M07.1 Arthritis mutilans
0.325 0.675 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.325 0.675 0.000
E03.5 Myxoedema coma
0.000 0.676 0.324
E03.4 Atrophy of thyroid (acquired)
0.000 0.676 0.324
E03.3 Postinfectious hypothyroidism
0.000 0.676 0.324
E03.1 Congenital hypothyroidism without goitre
0.000 0.676 0.324
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.676 0.324
M05.8 Other seropositive rheumatoid arthritis
0.319 0.680 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.319 0.680 0.000
M05.2 Rheumatoid vasculitis
0.319 0.680 0.000
M05.1 Rheumatoid lung disease
0.319 0.680 0.000
M05.0 Felty's syndrome
0.319 0.680 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.682 0.318
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.317 0.683 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.314 0.686 0.000
D84.8 Other specified immunodeficiencies
0.001 0.687 0.312
D84.1 Defects in the complement system
0.001 0.687 0.312
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.001 0.687 0.312
E34.9 Endocrine disorder, unspecified
0.000 0.689 0.310

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.