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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16870880
log Bayes Factor = 5.92331
Chromosome 6   position 32,782,018  (GRCh37) Explore rs16870880 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.097 0.903
E10.9 Without complications
0.000 0.098 0.902
E10-E14 Diabetes mellitus
0.000 0.117 0.883
E11 Non-insulin-dependent diabetes mellitus
0.000 0.120 0.880
E11.4 With neurological complications
0.000 0.148 0.852
E11.3 With ophthalmic complications
0.000 0.185 0.815
E10.3 With ophthalmic complications
0.000 0.192 0.808
E10.1 With ketoacidosis
0.000 0.196 0.804
E11.5 With peripheral circulatory complications
0.000 0.243 0.757
E10.4 With neurological complications
0.000 0.273 0.727
E11.1 With ketoacidosis
0.000 0.274 0.726
E11.6 With other specified complications
0.000 0.289 0.711
E11.0 With coma
0.000 0.300 0.700
E10.5 With peripheral circulatory complications
0.000 0.306 0.694
E14 Unspecified diabetes mellitus
0.000 0.314 0.686
E10.2 With renal complications
0.000 0.338 0.662
E10.8 With unspecified complications
0.000 0.353 0.647
E10.7 With multiple complications
0.000 0.353 0.647
E10.6 With other specified complications
0.000 0.353 0.647
E10.0 With coma
0.000 0.353 0.647
E12 Malnutrition-related diabetes mellitus
0.000 0.367 0.633
E11.8 With unspecified complications
0.000 0.369 0.631
E11.7 With multiple complications
0.000 0.369 0.631
E14.3 With ophthalmic complications
0.000 0.391 0.609
E13 Other specified diabetes mellitus
0.000 0.423 0.577
E11.2 With renal complications
0.000 0.481 0.519
E14.8 With unspecified complications
0.000 0.508 0.492
E14.7 With multiple complications
0.000 0.508 0.492
E14.6 With other specified complications
0.000 0.508 0.492
E14.5 With peripheral circulatory complications
0.000 0.508 0.492
E14.4 With neurological complications
0.000 0.508 0.492
E14.2 Withrenal complications
0.000 0.508 0.492
E14.1 With ketoacidosis
0.000 0.508 0.492
E14.0 With coma
0.000 0.508 0.492
E12.9 Without complications
0.000 0.546 0.454
E12.8 With unspecified complications
0.000 0.546 0.454
E12.7 With multiple complications
0.000 0.546 0.454
E12.6 With other specified complications
0.000 0.546 0.454
E12.5 With peripheral circulatory complications
0.000 0.546 0.454
E12.4 With neurological complications
0.000 0.546 0.454
E12.3 With ophthalmic complications
0.000 0.546 0.454
E12.2 With renal complications
0.000 0.546 0.454
E12.1 With ketoacidosis
0.000 0.546 0.454
E12.0 With coma
0.000 0.546 0.454
E13.8 With unspecified complications
0.000 0.586 0.414
E13.7 With multiple complications
0.000 0.586 0.414
E13.6 With other specified complications
0.000 0.586 0.414
E13.5 With peripheral circulatory complications
0.000 0.586 0.414
E13.4 With neurological complications
0.000 0.586 0.414
E13.3 With ophthalmic complications
0.000 0.586 0.414
E13.2 With renal complications
0.000 0.586 0.414
E13.1 With ketoacidosis
0.000 0.586 0.414
E13.0 With coma
0.000 0.586 0.414
K90 Intestinal malabsorption
0.000 0.597 0.402
E11.9 Without complications
0.000 0.599 0.401
E13.9 Without complications
0.000 0.642 0.358
E14.9 Without complications
0.000 0.671 0.329
K90.9 Intestinal malabsorption, unspecified
0.000 0.688 0.311
K90.3 Pancreatic steatorrhoea
0.000 0.711 0.289
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.711 0.289
K90.1 Tropical sprue
0.000 0.711 0.289
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.727 0.273
K90.8 Other intestinal malabsorption
0.001 0.788 0.212
K90-K93 Other diseases of the digestive system
0.000 0.879 0.121
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.906 0.094
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.913 0.087
K91.4 Colostomy and enterostomy malfunction
0.000 0.913 0.087
K91.3 Postoperative intestinal obstruction
0.000 0.924 0.076
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.932 0.068
K91.5 Postcholecystectomy syndrome
0.000 0.932 0.068
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.932 0.068
K91.1 Postgastric surgery syndromes
0.000 0.932 0.068
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.937 0.062
K93.1 Megacolon in Chagas' disease
0.000 0.937 0.062
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.937 0.062
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.938 0.061
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.939 0.061
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.947 0.053
K92 Other diseases of digestive system
0.000 0.952 0.048
E16 Other disorders of pancreatic internal secretion
0.000 0.953 0.047
E16.2 Hypoglycaemia, unspecified
0.000 0.956 0.043
E40-E46 Malnutrition
0.000 0.957 0.043
E00-E07 Disorders of thyroid gland
0.000 0.957 0.043
E03 Other hypothyroidism
0.000 0.959 0.041
K92.1 Melaena
0.000 0.960 0.040
E03.9 Hypothyroidism, unspecified
0.000 0.961 0.039
K92.8 Other specified diseases of digestive system
0.000 0.962 0.038
E15 Nondiabetic hypoglycaemic coma
0.000 0.962 0.038
E50-E64 Other nutritional deficiencies
0.000 0.962 0.037
E06 Thyroiditis
0.000 0.965 0.035
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.966 0.034
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.966 0.034
E16.4 Abnormal secretion of gastrin
0.000 0.966 0.034
E16.3 Increased secretion of glucagon
0.000 0.966 0.034
E16.1 Other hypoglycaemia
0.000 0.966 0.034
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.966 0.034
E55 Vitamin D deficiency
0.000 0.968 0.032
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.969 0.031
E45 Retarded development following protein-energy malnutrition
0.000 0.969 0.031
E43 Unspecified severe protein-energy malnutrition
0.000 0.969 0.031
E42 Marasmic kwashiorkor
0.000 0.969 0.031
E41 Nutritional marasmus
0.000 0.969 0.031
E40 Kwashiorkor
0.000 0.969 0.031
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.969 0.031
E00 Congenital iodine-deficiency syndrome
0.000 0.969 0.031
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.969 0.031
E46 Unspecified protein-energy malnutrition
0.000 0.969 0.031
E03.8 Other specified hypothyroidism
0.000 0.969 0.031
E06.3 Autoimmune thyroiditis
0.000 0.970 0.029
E03.5 Myxoedema coma
0.000 0.971 0.029
E03.4 Atrophy of thyroid (acquired)
0.000 0.971 0.029
E03.3 Postinfectious hypothyroidism
0.000 0.971 0.029
E03.1 Congenital hypothyroidism without goitre
0.000 0.971 0.029
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.971 0.029
E65-E68 Obesity and other hyperalimentation
0.000 0.971 0.028
E55.9 Vitamin D deficiency, unspecified
0.000 0.972 0.028
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.973 0.027
E63 Other nutritional deficiencies
0.000 0.973 0.027
E56 Other vitamin deficiencies
0.000 0.973 0.027
E51 Thiamine deficiency
0.000 0.973 0.027
E50 Vitamin A deficiency
0.000 0.973 0.027
E60 Dietary zinc deficiency
0.000 0.973 0.027
E59 Dietary selenium deficiency
0.000 0.973 0.027
E58 Dietary calcium deficiency
0.000 0.973 0.027
E54 Ascorbic acid deficiency
0.000 0.973 0.027
E52 Niacin deficiency [pellagra]
0.000 0.973 0.027
K92.9 Disease of digestive system, unspecified
0.000 0.973 0.027
K92.0 Haematemesis
0.000 0.973 0.027
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.974 0.026
E06.9 Thyroiditis, unspecified
0.000 0.974 0.025
E06.5 Other chronic thyroiditis
0.000 0.974 0.025
E06.4 Drug-induced thyroiditis
0.000 0.974 0.025
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.974 0.025
E06.1 Subacute thyroiditis
0.000 0.974 0.025
E06.0 Acute thyroiditis
0.000 0.974 0.025
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.975 0.025
E07 Other disorders of thyroid
0.000 0.975 0.025
E20-E35 Disorders of other endocrine glands
0.000 0.976 0.023
E55.0 Rickets, active
0.000 0.977 0.023
E44.1 Mild protein-energy malnutrition
0.000 0.977 0.023
E44.0 Moderate protein-energy malnutrition
0.000 0.977 0.023
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.977 0.023
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.977 0.023
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.977 0.023
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.977 0.023
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.977 0.023
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.977 0.023
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.977 0.023
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.977 0.023
G47.9 Sleep disorder, unspecified
0.022 0.978 0.000
H36.0 Diabetic retinopathy
0.000 0.978 0.022
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.979 0.021
E67 Other hyperalimentation
0.000 0.979 0.021
E68 Sequelae of hyperalimentation
0.000 0.979 0.021
E61 Deficiency of other nutrient elements
0.000 0.980 0.020
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.020 0.980 0.000
E27 Other disorders of adrenal gland
0.000 0.980 0.020
E53 Deficiency of other B group vitamins
0.000 0.980 0.020
E50.9 Vitamin A deficiency, unspecified
0.000 0.980 0.019
E50.8 Other manifestations of vitamin A deficiency
0.000 0.980 0.019
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.980 0.019
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.980 0.019
E50.5 Vitamin A deficiency with night blindness
0.000 0.980 0.019
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.980 0.019
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.980 0.019
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.980 0.019
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.980 0.019
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.980 0.019
E51.9 Thiamine deficiency, unspecified
0.000 0.980 0.019
E51.8 Other manifestations of thiamine deficiency
0.000 0.980 0.019
E51.2 Wernicke's encephalopathy
0.000 0.980 0.019
E51.1 Beriberi
0.000 0.980 0.019
E56.9 Vitamin deficiency, unspecified
0.000 0.980 0.019
E56.8 Deficiency of other vitamins
0.000 0.980 0.019
E56.1 Deficiency of vitamin K
0.000 0.980 0.019
E56.0 Deficiency of vitamin E
0.000 0.980 0.019
E63.9 Nutritional deficiency, unspecified
0.000 0.980 0.019
E63.8 Other specified nutritional deficiencies
0.000 0.980 0.019
E63.1 Imbalance of constituents of food intake
0.000 0.980 0.019
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.980 0.019
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.980 0.019
E64.8 Sequelae of other nutritional deficiencies
0.000 0.980 0.019
E64.3 Sequelae of rickets
0.000 0.980 0.019
E64.2 Sequelae of vitamin C deficiency
0.000 0.980 0.019
E64.1 Sequelae of vitamin A deficiency
0.000 0.980 0.019
E64.0 Sequelae of protein-energy malnutrition
0.000 0.980 0.019
E65 Localised adiposity
0.000 0.981 0.019
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.001 0.981 0.019
Z42.1 Follow-up care involving plastic surgery of breast
0.000 0.981 0.019
M23.2 Derangement of meniscus due to old tear or injury
0.019 0.981 0.000
E05.8 Other thyrotoxicosis
0.000 0.982 0.018
E05.5 Thyroid crisis or storm
0.000 0.982 0.018
E05.4 Thyrotoxicosis factitia
0.000 0.982 0.018
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.982 0.018
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.982 0.018
E07.1 Dyshormogenetic goitre
0.000 0.982 0.018
E07.0 Hypersecretion of calcitonin
0.000 0.982 0.018
M23 Internal derangement of knee
0.018 0.982 0.000
E29 Testicular dysfunction
0.000 0.982 0.018
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.018 0.982 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.983 0.017
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.983 0.017
E32 Diseases of thymus
0.000 0.983 0.017
E31 Polyglandular dysfunction
0.000 0.983 0.017
E30 Disorders of puberty, not elsewhere classified
0.000 0.983 0.017
E26 Hyperaldosteronism
0.000 0.983 0.017
E25 Adrenogenital disorders
0.000 0.983 0.017
E20 Hypoparathyroidism
0.000 0.983 0.017
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.983 0.017
E24 Cushing's syndrome
0.000 0.983 0.016
M23.4 Loose body in knee
0.016 0.984 0.000
E07.8 Other specified disorders of thyroid
0.000 0.984 0.016
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.016 0.984 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.015 0.985 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.985 0.015
E67.8 Other specified hyperalimentation
0.000 0.985 0.015
E67.3 Hypervitaminosis D
0.000 0.985 0.015
E67.2 Megavitamin-B6 syndrome
0.000 0.985 0.015
E67.1 Hypercarotenaemia
0.000 0.985 0.015
E67.0 Hypervitaminosis A
0.000 0.985 0.015
E34 Other endocrine disorders
0.000 0.985 0.015
E61.9 Deficiency of nutrient element, unspecified
0.000 0.985 0.014
E61.8 Deficiency of other specified nutrient elements
0.000 0.985 0.014
E61.7 Deficiency of multiple nutrient elements
0.000 0.985 0.014
E61.6 Vanadium deficiency
0.000 0.985 0.014
E61.5 Molybdenum deficiency
0.000 0.985 0.014
E61.4 Chromium deficiency
0.000 0.985 0.014
E61.3 Manganese deficiency
0.000 0.985 0.014
E61.0 Copper deficiency
0.000 0.985 0.014
M23.3 Other meniscus derangements
0.015 0.985 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.985 0.014
E27.5 Adrenomedullary hyperfunction
0.000 0.985 0.014
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.985 0.014
E27.0 Other adrenocortical overactivity
0.000 0.985 0.014
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.015 0.985 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.985 0.014
E53.1 Pyridoxine deficiency
0.000 0.985 0.014
E53.0 Riboflavin deficiency
0.000 0.985 0.014
E07.9 Disorder of thyroid, unspecified
0.000 0.986 0.014
M23.9 Internal derangement of knee, unspecified
0.014 0.986 0.000
M23.5 Chronic instability of knee
0.014 0.986 0.000
M23.40 Loose body in knee-Mult sites
0.014 0.986 0.000
E27.2 Addisonian crisis
0.000 0.986 0.014
Z42 Follow-up care involving plastic surgery
0.000 0.986 0.014
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.986 0.014
E23 Hypofunction and other disorders of pituitary gland
0.000 0.986 0.014
M23.0 Cystic meniscus
0.014 0.986 0.000
E04 Other non-toxic goitre
0.000 0.986 0.014
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.014 0.986 0.000
M23.41 Loose body in knee-Ant lig/hrn men
0.014 0.986 0.000
M23.8 Other internal derangements of knee
0.014 0.986 0.000
M23.46 Loose body in knee-O/unsp lat men
0.013 0.987 0.000
E29.1 Testicular hypofunction
0.000 0.987 0.013
E28 Ovarian dysfunction
0.000 0.987 0.013
E05.9 Thyrotoxicosis, unspecified
0.000 0.987 0.013
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.013 0.987 0.000
E61.2 Magnesium deficiency
0.000 0.987 0.013
M23.1 Discoid meniscus (congenital)
0.013 0.987 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.987 0.013
E29.8 Other testicular dysfunction
0.000 0.987 0.013
E29.0 Testicular hyperfunction
0.000 0.987 0.013
Z42.0 Follow-up care involving plastic surgery of head and neck
0.000 0.987 0.013
E21.0 Primary hyperparathyroidism
0.000 0.987 0.013
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.013 0.987 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.987 0.012
E20.8 Other hypoparathyroidism
0.000 0.987 0.012
E20.1 Pseudohypoparathyroidism
0.000 0.987 0.012
E20.0 Idiopathic hypoparathyroidism
0.000 0.987 0.012
E25.9 Adrenogenital disorder, unspecified
0.000 0.987 0.012
E25.8 Other adrenogenital disorders
0.000 0.987 0.012
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.987 0.012
E26.9 Hyperaldosteronism, unspecified
0.000 0.987 0.012
E26.8 Other hyperaldosteronism
0.000 0.987 0.012
E26.1 Secondary hyperaldosteronism
0.000 0.987 0.012
E26.0 Primary hyperaldosteronism
0.000 0.987 0.012
E30.9 Disorder of puberty, unspecified
0.000 0.987 0.012
E30.8 Other disorders of puberty
0.000 0.987 0.012
E30.1 Precocious puberty
0.000 0.987 0.012
E30.0 Delayed puberty
0.000 0.987 0.012
E31.9 Polyglandular dysfunction, unspecified
0.000 0.987 0.012
E31.8 Other polyglandular dysfunction
0.000 0.987 0.012
E31.1 Polyglandular hyperfunction
0.000 0.987 0.012
E31.0 Autoimmune polyglandular failure
0.000 0.987 0.012
E32.9 Disease of thymus, unspecified
0.000 0.987 0.012
E32.8 Other diseases of thymus
0.000 0.987 0.012
E32.1 Abscess of thymus
0.000 0.987 0.012
E32.0 Persistent hyperplasia of thymus
0.000 0.987 0.012
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.987 0.012
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.987 0.012
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.987 0.012
M23.6 Other spontaneous disruption of ligament(s) of knee
0.012 0.988 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.988 0.012
E24.8 Other Cushing's syndrome
0.000 0.988 0.012
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.988 0.012
E24.3 Ectopic ACTH syndrome
0.000 0.988 0.012
E24.2 Drug-induced Cushing's syndrome
0.000 0.988 0.012
E24.1 Nelson's syndrome
0.000 0.988 0.012
E24.0 Pituitary-dependent Cushing's disease
0.000 0.988 0.012
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.012 0.988 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.000 0.988 0.012
M23.47 Loose body in knee-Capsular lig
0.012 0.988 0.000
M23.45 Loose body in knee-Pst hrn lat men
0.012 0.988 0.000
M23.44 Loose body in knee-Lat lig/ant men
0.012 0.988 0.000
M23.43 Loose body in knee-Med lig/oth men
0.012 0.988 0.000
M23.42 Loose body in knee-Pst lig/hrn men
0.012 0.988 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.012 0.988 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.012 0.988 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.988 0.011
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.000 0.988 0.011
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)
0.011 0.989 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.011 0.989 0.000
K66.0 Peritoneal adhesions
0.000 0.989 0.011
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.011 0.989 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.989 0.011
E21.4 Other specified disorders of parathyroid gland
0.000 0.989 0.011
E21.2 Other hyperparathyroidism
0.000 0.989 0.011
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)
0.011 0.989 0.000
E22 Hyperfunction of pituitary gland
0.000 0.989 0.011
E34.8 Other specified endocrine disorders
0.000 0.989 0.011
E34.5 Androgen resistance syndrome
0.000 0.989 0.011
E34.4 Constitutional tall stature
0.000 0.989 0.011
E34.3 Short stature, not elsewhere classified
0.000 0.989 0.011
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.989 0.011
E34.1 Other hypersecretion of intestinal hormones
0.000 0.989 0.011
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.011 0.989 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.989 0.011
M23.37 Other meniscus derangements-Capsular lig
0.011 0.989 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.011 0.989 0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)
0.010 0.989 0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)
0.010 0.989 0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)
0.010 0.989 0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.010 0.989 0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)
0.010 0.989 0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.010 0.989 0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.010 0.989 0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)
0.010 0.989 0.000
M23.57 Chronic instability of knee (Capsular ligament)
0.010 0.989 0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)
0.010 0.989 0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)
0.010 0.989 0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.010 0.989 0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.010 0.989 0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.010 0.989 0.000
M23.50 Chronic instability of knee (Multiple sites)
0.010 0.989 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.010 0.989 0.000
M23.49 Loose body in knee-Unspec lig/men
0.010 0.989 0.000
E23.2 Diabetes insipidus
0.000 0.989 0.010
E34.0 Carcinoid syndrome
0.000 0.989 0.010
E61.1 Iron deficiency
0.000 0.990 0.010
Z42.9 Follow-up care involving plastic surgery, unspecified
0.000 0.990 0.010
Z42.8 Follow-up care involving plastic surgery of other body part
0.000 0.990 0.010
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.010 0.990 0.000
E23.6 Other disorders of pituitary gland
0.000 0.990 0.010
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.990 0.010
E23.1 Drug-induced hypopituitarism
0.000 0.990 0.010
M23.80 Other internal derangements of knee (Multiple sites)
0.010 0.990 0.000
E04.8 Other specified non-toxic goitre
0.000 0.990 0.010
M23.07 Cystic meniscus-Capsular lig
0.010 0.990 0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)
0.010 0.990 0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.010 0.990 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.010 0.990 0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.010 0.990 0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.010 0.990 0.000
M23.00 Cystic meniscus (Multiple sites)
0.010 0.990 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.010 0.990 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.990 0.010
M23.87 Other internal derangements of knee (Capsular ligament)
0.010 0.990 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.010 0.990 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.010 0.990 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.010 0.990 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.990 0.010
E28.8 Other ovarian dysfunction
0.000 0.990 0.010
E28.1 Androgen excess
0.000 0.990 0.010
E28.0 Oestrogen excess
0.000 0.990 0.010
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.010 0.990 0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)
0.009 0.990 0.000
M23.17 Discoid meniscus (congenital)-Capsular lig
0.009 0.990 0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.009 0.990 0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)
0.009 0.990 0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.009 0.990 0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)
0.009 0.990 0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.009 0.990 0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.009 0.990 0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)
0.009 0.990 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.009 0.990 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.990 0.010
E34.9 Endocrine disorder, unspecified
0.000 0.990 0.009
E04.9 Non-toxic goitre, unspecified
0.000 0.991 0.009
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.009 0.991 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.000 0.991 0.009
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)
0.009 0.991 0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)
0.009 0.991 0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp
0.009 0.991 0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn
0.009 0.991 0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.009 0.991 0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.009 0.991 0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.009 0.991 0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)
0.009 0.991 0.000
E28.3 Primary ovarian failure
0.000 0.991 0.009
E04.0 Non-toxic diffuse goitre
0.000 0.991 0.009
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.009 0.991 0.000
E66 Obesity
0.000 0.991 0.009
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.008 0.991 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.008 0.991 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.992 0.008
E22.8 Other hyperfunction of pituitary gland
0.000 0.992 0.008
G40 Epilepsy
0.008 0.992 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.008 0.992 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.008 0.992 0.000
E23.0 Hypopituitarism
0.000 0.992 0.007
M22 Disorders of patella
0.007 0.993 0.000
G40.8 Other epilepsy
0.007 0.993 0.000
E22.1 Hyperprolactinaemia
0.000 0.993 0.007
E53.8 Deficiency of other specified B group vitamins
0.000 0.993 0.007
G47 Sleep disorders
0.007 0.993 0.000
M20-M25 Other joint disorders
0.007 0.993 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.993 0.007
E28.2 Polycystic ovarian syndrome
0.000 0.993 0.007
E04.1 Non-toxic single thyroid nodule
0.000 0.993 0.007
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.993 0.007
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.007 0.993 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.007 0.993 0.000
M22.2 Patellofemoral disorders
0.007 0.993 0.000
G40.5 Special epileptic syndromes
0.006 0.993 0.000
E66.0 Obesity due to excess calories
0.000 0.993 0.006
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.006 0.994 0.000
M22.4 Chondromalacia patellae
0.006 0.994 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.994 0.006
E66.1 Drug-induced obesity
0.000 0.994 0.006
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.006 0.994 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.994 0.006
E22.0 Acromegaly and pituitary gigantism
0.001 0.994 0.006
G40.7 Petit mal, unspecified, without grand mal seizures
0.006 0.994 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.006 0.994 0.000
G47.4 Narcolepsy and cataplexy
0.006 0.994 0.000
M22.8 Other disorders of patella
0.006 0.994 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.994 0.006
M20.5 Other deformities of toe(s) (acquired)
0.006 0.994 0.000
M22.3 Other derangements of patella
0.006 0.994 0.000
M32 Systemic lupus erythematosus
0.006 0.994 0.000
M30 Polyarteritis nodosa and related conditions
0.006 0.994 0.000
M33 Dermatopolymyositis
0.006 0.994 0.000
M21 Other acquired deformities of limbs
0.006 0.994 0.000
M22.1 Recurrent subluxation of patella
0.005 0.994 0.000
M22.9 Disorder of patella, unspecified
0.005 0.994 0.000
M22.0 Recurrent dislocation of patella
0.005 0.994 0.000
M35 Other systemic involvement of connective tissue
0.005 0.994 0.000
G40-G47 Episodic and paroxysmal disorders
0.006 0.994 0.000
G47.2 Disorders of the sleep-wake schedule
0.005 0.995 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.005 0.995 0.000
M50.3 Other cervical disk degeneration
0.005 0.995 0.000
M50.1 Cervical disk disorder with radiculopathy
0.005 0.995 0.000
M50 Cervical disk disorders
0.005 0.995 0.000
M35.0 Sicca syndrome [Sjogren]
0.005 0.995 0.000
M34 Systemic sclerosis
0.005 0.995 0.000
M21.1 Varus deformity, not elsewhere classified
0.005 0.995 0.000
M50.2 Other cervical disk displacement
0.005 0.995 0.000
G47.8 Other sleep disorders
0.005 0.995 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.005 0.995 0.000
M30.0 Polyarteritis nodosa
0.005 0.995 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.005 0.995 0.000
M50.9 Cervical disk disorder, unspecified
0.005 0.995 0.000
R27.0 Ataxia, unspecified
0.005 0.995 0.000
M33.2 Polymyositis
0.004 0.995 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.005 0.995 0.000
G40.9 Epilepsy, unspecified
0.005 0.995 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.005 0.995 0.000
G41 Status epilepticus
0.005 0.995 0.000
M33.1 Other dermatomyositis
0.004 0.995 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.000 0.995 0.005
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.004 0.996 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.004 0.996 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.004 0.996 0.000
M32.8 Other forms of systemic lupus erythematosus
0.004 0.996 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.004 0.996 0.000
M31 Other necrotising vasculopathies
0.004 0.996 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.004 0.996 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.004 0.996 0.000
M30.2 Juvenile polyarteritis
0.004 0.996 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.004 0.996 0.000
M33.9 Dermatopolymyositis, unspecified
0.004 0.996 0.000
M33.0 Juvenile dermatomyositis
0.004 0.996 0.000
M24 Other specific joint derangements
0.004 0.996 0.000
M21.9 Acquired deformity of limb, unspecified
0.004 0.996 0.000
M21.8 Other specified acquired deformities of limbs
0.004 0.996 0.000
M21.7 Unequal limb length (acquired)
0.004 0.996 0.000
M21.4 Flat foot [pes planus] (acquired)
0.004 0.996 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.000 0.996 0.004
M22.10 Recurrent subluxation of patella, unspecified knee
0.004 0.996 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.004 0.996 0.000
M35.8 Other specified systemic involvement of connective tissue
0.004 0.996 0.000
M35.7 Hypermobility syndrome
0.004 0.996 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.004 0.996 0.000
M35.5 Multifocal fibrosclerosis
0.004 0.996 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.004 0.996 0.000
M35.2 Behcet's disease
0.004 0.996 0.000
M35.1 Other overlap syndromes
0.004 0.996 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.004 0.996 0.000
M21.3 Wrist or foot drop (acquired)
0.004 0.996 0.000
M34.8 Other forms of systemic sclerosis
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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