TreeWAS – Variant ID: rs16875255

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I49 Other cardiac arrhythmias	0.000	0.957	0.043
I49.4 Other and unspecified premature depolarisation	0.000	0.957	0.043
I49.0 Ventricular fibrillation and flutter	0.000	0.958	0.042
I44.2 Atrioventricular block, complete	0.000	0.959	0.041
I49.5 Sick sinus syndrome	0.000	0.959	0.041
I35 Nonrheumatic aortic valve disorders	0.000	0.963	0.037
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.964	0.036
I49.9 Cardiac arrhythmia, unspecified	0.000	0.964	0.036
I44 Atrioventricular and left bundle-branch block	0.000	0.965	0.035
I35.0 Aortic (valve) stenosis	0.000	0.965	0.035
I30-I52 Other forms of heart disease	0.000	0.967	0.033
I44.0 Atrioventricular block, first degree	0.000	0.967	0.033
I35.1 Aortic (valve) insufficiency	0.000	0.968	0.032
I49.3 Ventricular premature depolarisation	0.000	0.969	0.031
I49.2 Junctional premature depolarisation	0.000	0.969	0.031
I47.2 Ventricular tachycardia	0.000	0.970	0.030
I45 Other conduction disorders	0.000	0.971	0.029
I35.9 Aortic valve disorder, unspecified	0.000	0.971	0.029
I42 Cardiomyopathy	0.000	0.971	0.029
I47 Paroxysmal tachycardia	0.000	0.971	0.029
I49.1 Atrial premature depolarisation	0.000	0.973	0.027
I44.3 Other and unspecified atrioventricular block	0.000	0.974	0.026
I44.5 Left posterior fascicular block	0.000	0.974	0.026
I44.4 Left anterior fascicular block	0.000	0.974	0.026
I45.9 Conduction disorder, unspecified	0.000	0.975	0.025
I42.9 Cardiomyopathy, unspecified	0.000	0.975	0.025
I42.2 Other hypertrophic cardiomyopathy	0.000	0.975	0.024
I45.3 Trifascicular block	0.000	0.976	0.024
I52 Other heart disorders in diseases classified elsewhere	0.000	0.976	0.024
I48 Atrial fibrillation and flutter	0.000	0.976	0.024
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.976	0.024
I41 Myocarditis in diseases classified elsewhere	0.000	0.976	0.024
I40 Acute myocarditis	0.000	0.976	0.024
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.976	0.024
I32 Pericarditis in diseases classified elsewhere	0.000	0.976	0.024
I45.1 Other and unspecified right bundle-branch block	0.000	0.976	0.024
I35.8 Other aortic valve disorders	0.000	0.976	0.023
I42.0 Dilated cardiomyopathy	0.000	0.977	0.023
I37 Pulmonary valve disorders	0.000	0.977	0.023
I45.4 Nonspecific intraventricular block	0.000	0.977	0.022
I45.5 Other specified heart block	0.000	0.978	0.022
I45.6 Preexcitation syndrome	0.000	0.978	0.022
I45.0 Right fascicular block	0.000	0.979	0.021
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.979	0.021
I42.6 Alcoholic cardiomyopathy	0.000	0.979	0.021
I42.5 Other restrictive cardiomyopathy	0.000	0.979	0.021
I42.4 Endocardial fibroelastosis	0.000	0.979	0.021
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.979	0.021
I36 Nonrheumatic tricuspid valve disorders	0.000	0.979	0.021
I47.0 Reentry ventricular arrhythmia	0.000	0.979	0.021
I33 Acute and subacute endocarditis	0.000	0.979	0.021
I44.6 Other and unspecified fascicular block	0.000	0.980	0.020
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.980	0.020
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.980	0.019
I30 Acute pericarditis	0.000	0.981	0.019
I42.8 Other cardiomyopathies	0.000	0.981	0.019
I44.7 Left bundle-branch block, unspecified	0.000	0.982	0.018
I45.8 Other specified conduction disorders	0.000	0.982	0.018
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.982	0.017
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.982	0.017
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.982	0.017
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.982	0.017
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.982	0.017
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.982	0.017
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.982	0.017
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.982	0.017
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.982	0.017
I40.9 Acute myocarditis, unspecified	0.000	0.982	0.017
I40.8 Other acute myocarditis	0.000	0.982	0.017
I40.1 Isolated myocarditis	0.000	0.982	0.017
I40.0 Infective myocarditis	0.000	0.982	0.017
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.982	0.017
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.982	0.017
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.982	0.017
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.982	0.017
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.982	0.017
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.982	0.017
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.982	0.017
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.982	0.017
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.982	0.017
I48.4 Atypical atrial flutter	0.000	0.982	0.017
I48.3 Typical atrial flutter	0.000	0.982	0.017
I48.2 Chronic atrial fibrillation	0.000	0.982	0.017
I48.1 Persistent atrial fibrillation	0.000	0.982	0.017
I48.0 Paroxysmal atrial fibrillation	0.000	0.982	0.017
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.982	0.017
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.982	0.017
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.982	0.017
I49.8 Other specified cardiac arrhythmias	0.000	0.983	0.017
I45.2 Bifascicular block	0.000	0.983	0.017
I37.9 Pulmonary valve disorder, unspecified	0.000	0.983	0.017
I37.8 Other pulmonary valve disorders	0.000	0.983	0.017
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.983	0.017
I37.0 Pulmonary valve stenosis	0.000	0.983	0.017
I44.1 Atrioventricular block, second degree	0.000	0.983	0.017
I37.1 Pulmonary valve insufficiency	0.000	0.984	0.016
I31 Other diseases of pericardium	0.000	0.984	0.016
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.985	0.015
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.985	0.015
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.985	0.015
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.985	0.015
I33.9 Acute endocarditis, unspecified	0.000	0.985	0.015
I46 Cardiac arrest	0.000	0.986	0.014
I30.8 Other forms of acute pericarditis	0.000	0.986	0.014
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.986	0.014
I30.9 Acute pericarditis, unspecified	0.000	0.987	0.013
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.988	0.012
I31.8 Other specified diseases of pericardium	0.000	0.988	0.012
I31.2 Haemopericardium, not elsewhere classified	0.000	0.988	0.012
I31.0 Chronic adhesive pericarditis	0.000	0.988	0.012
I33.0 Acute and subacute infective endocarditis	0.000	0.988	0.011
I31.1 Chronic constrictive pericarditis	0.000	0.989	0.010
I30.1 Infective pericarditis	0.000	0.990	0.010
I46.1 Sudden cardiac death, so described	0.000	0.990	0.010
R00.1 Bradycardia, unspecified	0.000	0.991	0.009
I31.9 Disease of pericardium, unspecified	0.000	0.991	0.009
I31.3 Pericardial effusion (noninflammatory)	0.000	0.991	0.009
I34 Nonrheumatic mitral valve disorders	0.000	0.991	0.009
I46.9 Cardiac arrest, unspecified	0.000	0.991	0.009
S92.00 Fracture of calcaneus (closed)	0.009	0.991	0.000
I38 Endocarditis, valve unspecified	0.001	0.992	0.008
S01.5 Open wound of lip and oral cavity	0.000	0.992	0.008
S01.1 Open wound of eyelid and periocular area	0.000	0.993	0.007
S01 Open wound of head	0.000	0.993	0.007
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.993	0.007
S01.3 Open wound of ear	0.000	0.993	0.007
S01.2 Open wound of nose	0.000	0.993	0.007
S92.0 Fracture of calcaneus	0.007	0.993	0.000
S06.2 Diffuse brain injury	0.000	0.993	0.007
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.993	0.007
C77.0 Lymph nodes of head, face and neck	0.007	0.993	0.000
I50 Heart failure	0.000	0.993	0.007
S06 Intracranial injury	0.000	0.993	0.007
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.993	0.007
M13.90 Arthritis, unspecified (Multiple sites)	0.007	0.993	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.994	0.006
S01.7 Multiple open wounds of head	0.000	0.994	0.006
S06.0 Concussion	0.000	0.994	0.006
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.994	0.006
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.994	0.006
L30.9 Dermatitis, unspecified	0.000	0.994	0.006
S06.4 Epidural haemorrhage	0.000	0.994	0.005
I47.1 Supraventricular tachycardia	0.000	0.994	0.006
S92 Fracture of foot, except ankle	0.005	0.994	0.000
R54 Senility	0.005	0.995	0.000
S06.3 Focal brain injury	0.000	0.995	0.005
S06.5 Traumatic subdural haemorrhage	0.000	0.995	0.005
S06.00 Concussion (without open intracranial wound)	0.000	0.995	0.005
S92.1 Fracture of talus	0.005	0.995	0.000
S92.01 Fracture of calcaneus (open)	0.005	0.995	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.995	0.005
S92.10 Fracture of talus (closed)	0.005	0.995	0.000
S06.9 Intracranial injury, unspecified	0.000	0.995	0.005
S01.4 Open wound of cheek and temporomandibular area	0.000	0.995	0.005
S06.7 Intracranial injury with prolonged coma	0.000	0.995	0.005
S06.1 Traumatic cerebral oedema	0.000	0.995	0.005
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.995	0.005
S06.8 Other intracranial injuries	0.000	0.995	0.005
S01.8 Open wound of other parts of head	0.000	0.995	0.005
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.995	0.004
S92.4 Fracture of great toe	0.004	0.995	0.000
S92.2 Fracture of other tarsal bone(s)	0.005	0.995	0.000
S00-S09 Injuries to the head	0.000	0.995	0.005
S06.01 Concussion (with open intracranial wound)	0.000	0.996	0.004
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.996	0.004
I34.1 Mitral (valve) prolapse	0.000	0.996	0.004
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.996	0.004
S01.0 Open wound of scalp	0.000	0.996	0.004
Q21.1 Atrial septal defect	0.004	0.996	0.000
I46.0 Cardiac arrest with successful resuscitation	0.000	0.996	0.004
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.996	0.004
S92.9 Fracture of foot, unspecified	0.004	0.996	0.000
S92.7 Multiple fractures of foot	0.004	0.996	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.996	0.004
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.996	0.004
I50.0 Congestive heart failure	0.000	0.996	0.004
S92.11 Fracture of talus (open)	0.004	0.996	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.996	0.004
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.996	0.004
S92.20 Fracture of other tarsal bone(s) (closed)	0.004	0.996	0.000
S92.41 Fracture of great toe (open)	0.004	0.996	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.996	0.004
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.996	0.004
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.996	0.004
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.996	0.004
S92.3 Fracture of metatarsal bone	0.004	0.996	0.000
S92.5 Fracture of other toe	0.004	0.996	0.000
S05 Injury of eye and orbit	0.000	0.996	0.004
S02 Fracture of skull and facial bones	0.000	0.996	0.004
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.996	0.003
S92.21 Fracture of other tarsal bone(s) (open)	0.003	0.996	0.000
S92.40 Fracture of great toe (closed)	0.003	0.996	0.000
S08 Traumatic amputation of part of head	0.000	0.996	0.003
S07 Crushing injury of head	0.000	0.996	0.003
S04 Injury of cranial nerves	0.000	0.996	0.003
S03 Dislocation, sprain and strain of joints and ligaments of head	0.000	0.996	0.003
K08.8 Other specified disorders of teeth and supporting structures	0.004	0.996	0.000
G47.3 Sleep apnoea	0.000	0.997	0.003
S02.4 Fracture of malar and maxillary bones	0.000	0.997	0.003
S02.2 Fracture of nasal bones	0.000	0.997	0.003
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.000	0.997	0.003
S92.71 Multiple fractures of foot (open)	0.003	0.997	0.000
S92.70 Multiple fractures of foot (closed)	0.003	0.997	0.000
S92.91 Fracture of foot, unspecified (open)	0.003	0.997	0.000
S92.90 Fracture of foot, unspecified (closed)	0.003	0.997	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.997	0.003
D47.3 Essential (haemorrhagic) thrombocythaemia	0.003	0.997	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.997	0.003
S05.8 Other injuries of eye and orbit	0.000	0.997	0.003
F52.2 Failure of genital response	0.000	0.997	0.003
C67.2 Lateral wall of bladder	0.000	0.997	0.003
S02.20 Fracture of nasal bones (closed)	0.000	0.997	0.003
K11.5 Sialolithiasis	0.003	0.997	0.000
S92.31 Fracture of metatarsal bone (open)	0.003	0.997	0.000
S92.51 Fracture of other toe (open)	0.003	0.997	0.000
S01.9 Open wound of head, part unspecified	0.000	0.997	0.003
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.997	0.003
S05.7 Avulsion of eye	0.000	0.997	0.003
S05.6 Penetrating wound of eyeball without foreign body	0.000	0.997	0.003
S05.5 Penetrating wound of eyeball with foreign body	0.000	0.997	0.003
S05.4 Penetrating wound of orbit with or without foreign body	0.000	0.997	0.003
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.997	0.003
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.000	0.997	0.003
S02.1 Fracture of base of skull	0.000	0.997	0.003
S02.8 Fractures of other skull and facial bones	0.000	0.997	0.003
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.000	0.997	0.003
S03.4 Sprain and strain of jaw	0.000	0.997	0.003
S03.3 Dislocation of other and unspecified parts of head	0.000	0.997	0.003
S03.2 Dislocation of tooth	0.000	0.997	0.003
S03.1 Dislocation of septal cartilage of nose	0.000	0.997	0.003
S03.0 Dislocation of jaw	0.000	0.997	0.003
S04.9 Injury of unspecified cranial nerve	0.000	0.997	0.003
S04.8 Injury of other cranial nerves	0.000	0.997	0.003
S04.7 Injury of accessory nerve	0.000	0.997	0.003
S04.6 Injury of acoustic nerve	0.000	0.997	0.003
S04.5 Injury of facial nerve	0.000	0.997	0.003
S04.4 Injury of abducent nerve	0.000	0.997	0.003
S04.3 Injury of trigeminal nerve	0.000	0.997	0.003
S04.2 Injury of trochlear nerve	0.000	0.997	0.003
S04.1 Injury of oculomotor nerve	0.000	0.997	0.003
S04.0 Injury of optic nerve and pathways	0.000	0.997	0.003
S07.9 Crushing injury of head, part unspecified	0.000	0.997	0.003
S07.8 Crushing injury of other parts of head	0.000	0.997	0.003
S07.1 Crushing injury of skull	0.000	0.997	0.003
S07.0 Crushing injury of face	0.000	0.997	0.003
S08.9 Traumatic amputation of unspecified part of head	0.000	0.997	0.003
S08.8 Traumatic amputation of other parts of head	0.000	0.997	0.003
S08.1 Traumatic amputation of ear	0.000	0.997	0.003
S08.0 Avulsion of scalp	0.000	0.997	0.003
S02.0 Fracture of vault of skull	0.000	0.997	0.003
B37.8 Candidiasis of other sites	0.000	0.997	0.003
I34.0 Mitral (valve) insufficiency	0.000	0.997	0.003
S02.5 Fracture of tooth	0.000	0.997	0.003
S05.1 Contusion of eyeball and orbital tissues	0.000	0.997	0.003
S02.3 Fracture of orbital floor	0.000	0.997	0.003
S61.0 Open wound of finger(s) without damage to nail	0.000	0.997	0.003
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.997	0.003
S02.7 Multiple fractures involving skull and facial bones	0.000	0.997	0.003
Q63 Other congenital malformations of kidney	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.003	0.997	0.000
R00.8 Other and unspecified abnormalities of heart beat	0.000	0.997	0.003
S02.21 Fracture of nasal bones (open)	0.000	0.997	0.003
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
S92.50 Fracture of other toe (closed)	0.002	0.997	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.003	0.997	0.000
S05.9 Injury of eye and orbit, part unspecified	0.000	0.997	0.002
Q63.0 Accessory kidney	0.003	0.997	0.000
J90 Pleural effusion, not elsewhere classified	0.000	0.997	0.003
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
I50.9 Heart failure, unspecified	0.000	0.997	0.003
Q63.2 Ectopic kidney	0.002	0.997	0.000
S91 Open wound of ankle and foot	0.002	0.997	0.000
S02.6 Fracture of mandible	0.000	0.998	0.002
Z92.6 Personal history of chemotherapy for neoplastic disease	0.000	0.998	0.002
L30 Other dermatitis	0.000	0.998	0.002
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.998	0.002
C67 Malignant neoplasm of bladder	0.000	0.998	0.002
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.998	0.002
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.000	0.998	0.002
S02.11 Fracture of base of skull (open)	0.000	0.998	0.002
F31.9 Bipolar affective disorder, unspecified	0.002	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
S02.81 Fractures of other skull and facial bones (open)	0.000	0.998	0.002
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.000	0.998	0.002
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.998	0.002
S02.51 Fracture of tooth (open)	0.000	0.998	0.002
S02.31 Fracture of orbital floor (open)	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
R00 Abnormalities of heart beat	0.000	0.998	0.002
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.998	0.002
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
G47.9 Sleep disorder, unspecified	0.000	0.998	0.002
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
G47 Sleep disorders	0.000	0.998	0.002
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
C67.1 Dome of bladder	0.000	0.998	0.002
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.998	0.002
S02.00 Fracture of vault of skull (closed)	0.000	0.998	0.002
C67.4 Posterior wall of bladder	0.000	0.998	0.002
S99.9 Unspecified injury of ankle and foot	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
C67.6 Ureteric orifice	0.000	0.998	0.002
S80.0 Contusion of knee	0.002	0.998	0.000
S91.0 Open wound of ankle	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.000	0.998	0.002
N39.4 Other specified urinary incontinence	0.000	0.998	0.002
S02.30 Fracture of orbital floor (closed)	0.000	0.998	0.002
S02.61 Fracture of mandible (open)	0.000	0.998	0.002
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
C67.8 Overlapping lesion of bladder	0.000	0.998	0.002
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
L30.5 Pityriasis alba	0.000	0.998	0.002
L30.4 Erythema intertrigo	0.000	0.998	0.002
L30.3 Infective dermatitis	0.000	0.998	0.002
L30.2 Cutaneous autosensitisation	0.000	0.998	0.002
L30.1 Dyshidrosis [pompholyx]	0.000	0.998	0.002
L30.0 Nummular dermatitis	0.000	0.998	0.002
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
C67.5 Bladder neck	0.000	0.998	0.002
C67.3 Anterior wall of bladder	0.000	0.998	0.002
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.998	0.000
I51 Complications and ill-defined descriptions of heart disease	0.000	0.998	0.002
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.998	0.002
C67.7 Urachus	0.000	0.998	0.002
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.998	0.002
C67.0 Trigone of bladder	0.000	0.998	0.002
N90.5 Atrophy of vulva	0.000	0.998	0.002
S80 Superficial injury of lower leg	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
Q60.6 Potter's syndrome	0.002	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.002	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.998	0.000
Q64.4 Malformation of urachus	0.002	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.998	0.000
Q64.0 Epispadias	0.002	0.998	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.002	0.998	0.000
S80.8 Other superficial injuries of lower leg	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.002	0.998	0.000
S80.9 Superficial injury of lower leg, unspecified	0.002	0.998	0.000
Q61 Cystic kidney disease	0.002	0.998	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.002	0.998	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.002	0.998	0.000
G47.4 Narcolepsy and cataplexy	0.000	0.998	0.002
G47.2 Disorders of the sleep-wake schedule	0.000	0.998	0.002
F31 Bipolar affective disorder	0.002	0.998	0.000
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
D43.2 Brain, unspecified	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.002	0.998	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.998	0.002
Q21.0 Ventricular septal defect	0.001	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.1 Traumatic amputation of one toe	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
G47.8 Other sleep disorders	0.000	0.998	0.002
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.002	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.002	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.002	0.998	0.000
S09 Other and unspecified injuries of head	0.000	0.998	0.001
I51.5 Myocardial degeneration	0.000	0.998	0.002
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.998	0.002
J69.0 Pneumonitis due to food and vomit	0.002	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.002	0.998	0.000
Q62.8 Other congenital malformations of ureter	0.001	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.001	0.998	0.000
Q62.6 Malposition of ureter	0.001	0.998	0.000
Q62.5 Duplication of ureter	0.001	0.998	0.000
Q62.4 Agenesis of ureter	0.001	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.001	0.998	0.000
Q62.2 Congenital megaloureter	0.001	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.001	0.998	0.000
Q62.0 Congenital hydronephrosis	0.001	0.998	0.000
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
S80.7 Multiple superficial injuries of lower leg	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.001	0.998	0.000
Q61.4 Renal dysplasia	0.001	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.001	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.001	0.998	0.000
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.998	0.001
L30.8 Other specified dermatitis	0.000	0.998	0.001
Q28 Other congenital malformations of circulatory system	0.001	0.998	0.000
Q26 Congenital malformations of great veins	0.001	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.001	0.998	0.000
M13.98 Arthritis, unspecified (Other)	0.002	0.998	0.000
H65.2 Chronic serous otitis media	0.002	0.998	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.001	0.998	0.000
Q25.8 Other congenital malformations of great arteries	0.001	0.998	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.001	0.998	0.000
Q25.6 Stenosis of pulmonary artery	0.001	0.998	0.000
Q25.5 Atresia of pulmonary artery	0.001	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.001	0.998	0.000
Q25.3 Stenosis of aorta	0.001	0.998	0.000
Q25.2 Atresia of aorta	0.001	0.998	0.000
Q25.0 Patent ductus arteriosus	0.001	0.998	0.000
F31.8 Other bipolar affective disorders	0.001	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.998	0.002
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.001
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.001
F52.7 Excessive sexual drive	0.000	0.998	0.001
F52.6 Nonorganic dyspareunia	0.000	0.998	0.001
F52.5 Nonorganic vaginismus	0.000	0.998	0.001
F52.4 Premature ejaculation	0.000	0.998	0.001
F52.3 Orgasmic dysfunction	0.000	0.998	0.001
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.998	0.001
F52.0 Lack or loss of sexual desire	0.000	0.998	0.001
I51.4 Myocarditis, unspecified	0.000	0.998	0.001
S90.7 Multiple superficial injuries of ankle and foot	0.001	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.001	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.001	0.998	0.000
S90.0 Contusion of ankle	0.001	0.998	0.000
S02.60 Fracture of mandible (closed)	0.000	0.998	0.001
C67.9 Bladder, unspecified	0.000	0.998	0.002
S93.4 Sprain and strain of ankle	0.001	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.998	0.000
Q24 Other congenital malformations of heart	0.001	0.998	0.000
E11.3 With ophthalmic complications	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.001	0.998	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.998	0.002
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.001	0.998	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.998	0.001
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.001	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.001	0.998	0.000
S09.7 Multiple injuries of head	0.000	0.998	0.001
S09.2 Traumatic rupture of ear drum	0.000	0.998	0.001
S09.1 Injury of muscle and tendon of head	0.000	0.998	0.001
S09.0 Injury of blood vessels of head, not elsewhere classified	0.000	0.998	0.001
C44.2 Skin of ear and external auricular canal	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations