TreeWAS – Variant ID: rs16885294

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M17.9 Gonarthrosis, unspecified	0.000	0.958	0.042
M17 Gonarthrosis [arthrosis of knee]	0.000	0.962	0.038
M17.1 Other primary gonarthrosis	0.000	0.964	0.036
M17.0 Primary gonarthrosis, bilateral	0.000	0.968	0.032
M17.3 Other posttraumatic gonarthrosis	0.000	0.972	0.028
M17.4 Other secondary gonarthrosis, bilateral	0.000	0.973	0.027
M17.2 Posttraumatic gonarthrosis, bilateral	0.000	0.973	0.027
M17.5 Other secondary gonarthrosis	0.000	0.974	0.026
M54.56 Low back pain (Lumbar region)	0.009	0.991	0.000
D70 Agranulocytosis	0.000	0.991	0.009
N18.3 Chronic kidney disease, stage 3	0.000	0.992	0.008
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.006	0.994	0.000
Y42.5 Other oestrogens and progestogens	0.006	0.994	0.000
M15-M19 Arthrosis	0.000	0.994	0.006
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.005	0.995	0.000
M06.9 Rheumatoid arthritis, unspecified	0.005	0.995	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.005	0.995	0.000
H25.9 Senile cataract, unspecified	0.000	0.995	0.005
M18 Arthrosis of first carpometacarpal joint	0.000	0.996	0.004
N18 Chronic renal failure	0.000	0.996	0.004
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.004	0.996	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.004	0.996	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.004	0.996	0.000
F10.3 Withdrawal state	0.004	0.996	0.000
M15 Polyarthrosis	0.000	0.996	0.004
N18.9 Chronic renal failure, unspecified	0.000	0.996	0.004
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.004	0.996	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.004	0.996	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.996	0.004
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.003	0.996	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.996	0.004
Y40 Systemic antibiotics	0.004	0.996	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.996	0.003
Y43 Primarily systemic agents	0.003	0.997	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.997	0.003
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.997	0.003
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.997	0.003
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.997	0.003
N17-N19 Renal failure	0.000	0.997	0.003
N18.8 Other chronic renal failure	0.000	0.997	0.003
N18.1 Chronic kidney disease, stage 1	0.000	0.997	0.003
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.003	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
Y43.3 Other antineoplastic drugs	0.003	0.997	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
N19 Unspecified renal failure	0.000	0.997	0.003
N17 Acute renal failure	0.000	0.997	0.003
N17.9 Acute renal failure, unspecified	0.000	0.997	0.003
M19 Other arthrosis	0.000	0.997	0.003
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.997	0.003
Y40.0 Penicillins	0.003	0.997	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.997	0.003
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
M06 Other rheumatoid arthritis	0.003	0.997	0.000
M15.9 Polyarthrosis, unspecified	0.000	0.997	0.003
M15.0 Primary generalised (osteo)arthrosis	0.000	0.997	0.003
M15.8 Other polyarthrosis	0.000	0.997	0.003
M15.4 Erosive (osteo)arthrosis	0.000	0.997	0.003
M15.3 Secondary multiple arthrosis	0.000	0.997	0.003
M15.2 Bouchard's nodes (with arthropathy)	0.000	0.997	0.003
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.003	0.997	0.000
M19.0 Primary arthrosis of other joints	0.000	0.997	0.003
N18.2 Chronic kidney disease, stage 2	0.000	0.997	0.003
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y48 Anaesthetics and therapeutic gases	0.003	0.997	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.997	0.003
N18.0 End-stage renal disease	0.000	0.997	0.003
Y40.1 Cefalosporins and other -lactam antibiotics	0.003	0.997	0.000
Y44 Agents primarily affecting blood constituents	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
Y59 Other and unspecified vaccines and biological substances	0.003	0.997	0.000
Y58 Bacterial vaccines	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.003	0.997	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.997	0.000
D75.1 Secondary polycythaemia	0.000	0.997	0.003
N18.5 Chronic kidney disease, stage 5	0.000	0.997	0.003
Y53.4 Other laxatives	0.003	0.997	0.000
M15.1 Heberden's nodes (with arthropathy)	0.000	0.997	0.003
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.997	0.003
D74 Methaemoglobinaemia	0.000	0.997	0.003
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.997	0.003
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.997	0.003
Y40.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
Y40.6 Rifamycins	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.003	0.997	0.000
Y40.4 Tetracyclines	0.003	0.997	0.000
Y40.3 Macrolides	0.003	0.997	0.000
Y40.2 Chloramphenicol group	0.003	0.997	0.000
Y42.7 Androgens and anabolic congeners	0.003	0.997	0.000
Y49.2 Other and unspecified antidepressants	0.003	0.997	0.000
M10.99 Gout, unspecified (Site unspecified)	0.003	0.997	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
Y43.9 Primarily systemic agent, unspecified	0.003	0.997	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.003	0.997	0.000
Y43.6 Enzymes, not elsewhere classified	0.003	0.997	0.000
Y43.5 Acidifying and alkalising agents	0.003	0.997	0.000
Y43.2 Antineoplastic natural products	0.003	0.997	0.000
Y43.1 Antineoplastic antimetabolites	0.003	0.997	0.000
Y43.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
Y54.5 Other diuretics	0.003	0.997	0.000
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
Y43.4 Immunosuppressive agents	0.003	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.997	0.003
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.997	0.003
F10.2 Dependence syndrome	0.003	0.997	0.000
N17.8 Other acute renal failure	0.000	0.997	0.002
N17.2 Acute renal failure with medullary necrosis	0.000	0.997	0.002
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.997	0.002
N17.0 Acute renal failure with tubular necrosis	0.000	0.997	0.002
M19.8 Other specified arthrosis	0.000	0.997	0.002
M19.2 Other secondary arthrosis	0.000	0.997	0.002
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.997	0.000
M06.4 Inflammatory polyarthropathy	0.002	0.997	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.997	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
Y53.7 Emetics	0.002	0.997	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.997	0.000
Y53.5 Digestants	0.002	0.997	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.997	0.000
Y53.2 Stimulant laxatives	0.002	0.997	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.997	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.997	0.000
D75.2 Essential thrombocytosis	0.000	0.997	0.002
D75.0 Familial erythrocytosis	0.000	0.997	0.002
Y48.3 Local anaesthetics	0.002	0.997	0.000
M06.3 Rheumatoid nodule	0.002	0.997	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.997	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.997	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.997	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.997	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.997	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.997	0.000
M06.8 Other specified rheumatoid arthritis	0.002	0.997	0.000
M06.2 Rheumatoid bursitis	0.002	0.997	0.000
M06.1 Adult-onset Still's disease	0.002	0.997	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.000	0.997	0.002
M15.99 Polyosteoarthritis, unspecified	0.000	0.997	0.002
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.997	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.997	0.002
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.997	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.997	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.997	0.000
Y54.7 Agents affecting calcification	0.002	0.997	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.997	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.997	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.997	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.997	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.997	0.000
Y54.0 Mineralocorticoids	0.002	0.997	0.000
M19.08 Primary arthrosis of other joints (Other)	0.000	0.997	0.002
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.997	0.002
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.997	0.002
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.997	0.002
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.997	0.002
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.997	0.002
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.997	0.000
Y52.7 Peripheral vasodilators	0.002	0.997	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.997	0.000
Y52.1 Calcium-channel blockers	0.002	0.997	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.997	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.997	0.003
F10 Mental and behavioural disorders due to use of alcohol	0.003	0.997	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M19.1 Posttraumatic arthrosis of other joints	0.000	0.998	0.002
Y44.2 Anticoagulants	0.002	0.998	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.998	0.002
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.998	0.002
M10.9 Gout, unspecified	0.002	0.998	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.998	0.002
H36.0 Diabetic retinopathy	0.000	0.998	0.002
D74.9 Methaemoglobinaemia, unspecified	0.000	0.998	0.002
D74.8 Other methaemoglobinaemias	0.000	0.998	0.002
D74.0 Congenital methaemoglobinaemia	0.000	0.998	0.002
D76.3 Other histiocytosis syndromes	0.000	0.998	0.002
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.998	0.002
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.998	0.002
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.998	0.002
D72 Other disorders of white blood cells	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
F10.5 Psychotic disorder	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.998	0.002
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.002	0.998	0.000
M06.0 Seronegative rheumatoid arthritis	0.002	0.998	0.000
D73 Diseases of spleen	0.000	0.998	0.002
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.002	0.998	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.002	0.998	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.002	0.998	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.002	0.998	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.002	0.998	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.002	0.998	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.002	0.998	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.002	0.998	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.000	0.998	0.002
M19.28 Other secondary arthrosis (Other)	0.000	0.998	0.002
M19.27 Other secondary arthrosis (Ankle and foot)	0.000	0.998	0.002
M19.26 Other secondary arthrosis of other joints-Lower leg	0.000	0.998	0.002
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.000	0.998	0.002
M19.24 Other secondary arthrosis (Hand)	0.000	0.998	0.002
M19.23 Other secondary arthrosis (Forearm)	0.000	0.998	0.002
M19.22 Other secondary arthrosis (Upper arm)	0.000	0.998	0.002
M19.21 Other secondary arthrosis (Shoulder region)	0.000	0.998	0.002
M19.20 Other secondary arthrosis (Multiple sites)	0.000	0.998	0.002
M19.89 Other specified arthrosis (Site unspecified)	0.000	0.998	0.002
M19.88 Other specified arthrosis (Other)	0.000	0.998	0.002
M19.87 Other specified arthrosis (Ankle and foot)	0.000	0.998	0.002
M19.86 Other specified arthrosis (Lower leg)	0.000	0.998	0.002
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.000	0.998	0.002
M19.84 Other specified arthrosis (Hand)	0.000	0.998	0.002
M19.83 Other specified arthrosis (Forearm)	0.000	0.998	0.002
M19.82 Other specified arthrosis (Upper arm)	0.000	0.998	0.002
M19.81 Other specified arthrosis (Shoulder region)	0.000	0.998	0.002
M19.80 Other specified arthrosis (Multiple sites)	0.000	0.998	0.002
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
M06.34 Rheumatoid nodule (Hand)	0.002	0.998	0.000
I84.1 Internal haemorrhoids with other complications	0.000	0.998	0.002
M79.6 Pain in limb	0.002	0.998	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.002	0.998	0.000
M06.38 Rheumatoid nodule (Other)	0.002	0.998	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.002	0.998	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.002	0.998	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.002	0.998	0.000
M06.33 Rheumatoid nodule (Forearm)	0.002	0.998	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.002	0.998	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.002	0.998	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.002	0.998	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.002	0.998	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.002	0.998	0.000
M06.18 Adult-onset Still's disease (Other)	0.002	0.998	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.002	0.998	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.002	0.998	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.002	0.998	0.000
M06.14 Adult-onset Still's disease (Hand)	0.002	0.998	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.002	0.998	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.002	0.998	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.002	0.998	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.002	0.998	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.002	0.998	0.000
M06.28 Rheumatoid bursitis (Other)	0.002	0.998	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.002	0.998	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.002	0.998	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.002	0.998	0.000
M06.24 Rheumatoid bursitis (Hand)	0.002	0.998	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.002	0.998	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.002	0.998	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.002	0.998	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.002	0.998	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.002	0.998	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.002	0.998	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
M79.66 Pain in limb (Lower leg)	0.002	0.998	0.000
M54.5 Low back pain	0.002	0.998	0.000
M79.68 Pain in limb (Other)	0.002	0.998	0.000
F10.9 Unspecified mental and behavioural disorder	0.002	0.998	0.000
F10.8 Other mental and behavioural disorders	0.002	0.998	0.000
F10.7 Residual and late-onset psychotic disorder	0.002	0.998	0.000
F10.6 Amnesic syndrome	0.002	0.998	0.000
M10 Gout	0.002	0.998	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.000	0.998	0.002
M19.18 Post-traumatic arthrosis of other joints (Other)	0.000	0.998	0.002
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.000	0.998	0.002
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.000	0.998	0.002
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.000	0.998	0.002
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.000	0.998	0.002
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.000	0.998	0.002
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.000	0.998	0.002
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.000	0.998	0.002
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
Y45.1 Salicylates	0.002	0.998	0.000
M10.98 Gout, unspecified (Other)	0.002	0.998	0.000
M10.96 Gout, unspecified (Lower leg)	0.002	0.998	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M10.94 Gout, unspecified (Hand)	0.002	0.998	0.000
M10.93 Gout, unspecified (Forearm)	0.002	0.998	0.000
M10.92 Gout, unspecified (Upper arm)	0.002	0.998	0.000
M10.91 Gout, unspecified (Shoulder region)	0.002	0.998	0.000
M10.90 Gout, unspecified (Multiple sites)	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.002
M79.09 Rheumatism, unspecified (Site unspecified)	0.002	0.998	0.000
M79.69 Pain in limb (Site unspecified)	0.002	0.998	0.000
D72.9 Disorder of white blood cells, unspecified	0.000	0.998	0.002
D72.0 Genetic anomalies of leukocytes	0.000	0.998	0.002
M10.97 Gout, unspecified (Ankle and foot)	0.002	0.998	0.000
C18.9 Colon, unspecified	0.000	0.998	0.002
F10.4 Withdrawal state with delirium	0.002	0.998	0.000
M79.63 Pain in limb (Forearm)	0.002	0.998	0.000
C18.7 Sigmoid colon	0.000	0.998	0.002
M06.08 Seronegative rheumatoid arthritis (Other)	0.002	0.998	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.002	0.998	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
D72.1 Eosinophilia	0.000	0.998	0.001
D73.9 Disease of spleen, unspecified	0.000	0.998	0.001
D73.8 Other diseases of spleen	0.000	0.998	0.001
D73.4 Cyst of spleen	0.000	0.998	0.001
D73.3 Abscess of spleen	0.000	0.998	0.001
D73.2 Chronic congestive splenomegaly	0.000	0.998	0.001
D73.1 Hypersplenism	0.000	0.998	0.001
F10.0 Acute intoxication	0.002	0.998	0.000
M79.61 Pain in limb (Shoulder region)	0.002	0.998	0.000
M79.0 Rheumatism, unspecified	0.002	0.998	0.000
M05-M14 Inflammatory polyarthropathies	0.002	0.998	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.002	0.998	0.000
J33.9 Nasal polyp, unspecified	0.000	0.998	0.002
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
M54.55 Low back pain (Thoracolumbar region)	0.002	0.998	0.000
M54.54 Low back pain-Thoracic	0.002	0.998	0.000
M54.53 Low back pain-Cervicothoracic	0.002	0.998	0.000
M54.52 Low back pain-Cervical	0.002	0.998	0.000
M54.51 Low back pain-Occipit-atl-axl	0.002	0.998	0.000
M54.50 Low back pain (Multiple sites in spine)	0.002	0.998	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.002	0.998	0.000
Z04.8 Examination and observation for other specified reasons	0.000	0.998	0.002
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M79.64 Pain in limb (Hand)	0.002	0.998	0.000
M79.62 Pain in limb (Upper arm)	0.002	0.998	0.000
E11.3 With ophthalmic complications	0.000	0.998	0.002
M10.4 Other secondary gout	0.002	0.998	0.000
M10.3 Gout due to impairment of renal function	0.002	0.998	0.000
M10.2 Drug-induced gout	0.002	0.998	0.000
M10.1 Lead-induced gout	0.002	0.998	0.000
M10.0 Idiopathic gout	0.002	0.998	0.000
D73.5 Infarction of spleen	0.000	0.998	0.001
M79.2 Neuralgia and neuritis, unspecified	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.001	0.998	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.002	0.998	0.000
E10.3 With ophthalmic complications	0.000	0.998	0.002
E27 Other disorders of adrenal gland	0.002	0.998	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.002	0.998	0.000
M79.8 Other specified soft tissue disorders	0.002	0.998	0.000
M07 Psoriatic and enteropathic arthropathies	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.001	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.001	0.998	0.000
M05 Seropositive rheumatoid arthritis	0.002	0.998	0.000
M79.08 Rheumatism, unspecified (Other)	0.001	0.998	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.001	0.998	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.001	0.998	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M79.04 Rheumatism, unspecified (Hand)	0.001	0.998	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.001	0.998	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.001	0.998	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.001	0.998	0.000
M79.5 Residual foreign body in soft tissue	0.001	0.998	0.000
M79.70 Fibromyalgia (Multiple sites)	0.001	0.998	0.000
H25.1 Senile nuclear cataract	0.000	0.998	0.002
M79.7 Fibromyalgia	0.001	0.998	0.000
M79.1 Myalgia	0.001	0.998	0.000
M14 Arthropathies in other diseases classified elsewhere	0.001	0.998	0.000
M12 Other specific arthropathies	0.001	0.998	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.001	0.998	0.000
M08 Juvenile arthritis	0.001	0.998	0.000
M79.60 Pain in limb (Multiple sites)	0.001	0.998	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.001	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.998	0.002
M79.9 Soft tissue disorder, unspecified	0.001	0.998	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.001	0.998	0.000
M79.3 Panniculitis, unspecified	0.001	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.001	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.001	0.998	0.001
D86.9 Sarcoidosis, unspecified	0.000	0.998	0.001
M10.09 Idiopathic gout (Site unspecified)	0.001	0.998	0.000
M10.08 Idiopathic gout (Other)	0.001	0.998	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.001	0.998	0.000
M10.06 Idiopathic gout (Lower leg)	0.001	0.998	0.000
M10.05 Idiopathic gout (Pelvic region and thigh)	0.001	0.998	0.000
M10.04 Idiopathic gout (Hand)	0.001	0.998	0.000
M10.03 Idiopathic gout (Forearm)	0.001	0.998	0.000
M10.02 Idiopathic gout (Upper arm)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations