TreeWAS – Variant ID: rs169219

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
K90 Intestinal malabsorption	0.567	0.433	0.000
K90.9 Intestinal malabsorption, unspecified	0.465	0.535	0.000
D64.9 Anaemia, unspecified	0.429	0.571	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.416	0.584	0.000
K90.8 Other intestinal malabsorption	0.408	0.592	0.000
K90.3 Pancreatic steatorrhoea	0.406	0.593	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.406	0.593	0.000
K90.1 Tropical sprue	0.406	0.593	0.000
D64 Other anaemias	0.320	0.680	0.000
D64.0 Hereditary sideroblastic anaemia	0.241	0.759	0.000
D64.3 Other sideroblastic anaemias	0.241	0.759	0.000
D60-D64 Aplastic and other anaemias	0.238	0.762	0.000
D64.4 Congenital dyserythropoietic anaemia	0.230	0.770	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.230	0.770	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.230	0.770	0.000
D62 Acute posthaemorrhagic anaemia	0.227	0.773	0.000
D64.8 Other specified anaemias	0.209	0.790	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.179	0.821	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.146	0.854	0.000
D50.9 Iron deficiency anaemia, unspecified	0.140	0.860	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.136	0.864	0.000
D60.8 Other acquired pure red cell aplasias	0.128	0.872	0.000
D60.1 Transient acquired pure red cell aplasia	0.128	0.872	0.000
D60.0 Chronic acquired pure red cell aplasia	0.128	0.872	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.119	0.881	0.000
D50 Iron deficiency anaemia	0.111	0.889	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.110	0.890	0.000
D50-D53 Nutritional anaemias	0.109	0.891	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.105	0.895	0.000
D61 Other aplastic anaemias	0.094	0.906	0.000
D52 Folate deficiency anaemia	0.085	0.915	0.000
D50.1 Sideropenic dysphagia	0.081	0.919	0.000
D53 Other nutritional anaemias	0.078	0.921	0.000
D80-D89 Certain disorders involving the immune mechanism	0.073	0.927	0.000
D55-D59 Haemolytic anaemias	0.073	0.927	0.000
D61.0 Constitutional aplastic anaemia	0.072	0.928	0.000
D51 Vitamin B12 deficiency anaemia	0.069	0.931	0.000
D61.8 Other specified aplastic anaemias	0.067	0.932	0.000
D61.3 Idiopathic aplastic anaemia	0.067	0.932	0.000
D61.2 Aplastic anaemia due to other external agents	0.067	0.932	0.000
D52.9 Folate deficiency anaemia, unspecified	0.067	0.933	0.000
H93.1 Tinnitus	0.000	0.935	0.065
D52.8 Other folate deficiency anaemias	0.061	0.939	0.000
D52.1 Drug-induced folate deficiency anaemia	0.061	0.939	0.000
D52.0 Dietary folate deficiency anaemia	0.061	0.939	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.059	0.941	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.059	0.941	0.000
D53.8 Other specified nutritional anaemias	0.056	0.943	0.000
D53.2 Scorbutic anaemia	0.056	0.943	0.000
D53.0 Protein deficiency anaemia	0.056	0.943	0.000
D83 Common variable immunodeficiency	0.056	0.943	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.055	0.945	0.000
D61.1 Drug-induced aplastic anaemia	0.054	0.945	0.001
D84 Other immunodeficiencies	0.054	0.946	0.000
D53.9 Nutritional anaemia, unspecified	0.053	0.947	0.000
D57 Sickle-cell disorders	0.053	0.947	0.000
D55 Anaemia due to enzyme disorders	0.053	0.947	0.000
D81 Combined immunodeficiencies	0.053	0.947	0.000
D80 Immunodeficiency with predominantly antibody defects	0.052	0.948	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.052	0.948	0.000
D58 Other hereditary haemolytic anaemias	0.052	0.948	0.000
D59 Acquired haemolytic anaemia	0.051	0.949	0.000
D56 Thalassaemia	0.050	0.950	0.000
D82 Immunodeficiency associated with other major defects	0.050	0.950	0.000
D51.2 Transcobalamin II deficiency	0.050	0.950	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.050	0.950	0.000
D86 Sarcoidosis	0.046	0.954	0.000
D84.9 Immunodeficiency, unspecified	0.045	0.955	0.000
D63.0 Anaemia in neoplastic disease	0.045	0.955	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.045	0.955	0.000
K90-K93 Other diseases of the digestive system	0.045	0.955	0.000
D83.9 Common variable immunodeficiency, unspecified	0.044	0.955	0.000
E10.1 With ketoacidosis	0.044	0.956	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.044	0.956	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.042	0.958	0.000
D83.8 Other common variable immunodeficiencies	0.041	0.959	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.041	0.959	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.041	0.959	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.041	0.959	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.041	0.959	0.000
D86.8 Sarcoidosis of other and combined sites	0.041	0.959	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.040	0.960	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.039	0.961	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.039	0.961	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.038	0.962	0.000
D55.8 Other anaemias due to enzyme disorders	0.038	0.962	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.038	0.962	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.038	0.962	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.038	0.962	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.038	0.962	0.000
D57.8 Other sickle-cell disorders	0.038	0.962	0.000
D57.3 Sickle-cell trait	0.038	0.962	0.000
D57.2 Double heterozygous sickling disorders	0.038	0.962	0.000
D57.1 Sickle-cell anaemia without crisis	0.038	0.962	0.000
D57.0 Sickle-cell anaemia with crisis	0.038	0.962	0.000
D81.9 Combined immunodeficiency, unspecified	0.038	0.962	0.000
D81.8 Other combined immunodeficiencies	0.038	0.962	0.000
D81.7 Major histocompatibility complex class II deficiency	0.038	0.962	0.000
D81.6 Major histocompatibility complex class I deficiency	0.038	0.962	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.038	0.962	0.000
D81.4 Nezelof's syndrome	0.038	0.962	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.038	0.962	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.038	0.962	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.038	0.962	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.038	0.962	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.038	0.962	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.037	0.962	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.037	0.962	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.037	0.962	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.037	0.962	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.037	0.962	0.000
D89.3 Immune reconstitution syndrome	0.037	0.963	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.037	0.963	0.000
D58.1 Hereditary elliptocytosis	0.037	0.963	0.000
D58.0 Hereditary spherocytosis	0.037	0.963	0.000
E83 Disorders of mineral metabolism	0.000	0.963	0.037
H93 Other disorders of ear, not elsewhere classified	0.000	0.963	0.037
D59.8 Other acquired haemolytic anaemias	0.037	0.963	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.037	0.963	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.037	0.963	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.037	0.963	0.000
D59.3 Haemolytic-uraemic syndrome	0.037	0.963	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.037	0.963	0.000
D56.9 Thalassaemia, unspecified	0.036	0.964	0.000
D56.8 Other thalassaemias	0.036	0.964	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.036	0.964	0.000
D56.2 Delta-beta thalassaemia	0.036	0.964	0.000
D56.0 Alpha thalassaemia	0.036	0.964	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.036	0.964	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.036	0.964	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.036	0.964	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.036	0.964	0.000
D82.2 Immunodeficiency with short-limbed stature	0.036	0.964	0.000
D82.0 Wiskott-Aldrich syndrome	0.036	0.964	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.036	0.964	0.000
D56.1 Beta thalassaemia	0.036	0.964	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.036	0.964	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.035	0.964	0.000
D89.1 Cryoglobulinaemia	0.035	0.965	0.000
D86.1 Sarcoidosis of lymph nodes	0.035	0.965	0.000
D84.8 Other specified immunodeficiencies	0.035	0.965	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.035	0.965	0.000
D84.1 Defects in the complement system	0.034	0.966	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.034	0.966	0.000
D56.3 Thalassaemia trait	0.034	0.966	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.033	0.967	0.000
D82.1 Di George's syndrome	0.033	0.967	0.000
D58.2 Other haemoglobinopathies	0.032	0.967	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.032	0.968	0.000
D59.1 Other autoimmune haemolytic anaemias	0.032	0.968	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.032	0.968	0.000
D86.3 Sarcoidosis of skin	0.031	0.969	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.031	0.969	0.000
D69 Purpura and other haemorrhagic conditions	0.029	0.971	0.000
H93.9 Disorder of ear, unspecified	0.000	0.971	0.029
D69.3 Idiopathic thrombocytopenic purpura	0.028	0.972	0.000
D50.8 Other iron deficiency anaemias	0.028	0.972	0.000
H93.3 Disorders of acoustic nerve	0.000	0.972	0.028
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.973	0.027
E83.8 Other disorders of mineral metabolism	0.000	0.973	0.027
E83.2 Disorders of zinc metabolism	0.000	0.973	0.027
E83.0 Disorders of copper metabolism	0.000	0.973	0.027
H93.2 Other abnormal auditory perceptions	0.000	0.973	0.027
H93.0 Degenerative and vascular disorders of ear	0.000	0.973	0.027
H93.8 Other specified disorders of ear	0.000	0.974	0.026
C50.9 Breast, unspecified	0.000	0.976	0.024
D69.2 Other nonthrombocytopenic purpura	0.024	0.976	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.023	0.976	0.000
K93.1 Megacolon in Chagas' disease	0.023	0.976	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.023	0.976	0.000
D86.0 Sarcoidosis of lung	0.023	0.977	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.023	0.977	0.000
D69.4 Other primary thrombocytopenia	0.023	0.977	0.000
D69.0 Allergic purpura	0.022	0.978	0.000
D67 Hereditary factor IX deficiency	0.022	0.978	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.022	0.978	0.000
D69.8 Other specified haemorrhagic conditions	0.022	0.978	0.000
D66 Hereditary factor VIII deficiency	0.021	0.979	0.000
D69.1 Qualitative platelet defects	0.020	0.979	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.019	0.981	0.000
D69.9 Haemorrhagic condition, unspecified	0.018	0.982	0.000
C50 Malignant neoplasm of breast	0.000	0.984	0.016
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.016	0.984	0.000
C50.2 Upper-inner quadrant of breast	0.000	0.984	0.016
D86.9 Sarcoidosis, unspecified	0.015	0.985	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.985	0.015
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.014	0.986	0.000
D74 Methaemoglobinaemia	0.014	0.986	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.014	0.986	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.014	0.986	0.000
C50.8 Overlapping lesion of breast	0.000	0.986	0.014
D69.5 Secondary thrombocytopenia	0.013	0.986	0.000
D76.3 Other histiocytosis syndromes	0.013	0.986	0.000
C50.5 Lower-outer quadrant of breast	0.000	0.987	0.013
D75.0 Familial erythrocytosis	0.013	0.987	0.000
D75 Other diseases of blood and blood-forming organs	0.013	0.987	0.000
C50.0 Nipple and areola	0.000	0.988	0.012
C77.9 Lymph node, unspecified	0.000	0.988	0.012
G62.9 Polyneuropathy, unspecified	0.012	0.988	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.011	0.988	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.011	0.988	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.011	0.988	0.000
C50.1 Central portion of breast	0.000	0.989	0.011
K91.9 Postprocedural disorder of digestive system, unspecified	0.011	0.989	0.000
G61.0 Guillain-Barre syndrome	0.011	0.989	0.000
C18.7 Sigmoid colon	0.011	0.989	0.000
C50.6 Axillary tail of breast	0.000	0.989	0.011
D61.9 Aplastic anaemia, unspecified	0.010	0.989	0.001
K91.4 Colostomy and enterostomy malfunction	0.011	0.989	0.000
K91.5 Postcholecystectomy syndrome	0.011	0.989	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.010	0.989	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.010	0.990	0.000
H90-H95 Other disorders of ear	0.000	0.990	0.010
D74.9 Methaemoglobinaemia, unspecified	0.010	0.990	0.000
D74.8 Other methaemoglobinaemias	0.010	0.990	0.000
D74.0 Congenital methaemoglobinaemia	0.010	0.990	0.000
G62 Other polyneuropathies	0.010	0.990	0.000
G70.0 Myasthenia gravis	0.000	0.990	0.010
G61 Inflammatory polyneuropathy	0.010	0.990	0.000
K91.1 Postgastric surgery syndromes	0.010	0.990	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.010	0.990	0.000
N49.2 Inflammatory disorders of scrotum	0.000	0.990	0.010
D75.2 Essential thrombocytosis	0.009	0.990	0.000
D72 Other disorders of white blood cells	0.009	0.991	0.000
G61.8 Other inflammatory polyneuropathies	0.009	0.991	0.000
G62.8 Other specified polyneuropathies	0.009	0.991	0.000
H92 Otalgia and effusion of ear	0.000	0.991	0.009
S92.30 Fracture of metatarsal bone (closed)	0.009	0.991	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.008	0.992	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.008	0.992	0.000
E10 Insulin-dependent diabetes mellitus	0.008	0.992	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.992	0.008
E03.9 Hypothyroidism, unspecified	0.008	0.992	0.000
H92.0 Otalgia	0.000	0.992	0.008
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.992	0.007
E10.2 With renal complications	0.008	0.992	0.000
G62.2 Polyneuropathy due to other toxic agents	0.007	0.993	0.000
G61.1 Serum neuropathy	0.007	0.993	0.000
R31 Unspecified haematuria	0.000	0.993	0.007
H92.1 Otorrhoea	0.000	0.993	0.007
G64 Other disorders of peripheral nervous system	0.007	0.993	0.000
G62.1 Alcoholic polyneuropathy	0.007	0.993	0.000
D72.9 Disorder of white blood cells, unspecified	0.007	0.993	0.000
D72.0 Genetic anomalies of leukocytes	0.007	0.993	0.000
C50.3 Lower-inner quadrant of breast	0.000	0.993	0.007
E10.7 With multiple complications	0.007	0.993	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.993	0.007
C50-C50 Malignant neoplasm of breast	0.000	0.993	0.007
G62.0 Drug-induced polyneuropathy	0.006	0.993	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.006	0.993	0.000
E10.0 With coma	0.006	0.993	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.006	0.994	0.000
G70 Myasthenia gravis and other myoneural disorders	0.000	0.994	0.006
K91.3 Postoperative intestinal obstruction	0.006	0.994	0.000
E10.8 With unspecified complications	0.006	0.994	0.000
F06.7 Mild cognitive disorder	0.000	0.994	0.006
H92.2 Otorrhagia	0.000	0.994	0.006
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.994	0.006
G60 Hereditary and idiopathic neuropathy	0.006	0.994	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.006	0.994	0.000
H90 Conductive and sensorineural hearing loss	0.000	0.994	0.006
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.994	0.005
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.994	0.005
S92.3 Fracture of metatarsal bone	0.006	0.994	0.000
E10.6 With other specified complications	0.005	0.994	0.000
E10.3 With ophthalmic complications	0.006	0.994	0.000
J04.0 Acute laryngitis	0.006	0.994	0.000
D72.1 Eosinophilia	0.005	0.995	0.000
E10.5 With peripheral circulatory complications	0.005	0.995	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.995	0.005
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.995	0.005
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.995	0.005
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.995	0.005
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.995	0.005
G70.9 Myoneural disorder, unspecified	0.000	0.995	0.005
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.995	0.005
G60.8 Other hereditary and idiopathic neuropathies	0.005	0.995	0.000
D72.8 Other specified disorders of white blood cells	0.005	0.995	0.000
D68 Other coagulation defects	0.005	0.995	0.000
G70.8 Other specified myoneural disorders	0.000	0.995	0.005
G70.2 Congenital and developmental myasthenia	0.000	0.995	0.005
G70.1 Toxic myoneural disorders	0.000	0.995	0.005
H90.0 Conductive hearing loss, bilateral	0.000	0.995	0.005
N49.8 Inflammatory disorders of other specified male genital organs	0.000	0.995	0.005
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.005	0.995	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.995	0.005
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.995	0.005
L27.1 Localised skin eruption due to drugs and medicaments	0.005	0.995	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.995	0.005
G60.3 Idiopathic progressive neuropathy	0.004	0.995	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.004	0.995	0.000
G60.1 Refsum's disease	0.004	0.995	0.000
K82.4 Cholesterolosis of gallbladder	0.004	0.996	0.000
H95.1 Other disorders following mastoidectomy	0.000	0.996	0.004
S92.31 Fracture of metatarsal bone (open)	0.004	0.996	0.000
D68.9 Coagulation defect, unspecified	0.004	0.996	0.000
K08 Other disorders of teeth and supporting structures	0.000	0.996	0.004
D68.1 Hereditary factor XI deficiency	0.004	0.996	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.004	0.996	0.000
E10.4 With neurological complications	0.004	0.996	0.000
R25.2 Cramp and spasm	0.004	0.996	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.000	0.996	0.004
N49.0 Inflammatory disorders of seminal vesicle	0.000	0.996	0.004
H72.0 Central perforation of tympanic membrane	0.000	0.996	0.004
D73 Diseases of spleen	0.004	0.996	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.004	0.996	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.004	0.996	0.000
H91 Other hearing loss	0.000	0.996	0.004
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.996	0.004
E06.3 Autoimmune thyroiditis	0.004	0.996	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.000	0.996	0.004
H65.3 Chronic mucoid otitis media	0.000	0.996	0.004
D68.0 Von Willebrand's disease	0.004	0.996	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.996	0.004
M62.82 Other specified disorders of muscle (Upper arm)	0.004	0.996	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.996	0.004
C18.6 Descending colon	0.004	0.996	0.000
M62.8 Other specified disorders of muscle	0.004	0.996	0.000
Z04.8 Examination and observation for other specified reasons	0.000	0.996	0.004
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.997	0.003
H91.3 Deaf mutism, not elsewhere classified	0.000	0.997	0.003
E83.5 Disorders of calcium metabolism	0.000	0.997	0.003
G70-G73 Diseases of myoneural junction and muscle	0.000	0.997	0.003
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.003	0.997	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.997	0.003
S92 Fracture of foot, except ankle	0.003	0.997	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.000	0.997	0.003
R23.4 Changes in skin texture	0.003	0.997	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.997	0.003
G63.8 Polyneuropathy in other diseases classified elsewhere	0.003	0.997	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.003	0.997	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.003	0.997	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.003	0.997	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.003	0.997	0.000
G63.1 Polyneuropathy in neoplastic disease	0.003	0.997	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
R63.4 Abnormal weight loss	0.003	0.997	0.000
H91.8 Other specified hearing loss	0.000	0.997	0.003
L27.0 Generalised skin eruption due to drugs and medicaments	0.003	0.997	0.000
D73.3 Abscess of spleen	0.003	0.997	0.000
D73.2 Chronic congestive splenomegaly	0.003	0.997	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.997	0.003
H57.1 Ocular pain	0.000	0.997	0.003
D68.4 Acquired coagulation factor deficiency	0.003	0.997	0.000
D73.9 Disease of spleen, unspecified	0.003	0.997	0.000
G60.0 Hereditary motor and sensory neuropathy	0.003	0.997	0.000
J04 Acute laryngitis and tracheitis	0.003	0.997	0.000
H72 Perforation of tympanic membrane	0.000	0.997	0.003
L27 Dermatitis due to substances taken internally	0.003	0.997	0.000
H65 Nonsuppurative otitis media	0.000	0.997	0.003
M62.88 Other specified disorders of muscle (Other)	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.997	0.003
H90.2 Conductive hearing loss, unspecified	0.000	0.997	0.003
K81.0 Acute cholecystitis	0.000	0.997	0.003
M62.86 Other specified disorders of muscle (Lower leg)	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.997	0.003
S92.4 Fracture of great toe	0.003	0.997	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.003	0.997	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.997	0.003
S92.2 Fracture of other tarsal bone(s)	0.003	0.997	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.997	0.003
M62.87 Other specified disorders of muscle (Ankle and foot)	0.003	0.997	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.997	0.003
G72 Other myopathies	0.000	0.997	0.003
E10.9 Without complications	0.003	0.997	0.000
H91.2 Sudden idiopathic hearing loss	0.000	0.997	0.003
G72.9 Myopathy, unspecified	0.000	0.997	0.003
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.003	0.997	0.000
G71 Primary disorders of muscles	0.000	0.997	0.003
D73.4 Cyst of spleen	0.003	0.997	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.997	0.003
S92.0 Fracture of calcaneus	0.003	0.997	0.000
H91.0 Ototoxic hearing loss	0.000	0.997	0.003
J04.1 Acute tracheitis	0.003	0.997	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.997	0.003
C48.0 Retroperitoneum	0.003	0.997	0.000
D73.1 Hypersplenism	0.003	0.997	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.997	0.003
M24.02 Loose body in joint (Upper arm)	0.003	0.997	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
K74.6 Other and unspecified cirrhosis of liver	0.000	0.997	0.003
S32.40 Fracture of acetabulum (closed)	0.000	0.997	0.003
C80.0 Malignant neoplasm, primary site unknown, so stated	0.003	0.997	0.000
K08.3 Retained dental root	0.000	0.997	0.003
H57 Other disorders of eye and adnexa	0.000	0.997	0.003
M24.07 Loose body in joint (Ankle and foot)	0.003	0.997	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.003	0.997	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.003	0.997	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.000	0.997	0.003
F06.5 Organic dissociative disorder	0.000	0.997	0.003
F06.4 Organic anxiety disorder	0.000	0.997	0.003
F06.3 Organic mood [affective] disorders	0.000	0.997	0.003
F06.2 Organic delusional [schizophrenia-like] disorder	0.000	0.997	0.003
F06.1 Organic catatonic disorder	0.000	0.997	0.003
F06.0 Organic hallucinosis	0.000	0.997	0.003
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.997	0.003
S92.9 Fracture of foot, unspecified	0.003	0.997	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.003	0.997	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.997	0.003
M62.83 Other specified disorders of muscle (Forearm)	0.003	0.997	0.000
S92.41 Fracture of great toe (open)	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.997	0.003
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.997	0.003
S92.01 Fracture of calcaneus (open)	0.003	0.997	0.000
M62 Other disorders of muscle	0.003	0.997	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.997	0.003
S92.40 Fracture of great toe (closed)	0.003	0.997	0.000
D68.6 Other Thrombophilia	0.002	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.997	0.003
H72.8 Other perforations of tympanic membrane	0.000	0.997	0.003
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.003	0.997	0.000
D68.5 Primary Thrombophilia	0.002	0.997	0.000
E06 Thyroiditis	0.003	0.997	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.000	0.997	0.002
R63 Symptoms and signs concerning food and fluid intake	0.003	0.997	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.997	0.002
J04.2 Acute laryngotracheitis	0.002	0.997	0.000
H91.1 Presbycusis	0.000	0.997	0.002
L27.9 Dermatitis due to unspecified substance taken internally	0.002	0.997	0.000
L27.8 Dermatitis due to other substances taken internally	0.002	0.997	0.000
G71.0 Muscular dystrophy	0.000	0.997	0.002
K59.8 Other specified functional intestinal disorders	0.000	0.997	0.003
S92.1 Fracture of talus	0.002	0.997	0.000
C18 Malignant neoplasm of colon	0.003	0.997	0.000
H57.8 Other specified disorders of eye and adnexa	0.000	0.998	0.002
S31.0 Open wound of lower back and pelvis	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
D73.8 Other diseases of spleen	0.002	0.998	0.000
L27.2 Dermatitis due to ingested food	0.002	0.998	0.000
M24.0 Loose body in joint	0.002	0.998	0.000
K76.6 Portal hypertension	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
G72.1 Alcoholic myopathy	0.000	0.998	0.002
G72.0 Drug-induced myopathy	0.000	0.998	0.002
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.998	0.002
G72.3 Periodic paralysis	0.000	0.998	0.002
G72.2 Myopathy due to other toxic agents	0.000	0.998	0.002
S31 Open wound of abdomen, lower back and pelvis	0.002	0.998	0.000
D68.8 Other specified coagulation defects	0.002	0.998	0.000
G71.9 Primary disorder of muscle, unspecified	0.000	0.998	0.002
G71.8 Other primary disorders of muscles	0.000	0.998	0.002
G71.2 Congenital myopathies	0.000	0.998	0.002
M62.1 Other rupture of muscle (nontraumatic)	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.998	0.002
E85.9 Amyloidosis, unspecified	0.000	0.998	0.002
R63.1 Polydipsia	0.002	0.998	0.000
R63.0 Anorexia	0.002	0.998	0.000
S31.1 Open wound of abdominal wall	0.002	0.998	0.000
M24.04 Loose body in joint (Hand)	0.002	0.998	0.000
D75.1 Secondary polycythaemia	0.002	0.998	0.000
M62.6 Muscle strain	0.002	0.998	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.998	0.002
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.998	0.002
D26.0 Cervix uteri	0.000	0.998	0.002
D73.5 Infarction of spleen	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.002	0.998	0.000
R63.5 Abnormal weight gain	0.002	0.998	0.000
E03 Other hypothyroidism	0.002	0.998	0.000
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.002	0.998	0.000
C18.9 Colon, unspecified	0.002	0.998	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.998	0.002
M62.0 Diastasis of muscle	0.002	0.998	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
H65.2 Chronic serous otitis media	0.000	0.998	0.002
S31.2 Open wound of penis	0.002	0.998	0.000
H65-H75 Diseases of middle ear and mastoid	0.000	0.998	0.002
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
I77.8 Other specified disorders of arteries and arterioles	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
Z48.9 Surgical follow-up care, unspecified	0.000	0.998	0.002
H72.1 Attic perforation of tympanic membrane	0.000	0.998	0.002
M62.4 Contracture of muscle	0.002	0.998	0.000
M62.3 Immobility syndrome (paraplegic)	0.002	0.998	0.000
M62.2 Ischaemic infarction of muscle	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
M87.9 Osteonecrosis, unspecified	0.000	0.998	0.002
S05.5 Penetrating wound of eyeball with foreign body	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.002	0.998	0.000
E06.4 Drug-induced thyroiditis	0.002	0.998	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.998	0.000
E06.1 Subacute thyroiditis	0.002	0.998	0.000
E06.0 Acute thyroiditis	0.002	0.998	0.000
G73.7 Myopathy other diseases classified elsewhere	0.000	0.998	0.002
G73.6 Myopathy in metabolic diseases	0.000	0.998	0.002
G73.5 Myopathy in endocrine diseases	0.000	0.998	0.002
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.000	0.998	0.002
G73.2 Other myasthenic syndromes in neoplastic disease	0.000	0.998	0.002
G73.1 Eaton-Lambert syndrome	0.000	0.998	0.002
R63.2 Polyphagia	0.002	0.998	0.000
Chapter VIII Diseases of the ear and mastoid process	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations