TreeWAS – Variant ID: rs16928705

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.112	0.888	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.109	0.891	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.102	0.898	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.099	0.901	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.098	0.902	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.096	0.904	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.083	0.917	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.081	0.919	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.077	0.922	0.000
H40.9 Glaucoma, unspecified	0.070	0.930	0.000
H40 Glaucoma	0.064	0.936	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.062	0.938	0.000
H40.8 Other glaucoma	0.062	0.938	0.000
H40.2 Primary angle-closure glaucoma	0.056	0.944	0.000
H40.5 Glaucoma secondary to other eye disorders	0.047	0.953	0.000
H40.6 Glaucoma secondary to drugs	0.046	0.954	0.000
H40.4 Glaucoma secondary to eye inflammation	0.046	0.954	0.000
H40.3 Glaucoma secondary to eye trauma	0.046	0.954	0.000
H40.0 Glaucoma suspect	0.046	0.954	0.000
H40.1 Primary open-angle glaucoma	0.042	0.958	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.036	0.964	0.000
H40-H42 Glaucoma	0.028	0.972	0.000
H42 Glaucoma in diseases classified elsewhere	0.020	0.980	0.000
S90-S99 Injuries to the ankle and foot	0.019	0.981	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.017	0.983	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.017	0.983	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.017	0.983	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.017	0.983	0.000
S90 Superficial injury of ankle and foot	0.017	0.983	0.000
S92 Fracture of foot, except ankle	0.016	0.984	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.016	0.984	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.016	0.984	0.000
S91 Open wound of ankle and foot	0.016	0.984	0.000
S91.1 Open wound of toe(s) without damage to nail	0.016	0.984	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.016	0.984	0.000
S00-S09 Injuries to the head	0.015	0.985	0.000
S93.0 Dislocation of ankle joint	0.015	0.985	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.015	0.985	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.015	0.985	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.014	0.985	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.014	0.985	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.015	0.985	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.015	0.985	0.000
C15.5 Lower third of oesophagus	0.000	0.985	0.015
S96 Injury of muscle and tendon at ankle and foot level	0.014	0.986	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.014	0.986	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.014	0.986	0.000
T00-T07 Injuries involving multiple body regions	0.014	0.986	0.000
S09 Other and unspecified injuries of head	0.014	0.986	0.000
C15.9 Oesophagus, unspecified	0.000	0.986	0.014
C15 Malignant neoplasm of oesophagus	0.000	0.986	0.014
S93.1 Dislocation of toe(s)	0.014	0.986	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.014	0.986	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.014	0.986	0.000
S05 Injury of eye and orbit	0.014	0.986	0.000
S20-S29 Injuries to the thorax	0.014	0.986	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.014	0.986	0.000
S98 Traumatic amputation of ankle and foot	0.013	0.986	0.000
S97 Crushing injury of ankle and foot	0.013	0.986	0.000
S95 Injury of blood vessels at ankle and foot level	0.013	0.986	0.000
S94 Injury of nerves at ankle and foot level	0.013	0.986	0.000
T86 Failure and rejection of transplanted organs and tissues	0.014	0.986	0.000
S92.3 Fracture of metatarsal bone	0.013	0.986	0.000
S01 Open wound of head	0.013	0.987	0.000
S09.9 Unspecified injury of head	0.013	0.987	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.013	0.987	0.000
S92.1 Fracture of talus	0.013	0.987	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.013	0.987	0.000
S92.5 Fracture of other toe	0.013	0.987	0.000
C15.4 Middle third of oesophagus	0.000	0.987	0.013
S92.4 Fracture of great toe	0.013	0.987	0.000
T00 Superficial injuries involving multiple body regions	0.013	0.987	0.000
T20 Burn and corrosion of head and neck	0.013	0.987	0.000
S90.8 Other superficial injuries of ankle and foot	0.013	0.987	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.013	0.987	0.000
T14 Injury of unspecified body region	0.013	0.987	0.000
S01.7 Multiple open wounds of head	0.013	0.987	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.013	0.987	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.013	0.987	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.013	0.987	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.013	0.987	0.000
S01.2 Open wound of nose	0.013	0.987	0.000
T45.0 Antiallergic and antiemetic drugs	0.012	0.987	0.000
S92.2 Fracture of other tarsal bone(s)	0.012	0.988	0.000
S93.4 Sprain and strain of ankle	0.012	0.988	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.012	0.988	0.000
S93.5 Sprain and strain of toe(s)	0.012	0.988	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.012	0.988	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.012	0.988	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.012	0.988	0.000
S05.8 Other injuries of eye and orbit	0.012	0.988	0.000
S50-S59 Injuries to the elbow and forearm	0.012	0.988	0.000
S90.0 Contusion of ankle	0.012	0.988	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.012	0.988	0.000
S90.3 Contusion of other and unspecified parts of foot	0.012	0.988	0.000
S90.2 Contusion of toe(s) with damage to nail	0.012	0.988	0.000
S90.1 Contusion of toe(s) without damage to nail	0.012	0.988	0.000
S92.7 Multiple fractures of foot	0.012	0.988	0.000
S06 Intracranial injury	0.012	0.988	0.000
S99 Other and unspecified injuries of ankle and foot	0.012	0.988	0.000
S92.9 Fracture of foot, unspecified	0.012	0.988	0.000
T81 Complications of procedures, not elsewhere classified	0.012	0.988	0.000
T17 Foreign body in respiratory tract	0.012	0.988	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.012	0.988	0.000
T33-T35 Frostbite	0.012	0.988	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.012	0.988	0.000
T43.9 Psychotropic drug, unspecified	0.012	0.988	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
T43.6 Psychostimulants with abuse potential	0.012	0.988	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.012	0.988	0.000
N30.9 Cystitis, unspecified	0.000	0.988	0.012
S91.7 Multiple open wounds of ankle and foot	0.012	0.988	0.000
S91.2 Open wound of toe(s) with damage to nail	0.012	0.988	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.012	0.988	0.000
T36 Poisoning by systemic antibiotics	0.012	0.988	0.000
S91.0 Open wound of ankle	0.012	0.988	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.012	0.988	0.000
T16 Foreign body in ear	0.012	0.988	0.000
T00.6 Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)	0.012	0.988	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.012	0.988	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.012	0.988	0.000
S01.4 Open wound of cheek and temporomandibular area	0.012	0.988	0.000
S06.9 Intracranial injury, unspecified	0.011	0.988	0.000
T86.0 Bone-marrow transplant rejection	0.011	0.988	0.000
S92.30 Fracture of metatarsal bone (closed)	0.011	0.988	0.000
T45.5 Anticoagulants	0.011	0.988	0.000
S21 Open wound of thorax	0.011	0.989	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.011	0.989	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.011	0.989	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.011	0.989	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.011	0.989	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.011	0.989	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.011	0.989	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.011	0.989	0.000
T44.0 Anticholinesterase agents	0.011	0.989	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.011	0.989	0.000
T81.7 Vascular complications following a procedure, not elsewhere classified	0.011	0.989	0.000
S05.9 Injury of eye and orbit, part unspecified	0.011	0.989	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.011	0.989	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.011	0.989	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.011	0.989	0.000
T14.0 Superficial injury of unspecified body region	0.011	0.989	0.000
S08 Traumatic amputation of part of head	0.011	0.989	0.000
S07 Crushing injury of head	0.011	0.989	0.000
S04 Injury of cranial nerves	0.011	0.989	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.011	0.989	0.000
T45.2 Vitamins, not elsewhere classified	0.011	0.989	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.011	0.989	0.000
T86.4 Liver transplant failure and rejection	0.011	0.989	0.000
T19 Foreign body in genito-urinary tract	0.011	0.989	0.000
T23 Burn and corrosion of wrist and hand	0.011	0.989	0.000
T20.2 Burn of second degree of head and neck	0.011	0.989	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.011	0.989	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.011	0.989	0.000
T20.1 Burn of first degree of head and neck	0.011	0.989	0.000
S92.10 Fracture of talus (closed)	0.011	0.989	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.011	0.989	0.000
T50.8 Diagnostic agents	0.011	0.989	0.000
T50.7 Analeptics and opioid receptor antagonists	0.011	0.989	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.011	0.989	0.000
T50.5 Appetite depressants	0.011	0.989	0.000
T50.4 Drugs affecting uric acid metabolism	0.011	0.989	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.011	0.989	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.011	0.989	0.000
T50.1 Loop [high-ceiling] diuretics	0.011	0.989	0.000
T50.0 Mineralocorticoids and their antagonists	0.011	0.989	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.011	0.989	0.000
T45.8 Other primarily systemic and haematological agents	0.011	0.989	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.011	0.989	0.000
T45.6 Fibrinolysis-affecting drugs	0.011	0.989	0.000
T45.4 Iron and its compounds	0.011	0.989	0.000
T45.3 Enzymes, not elsewhere classified	0.011	0.989	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.011	0.989	0.000
T14.1 Open wound of unspecified body region	0.011	0.989	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.011	0.989	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.989	0.011
T81.8 Other complications of procedures, not elsewhere classified	0.011	0.989	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.010	0.989	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.010	0.989	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.010	0.989	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.010	0.989	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.010	0.989	0.000
S92.51 Fracture of other toe (open)	0.010	0.989	0.000
T25 Burn and corrosion of ankle and foot	0.010	0.989	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.011	0.989	0.000
T15 Foreign body on external eye	0.010	0.989	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.010	0.989	0.000
T05 Traumatic amputations involving multiple body regions	0.010	0.989	0.000
T04 Crushing injuries involving multiple body regions	0.010	0.989	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.010	0.989	0.000
T02 Fractures involving multiple body regions	0.010	0.989	0.000
T01 Open wounds involving multiple body regions	0.010	0.989	0.000
T07 Unspecified multiple injuries	0.010	0.989	0.000
T11 Other injuries of upper limb, level unspecified	0.010	0.989	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.011	0.989	0.000
T66-T78 Other and unspecified effects of external causes	0.010	0.989	0.000
S09.7 Multiple injuries of head	0.010	0.989	0.000
S09.2 Traumatic rupture of ear drum	0.010	0.989	0.000
S09.1 Injury of muscle and tendon of head	0.010	0.989	0.000
S51 Open wound of forearm	0.010	0.990	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.010	0.990	0.000
S92.41 Fracture of great toe (open)	0.010	0.990	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.010	0.990	0.000
S27 Injury of other and unspecified intrathoracic organs	0.010	0.990	0.000
C15.8 Overlapping lesion of oesophagus	0.000	0.990	0.010
C15.2 Abdominal part of oesophagus	0.000	0.990	0.010
C15.1 Thoracic part of oesophagus	0.000	0.990	0.010
C15.0 Cervical part of oesophagus	0.000	0.990	0.010
T09 Other injuries of spine and trunk, level unspecified	0.010	0.990	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.010	0.990	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.010	0.990	0.000
T12 Fracture of lower limb, level unspecified	0.010	0.990	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.010	0.990	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.010	0.990	0.000
T10 Fracture of upper limb, level unspecified	0.010	0.990	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.010	0.990	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.010	0.990	0.000
T08 Fracture of spine, level unspecified	0.010	0.990	0.000
T21 Burn and corrosion of trunk	0.010	0.990	0.000
S29 Other and unspecified injuries of thorax	0.010	0.990	0.000
T38.9 Other and unspecified hormone antagonists	0.010	0.990	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.010	0.990	0.000
T38.7 Androgens and anabolic congeners	0.010	0.990	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.010	0.990	0.000
T38.5 Other oestrogens and progestogens	0.010	0.990	0.000
T38.4 Oral contraceptives	0.010	0.990	0.000
T38.2 Antithyroid drugs	0.010	0.990	0.000
T38.1 Thyroid hormones and substitutes	0.010	0.990	0.000
T38.0 Glucocorticoids and synthetic analogues	0.010	0.990	0.000
T18 Foreign body in alimentary tract	0.010	0.990	0.000
T17.2 Foreign body in pharynx	0.010	0.990	0.000
S56 Injury of muscle and tendon at forearm level	0.010	0.990	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.010	0.990	0.000
S01.0 Open wound of scalp	0.010	0.990	0.000
S05.7 Avulsion of eye	0.010	0.990	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.010	0.990	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.010	0.990	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.010	0.990	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.010	0.990	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.010	0.990	0.000
T00.8 Superficial injuries involving other combinations of body regions	0.010	0.990	0.000
S92.0 Fracture of calcaneus	0.010	0.990	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.010	0.990	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.010	0.990	0.000
S26 Injury of heart	0.010	0.990	0.000
S25 Injury of blood vessels of thorax	0.010	0.990	0.000
S24 Injury of nerves and spinal cord at thorax level	0.010	0.990	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.010	0.990	0.000
T46.1 Calcium-channel blockers	0.010	0.990	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.010	0.990	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.010	0.990	0.000
T47.7 Emetics	0.010	0.990	0.000
T47.6 Antidiarrhoeal drugs	0.010	0.990	0.000
T47.5 Digestants	0.010	0.990	0.000
T47.4 Other laxatives	0.010	0.990	0.000
T47.3 Saline and osmotic laxatives	0.010	0.990	0.000
T47.2 Stimulant laxatives	0.010	0.990	0.000
T47.0 Histamine H(2)-receptor antagonists	0.010	0.990	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.010	0.990	0.000
S94.8 Injury of other nerves at ankle and foot level	0.010	0.990	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.010	0.990	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.010	0.990	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.010	0.990	0.000
S94.1 Injury of medial plantar nerve	0.010	0.990	0.000
S94.0 Injury of lateral plantar nerve	0.010	0.990	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.010	0.990	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.010	0.990	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.010	0.990	0.000
S95.2 Injury of dorsal vein of foot	0.010	0.990	0.000
S95.1 Injury of plantar artery of foot	0.010	0.990	0.000
S95.0 Injury of dorsal artery of foot	0.010	0.990	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.010	0.990	0.000
S97.1 Crushing injury of toe(s)	0.010	0.990	0.000
S97.0 Crushing injury of ankle	0.010	0.990	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.010	0.990	0.000
S98.3 Traumatic amputation of other parts of foot	0.010	0.990	0.000
S98.2 Traumatic amputation of two or more toes	0.010	0.990	0.000
S98.1 Traumatic amputation of one toe	0.010	0.990	0.000
S98.0 Traumatic amputation of foot at ankle level	0.010	0.990	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.010	0.990	0.000
T86.3 Heart-lung transplant failure and rejection	0.010	0.990	0.000
T86.2 Heart transplant failure and rejection	0.010	0.990	0.000
S09.8 Other specified injuries of head	0.010	0.990	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.010	0.990	0.000
S92.31 Fracture of metatarsal bone (open)	0.010	0.990	0.000
T00.9 Multiple superficial injuries, unspecified	0.010	0.990	0.000
G90-G99 Other disorders of the nervous system	0.010	0.990	0.000
S01.5 Open wound of lip and oral cavity	0.010	0.990	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.010	0.990	0.000
C15.3 Upper third of oesophagus	0.000	0.990	0.010
T85.4 Mechanical complication of breast prosthesis and implant	0.010	0.990	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.010	0.990	0.000
S92.40 Fracture of great toe (closed)	0.010	0.990	0.000
T43.2 Other and unspecified antidepressants	0.010	0.990	0.000
T79-T79 Certain early complications of trauma	0.009	0.990	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.010	0.990	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.010	0.990	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.010	0.990	0.000
T46.7 Peripheral vasodilators	0.010	0.990	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.010	0.990	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.010	0.990	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.010	0.990	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.010	0.990	0.000
S92.11 Fracture of talus (open)	0.010	0.990	0.000
T40.2 Other opioids	0.010	0.990	0.000
S22.3 Fracture of rib	0.010	0.990	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.010	0.990	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.009	0.990	0.000
S92.50 Fracture of other toe (closed)	0.009	0.990	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.009	0.990	0.000
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.009	0.990	0.000
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.009	0.990	0.000
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.009	0.990	0.000
T00.0 Superficial injuries involving head with neck	0.009	0.990	0.000
T20.7 Corrosion of third degree of head and neck	0.009	0.990	0.000
T20.6 Corrosion of second degree of head and neck	0.009	0.990	0.000
T20.5 Corrosion of first degree of head and neck	0.009	0.990	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.009	0.990	0.000
T20.3 Burn of third degree of head and neck	0.009	0.990	0.000
T20.0 Burn of unspecified degree of head and neck	0.009	0.990	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.009	0.990	0.000
S01.3 Open wound of ear	0.009	0.990	0.000
S06.2 Diffuse brain injury	0.009	0.991	0.000
T14.2 Fracture of unspecified body region	0.009	0.991	0.000
T14.9 Injury, unspecified	0.009	0.991	0.000
T14.8 Other injuries of unspecified body region	0.009	0.991	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.009	0.991	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.009	0.991	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.009	0.991	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.009	0.991	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.009	0.991	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.009	0.991	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.009	0.991	0.000
T17.5 Foreign body in bronchus	0.009	0.991	0.000
S21.1 Open wound of front wall of thorax	0.009	0.991	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.009	0.991	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.009	0.991	0.000
T37.5 Antiviral drugs	0.009	0.991	0.000
T37.4 Anthelminthics	0.009	0.991	0.000
T37.3 Other antiprotozoal drugs	0.009	0.991	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.009	0.991	0.000
T37.1 Antimycobacterial drugs	0.009	0.991	0.000
T37.0 Sulphonamides	0.009	0.991	0.000
T41.5 Therapeutic gases	0.009	0.991	0.000
T41.4 Anaesthetic, unspecified	0.009	0.991	0.000
T41.3 Local anaesthetics	0.009	0.991	0.000
T41.2 Other and unspecified general anaesthetics	0.009	0.991	0.000
T41.1 Intravenous anaesthetics	0.009	0.991	0.000
T41.0 Inhaled anaesthetics	0.009	0.991	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.009	0.991	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.009	0.991	0.000
T48.5 Anti-common-cold drugs	0.009	0.991	0.000
T48.4 Expectorants	0.009	0.991	0.000
T48.3 Antitussives	0.009	0.991	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.009	0.991	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.009	0.991	0.000
T48.0 Oxytocic drugs	0.009	0.991	0.000
T49.9 Topical agent, unspecified	0.009	0.991	0.000
T49.8 Other topical agents	0.009	0.991	0.000
T49.7 Dental drugs, topically applied	0.009	0.991	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.009	0.991	0.000
T49.5 Ophthalmological drugs and preparations	0.009	0.991	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.009	0.991	0.000
T49.3 Emollients, demulcents and protectants	0.009	0.991	0.000
T49.2 Local astringents and local detergents	0.009	0.991	0.000
T49.1 Antipruritics	0.009	0.991	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.009	0.991	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.009	0.991	0.000
S51.0 Open wound of elbow	0.009	0.991	0.000
T13 Other injuries of lower limb, level unspecified	0.009	0.991	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.009	0.991	0.000
S54 Injury of nerves at forearm level	0.009	0.991	0.000
S93.40 Sprain of unspecified ligament of ankle	0.009	0.991	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.009	0.991	0.000
S01.9 Open wound of head, part unspecified	0.009	0.991	0.000
S92.70 Multiple fractures of foot (closed)	0.009	0.991	0.000
S58 Traumatic amputation of forearm	0.009	0.991	0.000
S57 Crushing injury of forearm	0.009	0.991	0.000
S55 Injury of blood vessels at forearm level	0.009	0.991	0.000
S92.71 Multiple fractures of foot (open)	0.009	0.991	0.000
S06.4 Epidural haemorrhage	0.009	0.991	0.000
S06.7 Intracranial injury with prolonged coma	0.009	0.991	0.000
S06.1 Traumatic cerebral oedema	0.009	0.991	0.000
S92.91 Fracture of foot, unspecified (open)	0.009	0.991	0.000
S92.90 Fracture of foot, unspecified (closed)	0.009	0.991	0.000
S21.9 Open wound of thorax, part unspecified	0.009	0.991	0.000
S99.8 Other specified injuries of ankle and foot	0.009	0.991	0.000
S99.7 Multiple injuries of ankle and foot	0.009	0.991	0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.009	0.991	0.000
S05.1 Contusion of eyeball and orbital tissues	0.009	0.991	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.009	0.991	0.000
T17.4 Foreign body in trachea	0.009	0.991	0.000
T17.3 Foreign body in larynx	0.009	0.991	0.000
T17.1 Foreign body in nostril	0.009	0.991	0.000
T17.0 Foreign body in nasal sinus	0.009	0.991	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.009	0.991	0.000
T40.8 Lysergide [LSD]	0.009	0.991	0.000
T40.7 Cannabis (derivatives)	0.009	0.991	0.000
T40.5 Cocaine	0.009	0.991	0.000
T40.3 Methadone	0.009	0.991	0.000
T40.1 Heroin	0.009	0.991	0.000
T40.0 Opium	0.009	0.991	0.000
S22.30 Fracture of rib (closed)	0.009	0.991	0.000
T28 Burn and corrosion of other internal organs	0.009	0.991	0.000
T27 Burn and corrosion of respiratory tract	0.009	0.991	0.000
T26 Burn and corrosion confined to eye and adnexa	0.009	0.991	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.009	0.991	0.000
T34 Frostbite with tissue necrosis	0.009	0.991	0.000
T33 Superficial frostbite	0.009	0.991	0.000
S21.2 Open wound of back wall of thorax	0.009	0.991	0.000
T19.2 Foreign body in vulva and vagina	0.009	0.991	0.000
S06.3 Focal brain injury	0.009	0.991	0.000
T36.9 Systemic antibiotic, unspecified	0.009	0.991	0.000
T36.8 Other systemic antibiotics	0.009	0.991	0.000
T36.7 Antifungal antibiotics, systemically used	0.009	0.991	0.000
T36.6 Rifamycins	0.009	0.991	0.000
T36.5 Aminoglycosides	0.009	0.991	0.000
T36.4 Tetracyclines	0.009	0.991	0.000
T36.3 Macrolides	0.009	0.991	0.000
T36.2 Chloramphenicol group	0.009	0.991	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.009	0.991	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.009	0.991	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.009	0.991	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.009	0.991	0.000
T42.3 Barbiturates	0.009	0.991	0.000
T42.2 Succinimides and oxazolidinediones	0.009	0.991	0.000
T42.0 Hydantoin derivatives	0.009	0.991	0.000
S20 Superficial injury of thorax	0.009	0.991	0.000
S22.2 Fracture of sternum	0.009	0.991	0.000
G93.4 Encephalopathy, unspecified	0.009	0.991	0.000
S06.8 Other intracranial injuries	0.009	0.991	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.009	0.991	0.000
T23.2 Burn of second degree of wrist and hand	0.008	0.991	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.008	0.991	0.000
G96 Other disorders of central nervous system	0.009	0.991	0.000
S59 Other and unspecified injuries of forearm	0.008	0.991	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.008	0.991	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.008	0.991	0.000
S27.3 Other injuries of lung	0.008	0.991	0.000
S21.8 Open wound of other parts of thorax	0.008	0.991	0.000
S21.7 Multiple open wounds of thoracic wall	0.008	0.991	0.000
S21.0 Open wound of breast	0.008	0.991	0.000
T87 Complications peculiar to reattachment and amputation	0.008	0.992	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.008	0.992	0.000
S64 Injury of nerves at wrist and hand level	0.008	0.992	0.000
T32 Corrosions classified according to extent of body surface involved	0.008	0.992	0.000
T30 Burn and corrosion, body region unspecified	0.008	0.992	0.000
T29 Burns and corrosions of multiple body regions	0.008	0.992	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.008	0.992	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.008	0.992	0.000
S91.3 Open wound of other parts of foot	0.008	0.992	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.008	0.992	0.000
S03.4 Sprain and strain of jaw	0.008	0.992	0.000
S03.3 Dislocation of other and unspecified parts of head	0.008	0.992	0.000
S03.2 Dislocation of tooth	0.008	0.992	0.000
S03.1 Dislocation of septal cartilage of nose	0.008	0.992	0.000
S03.0 Dislocation of jaw	0.008	0.992	0.000
S04.9 Injury of unspecified cranial nerve	0.008	0.992	0.000
S04.8 Injury of other cranial nerves	0.008	0.992	0.000
S04.7 Injury of accessory nerve	0.008	0.992	0.000
S04.6 Injury of acoustic nerve	0.008	0.992	0.000
S04.5 Injury of facial nerve	0.008	0.992	0.000
S04.4 Injury of abducent nerve	0.008	0.992	0.000
S04.3 Injury of trigeminal nerve	0.008	0.992	0.000
S04.2 Injury of trochlear nerve	0.008	0.992	0.000
S04.1 Injury of oculomotor nerve	0.008	0.992	0.000
S04.0 Injury of optic nerve and pathways	0.008	0.992	0.000
S07.9 Crushing injury of head, part unspecified	0.008	0.992	0.000
S07.8 Crushing injury of other parts of head	0.008	0.992	0.000
S07.1 Crushing injury of skull	0.008	0.992	0.000
S07.0 Crushing injury of face	0.008	0.992	0.000
S08.9 Traumatic amputation of unspecified part of head	0.008	0.992	0.000
S08.8 Traumatic amputation of other parts of head	0.008	0.992	0.000
S08.1 Traumatic amputation of ear	0.008	0.992	0.000
S08.0 Avulsion of scalp	0.008	0.992	0.000
S22.5 Flail chest	0.008	0.992	0.000
S51.9 Open wound of forearm, part unspecified	0.008	0.992	0.000
G91 Hydrocephalus	0.008	0.992	0.000
T19.9 Foreign body in genito-urinary tract, part unspecified	0.008	0.992	0.000
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.008	0.992	0.000
T19.3 Foreign body in uterus [any part]	0.008	0.992	0.000
T19.1 Foreign body in bladder	0.008	0.992	0.000
T19.0 Foreign body in urethra	0.008	0.992	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.008	0.992	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.008	0.992	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.008	0.992	0.000
T78 Adverse effects, not elsewhere classified	0.008	0.992	0.000
T23.7 Corrosion of third degree of wrist and hand	0.008	0.992	0.000
T23.6 Corrosion of second degree of wrist and hand	0.008	0.992	0.000
T23.5 Corrosion of first degree of wrist and hand	0.008	0.992	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.008	0.992	0.000
T23.3 Burn of third degree of wrist and hand	0.008	0.992	0.000
T23.1 Burn of first degree of wrist and hand	0.008	0.992	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.008	0.992	0.000
S52 Fracture of forearm	0.008	0.992	0.000
S60-S69 Injuries to the wrist and hand	0.008	0.992	0.000
G93 Other disorders of brain	0.008	0.992	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.008	0.992	0.000
S22.9 Fracture of bony thorax, part unspecified	0.008	0.992	0.000
S22.8 Fracture of other parts of bony thorax	0.008	0.992	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations