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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs169496
log Bayes Factor = 15.2802
Chromosome 6   position 32,052,983  (GRCh37) Explore rs169496 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.004 0.996
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.005 0.995
E10.3 With ophthalmic complications
0.000 0.010 0.990
E65-E68 Obesity and other hyperalimentation
0.000 0.012 0.988
E11.3 With ophthalmic complications
0.000 0.016 0.984
E10.1 With ketoacidosis
0.000 0.018 0.982
E66 Obesity
0.000 0.019 0.981
E66.8 Other obesity
0.000 0.032 0.968
E14 Unspecified diabetes mellitus
0.000 0.059 0.941
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.072 0.928
M06 Other rheumatoid arthritis
0.000 0.097 0.903
E66.9 Obesity, unspecified
0.000 0.101 0.899
E14.9 Without complications
0.000 0.110 0.890
E10.5 With peripheral circulatory complications
0.000 0.112 0.888
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.120 0.880
E11.5 With peripheral circulatory complications
0.000 0.135 0.865
E11.9 Without complications
0.000 0.139 0.861
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.151 0.849
E10.4 With neurological complications
0.000 0.164 0.836
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.165 0.835
E11.4 With neurological complications
0.000 0.169 0.831
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.175 0.825
E10.2 With renal complications
0.000 0.186 0.814
E05.9 Thyrotoxicosis, unspecified
0.000 0.199 0.801
M05-M14 Inflammatory polyarthropathies
0.000 0.211 0.789
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.213 0.787
E11.2 With renal complications
0.000 0.215 0.785
E06 Thyroiditis
0.000 0.227 0.773
M05 Seropositive rheumatoid arthritis
0.000 0.232 0.768
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.246 0.754
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.247 0.753
M06.0 Seronegative rheumatoid arthritis
0.000 0.255 0.745
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.266 0.734
M06.3 Rheumatoid nodule
0.000 0.267 0.733
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.3 With ophthalmic complications
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.716
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.716
E11.7 With multiple complications
0.000 0.286 0.714
E11.1 With ketoacidosis
0.000 0.289 0.711
E50-E64 Other nutritional deficiencies
0.000 0.289 0.711
E67 Other hyperalimentation
0.000 0.291 0.709
E68 Sequelae of hyperalimentation
0.000 0.291 0.709
E66.1 Drug-induced obesity
0.000 0.297 0.703
E66.0 Obesity due to excess calories
0.000 0.297 0.703
E65 Localised adiposity
0.000 0.304 0.696
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.314 0.686
E11.8 With unspecified complications
0.000 0.325 0.675
E14.8 With unspecified complications
0.000 0.325 0.674
E14.7 With multiple complications
0.000 0.325 0.674
E14.6 With other specified complications
0.000 0.325 0.674
E14.5 With peripheral circulatory complications
0.000 0.325 0.674
E14.4 With neurological complications
0.000 0.325 0.674
E14.2 Withrenal complications
0.000 0.325 0.674
E14.1 With ketoacidosis
0.000 0.325 0.674
E14.0 With coma
0.000 0.325 0.674
E05.8 Other thyrotoxicosis
0.000 0.334 0.665
E05.5 Thyroid crisis or storm
0.000 0.334 0.665
E05.4 Thyrotoxicosis factitia
0.000 0.334 0.665
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.334 0.665
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.334 0.665
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.337 0.663
E40-E46 Malnutrition
0.000 0.344 0.656
E11.6 With other specified complications
0.000 0.350 0.650
M06.8 Other specified rheumatoid arthritis
0.000 0.352 0.647
M06.2 Rheumatoid bursitis
0.000 0.352 0.647
M06.1 Adult-onset Still's disease
0.000 0.352 0.647
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.359 0.641
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.370 0.630
E06.3 Autoimmune thyroiditis
0.000 0.372 0.628
M10 Gout
0.000 0.380 0.620
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.386 0.614
M06.34 Rheumatoid nodule (Hand)
0.000 0.389 0.611
M14 Arthropathies in other diseases classified elsewhere
0.000 0.392 0.608
E07 Other disorders of thyroid
0.000 0.395 0.605
M13 Other arthritis
0.000 0.401 0.599
E20-E35 Disorders of other endocrine glands
0.000 0.413 0.587
E61 Deficiency of other nutrient elements
0.000 0.418 0.581
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.422 0.578
M12 Other specific arthropathies
0.000 0.434 0.565
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.434 0.565
M08 Juvenile arthritis
0.000 0.434 0.565
E11.0 With coma
0.000 0.436 0.564
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.437 0.563
E13 Other specified diabetes mellitus
0.000 0.442 0.558
E03.8 Other specified hypothyroidism
0.000 0.443 0.556
E06.5 Other chronic thyroiditis
0.000 0.446 0.554
E06.4 Drug-induced thyroiditis
0.000 0.446 0.554
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.446 0.554
E06.1 Subacute thyroiditis
0.000 0.446 0.554
E06.0 Acute thyroiditis
0.000 0.446 0.554
M05.8 Other seropositive rheumatoid arthritis
0.000 0.449 0.551
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.449 0.551
M05.2 Rheumatoid vasculitis
0.000 0.449 0.551
M05.1 Rheumatoid lung disease
0.000 0.449 0.551
M05.0 Felty's syndrome
0.000 0.449 0.551
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.460 0.540
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.460 0.540
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.460 0.540
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.460 0.540
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.460 0.540
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.460 0.540
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.460 0.540
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.460 0.540
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.465 0.534
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.465 0.534
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.465 0.534
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.465 0.534
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.465 0.534
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.465 0.534
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.465 0.534
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.465 0.534
E06.9 Thyroiditis, unspecified
0.000 0.473 0.527
M06.4 Inflammatory polyarthropathy
0.000 0.473 0.527
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.474 0.526
M06.38 Rheumatoid nodule (Other)
0.000 0.474 0.526
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.474 0.526
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.474 0.526
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.474 0.526
M06.33 Rheumatoid nodule (Forearm)
0.000 0.474 0.526
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.474 0.526
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.474 0.526
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.474 0.526
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.490 0.509
E63 Other nutritional deficiencies
0.000 0.490 0.509
E56 Other vitamin deficiencies
0.000 0.490 0.509
E51 Thiamine deficiency
0.000 0.490 0.509
E50 Vitamin A deficiency
0.000 0.490 0.509
E60 Dietary zinc deficiency
0.000 0.490 0.509
E59 Dietary selenium deficiency
0.000 0.490 0.509
E58 Dietary calcium deficiency
0.000 0.490 0.509
E54 Ascorbic acid deficiency
0.000 0.490 0.509
E52 Niacin deficiency [pellagra]
0.000 0.490 0.509
E67.8 Other specified hyperalimentation
0.000 0.492 0.508
E67.3 Hypervitaminosis D
0.000 0.492 0.508
E67.2 Megavitamin-B6 syndrome
0.000 0.492 0.508
E67.1 Hypercarotenaemia
0.000 0.492 0.508
E67.0 Hypervitaminosis A
0.000 0.492 0.508
E53 Deficiency of other B group vitamins
0.000 0.499 0.501
M10.9 Gout, unspecified
0.000 0.500 0.500
M13.0 Polyarthritis, unspecified
0.000 0.505 0.495
E61.1 Iron deficiency
0.000 0.511 0.489
E27 Other disorders of adrenal gland
0.000 0.518 0.481
M14.6 Neuropathic arthropathy
0.000 0.522 0.478
E15 Nondiabetic hypoglycaemic coma
0.000 0.524 0.475
M11 Other crystal arthropathies
0.000 0.526 0.473
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.530 0.470
E45 Retarded development following protein-energy malnutrition
0.000 0.530 0.470
E43 Unspecified severe protein-energy malnutrition
0.000 0.530 0.470
E42 Marasmic kwashiorkor
0.000 0.530 0.470
E41 Nutritional marasmus
0.000 0.530 0.470
E40 Kwashiorkor
0.000 0.530 0.470
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.536 0.464
M06.18 Adult-onset Still's disease (Other)
0.000 0.536 0.464
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.536 0.464
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.536 0.464
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.536 0.464
M06.14 Adult-onset Still's disease (Hand)
0.000 0.536 0.464
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.536 0.464
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.536 0.464
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.536 0.464
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.536 0.464
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.536 0.464
M06.28 Rheumatoid bursitis (Other)
0.000 0.536 0.464
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.536 0.464
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.536 0.464
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.536 0.464
M06.24 Rheumatoid bursitis (Hand)
0.000 0.536 0.464
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.536 0.464
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.536 0.464
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.536 0.464
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.536 0.464
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.536 0.464
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.536 0.464
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.536 0.464
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.536 0.464
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.536 0.464
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.536 0.464
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.536 0.464
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.536 0.464
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.536 0.464
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.536 0.464
M10.97 Gout, unspecified (Ankle and foot)
0.000 0.538 0.462
M07 Psoriatic and enteropathic arthropathies
0.000 0.548 0.452
E27.1 Primary adrenocortical insufficiency
0.000 0.554 0.446
M10.4 Other secondary gout
0.000 0.555 0.445
M10.3 Gout due to impairment of renal function
0.000 0.555 0.445
M10.2 Drug-induced gout
0.000 0.555 0.445
M10.1 Lead-induced gout
0.000 0.555 0.445
M10.0 Idiopathic gout
0.000 0.555 0.445
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.564 0.436
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.564 0.436
M14.4 Arthropathy in amyloidosis
0.000 0.564 0.436
M14.3 Lipoid dermatoarthritis
0.000 0.564 0.436
M14.2 Diabetic arthropathy
0.000 0.564 0.436
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.564 0.436
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.564 0.436
E07.1 Dyshormogenetic goitre
0.000 0.566 0.433
E07.0 Hypersecretion of calcitonin
0.000 0.566 0.433
M13.8 Other specified arthritis
0.000 0.570 0.429
M13.1 Monoarthritis, not elsewhere classified
0.000 0.570 0.429
E28 Ovarian dysfunction
0.000 0.571 0.429
M13.00 Polyarthritis, unspecified (Multiple sites)
0.000 0.572 0.427
E23 Hypofunction and other disorders of pituitary gland
0.000 0.576 0.424
E07.8 Other specified disorders of thyroid
0.000 0.577 0.423
E16 Other disorders of pancreatic internal secretion
0.000 0.578 0.422
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.579 0.421
E32 Diseases of thymus
0.000 0.579 0.421
E31 Polyglandular dysfunction
0.000 0.579 0.421
E30 Disorders of puberty, not elsewhere classified
0.000 0.579 0.421
E25 Adrenogenital disorders
0.000 0.579 0.421
E20 Hypoparathyroidism
0.000 0.579 0.421
E61.9 Deficiency of nutrient element, unspecified
0.000 0.583 0.417
E61.8 Deficiency of other specified nutrient elements
0.000 0.583 0.417
E61.7 Deficiency of multiple nutrient elements
0.000 0.583 0.417
E61.6 Vanadium deficiency
0.000 0.583 0.417
E61.5 Molybdenum deficiency
0.000 0.583 0.417
E61.4 Chromium deficiency
0.000 0.583 0.417
E61.3 Manganese deficiency
0.000 0.583 0.417
E61.2 Magnesium deficiency
0.000 0.583 0.417
E61.0 Copper deficiency
0.000 0.583 0.417
E34 Other endocrine disorders
0.000 0.588 0.412
E29 Testicular dysfunction
0.000 0.588 0.412
E46 Unspecified protein-energy malnutrition
0.000 0.591 0.409
M08.9 Juvenile arthritis, unspecified
0.000 0.594 0.405
M08.8 Other juvenile arthritis
0.000 0.594 0.405
M08.4 Pauciarticular juvenile arthritis
0.000 0.594 0.405
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.594 0.405
M08.2 Juvenile arthritis with systemic onset
0.000 0.594 0.405
M08.1 Juvenile ankylosing spondylitis
0.000 0.594 0.405
M08.0 Juvenile rheumatoid arthritis
0.000 0.594 0.405
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.594 0.405
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.594 0.405
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.594 0.405
M09.0 Juvenile arthritis in psoriasis
0.000 0.594 0.405
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.594 0.405
M12.5 Traumatic arthropathy
0.000 0.594 0.405
M12.4 Intermittent hydrarthrosis
0.000 0.594 0.405
M12.3 Palindromic rheumatism
0.000 0.594 0.405
M12.2 Villonodular synovitis (pigmented)
0.000 0.594 0.405
M12.1 Kaschin-Beck disease
0.000 0.594 0.405
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.594 0.405
E55 Vitamin D deficiency
0.000 0.599 0.401
E13.8 With unspecified complications
0.000 0.599 0.400
E13.7 With multiple complications
0.000 0.599 0.400
E13.6 With other specified complications
0.000 0.599 0.400
E13.5 With peripheral circulatory complications
0.000 0.599 0.400
E13.4 With neurological complications
0.000 0.599 0.400
E13.3 With ophthalmic complications
0.000 0.599 0.400
E13.2 With renal complications
0.000 0.599 0.400
E13.1 With ketoacidosis
0.000 0.599 0.400
E13.0 With coma
0.000 0.599 0.400
E53.8 Deficiency of other specified B group vitamins
0.000 0.602 0.397
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.604 0.396
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.001 0.604 0.395
M05.09 Felty's syndrome (Site unspecified)
0.000 0.605 0.395
M05.08 Felty's syndrome (Other)
0.000 0.605 0.395
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.605 0.395
M05.06 Felty's syndrome (Lower leg)
0.000 0.605 0.395
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.605 0.395
M05.04 Felty's syndrome (Hand)
0.000 0.605 0.395
M05.03 Felty's syndrome (Forearm)
0.000 0.605 0.395
M05.02 Felty's syndrome (Upper arm)
0.000 0.605 0.395
M05.01 Felty's syndrome (Shoulder region)
0.000 0.605 0.395
M05.00 Felty's syndrome (Multiple sites)
0.000 0.605 0.395
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.605 0.395
M05.18 Rheumatoid lung disease (Other)
0.000 0.605 0.395
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.605 0.395
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.605 0.395
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.605 0.395
M05.14 Rheumatoid lung disease (Hand)
0.000 0.605 0.395
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.605 0.395
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.605 0.395
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.605 0.395
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.605 0.395
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.605 0.395
M05.28 Rheumatoid vasculitis (Other)
0.000 0.605 0.395
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.605 0.395
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.605 0.395
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.605 0.395
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.605 0.395
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.605 0.395
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.605 0.395
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.605 0.395
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.605 0.395
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.605 0.395
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.605 0.395
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.605 0.395
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.605 0.395
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.605 0.395
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.605 0.395
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.605 0.395
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.605 0.395
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.605 0.395
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.605 0.395
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.605 0.395
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.605 0.395
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.605 0.395
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.605 0.395
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.605 0.395
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.605 0.395
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.605 0.395
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.605 0.395
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.605 0.395
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.605 0.395
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.607 0.392
E26 Hyperaldosteronism
0.000 0.621 0.378
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.622 0.378
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.622 0.378
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.622 0.378
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.622 0.378
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.622 0.378
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.622 0.378
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.622 0.378
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.622 0.378
M10.96 Gout, unspecified (Lower leg)
0.000 0.622 0.378
M13.9 Arthritis, unspecified
0.000 0.622 0.378
E50.9 Vitamin A deficiency, unspecified
0.000 0.634 0.365
E50.8 Other manifestations of vitamin A deficiency
0.000 0.634 0.365
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.634 0.365
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.634 0.365
E50.5 Vitamin A deficiency with night blindness
0.000 0.634 0.365
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.634 0.365
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.634 0.365
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.634 0.365
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.634 0.365
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.634 0.365
E51.9 Thiamine deficiency, unspecified
0.000 0.634 0.365
E51.8 Other manifestations of thiamine deficiency
0.000 0.634 0.365
E51.2 Wernicke's encephalopathy
0.000 0.634 0.365
E51.1 Beriberi
0.000 0.634 0.365
E56.9 Vitamin deficiency, unspecified
0.000 0.634 0.365
E56.8 Deficiency of other vitamins
0.000 0.634 0.365
E56.1 Deficiency of vitamin K
0.000 0.634 0.365
E56.0 Deficiency of vitamin E
0.000 0.634 0.365
E63.9 Nutritional deficiency, unspecified
0.000 0.634 0.365
E63.8 Other specified nutritional deficiencies
0.000 0.634 0.365
E63.1 Imbalance of constituents of food intake
0.000 0.634 0.365
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.634 0.365
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.634 0.365
E64.8 Sequelae of other nutritional deficiencies
0.000 0.634 0.365
E64.3 Sequelae of rickets
0.000 0.634 0.365
E64.2 Sequelae of vitamin C deficiency
0.000 0.634 0.365
E64.1 Sequelae of vitamin A deficiency
0.000 0.634 0.365
E64.0 Sequelae of protein-energy malnutrition
0.000 0.634 0.365
E24 Cushing's syndrome
0.000 0.640 0.360
E53.1 Pyridoxine deficiency
0.000 0.640 0.359
E53.0 Riboflavin deficiency
0.000 0.640 0.359
E22 Hyperfunction of pituitary gland
0.000 0.641 0.359
M10.98 Gout, unspecified (Other)
0.000 0.642 0.358
M10.95 Gout, unspecified (Pelvic region and thigh)
0.000 0.642 0.358
M10.93 Gout, unspecified (Forearm)
0.000 0.642 0.358
M10.92 Gout, unspecified (Upper arm)
0.000 0.642 0.358
M10.91 Gout, unspecified (Shoulder region)
0.000 0.642 0.358
M10.90 Gout, unspecified (Multiple sites)
0.000 0.642 0.358
E27.8 Other specified disorders of adrenal gland
0.000 0.642 0.358
M10.94 Gout, unspecified (Hand)
0.000 0.645 0.355
M13.08 Polyarthritis, unspecified (Other)
0.000 0.645 0.355
M13.07 Polyarthritis, unspecified (Ankle and foot)
0.000 0.645 0.355
M13.06 Polyarthritis, unspecified (Lower leg)
0.000 0.645 0.355
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)
0.000 0.645 0.355
M13.04 Polyarthritis, unspecified (Hand)
0.000 0.645 0.355
M13.03 Polyarthritis, unspecified (Forearm)
0.000 0.645 0.355
M13.02 Polyarthritis, unspecified (Upper arm)
0.000 0.645 0.355
M13.01 Polyarthritis, unspecified (Shoulder region)
0.000 0.645 0.355
M13.94 Arthritis, unspecified (Hand)
0.000 0.654 0.346
E27.5 Adrenomedullary hyperfunction
0.000 0.655 0.345
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.655 0.345
E27.2 Addisonian crisis
0.000 0.655 0.345
E27.0 Other adrenocortical overactivity
0.000 0.655 0.345
M13.09 Polyarthritis, unspecified (Site unspecified)
0.000 0.660 0.340
M11.9 Crystal arthropathy, unspecified
0.000 0.660 0.339
M11.8 Other specified crystal arthropathies
0.000 0.660 0.339
M11.1 Familial chondrocalcinosis
0.000 0.660 0.339
M11.0 Hydroxyapatite deposition disease
0.000 0.660 0.339
E07.9 Disorder of thyroid, unspecified
0.000 0.662 0.338
E44.1 Mild protein-energy malnutrition
0.000 0.663 0.337
E44.0 Moderate protein-energy malnutrition
0.000 0.663 0.337
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.663 0.337
E23.2 Diabetes insipidus
0.000 0.665 0.335
M07.6 Other enteropathic arthropathies
0.000 0.676 0.324
M07.5 Arthropathy in ulcerative colitis
0.000 0.676 0.324
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.676 0.324
M07.2 Psoriatic spondylitis
0.000 0.676 0.324
M07.1 Arthritis mutilans
0.000 0.676 0.324
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.676 0.324
M10.09 Idiopathic gout (Site unspecified)
0.000 0.681 0.319
M10.08 Idiopathic gout (Other)
0.000 0.681 0.319
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.681 0.319
M10.06 Idiopathic gout (Lower leg)
0.000 0.681 0.319
M10.05 Idiopathic gout (Pelvic region and thigh)
0.000 0.681 0.319
M10.04 Idiopathic gout (Hand)
0.000 0.681 0.319
M10.03 Idiopathic gout (Forearm)
0.000 0.681 0.319
M10.02 Idiopathic gout (Upper arm)
0.000 0.681 0.319
M10.01 Idiopathic gout (Shoulder region)
0.000 0.681 0.319
M10.00 Idiopathic gout (Multiple sites)
0.000 0.681 0.319
M10.19 Lead-induced gout (Site unspecified)
0.000 0.681 0.319
M10.18 Lead-induced gout (Other)
0.000 0.681 0.319
M10.17 Lead-induced gout (Ankle and foot)
0.000 0.681 0.319
M10.16 Lead-induced gout (Lower leg)
0.000 0.681 0.319
M10.15 Lead-induced gout (Pelvic region and thigh)
0.000 0.681 0.319
M10.14 Lead-induced gout (Hand)
0.000 0.681 0.319
M10.13 Lead-induced gout (Forearm)
0.000 0.681 0.319
M10.12 Lead-induced gout (Upper arm)
0.000 0.681 0.319
M10.11 Lead-induced gout (Shoulder region)
0.000 0.681 0.319
M10.10 Lead-induced gout (Multiple sites)
0.000 0.681 0.319
M10.29 Drug-induced gout (Site unspecified)
0.000 0.681 0.319
M10.28 Drug-induced gout (Other)
0.000 0.681 0.319
M10.27 Drug-induced gout (Ankle and foot)
0.000 0.681 0.319
M10.26 Drug-induced gout (Lower leg)
0.000 0.681 0.319
M10.25 Drug-induced gout (Pelvic region and thigh)
0.000 0.681 0.319
M10.24 Drug-induced gout (Hand)
0.000 0.681 0.319
M10.23 Drug-induced gout (Forearm)
0.000 0.681 0.319
M10.22 Drug-induced gout (Upper arm)
0.000 0.681 0.319
M10.21 Drug-induced gout (Shoulder region)
0.000 0.681 0.319
M10.20 Drug-induced gout (Multiple sites)
0.000 0.681 0.319
M10.39 Gout due to impairment of renal function (Site unspecified)
0.000 0.681 0.319
M10.38 Gout due to impairment of renal function (Other)
0.000 0.681 0.319
M10.37 Gout due to impairment of renal function (Ankle and foot)
0.000 0.681 0.319
M10.36 Gout due to impairment of renal function (Lower leg)
0.000 0.681 0.319
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)
0.000 0.681 0.319
M10.34 Gout due to impairment of renal function (Hand)
0.000 0.681 0.319
M10.33 Gout due to impairment of renal function (Forearm)
0.000 0.681 0.319
M10.32 Gout due to impairment of renal function (Upper arm)
0.000 0.681 0.319
M10.31 Gout due to impairment of renal function (Shoulder region)
0.000 0.681 0.319
M10.30 Gout due to impairment of renal function (Multiple sites)
0.000 0.681 0.319
M10.49 Other secondary gout (Site unspecified)
0.000 0.681 0.319
M10.48 Other secondary gout (Other)
0.000 0.681 0.319
M10.47 Other secondary gout (Ankle and foot)
0.000 0.681 0.319
M10.46 Other secondary gout (Lower leg)
0.000 0.681 0.319
M10.45 Other secondary gout (Pelvic region and thigh)
0.000 0.681 0.319
M10.44 Other secondary gout (Hand)
0.000 0.681 0.319
M10.43 Other secondary gout (Forearm)
0.000 0.681 0.319
M10.42 Other secondary gout (Upper arm)
0.000 0.681 0.319
M10.41 Other secondary gout (Shoulder region)
0.000 0.681 0.319
M10.40 Other secondary gout (Multiple sites)
0.000 0.681 0.319
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.682 0.318
E28.2 Polycystic ovarian syndrome
0.000 0.685 0.315
M13.19 Monoarthritis, not elsewhere classified (Site unspecified)
0.000 0.692 0.308
M13.18 Monoarthritis, not elsewhere classified (Other)
0.000 0.692 0.308
M13.17 Monoarthritis, not elsewhere classified (Ankle and foot)
0.000 0.692 0.308
M13.16 Monoarthritis, not elsewhere classified (Lower leg)
0.000 0.692 0.308
M13.15 Monoarthritis, not elsewhere classified (Pelvic region and thigh)
0.000 0.692 0.308
M13.14 Monoarthritis, not elsewhere classified (Hand)
0.000 0.692 0.308
M13.13 Monoarthritis, not elsewhere classified (Forearm)
0.000 0.692 0.308
M13.12 Monoarthritis, not elsewhere classified (Upper arm)
0.000 0.692 0.308
M13.11 Monoarthritis, not elsewhere classified (Shoulder region)
0.000 0.692 0.308
M13.10 Monoarthritis, not elsewhere classified (Multiple sites)
0.000 0.692 0.308
M13.89 Other specified arthritis (Site unspecified)
0.000 0.692 0.308
M13.88 Other specified arthritis (Other)
0.000 0.692 0.308
M13.87 Other specified arthritis (Ankle and foot)
0.000 0.692 0.308
M13.86 Other specified arthritis (Lower leg)
0.000 0.692 0.308
M13.85 Other specified arthritis (Pelvic region and thigh)
0.000 0.692 0.308
M13.84 Other specified arthritis (Hand)
0.000 0.692 0.308
M13.83 Other specified arthritis (Forearm)
0.000 0.692 0.308
M13.82 Other specified arthritis (Upper arm)
0.000 0.692 0.308
M13.81 Other specified arthritis (Shoulder region)
0.000 0.692 0.308
M13.80 Other specified arthritis (Multiple sites)
0.000 0.692 0.308
E28.9 Ovarian dysfunction, unspecified
0.000 0.693 0.307
E28.8 Other ovarian dysfunction
0.000 0.693 0.307
E28.3 Primary ovarian failure
0.000 0.693 0.307

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

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