TreeWAS – Variant ID: rs16953998

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter X Diseases of the respiratory system	1.000	0.000
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
E10-E14 Diabetes mellitus	0.998	0.002
J40-J47 Chronic lower respiratory diseases	0.997	0.003
J09-J18 Influenza and pneumonia	0.997	0.003
E11 Non-insulin-dependent diabetes mellitus	0.995	0.005
Chapter VII Diseases of the eye and adnexa	0.994	0.006
E11.9 Without complications	0.993	0.007
J18 Pneumonia, organism unspecified	0.990	0.010
Chapter XI Diseases of the digestive system	0.985	0.015
Chapter II Neoplasms	0.984	0.016
Chapter V Mental and behavioural disorders	0.984	0.016
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.984	0.016
Chapter I Certain infectious and parasitic diseases	0.983	0.017
J18.9 Pneumonia, unspecified	0.983	0.017
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.981	0.019
J43 Emphysema	0.977	0.023
J80-J84 Other respiratory diseases principally affecting the interstitium	0.966	0.034
H02 Other disorders of eyelid	0.966	0.034
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.964	0.036
Chapter XX External causes of morbidity and mortality	0.963	0.037
J44 Other chronic obstructive pulmonary disease	0.963	0.037
J43.9 Emphysema, unspecified	0.963	0.037
E70-E90 Metabolic disorders	0.959	0.041
R50-R69 General symptoms and signs	0.956	0.044
B35-B49 Mycoses	0.955	0.045
K50-K52 Noninfective enteritis and colitis	0.940	0.060
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.940	0.060
J84 Other interstitial pulmonary diseases	0.939	0.061
K90-K93 Other diseases of the digestive system	0.937	0.063
T66-T78 Other and unspecified effects of external causes	0.932	0.068
R55 Syncope and collapse	0.932	0.068
K50 Crohn's disease [regional enteritis]	0.928	0.072
F40-F48 Neurotic, stress-related and somatoform disorders	0.923	0.077
J47 Bronchiectasis	0.923	0.077
J84.1 Other interstitial pulmonary diseases with fibrosis	0.920	0.080
B37 Candidiasis	0.918	0.082
K70-K77 Diseases of liver	0.916	0.084
R52 Pain, not elsewhere classified	0.914	0.086
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.913	0.087
J95-J99 Other diseases of the respiratory system	0.908	0.092
H02.3 Blepharochalasis	0.908	0.092
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.907	0.093
D37-D48 Neoplasms of uncertain or unknown behaviour	0.906	0.094
Chapter XXI Factors influencing health status and contact with health services	0.904	0.096
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.900	0.100
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.896	0.104
H40-H42 Glaucoma	0.893	0.107
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.893	0.107
J90-J94 Other diseases of pleura	0.890	0.110
R91 Abnormal findings on diagnostic imaging of lung	0.887	0.113
J20-J22 Other acute lower respiratory infections	0.884	0.116
C15-C26 Malignant neoplasms of digestive organs	0.882	0.118
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.881	0.119
R52.1 Chronic intractable pain	0.878	0.122
K92 Other diseases of digestive system	0.877	0.123
R53 Malaise and fatigue	0.877	0.123
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.877	0.123
S80-S89 Injuries to the knee and lower leg	0.872	0.128
J13 Pneumonia due to Streptococcus pneumoniae	0.871	0.129
E87 Other disorders of fluid, electrolyte and acid-base balance	0.871	0.129
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.865	0.135
B95-B98 Bacterial, viral and other infectious agents	0.863	0.137
H02.5 Other disorders affecting eyelid function	0.861	0.139
S70-S79 Injuries to the hip and thigh	0.860	0.140
K50.1 Crohn's disease of large intestine	0.856	0.144
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.852	0.148
Z40-Z54 Persons encountering health services for specific procedures and health care	0.850	0.150
B37.0 Candidal stomatitis	0.849	0.151
E78.0 Pure hypercholesterolaemia	0.848	0.152
F30-F39 Mood [affective] disorders	0.844	0.156
R94 Abnormal results of function studies	0.844	0.156
T78 Adverse effects, not elsewhere classified	0.844	0.156
F41 Other anxiety disorders	0.842	0.158
J00-J06 Acute upper respiratory infections	0.840	0.160
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.839	0.161
K35-K38 Diseases of appendix	0.836	0.164
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.836	0.164
J93 Pneumothorax	0.833	0.167
H55-H59 Other disorders of eye and adnexa	0.831	0.169
C25 Malignant neoplasm of pancreas	0.830	0.170
F10 Mental and behavioural disorders due to use of alcohol	0.828	0.172
Chapter VI Diseases of the nervous system	0.825	0.175
E83 Disorders of mineral metabolism	0.824	0.176
Z51 Other medical care	0.824	0.176
E16 Other disorders of pancreatic internal secretion	0.822	0.178
J18.1 Lobar pneumonia, unspecified	0.822	0.178
H40 Glaucoma	0.821	0.179
T68 Hypothermia	0.821	0.179
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.821	0.179
H02.4 Ptosis of eyelid	0.820	0.180
D10-D36 Benign neoplasms	0.815	0.185
K50.9 Crohn's disease, unspecified	0.815	0.185
E11.3 With ophthalmic complications	0.812	0.188
K92.1 Melaena	0.810	0.190
K50.0 Crohn's disease of small intestine	0.809	0.191
B44 Aspergillosis	0.807	0.193
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.806	0.194
H02.9 Disorder of eyelid, unspecified	0.805	0.195
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.802	0.198
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.802	0.198
J22 Unspecified acute lower respiratory infection	0.801	0.199
E14 Unspecified diabetes mellitus	0.796	0.204
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.796	0.204
K55-K64 Other diseases of intestines	0.796	0.204
R50 Fever of unknown origin	0.794	0.206
R94.5 Abnormal results of liver function studies	0.794	0.206
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.794	0.206
H00 Hordeolum and chalazion	0.794	0.206
Z51.5 Palliative care	0.793	0.207
T78.4 Allergy, unspecified	0.790	0.210
J14 Pneumonia due to Haemophilus influenzae	0.786	0.214
Z50 Care involving use of rehabilitation procedures	0.786	0.214
Y52 Agents primarily affecting the cardiovascular system	0.784	0.216
V10-V19 Pedal cyclist injured in transport accident	0.782	0.218
E20-E35 Disorders of other endocrine glands	0.781	0.219
D27 Benign neoplasm of ovary	0.781	0.219
K70 Alcoholic liver disease	0.780	0.220
Chapter VIII Diseases of the ear and mastoid process	0.779	0.221
C78.0 Secondary malignant neoplasm of lung	0.778	0.222
F41.9 Anxiety disorder, unspecified	0.778	0.222
B37.3 Candidiasis of vulva and vagina	0.775	0.225
A30-A49 Other bacterial diseases	0.775	0.225
E10 Insulin-dependent diabetes mellitus	0.775	0.225
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.774	0.226
F43 Reaction to severe stress, and adjustment disorders	0.774	0.226
H46-H48 Disorders of optic nerve and visual pathways	0.773	0.227
K76 Other diseases of liver	0.772	0.228
H01 Other inflammation of eyelid	0.772	0.228
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.770	0.230
K62 Other diseases of anus and rectum	0.770	0.230
E16.2 Hypoglycaemia, unspecified	0.769	0.231
S81 Open wound of lower leg	0.769	0.231
D00-D09 In situ neoplasms	0.767	0.233
J98 Other respiratory disorders	0.767	0.233
M50-M54 Other dorsopathies	0.765	0.235
E87.2 Acidosis	0.764	0.236
K81 Cholecystitis	0.764	0.236
D45 Polycythaemia vera	0.763	0.237
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.762	0.238
K50.8 Other Crohn's disease	0.761	0.239
T51 Toxic effect of alcohol	0.758	0.242
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.758	0.242
H02.0 Entropion and trichiasis of eyelid	0.758	0.242
W00-W19 Falls	0.753	0.247
J11 Influenza, virus not identified	0.753	0.247
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.752	0.248
K75 Other inflammatory liver diseases	0.752	0.248
R57 Shock, not elsewhere classified	0.749	0.250
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.749	0.251
E83.5 Disorders of calcium metabolism	0.749	0.251
Z42 Follow-up care involving plastic surgery	0.748	0.252
S60-S69 Injuries to the wrist and hand	0.748	0.252
T15-T19 Effects of foreign body entering through natural orifice	0.747	0.253
J99 Respiratory disorders in diseases classified elsewhere	0.744	0.256
C25.0 Head of pancreas	0.743	0.257
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.743	0.257
M05-M14 Inflammatory polyarthropathies	0.742	0.257
J60-J70 Lung diseases due to external agents	0.741	0.258
M91-M94 Chondropathies	0.741	0.259
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.740	0.259
F10.1 Harmful use	0.740	0.259
E13 Other specified diabetes mellitus	0.737	0.263
F31 Bipolar affective disorder	0.735	0.265
Y41 Other systemic anti-infectives and antiparasitics	0.735	0.265
H53-H54 Visual disturbances and blindness	0.735	0.265
E88 Other metabolic disorders	0.732	0.268
F80-F89 Disorders of psychological development	0.732	0.268
A00-A09 Intestinal infectious diseases	0.731	0.269
E65-E68 Obesity and other hyperalimentation	0.730	0.270
H40.9 Glaucoma, unspecified	0.730	0.270
S72 Fracture of femur	0.730	0.270
C25.9 Pancreas, unspecified	0.727	0.273
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.726	0.274
K81.9 Cholecystitis, unspecified	0.725	0.275
J93.8 Other pneumothorax	0.725	0.275
K92.2 Gastro-intestinal haemorrhage, unspecified	0.724	0.276
H10-H13 Disorders of conjunctiva	0.723	0.276
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.723	0.277
C79 Secondary malignant neoplasm of other sites	0.722	0.278
J95 Postprocedural respiratory disorders, not elsewhere classified	0.721	0.279
C21 Malignant neoplasm of anus and anal canal	0.721	0.279
J81 Pulmonary oedema	0.720	0.279
C51-C58 Malignant neoplasms of female genital organs	0.720	0.280
T79-T79 Certain early complications of trauma	0.718	0.282
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.718	0.282
Y40 Systemic antibiotics	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Chapter XXII Codes for special purposes	0.717	0.283
E40-E46 Malnutrition	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.715	0.285
J41 Simple and mucopurulent chronic bronchitis	0.715	0.285
J46 Status asthmaticus	0.715	0.285
J17 Pneumonia in diseases classified elsewhere	0.715	0.285
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.715	0.285
J15 Bacterial pneumonia, not elsewhere classified	0.715	0.285
J12 Viral pneumonia, not elsewhere classified	0.715	0.285
J10 Influenza due to identified influenza virus	0.715	0.285
J09 Influenza due to certain identified influenza virus	0.715	0.285
K58 Irritable bowel syndrome	0.713	0.287
E11.8 With unspecified complications	0.713	0.287
E11.7 With multiple complications	0.713	0.287
E11.6 With other specified complications	0.713	0.287
E11.1 With ketoacidosis	0.713	0.287
E11.0 With coma	0.713	0.287
Z50.8 Care involving use of rehabilitation procedures	0.713	0.287
Y60-Y69 Misadventures to patients during surgical and medical care	0.713	0.287
C15 Malignant neoplasm of oesophagus	0.712	0.287
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.712	0.288
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.712	0.288
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.712	0.288
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.711	0.289
G90-G99 Other disorders of the nervous system	0.710	0.290
J18.8 Other pneumonia, organism unspecified	0.710	0.290
J18.2 Hypostatic pneumonia, unspecified	0.710	0.290
X40-X49 Accidental poisoning by and exposure to noxious substances	0.710	0.290
J44.9 Chronic obstructive pulmonary disease, unspecified	0.709	0.291
M54 Dorsalgia	0.708	0.292
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.708	0.292
F42 Obsessive-compulsive disorder	0.708	0.292
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.707	0.293
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.706	0.294
C40-C41 Malignant neoplasms of bone and articular cartilage	0.706	0.294
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.706	0.294
F99-F99 Unspecified mental disorder	0.706	0.294
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.706	0.294
F70-F79 Mental retardation	0.706	0.294
F60-F69 Disorders of adult personality and behaviour	0.706	0.294
K62.5 Haemorrhage of anus and rectum	0.706	0.294
T33-T35 Frostbite	0.705	0.294
T26-T28 Burns and corrosions confined to eye and internal organs	0.705	0.294
T20-T25 Burns and corrosions of external body surface, specified by site	0.705	0.294
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.705	0.294
T00-T07 Injuries involving multiple body regions	0.705	0.294
S10-S19 Injuries to the neck	0.705	0.294
C90 Multiple myeloma and malignant plasma cell neoplasms	0.705	0.295
B99-B99 Other infectious diseases	0.705	0.295
B90-B94 Sequelae of infectious and parasitic diseases	0.705	0.295
B85-B89 Pediculosis, acariasis and other infestations	0.705	0.295
B65-B83 Helminthiases	0.705	0.295
B50-B64 Protozoal diseases	0.705	0.295
B20-B24 Human immunodeficiency virus [HIV] disease	0.705	0.295
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.705	0.295
A80-A89 Viral infections of the central nervous system	0.705	0.295
A75-A79 Rickettsioses	0.705	0.295
A70-A74 Other diseases caused by chlamydiae	0.705	0.295
A65-A69 Other spirochaetal diseases	0.705	0.295
A50-A64 Infections with a predominantly sexual mode of transmission	0.705	0.295
A20-A28 Certain zoonotic bacterial diseases	0.705	0.295
A15-A19 Tuberculosis	0.705	0.295
V20-V29 Motorcycle rider injured in transport accident	0.705	0.295
S90-S99 Injuries to the ankle and foot	0.705	0.295
B37.8 Candidiasis of other sites	0.704	0.295
K76.0 Fatty (change of) liver, not elsewhere classified	0.704	0.296
H05 Disorders of orbit	0.704	0.296
H03 Disorders of eyelid in diseases classified elsewhere	0.704	0.296
J43.8 Other emphysema	0.700	0.299
J43.2 Centrilobular emphysema	0.700	0.299
J43.1 Panlobular emphysema	0.700	0.299
J43.0 MacLeod's syndrome	0.700	0.299
B44.1 Other pulmonary aspergillosis	0.701	0.299
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.700	0.300
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.700	0.300
R50.9 Fever, unspecified	0.697	0.303
T92 Sequelae of injuries of upper limb	0.696	0.304
S70 Superficial injury of hip and thigh	0.696	0.304
E11.2 With renal complications	0.695	0.305
B37.9 Candidiasis, unspecified	0.694	0.306
R25 Abnormal involuntary movements	0.693	0.307
J82 Pulmonary eosinophilia, not elsewhere classified	0.693	0.307
J80 Adult respiratory distress syndrome	0.693	0.307
H02.7 Other degenerative disorders of eyelid and periocular area	0.692	0.307
H02.6 Xanthelasma of eyelid	0.692	0.307
H02.2 Lagophthalmos	0.692	0.307
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.692	0.308
S82 Fracture of lower leg, including ankle	0.692	0.308
J93.9 Pneumothorax, unspecified	0.692	0.308
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.691	0.308
R95-R99 Ill-defined and unknown causes of mortality	0.691	0.308
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.691	0.309
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.691	0.309
Y35-Y36 Legal intervention and operations of war	0.691	0.309
Y10-Y34 Event of undetermined intent	0.691	0.309
Y00-Y09 Assault	0.691	0.309
X85-X99 Assault	0.691	0.309
X58-X59 Accidental exposure to other and unspecified factors	0.691	0.309
X50-X57 Overexertion, travel and privation	0.691	0.309
X30-X39 Exposure to forces of nature	0.691	0.309
X20-X29 Contact with venomous animals and plants	0.691	0.309
X10-X19 Contact with heat and hot substances	0.691	0.309
X00-X09 Exposure to smoke, fire and flames	0.691	0.309
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.691	0.309
W75-W84 Other accidental threats to breathing	0.691	0.309
W65-W74 Accidental drowning and submersion	0.691	0.309
W50-W64 Exposure to animate mechanical forces	0.691	0.309
V98-V99 Other and unspecified transport accidents	0.691	0.309
V95-V97 Air and space transport accidents	0.691	0.309
V90-V94 Water transport accidents	0.691	0.309
V80-V89 Other land transport accidents	0.691	0.309
V70-V79 Bus occupant injured in transport accident	0.691	0.309
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.691	0.309
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.691	0.309
V40-V49 Car occupant injured in transport accident	0.691	0.309
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.691	0.309
V01-V09 Pedestrian injured in transport accident	0.691	0.309
K62.8 Other specified diseases of anus and rectum	0.691	0.309
R52.9 Pain, unspecified	0.690	0.309
T51.0 Ethanol	0.690	0.310
R93 Abnormal findings on diagnostic imaging of other body structures	0.690	0.310
Y57 Other and unspecified drugs and medicaments	0.690	0.310
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.690	0.310
Z70-Z76 Persons encountering health services in other circumstances	0.689	0.311
E85 Amyloidosis	0.688	0.312
E84 Cystic fibrosis	0.688	0.312
E79 Disorders of purine and pyrimidine metabolism	0.688	0.312
E77 Disorders of glycoprotein metabolism	0.688	0.312
E76 Disorders of glycosaminoglycan metabolism	0.688	0.312
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.688	0.312
E74 Other disorders of carbohydrate metabolism	0.688	0.312
E73 Lactose intolerance	0.688	0.312
E72 Other disorders of amino-acid metabolism	0.688	0.312
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.688	0.312
E70 Disorders of aromatic amino-acid metabolism	0.688	0.312
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.688	0.312
Y52.3 Coronary vasodilators, not elsewhere classified	0.688	0.312
J93.1 Other spontaneous pneumothorax	0.686	0.314
R68 Other general symptoms and signs	0.685	0.315
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.685	0.315
R62 Lack of expected normal physiological development	0.685	0.315
R64 Cachexia	0.685	0.315
R58 Haemorrhage, not elsewhere classified	0.685	0.315
E87.6 Hypokalaemia	0.685	0.315
B15-B19 Viral hepatitis	0.685	0.315
B48 Other mycoses, not elsewhere classified	0.685	0.315
B47 Mycetoma	0.685	0.315
B46 Zygomycosis	0.685	0.315
B45 Cryptococcosis	0.685	0.315
B43 Chromomycosis and phaeomycotic abscess	0.685	0.315
B42 Sporotrichosis	0.685	0.315
B41 Paracoccidioidomycosis	0.685	0.315
B40 Blastomycosis	0.685	0.315
B39 Histoplasmosis	0.685	0.315
B38 Coccidioidomycosis	0.685	0.315
B36 Other superficial mycoses	0.685	0.315
B35 Dermatophytosis	0.685	0.315
B49 Unspecified mycosis	0.685	0.315
F17 Mental and behavioural disorders due to use of tobacco	0.684	0.316
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.683	0.317
S81.8 Open wound of other parts of lower leg	0.682	0.318
D37.7 Other digestive organs	0.680	0.320
M54.5 Low back pain	0.679	0.321
J84.9 Interstitial pulmonary disease, unspecified	0.678	0.322
D24 Benign neoplasm of breast	0.678	0.322
Z63 Other problems related to primary support group, including family circumstances	0.676	0.323
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.676	0.324
F10.3 Withdrawal state	0.676	0.324
F43.0 Acute stress reaction	0.676	0.324
J42 Unspecified chronic bronchitis	0.676	0.324
K74 Fibrosis and cirrhosis of liver	0.676	0.324
J06 Acute upper respiratory infections of multiple and unspecified sites	0.675	0.325
R90 Abnormal findings on diagnostic imaging of central nervous system	0.674	0.326
R92 Abnormal findings on diagnostic imaging of breast	0.674	0.326
E11.4 With neurological complications	0.674	0.326
J84.8 Other specified interstitial pulmonary diseases	0.673	0.326
J84.0 Alveolar and parietoalveolar conditions	0.673	0.326
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.673	0.327
R51 Headache	0.673	0.327
D16 Benign neoplasm of bone and articular cartilage	0.673	0.327
S20-S29 Injuries to the thorax	0.672	0.328
K93 Disorders of other digestive organs in diseases classified elsewhere	0.672	0.328
Y51 Drugs primarily affecting the autonomic nervous system	0.670	0.330
D33 Benign neoplasm of brain and other parts of central nervous system	0.669	0.331
H40.0 Glaucoma suspect	0.668	0.332
T75 Effects of other external causes	0.668	0.332
T74 Maltreatment syndromes	0.668	0.332
T73 Effects of other deprivation	0.668	0.332
T70 Effects of air pressure and water pressure	0.668	0.332
T69 Other effects of reduced temperature	0.668	0.332
T67 Effects of heat and light	0.668	0.332
T71 Asphyxiation	0.668	0.332
T66 Unspecified effects of radiation	0.668	0.332
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.668	0.332
J98.1 Pulmonary collapse	0.668	0.332
B97 Viral agents as the cause of diseases classified to other chapters	0.668	0.332
F10.4 Withdrawal state with delirium	0.668	0.332
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.666	0.334
R52.2 Other chronic pain	0.664	0.335
K38 Other diseases of appendix	0.664	0.335
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.664	0.336
W20-W49 Exposure to inanimate mechanical forces	0.664	0.336
H43-H45 Disorders of vitreous body and globe	0.664	0.336
Z42.1 Follow-up care involving plastic surgery of breast	0.664	0.336
R40 Somnolence, stupor and coma	0.664	0.336
C83 Diffuse non-Hodgkin's lymphoma	0.663	0.337
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.663	0.337
E87.5 Hyperkalaemia	0.663	0.337
F45 Somatoform disorders	0.662	0.338
K62.4 Stenosis of anus and rectum	0.662	0.338
F48 Other neurotic disorders	0.662	0.338
F44 Dissociative [conversion] disorders	0.662	0.338
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.662	0.338
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.661	0.339
Z51.4 Preparatory care for treatment, not elsewhere classified	0.661	0.339
J18.0 Bronchopneumonia, unspecified	0.661	0.339
C73 Malignant neoplasm of thyroid gland	0.660	0.339
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.660	0.340
B25-B34 Other viral diseases	0.660	0.340
K58.9 Irritable bowel syndrome without diarrhoea	0.660	0.340
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.658	0.341
K37 Unspecified appendicitis	0.658	0.342
B37.7 Candidal septicaemia	0.658	0.342
B37.6 Candidal endocarditis	0.658	0.342
B37.5 Candidal meningitis	0.658	0.342
B37.4 Candidiasis of other urogenital sites	0.658	0.342
B37.2 Candidiasis of skin and nail	0.658	0.342
B37.1 Pulmonary candidiasis	0.658	0.342
J92 Pleural plaque	0.657	0.343
K77 Liver disorders in diseases classified elsewhere	0.656	0.343
K73 Chronic hepatitis, not elsewhere classified	0.656	0.343
K71 Toxic liver disease	0.656	0.343
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.656	0.344
H02.1 Ectropion of eyelid	0.656	0.344
E78.2 Mixed hyperlipidaemia	0.656	0.344
R52.0 Acute pain	0.655	0.345
X60-X84 Intentional self-harm	0.654	0.345
Y59 Other and unspecified vaccines and biological substances	0.654	0.346
Y58 Bacterial vaccines	0.654	0.346
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.654	0.346
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.654	0.346
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.654	0.346
Y53 Agents primarily affecting the gastro-intestinal system	0.654	0.346
Y50 Central nervous system stimulants, not elsewhere classified	0.654	0.346
Y49 Psychotropic drugs, not elsewhere classified	0.654	0.346
Y48 Anaesthetics and therapeutic gases	0.654	0.346
Y47 Sedatives, hypnotics and antianxiety drugs	0.654	0.346
Y46 Antiepileptics and anti-Parkinsonism drugs	0.654	0.346
Y44 Agents primarily affecting blood constituents	0.654	0.346
C16 Malignant neoplasm of stomach	0.653	0.347
R47-R49 Symptoms and signs involving speech and voice	0.652	0.348
V18 Pedal cyclist injured in noncollision transport accident	0.652	0.348
F00-F09 Organic, including symptomatic, mental disorders	0.652	0.348
J96 Respiratory failure, not elsewhere classified	0.651	0.349
S00-S09 Injuries to the head	0.650	0.350
E87.7 Fluid overload	0.650	0.350
D46 Myelodysplastic syndromes	0.649	0.351
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.649	0.351
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.649	0.351
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.649	0.351
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.649	0.351
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.649	0.351
M80-M85 Disorders of bone density and structure	0.649	0.351
G00-G09 Inflammatory diseases of the central nervous system	0.649	0.351
E80 Disorders of porphyrin and bilirubin metabolism	0.649	0.351
Z51.3 Blood transfusion without reported diagnosis	0.647	0.353
Z45 Adjustment and management of implanted device	0.647	0.353
M05 Seropositive rheumatoid arthritis	0.647	0.353
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.646	0.354
D11 Benign neoplasm of major salivary glands	0.645	0.355
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.645	0.355
F18 Mental and behavioural disorders due to use of volatile solvents	0.645	0.355
F16 Mental and behavioural disorders due to use of hallucinogens	0.645	0.355
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.645	0.355
F14 Mental and behavioural disorders due to use of cocaine	0.645	0.355
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.645	0.355
F12 Mental and behavioural disorders due to use of cannabinoids	0.645	0.355
F11 Mental and behavioural disorders due to use of opioids	0.645	0.355
M40-M43 Deforming dorsopathies	0.644	0.356
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.644	0.356
E15 Nondiabetic hypoglycaemic coma	0.643	0.357
G40-G47 Episodic and paroxysmal disorders	0.643	0.357
Z57 Occupational exposure to risk-factors	0.641	0.359
H42 Glaucoma in diseases classified elsewhere	0.641	0.359
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.640	0.360
K35 Acute appendicitis	0.640	0.360
C76 Malignant neoplasm of other and ill-defined sites	0.640	0.360
R56 Convulsions, not elsewhere classified	0.640	0.360
C78.7 Secondary malignant neoplasm of liver	0.639	0.361
J94 Other pleural conditions	0.638	0.362
H55 Nystagmus and other irregular eye movements	0.638	0.362
D26 Other benign neoplasms of uterus	0.638	0.362
E87.1 Hypo-osmolality and hyponatraemia	0.637	0.362
T36-T50 Poisoning by drugs, medicaments and biological substances	0.637	0.363
K59 Other functional intestinal disorders	0.635	0.365
J04 Acute laryngitis and tracheitis	0.634	0.365
J21 Acute bronchiolitis	0.634	0.366
J20 Acute bronchitis	0.634	0.366
E11.5 With peripheral circulatory complications	0.633	0.367
C26 Malignant neoplasm of other and ill-defined digestive organs	0.633	0.367
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.633	0.367
C17 Malignant neoplasm of small intestine	0.633	0.367
C23 Malignant neoplasm of gallbladder	0.633	0.367
E14.9 Without complications	0.632	0.368
H57 Other disorders of eye and adnexa	0.632	0.368
G50-G59 Nerve, nerve root and plexus disorders	0.632	0.368
E78.9 Disorder of lipoprotein metabolism, unspecified	0.632	0.368
E78.8 Other disorders of lipoprotein metabolism	0.632	0.368
E78.6 Lipoprotein deficiency	0.632	0.368
E78.4 Other hyperlipidaemia	0.632	0.368
E78.3 Hyperchylomicronaemia	0.632	0.368

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations