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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16963349
log Bayes Factor = 0.00063379
Chromosome 16   position 84,338,234  (GRCh37) Explore rs16963349 on Ensembl!
Variant rs16963349 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
0.000 0.998 0.002
E11.9 Without complications
0.000 0.998 0.002
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.998 0.002
E11 Non-insulin-dependent diabetes mellitus
0.000 0.998 0.002
E70-E90 Metabolic disorders
0.000 0.998 0.002
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.998 0.002
E78.8 Other disorders of lipoprotein metabolism
0.000 0.998 0.002
E78.6 Lipoprotein deficiency
0.000 0.998 0.002
E78.5 Hyperlipidaemia, unspecified
0.000 0.998 0.002
E78.4 Other hyperlipidaemia
0.000 0.998 0.002
E78.3 Hyperchylomicronaemia
0.000 0.998 0.002
E78.2 Mixed hyperlipidaemia
0.000 0.998 0.002
E78.1 Pure hyperglyceridaemia
0.000 0.998 0.002
E10-E14 Diabetes mellitus
0.000 0.998 0.002
E11.8 With unspecified complications
0.000 0.998 0.001
E11.7 With multiple complications
0.000 0.998 0.001
E11.6 With other specified complications
0.000 0.998 0.001
E11.5 With peripheral circulatory complications
0.000 0.998 0.001
E11.4 With neurological complications
0.000 0.998 0.001
E11.3 With ophthalmic complications
0.000 0.998 0.001
E11.2 With renal complications
0.000 0.998 0.001
E11.1 With ketoacidosis
0.000 0.998 0.001
E11.0 With coma
0.000 0.998 0.001
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.998 0.001
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.998 0.001
E88 Other metabolic disorders
0.000 0.998 0.001
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.998 0.001
E85 Amyloidosis
0.000 0.998 0.001
E84 Cystic fibrosis
0.000 0.998 0.001
E83 Disorders of mineral metabolism
0.000 0.998 0.001
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.998 0.001
E79 Disorders of purine and pyrimidine metabolism
0.000 0.998 0.001
E77 Disorders of glycoprotein metabolism
0.000 0.998 0.001
E76 Disorders of glycosaminoglycan metabolism
0.000 0.998 0.001
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.998 0.001
E74 Other disorders of carbohydrate metabolism
0.000 0.998 0.001
E73 Lactose intolerance
0.000 0.998 0.001
E72 Other disorders of amino-acid metabolism
0.000 0.998 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.998 0.001
E70 Disorders of aromatic amino-acid metabolism
0.000 0.998 0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.998 0.001
E86 Volume depletion
0.000 0.998 0.001
E14 Unspecified diabetes mellitus
0.000 0.998 0.001
E13 Other specified diabetes mellitus
0.000 0.998 0.001
E12 Malnutrition-related diabetes mellitus
0.000 0.998 0.001
E10 Insulin-dependent diabetes mellitus
0.000 0.998 0.001
E65-E68 Obesity and other hyperalimentation
0.000 0.999 0.001
Z86.4 Personal history of psychoactive substance abuse
0.000 0.999 0.001
E00-E07 Disorders of thyroid gland
0.000 0.999 0.001
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.999 0.001
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.999 0.001
E70.3 Albinism
0.000 0.999 0.001
E70.2 Disorders of tyrosine metabolism
0.000 0.999 0.001
E70.1 Other hyperphenylalaninaemias
0.000 0.999 0.001
E70.0 Classical phenylketonuria
0.000 0.999 0.001
E71.3 Disorders of fatty-acid metabolism
0.000 0.999 0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.999 0.001
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.999 0.001
E71.0 Maple-syrup-urine disease
0.000 0.999 0.001
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.999 0.001
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.999 0.001
E72.5 Disorders of glycine metabolism
0.000 0.999 0.001
E72.4 Disorders of ornithine metabolism
0.000 0.999 0.001
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.999 0.001
E72.2 Disorders of urea cycle metabolism
0.000 0.999 0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.999 0.001
E72.0 Disorders of amino-acid transport
0.000 0.999 0.001
E73.9 Lactose intolerance, unspecified
0.000 0.999 0.001
E73.8 Other lactose intolerance
0.000 0.999 0.001
E73.1 Secondary lactase deficiency
0.000 0.999 0.001
E73.0 Congenital lactase deficiency
0.000 0.999 0.001
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.999 0.001
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.999 0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.999 0.001
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.999 0.001
E74.2 Disorders of galactose metabolism
0.000 0.999 0.001
E74.1 Disorders of fructose metabolism
0.000 0.999 0.001
E74.0 Glycogen storage disease
0.000 0.999 0.001
E75.6 Lipid storage disorder, unspecified
0.000 0.999 0.001
E75.5 Other lipid storage disorders
0.000 0.999 0.001
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.999 0.001
E75.3 Sphingolipidosis, unspecified
0.000 0.999 0.001
E75.2 Other sphingolipidosis
0.000 0.999 0.001
E75.1 Other gangliosidosis
0.000 0.999 0.001
E75.0 GM2 gangliosidosis
0.000 0.999 0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.999 0.001
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.999 0.001
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.999 0.001
E76.2 Other mucopolysaccharidoses
0.000 0.999 0.001
E76.1 Mucopolysaccharidosis, type II
0.000 0.999 0.001
E76.0 Mucopolysaccharidosis, type I
0.000 0.999 0.001
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.999 0.001
E77.8 Other disorders of glycoprotein metabolism
0.000 0.999 0.001
E77.1 Defects in glycoprotein degradation
0.000 0.999 0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.999 0.001
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.999 0.001
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.999 0.001
E79.1 Lesch-Nyhan syndrome
0.000 0.999 0.001
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.999 0.001
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.999 0.001
E80.6 Other disorders of bilirubin metabolism
0.000 0.999 0.001
E80.5 Crigler-Najjar syndrome
0.000 0.999 0.001
E80.4 Gilbert's syndrome
0.000 0.999 0.001
E80.3 Defects of catalase and peroxydase
0.000 0.999 0.001
E80.2 Other porphyria
0.000 0.999 0.001
E80.1 Porphyria cutanea tarda
0.000 0.999 0.001
E80.0 Hereditary erythropoietic porphyria
0.000 0.999 0.001
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.999 0.001
E83.8 Other disorders of mineral metabolism
0.000 0.999 0.001
E83.5 Disorders of calcium metabolism
0.000 0.999 0.001
E83.4 Disorders of magnesium metabolism
0.000 0.999 0.001
E83.3 Disorders of phosphorus metabolism
0.000 0.999 0.001
E83.2 Disorders of zinc metabolism
0.000 0.999 0.001
E83.1 Disorders of iron metabolism
0.000 0.999 0.001
E83.0 Disorders of copper metabolism
0.000 0.999 0.001
E84.9 Cystic fibrosis, unspecified
0.000 0.999 0.001
E84.8 Cystic fibrosis with other manifestations
0.000 0.999 0.001
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.999 0.001
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.999 0.001
E85.9 Amyloidosis, unspecified
0.000 0.999 0.001
E85.8 Other amyloidosis
0.000 0.999 0.001
E85.4 Organ-limited amyloidosis
0.000 0.999 0.001
E85.3 Secondary systemic amyloidosis
0.000 0.999 0.001
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.999 0.001
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.999 0.001
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.999 0.001
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.999 0.001
E87.7 Fluid overload
0.000 0.999 0.001
E87.6 Hypokalaemia
0.000 0.999 0.001
E87.5 Hyperkalaemia
0.000 0.999 0.001
E87.4 Mixed disorder of acid-base balance
0.000 0.999 0.001
E87.3 Alkalosis
0.000 0.999 0.001
E87.2 Acidosis
0.000 0.999 0.001
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.999 0.001
E87.0 Hyperosmolality and hypernatraemia
0.000 0.999 0.001
E88.9 Metabolic disorder, unspecified
0.000 0.999 0.001
E88.8 Other specified metabolic disorders
0.000 0.999 0.001
E88.3 Tumour lysis syndrome
0.000 0.999 0.001
E88.2 Lipomatosis, not elsewhere classified
0.000 0.999 0.001
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.999 0.001
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.999 0.001
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.999 0.001
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.999 0.001
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.999 0.001
E89.5 Postprocedural testicular hypofunction
0.000 0.999 0.001
E89.4 Postprocedural ovarian failure
0.000 0.999 0.001
E89.3 Postprocedural hypopituitarism
0.000 0.999 0.001
E89.2 Postprocedural hypoparathyroidism
0.000 0.999 0.001
E89.1 Postprocedural hypoinsulinaemia
0.000 0.999 0.001
E89.0 Postprocedural hypothyroidism
0.000 0.999 0.001
E66 Obesity
0.000 0.999 0.001
E50-E64 Other nutritional deficiencies
0.000 0.999 0.001
E40-E46 Malnutrition
0.000 0.999 0.001
E20-E35 Disorders of other endocrine glands
0.000 0.999 0.001
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.999 0.001
E10.9 Without complications
0.000 0.999 0.001
E10.8 With unspecified complications
0.000 0.999 0.001
E10.7 With multiple complications
0.000 0.999 0.001
E10.6 With other specified complications
0.000 0.999 0.001
E10.5 With peripheral circulatory complications
0.000 0.999 0.001
E10.4 With neurological complications
0.000 0.999 0.001
E10.3 With ophthalmic complications
0.000 0.999 0.001
E10.2 With renal complications
0.000 0.999 0.001
E10.1 With ketoacidosis
0.000 0.999 0.001
E10.0 With coma
0.000 0.999 0.001
E12.9 Without complications
0.000 0.999 0.001
E12.8 With unspecified complications
0.000 0.999 0.001
E12.7 With multiple complications
0.000 0.999 0.001
E12.6 With other specified complications
0.000 0.999 0.001
E12.5 With peripheral circulatory complications
0.000 0.999 0.001
E12.4 With neurological complications
0.000 0.999 0.001
E12.3 With ophthalmic complications
0.000 0.999 0.001
E12.2 With renal complications
0.000 0.999 0.001
E12.1 With ketoacidosis
0.000 0.999 0.001
E12.0 With coma
0.000 0.999 0.001
E13.9 Without complications
0.000 0.999 0.001
E13.8 With unspecified complications
0.000 0.999 0.001
E13.7 With multiple complications
0.000 0.999 0.001
E13.6 With other specified complications
0.000 0.999 0.001
E13.5 With peripheral circulatory complications
0.000 0.999 0.001
E13.4 With neurological complications
0.000 0.999 0.001
E13.3 With ophthalmic complications
0.000 0.999 0.001
E13.2 With renal complications
0.000 0.999 0.001
E13.1 With ketoacidosis
0.000 0.999 0.001
E13.0 With coma
0.000 0.999 0.001
E14.9 Without complications
0.000 0.999 0.001
E14.8 With unspecified complications
0.000 0.999 0.001
E14.7 With multiple complications
0.000 0.999 0.001
E14.6 With other specified complications
0.000 0.999 0.001
E14.5 With peripheral circulatory complications
0.000 0.999 0.001
E14.4 With neurological complications
0.000 0.999 0.001
E14.3 With ophthalmic complications
0.000 0.999 0.001
E14.2 Withrenal complications
0.000 0.999 0.001
E14.1 With ketoacidosis
0.000 0.999 0.001
E14.0 With coma
0.000 0.999 0.001
E66.9 Obesity, unspecified
0.000 0.999 0.001
E03 Other hypothyroidism
0.000 0.999 0.001
E67 Other hyperalimentation
0.000 0.999 0.001
E68 Sequelae of hyperalimentation
0.000 0.999 0.001
E65 Localised adiposity
0.000 0.999 0.001
Z86.7 Personal history of diseases of the circulatory system
0.000 0.999 0.001
E07 Other disorders of thyroid
0.000 0.999 0.001
E06 Thyroiditis
0.000 0.999 0.001
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.999 0.001
E04 Other non-toxic goitre
0.000 0.999 0.001
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.999 0.001
E00 Congenital iodine-deficiency syndrome
0.000 0.999 0.001
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.999 0.001
E66.8 Other obesity
0.000 0.999 0.001
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.999 0.001
E66.1 Drug-induced obesity
0.000 0.999 0.001
E66.0 Obesity due to excess calories
0.000 0.999 0.001
K29.7 Gastritis, unspecified
0.000 0.999 0.001
E16 Other disorders of pancreatic internal secretion
0.000 0.999 0.001
E15 Nondiabetic hypoglycaemic coma
0.000 0.999 0.001
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.999 0.001
E34 Other endocrine disorders
0.000 0.999 0.001
E32 Diseases of thymus
0.000 0.999 0.001
E31 Polyglandular dysfunction
0.000 0.999 0.001
E30 Disorders of puberty, not elsewhere classified
0.000 0.999 0.001
E29 Testicular dysfunction
0.000 0.999 0.001
E28 Ovarian dysfunction
0.000 0.999 0.001
E27 Other disorders of adrenal gland
0.000 0.999 0.001
E26 Hyperaldosteronism
0.000 0.999 0.001
E25 Adrenogenital disorders
0.000 0.999 0.001
E24 Cushing's syndrome
0.000 0.999 0.001
E23 Hypofunction and other disorders of pituitary gland
0.000 0.999 0.001
E22 Hyperfunction of pituitary gland
0.000 0.999 0.001
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.999 0.001
E20 Hypoparathyroidism
0.000 0.999 0.001
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.999 0.001
E46 Unspecified protein-energy malnutrition
0.000 0.999 0.001
E45 Retarded development following protein-energy malnutrition
0.000 0.999 0.001
E43 Unspecified severe protein-energy malnutrition
0.000 0.999 0.001
E42 Marasmic kwashiorkor
0.000 0.999 0.001
E41 Nutritional marasmus
0.000 0.999 0.001
E40 Kwashiorkor
0.000 0.999 0.001
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.999 0.001
E63 Other nutritional deficiencies
0.000 0.999 0.001
E61 Deficiency of other nutrient elements
0.000 0.999 0.001
E56 Other vitamin deficiencies
0.000 0.999 0.001
E55 Vitamin D deficiency
0.000 0.999 0.001
E53 Deficiency of other B group vitamins
0.000 0.999 0.001
E51 Thiamine deficiency
0.000 0.999 0.001
E50 Vitamin A deficiency
0.000 0.999 0.001
E60 Dietary zinc deficiency
0.000 0.999 0.001
E59 Dietary selenium deficiency
0.000 0.999 0.001
E58 Dietary calcium deficiency
0.000 0.999 0.001
E54 Ascorbic acid deficiency
0.000 0.999 0.001
E52 Niacin deficiency [pellagra]
0.000 0.999 0.001
E03.9 Hypothyroidism, unspecified
0.000 0.999 0.001
Z86 Personal history of certain other diseases
0.000 0.999 0.001
E03.8 Other specified hypothyroidism
0.000 0.999 0.001
E03.5 Myxoedema coma
0.000 0.999 0.001
E03.4 Atrophy of thyroid (acquired)
0.000 0.999 0.001
E03.3 Postinfectious hypothyroidism
0.000 0.999 0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.999 0.001
E03.1 Congenital hypothyroidism without goitre
0.000 0.999 0.001
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.999 0.001
E67.8 Other specified hyperalimentation
0.000 0.999 0.001
E67.3 Hypervitaminosis D
0.000 0.999 0.001
E67.2 Megavitamin-B6 syndrome
0.000 0.999 0.001
E67.1 Hypercarotenaemia
0.000 0.999 0.001
E67.0 Hypervitaminosis A
0.000 0.999 0.001
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.999 0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.999 0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.999 0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.999 0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.999 0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.999 0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.999 0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.999 0.001
E04.9 Non-toxic goitre, unspecified
0.000 0.999 0.001
E04.8 Other specified non-toxic goitre
0.000 0.999 0.001
E04.2 Non-toxic multinodular goitre
0.000 0.999 0.001
E04.1 Non-toxic single thyroid nodule
0.000 0.999 0.001
E04.0 Non-toxic diffuse goitre
0.000 0.999 0.001
E05.9 Thyrotoxicosis, unspecified
0.000 0.999 0.001
E05.8 Other thyrotoxicosis
0.000 0.999 0.001
E05.5 Thyroid crisis or storm
0.000 0.999 0.001
E05.4 Thyrotoxicosis factitia
0.000 0.999 0.001
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.999 0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.999 0.001
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.999 0.001
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.999 0.001
E06.9 Thyroiditis, unspecified
0.000 0.999 0.001
E06.5 Other chronic thyroiditis
0.000 0.999 0.001
E06.4 Drug-induced thyroiditis
0.000 0.999 0.001
E06.3 Autoimmune thyroiditis
0.000 0.999 0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.999 0.001
E06.1 Subacute thyroiditis
0.000 0.999 0.001
E06.0 Acute thyroiditis
0.000 0.999 0.001
E07.9 Disorder of thyroid, unspecified
0.000 0.999 0.001
E07.8 Other specified disorders of thyroid
0.000 0.999 0.001
E07.1 Dyshormogenetic goitre
0.000 0.999 0.001
E07.0 Hypersecretion of calcitonin
0.000 0.999 0.001
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.999 0.001
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.999 0.001
E16.4 Abnormal secretion of gastrin
0.000 0.999 0.001
E16.3 Increased secretion of glucagon
0.000 0.999 0.001
E16.2 Hypoglycaemia, unspecified
0.000 0.999 0.001
E16.1 Other hypoglycaemia
0.000 0.999 0.001
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.999 0.001
E20.9 Hypoparathyroidism, unspecified
0.000 0.999 0.001
E20.8 Other hypoparathyroidism
0.000 0.999 0.001
E20.1 Pseudohypoparathyroidism
0.000 0.999 0.001
E20.0 Idiopathic hypoparathyroidism
0.000 0.999 0.001
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.999 0.001
E21.4 Other specified disorders of parathyroid gland
0.000 0.999 0.001
E21.3 Hyperparathyroidism, unspecified
0.000 0.999 0.001
E21.2 Other hyperparathyroidism
0.000 0.999 0.001
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.999 0.001
E21.0 Primary hyperparathyroidism
0.000 0.999 0.001
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.999 0.001
E22.8 Other hyperfunction of pituitary gland
0.000 0.999 0.001
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.999 0.001
E22.1 Hyperprolactinaemia
0.000 0.999 0.001
E22.0 Acromegaly and pituitary gigantism
0.000 0.999 0.001
E23.7 Disorder of pituitary gland, unspecified
0.000 0.999 0.001
E23.6 Other disorders of pituitary gland
0.000 0.999 0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.999 0.001
E23.2 Diabetes insipidus
0.000 0.999 0.001
E23.1 Drug-induced hypopituitarism
0.000 0.999 0.001
E23.0 Hypopituitarism
0.000 0.999 0.001
E24.9 Cushing's syndrome, unspecified
0.000 0.999 0.001
E24.8 Other Cushing's syndrome
0.000 0.999 0.001
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.999 0.001
E24.3 Ectopic ACTH syndrome
0.000 0.999 0.001
E24.2 Drug-induced Cushing's syndrome
0.000 0.999 0.001
E24.1 Nelson's syndrome
0.000 0.999 0.001
E24.0 Pituitary-dependent Cushing's disease
0.000 0.999 0.001
E25.9 Adrenogenital disorder, unspecified
0.000 0.999 0.001
E25.8 Other adrenogenital disorders
0.000 0.999 0.001
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.999 0.001
E26.9 Hyperaldosteronism, unspecified
0.000 0.999 0.001
E26.8 Other hyperaldosteronism
0.000 0.999 0.001
E26.1 Secondary hyperaldosteronism
0.000 0.999 0.001
E26.0 Primary hyperaldosteronism
0.000 0.999 0.001
E27.9 Disorder of adrenal gland, unspecified
0.000 0.999 0.001
E27.8 Other specified disorders of adrenal gland
0.000 0.999 0.001
E27.5 Adrenomedullary hyperfunction
0.000 0.999 0.001
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.999 0.001
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.999 0.001
E27.2 Addisonian crisis
0.000 0.999 0.001
E27.1 Primary adrenocortical insufficiency
0.000 0.999 0.001
E27.0 Other adrenocortical overactivity
0.000 0.999 0.001
E28.9 Ovarian dysfunction, unspecified
0.000 0.999 0.001
E28.8 Other ovarian dysfunction
0.000 0.999 0.001
E28.3 Primary ovarian failure
0.000 0.999 0.001
E28.2 Polycystic ovarian syndrome
0.000 0.999 0.001
E28.1 Androgen excess
0.000 0.999 0.001
E28.0 Oestrogen excess
0.000 0.999 0.001
E29.9 Testicular dysfunction, unspecified
0.000 0.999 0.001
E29.8 Other testicular dysfunction
0.000 0.999 0.001
E29.1 Testicular hypofunction
0.000 0.999 0.001
E29.0 Testicular hyperfunction
0.000 0.999 0.001
E30.9 Disorder of puberty, unspecified
0.000 0.999 0.001
E30.8 Other disorders of puberty
0.000 0.999 0.001
E30.1 Precocious puberty
0.000 0.999 0.001
E30.0 Delayed puberty
0.000 0.999 0.001
E31.9 Polyglandular dysfunction, unspecified
0.000 0.999 0.001
E31.8 Other polyglandular dysfunction
0.000 0.999 0.001
E31.1 Polyglandular hyperfunction
0.000 0.999 0.001
E31.0 Autoimmune polyglandular failure
0.000 0.999 0.001
E32.9 Disease of thymus, unspecified
0.000 0.999 0.001
E32.8 Other diseases of thymus
0.000 0.999 0.001
E32.1 Abscess of thymus
0.000 0.999 0.001
E32.0 Persistent hyperplasia of thymus
0.000 0.999 0.001
E34.9 Endocrine disorder, unspecified
0.000 0.999 0.001
E34.8 Other specified endocrine disorders
0.000 0.999 0.001
E34.5 Androgen resistance syndrome
0.000 0.999 0.001
E34.4 Constitutional tall stature
0.000 0.999 0.001
E34.3 Short stature, not elsewhere classified
0.000 0.999 0.001
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.999 0.001
E34.1 Other hypersecretion of intestinal hormones
0.000 0.999 0.001
E34.0 Carcinoid syndrome
0.000 0.999 0.001
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.999 0.001
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.999 0.001
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.999 0.001
E44.1 Mild protein-energy malnutrition
0.000 0.999 0.001
E44.0 Moderate protein-energy malnutrition
0.000 0.999 0.001
E50.9 Vitamin A deficiency, unspecified
0.000 0.999 0.001
E50.8 Other manifestations of vitamin A deficiency
0.000 0.999 0.001
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.999 0.001
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.999 0.001
E50.5 Vitamin A deficiency with night blindness
0.000 0.999 0.001
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.999 0.001
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.999 0.001
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.999 0.001
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.999 0.001
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.999 0.001
E51.9 Thiamine deficiency, unspecified
0.000 0.999 0.001
E51.8 Other manifestations of thiamine deficiency
0.000 0.999 0.001
E51.2 Wernicke's encephalopathy
0.000 0.999 0.001
E51.1 Beriberi
0.000 0.999 0.001
E53.9 Vitamin B deficiency, unspecified
0.000 0.999 0.001
E53.8 Deficiency of other specified B group vitamins
0.000 0.999 0.001
E53.1 Pyridoxine deficiency
0.000 0.999 0.001
E53.0 Riboflavin deficiency
0.000 0.999 0.001
E55.9 Vitamin D deficiency, unspecified
0.000 0.999 0.001
E55.0 Rickets, active
0.000 0.999 0.001
E56.9 Vitamin deficiency, unspecified
0.000 0.999 0.001
E56.8 Deficiency of other vitamins
0.000 0.999 0.001
E56.1 Deficiency of vitamin K
0.000 0.999 0.001
E56.0 Deficiency of vitamin E
0.000 0.999 0.001
E61.9 Deficiency of nutrient element, unspecified
0.000 0.999 0.001
E61.8 Deficiency of other specified nutrient elements
0.000 0.999 0.001
E61.7 Deficiency of multiple nutrient elements
0.000 0.999 0.001
E61.6 Vanadium deficiency
0.000 0.999 0.001
E61.5 Molybdenum deficiency
0.000 0.999 0.001
E61.4 Chromium deficiency
0.000 0.999 0.001
E61.3 Manganese deficiency
0.000 0.999 0.001
E61.2 Magnesium deficiency
0.000 0.999 0.001
E61.1 Iron deficiency
0.000 0.999 0.001
E61.0 Copper deficiency
0.000 0.999 0.001
E63.9 Nutritional deficiency, unspecified
0.000 0.999 0.001
E63.8 Other specified nutritional deficiencies
0.000 0.999 0.001
E63.1 Imbalance of constituents of food intake
0.000 0.999 0.001
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.999 0.001
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.999 0.001
E64.8 Sequelae of other nutritional deficiencies
0.000 0.999 0.001
E64.3 Sequelae of rickets
0.000 0.999 0.001
E64.2 Sequelae of vitamin C deficiency
0.000 0.999 0.001
E64.1 Sequelae of vitamin A deficiency
0.000 0.999 0.001
E64.0 Sequelae of protein-energy malnutrition
0.000 0.999 0.001
Z86.6 Personal history of diseases of the nervous system and sense organs
0.000 0.999 0.001
Z86.5 Personal history of other mental and behavioural disorders
0.000 0.999 0.001
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.000 0.999 0.001
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.999 0.001
Z86.1 Personal history of infectious and parasitic diseases
0.000 0.999 0.001
Z86.0 Personal history of other neoplasms
0.000 0.999 0.001
N40 Hyperplasia of prostate
0.000 0.999 0.001
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.000 0.999 0.001
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.000 0.999 0.001
Z88.0 Personal history of allergy to penicillin
0.000 0.999 0.001
M16.1 Other primary coxarthrosis
0.001 0.999 0.000
K29 Gastritis and duodenitis
0.000 0.999 0.001
D64.9 Anaemia, unspecified
0.001 0.999 0.000
I20.9 Angina pectoris, unspecified
0.000 0.999 0.001
K21 Gastro-oesophageal reflux disease
0.000 0.999 0.001
K29.9 Gastroduodenitis, unspecified
0.000 0.999 0.001
K29.8 Duodenitis
0.000 0.999 0.001
K29.6 Other gastritis
0.000 0.999 0.001
K29.5 Chronic gastritis, unspecified
0.000 0.999 0.001
K29.4 Chronic atrophic gastritis
0.000 0.999 0.001
K29.3 Chronic superficial gastritis
0.000 0.999 0.001
K29.2 Alcoholic gastritis
0.000 0.999 0.001
K29.1 Other acute gastritis
0.000 0.999 0.001
K29.0 Acute haemorrhagic gastritis
0.000 0.999 0.001
M16.9 Coxarthrosis, unspecified
0.001 0.999 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.000 0.999 0.001
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.000 0.999 0.001
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.000 0.999 0.001
Z88.7 Personal history of allergy to serum and vaccine
0.000 0.999 0.001
Z88.6 Personal history of allergy to analgesic agent
0.000 0.999 0.001
Z88.5 Personal history of allergy to narcotic agent
0.000 0.999 0.001
Z88.4 Personal history of allergy to anaesthetic agent
0.000 0.999 0.001
Z88.3 Personal history of allergy to other anti-infective agents
0.000 0.999 0.001
Z88.2 Personal history of allergy to sulphonamides
0.000 0.999 0.001
Z88.1 Personal history of allergy to other antibiotic agents
0.000 0.999 0.001
M16.7 Other secondary coxarthrosis
0.001 0.999 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.001 0.999 0.000
M16.5 Other posttraumatic coxarthrosis
0.001 0.999 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.001 0.999 0.000
M16.3 Other dysplastic coxarthrosis
0.001 0.999 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.001 0.999 0.000
M16.0 Primary coxarthrosis, bilateral
0.001 0.999 0.000
M16 Coxarthrosis [arthrosis of hip]
0.001 0.999 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.999 0.001
N41.8 Other inflammatory diseases of prostate
0.000 0.999 0.001
N41.3 Prostatocystitis
0.000 0.999 0.001
N41.2 Abscess of prostate
0.000 0.999 0.001
N41.1 Chronic prostatitis
0.000 0.999 0.001
N41.0 Acute prostatitis
0.000 0.999 0.001
N42.9 Disorder of prostate, unspecified
0.000 0.999 0.001
N42.8 Other specified disorders of prostate
0.000 0.999 0.001
N42.3 Dysplasia of prostate
0.000 0.999 0.001
N42.2 Atrophy of prostate
0.000 0.999 0.001
N42.1 Congestion and haemorrhage of prostate
0.000 0.999 0.001
N42.0 Calculus of prostate
0.000 0.999 0.001
N43.4 Spermatocele
0.000 0.999 0.001
N43.3 Hydrocele, unspecified
0.000 0.999 0.001
N43.2 Other hydrocele
0.000 0.999 0.001
N43.1 Infected hydrocele
0.000 0.999 0.001
N43.0 Encysted hydrocele
0.000 0.999 0.001
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.999 0.001
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.999 0.001
N48.9 Disorder of penis, unspecified
0.000 0.999 0.001
N48.8 Other specified disorders of penis
0.000 0.999 0.001
N48.6 Balanitis xerotica obliterans
0.000 0.999 0.001
N48.5 Ulcer of penis
0.000 0.999 0.001
N48.4 Impotence of organic origin
0.000 0.999 0.001
N48.3 Priapism
0.000 0.999 0.001
N48.2 Other inflammatory disorders of penis
0.000 0.999 0.001
N48.1 Balanoposthitis
0.000 0.999 0.001
N48.0 Leukoplakia of penis
0.000 0.999 0.001
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.999 0.001
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.999 0.001
N49.2 Inflammatory disorders of scrotum
0.000 0.999 0.001
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.999 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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