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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16966085
log Bayes Factor = 5.66056
Chromosome 13   position 105,835,170  (GRCh37) Explore rs16966085 on Ensembl!
Variant rs16966085 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.999 0.001 0.000
O80-O84 Delivery
0.998 0.002 0.000
O80 Single spontaneous delivery
0.995 0.005 0.000
O80.0 Spontaneous vertex delivery
0.988 0.012 0.000
# Top node
0.987 0.013 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.987 0.013 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.980 0.020 0.000
S00-S09 Injuries to the head
0.979 0.021 0.000
O60-O75 Complications of labour and delivery
0.979 0.021 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.966 0.034 0.000
Chapter VI Diseases of the nervous system
0.961 0.039 0.000
G40-G47 Episodic and paroxysmal disorders
0.952 0.048 0.000
O70 Perineal laceration during delivery
0.950 0.050 0.000
Chapter V Mental and behavioural disorders
0.950 0.050 0.000
O20 Haemorrhage in early pregnancy
0.946 0.054 0.000
O00-O08 Pregnancy with abortive outcome
0.934 0.066 0.000
O70.1 Second degree perineal laceration during delivery
0.919 0.081 0.000
G43 Migraine
0.911 0.089 0.000
O80.9 Single spontaneous delivery, unspecified
0.908 0.092 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.908 0.092 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.906 0.094 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.905 0.095 0.000
S06 Intracranial injury
0.903 0.097 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.899 0.101 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.898 0.102 0.000
O42 Premature rupture of membranes
0.894 0.106 0.000
O03 Spontaneous abortion
0.891 0.109 0.000
O44 Placenta praevia
0.887 0.113 0.000
G47 Sleep disorders
0.887 0.113 0.000
G43.9 Migraine, unspecified
0.884 0.116 0.000
O47 False labour
0.875 0.125 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.865 0.135 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.863 0.137 0.000
S32 Fracture of lumbar spine and pelvis
0.862 0.138 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.855 0.145 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.854 0.146 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.853 0.147 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.848 0.152 0.000
O36 Maternal care for other known or suspected foetal problems
0.848 0.152 0.000
G47.9 Sleep disorder, unspecified
0.848 0.152 0.000
S01 Open wound of head
0.842 0.158 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.837 0.163 0.000
S05 Injury of eye and orbit
0.836 0.164 0.000
Chapter X Diseases of the respiratory system
0.834 0.166 0.000
O20.0 Threatened abortion
0.830 0.170 0.000
M80-M85 Disorders of bone density and structure
0.829 0.171 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.825 0.175 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.824 0.176 0.000
F43 Reaction to severe stress, and adjustment disorders
0.818 0.182 0.000
O03.9 Complete or unspecified, without complication
0.816 0.184 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.815 0.185 0.000
Chapter XXI Factors influencing health status and contact with health services
0.811 0.189 0.000
S00 Superficial injury of head
0.811 0.189 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.810 0.190 0.000
J30-J39 Other diseases of upper respiratory tract
0.809 0.191 0.000
O44.1 Placenta praevia with haemorrhage
0.808 0.192 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.805 0.195 0.000
T39.1 4-Aminophenol derivatives
0.805 0.195 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.803 0.197 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.801 0.199 0.000
O82 Single delivery by Caesarean section
0.800 0.200 0.000
F30-F39 Mood [affective] disorders
0.800 0.200 0.000
S02 Fracture of skull and facial bones
0.799 0.201 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.798 0.202 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.798 0.202 0.000
O70.0 First degree perineal laceration during delivery
0.797 0.203 0.000
G90-G99 Other disorders of the nervous system
0.797 0.203 0.000
O42.9 Premature rupture of membranes, unspecified
0.796 0.204 0.000
O32.1 Maternal care for breech presentation
0.795 0.205 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.789 0.211 0.000
O03.4 Incomplete, without complication
0.788 0.212 0.000
O81 Single delivery by forceps and vacuum extractor
0.786 0.213 0.000
O30 Multiple gestation
0.785 0.215 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.783 0.217 0.000
O23 Infections of genito-urinary tract in pregnancy
0.781 0.219 0.000
T39.0 Salicylates
0.780 0.220 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.777 0.223 0.000
O36.8 Maternal care for other specified foetal problems
0.776 0.224 0.000
M84 Disorders of continuity of bone
0.775 0.225 0.000
S06.5 Traumatic subdural haemorrhage
0.774 0.226 0.000
S10-S19 Injuries to the neck
0.771 0.229 0.000
S09 Other and unspecified injuries of head
0.769 0.231 0.000
E50-E64 Other nutritional deficiencies
0.767 0.233 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.766 0.234 0.000
Chapter XXII Codes for special purposes
0.760 0.240 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.760 0.240 0.000
M65-M68 Disorders of synovium and tendon
0.757 0.243 0.000
G70-G73 Diseases of myoneural junction and muscle
0.757 0.243 0.000
T66-T78 Other and unspecified effects of external causes
0.756 0.244 0.000
O20.8 Other haemorrhage in early pregnancy
0.754 0.245 0.000
Z36 Antenatal screening
0.754 0.246 0.000
S32.5 Fracture of pubis
0.753 0.247 0.000
O62 Abnormalities of forces of labour
0.753 0.247 0.000
F45 Somatoform disorders
0.752 0.248 0.000
O02 Other abnormal products of conception
0.752 0.248 0.000
O46.9 Antepartum haemorrhage, unspecified
0.749 0.251 0.000
S06.2 Diffuse brain injury
0.749 0.251 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.746 0.254 0.000
M95.0 Acquired deformity of nose
0.745 0.255 0.000
O73 Retained placenta and membranes, without haemorrhage
0.745 0.255 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.741 0.259 0.000
S01.8 Open wound of other parts of head
0.741 0.259 0.000
M05-M14 Inflammatory polyarthropathies
0.737 0.263 0.000
S90-S99 Injuries to the ankle and foot
0.736 0.264 0.000
G41 Status epilepticus
0.735 0.265 0.000
S50-S59 Injuries to the elbow and forearm
0.734 0.266 0.000
S05.9 Injury of eye and orbit, part unspecified
0.734 0.266 0.000
S00.8 Superficial injury of other parts of head
0.732 0.268 0.000
S32.4 Fracture of acetabulum
0.729 0.271 0.000
O32.4 Maternal care for high head at term
0.729 0.271 0.000
G45.4 Transient global amnesia
0.728 0.272 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.726 0.274 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.726 0.274 0.000
O24 Diabetes mellitus in pregnancy
0.725 0.275 0.000
F41 Other anxiety disorders
0.725 0.275 0.000
Z37 Outcome of delivery
0.725 0.275 0.000
J40-J47 Chronic lower respiratory diseases
0.724 0.276 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.724 0.276 0.000
O40 Polyhydramnios
0.723 0.276 0.000
J38.3 Other diseases of vocal cords
0.723 0.276 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.722 0.278 0.000
J32 Chronic sinusitis
0.721 0.279 0.000
G20-G26 Extrapyramidal and movement disorders
0.721 0.279 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
O45 Premature separation of placenta [abruptio placentae]
0.716 0.284 0.000
O43 Placental disorders
0.716 0.284 0.000
O41 Other disorders of amniotic fluid and membranes
0.716 0.284 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.716 0.284 0.000
O33 Maternal care for known or suspected disproportion
0.716 0.284 0.000
O31 Complications specific to multiple gestation
0.716 0.284 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.716 0.284 0.000
O84 Multiple delivery
0.715 0.285 0.000
O83 Other assisted single delivery
0.715 0.285 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.714 0.285 0.000
O21 Excessive vomiting in pregnancy
0.714 0.286 0.000
O80.8 Other single spontaneous delivery
0.713 0.287 0.000
O80.1 Spontaneous breech delivery
0.713 0.287 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.711 0.289 0.000
F40 Phobic anxiety disorders
0.709 0.291 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.708 0.292 0.000
T33-T35 Frostbite
0.708 0.292 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.708 0.292 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.708 0.292 0.000
T00-T07 Injuries involving multiple body regions
0.708 0.292 0.000
E00-E07 Disorders of thyroid gland
0.704 0.296 0.000
F43.2 Adjustment disorders
0.703 0.297 0.000
O29 Complications of anaesthesia during pregnancy
0.703 0.297 0.000
O28 Abnormal findings on antenatal screening of mother
0.703 0.297 0.000
O22 Venous complications in pregnancy
0.703 0.297 0.000
O25 Malnutrition in pregnancy
0.703 0.297 0.000
O66 Other obstructed labour
0.702 0.297 0.000
S08 Traumatic amputation of part of head
0.702 0.298 0.000
S07 Crushing injury of head
0.702 0.298 0.000
S04 Injury of cranial nerves
0.702 0.298 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.702 0.298 0.000
O74 Complications of anaesthesia during labour and delivery
0.702 0.298 0.000
O71 Other obstetric trauma
0.702 0.298 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.702 0.298 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.702 0.298 0.000
O61 Failed induction of labour
0.702 0.298 0.000
O60 Preterm delivery
0.702 0.298 0.000
S01.0 Open wound of scalp
0.702 0.298 0.000
G44 Other headache syndromes
0.697 0.302 0.000
Z36.8 Other antenatal screening
0.696 0.304 0.000
E65-E68 Obesity and other hyperalimentation
0.694 0.306 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.693 0.307 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.692 0.307 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.692 0.307 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.692 0.307 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.692 0.307 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.692 0.307 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.692 0.307 0.000
T36 Poisoning by systemic antibiotics
0.692 0.307 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.692 0.308 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.689 0.311 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.688 0.312 0.000
S06.0 Concussion
0.688 0.312 0.000
S32.3 Fracture of ilium
0.688 0.312 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.687 0.313 0.000
M50-M54 Other dorsopathies
0.687 0.313 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.687 0.313 0.000
G30-G32 Other degenerative diseases of the nervous system
0.686 0.314 0.000
F80-F89 Disorders of psychological development
0.686 0.314 0.000
T79-T79 Certain early complications of trauma
0.685 0.315 0.000
F32 Depressive episode
0.684 0.316 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.683 0.317 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.683 0.317 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.683 0.317 0.000
F41.2 Mixed anxiety and depressive disorder
0.683 0.317 0.000
O70.9 Perineal laceration during delivery, unspecified
0.681 0.319 0.000
O70.3 Fourth degree perineal laceration during delivery
0.681 0.319 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.681 0.319 0.000
F70-F79 Mental retardation
0.681 0.319 0.000
M86-M90 Other osteopathies
0.679 0.321 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.679 0.321 0.000
O32.0 Maternal care for unstable lie
0.678 0.322 0.000
J38.7 Other diseases of larynx
0.678 0.322 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.677 0.323 0.000
S01.2 Open wound of nose
0.677 0.323 0.000
F60-F69 Disorders of adult personality and behaviour
0.676 0.324 0.000
Z34 Supervision of normal pregnancy
0.676 0.324 0.000
S32.50 Fracture of pubis (closed)
0.676 0.324 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.675 0.324 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.675 0.325 0.000
Chapter I Certain infectious and parasitic diseases
0.675 0.325 0.000
J40 Bronchitis, not specified as acute or chronic
0.675 0.325 0.000
S80-S89 Injuries to the knee and lower leg
0.675 0.325 0.000
M80 Osteoporosis with pathological fracture
0.674 0.326 0.000
S40-S49 Injuries to the shoulder and upper arm
0.672 0.328 0.000
Q00-Q07 Congenital malformations of the nervous system
0.671 0.329 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.670 0.330 0.000
O07 Failed attempted abortion
0.670 0.330 0.000
O06 Unspecified abortion
0.670 0.330 0.000
O05 Other abortion
0.670 0.330 0.000
O01 Hydatidiform mole
0.670 0.330 0.000
Z37.0 Single live birth
0.670 0.330 0.000
F43.1 Posttraumatic stress disorder
0.669 0.331 0.000
F99-F99 Unspecified mental disorder
0.669 0.331 0.000
E55 Vitamin D deficiency
0.668 0.332 0.000
E40-E46 Malnutrition
0.668 0.332 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.667 0.333 0.000
E10-E14 Diabetes mellitus
0.667 0.333 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.664 0.336 0.000
O47.0 False labour before 37 completed weeks of gestation
0.664 0.336 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.661 0.339 0.000
S32.0 Fracture of lumbar vertebra
0.661 0.339 0.000
T43.2 Other and unspecified antidepressants
0.660 0.340 0.000
S02.0 Fracture of vault of skull
0.658 0.342 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.658 0.342 0.000
Z39 Postpartum care and examination
0.657 0.343 0.000
Z63 Other problems related to primary support group, including family circumstances
0.656 0.344 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.655 0.345 0.000
S02.1 Fracture of base of skull
0.653 0.347 0.000
G43.8 Other migraine
0.653 0.347 0.000
G43.3 Complicated migraine
0.653 0.347 0.000
G43.2 Status migrainosus
0.653 0.347 0.000
G43.0 Migraine without aura [common migraine]
0.653 0.347 0.000
G90 Disorders of autonomic nervous system
0.653 0.347 0.000
F48 Other neurotic disorders
0.651 0.349 0.000
F44 Dissociative [conversion] disorders
0.651 0.349 0.000
F42 Obsessive-compulsive disorder
0.651 0.349 0.000
G45.3 Amaurosis fugax
0.650 0.350 0.000
Z32 Pregnancy examination and test
0.650 0.350 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.649 0.350 0.000
S37 Injury of urinary and pelvic organs
0.649 0.350 0.000
S36 Injury of intra-abdominal organs
0.649 0.350 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.649 0.350 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.649 0.350 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.649 0.350 0.000
S31 Open wound of abdomen, lower back and pelvis
0.649 0.350 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.649 0.351 0.000
O32.8 Maternal care for other malpresentation of foetus
0.649 0.351 0.000
O32.6 Maternal care for compound presentation
0.649 0.351 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.649 0.351 0.000
O32.3 Maternal care for face, brow and chin presentation
0.649 0.351 0.000
O32.2 Maternal care for transverse and oblique lie
0.649 0.351 0.000
S20-S29 Injuries to the thorax
0.649 0.351 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.649 0.351 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.648 0.352 0.000
S06.9 Intracranial injury, unspecified
0.647 0.353 0.000
S06.8 Other intracranial injuries
0.647 0.353 0.000
S06.7 Intracranial injury with prolonged coma
0.647 0.353 0.000
S06.4 Epidural haemorrhage
0.647 0.353 0.000
S06.3 Focal brain injury
0.647 0.353 0.000
S06.1 Traumatic cerebral oedema
0.647 0.353 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.647 0.353 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.646 0.354 0.000
M06 Other rheumatoid arthritis
0.646 0.354 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.645 0.355 0.000
M40-M43 Deforming dorsopathies
0.645 0.355 0.000
O26.9 Pregnancy-related condition, unspecified
0.645 0.355 0.000
S00.5 Superficial injury of lip and oral cavity
0.645 0.355 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.644 0.356 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.644 0.356 0.000
T39.4 Antirheumatics, not elsewhere classified
0.644 0.356 0.000
T39.2 Pyrazolone derivatives
0.644 0.356 0.000
O16 Unspecified maternal hypertension
0.644 0.356 0.000
M91-M94 Chondropathies
0.644 0.356 0.000
M60-M63 Disorders of muscles
0.644 0.356 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.643 0.356 0.000
M50 Cervical disk disorders
0.643 0.357 0.000
T92 Sequelae of injuries of upper limb
0.643 0.357 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.642 0.358 0.000
E61 Deficiency of other nutrient elements
0.642 0.358 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.641 0.359 0.000
M00-M03 Infectious arthropathies
0.641 0.359 0.000
O70.2 Third degree perineal laceration during delivery
0.640 0.359 0.000
F45.8 Other somatoform disorders
0.641 0.359 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.639 0.361 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.639 0.361 0.000
O03.7 Complete or unspecified, complicated by embolism
0.639 0.361 0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.639 0.361 0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.639 0.361 0.000
O03.3 Incomplete, with other and unspecified complications
0.639 0.361 0.000
O03.2 Incomplete, complicated by embolism
0.639 0.361 0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.639 0.361 0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.639 0.361 0.000
M67 Other disorders of synovium and tendon
0.639 0.361 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.638 0.362 0.000
O44.0 Placenta praevia specified as without haemorrhage
0.636 0.364 0.000
G47.8 Other sleep disorders
0.636 0.364 0.000
G47.4 Narcolepsy and cataplexy
0.636 0.364 0.000
G47.2 Disorders of the sleep-wake schedule
0.636 0.364 0.000
Q23 Congenital malformations of aortic and mitral valves
0.636 0.364 0.000
O81.4 Vacuum extractor delivery
0.635 0.365 0.000
O48 Prolonged pregnancy
0.635 0.365 0.000
F33 Recurrent depressive disorder
0.634 0.366 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.634 0.366 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.634 0.366 0.000
J60-J70 Lung diseases due to external agents
0.634 0.366 0.000
S32.40 Fracture of acetabulum (closed)
0.633 0.367 0.000
O82.1 Delivery by emergency Caesarean section
0.633 0.367 0.000
G43.1 Migraine with aura [classical migraine]
0.633 0.367 0.000
O34.1 Maternal care for tumour of corpus uteri
0.633 0.367 0.000
O30.0 Twin pregnancy
0.632 0.368 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.632 0.368 0.000
Q80-Q89 Other congenital malformations
0.632 0.368 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.632 0.368 0.000
J30 Vasomotor and allergic rhinitis
0.630 0.370 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.629 0.371 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.628 0.371 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.628 0.372 0.000
Z35 Supervision of high-risk pregnancy
0.628 0.372 0.000
M05 Seropositive rheumatoid arthritis
0.628 0.372 0.000
O26.8 Other specified pregnancy-related conditions
0.626 0.374 0.000
J47 Bronchiectasis
0.620 0.380 0.000
M66 Spontaneous rupture of synovium and tendon
0.619 0.381 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.619 0.381 0.000
O63 Long labour
0.618 0.382 0.000
S09.9 Unspecified injury of head
0.618 0.382 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.618 0.382 0.000
S32.2 Fracture of coccyx
0.618 0.382 0.000
S32.1 Fracture of sacrum
0.618 0.382 0.000
M85 Other disorders of bone density and structure
0.617 0.383 0.000
O00 Ectopic pregnancy
0.617 0.383 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.616 0.384 0.000
J32.0 Chronic maxillary sinusitis
0.616 0.384 0.000
J38.1 Polyp of vocal cord and larynx
0.616 0.384 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.615 0.385 0.000
F43.0 Acute stress reaction
0.613 0.387 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.613 0.387 0.000
J36 Peritonsillar abscess
0.612 0.387 0.000
O36.5 Maternal care for poor foetal growth
0.612 0.388 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.612 0.388 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.612 0.388 0.000
G45.0 Vertebro-basilar artery syndrome
0.612 0.388 0.000
M84.0 Malunion of fracture
0.612 0.388 0.000
O46.8 Other antepartum haemorrhage
0.612 0.388 0.000
O46.0 Antepartum haemorrhage with coagulation defect
0.612 0.388 0.000
G93 Other disorders of brain
0.610 0.390 0.000
O23.5 Infections of the genital tract in pregnancy
0.609 0.391 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.609 0.391 0.000
O82.0 Delivery by elective Caesarean section
0.609 0.391 0.000
O36.9 Maternal care for foetal problem, unspecified
0.609 0.391 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.608 0.392 0.000
Q50-Q56 Congenital malformations of genital organs
0.608 0.392 0.000
Q35-Q37 Cleft lip and cleft palate
0.608 0.392 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.608 0.392 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.608 0.392 0.000
T14 Injury of unspecified body region
0.608 0.392 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.608 0.392 0.000
O36.4 Maternal care for intra-uterine death
0.608 0.392 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.608 0.392 0.000
O36.2 Maternal care for hydrops foetalis
0.608 0.392 0.000
O36.1 Maternal care for other isoimmunisation
0.608 0.392 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.604 0.395 0.000
S01.7 Multiple open wounds of head
0.604 0.396 0.000
S01.4 Open wound of cheek and temporomandibular area
0.604 0.396 0.000
O02.1 Missed abortion
0.603 0.397 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.602 0.398 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.601 0.399 0.000
G70 Myasthenia gravis and other myoneural disorders
0.601 0.399 0.000
M99 Biomechanical lesions, not elsewhere classified
0.600 0.400 0.000
Z36.9 Antenatal screening, unspecified
0.600 0.400 0.000
S05.8 Other injuries of eye and orbit
0.599 0.400 0.000
S05.7 Avulsion of eye
0.599 0.400 0.000
S05.6 Penetrating wound of eyeball without foreign body
0.599 0.400 0.000
S05.5 Penetrating wound of eyeball with foreign body
0.599 0.400 0.000
S05.4 Penetrating wound of orbit with or without foreign body
0.599 0.400 0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.599 0.400 0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.599 0.400 0.000
S05.1 Contusion of eyeball and orbital tissues
0.599 0.400 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.599 0.400 0.000
E55.9 Vitamin D deficiency, unspecified
0.598 0.402 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.597 0.402 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.597 0.403 0.000
M07 Psoriatic and enteropathic arthropathies
0.596 0.404 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.595 0.405 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.595 0.405 0.000
M50.3 Other cervical disk degeneration
0.595 0.405 0.000
M83 Adult osteomalacia
0.594 0.406 0.000
M82 Osteoporosis in diseases classified elsewhere
0.594 0.406 0.000
T93 Sequelae of injuries of lower limb
0.593 0.407 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.592 0.408 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.592 0.408 0.000
O34.6 Maternal care for abnormality of vagina
0.592 0.408 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.592 0.408 0.000
O34.4 Maternal care for other abnormalities of cervix
0.592 0.408 0.000
O34.3 Maternal care for cervical incompetence
0.592 0.408 0.000
O34.0 Maternal care for congenital malformation of uterus
0.592 0.408 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.591 0.409 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.591 0.409 0.000
T43.9 Psychotropic drug, unspecified
0.590 0.409 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.590 0.409 0.000
T43.6 Psychostimulants with abuse potential
0.590 0.409 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.590 0.409 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.590 0.409 0.000
O62.2 Other uterine inertia
0.590 0.409 0.000
O75.0 Maternal distress during labour and delivery
0.590 0.409 0.000
S51 Open wound of forearm
0.590 0.410 0.000
S01.1 Open wound of eyelid and periocular area
0.589 0.411 0.000
F29 Unspecified nonorganic psychosis
0.589 0.411 0.000
O04 Medical abortion
0.588 0.412 0.000
Z33 Pregnant state, incidental
0.587 0.413 0.000
F43.9 Reaction to severe stress, unspecified
0.586 0.414 0.000
F43.8 Other reactions to severe stress
0.586 0.414 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.586 0.414 0.000
O15 Eclampsia
0.585 0.415 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.585 0.415 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.585 0.415 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.585 0.415 0.000
Z29 Need for other prophylactic measures
0.583 0.417 0.000
Q23.1 Congenital insufficiency of aortic valve
0.583 0.417 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.582 0.417 0.000
T68 Hypothermia
0.582 0.418 0.000
T90 Sequelae of injuries of head
0.582 0.418 0.000
S00.7 Multiple superficial injuries of head
0.581 0.418 0.000
S00.4 Superficial injury of ear
0.581 0.418 0.000
S00.3 Superficial injury of nose
0.581 0.418 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.581 0.418 0.000
Z31 Procreative management
0.580 0.419 0.000
J37 Chronic laryngitis and laryngotracheitis
0.580 0.420 0.000
S02.3 Fracture of orbital floor
0.580 0.420 0.000
M06.9 Rheumatoid arthritis, unspecified
0.580 0.420 0.000
F22 Persistent delusional disorders
0.579 0.421 0.000
J43 Emphysema
0.579 0.421 0.000
G41.9 Status epilepticus, unspecified
0.579 0.421 0.000
J35 Chronic diseases of tonsils and adenoids
0.578 0.422 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.577 0.423 0.000
S12 Fracture of neck
0.577 0.423 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.577 0.423 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.577 0.423 0.000
O26.5 Maternal hypotension syndrome
0.577 0.423 0.000
O26.4 Herpes gestationis
0.577 0.423 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.577 0.423 0.000
O26.2 Pregnancy care of habitual aborter
0.577 0.423 0.000
O26.1 Low weight gain in pregnancy
0.577 0.423 0.000
O26.0 Excessive weight gain in pregnancy
0.577 0.423 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.577 0.423 0.000
O73.0 Retained placenta, without haemorrhage
0.577 0.423 0.000
F41.1 Generalised anxiety disorder
0.576 0.424 0.000
J90-J94 Other diseases of pleura
0.576 0.424 0.000
O72 Postpartum haemorrhage
0.576 0.424 0.000
O47.9 False labour, unspecified
0.576 0.424 0.000
Z38 Liveborn infants according to place of birth
0.575 0.424 0.000
J39 Other diseases of upper respiratory tract
0.575 0.425 0.000
G96 Other disorders of central nervous system
0.575 0.425 0.000
T50.8 Diagnostic agents
0.574 0.426 0.000
T50.7 Analeptics and opioid receptor antagonists
0.574 0.426 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.574 0.426 0.000
T50.5 Appetite depressants
0.574 0.426 0.000
T50.4 Drugs affecting uric acid metabolism
0.574 0.426 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.574 0.426 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.574 0.426 0.000
T50.1 Loop [high-ceiling] diuretics
0.574 0.426 0.000
T50.0 Mineralocorticoids and their antagonists
0.574 0.426 0.000
O82.9 Delivery by Caesarean section, unspecified
0.574 0.426 0.000
O82.8 Other single delivery by Caesarean section
0.574 0.426 0.000
O82.2 Delivery by Caesarean hysterectomy
0.574 0.426 0.000
F38 Other mood [affective] disorders
0.574 0.426 0.000
F34 Persistent mood [affective] disorders
0.574 0.426 0.000
F30 Manic episode
0.574 0.426 0.000
F39 Unspecified mood [affective] disorder
0.574 0.426 0.000
E66 Obesity
0.574 0.426 0.000
E10 Insulin-dependent diabetes mellitus
0.574 0.426 0.000
S02.8 Fractures of other skull and facial bones
0.573 0.427 0.000
S02.7 Multiple fractures involving skull and facial bones
0.573 0.427 0.000
S02.5 Fracture of tooth
0.573 0.427 0.000
T98 Sequelae of other and unspecified effects of external causes
0.572 0.428 0.000
T95 Sequelae of burns, corrosions and frostbite
0.572 0.428 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.572 0.428 0.000
T91 Sequelae of injuries of neck and trunk
0.572 0.428 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.572 0.428 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.572 0.428 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.572 0.428 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.572 0.428 0.000
T47.7 Emetics
0.572 0.428 0.000
T47.6 Antidiarrhoeal drugs
0.572 0.428 0.000
T47.5 Digestants
0.572 0.428 0.000
T47.4 Other laxatives
0.572 0.428 0.000
T47.3 Saline and osmotic laxatives
0.572 0.428 0.000
T47.2 Stimulant laxatives
0.572 0.428 0.000
T47.0 Histamine H(2)-receptor antagonists
0.572 0.428 0.000
J32.9 Chronic sinusitis, unspecified
0.571 0.429 0.000
S01.5 Open wound of lip and oral cavity
0.571 0.429 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.571 0.429 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.571 0.429 0.000
G92 Toxic encephalopathy
0.571 0.429 0.000
Z60 Problems related to social environment
0.570 0.430 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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