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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16975050
log Bayes Factor = 1.76679
Chromosome 18   position 39,187,170  (GRCh37) Explore rs16975050 on Ensembl!
Variant rs16975050 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.981 0.019 0.000
# Top node
0.981 0.019 0.000
Chapter XIV Diseases of the genitourinary system
0.973 0.027 0.000
Chapter XI Diseases of the digestive system
0.972 0.028 0.000
K90-K93 Other diseases of the digestive system
0.970 0.030 0.000
K92 Other diseases of digestive system
0.967 0.033 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.962 0.038 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.961 0.039 0.000
K92.1 Melaena
0.958 0.042 0.000
Chapter I Certain infectious and parasitic diseases
0.941 0.059 0.000
Chapter VI Diseases of the nervous system
0.928 0.072 0.000
N60-N64 Disorders of breast
0.923 0.077 0.000
B95-B98 Bacterial, viral and other infectious agents
0.923 0.077 0.000
Chapter VII Diseases of the eye and adnexa
0.916 0.084 0.000
K92.0 Haematemesis
0.914 0.086 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.911 0.089 0.000
K35-K38 Diseases of appendix
0.906 0.094 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.901 0.099 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.897 0.103 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.894 0.106 0.000
N80 Endometriosis
0.892 0.108 0.000
N10-N16 Renal tubulo-interstitial diseases
0.890 0.110 0.000
K31 Other diseases of stomach and duodenum
0.879 0.121 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.874 0.126 0.000
K25 Gastric ulcer
0.865 0.135 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.859 0.141 0.000
Chapter XX External causes of morbidity and mortality
0.852 0.148 0.000
K26 Duodenal ulcer
0.844 0.156 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.841 0.159 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.840 0.160 0.000
N63 Unspecified lump in breast
0.838 0.162 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.837 0.163 0.000
K31.7 Polyp of stomach and duodenum
0.835 0.165 0.000
H25-H28 Disorders of lens
0.835 0.165 0.000
G40-G47 Episodic and paroxysmal disorders
0.835 0.165 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.834 0.166 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.831 0.169 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.828 0.172 0.000
N94.1 Dyspareunia
0.827 0.173 0.000
N94.6 Dysmenorrhoea, unspecified
0.825 0.175 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.823 0.177 0.000
K70-K77 Diseases of liver
0.823 0.177 0.000
S40-S49 Injuries to the shoulder and upper arm
0.820 0.180 0.000
N00-N08 Glomerular diseases
0.818 0.182 0.000
N13 Obstructive and reflux uropathy
0.817 0.183 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.812 0.188 0.000
N92 Excessive, frequent and irregular menstruation
0.809 0.191 0.000
S60-S69 Injuries to the wrist and hand
0.806 0.194 0.000
K35 Acute appendicitis
0.804 0.196 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.801 0.199 0.000
H25 Senile cataract
0.801 0.199 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.798 0.202 0.000
Chapter XXII Codes for special purposes
0.795 0.205 0.000
T66-T78 Other and unspecified effects of external causes
0.793 0.207 0.000
N60 Benign mammary dysplasia
0.793 0.207 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.791 0.209 0.000
N86 Erosion and ectropion of cervix uteri
0.785 0.215 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.784 0.216 0.000
N80.1 Endometriosis of ovary
0.782 0.218 0.000
N64 Other disorders of breast
0.781 0.219 0.000
H10-H13 Disorders of conjunctiva
0.780 0.220 0.000
T43.2 Other and unspecified antidepressants
0.779 0.221 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.770 0.230 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.767 0.233 0.000
K38 Other diseases of appendix
0.766 0.234 0.000
G90-G99 Other disorders of the nervous system
0.763 0.237 0.000
H25.0 Senile incipient cataract
0.763 0.237 0.000
N89 Other noninflammatory disorders of vagina
0.762 0.238 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.761 0.239 0.000
S00-S09 Injuries to the head
0.758 0.242 0.000
N25-N29 Other disorders of kidney and ureter
0.757 0.243 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.756 0.244 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.755 0.245 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.755 0.245 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.753 0.246 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.753 0.247 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.750 0.250 0.000
G30-G32 Other degenerative diseases of the nervous system
0.747 0.253 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.746 0.254 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.741 0.259 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.741 0.259 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.739 0.261 0.000
K91.4 Colostomy and enterostomy malfunction
0.737 0.263 0.000
N83.2 Other and unspecified ovarian cysts
0.735 0.265 0.000
N02 Recurrent and persistent haematuria
0.731 0.269 0.000
N80.3 Endometriosis of pelvic peritoneum
0.728 0.272 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.726 0.274 0.000
A30-A49 Other bacterial diseases
0.725 0.275 0.000
N85.1 Endometrial adenomatous hyperplasia
0.725 0.275 0.000
S90-S99 Injuries to the ankle and foot
0.723 0.277 0.000
S20-S29 Injuries to the thorax
0.721 0.279 0.000
H53-H54 Visual disturbances and blindness
0.720 0.280 0.000
W20-W49 Exposure to inanimate mechanical forces
0.720 0.280 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.718 0.282 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.717 0.283 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.717 0.283 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.712 0.288 0.000
N80.8 Other endometriosis
0.710 0.290 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.709 0.291 0.000
Chapter IX Diseases of the circulatory system
0.708 0.292 0.000
K31.5 Obstruction of duodenum
0.708 0.292 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.707 0.293 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.704 0.296 0.000
A80-A89 Viral infections of the central nervous system
0.704 0.296 0.000
T79-T79 Certain early complications of trauma
0.703 0.296 0.000
T33-T35 Frostbite
0.703 0.296 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.703 0.296 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.703 0.296 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.703 0.296 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.703 0.296 0.000
T00-T07 Injuries involving multiple body regions
0.703 0.296 0.000
S10-S19 Injuries to the neck
0.703 0.296 0.000
Chapter V Mental and behavioural disorders
0.703 0.297 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.703 0.297 0.000
K31.4 Gastric diverticulum
0.701 0.299 0.000
N85.2 Hypertrophy of uterus
0.699 0.301 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.696 0.303 0.000
S70-S79 Injuries to the hip and thigh
0.695 0.304 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.695 0.304 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.694 0.306 0.000
H25.1 Senile nuclear cataract
0.693 0.306 0.000
K92.9 Disease of digestive system, unspecified
0.693 0.307 0.000
K92.8 Other specified diseases of digestive system
0.693 0.307 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.691 0.309 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.689 0.310 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.689 0.310 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.689 0.310 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.689 0.310 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.689 0.310 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.689 0.310 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.689 0.310 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.689 0.310 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.689 0.310 0.000
T36 Poisoning by systemic antibiotics
0.689 0.310 0.000
N98 Complications associated with artificial fertilisation
0.689 0.311 0.000
N91 Absent, scanty and rare menstruation
0.689 0.311 0.000
N82 Fistulae involving female genital tract
0.689 0.311 0.000
N96 Habitual aborter
0.689 0.311 0.000
K37 Unspecified appendicitis
0.686 0.314 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.685 0.315 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.685 0.315 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.684 0.316 0.000
H11 Other disorders of conjunctiva
0.683 0.317 0.000
T42.4 Benzodiazepines
0.683 0.317 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.681 0.319 0.000
G47 Sleep disorders
0.680 0.320 0.000
N92.3 Ovulation bleeding
0.679 0.321 0.000
B15-B19 Viral hepatitis
0.677 0.323 0.000
N60.3 Fibrosclerosis of breast
0.677 0.323 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.676 0.324 0.000
Q60-Q64 Congenital malformations of the urinary system
0.676 0.324 0.000
B99-B99 Other infectious diseases
0.674 0.325 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.674 0.325 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.674 0.325 0.000
B65-B83 Helminthiases
0.674 0.325 0.000
B50-B64 Protozoal diseases
0.674 0.325 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.674 0.325 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.674 0.325 0.000
A75-A79 Rickettsioses
0.674 0.325 0.000
A70-A74 Other diseases caused by chlamydiae
0.674 0.325 0.000
A65-A69 Other spirochaetal diseases
0.674 0.325 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.674 0.325 0.000
A20-A28 Certain zoonotic bacterial diseases
0.674 0.325 0.000
A15-A19 Tuberculosis
0.674 0.325 0.000
N88 Other noninflammatory disorders of cervix uteri
0.674 0.326 0.000
K74 Fibrosis and cirrhosis of liver
0.674 0.326 0.000
K25.3 Acute without haemorrhage or perforation
0.673 0.327 0.000
S42 Fracture of shoulder and upper arm
0.673 0.327 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.671 0.329 0.000
K35.9 Acute appendicitis, unspecified
0.671 0.329 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.670 0.329 0.000
V20-V29 Motorcycle rider injured in transport accident
0.670 0.330 0.000
N83.0 Follicular cyst of ovary
0.669 0.330 0.000
N80.9 Endometriosis, unspecified
0.669 0.331 0.000
N13.3 Other and unspecified hydronephrosis
0.668 0.332 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.668 0.332 0.000
T18 Foreign body in alimentary tract
0.667 0.333 0.000
K38.8 Other specified diseases of appendix
0.665 0.335 0.000
G70-G73 Diseases of myoneural junction and muscle
0.665 0.335 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.665 0.335 0.000
N97 Female infertility
0.661 0.339 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.661 0.339 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.660 0.340 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.660 0.340 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.659 0.341 0.000
T78 Adverse effects, not elsewhere classified
0.659 0.341 0.000
H55-H59 Other disorders of eye and adnexa
0.656 0.343 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.656 0.343 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.655 0.345 0.000
H25.8 Other senile cataract
0.655 0.345 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.654 0.346 0.000
N02.8 Other
0.654 0.346 0.000
N94.5 Secondary dysmenorrhoea
0.653 0.347 0.000
N94.4 Primary dysmenorrhoea
0.653 0.347 0.000
N94.3 Premenstrual tension syndrome
0.653 0.347 0.000
N94.2 Vaginismus
0.653 0.347 0.000
N94.0 Mittelschmerz
0.653 0.347 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.652 0.348 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.651 0.349 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.651 0.349 0.000
K36 Other appendicitis
0.650 0.350 0.000
N64.8 Other specified disorders of breast
0.649 0.351 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.648 0.352 0.000
T88.4 Failed or difficult intubation
0.648 0.352 0.000
I05-I09 Chronic rheumatic heart diseases
0.647 0.352 0.000
N61 Inflammatory disorders of breast
0.646 0.353 0.000
T87 Complications peculiar to reattachment and amputation
0.646 0.354 0.000
T86 Failure and rejection of transplanted organs and tissues
0.646 0.354 0.000
B35-B49 Mycoses
0.646 0.354 0.000
K90 Intestinal malabsorption
0.645 0.354 0.000
K91.3 Postoperative intestinal obstruction
0.645 0.355 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.644 0.356 0.000
T43.9 Psychotropic drug, unspecified
0.643 0.357 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.643 0.357 0.000
T43.6 Psychostimulants with abuse potential
0.643 0.357 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.643 0.357 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.643 0.357 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.643 0.357 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.641 0.358 0.000
K28 Gastrojejunal ulcer
0.641 0.359 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.641 0.359 0.000
I60-I69 Cerebrovascular diseases
0.640 0.360 0.000
N80.6 Endometriosis in cutaneous scar
0.639 0.361 0.000
N80.5 Endometriosis of intestine
0.639 0.361 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.639 0.361 0.000
N80.2 Endometriosis of Fallopian tube
0.639 0.361 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.639 0.361 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.639 0.361 0.000
K31.8 Other specified diseases of stomach and duodenum
0.639 0.361 0.000
S50-S59 Injuries to the elbow and forearm
0.638 0.362 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.638 0.362 0.000
N15 Other renal tubulo-interstitial diseases
0.638 0.362 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.638 0.362 0.000
N11 Chronic tubulo-interstitial nephritis
0.638 0.362 0.000
N10 Acute tubulo-interstitial nephritis
0.638 0.362 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.637 0.363 0.000
X60-X84 Intentional self-harm
0.637 0.363 0.000
N60.0 Solitary cyst of breast
0.637 0.363 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.636 0.364 0.000
S60 Superficial injury of wrist and hand
0.635 0.365 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.635 0.365 0.000
N85.0 Endometrial glandular hyperplasia
0.635 0.365 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.635 0.365 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.633 0.367 0.000
N99-N99 Other disorders of the genitourinary system
0.633 0.367 0.000
S02 Fracture of skull and facial bones
0.632 0.368 0.000
K27 Peptic ulcer, site unspecified
0.630 0.370 0.000
Q50-Q56 Congenital malformations of genital organs
0.630 0.370 0.000
K31.6 Fistula of stomach and duodenum
0.630 0.370 0.000
K31.3 Pylorospasm, not elsewhere classified
0.630 0.370 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.630 0.370 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.630 0.370 0.000
K31.0 Acute dilatation of stomach
0.630 0.370 0.000
G43 Migraine
0.628 0.372 0.000
K26.3 Acute without haemorrhage or perforation
0.627 0.372 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.626 0.374 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.626 0.374 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.626 0.374 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.625 0.375 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.625 0.375 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.625 0.375 0.000
K25.7 Chronic without haemorrhage or perforation
0.622 0.378 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.622 0.378 0.000
T93 Sequelae of injuries of lower limb
0.622 0.378 0.000
K76 Other diseases of liver
0.620 0.380 0.000
B25-B34 Other viral diseases
0.620 0.380 0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.620 0.380 0.000
K25.5 Chronic or unspecified with perforation
0.620 0.380 0.000
K25.4 Chronic or unspecified with haemorrhage
0.620 0.380 0.000
K25.2 Acute with both haemorrhage and perforation
0.620 0.380 0.000
K25.1 Acute with perforation
0.620 0.380 0.000
K25.0 Acute with haemorrhage
0.620 0.380 0.000
H18 Other disorders of cornea
0.620 0.380 0.000
K75 Other inflammatory liver diseases
0.619 0.380 0.000
N84 Polyp of female genital tract
0.619 0.381 0.000
H21 Other disorders of iris and ciliary body
0.619 0.381 0.000
K26.7 Chronic without haemorrhage or perforation
0.618 0.382 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.617 0.383 0.000
N80.0 Endometriosis of uterus
0.617 0.383 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.617 0.383 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.616 0.384 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.616 0.384 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.616 0.384 0.000
N85.4 Malposition of uterus
0.616 0.384 0.000
G47.9 Sleep disorder, unspecified
0.616 0.384 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.613 0.387 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.612 0.387 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.611 0.389 0.000
Y35-Y36 Legal intervention and operations of war
0.611 0.389 0.000
Y10-Y34 Event of undetermined intent
0.611 0.389 0.000
Y00-Y09 Assault
0.611 0.389 0.000
X85-X99 Assault
0.611 0.389 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.611 0.389 0.000
X50-X57 Overexertion, travel and privation
0.611 0.389 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.611 0.389 0.000
X30-X39 Exposure to forces of nature
0.611 0.389 0.000
X20-X29 Contact with venomous animals and plants
0.611 0.389 0.000
X10-X19 Contact with heat and hot substances
0.611 0.389 0.000
X00-X09 Exposure to smoke, fire and flames
0.611 0.389 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.611 0.389 0.000
W75-W84 Other accidental threats to breathing
0.611 0.389 0.000
W65-W74 Accidental drowning and submersion
0.611 0.389 0.000
W50-W64 Exposure to animate mechanical forces
0.611 0.389 0.000
V98-V99 Other and unspecified transport accidents
0.611 0.389 0.000
V95-V97 Air and space transport accidents
0.611 0.389 0.000
V90-V94 Water transport accidents
0.611 0.389 0.000
V80-V89 Other land transport accidents
0.611 0.389 0.000
V70-V79 Bus occupant injured in transport accident
0.611 0.389 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.611 0.389 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.611 0.389 0.000
V40-V49 Car occupant injured in transport accident
0.611 0.389 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.611 0.389 0.000
V01-V09 Pedestrian injured in transport accident
0.611 0.389 0.000
K65-K67 Diseases of peritoneum
0.610 0.390 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.608 0.392 0.000
G81 Hemiplegia
0.607 0.393 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.605 0.395 0.000
K26.5 Chronic or unspecified with perforation
0.605 0.395 0.000
K26.4 Chronic or unspecified with haemorrhage
0.605 0.395 0.000
K26.2 Acute with both haemorrhage and perforation
0.605 0.395 0.000
K26.1 Acute with perforation
0.605 0.395 0.000
K26.0 Acute with haemorrhage
0.605 0.395 0.000
K72 Hepatic failure, not elsewhere classified
0.605 0.395 0.000
S68 Traumatic amputation of wrist and hand
0.604 0.395 0.000
V10-V19 Pedal cyclist injured in transport accident
0.603 0.396 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.603 0.397 0.000
K91.5 Postcholecystectomy syndrome
0.603 0.397 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.603 0.397 0.000
K91.1 Postgastric surgery syndromes
0.603 0.397 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.603 0.397 0.000
T51 Toxic effect of alcohol
0.603 0.397 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.603 0.397 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.602 0.398 0.000
N85.7 Haematometra
0.602 0.398 0.000
N85.6 Intra-uterine synechiae
0.602 0.398 0.000
N85.5 Inversion of uterus
0.602 0.398 0.000
N85.3 Subinvolution of uterus
0.602 0.398 0.000
T40.4 Other synthetic narcotics
0.601 0.399 0.000
B02 Zoster [herpes zoster]
0.601 0.399 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.598 0.401 0.000
H27 Other disorders of lens
0.598 0.401 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.598 0.402 0.000
G44 Other headache syndromes
0.598 0.402 0.000
G41 Status epilepticus
0.598 0.402 0.000
S80-S89 Injuries to the knee and lower leg
0.598 0.402 0.000
S00 Superficial injury of head
0.597 0.403 0.000
N64.5 Other signs and symptoms in breast
0.596 0.404 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.596 0.404 0.000
Q80-Q89 Other congenital malformations
0.596 0.404 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.596 0.404 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.596 0.404 0.000
Q35-Q37 Cleft lip and cleft palate
0.596 0.404 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.596 0.404 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.596 0.404 0.000
Q00-Q07 Congenital malformations of the nervous system
0.596 0.404 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.594 0.406 0.000
N83.7 Haematoma of broad ligament
0.594 0.406 0.000
N83.6 Haematosalpinx
0.594 0.406 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.594 0.406 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.594 0.406 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.594 0.406 0.000
N89.5 Stricture and atresia of vagina
0.593 0.407 0.000
N93 Other abnormal uterine and vaginal bleeding
0.593 0.407 0.000
N92.6 Irregular menstruation, unspecified
0.592 0.408 0.000
T92 Sequelae of injuries of upper limb
0.591 0.409 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.590 0.409 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.590 0.409 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.590 0.409 0.000
T42.3 Barbiturates
0.590 0.409 0.000
T42.2 Succinimides and oxazolidinediones
0.590 0.409 0.000
T42.1 Iminostilbenes
0.590 0.409 0.000
T42.0 Hydantoin derivatives
0.590 0.409 0.000
N60.8 Other benign mammary dysplasias
0.590 0.410 0.000
W22 Striking against or struck by other objects
0.590 0.410 0.000
K77 Liver disorders in diseases classified elsewhere
0.590 0.410 0.000
K73 Chronic hepatitis, not elsewhere classified
0.590 0.410 0.000
K71 Toxic liver disease
0.590 0.410 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.588 0.412 0.000
S48 Traumatic amputation of shoulder and upper arm
0.588 0.412 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.588 0.412 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.588 0.412 0.000
S44 Injury of nerves at shoulder and upper arm level
0.588 0.412 0.000
S41 Open wound of shoulder and upper arm
0.588 0.412 0.000
S40 Superficial injury of shoulder and upper arm
0.588 0.412 0.000
S47 Crushing injury of shoulder and upper arm
0.588 0.412 0.000
K50-K52 Noninfective enteritis and colitis
0.587 0.413 0.000
W00-W19 Falls
0.587 0.413 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.587 0.413 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.587 0.413 0.000
N06 Isolated proteinuria with specified morphological lesion
0.587 0.413 0.000
N05 Unspecified nephritic syndrome
0.587 0.413 0.000
N04 Nephrotic syndrome
0.587 0.413 0.000
N01 Rapidly progressive nephritic syndrome
0.587 0.413 0.000
N00 Acute nephritic syndrome
0.587 0.413 0.000
K70 Alcoholic liver disease
0.587 0.413 0.000
G62 Other polyneuropathies
0.586 0.414 0.000
G91 Hydrocephalus
0.586 0.414 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.586 0.414 0.000
N13.8 Other obstructive and reflux uropathy
0.586 0.414 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.586 0.414 0.000
N13.6 Pyonephrosis
0.586 0.414 0.000
N13.4 Hydroureter
0.586 0.414 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.586 0.414 0.000
H11.0 Pterygium
0.584 0.416 0.000
G45.4 Transient global amnesia
0.583 0.417 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.582 0.418 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.582 0.418 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.582 0.418 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.582 0.418 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.582 0.418 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.582 0.418 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.582 0.418 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.582 0.418 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.582 0.418 0.000
T44.0 Anticholinesterase agents
0.582 0.418 0.000
S63.5 Sprain and strain of wrist
0.580 0.420 0.000
N92.5 Other specified irregular menstruation
0.580 0.420 0.000
N92.2 Excessive menstruation at puberty
0.580 0.420 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.580 0.420 0.000
N87 Dysplasia of cervix uteri
0.579 0.421 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.579 0.421 0.000
G83 Other paralytic syndromes
0.578 0.421 0.000
I69 Sequelae of cerebrovascular disease
0.578 0.422 0.000
S69 Other and unspecified injuries of wrist and hand
0.578 0.422 0.000
S67 Crushing injury of wrist and hand
0.578 0.422 0.000
S65 Injury of blood vessels at wrist and hand level
0.578 0.422 0.000
G20-G26 Extrapyramidal and movement disorders
0.577 0.423 0.000
K35.3 Acute appendicitis with localized peritonitis
0.577 0.423 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.577 0.423 0.000
N83.1 Corpus luteum cyst
0.577 0.423 0.000
H30-H36 Disorders of choroid and retina
0.576 0.423 0.000
N64.1 Fat necrosis of breast
0.576 0.424 0.000
H43-H45 Disorders of vitreous body and globe
0.576 0.424 0.000
G95 Other diseases of spinal cord
0.576 0.424 0.000
S64 Injury of nerves at wrist and hand level
0.575 0.425 0.000
H25.2 Senile cataract, morgagnian type
0.574 0.425 0.000
G96 Other disorders of central nervous system
0.574 0.426 0.000
T18.1 Foreign body in oesophagus
0.572 0.427 0.000
T19 Foreign body in genito-urinary tract
0.572 0.428 0.000
T17 Foreign body in respiratory tract
0.572 0.428 0.000
T15 Foreign body on external eye
0.572 0.428 0.000
T16 Foreign body in ear
0.572 0.428 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.571 0.429 0.000
N75 Diseases of Bartholin's gland
0.569 0.431 0.000
T75 Effects of other external causes
0.569 0.431 0.000
T74 Maltreatment syndromes
0.569 0.431 0.000
T73 Effects of other deprivation
0.569 0.431 0.000
T70 Effects of air pressure and water pressure
0.569 0.431 0.000
T69 Other effects of reduced temperature
0.569 0.431 0.000
T67 Effects of heat and light
0.569 0.431 0.000
T71 Asphyxiation
0.569 0.431 0.000
T68 Hypothermia
0.569 0.431 0.000
T66 Unspecified effects of radiation
0.569 0.431 0.000
N60.9 Benign mammary dysplasia, unspecified
0.568 0.431 0.000
N60.4 Mammary duct ectasia
0.568 0.431 0.000
N60.2 Fibroadenosis of breast
0.568 0.431 0.000
N92.4 Excessive bleeding in the premenopausal period
0.568 0.432 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.567 0.433 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.567 0.433 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.567 0.433 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.567 0.433 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.567 0.433 0.000
T83.2 Mechanical complication of graft of urinary organ
0.567 0.433 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.567 0.433 0.000
Y52 Agents primarily affecting the cardiovascular system
0.566 0.434 0.000
B07 Viral warts
0.565 0.435 0.000
I07 Rheumatic tricuspid valve diseases
0.564 0.436 0.000
Q61 Cystic kidney disease
0.564 0.436 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.563 0.437 0.000
N02.9 Unspecified
0.562 0.437 0.000
T98 Sequelae of other and unspecified effects of external causes
0.562 0.438 0.000
T95 Sequelae of burns, corrosions and frostbite
0.562 0.438 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.562 0.438 0.000
T91 Sequelae of injuries of neck and trunk
0.562 0.438 0.000
T90 Sequelae of injuries of head
0.562 0.438 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.562 0.438 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.562 0.438 0.000
W44 Foreign body entering into or through eye or natural orifice
0.561 0.439 0.000
K35.8 Acute appendicitis, other and unspecified
0.561 0.439 0.000
N64.9 Disorder of breast, unspecified
0.560 0.440 0.000
N64.4 Mastodynia
0.560 0.440 0.000
N64.3 Galactorrhoea not associated with childbirth
0.560 0.440 0.000
N64.2 Atrophy of breast
0.560 0.440 0.000
N64.0 Fissure and fistula of nipple
0.560 0.440 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.559 0.440 0.000
H10 Conjunctivitis
0.559 0.440 0.000
H50 Other strabismus
0.559 0.441 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.559 0.441 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.559 0.441 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.558 0.441 0.000
H04 Disorders of lachrymal system
0.558 0.442 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.557 0.443 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.552 0.448 0.000
H20 Iridocyclitis
0.552 0.448 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.552 0.448 0.000
H17 Corneal scars and opacities
0.552 0.448 0.000
H16 Keratitis
0.552 0.448 0.000
H15 Disorders of sclera
0.552 0.448 0.000
H54 Blindness and low vision
0.552 0.448 0.000
I08 Multiple valve diseases
0.552 0.448 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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