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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16976171
log Bayes Factor = 1.75054
Chromosome 18   position 40,059,621  (GRCh37) Explore rs16976171 on Ensembl!
Variant rs16976171 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.981 0.019 0.000
Chapter II Neoplasms
0.976 0.024 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.966 0.034 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.965 0.035 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.957 0.043 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.953 0.047 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.945 0.055 0.000
Chapter VI Diseases of the nervous system
0.923 0.077 0.000
K50-K52 Noninfective enteritis and colitis
0.922 0.078 0.000
Chapter XI Diseases of the digestive system
0.921 0.079 0.000
K52 Other non-infective gastro-enteritis and colitis
0.920 0.080 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.918 0.082 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.910 0.090 0.000
D50-D53 Nutritional anaemias
0.905 0.095 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.899 0.101 0.000
C78.2 Secondary malignant neoplasm of pleura
0.896 0.104 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.891 0.109 0.000
Chapter I Certain infectious and parasitic diseases
0.891 0.109 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.885 0.115 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.882 0.118 0.000
C79 Secondary malignant neoplasm of other sites
0.869 0.131 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.864 0.136 0.000
G90-G99 Other disorders of the nervous system
0.864 0.136 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.861 0.139 0.000
Chapter XXI Factors influencing health status and contact with health services
0.861 0.139 0.000
C43 Malignant melanoma of skin
0.856 0.144 0.000
D00-D09 In situ neoplasms
0.853 0.147 0.000
G35 Multiple sclerosis
0.853 0.147 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.847 0.153 0.000
Chapter XXII Codes for special purposes
0.844 0.156 0.000
Z37 Outcome of delivery
0.834 0.166 0.000
D50 Iron deficiency anaemia
0.829 0.171 0.000
Z37.0 Single live birth
0.825 0.175 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.824 0.176 0.000
L91 Hypertrophic disorders of skin
0.816 0.184 0.000
K51 Ulcerative colitis
0.812 0.188 0.000
Chapter V Mental and behavioural disorders
0.811 0.189 0.000
L89 Decubitus ulcer
0.809 0.191 0.000
C64-C68 Malignant neoplasms of urinary tract
0.808 0.192 0.000
L40-L45 Papulosquamous disorders
0.803 0.196 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.800 0.200 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.788 0.212 0.000
L50-L54 Urticaria and erythema
0.787 0.213 0.000
D70 Agranulocytosis
0.785 0.214 0.000
Z35 Supervision of high-risk pregnancy
0.783 0.217 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.782 0.218 0.000
K52.1 Toxic gastro-enteritis and colitis
0.780 0.220 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.779 0.221 0.000
D51 Vitamin B12 deficiency anaemia
0.778 0.222 0.000
C15-C26 Malignant neoplasms of digestive organs
0.777 0.223 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.771 0.229 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.764 0.236 0.000
K51.9 Ulcerative colitis, unspecified
0.761 0.239 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.758 0.242 0.000
L83 Acanthosis nigricans
0.754 0.246 0.000
B95-B98 Bacterial, viral and other infectious agents
0.752 0.248 0.000
C79.2 Secondary malignant neoplasm of skin
0.752 0.248 0.000
G95 Other diseases of spinal cord
0.750 0.250 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.746 0.254 0.000
C51-C58 Malignant neoplasms of female genital organs
0.744 0.255 0.000
D03 Melanoma in situ
0.738 0.261 0.000
C80 Malignant neoplasm without specification of site
0.737 0.263 0.000
C43.5 Malignant melanoma of trunk
0.736 0.264 0.000
L98.0 Pyogenic granuloma
0.736 0.264 0.000
F10.3 Withdrawal state
0.732 0.268 0.000
A15-A19 Tuberculosis
0.730 0.270 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.730 0.270 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.729 0.271 0.000
C60-C63 Malignant neoplasms of male genital organs
0.725 0.275 0.000
D60-D64 Aplastic and other anaemias
0.723 0.277 0.000
G93 Other disorders of brain
0.719 0.281 0.000
K35-K38 Diseases of appendix
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.285 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
D50.9 Iron deficiency anaemia, unspecified
0.713 0.287 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.709 0.291 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.708 0.292 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.705 0.295 0.000
D72 Other disorders of white blood cells
0.704 0.296 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.703 0.296 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.703 0.297 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.701 0.299 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.701 0.299 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.700 0.300 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.700 0.300 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.700 0.300 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.700 0.300 0.000
K50 Crohn's disease [regional enteritis]
0.698 0.301 0.000
D04 Carcinoma in situ of skin
0.696 0.304 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.695 0.305 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.694 0.306 0.000
L10-L14 Bullous disorders
0.693 0.307 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.692 0.308 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.692 0.308 0.000
D80-D89 Certain disorders involving the immune mechanism
0.691 0.309 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.690 0.310 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.688 0.312 0.000
L91.8 Other hypertrophic disorders of skin
0.688 0.312 0.000
L85 Other epidermal thickening
0.687 0.313 0.000
C44 Other malignant neoplasms of skin
0.687 0.313 0.000
Chapter XX External causes of morbidity and mortality
0.687 0.313 0.000
D55-D59 Haemolytic anaemias
0.686 0.314 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.683 0.317 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.683 0.317 0.000
L94 Other localised connective tissue disorders
0.683 0.317 0.000
L93 Lupus erythematosus
0.683 0.317 0.000
L87 Transepidermal elimination disorders
0.683 0.317 0.000
L88 Pyoderma gangrenosum
0.683 0.317 0.000
L86 Keratoderma in diseases classified elsewhere
0.683 0.317 0.000
L80 Vitiligo
0.683 0.317 0.000
L43 Lichen planus
0.682 0.318 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.682 0.318 0.000
M50-M54 Other dorsopathies
0.681 0.319 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.680 0.320 0.000
O36 Maternal care for other known or suspected foetal problems
0.679 0.321 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.678 0.322 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.678 0.322 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.678 0.322 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.677 0.323 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.676 0.324 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.676 0.324 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.673 0.327 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.672 0.328 0.000
L84 Corns and callosities
0.672 0.328 0.000
C18 Malignant neoplasm of colon
0.670 0.330 0.000
G37 Other demyelinating diseases of central nervous system
0.670 0.330 0.000
A80-A89 Viral infections of the central nervous system
0.669 0.331 0.000
C43.9 Malignant melanoma of skin, unspecified
0.668 0.332 0.000
L50 Urticaria
0.664 0.336 0.000
G70-G73 Diseases of myoneural junction and muscle
0.662 0.338 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.662 0.338 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.660 0.339 0.000
K52.3 Indeterminate colitis
0.659 0.340 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.659 0.340 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.659 0.340 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.659 0.340 0.000
M54 Dorsalgia
0.658 0.342 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.656 0.344 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.656 0.344 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.656 0.344 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.652 0.348 0.000
Z35.5 Supervision of elderly primigravida
0.652 0.348 0.000
B25-B34 Other viral diseases
0.651 0.349 0.000
K05 Gingivitis and periodontal diseases
0.651 0.349 0.000
L60-L75 Disorders of skin appendages
0.649 0.351 0.000
D53 Other nutritional anaemias
0.648 0.351 0.000
D52 Folate deficiency anaemia
0.648 0.351 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.647 0.353 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.647 0.353 0.000
A00-A09 Intestinal infectious diseases
0.644 0.356 0.000
L81 Other disorders of pigmentation
0.643 0.357 0.000
D75 Other diseases of blood and blood-forming organs
0.640 0.360 0.000
M80-M85 Disorders of bone density and structure
0.640 0.360 0.000
L89.1 Stage II decubitus ulcer
0.640 0.360 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.639 0.361 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.639 0.361 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.639 0.361 0.000
L98.5 Mucinosis of skin
0.639 0.361 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.639 0.361 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.639 0.361 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.639 0.361 0.000
L98.1 Factitial dermatitis
0.639 0.361 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.639 0.361 0.000
B99-B99 Other infectious diseases
0.639 0.361 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.639 0.361 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.639 0.361 0.000
B65-B83 Helminthiases
0.639 0.361 0.000
B50-B64 Protozoal diseases
0.639 0.361 0.000
B15-B19 Viral hepatitis
0.639 0.361 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.639 0.361 0.000
A75-A79 Rickettsioses
0.639 0.361 0.000
A70-A74 Other diseases caused by chlamydiae
0.639 0.361 0.000
A65-A69 Other spirochaetal diseases
0.639 0.361 0.000
A20-A28 Certain zoonotic bacterial diseases
0.639 0.361 0.000
L91.0 Keloid scar
0.638 0.362 0.000
C67 Malignant neoplasm of bladder
0.637 0.363 0.000
G36 Other acute disseminated demyelination
0.634 0.365 0.000
M54.5 Low back pain
0.633 0.367 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.633 0.367 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.632 0.367 0.000
Z39 Postpartum care and examination
0.632 0.367 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.632 0.367 0.000
G95.9 Disease of spinal cord, unspecified
0.631 0.369 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.631 0.369 0.000
Chapter VIII Diseases of the ear and mastoid process
0.630 0.369 0.000
G91 Hydrocephalus
0.630 0.370 0.000
Z33 Pregnant state, incidental
0.630 0.370 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.628 0.372 0.000
C16 Malignant neoplasm of stomach
0.628 0.372 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.627 0.373 0.000
B35-B49 Mycoses
0.624 0.376 0.000
Q00-Q07 Congenital malformations of the nervous system
0.623 0.377 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.623 0.377 0.000
C79.6 Secondary malignant neoplasm of ovary
0.623 0.377 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.623 0.377 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.623 0.377 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.623 0.377 0.000
Z37.2 Twins, both liveborn
0.623 0.377 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.620 0.380 0.000
D74 Methaemoglobinaemia
0.620 0.380 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.620 0.380 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.620 0.380 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.619 0.380 0.000
G96 Other disorders of central nervous system
0.619 0.380 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.619 0.380 0.000
G90 Disorders of autonomic nervous system
0.619 0.380 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.619 0.380 0.000
G92 Toxic encephalopathy
0.619 0.380 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.619 0.381 0.000
D06 Carcinoma in situ of cervix uteri
0.618 0.382 0.000
Q60-Q64 Congenital malformations of the urinary system
0.617 0.382 0.000
O85-O92 Complications predominantly related to the puerperium
0.617 0.383 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.617 0.383 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.617 0.383 0.000
D09 Carcinoma in situ of other and unspecified sites
0.616 0.384 0.000
K70-K77 Diseases of liver
0.615 0.384 0.000
G30-G32 Other degenerative diseases of the nervous system
0.615 0.385 0.000
O42 Premature rupture of membranes
0.615 0.385 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.615 0.385 0.000
C43.8 Overlapping malignant melanoma of skin
0.614 0.386 0.000
C43.4 Malignant melanoma of scalp and neck
0.614 0.386 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.614 0.386 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.614 0.386 0.000
C43.0 Malignant melanoma of lip
0.614 0.386 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.612 0.388 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.612 0.388 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.612 0.388 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.610 0.390 0.000
O30 Multiple gestation
0.608 0.392 0.000
O48 Prolonged pregnancy
0.607 0.393 0.000
Z38 Liveborn infants according to place of birth
0.607 0.393 0.000
Z32 Pregnancy examination and test
0.607 0.393 0.000
Z31 Procreative management
0.607 0.393 0.000
A30-A49 Other bacterial diseases
0.605 0.395 0.000
G95.2 Cord compression, unspecified
0.604 0.396 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.603 0.397 0.000
K12 Stomatitis and related lesions
0.603 0.397 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.603 0.397 0.000
C78.0 Secondary malignant neoplasm of lung
0.601 0.399 0.000
S20-S29 Injuries to the thorax
0.601 0.399 0.000
D64 Other anaemias
0.600 0.400 0.000
O60-O75 Complications of labour and delivery
0.600 0.400 0.000
D37.4 Colon
0.599 0.401 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.598 0.401 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.598 0.402 0.000
Z37.9 Outcome of delivery unspecified
0.598 0.402 0.000
Z37.7 Other multiple births, all stillborn
0.598 0.402 0.000
Z37.6 Other multiple births, some liveborn
0.598 0.402 0.000
Z37.5 Other multiple births, all liveborn
0.598 0.402 0.000
Z37.4 Twins, both stillborn
0.598 0.402 0.000
Z37.3 Twins, one liveborn and one stillborn
0.598 0.402 0.000
Z37.1 Single stillbirth
0.598 0.402 0.000
F10.1 Harmful use
0.597 0.403 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.596 0.403 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.596 0.404 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.596 0.404 0.000
L43.9 Lichen planus, unspecified
0.595 0.405 0.000
D50.1 Sideropenic dysphagia
0.594 0.406 0.000
K08 Other disorders of teeth and supporting structures
0.593 0.407 0.000
C44.3 Skin of other and unspecified parts of face
0.592 0.408 0.000
K36 Other appendicitis
0.591 0.409 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.591 0.409 0.000
Q80-Q89 Other congenital malformations
0.591 0.409 0.000
Q50-Q56 Congenital malformations of genital organs
0.591 0.409 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.591 0.409 0.000
Q35-Q37 Cleft lip and cleft palate
0.591 0.409 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.591 0.409 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.591 0.409 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.590 0.410 0.000
D72.8 Other specified disorders of white blood cells
0.590 0.410 0.000
U88 Agent resistant to multiple antibiotics
0.589 0.411 0.000
Z34 Supervision of normal pregnancy
0.589 0.411 0.000
K86 Other diseases of pancreas
0.589 0.411 0.000
G93.3 Postviral fatigue syndrome
0.587 0.413 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.587 0.413 0.000
M54.4 Lumbago with sciatica
0.586 0.414 0.000
S80-S89 Injuries to the knee and lower leg
0.586 0.414 0.000
L40 Psoriasis
0.585 0.415 0.000
L91.9 Hypertrophic disorder of skin, unspecified
0.585 0.415 0.000
F10.0 Acute intoxication
0.584 0.416 0.000
O36.5 Maternal care for poor foetal growth
0.583 0.417 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.583 0.417 0.000
K51.5 Mucosal proctocolitis
0.582 0.417 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.582 0.417 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.582 0.417 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.582 0.417 0.000
G20-G26 Extrapyramidal and movement disorders
0.582 0.418 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.582 0.418 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.582 0.418 0.000
L90 Atrophic disorders of skin
0.581 0.418 0.000
F99-F99 Unspecified mental disorder
0.581 0.419 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.581 0.419 0.000
F80-F89 Disorders of psychological development
0.581 0.419 0.000
F70-F79 Mental retardation
0.581 0.419 0.000
F60-F69 Disorders of adult personality and behaviour
0.581 0.419 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.581 0.419 0.000
C56 Malignant neoplasm of ovary
0.581 0.419 0.000
O80-O84 Delivery
0.581 0.419 0.000
O20 Haemorrhage in early pregnancy
0.581 0.419 0.000
L89.3 Stage IV decubitus ulcer
0.580 0.420 0.000
L89.2 Stage III decubitus ulcer
0.580 0.420 0.000
K82 Other diseases of gallbladder
0.580 0.420 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.579 0.421 0.000
C66 Malignant neoplasm of ureter
0.579 0.421 0.000
C65 Malignant neoplasm of renal pelvis
0.579 0.421 0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.579 0.421 0.000
Z22 Carrier of infectious disease
0.579 0.421 0.000
K51.4 Pseudopolyposis of colon
0.578 0.422 0.000
C18.0 Caecum
0.578 0.422 0.000
L50.9 Urticaria, unspecified
0.577 0.423 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.576 0.423 0.000
L44 Other papulosquamous disorders
0.576 0.424 0.000
L41 Parapsoriasis
0.576 0.424 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.576 0.424 0.000
L42 Pityriasis rosea
0.576 0.424 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.576 0.424 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.575 0.425 0.000
L20-L30 Dermatitis and eczema
0.574 0.426 0.000
M05-M14 Inflammatory polyarthropathies
0.574 0.426 0.000
D05 Carcinoma in situ of breast
0.573 0.427 0.000
M54.56 Low back pain (Lumbar region)
0.572 0.428 0.000
K90-K93 Other diseases of the digestive system
0.570 0.430 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.570 0.430 0.000
M86-M90 Other osteopathies
0.568 0.432 0.000
D04.5 Skin of trunk
0.568 0.432 0.000
D46 Myelodysplastic syndromes
0.568 0.432 0.000
D61 Other aplastic anaemias
0.568 0.432 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.566 0.434 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.565 0.435 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.565 0.435 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.565 0.435 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.565 0.435 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.565 0.435 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.565 0.435 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.565 0.435 0.000
L54 Erythema in diseases classified elsewhere
0.564 0.436 0.000
L51 Erythema multiforme
0.564 0.436 0.000
L52 Erythema nodosum
0.564 0.436 0.000
C44.2 Skin of ear and external auricular canal
0.564 0.436 0.000
C78.7 Secondary malignant neoplasm of liver
0.563 0.437 0.000
K02 Dental caries
0.563 0.437 0.000
M65-M68 Disorders of synovium and tendon
0.562 0.437 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.562 0.438 0.000
Z35.9 Supervision of high-risk pregnancy, unspecified
0.561 0.438 0.000
Z35.8 Supervision of other high-risk pregnancies
0.561 0.438 0.000
Z35.7 Supervision of high-risk pregnancy due to social problems
0.561 0.438 0.000
Z35.6 Supervision of very young primigravida
0.561 0.438 0.000
Z35.4 Supervision of pregnancy with grand multiparity
0.561 0.438 0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care
0.561 0.438 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.561 0.438 0.000
O45 Premature separation of placenta [abruptio placentae]
0.561 0.439 0.000
O44 Placenta praevia
0.561 0.439 0.000
O43 Placental disorders
0.561 0.439 0.000
O41 Other disorders of amniotic fluid and membranes
0.561 0.439 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.561 0.439 0.000
O33 Maternal care for known or suspected disproportion
0.561 0.439 0.000
O31 Complications specific to multiple gestation
0.561 0.439 0.000
O40 Polyhydramnios
0.561 0.439 0.000
C18.9 Colon, unspecified
0.560 0.440 0.000
K11 Diseases of salivary glands
0.559 0.441 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.558 0.441 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.558 0.441 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.558 0.441 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.558 0.441 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.558 0.441 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.558 0.441 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.558 0.441 0.000
F11 Mental and behavioural disorders due to use of opioids
0.558 0.441 0.000
C61 Malignant neoplasm of prostate
0.558 0.442 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.558 0.442 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.558 0.442 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.558 0.442 0.000
D51.2 Transcobalamin II deficiency
0.558 0.442 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.558 0.442 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.557 0.443 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.557 0.443 0.000
C21 Malignant neoplasm of anus and anal canal
0.557 0.443 0.000
C17 Malignant neoplasm of small intestine
0.557 0.443 0.000
C23 Malignant neoplasm of gallbladder
0.557 0.443 0.000
M54.59 Low back pain (Site unspecified)
0.557 0.443 0.000
G93.4 Encephalopathy, unspecified
0.555 0.444 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.555 0.445 0.000
S10-S19 Injuries to the neck
0.555 0.445 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.555 0.445 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.553 0.446 0.000
L53 Other erythematous conditions
0.553 0.447 0.000
F10.2 Dependence syndrome
0.553 0.447 0.000
K10 Other diseases of jaws
0.553 0.447 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.553 0.447 0.000
E10-E14 Diabetes mellitus
0.552 0.448 0.000
U51 Admission status on psychiatric patients
0.549 0.451 0.000
L05 Pilonidal cyst
0.549 0.451 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.548 0.452 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.548 0.452 0.000
A04 Other bacterial intestinal infections
0.548 0.452 0.000
K09 Cysts of oral region, not elsewhere classified
0.548 0.452 0.000
K07 Dentofacial anomalies [including malocclusion]
0.548 0.452 0.000
K03 Other diseases of hard tissues of teeth
0.548 0.452 0.000
K00 Disorders of tooth development and eruption
0.548 0.452 0.000
K51.8 Other ulcerative colitis
0.546 0.454 0.000
C54 Malignant neoplasm of corpus uteri
0.546 0.454 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.545 0.454 0.000
G40-G47 Episodic and paroxysmal disorders
0.545 0.455 0.000
O00-O08 Pregnancy with abortive outcome
0.544 0.456 0.000
K05.6 Periodontal disease, unspecified
0.544 0.456 0.000
F10.9 Unspecified mental and behavioural disorder
0.544 0.456 0.000
F10.8 Other mental and behavioural disorders
0.544 0.456 0.000
F10.7 Residual and late-onset psychotic disorder
0.544 0.456 0.000
F10.6 Amnesic syndrome
0.544 0.456 0.000
F10.5 Psychotic disorder
0.544 0.456 0.000
F10.4 Withdrawal state with delirium
0.544 0.456 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.539 0.461 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.538 0.462 0.000
G95.8 Other specified diseases of spinal cord
0.538 0.462 0.000
G95.1 Vascular myelopathies
0.538 0.462 0.000
G95.0 Syringomyelia and syringobulbia
0.538 0.462 0.000
S40-S49 Injuries to the shoulder and upper arm
0.537 0.462 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.537 0.462 0.000
O47 False labour
0.537 0.463 0.000
L85.8 Other specified epidermal thickening
0.536 0.464 0.000
Z60 Problems related to social environment
0.536 0.464 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.534 0.466 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.534 0.466 0.000
C51 Malignant neoplasm of vulva
0.534 0.466 0.000
C58 Malignant neoplasm of placenta
0.534 0.466 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.534 0.466 0.000
C52 Malignant neoplasm of vagina
0.534 0.466 0.000
C44.6 Skin of upper limb, including shoulder
0.533 0.467 0.000
Z36 Antenatal screening
0.533 0.467 0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation
0.532 0.468 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.532 0.468 0.000
Chapter XIV Diseases of the genitourinary system
0.530 0.470 0.000
C22.0 Liver cell carcinoma
0.530 0.470 0.000
O36.9 Maternal care for foetal problem, unspecified
0.530 0.470 0.000
D03.9 Melanoma in situ, unspecified
0.529 0.470 0.000
D03.8 Melanoma in situ of other sites
0.529 0.470 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.529 0.470 0.000
D03.5 Melanoma in situ of trunk
0.529 0.470 0.000
D03.4 Melanoma in situ of scalp and neck
0.529 0.470 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.529 0.470 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.529 0.470 0.000
D03.0 Melanoma in situ of lip
0.529 0.470 0.000
C45 Mesothelioma
0.529 0.471 0.000
D45 Polycythaemia vera
0.528 0.472 0.000
E20-E35 Disorders of other endocrine glands
0.528 0.472 0.000
E11 Non-insulin-dependent diabetes mellitus
0.527 0.473 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.527 0.473 0.000
M81 Osteoporosis without pathological fracture
0.527 0.473 0.000
K35 Acute appendicitis
0.526 0.473 0.000
V80-V89 Other land transport accidents
0.525 0.474 0.000
S90-S99 Injuries to the ankle and foot
0.525 0.475 0.000
D86 Sarcoidosis
0.525 0.475 0.000
D37.5 Rectum
0.525 0.475 0.000
K65-K67 Diseases of peritoneum
0.525 0.475 0.001
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.525 0.475 0.000
T79-T79 Certain early complications of trauma
0.523 0.476 0.000
A19 Miliary tuberculosis
0.523 0.477 0.000
A18 Tuberculosis of other organs
0.523 0.477 0.000
A17 Tuberculosis of nervous system
0.523 0.477 0.000
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed
0.523 0.477 0.000
M91-M94 Chondropathies
0.523 0.477 0.000
M60-M63 Disorders of muscles
0.523 0.477 0.000
M00-M03 Infectious arthropathies
0.523 0.477 0.000
T33-T35 Frostbite
0.523 0.477 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.523 0.477 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.523 0.477 0.000
T00-T07 Injuries involving multiple body regions
0.523 0.477 0.000
K05.1 Chronic gingivitis
0.523 0.477 0.000
C67.3 Anterior wall of bladder
0.523 0.477 0.000
D73 Diseases of spleen
0.522 0.477 0.000
K50.1 Crohn's disease of large intestine
0.522 0.477 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.522 0.478 0.000
D04.3 Skin of other and unspecified parts of face
0.522 0.478 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.522 0.478 0.000
S70-S79 Injuries to the hip and thigh
0.521 0.479 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.520 0.479 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.520 0.480 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.520 0.480 0.000
C60 Malignant neoplasm of penis
0.520 0.480 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.519 0.481 0.000
K51.2 Ulcerative (chronic) proctitis
0.518 0.481 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.518 0.482 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.518 0.482 0.000
G93.8 Other specified disorders of brain
0.518 0.482 0.000
C53 Malignant neoplasm of cervix uteri
0.517 0.483 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.517 0.483 0.000
U89 Agent resistant to other and unspecified antibiotics
0.517 0.483 0.000
C18.5 Splenic flexure
0.516 0.484 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.516 0.484 0.000
G93.9 Disorder of brain, unspecified
0.515 0.485 0.000
G93.7 Reye's syndrome
0.515 0.485 0.000
G93.6 Cerebral oedema
0.515 0.485 0.000
G93.5 Compression of brain
0.515 0.485 0.000
G93.2 Benign intracranial hypertension
0.515 0.485 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.515 0.485 0.000
G93.0 Cerebral cysts
0.515 0.485 0.000
Z29 Need for other prophylactic measures
0.515 0.485 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.515 0.485 0.000
K38 Other diseases of appendix
0.514 0.486 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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