TreeWAS – Variant ID: rs16989979

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.163	0.837	0.000
D50 Iron deficiency anaemia	0.030	0.970	0.000
M21.2 Flexion deformity	0.029	0.971	0.000
M21.27 Flexion deformity (Ankle and foot)	0.029	0.971	0.000
M21.24 Flexion deformity (Hand)	0.027	0.973	0.000
M21.26 Flexion deformity (Lower leg)	0.026	0.974	0.000
M21 Other acquired deformities of limbs	0.024	0.976	0.000
D50.1 Sideropenic dysphagia	0.022	0.978	0.000
M21.1 Varus deformity, not elsewhere classified	0.021	0.979	0.000
M21.29 Flexion deformity (Site unspecified)	0.021	0.979	0.000
M21.28 Flexion deformity (Other)	0.021	0.979	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.021	0.979	0.000
M21.23 Flexion deformity (Forearm)	0.021	0.979	0.000
M21.22 Flexion deformity (Upper arm)	0.021	0.979	0.000
M21.21 Flexion deformity (Shoulder region)	0.021	0.979	0.000
M21.20 Flexion deformity (Multiple sites)	0.021	0.979	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.021	0.979	0.000
M21.0 Valgus deformity, not elsewhere classified	0.020	0.979	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.020	0.980	0.000
D50-D53 Nutritional anaemias	0.020	0.980	0.000
M21.7 Unequal limb length (acquired)	0.019	0.981	0.000
M21.9 Acquired deformity of limb, unspecified	0.018	0.982	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.018	0.982	0.000
D53 Other nutritional anaemias	0.017	0.983	0.000
M21.8 Other specified acquired deformities of limbs	0.017	0.983	0.000
D51 Vitamin B12 deficiency anaemia	0.017	0.983	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.017	0.983	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.017	0.983	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.017	0.983	0.000
M21.4 Flat foot [pes planus] (acquired)	0.016	0.984	0.000
K11.5 Sialolithiasis	0.016	0.984	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.015	0.984	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.015	0.984	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.015	0.984	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.015	0.984	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.015	0.984	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.015	0.984	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.015	0.984	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.015	0.984	0.000
D53.9 Nutritional anaemia, unspecified	0.016	0.984	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.015	0.985	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.015	0.985	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.015	0.985	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.015	0.985	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.015	0.985	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.015	0.985	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.015	0.985	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.015	0.985	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.015	0.985	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.015	0.985	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.015	0.985	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.015	0.985	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.015	0.985	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.015	0.985	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.015	0.985	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.015	0.985	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.015	0.985	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.015	0.985	0.000
M21.6 Other acquired deformities of ankle and foot	0.015	0.985	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.014	0.986	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.013	0.986	0.000
M21.78 Unequal limb length (acquired)-Other	0.013	0.986	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.013	0.986	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.013	0.986	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.013	0.986	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.013	0.986	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.013	0.986	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.013	0.986	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.013	0.986	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.013	0.987	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.013	0.987	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.013	0.987	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.013	0.987	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.013	0.987	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.013	0.987	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.013	0.987	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.013	0.987	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.013	0.987	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.013	0.987	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.013	0.987	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.013	0.987	0.000
K11 Diseases of salivary glands	0.013	0.987	0.000
D53.8 Other specified nutritional anaemias	0.013	0.987	0.000
D53.2 Scorbutic anaemia	0.013	0.987	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.013	0.987	0.000
D53.0 Protein deficiency anaemia	0.013	0.987	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.013	0.987	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.013	0.987	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.013	0.987	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.013	0.987	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.013	0.987	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.013	0.987	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.013	0.987	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.013	0.987	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.013	0.987	0.000
D51.2 Transcobalamin II deficiency	0.013	0.987	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.013	0.987	0.000
S61.1 Open wound of finger(s) with damage to nail	0.013	0.987	0.000
M21.3 Wrist or foot drop (acquired)	0.012	0.987	0.000
D52 Folate deficiency anaemia	0.012	0.988	0.000
K11.8 Other diseases of salivary glands	0.012	0.988	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.012	0.988	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.012	0.988	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.012	0.988	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.012	0.988	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.012	0.988	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.012	0.988	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.012	0.988	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.012	0.988	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.012	0.988	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.000	0.989	0.011
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.011	0.989	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.011	0.989	0.000
K11.7 Disturbances of salivary secretion	0.011	0.989	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.011	0.989	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.011	0.989	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.011	0.989	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.011	0.989	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.011	0.989	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.011	0.989	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.011	0.989	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.011	0.989	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.011	0.989	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.000	0.990	0.010
K11.2 Sialoadenitis	0.010	0.990	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.990	0.010
K11.9 Disease of salivary gland, unspecified	0.010	0.990	0.000
K11.4 Fistula of salivary gland	0.009	0.991	0.000
K11.0 Atrophy of salivary gland	0.009	0.991	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.991	0.009
M21.39 Wrist or foot drop (acquired)-Site unspec	0.009	0.991	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.009	0.991	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.009	0.991	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.009	0.991	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.009	0.991	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.009	0.991	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.009	0.991	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.009	0.991	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.009	0.991	0.000
K11.6 Mucocele of salivary gland	0.009	0.991	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.991	0.009
D52.8 Other folate deficiency anaemias	0.009	0.991	0.000
D52.1 Drug-induced folate deficiency anaemia	0.009	0.991	0.000
D52.0 Dietary folate deficiency anaemia	0.009	0.991	0.000
K11.1 Hypertrophy of salivary gland	0.009	0.991	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.991	0.009
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.991	0.009
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.991	0.009
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.008	0.992	0.000
K11.3 Abscess of salivary gland	0.008	0.992	0.000
M25.78 Osteophyte (Other)	0.008	0.992	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.992	0.008
R93.6 Abnormal findings on diagnostic imaging of limbs	0.000	0.992	0.008
M25.76 Osteophyte (Lower leg)	0.007	0.993	0.000
M25.7 Osteophyte	0.007	0.993	0.000
D50.8 Other iron deficiency anaemias	0.007	0.993	0.000
M25.77 Osteophyte (Ankle and foot)	0.007	0.993	0.000
D52.9 Folate deficiency anaemia, unspecified	0.007	0.993	0.000
E87.2 Acidosis	0.000	0.993	0.007
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.993	0.007
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.007	0.993	0.000
M25.72 Osteophyte (Upper arm)	0.006	0.994	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.006	0.994	0.000
M25.73 Osteophyte (Forearm)	0.006	0.994	0.000
M25.79 Osteophyte (Site unspecified)	0.006	0.994	0.000
M25.74 Osteophyte (Hand)	0.005	0.994	0.000
M25.70 Osteophyte (Multiple sites)	0.005	0.995	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.995	0.005
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.005	0.995	0.000
N81.6 Rectocele	0.005	0.995	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.004	0.995	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.005	0.995	0.000
K86.2 Cyst of pancreas	0.000	0.996	0.004
S52.50 Fracture of lower end of radius (closed)	0.000	0.996	0.004
S27.0 Traumatic pneumothorax	0.004	0.996	0.000
R54 Senility	0.000	0.996	0.004
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.003	0.996	0.000
M25.71 Osteophyte (Shoulder region)	0.003	0.997	0.000
F06.7 Mild cognitive disorder	0.003	0.997	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.003	0.997	0.000
M79.79 Fibromyalgia (Site unspecified)	0.003	0.997	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.997	0.003
S52.5 Fracture of lower end of radius	0.000	0.997	0.003
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.997	0.003
S81.0 Open wound of knee	0.000	0.997	0.003
S52.20 Fracture of shaft of ulna (closed)	0.000	0.997	0.003
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.997	0.003
K86.9 Disease of pancreas, unspecified	0.000	0.997	0.003
M71.29 Synovial cyst of popliteal space [Baker]-Site unspec	0.002	0.997	0.000
M71.28 Synovial cyst of popliteal space [Baker]-Other	0.002	0.997	0.000
M71.27 Synovial cyst of popliteal space [Baker]-Ankle/Foot	0.002	0.997	0.000
M71.25 Synovial cyst of popliteal space [Baker]-Pelvic/Thigh	0.002	0.997	0.000
M71.24 Synovial cyst of popliteal space [Baker]-Hand	0.002	0.997	0.000
M71.23 Synovial cyst of popliteal space [Baker]-Forearm	0.002	0.997	0.000
M71.22 Synovial cyst of popliteal space [Baker]-Upper arm	0.002	0.997	0.000
M71.21 Synovial cyst of popliteal space [Baker]-Shldr region	0.002	0.997	0.000
M71.20 Synovial cyst of popliteal space [Baker]-Mult sites	0.002	0.997	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.997	0.003
E89.0 Postprocedural hypothyroidism	0.003	0.997	0.000
S52.2 Fracture of shaft of ulna	0.000	0.997	0.002
D09.0 Bladder	0.000	0.997	0.003
K86 Other diseases of pancreas	0.000	0.998	0.002
F12.1 Harmful use	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
I20.1 Angina pectoris with documented spasm	0.000	0.998	0.002
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
J98.0 Diseases of bronchus, not elsewhere classified	0.002	0.998	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.000	0.998	0.002
S52.10 Fracture of upper end of radius (closed)	0.000	0.998	0.002
S52 Fracture of forearm	0.000	0.998	0.002
S52.1 Fracture of upper end of radius	0.000	0.998	0.002
H44.2 Degenerative myopia	0.000	0.998	0.002
S81.8 Open wound of other parts of lower leg	0.000	0.998	0.002
S52.3 Fracture of shaft of radius	0.000	0.998	0.002
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.000	0.998	0.002
S52.21 Fracture of shaft of ulna (open)	0.000	0.998	0.002
M71.5 Other bursitis, not elsewhere classified	0.002	0.998	0.000
S52.0 Fracture of upper end of ulna	0.000	0.998	0.002
M71.56 Other bursitis, not elsewhere classified (Lower leg)	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
J98.9 Respiratory disorder, unspecified	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
S52.8 Fracture of other parts of forearm	0.000	0.998	0.002
S52.30 Fracture of shaft of radius (closed)	0.000	0.998	0.002
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.998	0.002
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
M71.55 Other bursitis, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
N21.0 Calculus in bladder	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
S52.9 Fracture of forearm, part unspecified	0.000	0.998	0.002
M71 Other bursopathies	0.002	0.998	0.000
S52.11 Fracture of upper end of radius (open)	0.000	0.998	0.002
S52.51 Fracture of lower end of radius (open)	0.000	0.998	0.002
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
S81 Open wound of lower leg	0.000	0.998	0.002
S52.01 Fracture of upper end of ulna (open)	0.000	0.998	0.002
S52.80 Fracture of other parts of forearm (closed)	0.000	0.998	0.002
S52.31 Fracture of shaft of radius (open)	0.000	0.998	0.002
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.002	0.998	0.000
F06.5 Organic dissociative disorder	0.002	0.998	0.000
F06.4 Organic anxiety disorder	0.002	0.998	0.000
F06.3 Organic mood [affective] disorders	0.002	0.998	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.002	0.998	0.000
F06.1 Organic catatonic disorder	0.002	0.998	0.000
F06.0 Organic hallucinosis	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
M71.59 Other bursitis, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M71.58 Other bursitis, not elsewhere classified (Other)	0.002	0.998	0.000
M71.57 Other bursitis, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M71.54 Other bursitis, not elsewhere classified (Hand)	0.002	0.998	0.000
M71.53 Other bursitis, not elsewhere classified (Forearm)	0.002	0.998	0.000
M71.52 Other bursitis, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M71.51 Other bursitis, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M71.50 Other bursitis, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
D11.0 Parotid gland	0.002	0.998	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
S83.3 Tear of articular cartilage of knee, current	0.000	0.998	0.002
S52.81 Fracture of other parts of forearm (open)	0.000	0.998	0.002
J98.4 Other disorders of lung	0.002	0.998	0.000
S27 Injury of other and unspecified intrathoracic organs	0.002	0.998	0.000
S83.1 Dislocation of knee	0.000	0.998	0.002
S83.0 Dislocation of patella	0.000	0.998	0.002
Y57.9 Drug or medicament, unspecified	0.000	0.998	0.002
S52.4 Fracture of shafts of both ulna and radius	0.000	0.998	0.002
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
H83.0 Labyrinthitis	0.000	0.998	0.002
M71.8 Other specified bursopathies	0.002	0.998	0.000
M71.4 Calcium deposit in bursa	0.002	0.998	0.000
M71.0 Abscess of bursa	0.002	0.998	0.000
R25.1 Tremor, unspecified	0.002	0.998	0.000
S52.91 Fracture of forearm, part unspecified (open)	0.000	0.998	0.001
S52.90 Fracture of forearm, part unspecified (closed)	0.000	0.998	0.001
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.998	0.000
M71.9 Bursopathy, unspecified	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
M71.37 Other bursal cyst (Ankle and foot)	0.001	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
J39.8 Other specified diseases of upper respiratory tract	0.000	0.998	0.002
M71.3 Other bursal cyst	0.001	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.001	0.998	0.000
S52.7 Multiple fractures of forearm	0.000	0.998	0.001
S83.7 Injury to multiple structures of knee	0.000	0.998	0.001
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.998	0.001
S92.50 Fracture of other toe (closed)	0.000	0.998	0.002
M79.7 Fibromyalgia	0.002	0.998	0.000
K76.8 Other specified diseases of liver	0.000	0.998	0.002
M71.1 Other infective bursitis	0.001	0.998	0.000
O64.1 Obstructed labour due to breech presentation	0.002	0.998	0.000
D84 Other immunodeficiencies	0.001	0.998	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.998	0.002
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.001	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.998	0.000
S27.9 Injury of unspecified intrathoracic organ	0.001	0.998	0.000
S27.7 Multiple injuries of intrathoracic organs	0.001	0.998	0.000
S27.6 Injury of pleura	0.001	0.998	0.000
S27.5 Injury of thoracic trachea	0.001	0.998	0.000
S27.4 Injury of bronchus	0.001	0.998	0.000
Y48.3 Local anaesthetics	0.000	0.998	0.001
S52.41 Fracture of shafts of both ulna and radius (open)	0.000	0.998	0.001
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.998	0.001
D80-D89 Certain disorders involving the immune mechanism	0.001	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.001	0.999	0.000
M71.09 Abscess of bursa (Site unspecified)	0.001	0.999	0.000
M71.08 Abscess of bursa (Other)	0.001	0.999	0.000
M71.07 Abscess of bursa (Ankle and foot)	0.001	0.999	0.000
M71.06 Abscess of bursa (Lower leg)	0.001	0.999	0.000
M71.05 Abscess of bursa (Pelvic region and thigh)	0.001	0.999	0.000
M71.04 Abscess of bursa (Hand)	0.001	0.999	0.000
M71.03 Abscess of bursa (Forearm)	0.001	0.999	0.000
M71.02 Abscess of bursa (Upper arm)	0.001	0.999	0.000
M71.01 Abscess of bursa (Shoulder region)	0.001	0.999	0.000
M71.00 Abscess of bursa (Multiple sites)	0.001	0.999	0.000
M71.16 Other infective bursitis (Lower leg)	0.001	0.999	0.000
M71.49 Calcium deposit in bursa (Site unspecified)	0.001	0.999	0.000
M71.48 Calcium deposit in bursa (Other)	0.001	0.999	0.000
M71.47 Calcium deposit in bursa (Ankle and foot)	0.001	0.999	0.000
M71.46 Calcium deposit in bursa (Lower leg)	0.001	0.999	0.000
M71.45 Calcium deposit in bursa (Pelvic region and thigh)	0.001	0.999	0.000
M71.44 Calcium deposit in bursa (Hand)	0.001	0.999	0.000
M71.43 Calcium deposit in bursa (Forearm)	0.001	0.999	0.000
M71.42 Calcium deposit in bursa (Upper arm)	0.001	0.999	0.000
M71.41 Calcium deposit in bursa (Shoulder region)	0.001	0.999	0.000
M71.40 Calcium deposit in bursa (Multiple sites)	0.001	0.999	0.000
M71.89 Other specified bursopathies (Site unspecified)	0.001	0.999	0.000
M71.88 Other specified bursopathies (Other)	0.001	0.999	0.000
M71.87 Other specified bursopathies (Ankle and foot)	0.001	0.999	0.000
M71.86 Other specified bursopathies (Lower leg)	0.001	0.999	0.000
M71.85 Other specified bursopathies (Pelvic region and thigh)	0.001	0.999	0.000
M71.84 Other specified bursopathies (Hand)	0.001	0.999	0.000
M71.83 Other specified bursopathies (Forearm)	0.001	0.999	0.000
M71.82 Other specified bursopathies (Upper arm)	0.001	0.999	0.000
M71.81 Other specified bursopathies (Shoulder region)	0.001	0.999	0.000
M71.80 Other specified bursopathies (Multiple sites)	0.001	0.999	0.000
M71.99 Bursopathy, unspecified (Site unspecified)	0.001	0.999	0.000
M71.98 Bursopathy, unspecified (Other)	0.001	0.999	0.000
M71.96 Bursopathy, unspecified (Lower leg)	0.001	0.999	0.000
M71.95 Bursopathy, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M71.94 Bursopathy, unspecified (Hand)	0.001	0.999	0.000
M71.93 Bursopathy, unspecified (Forearm)	0.001	0.999	0.000
M71.92 Bursopathy, unspecified (Upper arm)	0.001	0.999	0.000
M71.91 Bursopathy, unspecified (Shoulder region)	0.001	0.999	0.000
M71.90 Bursopathy, unspecified (Multiple sites)	0.001	0.999	0.000
Q60.0 Renal agenesis, unilateral	0.001	0.999	0.000
M71.34 Other bursal cyst (Hand)	0.001	0.999	0.000
M71.97 Bursopathy, unspecified (Ankle and foot)	0.001	0.999	0.000
T39.1 4-Aminophenol derivatives	0.001	0.999	0.000
M71.39 Other bursal cyst (Site unspecified)	0.001	0.999	0.000
M71.36 Other bursal cyst (Lower leg)	0.001	0.999	0.000
M71.35 Other bursal cyst (Pelvic region and thigh)	0.001	0.999	0.000
M71.33 Other bursal cyst (Forearm)	0.001	0.999	0.000
M71.32 Other bursal cyst (Upper arm)	0.001	0.999	0.000
M71.31 Other bursal cyst (Shoulder region)	0.001	0.999	0.000
M71.30 Other bursal cyst (Multiple sites)	0.001	0.999	0.000
M79.70 Fibromyalgia (Multiple sites)	0.001	0.999	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.001	0.999	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.999	0.001
D89.1 Cryoglobulinaemia	0.001	0.999	0.000
E78.4 Other hyperlipidaemia	0.000	0.999	0.001
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.999	0.001
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.999	0.001
T46.7 Peripheral vasodilators	0.000	0.999	0.001
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.999	0.001
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.999	0.001
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.999	0.001
S81.9 Open wound of lower leg, part unspecified	0.000	0.999	0.001
S81.7 Multiple open wounds of lower leg	0.000	0.999	0.001
D83 Common variable immunodeficiency	0.001	0.999	0.000
M71.19 Other infective bursitis (Site unspecified)	0.001	0.999	0.000
M71.18 Other infective bursitis (Other)	0.001	0.999	0.000
M71.17 Other infective bursitis (Ankle and foot)	0.001	0.999	0.000
M71.15 Other infective bursitis (Pelvic region and thigh)	0.001	0.999	0.000
M71.14 Other infective bursitis (Hand)	0.001	0.999	0.000
M71.13 Other infective bursitis (Forearm)	0.001	0.999	0.000
M71.11 Other infective bursitis (Shoulder region)	0.001	0.999	0.000
M71.10 Other infective bursitis (Multiple sites)	0.001	0.999	0.000
M79.78 Fibromyalgia (Other)	0.001	0.999	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.001	0.999	0.000
M79.76 Fibromyalgia (Lower leg)	0.001	0.999	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.001	0.999	0.000
M79.74 Fibromyalgia (Hand)	0.001	0.999	0.000
M79.73 Fibromyalgia (Forearm)	0.001	0.999	0.000
M79.72 Fibromyalgia (Upper arm)	0.001	0.999	0.000
M79.71 Fibromyalgia (Shoulder region)	0.001	0.999	0.000
E27.8 Other specified disorders of adrenal gland	0.001	0.999	0.000
K60.1 Chronic anal fissure	0.001	0.999	0.000
S27.2 Traumatic heamopneumothorax	0.001	0.999	0.000
D84.8 Other specified immunodeficiencies	0.001	0.999	0.000
D84.1 Defects in the complement system	0.001	0.999	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.000	0.999	0.001
Z87.0 Personal history of diseases of the respiratory system	0.000	0.999	0.001
D89.3 Immune reconstitution syndrome	0.001	0.999	0.000
I63.8 Other cerebral infarction	0.000	0.999	0.001
L40.5 Arthropathic psoriasis	0.001	0.999	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.999	0.001
Y83.9 Surgical procedure, unspecified	0.001	0.999	0.000
D82 Immunodeficiency associated with other major defects	0.001	0.999	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.001	0.999	0.000
D81 Combined immunodeficiencies	0.001	0.999	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.999	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.001	0.999	0.000
S27.1 Traumatic haemothorax	0.001	0.999	0.000
S52.6 Fracture of lower end of both ulna and radius	0.000	0.999	0.001
M43.02 Spondylolysis (Cervical region)	0.001	0.999	0.000
L40.8 Other psoriasis	0.001	0.999	0.000
S27.3 Other injuries of lung	0.001	0.999	0.000
T46.1 Calcium-channel blockers	0.000	0.999	0.001
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.000	0.999	0.001
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.999	0.000
M54.3 Sciatica	0.000	0.999	0.001
S52.71 Multiple fractures of forearm (open)	0.000	0.999	0.001
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.001	0.999	0.000
Y57.5 X-ray contrast media	0.000	0.999	0.001
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
D82.1 Di George's syndrome	0.001	0.999	0.000
R07.0 Pain in throat	0.001	0.999	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.000	0.999	0.001
S52.61 Fracture of lower end of both ulna and radius (open)	0.000	0.999	0.001
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.000	0.999	0.001
M43.09 Spondylolysis (Site unspecified)	0.001	0.999	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
C45.7 Mesothelioma of other sites	0.001	0.999	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.999	0.001
G57.6 Lesion of plantar nerve	0.001	0.999	0.000
D09 Carcinoma in situ of other and unspecified sites	0.000	0.999	0.001
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.001	0.999	0.000
S52.70 Multiple fractures of forearm (closed)	0.000	0.999	0.001
S92.51 Fracture of other toe (open)	0.000	0.999	0.001
H90.3 Sensorineural hearing loss, bilateral	0.000	0.999	0.001
M54.35 Sciatica (Thoracolumbar region)	0.000	0.999	0.001
M54.34 Sciatica-Thoracic	0.000	0.999	0.001
M54.33 Sciatica-Cervicothoracic	0.000	0.999	0.001
M54.32 Sciatica-Cervical	0.000	0.999	0.001
M54.31 Sciatica-Occipit-atl-axl	0.000	0.999	0.001
M54.30 Sciatica (Multiple sites in spine)	0.000	0.999	0.001
M71.12 Other infective bursitis (Upper arm)	0.001	0.999	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.000	0.999	0.001
M43.0 Spondylolysis	0.001	0.999	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.999	0.001
E28.2 Polycystic ovarian syndrome	0.001	0.999	0.000
G83.8 Other specified paralytic syndromes	0.000	0.999	0.001
H74.4 Polyp of middle ear	0.000	0.999	0.001
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.999	0.001
C45.0 Mesothelioma of pleura	0.001	0.999	0.000
D11.7 Other major salivary glands	0.001	0.999	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.999	0.001
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.001	0.999	0.000
C48.1 Specified parts of peritoneum	0.000	0.999	0.001
C49.0 Connective and soft tissue of head, face and neck	0.000	0.999	0.001
D09.9 Carcinoma in situ, unspecified	0.000	0.999	0.001
D09.7 Carcinoma in situ of other specified sites	0.000	0.999	0.001
D09.3 Thyroid and other endocrine glands	0.000	0.999	0.001
D09.2 Eye	0.000	0.999	0.001
D09.1 Other and unspecified urinary organs	0.000	0.999	0.001
K86.8 Other specified diseases of pancreas	0.000	0.999	0.001
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
X68.9 Unspecified place	0.000	0.999	0.001
G83.1 Monoplegia of lower limb	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations