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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16998069
log Bayes Factor = 3.34861
Chromosome 22   position 23,494,926  (GRCh37) Explore rs16998069 on Ensembl!
Variant rs16998069 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
# Top node
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.994 0.006 0.000
I20-I25 Ischaemic heart diseases
0.993 0.007 0.000
Chapter V Mental and behavioural disorders
0.989 0.011 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.987 0.013 0.000
S00-S09 Injuries to the head
0.985 0.015 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.980 0.020 0.000
I25 Chronic ischaemic heart disease
0.973 0.027 0.000
S01 Open wound of head
0.968 0.032 0.000
Chapter XX External causes of morbidity and mortality
0.948 0.052 0.000
I20 Angina pectoris
0.946 0.054 0.000
F60-F69 Disorders of adult personality and behaviour
0.944 0.056 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.941 0.059 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.934 0.066 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.930 0.070 0.000
S01.0 Open wound of scalp
0.926 0.074 0.000
O60-O75 Complications of labour and delivery
0.925 0.075 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.924 0.076 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.917 0.083 0.000
T43.2 Other and unspecified antidepressants
0.917 0.083 0.000
Chapter VI Diseases of the nervous system
0.913 0.087 0.000
S00 Superficial injury of head
0.912 0.088 0.000
F60 Specific personality disorders
0.912 0.088 0.000
I22 Subsequent myocardial infarction
0.900 0.100 0.000
Chapter XI Diseases of the digestive system
0.892 0.108 0.000
W00-W19 Falls
0.889 0.111 0.000
K90-K93 Other diseases of the digestive system
0.889 0.111 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.888 0.112 0.000
K92 Other diseases of digestive system
0.888 0.112 0.000
S01.2 Open wound of nose
0.886 0.114 0.000
Chapter XXI Factors influencing health status and contact with health services
0.884 0.116 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.878 0.122 0.000
O70 Perineal laceration during delivery
0.877 0.123 0.000
I20.0 Unstable angina
0.876 0.124 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.874 0.126 0.000
F60.9 Personality disorder, unspecified
0.865 0.135 0.000
T39.1 4-Aminophenol derivatives
0.861 0.139 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.860 0.140 0.000
K70-K77 Diseases of liver
0.858 0.142 0.000
O36 Maternal care for other known or suspected foetal problems
0.857 0.143 0.000
S00.8 Superficial injury of other parts of head
0.853 0.147 0.000
G40-G47 Episodic and paroxysmal disorders
0.853 0.147 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.849 0.151 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.844 0.156 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.842 0.158 0.000
G40 Epilepsy
0.840 0.160 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.837 0.163 0.000
I20.9 Angina pectoris, unspecified
0.837 0.163 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.833 0.167 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.831 0.169 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.828 0.172 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.827 0.173 0.000
G40.9 Epilepsy, unspecified
0.825 0.175 0.000
I95 Hypotension
0.819 0.181 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.819 0.181 0.000
I25.2 Old myocardial infarction
0.813 0.187 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.812 0.188 0.000
G90-G99 Other disorders of the nervous system
0.809 0.191 0.000
T66-T78 Other and unspecified effects of external causes
0.805 0.195 0.000
K75 Other inflammatory liver diseases
0.805 0.195 0.000
Z04 Examination and observation for other reasons
0.799 0.201 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.799 0.201 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.794 0.206 0.000
F60.3 Emotionally unstable personality disorder
0.785 0.215 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.782 0.218 0.000
O36.6 Maternal care for excessive foetal growth
0.774 0.226 0.000
I95.1 Orthostatic hypotension
0.773 0.226 0.000
F99-F99 Unspecified mental disorder
0.773 0.227 0.000
F41 Other anxiety disorders
0.771 0.229 0.000
O40 Polyhydramnios
0.771 0.229 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.771 0.229 0.000
O66 Other obstructed labour
0.771 0.229 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.769 0.231 0.000
S40-S49 Injuries to the shoulder and upper arm
0.767 0.233 0.000
O70.0 First degree perineal laceration during delivery
0.763 0.237 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.763 0.237 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.762 0.238 0.000
O43 Placental disorders
0.760 0.240 0.000
Chapter XXII Codes for special purposes
0.760 0.240 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.759 0.241 0.000
O36.9 Maternal care for foetal problem, unspecified
0.758 0.242 0.000
V10-V19 Pedal cyclist injured in transport accident
0.755 0.245 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.754 0.246 0.000
I21 Acute myocardial infarction
0.754 0.246 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.753 0.247 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.753 0.247 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.752 0.248 0.000
O47 False labour
0.751 0.249 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.751 0.249 0.000
X60-X84 Intentional self-harm
0.751 0.249 0.000
O70.2 Third degree perineal laceration during delivery
0.750 0.250 0.000
T39.0 Salicylates
0.745 0.254 0.000
S01.5 Open wound of lip and oral cavity
0.745 0.255 0.000
I05-I09 Chronic rheumatic heart diseases
0.745 0.255 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.744 0.256 0.000
I20.1 Angina pectoris with documented spasm
0.742 0.258 0.000
M20-M25 Other joint disorders
0.741 0.259 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.741 0.259 0.000
W19 Unspecified fall
0.740 0.260 0.000
O62 Abnormalities of forces of labour
0.740 0.260 0.000
S50-S59 Injuries to the elbow and forearm
0.738 0.262 0.000
W10 Fall on and from stairs and steps
0.737 0.263 0.000
S10-S19 Injuries to the neck
0.736 0.264 0.000
S00.3 Superficial injury of nose
0.736 0.264 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.735 0.265 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.734 0.265 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.734 0.266 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.733 0.267 0.000
F10.0 Acute intoxication
0.733 0.267 0.000
K70 Alcoholic liver disease
0.732 0.268 0.000
Z04.8 Examination and observation for other specified reasons
0.730 0.270 0.000
F41.2 Mixed anxiety and depressive disorder
0.729 0.271 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.728 0.272 0.000
K92.9 Disease of digestive system, unspecified
0.726 0.274 0.000
T42.4 Benzodiazepines
0.726 0.274 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.724 0.276 0.000
K92.0 Haematemesis
0.723 0.277 0.000
K76 Other diseases of liver
0.723 0.277 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.722 0.278 0.000
F30-F39 Mood [affective] disorders
0.722 0.278 0.000
O44 Placenta praevia
0.721 0.279 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.720 0.280 0.000
T79-T79 Certain early complications of trauma
0.720 0.280 0.000
W15 Fall from cliff
0.719 0.281 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.718 0.282 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.717 0.283 0.000
Z13 Special screening examination for other diseases and disorders
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.716 0.284 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.716 0.284 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
T36 Poisoning by systemic antibiotics
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.713 0.287 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.713 0.287 0.000
I60-I69 Cerebrovascular diseases
0.713 0.287 0.000
I00-I02 Acute rheumatic fever
0.713 0.287 0.000
I23 Certain current complications following acute myocardial infarction
0.712 0.288 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.712 0.288 0.000
M25 Other joint disorders, not elsewhere classified
0.711 0.289 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
F80-F89 Disorders of psychological development
0.709 0.291 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
O85-O92 Complications predominantly related to the puerperium
0.708 0.292 0.000
S01.9 Open wound of head, part unspecified
0.706 0.293 0.000
S08 Traumatic amputation of part of head
0.706 0.294 0.000
S07 Crushing injury of head
0.706 0.294 0.000
S05 Injury of eye and orbit
0.706 0.294 0.000
S04 Injury of cranial nerves
0.706 0.294 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.706 0.294 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.706 0.294 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.703 0.297 0.000
T43.9 Psychotropic drug, unspecified
0.702 0.298 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.702 0.298 0.000
T43.6 Psychostimulants with abuse potential
0.702 0.298 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.702 0.298 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.702 0.298 0.000
S06 Intracranial injury
0.702 0.298 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.699 0.301 0.000
O61 Failed induction of labour
0.699 0.301 0.000
I25.6 Silent myocardial ischaemia
0.697 0.302 0.000
I25.4 Coronary artery aneurysm
0.697 0.302 0.000
I25.3 Aneurysm of heart
0.697 0.302 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.697 0.302 0.000
I24 Other acute ischaemic heart diseases
0.697 0.303 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.696 0.304 0.000
S01.7 Multiple open wounds of head
0.694 0.306 0.000
S01.4 Open wound of cheek and temporomandibular area
0.694 0.306 0.000
S01.3 Open wound of ear
0.694 0.306 0.000
S90-S99 Injuries to the ankle and foot
0.694 0.306 0.000
O70.1 Second degree perineal laceration during delivery
0.692 0.308 0.000
F43 Reaction to severe stress, and adjustment disorders
0.692 0.308 0.000
G91 Hydrocephalus
0.690 0.310 0.000
S00.7 Multiple superficial injuries of head
0.690 0.310 0.000
T51 Toxic effect of alcohol
0.689 0.311 0.000
K75.8 Other specified inflammatory liver diseases
0.689 0.311 0.000
Z03.1 Observation for suspected malignant neoplasm
0.688 0.312 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.686 0.314 0.000
O70.9 Perineal laceration during delivery, unspecified
0.686 0.314 0.000
O73 Retained placenta and membranes, without haemorrhage
0.685 0.315 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.684 0.316 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.684 0.316 0.000
S20-S29 Injuries to the thorax
0.683 0.316 0.000
W13 Fall from, out of or through building or structure
0.683 0.317 0.000
O42 Premature rupture of membranes
0.683 0.317 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.683 0.317 0.000
V20-V29 Motorcycle rider injured in transport accident
0.682 0.318 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.681 0.319 0.000
S01.1 Open wound of eyelid and periocular area
0.680 0.320 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.680 0.320 0.000
Y35-Y36 Legal intervention and operations of war
0.680 0.320 0.000
Y10-Y34 Event of undetermined intent
0.680 0.320 0.000
Y00-Y09 Assault
0.680 0.320 0.000
X85-X99 Assault
0.680 0.320 0.000
X50-X57 Overexertion, travel and privation
0.680 0.320 0.000
X30-X39 Exposure to forces of nature
0.680 0.320 0.000
X10-X19 Contact with heat and hot substances
0.680 0.320 0.000
X00-X09 Exposure to smoke, fire and flames
0.680 0.320 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.680 0.320 0.000
W75-W84 Other accidental threats to breathing
0.680 0.320 0.000
W65-W74 Accidental drowning and submersion
0.680 0.320 0.000
W50-W64 Exposure to animate mechanical forces
0.680 0.320 0.000
V98-V99 Other and unspecified transport accidents
0.680 0.320 0.000
V95-V97 Air and space transport accidents
0.680 0.320 0.000
V90-V94 Water transport accidents
0.680 0.320 0.000
V80-V89 Other land transport accidents
0.680 0.320 0.000
V70-V79 Bus occupant injured in transport accident
0.680 0.320 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.680 0.320 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.680 0.320 0.000
V40-V49 Car occupant injured in transport accident
0.680 0.320 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.680 0.320 0.000
V01-V09 Pedestrian injured in transport accident
0.680 0.320 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.679 0.321 0.000
S00.9 Superficial injury of head, part unspecified
0.678 0.322 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.677 0.322 0.000
F68 Other disorders of adult personality and behaviour
0.677 0.323 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.677 0.323 0.000
F65 Disorders of sexual preference
0.677 0.323 0.000
F64 Gender identity disorders
0.677 0.323 0.000
F63 Habit and impulse disorders
0.677 0.323 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.677 0.323 0.000
F69 Unspecified disorder of adult personality and behaviour
0.677 0.323 0.000
F61 Mixed and other personality disorders
0.677 0.323 0.000
K12 Stomatitis and related lesions
0.677 0.323 0.000
O00-O08 Pregnancy with abortive outcome
0.676 0.324 0.000
O45 Premature separation of placenta [abruptio placentae]
0.674 0.325 0.000
O41 Other disorders of amniotic fluid and membranes
0.674 0.325 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.674 0.325 0.000
O33 Maternal care for known or suspected disproportion
0.674 0.325 0.000
O31 Complications specific to multiple gestation
0.674 0.325 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.673 0.327 0.000
S32 Fracture of lumbar spine and pelvis
0.672 0.328 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.672 0.328 0.000
G95 Other diseases of spinal cord
0.672 0.328 0.000
T40.2 Other opioids
0.671 0.329 0.000
O30 Multiple gestation
0.670 0.330 0.000
K75.4 Autoimmune hepatitis
0.670 0.330 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.669 0.331 0.000
Z29 Need for other prophylactic measures
0.669 0.331 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.669 0.331 0.000
O24 Diabetes mellitus in pregnancy
0.669 0.331 0.000
K00 Disorders of tooth development and eruption
0.669 0.331 0.000
G20-G26 Extrapyramidal and movement disorders
0.667 0.333 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.667 0.333 0.000
O23 Infections of genito-urinary tract in pregnancy
0.666 0.334 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.666 0.334 0.000
T78 Adverse effects, not elsewhere classified
0.666 0.334 0.000
W19.9 Unspecified place
0.663 0.337 0.000
O74 Complications of anaesthesia during labour and delivery
0.663 0.337 0.000
O71 Other obstetric trauma
0.663 0.337 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.663 0.337 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.663 0.337 0.000
O60 Preterm delivery
0.663 0.337 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.662 0.337 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.662 0.337 0.000
T39.4 Antirheumatics, not elsewhere classified
0.662 0.337 0.000
T39.2 Pyrazolone derivatives
0.662 0.337 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.660 0.339 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.660 0.340 0.000
M20 Acquired deformities of fingers and toes
0.659 0.341 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.658 0.342 0.000
I99 Other and unspecified disorders of circulatory system
0.658 0.342 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.657 0.343 0.000
F10.2 Dependence syndrome
0.655 0.345 0.000
S70-S79 Injuries to the hip and thigh
0.655 0.345 0.000
M25.7 Osteophyte
0.655 0.345 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.655 0.345 0.000
G70-G73 Diseases of myoneural junction and muscle
0.654 0.346 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.654 0.346 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.654 0.346 0.000
K75.9 Inflammatory liver disease, unspecified
0.654 0.346 0.000
S00.5 Superficial injury of lip and oral cavity
0.654 0.346 0.000
S00.4 Superficial injury of ear
0.654 0.346 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.654 0.346 0.000
F60.8 Other specific personality disorders
0.654 0.346 0.000
F60.7 Dependent personality disorder
0.654 0.346 0.000
F60.6 Anxious [avoidant] personality disorder
0.654 0.346 0.000
F60.5 Anankastic personality disorder
0.654 0.346 0.000
F60.4 Histrionic personality disorder
0.654 0.346 0.000
F60.2 Dissocial personality disorder
0.654 0.346 0.000
F60.1 Schizoid personality disorder
0.654 0.346 0.000
F60.0 Paranoid personality disorder
0.654 0.346 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.653 0.347 0.000
Z13.9 Special screening examination, unspecified
0.651 0.349 0.000
F45 Somatoform disorders
0.650 0.350 0.000
M21 Other acquired deformities of limbs
0.648 0.352 0.000
G93 Other disorders of brain
0.645 0.355 0.000
I22.8 Subsequent myocardial infarction of other sites
0.645 0.355 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.645 0.355 0.000
K90 Intestinal malabsorption
0.645 0.355 0.000
I61 Intracerebral haemorrhage
0.638 0.362 0.000
W18 Other fall on same level
0.638 0.362 0.000
W17 Other fall from one level to another
0.638 0.362 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.638 0.362 0.000
W14 Fall from tree
0.638 0.362 0.000
W12 Fall on and from scaffolding
0.638 0.362 0.000
W11 Fall on and from ladder
0.638 0.362 0.000
W09 Fall involving playground equipment
0.638 0.362 0.000
W08 Fall involving other furniture
0.638 0.362 0.000
W07 Fall involving chair
0.638 0.362 0.000
W05 Fall involving wheelchair
0.638 0.362 0.000
W04 Fall while being carried or supported by other persons
0.638 0.362 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.638 0.362 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.638 0.362 0.000
W00 Fall on same level involving ice and snow
0.638 0.362 0.000
K70.9 Alcoholic liver disease, unspecified
0.637 0.362 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.637 0.363 0.000
K92.8 Other specified diseases of digestive system
0.637 0.363 0.000
S01.8 Open wound of other parts of head
0.636 0.364 0.000
S80-S89 Injuries to the knee and lower leg
0.635 0.365 0.000
S42 Fracture of shoulder and upper arm
0.635 0.365 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.633 0.367 0.000
Y52 Agents primarily affecting the cardiovascular system
0.633 0.367 0.000
T63 Toxic effect of contact with venomous animals
0.632 0.368 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.631 0.369 0.000
Z10 Routine general health check-up of defined subpopulation
0.629 0.371 0.000
I25.5 Ischaemic cardiomyopathy
0.629 0.371 0.000
O70.3 Fourth degree perineal laceration during delivery
0.629 0.371 0.000
M05-M14 Inflammatory polyarthropathies
0.629 0.371 0.000
O46.9 Antepartum haemorrhage, unspecified
0.629 0.371 0.000
M20.2 Hallux rigidus
0.629 0.371 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.628 0.372 0.000
W10.8 Other specified place
0.627 0.373 0.000
F48 Other neurotic disorders
0.627 0.373 0.000
F44 Dissociative [conversion] disorders
0.627 0.373 0.000
F42 Obsessive-compulsive disorder
0.627 0.373 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.623 0.377 0.000
K35-K38 Diseases of appendix
0.622 0.377 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.622 0.378 0.000
S02 Fracture of skull and facial bones
0.621 0.379 0.000
I80 Phlebitis and thrombophlebitis
0.621 0.379 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.621 0.379 0.000
I85 Oesophageal varices
0.619 0.381 0.000
K76.7 Hepatorenal syndrome
0.619 0.381 0.000
F99 Mental disorder, not otherwise specified
0.619 0.381 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.617 0.383 0.000
T40.4 Other synthetic narcotics
0.617 0.383 0.000
K12.1 Other forms of stomatitis
0.617 0.383 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.617 0.383 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.617 0.383 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.617 0.383 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.617 0.383 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.617 0.383 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.617 0.383 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.617 0.383 0.000
F11 Mental and behavioural disorders due to use of opioids
0.617 0.383 0.000
K77 Liver disorders in diseases classified elsewhere
0.615 0.385 0.000
K73 Chronic hepatitis, not elsewhere classified
0.615 0.385 0.000
K71 Toxic liver disease
0.615 0.385 0.000
I60 Subarachnoid haemorrhage
0.615 0.385 0.000
K75.0 Abscess of liver
0.615 0.385 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.614 0.386 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.614 0.386 0.000
O36.4 Maternal care for intra-uterine death
0.614 0.386 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.614 0.386 0.000
O36.2 Maternal care for hydrops foetalis
0.614 0.386 0.000
O36.1 Maternal care for other isoimmunisation
0.614 0.386 0.000
W06 Fall involving bed
0.614 0.386 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.614 0.386 0.000
Z00.0 General medical examination
0.614 0.386 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.612 0.388 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.611 0.389 0.000
G41 Status epilepticus
0.611 0.389 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.611 0.389 0.000
O62.0 Primary inadequate contractions
0.610 0.390 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.607 0.393 0.000
O29 Complications of anaesthesia during pregnancy
0.605 0.395 0.000
O28 Abnormal findings on antenatal screening of mother
0.605 0.395 0.000
O22 Venous complications in pregnancy
0.605 0.395 0.000
O21 Excessive vomiting in pregnancy
0.605 0.395 0.000
O25 Malnutrition in pregnancy
0.605 0.395 0.000
G30-G32 Other degenerative diseases of the nervous system
0.604 0.396 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.603 0.397 0.000
F10.3 Withdrawal state
0.603 0.397 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.603 0.397 0.000
G40.8 Other epilepsy
0.602 0.398 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.602 0.398 0.000
G40.5 Special epileptic syndromes
0.602 0.398 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.602 0.398 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.602 0.398 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.602 0.398 0.000
O43.8 Other placental disorders
0.601 0.399 0.000
T50.8 Diagnostic agents
0.600 0.400 0.000
T50.7 Analeptics and opioid receptor antagonists
0.600 0.400 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.600 0.400 0.000
T50.5 Appetite depressants
0.600 0.400 0.000
T50.4 Drugs affecting uric acid metabolism
0.600 0.400 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.600 0.400 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.600 0.400 0.000
T50.1 Loop [high-ceiling] diuretics
0.600 0.400 0.000
T50.0 Mineralocorticoids and their antagonists
0.600 0.400 0.000
Z04.9 Examination and observation for unspecified reason
0.599 0.401 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.597 0.402 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.597 0.402 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.597 0.402 0.000
T42.3 Barbiturates
0.597 0.402 0.000
T42.2 Succinimides and oxazolidinediones
0.597 0.402 0.000
T42.1 Iminostilbenes
0.597 0.402 0.000
T42.0 Hydantoin derivatives
0.597 0.402 0.000
W15.8 Other specified place
0.597 0.403 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.596 0.404 0.000
T65 Toxic effect of other and unspecified substances
0.596 0.404 0.000
T62 Toxic effect of other noxious substances eaten as food
0.596 0.404 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.596 0.404 0.000
T60 Toxic effect of pesticides
0.596 0.404 0.000
T59 Toxic effect of other gases, fumes and vapours
0.596 0.404 0.000
T57 Toxic effect of other inorganic substances
0.596 0.404 0.000
T56 Toxic effect of metals
0.596 0.404 0.000
T54 Toxic effect of corrosive substances
0.596 0.404 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.596 0.404 0.000
T52 Toxic effect of organic solvents
0.596 0.404 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.596 0.404 0.000
T58 Toxic effect of carbon monoxide
0.596 0.404 0.000
T55 Toxic effect of soaps and detergents
0.596 0.404 0.000
O26.8 Other specified pregnancy-related conditions
0.596 0.404 0.000
F33 Recurrent depressive disorder
0.595 0.405 0.000
S41 Open wound of shoulder and upper arm
0.594 0.406 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.593 0.407 0.000
O97 Death from sequelae of direct obstetric causes
0.593 0.407 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.593 0.407 0.000
O95 Obstetric death of unspecified cause
0.593 0.407 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.593 0.407 0.000
K65-K67 Diseases of peritoneum
0.593 0.407 0.000
T51.0 Ethanol
0.592 0.408 0.000
Z29.1 Prophylactic immunotherapy
0.591 0.409 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.590 0.410 0.000
Z03.4 Observation for suspected myocardial infarction
0.589 0.411 0.000
Q80-Q89 Other congenital malformations
0.589 0.411 0.000
Z04.3 Examination and observation following other accident
0.588 0.412 0.000
I95.8 Other hypotension
0.587 0.413 0.000
I95.0 Idiopathic hypotension
0.587 0.413 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.587 0.413 0.000
T40.8 Lysergide [LSD]
0.587 0.413 0.000
T40.7 Cannabis (derivatives)
0.587 0.413 0.000
T40.6 Other and unspecified narcotics
0.587 0.413 0.000
T40.5 Cocaine
0.587 0.413 0.000
T40.3 Methadone
0.587 0.413 0.000
T40.1 Heroin
0.587 0.413 0.000
T40.0 Opium
0.587 0.413 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.586 0.414 0.000
O43.1 Malformation of placenta
0.586 0.414 0.000
I05 Rheumatic mitral valve diseases
0.584 0.416 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.584 0.416 0.000
Z72 Problems related to lifestyle
0.584 0.416 0.000
K10 Other diseases of jaws
0.584 0.416 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.582 0.418 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.582 0.418 0.000
S37 Injury of urinary and pelvic organs
0.582 0.418 0.000
S36 Injury of intra-abdominal organs
0.582 0.418 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.582 0.418 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.582 0.418 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.582 0.418 0.000
S31 Open wound of abdomen, lower back and pelvis
0.582 0.418 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.582 0.418 0.000
F40 Phobic anxiety disorders
0.581 0.418 0.000
Y85 Sequelae of transport accidents
0.581 0.419 0.000
S00.1 Contusion of eyelid and periocular area
0.581 0.419 0.000
M20.4 Other hammer toe(s) (acquired)
0.580 0.420 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.580 0.420 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.580 0.420 0.000
G90 Disorders of autonomic nervous system
0.580 0.420 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.580 0.420 0.000
G92 Toxic encephalopathy
0.580 0.420 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.579 0.420 0.000
G47 Sleep disorders
0.579 0.421 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.579 0.421 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.579 0.421 0.000
M24 Other specific joint derangements
0.578 0.422 0.000
S00.0 Superficial injury of scalp
0.578 0.422 0.000
T75 Effects of other external causes
0.577 0.423 0.000
T74 Maltreatment syndromes
0.577 0.423 0.000
T73 Effects of other deprivation
0.577 0.423 0.000
T70 Effects of air pressure and water pressure
0.577 0.423 0.000
T69 Other effects of reduced temperature
0.577 0.423 0.000
T67 Effects of heat and light
0.577 0.423 0.000
T71 Asphyxiation
0.577 0.423 0.000
T68 Hypothermia
0.577 0.423 0.000
T66 Unspecified effects of radiation
0.577 0.423 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.577 0.423 0.000
K75.2 Nonspecific reactive hepatitis
0.577 0.423 0.000
K75.1 Phlebitis of portal vein
0.577 0.423 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.576 0.424 0.000
I86 Varicose veins of other sites
0.575 0.425 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.574 0.426 0.000
M91-M94 Chondropathies
0.574 0.426 0.000
Z04.6 General psychiatric examination, requested by authority
0.573 0.427 0.000
Z04.5 Examination and observation following other inflicted injury
0.573 0.427 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.573 0.427 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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