TreeWAS – Variant ID: rs17030434

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O26.8 Other specified pregnancy-related conditions	0.085	0.915	0.000
C50.2 Upper-inner quadrant of breast	0.000	0.915	0.085
C50.8 Overlapping lesion of breast	0.000	0.917	0.083
O26 Maternal care for other conditions predominantly related to pregnancy	0.082	0.918	0.000
C50 Malignant neoplasm of breast	0.000	0.920	0.080
O26.9 Pregnancy-related condition, unspecified	0.080	0.920	0.000
C50.3 Lower-inner quadrant of breast	0.000	0.923	0.077
C50.1 Central portion of breast	0.000	0.928	0.072
O20-O29 Other maternal disorders predominantly related to pregnancy	0.066	0.934	0.000
O26.5 Maternal hypotension syndrome	0.065	0.935	0.000
O21 Excessive vomiting in pregnancy	0.061	0.939	0.000
O26.2 Pregnancy care of habitual aborter	0.060	0.939	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.059	0.941	0.000
O26.4 Herpes gestationis	0.059	0.941	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.059	0.941	0.000
O26.1 Low weight gain in pregnancy	0.059	0.941	0.000
O26.0 Excessive weight gain in pregnancy	0.059	0.941	0.000
O23 Infections of genito-urinary tract in pregnancy	0.058	0.942	0.000
O21.0 Mild hyperemesis gravidarum	0.053	0.947	0.000
O24 Diabetes mellitus in pregnancy	0.052	0.948	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.051	0.949	0.000
O21.9 Vomiting of pregnancy, unspecified	0.049	0.951	0.000
O29 Complications of anaesthesia during pregnancy	0.048	0.952	0.000
O25 Malnutrition in pregnancy	0.048	0.952	0.000
O28 Abnormal findings on antenatal screening of mother	0.048	0.952	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.047	0.953	0.000
C50.6 Axillary tail of breast	0.000	0.953	0.047
O23.4 Unspecified infection of urinary tract in pregnancy	0.046	0.954	0.000
O22 Venous complications in pregnancy	0.046	0.954	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.046	0.954	0.000
O21.2 Late vomiting of pregnancy	0.045	0.954	0.000
C50.5 Lower-outer quadrant of breast	0.000	0.955	0.045
O21.8 Other vomiting complicating pregnancy	0.044	0.956	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.042	0.958	0.000
O23.2 Infections of urethra in pregnancy	0.042	0.958	0.000
O23.1 Infections of bladder in pregnancy	0.042	0.958	0.000
O23.0 Infections of kidney in pregnancy	0.042	0.958	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.041	0.959	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.039	0.961	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.038	0.962	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.038	0.962	0.000
C50.4 Upper-outer quadrant of breast	0.000	0.962	0.038
O24.3 Pre-existing diabetes mellitus, unspecified	0.038	0.962	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.038	0.962	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.038	0.962	0.000
O23.5 Infections of the genital tract in pregnancy	0.036	0.963	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.034	0.965	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.034	0.965	0.000
O29.6 Failed or difficult intubation during pregnancy	0.034	0.965	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.034	0.965	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.034	0.965	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.034	0.965	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.034	0.965	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.034	0.965	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.034	0.965	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.034	0.966	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.034	0.966	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.034	0.966	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.034	0.966	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.034	0.966	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.034	0.966	0.000
C50-C50 Malignant neoplasm of breast	0.000	0.966	0.034
O22.0 Varicose veins of lower extremity in pregnancy	0.033	0.967	0.000
O22.9 Venous complication in pregnancy, unspecified	0.033	0.967	0.000
O22.8 Other venous complications in pregnancy	0.033	0.967	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.033	0.967	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.033	0.967	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.033	0.967	0.000
O22.1 Genital varices in pregnancy	0.033	0.967	0.000
O22.4 Haemorrhoids in pregnancy	0.031	0.969	0.000
O20 Haemorrhage in early pregnancy	0.030	0.970	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.029	0.970	0.000
C50.0 Nipple and areola	0.000	0.971	0.029
C50.9 Breast, unspecified	0.000	0.973	0.027
Chapter XV Pregnancy, childbirth and the puerperium	0.023	0.977	0.000
O20.8 Other haemorrhage in early pregnancy	0.022	0.978	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.022	0.978	0.000
O85-O92 Complications predominantly related to the puerperium	0.021	0.979	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.021	0.979	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.020	0.980	0.000
O00-O08 Pregnancy with abortive outcome	0.020	0.980	0.000
O04 Medical abortion	0.019	0.981	0.000
O16 Unspecified maternal hypertension	0.018	0.982	0.000
O90 Complications of the puerperium, not elsewhere classified	0.018	0.982	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.017	0.983	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.017	0.983	0.000
O86 Other puerperal infections	0.017	0.983	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.016	0.984	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.016	0.984	0.000
O87 Venous complications in the puerperium	0.016	0.984	0.000
O04.4 Incomplete, without complication	0.016	0.984	0.000
O15 Eclampsia	0.016	0.984	0.000
O00 Ectopic pregnancy	0.016	0.984	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.016	0.984	0.000
O86.4 Pyrexia of unknown origin following delivery	0.016	0.984	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.015	0.985	0.000
O14.0 Moderate preeclampsia	0.015	0.985	0.000
O91 Infections of breast associated with childbirth	0.015	0.985	0.000
O88 Obstetric embolism	0.015	0.985	0.000
O90.2 Haematoma of obstetric wound	0.015	0.985	0.000
O85 Puerperal sepsis	0.015	0.985	0.000
O07 Failed attempted abortion	0.015	0.985	0.000
O06 Unspecified abortion	0.015	0.985	0.000
O05 Other abortion	0.015	0.985	0.000
O01 Hydatidiform mole	0.015	0.985	0.000
O89 Complications of anaesthesia during the puerperium	0.015	0.985	0.000
J93.9 Pneumothorax, unspecified	0.000	0.985	0.015
O90.8 Other complications of the puerperium, not elsewhere classified	0.015	0.985	0.000
O90.9 Complication of the puerperium, unspecified	0.015	0.985	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.014	0.986	0.000
O14.1 Severe preeclampsia	0.014	0.986	0.000
O00.1 Tubal pregnancy	0.014	0.986	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.014	0.986	0.000
O04.7 Complete or unspecified, complicated by embolism	0.014	0.986	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.014	0.986	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.014	0.986	0.000
O04.3 Incomplete, with other and unspecified complications	0.014	0.986	0.000
O04.2 Incomplete, complicated by embolism	0.014	0.986	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.014	0.986	0.000
O02 Other abnormal products of conception	0.014	0.986	0.000
O90.5 Postpartum thyroiditis	0.013	0.987	0.000
O90.4 Postpartum acute renal failure	0.013	0.987	0.000
O90.3 Cardiomyopathy in the puerperium	0.013	0.987	0.000
O90.0 Disruption of Caesarean section wound	0.013	0.987	0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.013	0.987	0.000
O90.1 Disruption of perineal obstetric wound	0.013	0.987	0.000
O03 Spontaneous abortion	0.013	0.987	0.000
O87.8 Other venous complications in the puerperium	0.013	0.987	0.000
O86.1 Other infection of genital tract following delivery	0.013	0.987	0.000
O14.2 HELLP syndrome	0.013	0.987	0.000
O86.8 Other specified puerperal infections	0.012	0.987	0.000
O86.3 Other genito-urinary tract infections following delivery	0.012	0.987	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.012	0.988	0.000
O86.0 Infection of obstetric surgical wound	0.012	0.988	0.000
E23.0 Hypopituitarism	0.000	0.988	0.012
R41.0 Disorientation, unspecified	0.000	0.988	0.012
O04.9 Complete or unspecified, without complication	0.012	0.988	0.000
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.012	0.988	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.012	0.988	0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.012	0.988	0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.012	0.988	0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.012	0.988	0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.012	0.988	0.000
O08.3 Shock following abortion and ectopic and molar pregnancy	0.012	0.988	0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.012	0.988	0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.012	0.988	0.000
O87.9 Venous complication in the puerperium, unspecified	0.012	0.988	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.012	0.988	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.012	0.988	0.000
O92.1 Cracked nipple associated with childbirth	0.012	0.988	0.000
O15.9 Eclampsia, unspecified as to time period	0.012	0.988	0.000
O15.2 Eclampsia in the puerperium	0.012	0.988	0.000
O15.1 Eclampsia in labour	0.012	0.988	0.000
O15.0 Eclampsia in pregnancy	0.012	0.988	0.000
O00.8 Other ectopic pregnancy	0.012	0.988	0.000
O00.2 Ovarian pregnancy	0.012	0.988	0.000
O00.0 Abdominal pregnancy	0.012	0.988	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O92.7 Other and unspecified disorders of lactation	0.011	0.989	0.000
O92.6 Galactorrhoea	0.011	0.989	0.000
O92.5 Suppressed lactation	0.011	0.989	0.000
O92.4 Hypogalactia	0.011	0.989	0.000
O92.3 Agalactia	0.011	0.989	0.000
O92.0 Retracted nipple associated with childbirth	0.011	0.989	0.000
O88.8 Other obstetric embolism	0.011	0.989	0.000
O88.3 Obstetric pyaemic and septic embolism	0.011	0.989	0.000
O88.2 Obstetric blood-clot embolism	0.011	0.989	0.000
O88.1 Amniotic fluid embolism	0.011	0.989	0.000
O88.0 Obstetric air embolism	0.011	0.989	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.011	0.989	0.000
O91.1 Abscess of breast associated with childbirth	0.011	0.989	0.000
O91.0 Infection of nipple associated with childbirth	0.011	0.989	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.011	0.989	0.000
O86.2 Urinary tract infection following delivery	0.011	0.989	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O03.3 Incomplete, with other and unspecified complications	0.011	0.989	0.000
O01.9 Hydatidiform mole, unspecified	0.011	0.989	0.000
O01.1 Incomplete and partial hydatidiform mole	0.011	0.989	0.000
O01.0 Classical hydatidiform mole	0.011	0.989	0.000
O05.9 Complete or unspecified, without complication	0.011	0.989	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.011	0.989	0.000
O05.7 Complete or unspecified, complicated by embolism	0.011	0.989	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.011	0.989	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.011	0.989	0.000
O05.4 Incomplete, without complication	0.011	0.989	0.000
O05.3 Incomplete, with other and unspecified complications	0.011	0.989	0.000
O05.2 Incomplete, complicated by embolism	0.011	0.989	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.011	0.989	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.011	0.989	0.000
O06.9 Complete or unspecified, without complication	0.011	0.989	0.000
O06.8 Complete or unspecified, with other and unspecified complications	0.011	0.989	0.000
O06.7 Complete or unspecified, complicated by embolism	0.011	0.989	0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.011	0.989	0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.011	0.989	0.000
O06.4 Incomplete, without complication	0.011	0.989	0.000
O06.3 Incomplete, with other and unspecified complications	0.011	0.989	0.000
O06.2 Incomplete, complicated by embolism	0.011	0.989	0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.011	0.989	0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.011	0.989	0.000
O07.9 Other and unspecified failed attempted abortion, without complication	0.011	0.989	0.000
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.011	0.989	0.000
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.011	0.989	0.000
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.011	0.989	0.000
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.011	0.989	0.000
O07.4 Failed medical abortion, without complication	0.011	0.989	0.000
O07.3 Failed medical abortion, with other and unspecified complications	0.011	0.989	0.000
O07.2 Failed medical abortion, complicated by embolism	0.011	0.989	0.000
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.011	0.989	0.000
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.011	0.989	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.011	0.989	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.011	0.989	0.000
O89.6 Failed or difficult intubation during the puerperium	0.011	0.989	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.011	0.989	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.011	0.989	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.011	0.989	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.011	0.989	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.011	0.989	0.000
O12.2 Gestational oedema with proteinuria	0.011	0.989	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.011	0.989	0.000
O02.1 Missed abortion	0.011	0.989	0.000
O87.2 Haemorrhoids in the puerperium	0.010	0.989	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.010	0.989	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.010	0.990	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.010	0.990	0.000
O12.1 Gestational proteinuria	0.010	0.990	0.000
O02.9 Abnormal product of conception, unspecified	0.010	0.990	0.000
O02.8 Other specified abnormal products of conception	0.010	0.990	0.000
O00.9 Ectopic pregnancy, unspecified	0.010	0.990	0.000
O03.7 Complete or unspecified, complicated by embolism	0.009	0.990	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.009	0.990	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.009	0.990	0.000
O03.2 Incomplete, complicated by embolism	0.009	0.990	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.009	0.990	0.000
R19.5 Other fecal abnormalities	0.010	0.990	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.991	0.009
E23 Hypofunction and other disorders of pituitary gland	0.000	0.991	0.009
O14.9 Preeclampsia, unspecified	0.008	0.991	0.000
O12.0 Gestational oedema	0.008	0.991	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.992	0.008
O80-O84 Delivery	0.008	0.992	0.000
O03.4 Incomplete, without complication	0.008	0.992	0.000
S83.2 Tear of meniscus, current	0.008	0.992	0.000
O97 Death from sequelae of direct obstetric causes	0.008	0.992	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.008	0.992	0.000
O95 Obstetric death of unspecified cause	0.008	0.992	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.007	0.992	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.993	0.007
D12.3 Transverse colon	0.007	0.993	0.000
E29.1 Testicular hypofunction	0.000	0.993	0.007
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.993	0.007
O81 Single delivery by forceps and vacuum extractor	0.007	0.993	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.993	0.007
E23.1 Drug-induced hypopituitarism	0.000	0.993	0.007
E20-E35 Disorders of other endocrine glands	0.000	0.993	0.007
E29 Testicular dysfunction	0.000	0.993	0.007
E23.2 Diabetes insipidus	0.000	0.993	0.007
E28.3 Primary ovarian failure	0.000	0.993	0.007
E24 Cushing's syndrome	0.000	0.994	0.006
E28 Ovarian dysfunction	0.000	0.994	0.006
M06.0 Seronegative rheumatoid arthritis	0.000	0.994	0.006
E27 Other disorders of adrenal gland	0.000	0.994	0.006
E24.9 Cushing's syndrome, unspecified	0.000	0.994	0.006
O84 Multiple delivery	0.006	0.994	0.000
O83 Other assisted single delivery	0.006	0.994	0.000
Z52.4 Kidney donor	0.006	0.994	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O96.9 Death from unspecified obstetric cause	0.006	0.994	0.000
O96.1 Death from indirect obstetric cause	0.006	0.994	0.000
O96.0 Death from direct obstetric cause	0.006	0.994	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.006	0.994	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.006	0.994	0.000
O97.0 Death from sequelae of direct obstetric cause	0.006	0.994	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O81.0 Low forceps delivery	0.006	0.994	0.000
T78.4 Allergy, unspecified	0.006	0.994	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.994	0.006
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.005	0.994	0.000
O81.4 Vacuum extractor delivery	0.005	0.994	0.000
S01.9 Open wound of head, part unspecified	0.000	0.994	0.006
O46.9 Antepartum haemorrhage, unspecified	0.005	0.995	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.995	0.005
E22 Hyperfunction of pituitary gland	0.000	0.995	0.005
O81.5 Delivery by combination of forceps and vacuum extractor	0.005	0.995	0.000
O81.3 Other and unspecified forceps delivery	0.005	0.995	0.000
O81.2 Mid-cavity forceps with rotation	0.005	0.995	0.000
O81.1 Mid-cavity forceps delivery	0.005	0.995	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.995	0.005
E32 Diseases of thymus	0.000	0.995	0.005
E31 Polyglandular dysfunction	0.000	0.995	0.005
E30 Disorders of puberty, not elsewhere classified	0.000	0.995	0.005
E25 Adrenogenital disorders	0.000	0.995	0.005
S02.30 Fracture of orbital floor (closed)	0.005	0.995	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.995	0.005
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.995	0.005
E29.9 Testicular dysfunction, unspecified	0.000	0.995	0.005
E29.8 Other testicular dysfunction	0.000	0.995	0.005
E29.0 Testicular hyperfunction	0.000	0.995	0.005
O20.0 Threatened abortion	0.005	0.995	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.995	0.005
E23.6 Other disorders of pituitary gland	0.000	0.995	0.005
E27.2 Addisonian crisis	0.000	0.995	0.005
E24.8 Other Cushing's syndrome	0.000	0.995	0.005
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.995	0.005
E24.3 Ectopic ACTH syndrome	0.000	0.995	0.005
E24.1 Nelson's syndrome	0.000	0.995	0.005
E24.0 Pituitary-dependent Cushing's disease	0.000	0.995	0.005
E28.9 Ovarian dysfunction, unspecified	0.000	0.995	0.005
E28.8 Other ovarian dysfunction	0.000	0.995	0.005
E28.1 Androgen excess	0.000	0.995	0.005
E28.0 Oestrogen excess	0.000	0.995	0.005
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.995	0.005
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.995	0.005
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.995	0.005
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.995	0.005
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.995	0.005
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.995	0.005
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.995	0.005
E27.5 Adrenomedullary hyperfunction	0.000	0.995	0.005
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.995	0.005
E27.0 Other adrenocortical overactivity	0.000	0.995	0.005
O46 Antepartum haemorrhage, not elsewhere classified	0.005	0.995	0.000
N88.2 Stricture and stenosis of cervix uteri	0.000	0.995	0.005
O83.9 Assisted single delivery, unspecified	0.004	0.995	0.000
O83.8 Other specified assisted single delivery	0.004	0.995	0.000
O83.4 Destructive operation for delivery	0.004	0.995	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.004	0.995	0.000
O83.2 Other manipulation-assisted delivery	0.004	0.995	0.000
O83.1 Other assisted breech delivery	0.004	0.995	0.000
O83.0 Breech extraction	0.004	0.995	0.000
O84.9 Multiple delivery, unspecified	0.004	0.995	0.000
O84.8 Other multiple delivery	0.004	0.995	0.000
O84.2 Multiple delivery, all by Caesarean section	0.004	0.995	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.004	0.995	0.000
O84.0 Multiple delivery, all spontaneous	0.004	0.995	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.995	0.005
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.005	0.995	0.000
E26 Hyperaldosteronism	0.000	0.995	0.004
O03.9 Complete or unspecified, without complication	0.004	0.995	0.000
E20 Hypoparathyroidism	0.000	0.995	0.004
R06.4 Hyperventilation	0.000	0.995	0.005
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.004	0.996	0.000
C22.0 Liver cell carcinoma	0.004	0.996	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.996	0.004
K51.4 Pseudopolyposis of colon	0.000	0.996	0.004
H72.0 Central perforation of tympanic membrane	0.004	0.996	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.996	0.004
K50.1 Crohn's disease of large intestine	0.000	0.996	0.004
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.004	0.996	0.000
O41 Other disorders of amniotic fluid and membranes	0.004	0.996	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.996	0.004
E22.8 Other hyperfunction of pituitary gland	0.000	0.996	0.004
E25.9 Adrenogenital disorder, unspecified	0.000	0.996	0.004
E25.8 Other adrenogenital disorders	0.000	0.996	0.004
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.996	0.004
E30.9 Disorder of puberty, unspecified	0.000	0.996	0.004
E30.8 Other disorders of puberty	0.000	0.996	0.004
E30.1 Precocious puberty	0.000	0.996	0.004
E30.0 Delayed puberty	0.000	0.996	0.004
E31.9 Polyglandular dysfunction, unspecified	0.000	0.996	0.004
E31.8 Other polyglandular dysfunction	0.000	0.996	0.004
E31.1 Polyglandular hyperfunction	0.000	0.996	0.004
E31.0 Autoimmune polyglandular failure	0.000	0.996	0.004
E32.9 Disease of thymus, unspecified	0.000	0.996	0.004
E32.8 Other diseases of thymus	0.000	0.996	0.004
E32.1 Abscess of thymus	0.000	0.996	0.004
E32.0 Persistent hyperplasia of thymus	0.000	0.996	0.004
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.996	0.004
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.996	0.004
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.996	0.004
J93 Pneumothorax	0.000	0.996	0.004
K50 Crohn's disease [regional enteritis]	0.000	0.996	0.004
E34 Other endocrine disorders	0.000	0.996	0.004
E22.0 Acromegaly and pituitary gigantism	0.000	0.996	0.004
O41.0 Oligohydramnios	0.004	0.996	0.000
O46.8 Other antepartum haemorrhage	0.004	0.996	0.000
K50.0 Crohn's disease of small intestine	0.000	0.996	0.004
E22.1 Hyperprolactinaemia	0.000	0.996	0.004
O45 Premature separation of placenta [abruptio placentae]	0.004	0.996	0.000
K50.9 Crohn's disease, unspecified	0.000	0.996	0.004
O46.0 Antepartum haemorrhage with coagulation defect	0.004	0.996	0.000
O44 Placenta praevia	0.004	0.996	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.004	0.996	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.996	0.003
E26.8 Other hyperaldosteronism	0.000	0.996	0.003
E26.1 Secondary hyperaldosteronism	0.000	0.996	0.003
E28.2 Polycystic ovarian syndrome	0.000	0.996	0.003
K62.4 Stenosis of anus and rectum	0.000	0.996	0.004
E20.8 Other hypoparathyroidism	0.000	0.996	0.003
E20.1 Pseudohypoparathyroidism	0.000	0.996	0.003
E20.0 Idiopathic hypoparathyroidism	0.000	0.996	0.003
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.996	0.004
Y83.1 Surgical operation with implant of artificial internal device	0.000	0.996	0.004
R26 Abnormalities of gait and mobility	0.000	0.996	0.003
I46.9 Cardiac arrest, unspecified	0.004	0.996	0.000
C22.1 Intrahepatic bile duct carcinoma	0.003	0.997	0.000
O45.9 Premature separation of placenta, unspecified	0.003	0.997	0.000
S30.1 Contusion of abdominal wall	0.000	0.997	0.003
O41.8 Other specified disorders of amniotic fluid and membranes	0.003	0.997	0.000
O33 Maternal care for known or suspected disproportion	0.003	0.997	0.000
Z31 Procreative management	0.003	0.997	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.003	0.997	0.000
E34.8 Other specified endocrine disorders	0.000	0.997	0.003
K50.8 Other Crohn's disease	0.000	0.997	0.003
O31 Complications specific to multiple gestation	0.003	0.997	0.000
Z31.2 In vitro fertilisation	0.003	0.997	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.003	0.997	0.000
O41.1 Infection of amniotic sac and membranes	0.003	0.997	0.000
R26.3 Immobility	0.000	0.997	0.003
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.997	0.003
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
E34.5 Androgen resistance syndrome	0.000	0.997	0.003
E34.4 Constitutional tall stature	0.000	0.997	0.003
E34.3 Short stature, not elsewhere classified	0.000	0.997	0.003
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.997	0.003
E34.1 Other hypersecretion of intestinal hormones	0.000	0.997	0.003
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.997	0.003
K51 Ulcerative colitis	0.000	0.997	0.003
O44.1 Placenta praevia with haemorrhage	0.003	0.997	0.000
H65.3 Chronic mucoid otitis media	0.003	0.997	0.000
Z31.4 Procreative investigation and testing	0.003	0.997	0.000
J93.0 Spontaneous tension pneumothorax	0.000	0.997	0.003
E26.0 Primary hyperaldosteronism	0.000	0.997	0.003
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.997	0.003
O45.8 Other premature separation of placenta	0.003	0.997	0.000
O45.0 Premature separation of placenta with coagulation defect	0.003	0.997	0.000
C22.9 Liver, unspecified	0.003	0.997	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.997	0.003
J93.1 Other spontaneous pneumothorax	0.000	0.997	0.003
O35 Maternal care for known or suspected foetal abnormality and damage	0.003	0.997	0.000
S02.3 Fracture of orbital floor	0.003	0.997	0.000
C22.7 Other specified carcinomas of liver	0.003	0.997	0.000
C22.4 Other sarcomas of liver	0.003	0.997	0.000
C22.3 Angiosarcoma of liver	0.003	0.997	0.000
C22.2 Hepatoblastoma	0.003	0.997	0.000
N49.2 Inflammatory disorders of scrotum	0.000	0.997	0.003
G50.0 Trigeminal neuralgia	0.003	0.997	0.000
O33.9 Maternal care for disproportion, unspecified	0.003	0.997	0.000
Q10.0 Congenital ptosis	0.003	0.997	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.003	0.997	0.000
O82 Single delivery by Caesarean section	0.003	0.997	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.997	0.002
Z31.9 Procreative management, unspecified	0.003	0.997	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.003	0.997	0.000
R26.1 Paralytic gait	0.000	0.997	0.003
H72 Perforation of tympanic membrane	0.003	0.997	0.000
K51.8 Other ulcerative colitis	0.000	0.997	0.003
S20 Superficial injury of thorax	0.000	0.997	0.003
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.997	0.003
O33.8 Maternal care for disproportion of other origin	0.003	0.997	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.003	0.997	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.003	0.997	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.003	0.997	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.003	0.997	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.003	0.997	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.003	0.997	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.003	0.997	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.003	0.997	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.000	0.997	0.003
O43 Placental disorders	0.003	0.997	0.000
H72.1 Attic perforation of tympanic membrane	0.003	0.997	0.000
Z31.6 General counselling and advice on procreation	0.003	0.997	0.000
Z31.5 Genetic counselling	0.003	0.997	0.000
Z31.3 Other assisted fertilisation methods	0.003	0.997	0.000
Z31.1 Artifical insemination	0.003	0.997	0.000
H65 Nonsuppurative otitis media	0.003	0.997	0.000
S52.80 Fracture of other parts of forearm (closed)	0.003	0.997	0.000
Q21.0 Ventricular septal defect	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.997	0.003
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.003	0.997	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.003	0.997	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.997	0.003
O31.8 Other complications specific to multiple gestation	0.002	0.997	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.002	0.997	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.002	0.997	0.000
O31.0 Papyraceous foetus	0.002	0.997	0.000
H65-H75 Diseases of middle ear and mastoid	0.003	0.997	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.002
K51.5 Mucosal proctocolitis	0.000	0.997	0.003
C21.0 Anus, unspecified	0.003	0.997	0.000
L40.9 Psoriasis, unspecified	0.003	0.997	0.000
Z31.8 Other procreative management	0.002	0.997	0.000
E34.0 Carcinoid syndrome	0.000	0.997	0.002
Z89.4 Acquired absence of foot and ankle	0.000	0.997	0.003
Q27 Other congenital malformations of peripheral vascular system	0.002	0.997	0.000
O32.0 Maternal care for unstable lie	0.002	0.997	0.000
C21 Malignant neoplasm of anus and anal canal	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations