TreeWAS – Variant ID: rs17033506

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
M20-M25 Other joint disorders	0.997	0.003
M50-M54 Other dorsopathies	0.995	0.005
M54 Dorsalgia	0.992	0.008
Chapter IV Endocrine, nutritional and metabolic diseases	0.990	0.010
Chapter XIV Diseases of the genitourinary system	0.989	0.011
M54.5 Low back pain	0.987	0.013
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.984	0.016
M23 Internal derangement of knee	0.983	0.017
E70-E90 Metabolic disorders	0.983	0.017
E86 Volume depletion	0.980	0.020
M15-M19 Arthrosis	0.974	0.026
M05-M14 Inflammatory polyarthropathies	0.973	0.027
N80-N98 Noninflammatory disorders of female genital tract	0.951	0.049
M54.59 Low back pain (Site unspecified)	0.950	0.050
M13 Other arthritis	0.947	0.053
M23.2 Derangement of meniscus due to old tear or injury	0.942	0.058
M13.9 Arthritis, unspecified	0.929	0.071
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.929	0.071
M17 Gonarthrosis [arthrosis of knee]	0.926	0.074
M25 Other joint disorders, not elsewhere classified	0.919	0.081
Chapter IX Diseases of the circulatory system	0.916	0.084
M23.3 Other meniscus derangements	0.916	0.084
M54.56 Low back pain (Lumbar region)	0.908	0.092
Chapter V Mental and behavioural disorders	0.903	0.097
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.889	0.111
N20-N23 Urolithiasis	0.886	0.114
N85 Other noninflammatory disorders of uterus, except cervix	0.884	0.116
N10-N16 Renal tubulo-interstitial diseases	0.881	0.119
Chapter VIII Diseases of the ear and mastoid process	0.879	0.121
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.877	0.123
I84 Haemorrhoids	0.873	0.127
N93 Other abnormal uterine and vaginal bleeding	0.859	0.141
I84.9 Unspecified haemorrhoids without complication	0.855	0.145
M17.9 Gonarthrosis, unspecified	0.851	0.149
T81 Complications of procedures, not elsewhere classified	0.851	0.149
E00-E07 Disorders of thyroid gland	0.849	0.151
M54.9 Dorsalgia, unspecified	0.848	0.152
M65-M68 Disorders of synovium and tendon	0.847	0.153
N80 Endometriosis	0.839	0.161
T36-T50 Poisoning by drugs, medicaments and biological substances	0.839	0.161
M13.99 Arthritis, unspecified (Site unspecified)	0.836	0.163
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.827	0.173
M54.57 Low back pain (Lumbosacral region)	0.827	0.173
I30-I52 Other forms of heart disease	0.820	0.180
S80-S89 Injuries to the knee and lower leg	0.818	0.182
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.818	0.182
I84.2 Internal haemorrhoids without complication	0.817	0.183
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.812	0.188
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.812	0.188
M25.5 Pain in joint	0.810	0.190
M13.96 Arthritis, unspecified (Lower leg)	0.810	0.190
T81.4 Infection following a procedure, not elsewhere classified	0.807	0.193
Chapter XV Pregnancy, childbirth and the puerperium	0.804	0.196
M70-M79 Other soft tissue disorders	0.802	0.198
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.801	0.199
M16 Coxarthrosis [arthrosis of hip]	0.797	0.203
N00-N08 Glomerular diseases	0.797	0.203
E83 Disorders of mineral metabolism	0.795	0.205
M18 Arthrosis of first carpometacarpal joint	0.794	0.206
S60-S69 Injuries to the wrist and hand	0.793	0.207
M13.94 Arthritis, unspecified (Hand)	0.793	0.207
N17-N19 Renal failure	0.790	0.210
N86 Erosion and ectropion of cervix uteri	0.789	0.211
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.789	0.211
M17.1 Other primary gonarthrosis	0.785	0.215
N20 Calculus of kidney and ureter	0.785	0.215
M25.7 Osteophyte	0.783	0.217
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.780	0.220
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.780	0.220
I70-I79 Diseases of arteries, arterioles and capillaries	0.777	0.223
M35 Other systemic involvement of connective tissue	0.773	0.227
M22 Disorders of patella	0.771	0.228
M86-M90 Other osteopathies	0.771	0.229
N80.0 Endometriosis of uterus	0.770	0.230
S00-S09 Injuries to the head	0.767	0.233
Chapter VII Diseases of the eye and adnexa	0.766	0.234
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.765	0.235
M50 Cervical disk disorders	0.758	0.242
T81.8 Other complications of procedures, not elsewhere classified	0.757	0.243
M54.2 Cervicalgia	0.753	0.247
I35 Nonrheumatic aortic valve disorders	0.749	0.251
E20-E35 Disorders of other endocrine glands	0.748	0.252
N85.8 Other specified noninflammatory disorders of uterus	0.747	0.253
N23 Unspecified renal colic	0.747	0.253
T79-T79 Certain early complications of trauma	0.744	0.256
H65-H75 Diseases of middle ear and mastoid	0.744	0.256
N13 Obstructive and reflux uropathy	0.744	0.256
E04 Other non-toxic goitre	0.742	0.258
M40-M43 Deforming dorsopathies	0.742	0.258
M06 Other rheumatoid arthritis	0.742	0.258
N85.2 Hypertrophy of uterus	0.741	0.259
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.740	0.260
M13.90 Arthritis, unspecified (Multiple sites)	0.739	0.261
N93.8 Other specified abnormal uterine and vaginal bleeding	0.738	0.262
N90 Other noninflammatory disorders of vulva and perineum	0.732	0.268
F00-F09 Organic, including symptomatic, mental disorders	0.730	0.270
N85.0 Endometrial glandular hyperplasia	0.730	0.270
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.729	0.271
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.728	0.272
T66-T78 Other and unspecified effects of external causes	0.727	0.273
M25.8 Other specified joint disorders	0.726	0.274
I85 Oesophageal varices	0.726	0.274
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.726	0.274
M54.99 Dorsalgia, unspecified (Site unspecified)	0.725	0.275
M23.8 Other internal derangements of knee	0.724	0.276
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.724	0.276
M11 Other crystal arthropathies	0.723	0.277
S90-S99 Injuries to the ankle and foot	0.722	0.278
N70-N77 Inflammatory diseases of female pelvic organs	0.721	0.279
M65 Synovitis and tenosynovitis	0.717	0.282
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.717	0.283
M91-M94 Chondropathies	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
N25-N29 Other disorders of kidney and ureter	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.714	0.285
M34 Systemic sclerosis	0.714	0.285
M33 Dermatopolymyositis	0.714	0.285
M32 Systemic lupus erythematosus	0.714	0.285
M31 Other necrotising vasculopathies	0.714	0.285
M30 Polyarteritis nodosa and related conditions	0.714	0.285
M21 Other acquired deformities of limbs	0.714	0.285
I95-I99 Other and unspecified disorders of the circulatory system	0.714	0.286
M53 Other dorsopathies, not elsewhere classified	0.713	0.287
M19 Other arthrosis	0.713	0.287
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.712	0.288
H80-H83 Diseases of inner ear	0.711	0.289
M54.8 Other dorsalgia	0.711	0.289
M54.6 Pain in thoracic spine	0.711	0.289
M54.4 Lumbago with sciatica	0.711	0.289
M54.3 Sciatica	0.711	0.289
M54.1 Radiculopathy	0.711	0.289
M54.0 Panniculitis affecting regions of neck and back	0.711	0.289
M79 Other soft tissue disorders, not elsewhere classified	0.711	0.289
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.711	0.289
E05 Thyrotoxicosis [hyperthyroidism]	0.710	0.289
N20.0 Calculus of kidney	0.710	0.290
H60-H62 Diseases of external ear	0.710	0.290
E40-E46 Malnutrition	0.709	0.290
M24 Other specific joint derangements	0.708	0.292
M54.55 Low back pain (Thoracolumbar region)	0.708	0.292
M54.54 Low back pain-Thoracic	0.708	0.292
M54.53 Low back pain-Cervicothoracic	0.708	0.292
M54.52 Low back pain-Cervical	0.708	0.292
M54.51 Low back pain-Occipit-atl-axl	0.708	0.292
M54.50 Low back pain (Multiple sites in spine)	0.708	0.292
M20 Acquired deformities of fingers and toes	0.708	0.292
T85 Complications of other internal prosthetic devices, implants and grafts	0.706	0.294
T33-T35 Frostbite	0.705	0.295
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.705	0.295
T26-T28 Burns and corrosions confined to eye and internal organs	0.705	0.295
T20-T25 Burns and corrosions of external body surface, specified by site	0.705	0.295
T15-T19 Effects of foreign body entering through natural orifice	0.705	0.295
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.705	0.295
T00-T07 Injuries involving multiple body regions	0.705	0.295
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.705	0.295
S20-S29 Injuries to the thorax	0.705	0.295
S10-S19 Injuries to the neck	0.705	0.295
M23.9 Internal derangement of knee, unspecified	0.705	0.295
M23.6 Other spontaneous disruption of ligament(s) of knee	0.705	0.295
M23.5 Chronic instability of knee	0.705	0.295
M23.4 Loose body in knee	0.705	0.295
M23.1 Discoid meniscus (congenital)	0.705	0.295
M23.0 Cystic meniscus	0.705	0.295
E88 Other metabolic disorders	0.705	0.295
E85 Amyloidosis	0.705	0.295
E84 Cystic fibrosis	0.705	0.295
E80 Disorders of porphyrin and bilirubin metabolism	0.705	0.295
E79 Disorders of purine and pyrimidine metabolism	0.705	0.295
E77 Disorders of glycoprotein metabolism	0.705	0.295
E76 Disorders of glycosaminoglycan metabolism	0.705	0.295
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.705	0.295
E74 Other disorders of carbohydrate metabolism	0.705	0.295
E73 Lactose intolerance	0.705	0.295
E72 Other disorders of amino-acid metabolism	0.705	0.295
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.705	0.295
E70 Disorders of aromatic amino-acid metabolism	0.705	0.295
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.705	0.295
M10 Gout	0.703	0.297
N81 Female genital prolapse	0.702	0.298
N95 Menopausal and other perimenopausal disorders	0.702	0.298
M17.0 Primary gonarthrosis, bilateral	0.700	0.300
M15 Polyarthrosis	0.698	0.302
M14 Arthropathies in other diseases classified elsewhere	0.698	0.302
M12 Other specific arthropathies	0.698	0.302
M09 Juvenile arthritis in diseases classified elsewhere	0.698	0.302
M08 Juvenile arthritis	0.698	0.302
M07 Psoriatic and enteropathic arthropathies	0.698	0.302
M05 Seropositive rheumatoid arthritis	0.698	0.302
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.693	0.307
I31 Other diseases of pericardium	0.692	0.308
M80-M85 Disorders of bone density and structure	0.691	0.309
F10 Mental and behavioural disorders due to use of alcohol	0.690	0.310
N98 Complications associated with artificial fertilisation	0.682	0.318
N91 Absent, scanty and rare menstruation	0.682	0.318
N82 Fistulae involving female genital tract	0.682	0.318
N96 Habitual aborter	0.682	0.318
M25.55 Pain in joint (Pelvic region and thigh)	0.682	0.318
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.681	0.319
M13.8 Other specified arthritis	0.679	0.321
M13.1 Monoarthritis, not elsewhere classified	0.679	0.321
M13.0 Polyarthritis, unspecified	0.679	0.321
S70-S79 Injuries to the hip and thigh	0.677	0.323
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.676	0.324
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.675	0.325
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.675	0.325
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.675	0.325
M25.56 Pain in joint (Lower leg)	0.675	0.325
I84.7 Unspecified thrombosed haemorrhoids	0.675	0.325
N99-N99 Other disorders of the genitourinary system	0.673	0.327
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.672	0.328
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.671	0.329
M16.1 Other primary coxarthrosis	0.671	0.329
E89.0 Postprocedural hypothyroidism	0.670	0.330
O60-O75 Complications of labour and delivery	0.669	0.331
N03 Chronic nephritic syndrome	0.668	0.332
I71 Aortic aneurysm and dissection	0.667	0.333
E87 Other disorders of fluid, electrolyte and acid-base balance	0.667	0.333
M25.71 Osteophyte (Shoulder region)	0.667	0.333
M13.98 Arthritis, unspecified (Other)	0.666	0.334
M13.93 Arthritis, unspecified (Forearm)	0.666	0.334
M13.92 Arthritis, unspecified (Upper arm)	0.666	0.334
M13.91 Arthritis, unspecified (Shoulder region)	0.666	0.334
I84.6 Residual haemorrhoidal skin tags	0.666	0.334
T88 Other complications of surgical and medical care, not elsewhere classified	0.666	0.334
T87 Complications peculiar to reattachment and amputation	0.666	0.334
T86 Failure and rejection of transplanted organs and tissues	0.666	0.334
T80 Complications following infusion, transfusion and therapeutic injection	0.666	0.334
S82 Fracture of lower leg, including ankle	0.666	0.334
Chapter VI Diseases of the nervous system	0.665	0.335
M17.5 Other secondary gonarthrosis	0.664	0.336
M17.4 Other secondary gonarthrosis, bilateral	0.664	0.336
M17.3 Other posttraumatic gonarthrosis	0.664	0.336
M17.2 Posttraumatic gonarthrosis, bilateral	0.664	0.336
N94.1 Dyspareunia	0.663	0.337
N80.1 Endometriosis of ovary	0.662	0.338
Chapter XI Diseases of the digestive system	0.660	0.340
M25.50 Pain in joint (Multiple sites)	0.659	0.341
M25.9 Joint disorder, unspecified	0.659	0.341
M25.6 Stiffness of joint, not elsewhere classified	0.659	0.341
M25.3 Other instability of joint	0.659	0.341
M25.2 Flail joint	0.659	0.341
M25.1 Fistula of joint	0.659	0.341
M25.0 Haemarthrosis	0.659	0.341
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.658	0.341
Chapter XII Diseases of the skin and subcutaneous tissue	0.658	0.342
S40-S49 Injuries to the shoulder and upper arm	0.657	0.343
I00-I02 Acute rheumatic fever	0.657	0.343
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.656	0.343
M23.37 Other meniscus derangements-Capsular lig	0.656	0.343
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.656	0.343
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.656	0.343
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.656	0.343
E10-E14 Diabetes mellitus	0.656	0.344
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.654	0.346
N40-N51 Diseases of male genital organs	0.653	0.347
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.653	0.347
S00 Superficial injury of head	0.653	0.347
H53-H54 Visual disturbances and blindness	0.652	0.348
F30-F39 Mood [affective] disorders	0.651	0.349
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.651	0.349
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.651	0.349
T84.0 Mechanical complication of internal joint prosthesis	0.650	0.349
I51 Complications and ill-defined descriptions of heart disease	0.650	0.350
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.650	0.350
M25.76 Osteophyte (Lower leg)	0.650	0.350
Chapter I Certain infectious and parasitic diseases	0.649	0.351
M54.96 Dorsalgia, unspecified (Lumbar region)	0.649	0.351
M23.30 Other meniscus derangements (Multiple sites)	0.648	0.352
F99-F99 Unspecified mental disorder	0.647	0.353
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.647	0.353
F80-F89 Disorders of psychological development	0.647	0.353
F70-F79 Mental retardation	0.647	0.353
F60-F69 Disorders of adult personality and behaviour	0.647	0.353
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.647	0.353
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.647	0.353
M67 Other disorders of synovium and tendon	0.643	0.356
E83.1 Disorders of iron metabolism	0.643	0.357
M13.97 Arthritis, unspecified (Ankle and foot)	0.642	0.358
S50-S59 Injuries to the elbow and forearm	0.642	0.358
N93.0 Postcoital and contact bleeding	0.642	0.358
E50-E64 Other nutritional deficiencies	0.641	0.359
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.640	0.360
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.640	0.360
F40-F48 Neurotic, stress-related and somatoform disorders	0.639	0.361
I35.1 Aortic (valve) insufficiency	0.639	0.361
M20.5 Other deformities of toe(s) (acquired)	0.639	0.361
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.638	0.361
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.637	0.362
I88 Nonspecific lymphadenitis	0.637	0.362
I87 Other disorders of veins	0.637	0.362
I86 Varicose veins of other sites	0.637	0.362
I82 Other venous embolism and thrombosis	0.637	0.362
I81 Portal vein thrombosis	0.637	0.362
N19 Unspecified renal failure	0.636	0.364
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.636	0.364
N22 Calculus of urinary tract in diseases classified elsewhere	0.635	0.365
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.635	0.365
N18 Chronic renal failure	0.635	0.365
N85.9 Noninflammatory disorder of uterus, unspecified	0.634	0.366
N85.7 Haematometra	0.634	0.366
N85.6 Intra-uterine synechiae	0.634	0.366
N85.5 Inversion of uterus	0.634	0.366
N85.4 Malposition of uterus	0.634	0.366
N85.3 Subinvolution of uterus	0.634	0.366
N85.1 Endometrial adenomatous hyperplasia	0.634	0.366
I84.4 External haemorrhoids with other complications	0.632	0.368
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.631	0.368
N15 Other renal tubulo-interstitial diseases	0.631	0.368
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.631	0.368
N11 Chronic tubulo-interstitial nephritis	0.631	0.368
N10 Acute tubulo-interstitial nephritis	0.631	0.368
N60-N64 Disorders of breast	0.630	0.369
T81.3 Disruption of operation wound, not elsewhere classified	0.630	0.370
I05-I09 Chronic rheumatic heart diseases	0.629	0.370
H25-H28 Disorders of lens	0.628	0.372
I84.3 External thrombosed haemorrhoids	0.626	0.374
I84.0 Internal thrombosed haemorrhoids	0.626	0.374
I35.2 Aortic (valve) stenosis with insufficiency	0.625	0.375
I78 Diseases of capillaries	0.624	0.376
S66 Injury of muscle and tendon at wrist and hand level	0.624	0.376
M35.3 Polymyalgia rheumatica	0.622	0.378
I80 Phlebitis and thrombophlebitis	0.622	0.378
I49 Other cardiac arrhythmias	0.618	0.382
N20.2 Calculus of kidney with calculus of ureter	0.614	0.386
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.613	0.387
M25.53 Pain in joint (Forearm)	0.613	0.387
N13.4 Hydroureter	0.613	0.387
M65.9 Synovitis and tenosynovitis, unspecified	0.612	0.388
I46 Cardiac arrest	0.611	0.389
I47 Paroxysmal tachycardia	0.610	0.390
T81.9 Unspecified complication of procedure	0.610	0.390
T81.7 Vascular complications following a procedure, not elsewhere classified	0.610	0.390
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.610	0.390
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.610	0.390
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.610	0.390
I85.9 Oesophageal varices without bleeding	0.609	0.391
E07 Other disorders of thyroid	0.609	0.391
E06 Thyroiditis	0.609	0.391
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.609	0.391
E00 Congenital iodine-deficiency syndrome	0.609	0.391
E02 Subclinical iodine-deficiency hypothyroidism	0.609	0.391
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.608	0.392
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.608	0.392
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.608	0.392
M54.94 Dorsalgia, unspecified (Thoracic region)	0.608	0.392
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.608	0.392
M54.92 Dorsalgia, unspecified (Cervical region)	0.608	0.392
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.608	0.392
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.608	0.392
M79.6 Pain in limb	0.608	0.392
M22.2 Patellofemoral disorders	0.608	0.392
M16.0 Primary coxarthrosis, bilateral	0.607	0.393
H81 Disorders of vestibular function	0.607	0.393
M89 Other disorders of bone	0.607	0.393
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.607	0.393
M66 Spontaneous rupture of synovium and tendon	0.607	0.393
M25.75 Osteophyte (Pelvic region and thigh)	0.607	0.393
E05.9 Thyrotoxicosis, unspecified	0.607	0.393
E04.9 Non-toxic goitre, unspecified	0.607	0.393
F17 Mental and behavioural disorders due to use of tobacco	0.606	0.394
S68 Traumatic amputation of wrist and hand	0.606	0.394
M51 Other intervertebral disk disorders	0.606	0.394
H65 Nonsuppurative otitis media	0.606	0.394
O00-O08 Pregnancy with abortive outcome	0.605	0.395
S62 Fracture at wrist and hand level	0.605	0.395
N80.8 Other endometriosis	0.602	0.398
N80.6 Endometriosis in cutaneous scar	0.602	0.398
N80.5 Endometriosis of intestine	0.602	0.398
N80.4 Endometriosis of rectovaginal septum and vagina	0.602	0.398
N80.2 Endometriosis of Fallopian tube	0.602	0.398
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.601	0.398
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.601	0.398
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.601	0.398
T46 Poisoning by agents primarily affecting the cardiovascular system	0.601	0.398
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.601	0.398
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.601	0.398
T41 Poisoning by anaesthetics and therapeutic gases	0.601	0.398
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.601	0.398
T36 Poisoning by systemic antibiotics	0.601	0.398
I31.3 Pericardial effusion (noninflammatory)	0.601	0.399
Chapter XX External causes of morbidity and mortality	0.601	0.399
E83.5 Disorders of calcium metabolism	0.600	0.400
Chapter XXI Factors influencing health status and contact with health services	0.600	0.400
N88 Other noninflammatory disorders of cervix uteri	0.598	0.402
M18.1 Other primary arthrosis of first carpometacarpal joint	0.598	0.402
F03 Unspecified dementia	0.597	0.403
H72 Perforation of tympanic membrane	0.597	0.403
Q20-Q28 Congenital malformations of the circulatory system	0.597	0.403
N83.2 Other and unspecified ovarian cysts	0.594	0.406
M50.2 Other cervical disk displacement	0.593	0.407
F10.3 Withdrawal state	0.592	0.408
K65-K67 Diseases of peritoneum	0.591	0.409
E04.2 Non-toxic multinodular goitre	0.589	0.411
N97 Female infertility	0.588	0.411
N87 Dysplasia of cervix uteri	0.588	0.411
H61 Other disorders of external ear	0.588	0.412
N80.9 Endometriosis, unspecified	0.588	0.412
M25.86 Other specified joint disorders (Lower leg)	0.588	0.412
I52 Other heart disorders in diseases classified elsewhere	0.588	0.412
I48 Atrial fibrillation and flutter	0.588	0.412
I43 Cardiomyopathy in diseases classified elsewhere	0.588	0.412
I41 Myocarditis in diseases classified elsewhere	0.588	0.412
I40 Acute myocarditis	0.588	0.412
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.588	0.412
I37 Pulmonary valve disorders	0.588	0.412
I36 Nonrheumatic tricuspid valve disorders	0.588	0.412
I33 Acute and subacute endocarditis	0.588	0.412
I32 Pericarditis in diseases classified elsewhere	0.588	0.412
I30 Acute pericarditis	0.588	0.412
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.588	0.412
F10.1 Harmful use	0.587	0.413
S89 Other and unspecified injuries of lower leg	0.587	0.413
S88 Traumatic amputation of lower leg	0.587	0.413
S87 Crushing injury of lower leg	0.587	0.413
S86 Injury of muscle and tendon at lower leg level	0.587	0.413
S85 Injury of blood vessels at lower leg level	0.587	0.413
S84 Injury of nerves at lower leg level	0.587	0.413
S81 Open wound of lower leg	0.587	0.413
S80 Superficial injury of lower leg	0.587	0.413
E27 Other disorders of adrenal gland	0.586	0.414
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.585	0.415
N72 Inflammatory disease of cervix uteri	0.585	0.415
M54.22 Cervicalgia (Cervical region)	0.582	0.418
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.582	0.418
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.582	0.418
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.582	0.418
T84.3 Mechanical complication of other bone devices, implants and grafts	0.582	0.418
T84.2 Mechanical complication of internal fixation device of other bones	0.582	0.418
M25.59 Pain in joint (Site unspecified)	0.581	0.419
M25.58 Pain in joint (Other)	0.581	0.419
M25.54 Pain in joint (Hand)	0.581	0.419
M25.52 Pain in joint (Upper arm)	0.581	0.419
E04.1 Non-toxic single thyroid nodule	0.580	0.420
I35.0 Aortic (valve) stenosis	0.580	0.420
M79.0 Rheumatism, unspecified	0.579	0.421
I51.7 Cardiomegaly	0.579	0.421
M25.4 Effusion of joint	0.577	0.422
I77 Other disorders of arteries and arterioles	0.577	0.422
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.577	0.423
H50 Other strabismus	0.577	0.423
O85-O92 Complications predominantly related to the puerperium	0.576	0.424
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.576	0.424
M06.9 Rheumatoid arthritis, unspecified	0.576	0.424
M77 Other enthesopathies	0.575	0.425
M76 Enthesopathies of lower limb, excluding foot	0.575	0.425
M73 Soft tissue disorders in diseases classified elsewhere	0.575	0.425
M71 Other bursopathies	0.575	0.425
M70 Soft tissue disorders related to use, overuse and pressure	0.575	0.425
N03.9 Unspecified	0.575	0.425
I38 Endocarditis, valve unspecified	0.575	0.425
M72 Fibroblastic disorders	0.574	0.426
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.574	0.426
E89.8 Other postprocedural endocrine and metabolic disorders	0.574	0.426
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.574	0.426
E89.5 Postprocedural testicular hypofunction	0.574	0.426
E89.4 Postprocedural ovarian failure	0.574	0.426
E89.3 Postprocedural hypopituitarism	0.574	0.426
E89.2 Postprocedural hypoparathyroidism	0.574	0.426
E89.1 Postprocedural hypoinsulinaemia	0.574	0.426
I34 Nonrheumatic mitral valve disorders	0.573	0.427
O80-O84 Delivery	0.573	0.427
M41 Scoliosis	0.572	0.427
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.572	0.428
T79 Certain early complications of trauma, not elsewhere classified	0.572	0.428
M16.7 Other secondary coxarthrosis	0.572	0.428
M16.6 Other secondary coxarthrosis, bilateral	0.572	0.428
M16.5 Other posttraumatic coxarthrosis	0.572	0.428
M16.4 Posttraumatic coxarthrosis, bilateral	0.572	0.428
M16.3 Other dysplastic coxarthrosis	0.572	0.428
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.572	0.428
N08 Glomerular disorders in diseases classified elsewhere	0.571	0.429
N07 Hereditary nephropathy, not elsewhere classified	0.571	0.429
N06 Isolated proteinuria with specified morphological lesion	0.571	0.429
N05 Unspecified nephritic syndrome	0.571	0.429
N04 Nephrotic syndrome	0.571	0.429
N01 Rapidly progressive nephritic syndrome	0.571	0.429
N00 Acute nephritic syndrome	0.571	0.429
N81.6 Rectocele	0.570	0.430
I95 Hypotension	0.570	0.430
E83.9 Disorder of mineral metabolism, unspecified	0.570	0.430
E83.8 Other disorders of mineral metabolism	0.570	0.430
E83.3 Disorders of phosphorus metabolism	0.570	0.430
E83.2 Disorders of zinc metabolism	0.570	0.430
E83.0 Disorders of copper metabolism	0.570	0.430
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.569	0.430
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.569	0.430
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.569	0.430
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.569	0.430
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.569	0.430
I84.5 External haemorrhoids without complication	0.569	0.431
S69 Other and unspecified injuries of wrist and hand	0.569	0.431
S67 Crushing injury of wrist and hand	0.569	0.431
S65 Injury of blood vessels at wrist and hand level	0.569	0.431
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.569	0.431
S60 Superficial injury of wrist and hand	0.569	0.431

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations