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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17040357
log Bayes Factor = 13.7026
Chromosome 12   position 108,665,316  (GRCh37) Explore rs17040357 on Ensembl!
Variant rs17040357 is part of Cluster X0232

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.997 0.003 0.000
Chapter II Neoplasms
0.996 0.004 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.995 0.005 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.994 0.006 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.992 0.008 0.000
D70 Agranulocytosis
0.990 0.010 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.990 0.010 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.983 0.017 0.000
J40-J47 Chronic lower respiratory diseases
0.978 0.022 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.973 0.027 0.000
J44 Other chronic obstructive pulmonary disease
0.973 0.027 0.000
Chapter I Certain infectious and parasitic diseases
0.965 0.035 0.000
C77.2 Intra-abdominal lymph nodes
0.964 0.036 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.963 0.037 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.962 0.038 0.000
Chapter V Mental and behavioural disorders
0.962 0.038 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.962 0.038 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.957 0.043 0.000
E87.2 Acidosis
0.953 0.047 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.950 0.050 0.000
C77.3 Axillary and upper limb lymph nodes
0.947 0.053 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.931 0.069 0.000
J95-J99 Other diseases of the respiratory system
0.931 0.069 0.000
E10-E14 Diabetes mellitus
0.931 0.069 0.000
A30-A49 Other bacterial diseases
0.928 0.072 0.000
Chapter VI Diseases of the nervous system
0.927 0.073 0.000
E86 Volume depletion
0.926 0.074 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.924 0.076 0.000
Chapter VIII Diseases of the ear and mastoid process
0.919 0.081 0.000
Chapter XIV Diseases of the genitourinary system
0.916 0.084 0.000
J00-J06 Acute upper respiratory infections
0.915 0.085 0.000
C77.5 Intrapelvic lymph nodes
0.914 0.086 0.000
E20-E35 Disorders of other endocrine glands
0.913 0.087 0.000
N30-N39 Other diseases of urinary system
0.910 0.090 0.000
J09-J18 Influenza and pneumonia
0.904 0.096 0.000
A41 Other septicaemia
0.902 0.098 0.000
G20-G26 Extrapyramidal and movement disorders
0.902 0.098 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.902 0.098 0.000
Y43 Primarily systemic agents
0.901 0.099 0.000
J20-J22 Other acute lower respiratory infections
0.899 0.101 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.886 0.114 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.886 0.114 0.000
F41 Other anxiety disorders
0.883 0.117 0.000
E83 Disorders of mineral metabolism
0.879 0.121 0.000
D73 Diseases of spleen
0.877 0.123 0.000
E10 Insulin-dependent diabetes mellitus
0.873 0.127 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.872 0.128 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.871 0.129 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.869 0.131 0.000
G25 Other extrapyramidal and movement disorders
0.868 0.132 0.000
N32 Other disorders of bladder
0.866 0.134 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.865 0.135 0.000
J98 Other respiratory disorders
0.863 0.137 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.861 0.139 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.860 0.140 0.000
N35 Urethral stricture
0.857 0.143 0.000
N10-N16 Renal tubulo-interstitial diseases
0.851 0.149 0.000
Y43.3 Other antineoplastic drugs
0.850 0.150 0.000
Chapter IX Diseases of the circulatory system
0.844 0.156 0.000
I60-I69 Cerebrovascular diseases
0.841 0.159 0.000
D80-D89 Certain disorders involving the immune mechanism
0.836 0.164 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.834 0.166 0.000
C90.0 Multiple myeloma
0.831 0.169 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.831 0.169 0.000
E87.7 Fluid overload
0.830 0.170 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.829 0.171 0.000
J22 Unspecified acute lower respiratory infection
0.826 0.174 0.000
B95-B98 Bacterial, viral and other infectious agents
0.825 0.175 0.000
N35.9 Urethral stricture, unspecified
0.819 0.181 0.000
I67 Other cerebrovascular diseases
0.818 0.182 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.817 0.182 0.000
A41.8 Other specified septicaemia
0.813 0.187 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.809 0.191 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.808 0.192 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.808 0.192 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.807 0.193 0.000
Y52 Agents primarily affecting the cardiovascular system
0.807 0.193 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.805 0.195 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.804 0.196 0.000
A41.9 Septicaemia, unspecified
0.804 0.196 0.000
J18 Pneumonia, organism unspecified
0.803 0.197 0.000
F41.9 Anxiety disorder, unspecified
0.802 0.198 0.000
I67.9 Cerebrovascular disease, unspecified
0.801 0.199 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.801 0.199 0.000
J98.1 Pulmonary collapse
0.800 0.200 0.000
G30-G32 Other degenerative diseases of the nervous system
0.799 0.201 0.000
L89 Decubitus ulcer
0.799 0.201 0.000
J90-J94 Other diseases of pleura
0.796 0.204 0.000
D73.0 Hyposplenism
0.792 0.208 0.000
L82 Seborrhoeic keratosis
0.790 0.210 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.789 0.211 0.000
L40-L45 Papulosquamous disorders
0.788 0.212 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.787 0.213 0.000
N32.9 Bladder disorder, unspecified
0.787 0.213 0.000
N32.0 Bladder-neck obstruction
0.787 0.213 0.000
T66-T78 Other and unspecified effects of external causes
0.785 0.215 0.000
J00 Acute nasopharyngitis [common cold]
0.784 0.216 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.784 0.216 0.000
E11 Non-insulin-dependent diabetes mellitus
0.783 0.217 0.000
T18 Foreign body in alimentary tract
0.783 0.217 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.783 0.217 0.000
C77.4 Inguinal and lower limb lymph nodes
0.780 0.220 0.000
J03 Acute tonsillitis
0.780 0.220 0.000
I69 Sequelae of cerebrovascular disease
0.779 0.221 0.000
S70-S79 Injuries to the hip and thigh
0.777 0.223 0.000
H65-H75 Diseases of middle ear and mastoid
0.777 0.223 0.000
W00-W19 Falls
0.776 0.224 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.775 0.225 0.000
Y57 Other and unspecified drugs and medicaments
0.774 0.226 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.773 0.227 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.773 0.227 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.772 0.228 0.000
E10.9 Without complications
0.769 0.231 0.000
J42 Unspecified chronic bronchitis
0.768 0.232 0.000
E83.5 Disorders of calcium metabolism
0.767 0.233 0.000
S90-S99 Injuries to the ankle and foot
0.764 0.236 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.763 0.237 0.000
N39 Other disorders of urinary system
0.763 0.237 0.000
D75 Other diseases of blood and blood-forming organs
0.759 0.241 0.000
D00-D09 In situ neoplasms
0.758 0.242 0.000
E88 Other metabolic disorders
0.756 0.244 0.000
D60-D64 Aplastic and other anaemias
0.756 0.244 0.000
G20 Parkinson's disease
0.754 0.246 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.754 0.246 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.753 0.246 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.752 0.248 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.751 0.249 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.751 0.249 0.000
D50-D53 Nutritional anaemias
0.749 0.251 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.748 0.252 0.000
N32.3 Diverticulum of bladder
0.747 0.253 0.000
O60-O75 Complications of labour and delivery
0.747 0.253 0.000
C78.0 Secondary malignant neoplasm of lung
0.746 0.254 0.000
G25.0 Essential tremor
0.746 0.254 0.000
R50-R69 General symptoms and signs
0.744 0.256 0.000
S20-S29 Injuries to the thorax
0.744 0.256 0.000
E87.6 Hypokalaemia
0.744 0.256 0.000
C92 Myeloid leukaemia
0.743 0.257 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.743 0.257 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.742 0.258 0.000
L20-L30 Dermatitis and eczema
0.741 0.259 0.000
L57.0 Actinic keratosis
0.740 0.260 0.000
H90-H95 Other disorders of ear
0.740 0.260 0.000
T82.1 Mechanical complication of cardiac electronic device
0.740 0.260 0.000
J02 Acute pharyngitis
0.739 0.261 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.738 0.261 0.000
N13 Obstructive and reflux uropathy
0.737 0.263 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.737 0.263 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.735 0.265 0.000
F30-F39 Mood [affective] disorders
0.734 0.266 0.000
C51-C58 Malignant neoplasms of female genital organs
0.733 0.266 0.000
Chapter XXI Factors influencing health status and contact with health services
0.733 0.267 0.000
C81 Hodgkin's disease
0.731 0.269 0.000
N00-N08 Glomerular diseases
0.730 0.270 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.729 0.271 0.000
Y84.8 Other medical procedures
0.728 0.272 0.000
H60-H62 Diseases of external ear
0.727 0.273 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.726 0.273 0.000
J40 Bronchitis, not specified as acute or chronic
0.726 0.274 0.000
F41.1 Generalised anxiety disorder
0.725 0.275 0.000
Y43.4 Immunosuppressive agents
0.724 0.276 0.000
W20-W49 Exposure to inanimate mechanical forces
0.722 0.278 0.000
F43 Reaction to severe stress, and adjustment disorders
0.722 0.278 0.000
T18.1 Foreign body in oesophagus
0.721 0.279 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.721 0.279 0.000
E10.1 With ketoacidosis
0.721 0.279 0.000
F99-F99 Unspecified mental disorder
0.720 0.280 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.720 0.280 0.000
F40 Phobic anxiety disorders
0.719 0.281 0.000
R53 Malaise and fatigue
0.719 0.281 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.718 0.282 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J18.9 Pneumonia, unspecified
0.716 0.284 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
D55-D59 Haemolytic anaemias
0.716 0.284 0.000
E85 Amyloidosis
0.714 0.285 0.000
E84 Cystic fibrosis
0.714 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.714 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.714 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.714 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.714 0.285 0.000
E74 Other disorders of carbohydrate metabolism
0.714 0.285 0.000
E73 Lactose intolerance
0.714 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.714 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.714 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.714 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.714 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.714 0.286 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.714 0.286 0.000
D74 Methaemoglobinaemia
0.714 0.286 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.714 0.286 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.714 0.286 0.000
E10.3 With ophthalmic complications
0.714 0.286 0.000
Chapter XXII Codes for special purposes
0.714 0.286 0.000
L90 Atrophic disorders of skin
0.713 0.287 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.712 0.287 0.000
C77.8 Lymph nodes of multiple regions
0.711 0.289 0.000
C91 Lymphoid leukaemia
0.711 0.289 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.710 0.290 0.000
E87.4 Mixed disorder of acid-base balance
0.710 0.290 0.000
E87.3 Alkalosis
0.710 0.290 0.000
T33-T35 Frostbite
0.709 0.291 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.709 0.291 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.709 0.291 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.709 0.291 0.000
T00-T07 Injuries involving multiple body regions
0.709 0.291 0.000
S10-S19 Injuries to the neck
0.709 0.291 0.000
E83.4 Disorders of magnesium metabolism
0.707 0.293 0.000
H80-H83 Diseases of inner ear
0.706 0.294 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X60-X84 Intentional self-harm
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V80-V89 Other land transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V20-V29 Motorcycle rider injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
I61 Intracerebral haemorrhage
0.705 0.295 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.704 0.296 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.703 0.296 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.703 0.297 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.703 0.297 0.000
R61 Hyperhidrosis
0.703 0.297 0.000
J41 Simple and mucopurulent chronic bronchitis
0.701 0.299 0.000
V10-V19 Pedal cyclist injured in transport accident
0.701 0.299 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.700 0.300 0.000
R50 Fever of unknown origin
0.700 0.300 0.000
E27 Other disorders of adrenal gland
0.699 0.301 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.698 0.302 0.000
L10-L14 Bullous disorders
0.698 0.302 0.000
E23 Hypofunction and other disorders of pituitary gland
0.698 0.302 0.000
Y44 Agents primarily affecting blood constituents
0.697 0.303 0.000
C77.9 Lymph node, unspecified
0.697 0.303 0.000
S80-S89 Injuries to the knee and lower leg
0.696 0.304 0.000
J84 Other interstitial pulmonary diseases
0.696 0.304 0.000
Y84.0 Cardiac catheterisation
0.696 0.304 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.695 0.305 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.695 0.305 0.000
Y84.6 Urinary catheterisation
0.694 0.306 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.694 0.306 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.694 0.306 0.000
C77.1 Intrathoracic lymph nodes
0.693 0.307 0.000
L50-L54 Urticaria and erythema
0.693 0.307 0.000
J98.4 Other disorders of lung
0.693 0.307 0.000
T79-T79 Certain early complications of trauma
0.692 0.308 0.000
B99-B99 Other infectious diseases
0.692 0.308 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.692 0.308 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.692 0.308 0.000
B65-B83 Helminthiases
0.692 0.308 0.000
B50-B64 Protozoal diseases
0.692 0.308 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.692 0.308 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.692 0.308 0.000
A80-A89 Viral infections of the central nervous system
0.692 0.308 0.000
A75-A79 Rickettsioses
0.692 0.308 0.000
A70-A74 Other diseases caused by chlamydiae
0.692 0.308 0.000
A65-A69 Other spirochaetal diseases
0.692 0.308 0.000
A20-A28 Certain zoonotic bacterial diseases
0.692 0.308 0.000
A15-A19 Tuberculosis
0.692 0.308 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.691 0.309 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.691 0.309 0.000
T87 Complications peculiar to reattachment and amputation
0.690 0.310 0.000
T86 Failure and rejection of transplanted organs and tissues
0.690 0.310 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.690 0.310 0.000
C95 Leukaemia of unspecified cell type
0.690 0.310 0.000
C94 Other leukaemias of specified cell type
0.690 0.310 0.000
C93 Monocytic leukaemia
0.690 0.310 0.000
C88 Malignant immunoproliferative diseases
0.690 0.310 0.000
C86 Other specified types of T/NK-cell lymphoma
0.690 0.310 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.690 0.310 0.000
J60-J70 Lung diseases due to external agents
0.690 0.310 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.690 0.310 0.000
F80-F89 Disorders of psychological development
0.690 0.310 0.000
F70-F79 Mental retardation
0.690 0.310 0.000
F60-F69 Disorders of adult personality and behaviour
0.690 0.310 0.000
C80 Malignant neoplasm without specification of site
0.690 0.310 0.000
G90-G99 Other disorders of the nervous system
0.689 0.311 0.000
G25.3 Myoclonus
0.689 0.311 0.000
J46 Status asthmaticus
0.688 0.312 0.000
S60-S69 Injuries to the wrist and hand
0.688 0.312 0.000
E29 Testicular dysfunction
0.688 0.312 0.000
E21.3 Hyperparathyroidism, unspecified
0.687 0.313 0.000
S32 Fracture of lumbar spine and pelvis
0.687 0.313 0.000
D86 Sarcoidosis
0.685 0.315 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.683 0.317 0.000
J03.9 Acute tonsillitis, unspecified
0.683 0.317 0.000
C77.0 Lymph nodes of head, face and neck
0.683 0.317 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.682 0.318 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.682 0.318 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.682 0.318 0.000
Y59 Other and unspecified vaccines and biological substances
0.681 0.319 0.000
Y58 Bacterial vaccines
0.681 0.319 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.681 0.319 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.681 0.319 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.681 0.319 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.681 0.319 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.681 0.319 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.681 0.319 0.000
Y48 Anaesthetics and therapeutic gases
0.681 0.319 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.681 0.319 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.681 0.319 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.681 0.319 0.000
D72 Other disorders of white blood cells
0.681 0.319 0.000
A00-A09 Intestinal infectious diseases
0.679 0.321 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.678 0.322 0.000
Y84.1 Kidney dialysis
0.678 0.322 0.000
S00-S09 Injuries to the head
0.677 0.323 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.677 0.323 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.676 0.324 0.000
B15-B19 Viral hepatitis
0.673 0.327 0.000
R61.9 Hyperhidrosis, unspecified
0.673 0.327 0.000
E50-E64 Other nutritional deficiencies
0.671 0.329 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.671 0.329 0.000
Y40 Systemic antibiotics
0.671 0.329 0.000
J86 Pyothorax
0.670 0.329 0.000
S40-S49 Injuries to the shoulder and upper arm
0.669 0.331 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.669 0.331 0.000
C64-C68 Malignant neoplasms of urinary tract
0.669 0.331 0.000
E22 Hyperfunction of pituitary gland
0.669 0.331 0.000
I05-I09 Chronic rheumatic heart diseases
0.668 0.332 0.000
J43 Emphysema
0.668 0.332 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.668 0.332 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.668 0.332 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.668 0.332 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.668 0.332 0.000
T82.3 Mechanical complication of other vascular grafts
0.668 0.332 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.668 0.332 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.668 0.332 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.667 0.332 0.000
J96 Respiratory failure, not elsewhere classified
0.667 0.332 0.000
E13 Other specified diabetes mellitus
0.667 0.333 0.000
E12 Malnutrition-related diabetes mellitus
0.667 0.333 0.000
L85 Other epidermal thickening
0.667 0.333 0.000
A49 Bacterial infection of unspecified site
0.666 0.334 0.000
A48 Other bacterial diseases, not elsewhere classified
0.666 0.334 0.000
A44 Bartonellosis
0.666 0.334 0.000
A43 Nocardiosis
0.666 0.334 0.000
A42 Actinomycosis
0.666 0.334 0.000
A40 Streptococcal septicaemia
0.666 0.334 0.000
A39 Meningococcal infection
0.666 0.334 0.000
A37 Whooping cough
0.666 0.334 0.000
A36 Diphtheria
0.666 0.334 0.000
A32 Listeriosis
0.666 0.334 0.000
A31 Infection due to other mycobacteria
0.666 0.334 0.000
A30 Leprosy [Hansen's disease]
0.666 0.334 0.000
A46 Erysipelas
0.666 0.334 0.000
A38 Scarlet fever
0.666 0.334 0.000
A35 Other tetanus
0.666 0.334 0.000
A34 Obstetrical tetanus
0.666 0.334 0.000
A33 Tetanus neonatorum
0.666 0.334 0.000
G70-G73 Diseases of myoneural junction and muscle
0.665 0.335 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.665 0.335 0.000
G24 Dystonia
0.663 0.336 0.000
E11.3 With ophthalmic complications
0.663 0.337 0.000
F48 Other neurotic disorders
0.663 0.337 0.000
F44 Dissociative [conversion] disorders
0.663 0.337 0.000
F42 Obsessive-compulsive disorder
0.663 0.337 0.000
L89.1 Stage II decubitus ulcer
0.662 0.338 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.662 0.338 0.000
D80 Immunodeficiency with predominantly antibody defects
0.659 0.340 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.659 0.341 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.659 0.341 0.000
E28 Ovarian dysfunction
0.659 0.341 0.000
I30-I52 Other forms of heart disease
0.657 0.343 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.656 0.344 0.000
J04 Acute laryngitis and tracheitis
0.656 0.344 0.000
J01 Acute sinusitis
0.656 0.344 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.655 0.345 0.000
E34 Other endocrine disorders
0.655 0.345 0.000
E32 Diseases of thymus
0.655 0.345 0.000
E31 Polyglandular dysfunction
0.655 0.345 0.000
E30 Disorders of puberty, not elsewhere classified
0.655 0.345 0.000
E26 Hyperaldosteronism
0.655 0.345 0.000
E25 Adrenogenital disorders
0.655 0.345 0.000
E24 Cushing's syndrome
0.655 0.345 0.000
E20 Hypoparathyroidism
0.655 0.345 0.000
L89.2 Stage III decubitus ulcer
0.654 0.346 0.000
O80-O84 Delivery
0.654 0.346 0.000
E21.0 Primary hyperparathyroidism
0.653 0.347 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.653 0.347 0.000
N37 Urethral disorders in diseases classified elsewhere
0.653 0.347 0.000
N34 Urethritis and urethral syndrome
0.653 0.347 0.000
N33 Bladder disorders in diseases classified elsewhere
0.653 0.347 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.652 0.348 0.000
N39.9 Disorder of urinary system, unspecified
0.652 0.348 0.000
N99-N99 Other disorders of the genitourinary system
0.650 0.350 0.000
G30 Alzheimer's disease
0.649 0.351 0.000
T92 Sequelae of injuries of upper limb
0.649 0.351 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.648 0.351 0.000
Y57.9 Drug or medicament, unspecified
0.648 0.352 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.648 0.352 0.000
J17 Pneumonia in diseases classified elsewhere
0.648 0.352 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.648 0.352 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.648 0.352 0.000
J12 Viral pneumonia, not elsewhere classified
0.648 0.352 0.000
J11 Influenza, virus not identified
0.648 0.352 0.000
J10 Influenza due to identified influenza virus
0.648 0.352 0.000
J14 Pneumonia due to Haemophilus influenzae
0.648 0.352 0.000
J09 Influenza due to certain identified influenza virus
0.648 0.352 0.000
E87.0 Hyperosmolality and hypernatraemia
0.648 0.352 0.000
A41.4 Septicaemia due to anaerobes
0.647 0.353 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.647 0.353 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.647 0.353 0.000
Y84.2 Radiological procedure and radiotherapy
0.647 0.353 0.000
G23 Other degenerative diseases of basal ganglia
0.647 0.353 0.000
G21 Secondary Parkinsonism
0.647 0.353 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.647 0.353 0.000
G22 Parkinsonism in diseases classified elsewhere
0.647 0.353 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.646 0.353 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.646 0.353 0.000
L94 Other localised connective tissue disorders
0.646 0.353 0.000
L93 Lupus erythematosus
0.646 0.353 0.000
L87 Transepidermal elimination disorders
0.646 0.353 0.000
L88 Pyoderma gangrenosum
0.646 0.353 0.000
L86 Keratoderma in diseases classified elsewhere
0.646 0.353 0.000
L84 Corns and callosities
0.646 0.353 0.000
L83 Acanthosis nigricans
0.646 0.353 0.000
L80 Vitiligo
0.646 0.353 0.000
Y43.9 Primarily systemic agent, unspecified
0.646 0.354 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.646 0.354 0.000
Y43.6 Enzymes, not elsewhere classified
0.646 0.354 0.000
Y43.5 Acidifying and alkalising agents
0.646 0.354 0.000
Y43.2 Antineoplastic natural products
0.646 0.354 0.000
Y43.1 Antineoplastic antimetabolites
0.646 0.354 0.000
Y43.0 Antiallergic and antiemetic drugs
0.646 0.354 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.646 0.354 0.000
F45 Somatoform disorders
0.645 0.355 0.000
J21 Acute bronchiolitis
0.644 0.356 0.000
J20 Acute bronchitis
0.644 0.356 0.000
R50.9 Fever, unspecified
0.644 0.356 0.000
N36 Other disorders of urethra
0.644 0.356 0.000
J91 Pleural effusion in conditions classified elsewhere
0.643 0.357 0.000
I62 Other nontraumatic intracranial haemorrhage
0.642 0.357 0.000
S50-S59 Injuries to the elbow and forearm
0.641 0.358 0.000
C69 Malignant neoplasm of eye and adnexa
0.641 0.359 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.640 0.360 0.000
B35-B49 Mycoses
0.640 0.360 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.639 0.361 0.000
T78 Adverse effects, not elsewhere classified
0.639 0.361 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.637 0.362 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.637 0.363 0.000
F00 Dementia in Alzheimer's disease
0.637 0.363 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.636 0.364 0.000
H92 Otalgia and effusion of ear
0.636 0.364 0.000
E83.3 Disorders of phosphorus metabolism
0.636 0.364 0.000
O85-O92 Complications predominantly related to the puerperium
0.635 0.365 0.000
C90.3 Solitary plasmacytoma
0.635 0.365 0.000
C90.2 Plasmacytoma, extramedullary
0.635 0.365 0.000
C90.1 Plasma cell leukaemia
0.635 0.365 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.635 0.365 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.634 0.365 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.634 0.366 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.634 0.366 0.000
J90 Pleural effusion, not elsewhere classified
0.633 0.367 0.000
F41.8 Other specified anxiety disorders
0.633 0.367 0.000
F41.3 Other mixed anxiety disorders
0.633 0.367 0.000
N10 Acute tubulo-interstitial nephritis
0.630 0.369 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.630 0.369 0.000
E83.8 Other disorders of mineral metabolism
0.630 0.369 0.000
E83.2 Disorders of zinc metabolism
0.630 0.369 0.000
E83.0 Disorders of copper metabolism
0.630 0.369 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.630 0.370 0.000
N17-N19 Renal failure
0.629 0.371 0.000
D73.9 Disease of spleen, unspecified
0.629 0.371 0.000
D73.8 Other diseases of spleen
0.629 0.371 0.000
D73.5 Infarction of spleen
0.629 0.371 0.000
D73.4 Cyst of spleen
0.629 0.371 0.000
D73.3 Abscess of spleen
0.629 0.371 0.000
D73.2 Chronic congestive splenomegaly
0.629 0.371 0.000
D73.1 Hypersplenism
0.629 0.371 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.628 0.372 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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