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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17057381
log Bayes Factor = 1.98864
Chromosome 8   position 27,416,801  (GRCh37) Explore rs17057381 on Ensembl!
Variant rs17057381 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I60-I69 Cerebrovascular diseases
0.989 0.011 0.000
Chapter IX Diseases of the circulatory system
0.987 0.013 0.000
# Top node
0.986 0.014 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.983 0.017 0.000
I67 Other cerebrovascular diseases
0.974 0.026 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.970 0.030 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.957 0.043 0.000
I67.9 Cerebrovascular disease, unspecified
0.955 0.045 0.000
I30-I52 Other forms of heart disease
0.944 0.056 0.000
O60-O75 Complications of labour and delivery
0.942 0.058 0.000
I63 Cerebral infarction
0.928 0.072 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.928 0.072 0.000
Chapter XX External causes of morbidity and mortality
0.926 0.074 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.918 0.082 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.913 0.087 0.000
Chapter VI Diseases of the nervous system
0.886 0.114 0.000
I65.2 Occlusion and stenosis of carotid artery
0.884 0.116 0.000
E00-E07 Disorders of thyroid gland
0.871 0.129 0.000
Chapter I Certain infectious and parasitic diseases
0.861 0.139 0.000
I69 Sequelae of cerebrovascular disease
0.858 0.142 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.857 0.143 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.854 0.146 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.850 0.150 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.842 0.158 0.000
Chapter XXII Codes for special purposes
0.840 0.160 0.000
E05.9 Thyrotoxicosis, unspecified
0.838 0.162 0.000
S00-S09 Injuries to the head
0.832 0.168 0.000
O72 Postpartum haemorrhage
0.832 0.168 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.831 0.169 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.827 0.173 0.000
S50-S59 Injuries to the elbow and forearm
0.820 0.180 0.000
I74 Arterial embolism and thrombosis
0.820 0.180 0.000
S60-S69 Injuries to the wrist and hand
0.819 0.181 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.811 0.189 0.000
Chapter XIV Diseases of the genitourinary system
0.808 0.192 0.000
B95-B98 Bacterial, viral and other infectious agents
0.803 0.197 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.802 0.198 0.000
O48 Prolonged pregnancy
0.800 0.200 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.799 0.201 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.797 0.203 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.797 0.203 0.000
I33 Acute and subacute endocarditis
0.796 0.204 0.000
T66-T78 Other and unspecified effects of external causes
0.795 0.205 0.000
I67.1 Cerebral aneurysm, nonruptured
0.794 0.206 0.000
I49 Other cardiac arrhythmias
0.794 0.206 0.000
I63.9 Cerebral infarction, unspecified
0.794 0.206 0.000
I46 Cardiac arrest
0.793 0.207 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.790 0.210 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.788 0.212 0.000
Y95 Nosocomial condition
0.783 0.217 0.000
G90-G99 Other disorders of the nervous system
0.780 0.220 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.779 0.221 0.000
I62 Other nontraumatic intracranial haemorrhage
0.776 0.223 0.000
S20-S29 Injuries to the thorax
0.773 0.227 0.000
G81 Hemiplegia
0.771 0.229 0.000
E20-E35 Disorders of other endocrine glands
0.769 0.231 0.000
I50 Heart failure
0.769 0.231 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.767 0.233 0.000
I67.8 Other specified cerebrovascular diseases
0.764 0.236 0.000
I45 Other conduction disorders
0.763 0.237 0.000
O30 Multiple gestation
0.763 0.237 0.000
O40 Polyhydramnios
0.762 0.238 0.000
I44 Atrioventricular and left bundle-branch block
0.760 0.240 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.759 0.241 0.000
I60 Subarachnoid haemorrhage
0.758 0.242 0.000
N00-N08 Glomerular diseases
0.757 0.243 0.000
O72.1 Other immediate postpartum haemorrhage
0.756 0.244 0.000
O44 Placenta praevia
0.752 0.247 0.000
N30-N39 Other diseases of urinary system
0.747 0.253 0.000
S90-S99 Injuries to the ankle and foot
0.742 0.258 0.000
I71 Aortic aneurysm and dissection
0.741 0.259 0.000
I34 Nonrheumatic mitral valve disorders
0.740 0.260 0.000
S06 Intracranial injury
0.740 0.260 0.000
S10-S19 Injuries to the neck
0.739 0.261 0.000
I51 Complications and ill-defined descriptions of heart disease
0.737 0.263 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.737 0.263 0.000
O00-O08 Pregnancy with abortive outcome
0.735 0.265 0.000
G12 Spinal muscular atrophy and related syndromes
0.733 0.267 0.000
O66 Other obstructed labour
0.732 0.268 0.000
G81.9 Hemiplegia, unspecified
0.731 0.269 0.000
I77 Other disorders of arteries and arterioles
0.731 0.269 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.729 0.271 0.000
Chapter V Mental and behavioural disorders
0.729 0.271 0.000
I31 Other diseases of pericardium
0.729 0.271 0.000
N04 Nephrotic syndrome
0.725 0.275 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.723 0.277 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.721 0.279 0.000
I61 Intracerebral haemorrhage
0.720 0.280 0.000
N10-N16 Renal tubulo-interstitial diseases
0.719 0.281 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.719 0.281 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.717 0.283 0.000
I63.8 Other cerebral infarction
0.716 0.284 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.716 0.284 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.715 0.285 0.000
S52 Fracture of forearm
0.713 0.286 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.713 0.286 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.713 0.287 0.000
E70-E90 Metabolic disorders
0.710 0.290 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.710 0.290 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.709 0.291 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.709 0.291 0.000
I00-I02 Acute rheumatic fever
0.708 0.292 0.000
S62 Fracture at wrist and hand level
0.708 0.292 0.000
I46.0 Cardiac arrest with successful resuscitation
0.708 0.292 0.000
V10-V19 Pedal cyclist injured in transport accident
0.707 0.293 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.707 0.293 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.707 0.293 0.000
O85-O92 Complications predominantly related to the puerperium
0.705 0.295 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.704 0.296 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.703 0.297 0.000
N04.9 Unspecified
0.702 0.298 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.701 0.299 0.000
N35 Urethral stricture
0.701 0.299 0.000
O42 Premature rupture of membranes
0.700 0.300 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.698 0.302 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.698 0.302 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.698 0.302 0.000
I67.5 Moyamoya disease
0.698 0.302 0.000
I67.4 Hypertensive encephalopathy
0.698 0.302 0.000
I67.3 Progressive vascular leukoencephalopathy
0.698 0.302 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.698 0.302 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.698 0.302 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.697 0.303 0.000
T79-T79 Certain early complications of trauma
0.695 0.304 0.000
T33-T35 Frostbite
0.695 0.304 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.695 0.304 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.695 0.304 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.695 0.304 0.000
T00-T07 Injuries involving multiple body regions
0.695 0.304 0.000
X60-X84 Intentional self-harm
0.695 0.305 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.693 0.307 0.000
N25-N29 Other disorders of kidney and ureter
0.693 0.307 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.692 0.308 0.000
O63 Long labour
0.692 0.308 0.000
W20-W49 Exposure to inanimate mechanical forces
0.690 0.309 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.690 0.310 0.000
I33.0 Acute and subacute infective endocarditis
0.689 0.311 0.000
I70 Atherosclerosis
0.689 0.311 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.688 0.312 0.000
G12.2 Motor neuron disease
0.687 0.313 0.000
O47 False labour
0.687 0.313 0.000
Y45.0 Opioids and related analgesics
0.687 0.313 0.000
O45 Premature separation of placenta [abruptio placentae]
0.686 0.313 0.000
O43 Placental disorders
0.686 0.313 0.000
O41 Other disorders of amniotic fluid and membranes
0.686 0.313 0.000
O33 Maternal care for known or suspected disproportion
0.686 0.313 0.000
O31 Complications specific to multiple gestation
0.686 0.313 0.000
I78 Diseases of capillaries
0.684 0.315 0.000
S40-S49 Injuries to the shoulder and upper arm
0.683 0.317 0.000
E50-E64 Other nutritional deficiencies
0.682 0.318 0.000
G30-G32 Other degenerative diseases of the nervous system
0.681 0.319 0.000
S70-S79 Injuries to the hip and thigh
0.681 0.319 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.681 0.319 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.681 0.319 0.000
O36 Maternal care for other known or suspected foetal problems
0.679 0.321 0.000
I52 Other heart disorders in diseases classified elsewhere
0.677 0.323 0.000
I48 Atrial fibrillation and flutter
0.677 0.323 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.677 0.323 0.000
I41 Myocarditis in diseases classified elsewhere
0.677 0.323 0.000
I40 Acute myocarditis
0.677 0.323 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.677 0.323 0.000
I37 Pulmonary valve disorders
0.677 0.323 0.000
I36 Nonrheumatic tricuspid valve disorders
0.677 0.323 0.000
I32 Pericarditis in diseases classified elsewhere
0.677 0.323 0.000
I30 Acute pericarditis
0.677 0.323 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.675 0.324 0.000
O74 Complications of anaesthesia during labour and delivery
0.675 0.324 0.000
O73 Retained placenta and membranes, without haemorrhage
0.675 0.324 0.000
O71 Other obstetric trauma
0.675 0.324 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.675 0.324 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.675 0.324 0.000
O62 Abnormalities of forces of labour
0.675 0.324 0.000
O61 Failed induction of labour
0.675 0.324 0.000
O60 Preterm delivery
0.675 0.324 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.675 0.325 0.000
I49.0 Ventricular fibrillation and flutter
0.675 0.325 0.000
I50.9 Heart failure, unspecified
0.674 0.326 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.673 0.327 0.000
Y40 Systemic antibiotics
0.672 0.328 0.000
E04 Other non-toxic goitre
0.670 0.329 0.000
T78 Adverse effects, not elsewhere classified
0.670 0.330 0.000
I72 Other aneurysm
0.670 0.330 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.669 0.330 0.000
S52.5 Fracture of lower end of radius
0.669 0.331 0.000
O34.1 Maternal care for tumour of corpus uteri
0.667 0.333 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.666 0.334 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.666 0.334 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.666 0.334 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.666 0.334 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.665 0.334 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.665 0.335 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.665 0.335 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.665 0.335 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.665 0.335 0.000
I65.1 Occlusion and stenosis of basilar artery
0.665 0.335 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.665 0.335 0.000
S68 Traumatic amputation of wrist and hand
0.664 0.336 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.664 0.336 0.000
Y35-Y36 Legal intervention and operations of war
0.664 0.336 0.000
Y10-Y34 Event of undetermined intent
0.664 0.336 0.000
Y00-Y09 Assault
0.664 0.336 0.000
X85-X99 Assault
0.664 0.336 0.000
X50-X57 Overexertion, travel and privation
0.664 0.336 0.000
X30-X39 Exposure to forces of nature
0.664 0.336 0.000
X20-X29 Contact with venomous animals and plants
0.664 0.336 0.000
X10-X19 Contact with heat and hot substances
0.664 0.336 0.000
X00-X09 Exposure to smoke, fire and flames
0.664 0.336 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.664 0.336 0.000
W75-W84 Other accidental threats to breathing
0.664 0.336 0.000
W65-W74 Accidental drowning and submersion
0.664 0.336 0.000
W50-W64 Exposure to animate mechanical forces
0.664 0.336 0.000
V98-V99 Other and unspecified transport accidents
0.664 0.336 0.000
V95-V97 Air and space transport accidents
0.664 0.336 0.000
V90-V94 Water transport accidents
0.664 0.336 0.000
V80-V89 Other land transport accidents
0.664 0.336 0.000
V70-V79 Bus occupant injured in transport accident
0.664 0.336 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.664 0.336 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.664 0.336 0.000
V40-V49 Car occupant injured in transport accident
0.664 0.336 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.664 0.336 0.000
V01-V09 Pedestrian injured in transport accident
0.664 0.336 0.000
Chapter VIII Diseases of the ear and mastoid process
0.662 0.338 0.000
N32 Other disorders of bladder
0.662 0.338 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.662 0.338 0.000
I67.2 Cerebral atherosclerosis
0.661 0.339 0.000
Y52 Agents primarily affecting the cardiovascular system
0.658 0.341 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.658 0.342 0.000
G91 Hydrocephalus
0.658 0.342 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.655 0.345 0.000
T17 Foreign body in respiratory tract
0.655 0.345 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.655 0.345 0.000
E40-E46 Malnutrition
0.655 0.345 0.000
I44.1 Atrioventricular block, second degree
0.654 0.346 0.000
I38 Endocarditis, valve unspecified
0.653 0.347 0.000
N35.9 Urethral stricture, unspecified
0.652 0.348 0.000
G83 Other paralytic syndromes
0.650 0.350 0.000
N13 Obstructive and reflux uropathy
0.648 0.352 0.000
E06 Thyroiditis
0.648 0.352 0.000
S64 Injury of nerves at wrist and hand level
0.648 0.352 0.000
V20-V29 Motorcycle rider injured in transport accident
0.647 0.352 0.000
G95 Other diseases of spinal cord
0.647 0.353 0.000
I42 Cardiomyopathy
0.645 0.355 0.000
S00 Superficial injury of head
0.645 0.355 0.000
Y45.1 Salicylates
0.644 0.355 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.641 0.359 0.000
O69.8 Labour and delivery complicated by other cord complications
0.641 0.359 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.640 0.360 0.000
B15-B19 Viral hepatitis
0.640 0.360 0.000
A30-A49 Other bacterial diseases
0.638 0.362 0.000
S52.50 Fracture of lower end of radius (closed)
0.636 0.364 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.635 0.364 0.000
S01 Open wound of head
0.635 0.365 0.000
I49.8 Other specified cardiac arrhythmias
0.635 0.365 0.000
N05 Unspecified nephritic syndrome
0.634 0.366 0.000
E86 Volume depletion
0.633 0.367 0.000
I69.3 Sequelae of cerebral infarction
0.631 0.369 0.000
E07 Other disorders of thyroid
0.631 0.369 0.000
N17-N19 Renal failure
0.630 0.370 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.627 0.372 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.626 0.374 0.000
O20 Haemorrhage in early pregnancy
0.625 0.375 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.625 0.375 0.000
E00 Congenital iodine-deficiency syndrome
0.625 0.375 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.625 0.375 0.000
F30-F39 Mood [affective] disorders
0.625 0.375 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.624 0.376 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.624 0.376 0.000
O80-O84 Delivery
0.624 0.376 0.000
O30.0 Twin pregnancy
0.623 0.377 0.000
G70-G73 Diseases of myoneural junction and muscle
0.621 0.379 0.000
I05-I09 Chronic rheumatic heart diseases
0.620 0.379 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.620 0.380 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.620 0.380 0.000
I34.1 Mitral (valve) prolapse
0.619 0.381 0.000
B99-B99 Other infectious diseases
0.617 0.383 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.617 0.383 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.617 0.383 0.000
B65-B83 Helminthiases
0.617 0.383 0.000
B50-B64 Protozoal diseases
0.617 0.383 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.617 0.383 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.617 0.383 0.000
A80-A89 Viral infections of the central nervous system
0.617 0.383 0.000
A75-A79 Rickettsioses
0.617 0.383 0.000
A70-A74 Other diseases caused by chlamydiae
0.617 0.383 0.000
A65-A69 Other spirochaetal diseases
0.617 0.383 0.000
A20-A28 Certain zoonotic bacterial diseases
0.617 0.383 0.000
A15-A19 Tuberculosis
0.617 0.383 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.617 0.383 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.615 0.385 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.615 0.385 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.615 0.385 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.615 0.385 0.000
O97 Death from sequelae of direct obstetric causes
0.615 0.385 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.615 0.385 0.000
O95 Obstetric death of unspecified cause
0.615 0.385 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.615 0.385 0.000
O70 Perineal laceration during delivery
0.614 0.386 0.000
Y59 Other and unspecified vaccines and biological substances
0.612 0.387 0.000
Y58 Bacterial vaccines
0.612 0.387 0.000
Y57 Other and unspecified drugs and medicaments
0.612 0.387 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.612 0.387 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.612 0.387 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.612 0.387 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.612 0.387 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.612 0.387 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.612 0.387 0.000
Y48 Anaesthetics and therapeutic gases
0.612 0.387 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.612 0.387 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.612 0.387 0.000
Y44 Agents primarily affecting blood constituents
0.612 0.387 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.612 0.387 0.000
S80-S89 Injuries to the knee and lower leg
0.612 0.388 0.000
T93 Sequelae of injuries of lower limb
0.612 0.388 0.000
E27 Other disorders of adrenal gland
0.610 0.390 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.610 0.390 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.610 0.390 0.000
I50.0 Congestive heart failure
0.610 0.390 0.000
E05.8 Other thyrotoxicosis
0.609 0.390 0.000
E05.5 Thyroid crisis or storm
0.609 0.390 0.000
E05.4 Thyrotoxicosis factitia
0.609 0.390 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.609 0.390 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.609 0.390 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.609 0.390 0.000
I45.2 Bifascicular block
0.609 0.391 0.000
Q80-Q89 Other congenital malformations
0.608 0.392 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.608 0.392 0.000
I45.9 Conduction disorder, unspecified
0.607 0.393 0.000
S62.5 Fracture of thumb
0.606 0.394 0.000
O44.1 Placenta praevia with haemorrhage
0.606 0.394 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.605 0.395 0.000
I31.9 Disease of pericardium, unspecified
0.605 0.395 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.604 0.396 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.604 0.396 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.604 0.396 0.000
Y98 Lifestyle-related condition
0.604 0.396 0.000
Y97 Environmental-pollution-related condition
0.604 0.396 0.000
Y96 Work-related condition
0.604 0.396 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.603 0.397 0.000
S67 Crushing injury of wrist and hand
0.602 0.398 0.000
I44.0 Atrioventricular block, first degree
0.602 0.398 0.000
S27 Injury of other and unspecified intrathoracic organs
0.601 0.398 0.000
T18 Foreign body in alimentary tract
0.599 0.401 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.598 0.402 0.000
S08 Traumatic amputation of part of head
0.597 0.403 0.000
S07 Crushing injury of head
0.597 0.403 0.000
S05 Injury of eye and orbit
0.597 0.403 0.000
S04 Injury of cranial nerves
0.597 0.403 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.597 0.403 0.000
O72.3 Postpartum coagulation defects
0.596 0.404 0.000
O72.0 Third-stage haemorrhage
0.596 0.404 0.000
I10-I15 Hypertensive diseases
0.596 0.404 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.596 0.404 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.596 0.404 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.596 0.404 0.000
O34.6 Maternal care for abnormality of vagina
0.596 0.404 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.596 0.404 0.000
O34.4 Maternal care for other abnormalities of cervix
0.596 0.404 0.000
O34.3 Maternal care for cervical incompetence
0.596 0.404 0.000
O34.0 Maternal care for congenital malformation of uterus
0.596 0.404 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.596 0.404 0.000
G82 Paraplegia and tetraplegia
0.593 0.407 0.000
G80 Infantile cerebral palsy
0.593 0.407 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.592 0.408 0.000
S06.2 Diffuse brain injury
0.592 0.408 0.000
S99 Other and unspecified injuries of ankle and foot
0.591 0.409 0.000
Q50-Q56 Congenital malformations of genital organs
0.591 0.409 0.000
I49.9 Cardiac arrhythmia, unspecified
0.590 0.410 0.000
I51.7 Cardiomegaly
0.590 0.410 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.589 0.410 0.000
I77.6 Arteritis, unspecified
0.589 0.411 0.000
S59 Other and unspecified injuries of forearm
0.588 0.412 0.000
S58 Traumatic amputation of forearm
0.588 0.412 0.000
S57 Crushing injury of forearm
0.588 0.412 0.000
S56 Injury of muscle and tendon at forearm level
0.588 0.412 0.000
S55 Injury of blood vessels at forearm level
0.588 0.412 0.000
S54 Injury of nerves at forearm level
0.588 0.412 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.588 0.412 0.000
S50 Superficial injury of forearm
0.588 0.412 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.588 0.412 0.000
I74.8 Embolism and thrombosis of other arteries
0.588 0.412 0.000
I74.5 Embolism and thrombosis of iliac artery
0.588 0.412 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.588 0.412 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.588 0.412 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.588 0.412 0.000
S69 Other and unspecified injuries of wrist and hand
0.587 0.413 0.000
S65 Injury of blood vessels at wrist and hand level
0.587 0.413 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.587 0.413 0.000
S60 Superficial injury of wrist and hand
0.587 0.413 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.586 0.414 0.000
S02 Fracture of skull and facial bones
0.585 0.414 0.000
G93 Other disorders of brain
0.585 0.415 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.585 0.415 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.585 0.415 0.000
S51 Open wound of forearm
0.584 0.415 0.000
N32.8 Other specified disorders of bladder
0.584 0.416 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.583 0.417 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.583 0.417 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.581 0.418 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.581 0.418 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.581 0.418 0.000
O69.3 Labour and delivery complicated by short cord
0.581 0.418 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.581 0.418 0.000
S06.0 Concussion
0.581 0.419 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.581 0.419 0.000
S29 Other and unspecified injuries of thorax
0.580 0.420 0.000
N99-N99 Other disorders of the genitourinary system
0.580 0.420 0.000
U80 Agent resistant to penicillin and related antibiotics
0.579 0.421 0.000
O02 Other abnormal products of conception
0.578 0.422 0.000
B07 Viral warts
0.576 0.424 0.000
E89.0 Postprocedural hypothyroidism
0.576 0.424 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.575 0.425 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.575 0.425 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.575 0.425 0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures
0.575 0.425 0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation
0.575 0.425 0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs
0.575 0.425 0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol
0.575 0.425 0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother
0.575 0.425 0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus
0.575 0.425 0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus
0.575 0.425 0.000
O42.9 Premature rupture of membranes, unspecified
0.574 0.426 0.000
S12 Fracture of neck
0.573 0.427 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.573 0.427 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.573 0.427 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.573 0.427 0.000
Q35-Q37 Cleft lip and cleft palate
0.573 0.427 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.573 0.427 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.573 0.427 0.000
Q00-Q07 Congenital malformations of the nervous system
0.573 0.427 0.000
S06.5 Traumatic subdural haemorrhage
0.572 0.428 0.000
I45.5 Other specified heart block
0.572 0.428 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.571 0.428 0.000
G11 Hereditary ataxia
0.571 0.428 0.000
G14 Postpolio syndrome
0.571 0.428 0.000
G10 Huntington's disease
0.571 0.428 0.000
Q60-Q64 Congenital malformations of the urinary system
0.571 0.429 0.000
T19 Foreign body in genito-urinary tract
0.571 0.429 0.000
T15 Foreign body on external eye
0.571 0.429 0.000
T16 Foreign body in ear
0.571 0.429 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.571 0.429 0.000
I33.9 Acute endocarditis, unspecified
0.571 0.429 0.000
T75 Effects of other external causes
0.570 0.430 0.000
T74 Maltreatment syndromes
0.570 0.430 0.000
T73 Effects of other deprivation
0.570 0.430 0.000
T70 Effects of air pressure and water pressure
0.570 0.430 0.000
T69 Other effects of reduced temperature
0.570 0.430 0.000
T67 Effects of heat and light
0.570 0.430 0.000
T71 Asphyxiation
0.570 0.430 0.000
T68 Hypothermia
0.570 0.430 0.000
T66 Unspecified effects of radiation
0.570 0.430 0.000
X58 Exposure to other specified factors
0.570 0.430 0.000
E29 Testicular dysfunction
0.570 0.430 0.000
I49.2 Junctional premature depolarisation
0.569 0.431 0.000
I49.1 Atrial premature depolarisation
0.569 0.431 0.000
I46.1 Sudden cardiac death, so described
0.568 0.432 0.000
N35.8 Other urethral stricture
0.568 0.432 0.000
E22 Hyperfunction of pituitary gland
0.568 0.432 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.567 0.433 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.567 0.433 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.566 0.434 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.566 0.434 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.565 0.435 0.000
O29 Complications of anaesthesia during pregnancy
0.565 0.435 0.000
O28 Abnormal findings on antenatal screening of mother
0.565 0.435 0.000
O24 Diabetes mellitus in pregnancy
0.565 0.435 0.000
O23 Infections of genito-urinary tract in pregnancy
0.565 0.435 0.000
O22 Venous complications in pregnancy
0.565 0.435 0.000
O21 Excessive vomiting in pregnancy
0.565 0.435 0.000
O25 Malnutrition in pregnancy
0.565 0.435 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.565 0.435 0.000
N30 Cystitis
0.563 0.437 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.562 0.437 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.562 0.438 0.000
I73 Other peripheral vascular diseases
0.560 0.440 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.559 0.440 0.000
Y85 Sequelae of transport accidents
0.559 0.441 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.559 0.441 0.000
G96 Other disorders of central nervous system
0.559 0.441 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.559 0.441 0.000
G90 Disorders of autonomic nervous system
0.559 0.441 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.559 0.441 0.000
G92 Toxic encephalopathy
0.559 0.441 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.558 0.442 0.000
Y45.8 Other analgesics and antipyretics
0.558 0.442 0.000
Y45.5 4-Aminophenol derivatives
0.558 0.442 0.000
Y45.4 Antirheumatics
0.558 0.442 0.000
Y45.2 Propionic acid derivatives
0.558 0.442 0.000
T78.2 Anaphylactic shock, unspecified
0.558 0.442 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.557 0.443 0.000
I62.1 Nontraumatic extradural haemorrhage
0.557 0.443 0.000
G20-G26 Extrapyramidal and movement disorders
0.556 0.444 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.556 0.444 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.554 0.446 0.000
S26 Injury of heart
0.554 0.446 0.000
S25 Injury of blood vessels of thorax
0.554 0.446 0.000
S24 Injury of nerves and spinal cord at thorax level
0.554 0.446 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.554 0.446 0.000
S21 Open wound of thorax
0.554 0.446 0.000
O63.9 Long labour, unspecified
0.554 0.446 0.000
T17.2 Foreign body in pharynx
0.553 0.447 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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