TreeWAS – Variant ID: rs17060993

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D12.8 Rectum	0.016	0.984	0.000
K51.9 Ulcerative colitis, unspecified	0.016	0.984	0.000
K51 Ulcerative colitis	0.011	0.989	0.000
K51.4 Pseudopolyposis of colon	0.010	0.990	0.000
K51.8 Other ulcerative colitis	0.010	0.990	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.009	0.990	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.009	0.991	0.000
K51.5 Mucosal proctocolitis	0.009	0.991	0.000
N60 Benign mammary dysplasia	0.009	0.991	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.008	0.992	0.000
N60.8 Other benign mammary dysplasias	0.008	0.992	0.000
N60.2 Fibroadenosis of breast	0.008	0.992	0.000
N60.0 Solitary cyst of breast	0.008	0.992	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.007	0.993	0.000
N60.1 Diffuse cystic mastopathy	0.007	0.993	0.000
N60.4 Mammary duct ectasia	0.007	0.993	0.000
N61 Inflammatory disorders of breast	0.007	0.993	0.000
N60.9 Benign mammary dysplasia, unspecified	0.006	0.994	0.000
N60.3 Fibrosclerosis of breast	0.006	0.994	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
N60-N64 Disorders of breast	0.006	0.994	0.000
K51.2 Ulcerative (chronic) proctitis	0.006	0.994	0.000
M81.9 Osteoporosis, unspecified	0.005	0.994	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.005	0.995	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
G35 Multiple sclerosis	0.005	0.995	0.000
N62 Hypertrophy of breast	0.004	0.995	0.000
B37.3 Candidiasis of vulva and vagina	0.004	0.996	0.000
R30.0 Dysuria	0.004	0.996	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
I67.9 Cerebrovascular disease, unspecified	0.004	0.996	0.000
K50-K52 Noninfective enteritis and colitis	0.004	0.996	0.000
E78.5 Hyperlipidaemia, unspecified	0.004	0.996	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.004	0.996	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.004	0.996	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.004	0.996	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.004	0.996	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.004	0.996	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.004	0.996	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.004	0.996	0.000
C44.6 Skin of upper limb, including shoulder	0.004	0.996	0.000
C44.7 Skin of lower limb, including hip	0.004	0.996	0.000
N64 Other disorders of breast	0.004	0.996	0.000
N64.1 Fat necrosis of breast	0.004	0.996	0.000
M50.0 Cervical disk disorder with myelopathy	0.004	0.996	0.000
Z51.3 Blood transfusion without reported diagnosis	0.004	0.996	0.000
N95.0 Postmenopausal bleeding	0.000	0.996	0.004
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.004	0.996	0.000
I67 Other cerebrovascular diseases	0.004	0.996	0.000
I67.2 Cerebral atherosclerosis	0.004	0.996	0.000
M81 Osteoporosis without pathological fracture	0.003	0.996	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
M81.98 Osteoporosis, unspecified (Other)	0.003	0.997	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
N63 Unspecified lump in breast	0.003	0.997	0.000
N64.9 Disorder of breast, unspecified	0.003	0.997	0.000
K50 Crohn's disease [regional enteritis]	0.003	0.997	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.003	0.997	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.003	0.997	0.000
K04.6 Periapical abscess with sinus	0.003	0.997	0.000
N64.3 Galactorrhoea not associated with childbirth	0.003	0.997	0.000
N64.2 Atrophy of breast	0.003	0.997	0.000
N64.0 Fissure and fistula of nipple	0.003	0.997	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.003	0.997	0.000
N64.4 Mastodynia	0.003	0.997	0.000
K50.8 Other Crohn's disease	0.003	0.997	0.000
C44 Other malignant neoplasms of skin	0.003	0.997	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
I67.1 Cerebral aneurysm, nonruptured	0.003	0.997	0.000
B37 Candidiasis	0.003	0.997	0.000
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
Y43.3 Other antineoplastic drugs	0.003	0.997	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.003	0.997	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.003	0.997	0.000
I67.5 Moyamoya disease	0.003	0.997	0.000
I67.4 Hypertensive encephalopathy	0.003	0.997	0.000
I67.3 Progressive vascular leukoencephalopathy	0.003	0.997	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.003	0.997	0.000
M81.8 Other osteoporosis	0.003	0.997	0.000
M81.6 Localised osteoporosis [Lequesne]	0.003	0.997	0.000
M81.5 Idiopathic osteoporosis	0.003	0.997	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.003	0.997	0.000
M81.2 Osteoporosis of disuse	0.003	0.997	0.000
M81.1 Postoophorectomy osteoporosis	0.003	0.997	0.000
M81.0 Postmenopausal osteoporosis	0.003	0.997	0.000
K52 Other non-infective gastro-enteritis and colitis	0.003	0.997	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.003	0.997	0.000
B37.1 Pulmonary candidiasis	0.003	0.997	0.000
C44.1 Skin of eyelid, including canthus	0.003	0.997	0.000
G91.9 Hydrocephalus, unspecified	0.003	0.997	0.000
K50.1 Crohn's disease of large intestine	0.003	0.997	0.000
G91 Hydrocephalus	0.003	0.997	0.000
Y43 Primarily systemic agents	0.003	0.997	0.000
E10.9 Without complications	0.000	0.997	0.003
G99.2 Myelopathy in diseases classified elsewhere	0.003	0.997	0.000
G90-G99 Other disorders of the nervous system	0.003	0.997	0.000
C44.4 Skin of scalp and neck	0.003	0.997	0.000
G25 Other extrapyramidal and movement disorders	0.003	0.997	0.000
B37.0 Candidal stomatitis	0.003	0.997	0.000
Y46.4 Iminostilbenes	0.003	0.997	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.003	0.997	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.002
G36 Other acute disseminated demyelination	0.002	0.997	0.000
C44.0 Skin of lip	0.003	0.997	0.000
I77.1 Stricture of artery	0.003	0.997	0.000
G37 Other demyelinating diseases of central nervous system	0.002	0.997	0.000
G96 Other disorders of central nervous system	0.002	0.997	0.000
G96.0 Cerebrospinal fluid leak	0.002	0.997	0.000
Y40.8 Other systemic antibiotics	0.002	0.997	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.997	0.000
I77 Other disorders of arteries and arterioles	0.003	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.997	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.002	0.997	0.000
C44.8 Overlapping lesion of skin	0.002	0.997	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.002	0.998	0.000
B37.7 Candidal septicaemia	0.002	0.998	0.000
B37.6 Candidal endocarditis	0.002	0.998	0.000
B37.5 Candidal meningitis	0.002	0.998	0.000
B37.4 Candidiasis of other urogenital sites	0.002	0.998	0.000
B37.2 Candidiasis of skin and nail	0.002	0.998	0.000
I67.8 Other specified cerebrovascular diseases	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.002	0.998	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.002	0.998	0.000
G90 Disorders of autonomic nervous system	0.002	0.998	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.002	0.998	0.000
I73.0 Raynaud's syndrome	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.48 Drug-induced osteoporosis (Other)	0.002	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.998	0.000
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
G91.1 Obstructive hydrocephalus	0.002	0.998	0.000
K52.3 Indeterminate colitis	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
I73 Other peripheral vascular diseases	0.002	0.998	0.000
G95 Other diseases of spinal cord	0.002	0.998	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.002	0.998	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.002	0.998	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.002	0.998	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.002	0.998	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.002	0.998	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.002	0.998	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.002	0.998	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.002	0.998	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.002	0.998	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.002	0.998	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.002	0.998	0.000
M81.28 Osteoporosis of disuse (Other)	0.002	0.998	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.002	0.998	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.002	0.998	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.002	0.998	0.000
M81.24 Osteoporosis of disuse (Hand)	0.002	0.998	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.002	0.998	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.002	0.998	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.002	0.998	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.002	0.998	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.002	0.998	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.002	0.998	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.002	0.998	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.002	0.998	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.002	0.998	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.58 Idiopathic osteoporosis (Other)	0.002	0.998	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.002	0.998	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.002	0.998	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.002	0.998	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.002	0.998	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.002	0.998	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.002	0.998	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.002	0.998	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.002	0.998	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.002	0.998	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.002	0.998	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.002	0.998	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.002	0.998	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.002	0.998	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.002	0.998	0.000
M81.89 Other osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.88 Other osteoporosis (Other)	0.002	0.998	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.86 Other osteoporosis (Lower leg)	0.002	0.998	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.84 Other osteoporosis (Hand)	0.002	0.998	0.000
M81.83 Other osteoporosis (Forearm)	0.002	0.998	0.000
M81.82 Other osteoporosis (Upper arm)	0.002	0.998	0.000
M81.81 Other osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.80 Other osteoporosis (Multiple sites)	0.002	0.998	0.000
B37.9 Candidiasis, unspecified	0.002	0.998	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.002	0.998	0.000
K50.0 Crohn's disease of small intestine	0.002	0.998	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.002	0.998	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.002	0.998	0.000
G44.0 Cluster headache syndrome	0.002	0.998	0.000
G91.8 Other hydrocephalus	0.002	0.998	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.002	0.998	0.000
G91.2 Normal-pressure hydrocephalus	0.002	0.998	0.000
G91.0 Communicating hydrocephalus	0.002	0.998	0.000
I71 Aortic aneurysm and dissection	0.002	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.002	0.998	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.002	0.998	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.002	0.998	0.000
G92 Toxic encephalopathy	0.002	0.998	0.000
F31.9 Bipolar affective disorder, unspecified	0.002	0.998	0.000
G90.3 Multisystem degeneration	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.002	0.998	0.000
G25.5 Other chorea	0.002	0.998	0.000
G25.4 Drug-induced chorea	0.002	0.998	0.000
G25.3 Myoclonus	0.002	0.998	0.000
G25.2 Other specified forms of tremor	0.002	0.998	0.000
G25.1 Drug-induced tremor	0.002	0.998	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.002	0.998	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.002	0.998	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.002	0.998	0.000
I63 Cerebral infarction	0.002	0.998	0.000
C44.2 Skin of ear and external auricular canal	0.002	0.998	0.000
G36.9 Acute disseminated demyelination, unspecified	0.002	0.998	0.000
G36.8 Other specified acute disseminated demyelination	0.002	0.998	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.002	0.998	0.000
G36.0 Neuromyelitis optica [Devic]	0.002	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
G90.2 Horner's syndrome	0.002	0.998	0.000
N64.8 Other specified disorders of breast	0.002	0.998	0.001
G37.8 Other specified demyelinating diseases of central nervous system	0.002	0.998	0.000
G37.5 Concentric sclerosis [Balo]	0.002	0.998	0.000
G37.4 Subacute necrotising myelitis	0.002	0.998	0.000
G37.2 Central pontine myelinolysis	0.002	0.998	0.000
G37.1 Central demyelination of corpus callosum	0.002	0.998	0.000
G37.0 Diffuse sclerosis	0.002	0.998	0.000
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
G96.9 Disorder of central nervous system, unspecified	0.002	0.998	0.000
G96.8 Other specified disorders of central nervous system	0.002	0.998	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.002	0.998	0.000
I77.8 Other specified disorders of arteries and arterioles	0.002	0.998	0.000
I77.5 Necrosis of artery	0.002	0.998	0.000
I77.4 Coeliac artery compression syndrome	0.002	0.998	0.000
I77.3 Arterial fibromuscular dysplasia	0.002	0.998	0.000
I77.2 Rupture of artery	0.002	0.998	0.000
I77.0 Arteriovenous fistula, acquired	0.002	0.998	0.000
K50.9 Crohn's disease, unspecified	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.002	0.998	0.000
G20-G26 Extrapyramidal and movement disorders	0.002	0.998	0.000
N64.5 Other signs and symptoms in breast	0.002	0.998	0.000
G44 Other headache syndromes	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
I77.6 Arteritis, unspecified	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
G43.9 Migraine, unspecified	0.002	0.998	0.000
I73.9 Peripheral vascular disease, unspecified	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
I70 Atherosclerosis	0.002	0.998	0.000
Chapter VI Diseases of the nervous system	0.002	0.998	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.002	0.998	0.000
G90.8 Other disorders of autonomic nervous system	0.002	0.998	0.000
G90.4 Autonomic dysreflexia	0.002	0.998	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.002	0.998	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.002	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.002	0.998	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
G43 Migraine	0.002	0.998	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
F31 Bipolar affective disorder	0.002	0.998	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.998	0.002
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.002	0.998	0.000
I73.8 Other specified peripheral vascular diseases	0.002	0.998	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
G95.2 Cord compression, unspecified	0.002	0.998	0.000
G95.0 Syringomyelia and syringobulbia	0.002	0.998	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.002	0.998	0.000
I60-I69 Cerebrovascular diseases	0.002	0.998	0.000
G25.0 Essential tremor	0.002	0.998	0.000
G95.8 Other specified diseases of spinal cord	0.002	0.998	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
K04 Diseases of pulp and periapical tissues	0.002	0.998	0.000
M50 Cervical disk disorders	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.002	0.998	0.000
G95.1 Vascular myelopathies	0.002	0.998	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.002	0.998	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.002	0.998	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.002	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.000	0.998	0.002
G24 Dystonia	0.002	0.998	0.000
G40-G47 Episodic and paroxysmal disorders	0.002	0.998	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.002	0.998	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.002	0.998	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.002	0.998	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.002	0.998	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.002	0.998	0.000
K52.1 Toxic gastro-enteritis and colitis	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M80-M85 Disorders of bone density and structure	0.002	0.998	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.002	0.998	0.000
R87.6 Abnormal cytological findings	0.002	0.998	0.000
T82.1 Mechanical complication of cardiac electronic device	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.002	0.998	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.002	0.998	0.000
G94.1 Hydrocephalus in neoplastic disease	0.002	0.998	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
G30-G32 Other degenerative diseases of the nervous system	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
G43.1 Migraine with aura [classical migraine]	0.002	0.998	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.002	0.998	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.002	0.998	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.002	0.998	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.002	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.002	0.998	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.002	0.998	0.000
M50.9 Cervical disk disorder, unspecified	0.002	0.998	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.002	0.998	0.000
I78 Diseases of capillaries	0.002	0.998	0.000
B35.3 Tinea pedis	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.002	0.998	0.000
I63.9 Cerebral infarction, unspecified	0.002	0.998	0.000
K04.7 Periapical abscess without sinus	0.002	0.998	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.001	0.998	0.000
G24.9 Dystonia, unspecified	0.002	0.998	0.000
G44.8 Other specified headache syndromes	0.002	0.998	0.000
G44.3 Chronic posttraumatic headache	0.002	0.998	0.000
G44.1 Vascular headache, not elsewhere classified	0.002	0.998	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
G23 Other degenerative diseases of basal ganglia	0.002	0.998	0.000
G21 Secondary Parkinsonism	0.002	0.998	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.002	0.998	0.000
G22 Parkinsonism in diseases classified elsewhere	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.002	0.998	0.000
B35-B49 Mycoses	0.002	0.998	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.002	0.998	0.000
I70.9 Generalised and unspecified atherosclerosis	0.002	0.998	0.000
I70.8 Atherosclerosis of other arteries	0.002	0.998	0.000
I70.1 Atherosclerosis of renal artery	0.002	0.998	0.000
I71.0 Dissection of aorta [any part]	0.002	0.998	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.998	0.002
K04.0 Pulpitis	0.002	0.998	0.000
M89.0 Algoneurodystrophy	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations