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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17075816
log Bayes Factor = 11.6996
Chromosome 6   position 114,376,866  (GRCh37) Explore rs17075816 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
D12.8 Rectum
1.000 0.000 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.999 0.001 0.000
F30-F39 Mood [affective] disorders
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.998 0.002 0.000
D10-D36 Benign neoplasms
0.998 0.002 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.990 0.010 0.000
Chapter VI Diseases of the nervous system
0.988 0.012 0.000
F31 Bipolar affective disorder
0.978 0.022 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.973 0.027 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.971 0.029 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.966 0.034 0.000
S00-S09 Injuries to the head
0.965 0.035 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.962 0.038 0.000
O60-O75 Complications of labour and delivery
0.961 0.039 0.000
F32 Depressive episode
0.959 0.041 0.000
G35 Multiple sclerosis
0.953 0.047 0.000
F31.9 Bipolar affective disorder, unspecified
0.953 0.047 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.952 0.048 0.000
Chapter VIII Diseases of the ear and mastoid process
0.948 0.052 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.948 0.052 0.000
Chapter XX External causes of morbidity and mortality
0.944 0.056 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.944 0.056 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.940 0.060 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.934 0.066 0.000
O70 Perineal laceration during delivery
0.929 0.071 0.000
F33 Recurrent depressive disorder
0.925 0.075 0.000
G90-G99 Other disorders of the nervous system
0.921 0.079 0.000
H65-H75 Diseases of middle ear and mastoid
0.918 0.082 0.000
Chapter X Diseases of the respiratory system
0.914 0.086 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.912 0.088 0.000
F32.9 Depressive episode, unspecified
0.912 0.088 0.000
S01 Open wound of head
0.910 0.090 0.000
D12.3 Transverse colon
0.900 0.100 0.000
F10.0 Acute intoxication
0.899 0.101 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.898 0.102 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.898 0.102 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.893 0.107 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.892 0.108 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.888 0.112 0.000
D12.6 Colon, unspecified
0.886 0.114 0.000
J30-J39 Other diseases of upper respiratory tract
0.884 0.116 0.000
C15-C26 Malignant neoplasms of digestive organs
0.883 0.117 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.882 0.118 0.000
T39.1 4-Aminophenol derivatives
0.881 0.119 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.880 0.119 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.873 0.127 0.000
D12.4 Descending colon
0.872 0.128 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.870 0.130 0.000
S01.8 Open wound of other parts of head
0.864 0.136 0.000
O70.0 First degree perineal laceration during delivery
0.863 0.137 0.000
Chapter XXII Codes for special purposes
0.861 0.139 0.000
F10.1 Harmful use
0.857 0.143 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.857 0.143 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.854 0.146 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.848 0.152 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.843 0.157 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.840 0.160 0.000
H72 Perforation of tympanic membrane
0.839 0.161 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.839 0.161 0.000
F60-F69 Disorders of adult personality and behaviour
0.836 0.164 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.835 0.165 0.000
J33 Nasal polyp
0.832 0.168 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.830 0.170 0.000
S20-S29 Injuries to the thorax
0.829 0.171 0.000
G93 Other disorders of brain
0.825 0.175 0.000
D12.0 Caecum
0.823 0.177 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.822 0.178 0.000
O70.1 Second degree perineal laceration during delivery
0.822 0.178 0.000
Y83.6 Removal of other organ (partial) (total)
0.821 0.179 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.819 0.181 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.817 0.183 0.000
S70-S79 Injuries to the hip and thigh
0.814 0.186 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.811 0.189 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.810 0.190 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.808 0.192 0.000
D24 Benign neoplasm of breast
0.808 0.192 0.000
S00 Superficial injury of head
0.802 0.198 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.799 0.201 0.000
H74 Other disorders of middle ear and mastoid
0.796 0.204 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.795 0.205 0.000
G96 Other disorders of central nervous system
0.795 0.205 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.790 0.210 0.000
F20 Schizophrenia
0.787 0.212 0.000
S90-S99 Injuries to the ankle and foot
0.787 0.213 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.787 0.213 0.000
J90-J94 Other diseases of pleura
0.786 0.214 0.000
T86 Failure and rejection of transplanted organs and tissues
0.786 0.214 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.783 0.217 0.000
J32 Chronic sinusitis
0.780 0.220 0.000
D34 Benign neoplasm of thyroid gland
0.780 0.220 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.779 0.221 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.778 0.222 0.000
X60-X84 Intentional self-harm
0.778 0.222 0.000
D16 Benign neoplasm of bone and articular cartilage
0.777 0.222 0.000
F30 Manic episode
0.775 0.225 0.000
S50-S59 Injuries to the elbow and forearm
0.773 0.227 0.000
S10-S19 Injuries to the neck
0.773 0.227 0.000
H80-H83 Diseases of inner ear
0.773 0.227 0.000
T88.5 Other complications of anaesthesia
0.772 0.228 0.000
D27 Benign neoplasm of ovary
0.772 0.228 0.000
D10 Benign neoplasm of mouth and pharynx
0.771 0.229 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.770 0.230 0.000
D23 Other benign neoplasms of skin
0.769 0.231 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.769 0.231 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.768 0.232 0.000
D46 Myelodysplastic syndromes
0.768 0.232 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.768 0.232 0.000
T66-T78 Other and unspecified effects of external causes
0.767 0.233 0.000
S02 Fracture of skull and facial bones
0.767 0.233 0.000
G70-G73 Diseases of myoneural junction and muscle
0.766 0.234 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.766 0.234 0.000
F03 Unspecified dementia
0.764 0.236 0.000
J33.0 Polyp of nasal cavity
0.763 0.237 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.763 0.237 0.000
O42 Premature rupture of membranes
0.763 0.237 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.760 0.240 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.759 0.241 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.759 0.241 0.000
S80-S89 Injuries to the knee and lower leg
0.759 0.241 0.000
C18 Malignant neoplasm of colon
0.757 0.243 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.756 0.244 0.000
O62 Abnormalities of forces of labour
0.756 0.244 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.756 0.244 0.000
S01.2 Open wound of nose
0.756 0.244 0.000
J30 Vasomotor and allergic rhinitis
0.756 0.244 0.000
D12.9 Anus and anal canal
0.754 0.246 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.754 0.246 0.000
O66 Other obstructed labour
0.753 0.247 0.000
S05 Injury of eye and orbit
0.750 0.250 0.000
R47-R49 Symptoms and signs involving speech and voice
0.748 0.252 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.748 0.252 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.747 0.253 0.000
D48.1 Connective and other soft tissue
0.746 0.254 0.000
D37.3 Appendix
0.746 0.254 0.000
D48.0 Bone and articular cartilage
0.746 0.254 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.745 0.255 0.000
T87 Complications peculiar to reattachment and amputation
0.741 0.259 0.000
F33.9 Recurrent depressive disorder, unspecified
0.740 0.260 0.000
D37.5 Rectum
0.740 0.260 0.000
H66 Suppurative and unspecified otitis media
0.738 0.262 0.000
H72.0 Central perforation of tympanic membrane
0.737 0.263 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.735 0.265 0.000
F43 Reaction to severe stress, and adjustment disorders
0.735 0.265 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.735 0.265 0.000
D32 Benign neoplasm of meninges
0.734 0.266 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.734 0.266 0.000
D37.4 Colon
0.733 0.267 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.733 0.267 0.000
W00-W19 Falls
0.731 0.269 0.000
O73 Retained placenta and membranes, without haemorrhage
0.730 0.270 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.729 0.270 0.000
C09 Malignant neoplasm of tonsil
0.727 0.273 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.726 0.274 0.000
T42.4 Benzodiazepines
0.725 0.275 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.724 0.276 0.000
F80-F89 Disorders of psychological development
0.723 0.277 0.000
G91 Hydrocephalus
0.722 0.278 0.000
H65 Nonsuppurative otitis media
0.721 0.278 0.000
G93.8 Other specified disorders of brain
0.721 0.279 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.719 0.280 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.719 0.281 0.000
F60 Specific personality disorders
0.719 0.281 0.000
C73 Malignant neoplasm of thyroid gland
0.718 0.282 0.000
R47 Speech disturbances, not elsewhere classified
0.718 0.282 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D12.1 Appendix
0.717 0.283 0.000
F38 Other mood [affective] disorders
0.716 0.284 0.000
F34 Persistent mood [affective] disorders
0.716 0.284 0.000
F39 Unspecified mood [affective] disorder
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
D37.1 Stomach
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.716 0.284 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
T36 Poisoning by systemic antibiotics
0.716 0.284 0.000
D31 Benign neoplasm of eye and adnexa
0.715 0.285 0.000
D30 Benign neoplasm of urinary organs
0.715 0.285 0.000
D29 Benign neoplasm of male genital organs
0.715 0.285 0.000
D26 Other benign neoplasms of uterus
0.715 0.285 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.715 0.285 0.000
D19 Benign neoplasm of mesothelial tissue
0.715 0.285 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.715 0.285 0.000
D36 Benign neoplasm of other and unspecified sites
0.714 0.286 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.712 0.287 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.712 0.288 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.711 0.289 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.711 0.289 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.710 0.290 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.710 0.290 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.709 0.291 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.709 0.291 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.706 0.294 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.703 0.297 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.702 0.298 0.000
F31.8 Other bipolar affective disorders
0.701 0.299 0.000
F31.7 Bipolar affective disorder, currently in remission
0.701 0.299 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.701 0.299 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.701 0.299 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.701 0.299 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.701 0.299 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.701 0.299 0.000
D23.3 Skin of other and unspecified parts of face
0.701 0.299 0.000
X50-X57 Overexertion, travel and privation
0.701 0.299 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.700 0.300 0.000
J92 Pleural plaque
0.700 0.300 0.000
C18.0 Caecum
0.700 0.300 0.000
H81 Disorders of vestibular function
0.699 0.301 0.000
O85-O92 Complications predominantly related to the puerperium
0.698 0.302 0.000
T39.0 Salicylates
0.698 0.302 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.698 0.302 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.697 0.302 0.000
T88.4 Failed or difficult intubation
0.697 0.303 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.696 0.304 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.696 0.304 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.696 0.304 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.696 0.304 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.696 0.304 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.696 0.304 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.696 0.304 0.000
F11 Mental and behavioural disorders due to use of opioids
0.696 0.304 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.696 0.304 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.696 0.304 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.695 0.304 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.695 0.305 0.000
F20.0 Paranoid schizophrenia
0.695 0.305 0.000
F10.2 Dependence syndrome
0.694 0.306 0.000
T79-T79 Certain early complications of trauma
0.693 0.307 0.000
F29 Unspecified nonorganic psychosis
0.693 0.307 0.000
G36 Other acute disseminated demyelination
0.693 0.307 0.000
O63 Long labour
0.692 0.308 0.000
S08 Traumatic amputation of part of head
0.692 0.308 0.000
S07 Crushing injury of head
0.692 0.308 0.000
S04 Injury of cranial nerves
0.692 0.308 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.692 0.308 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.691 0.309 0.000
C16 Malignant neoplasm of stomach
0.691 0.309 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.690 0.310 0.000
F17.1 Harmful use
0.690 0.310 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.689 0.310 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.689 0.310 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.689 0.310 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.689 0.310 0.000
O74 Complications of anaesthesia during labour and delivery
0.689 0.311 0.000
O71 Other obstetric trauma
0.689 0.311 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.689 0.311 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.689 0.311 0.000
O61 Failed induction of labour
0.689 0.311 0.000
O60 Preterm delivery
0.689 0.311 0.000
C20 Malignant neoplasm of rectum
0.688 0.312 0.000
F32.8 Other depressive episodes
0.687 0.313 0.000
H69 Other disorders of Eustachian tube
0.687 0.313 0.000
O70.9 Perineal laceration during delivery, unspecified
0.687 0.313 0.000
C10 Malignant neoplasm of oropharynx
0.687 0.313 0.000
F41 Other anxiety disorders
0.687 0.313 0.000
D11 Benign neoplasm of major salivary glands
0.684 0.316 0.000
F32.1 Moderate depressive episode
0.684 0.316 0.000
D48.5 Skin
0.683 0.316 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.683 0.317 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.683 0.317 0.000
T39.4 Antirheumatics, not elsewhere classified
0.683 0.317 0.000
T39.2 Pyrazolone derivatives
0.683 0.317 0.000
G20-G26 Extrapyramidal and movement disorders
0.682 0.317 0.000
T92 Sequelae of injuries of upper limb
0.682 0.318 0.000
R11 Nausea and vomiting
0.681 0.319 0.000
S01.4 Open wound of cheek and temporomandibular area
0.681 0.319 0.000
O70.2 Third degree perineal laceration during delivery
0.680 0.320 0.000
O72 Postpartum haemorrhage
0.680 0.320 0.000
T50.8 Diagnostic agents
0.680 0.320 0.000
T50.7 Analeptics and opioid receptor antagonists
0.680 0.320 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.680 0.320 0.000
T50.5 Appetite depressants
0.680 0.320 0.000
T50.4 Drugs affecting uric acid metabolism
0.680 0.320 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.680 0.320 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.680 0.320 0.000
T50.1 Loop [high-ceiling] diuretics
0.680 0.320 0.000
T50.0 Mineralocorticoids and their antagonists
0.680 0.320 0.000
J33.8 Other polyp of sinus
0.680 0.320 0.000
V80-V89 Other land transport accidents
0.679 0.321 0.000
G40-G47 Episodic and paroxysmal disorders
0.679 0.321 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.679 0.321 0.000
S01.9 Open wound of head, part unspecified
0.678 0.322 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.677 0.323 0.000
Y35-Y36 Legal intervention and operations of war
0.677 0.323 0.000
Y10-Y34 Event of undetermined intent
0.677 0.323 0.000
Y00-Y09 Assault
0.677 0.323 0.000
X85-X99 Assault
0.677 0.323 0.000
X30-X39 Exposure to forces of nature
0.677 0.323 0.000
X20-X29 Contact with venomous animals and plants
0.677 0.323 0.000
X10-X19 Contact with heat and hot substances
0.677 0.323 0.000
X00-X09 Exposure to smoke, fire and flames
0.677 0.323 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.677 0.323 0.000
W75-W84 Other accidental threats to breathing
0.677 0.323 0.000
W65-W74 Accidental drowning and submersion
0.677 0.323 0.000
W50-W64 Exposure to animate mechanical forces
0.677 0.323 0.000
V98-V99 Other and unspecified transport accidents
0.677 0.323 0.000
V95-V97 Air and space transport accidents
0.677 0.323 0.000
V90-V94 Water transport accidents
0.677 0.323 0.000
V70-V79 Bus occupant injured in transport accident
0.677 0.323 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.677 0.323 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.677 0.323 0.000
V40-V49 Car occupant injured in transport accident
0.677 0.323 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.677 0.323 0.000
V01-V09 Pedestrian injured in transport accident
0.677 0.323 0.000
F10.9 Unspecified mental and behavioural disorder
0.676 0.323 0.000
F10.8 Other mental and behavioural disorders
0.676 0.323 0.000
F10.7 Residual and late-onset psychotic disorder
0.676 0.323 0.000
F10.6 Amnesic syndrome
0.676 0.323 0.000
F10.5 Psychotic disorder
0.676 0.323 0.000
F10.4 Withdrawal state with delirium
0.676 0.323 0.000
J94 Other pleural conditions
0.677 0.323 0.000
H71 Cholesteatoma of middle ear
0.676 0.324 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.674 0.326 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.674 0.326 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.674 0.326 0.000
T42.3 Barbiturates
0.674 0.326 0.000
T42.2 Succinimides and oxazolidinediones
0.674 0.326 0.000
T42.1 Iminostilbenes
0.674 0.326 0.000
T42.0 Hydantoin derivatives
0.674 0.326 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.674 0.326 0.000
O75.8 Other specified complications of labour and delivery
0.674 0.326 0.000
S01.1 Open wound of eyelid and periocular area
0.673 0.327 0.000
F32.0 Mild depressive episode
0.672 0.327 0.000
F25 Schizoaffective disorders
0.672 0.328 0.000
J09-J18 Influenza and pneumonia
0.672 0.328 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.671 0.329 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.670 0.330 0.000
G93.9 Disorder of brain, unspecified
0.669 0.331 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.669 0.331 0.000
Y95 Nosocomial condition
0.668 0.332 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.667 0.333 0.000
S06 Intracranial injury
0.667 0.333 0.000
C92 Myeloid leukaemia
0.667 0.333 0.000
O70.3 Fourth degree perineal laceration during delivery
0.666 0.334 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.666 0.334 0.000
S01.0 Open wound of scalp
0.666 0.334 0.000
F22 Persistent delusional disorders
0.665 0.335 0.000
S80 Superficial injury of lower leg
0.665 0.335 0.000
S02.2 Fracture of nasal bones
0.665 0.335 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.665 0.335 0.000
S31 Open wound of abdomen, lower back and pelvis
0.665 0.335 0.000
F33.8 Other recurrent depressive disorders
0.663 0.337 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.663 0.337 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.663 0.337 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.662 0.338 0.000
H74.4 Polyp of middle ear
0.661 0.339 0.000
Q80-Q89 Other congenital malformations
0.661 0.339 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.660 0.340 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.660 0.340 0.000
G90 Disorders of autonomic nervous system
0.660 0.340 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.660 0.340 0.000
G92 Toxic encephalopathy
0.660 0.340 0.000
S00.1 Contusion of eyelid and periocular area
0.659 0.341 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.658 0.342 0.000
H70 Mastoiditis and related conditions
0.658 0.342 0.000
H68 Eustachian salpingitis and obstruction
0.658 0.342 0.000
H67 Otitis media in diseases classified elsewhere
0.658 0.342 0.000
Y44 Agents primarily affecting blood constituents
0.658 0.342 0.000
D12.7 Rectosigmoid junction
0.658 0.342 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.657 0.343 0.000
V10-V19 Pedal cyclist injured in transport accident
0.657 0.343 0.000
S40-S49 Injuries to the shoulder and upper arm
0.656 0.344 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.656 0.344 0.000
G96.0 Cerebrospinal fluid leak
0.655 0.345 0.000
O42.9 Premature rupture of membranes, unspecified
0.654 0.346 0.000
G81 Hemiplegia
0.653 0.346 0.000
F01 Vascular dementia
0.653 0.347 0.000
S01.7 Multiple open wounds of head
0.652 0.348 0.000
S79 Other and unspecified injuries of hip and thigh
0.652 0.348 0.000
R50-R69 General symptoms and signs
0.651 0.349 0.000
O36 Maternal care for other known or suspected foetal problems
0.650 0.350 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.650 0.350 0.000
G37 Other demyelinating diseases of central nervous system
0.650 0.350 0.000
J30.1 Allergic rhinitis due to pollen
0.650 0.350 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.649 0.351 0.000
F99-F99 Unspecified mental disorder
0.648 0.351 0.000
R47.1 Dysarthria and anarthria
0.648 0.352 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.647 0.353 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.647 0.353 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.647 0.353 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.647 0.353 0.000
D10.1 Tongue
0.646 0.354 0.000
F45 Somatoform disorders
0.645 0.354 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.645 0.355 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.645 0.355 0.000
C21 Malignant neoplasm of anus and anal canal
0.645 0.355 0.000
F23 Acute and transient psychotic disorders
0.644 0.356 0.000
F28 Other nonorganic psychotic disorders
0.644 0.356 0.000
F24 Induced delusional disorder
0.644 0.356 0.000
F21 Schizotypal disorder
0.644 0.356 0.000
T88.9 Complication of surgical and medical care, unspecified
0.644 0.356 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.644 0.356 0.000
T88.3 Malignant hyperthermia due to anaesthesis
0.644 0.356 0.000
T88.2 Shock due to anaesthesia
0.644 0.356 0.000
T88.1 Other complications following immunisation, not elsewhere classified
0.644 0.356 0.000
T88.0 Infection following immunisation
0.644 0.356 0.000
C25 Malignant neoplasm of pancreas
0.643 0.357 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.643 0.357 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.641 0.359 0.000
G30-G32 Other degenerative diseases of the nervous system
0.641 0.359 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.640 0.360 0.000
D37.9 Digestive organ, unspecified
0.640 0.360 0.000
D37.6 Liver, gallbladder and bile ducts
0.640 0.360 0.000
D37.2 Small intestine
0.640 0.360 0.000
D37.0 Lip, oral cavity and pharynx
0.640 0.360 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.639 0.361 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.639 0.361 0.000
S20 Superficial injury of thorax
0.639 0.361 0.000
U80 Agent resistant to penicillin and related antibiotics
0.638 0.362 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.638 0.362 0.000
O62.3 Precipitate labour
0.637 0.363 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.635 0.365 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.635 0.365 0.000
D45 Polycythaemia vera
0.635 0.365 0.000
J37 Chronic laryngitis and laryngotracheitis
0.634 0.366 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.633 0.367 0.000
C17 Malignant neoplasm of small intestine
0.633 0.367 0.000
C23 Malignant neoplasm of gallbladder
0.633 0.367 0.000
S99 Other and unspecified injuries of ankle and foot
0.633 0.367 0.000
J33.9 Nasal polyp, unspecified
0.633 0.367 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.632 0.368 0.000
C13 Malignant neoplasm of hypopharynx
0.632 0.368 0.000
C11 Malignant neoplasm of nasopharynx
0.632 0.368 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.632 0.368 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.632 0.368 0.000
C05 Malignant neoplasm of palate
0.632 0.368 0.000
C04 Malignant neoplasm of floor of mouth
0.632 0.368 0.000
C03 Malignant neoplasm of gum
0.632 0.368 0.000
C00 Malignant neoplasm of lip
0.632 0.368 0.000
C12 Malignant neoplasm of pyriform sinus
0.632 0.368 0.000
C07 Malignant neoplasm of parotid gland
0.632 0.368 0.000
C01 Malignant neoplasm of base of tongue
0.632 0.368 0.000
H81.0 Meniere's disease
0.632 0.368 0.000
R60 Oedema, not elsewhere classified
0.632 0.368 0.000
O43 Placental disorders
0.632 0.368 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.631 0.369 0.000
D48.7 Other specified sites
0.631 0.369 0.000
D48.4 Peritoneum
0.631 0.369 0.000
D48.3 Retroperitoneum
0.631 0.369 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.631 0.369 0.000
J36 Peritonsillar abscess
0.630 0.370 0.000
V20-V29 Motorcycle rider injured in transport accident
0.629 0.370 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.629 0.371 0.000
J32.0 Chronic maxillary sinusitis
0.629 0.371 0.000
D23.4 Skin of scalp and neck
0.628 0.372 0.000
F43.2 Adjustment disorders
0.628 0.372 0.000
S09 Other and unspecified injuries of head
0.627 0.373 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.627 0.373 0.000
D48.6 Breast
0.627 0.373 0.000
S72 Fracture of femur
0.627 0.373 0.000
Y83.0 Surgical operation with transplant of whole organ
0.627 0.373 0.000
S52 Fracture of forearm
0.625 0.375 0.000
R47.8 Other and unspecified speech disturbances
0.625 0.375 0.000
J32.8 Other chronic sinusitis
0.625 0.375 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.624 0.376 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.624 0.376 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.624 0.376 0.000
O44 Placenta praevia
0.623 0.377 0.000
J92.9 Pleural plaque without asbestos
0.622 0.377 0.000
J35 Chronic diseases of tonsils and adenoids
0.622 0.378 0.000
O40 Polyhydramnios
0.622 0.378 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.622 0.378 0.000
X59 Exposure to unspecified factor
0.622 0.378 0.000
J60-J70 Lung diseases due to external agents
0.621 0.378 0.000
S29 Other and unspecified injuries of thorax
0.621 0.379 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.620 0.379 0.000
Y83.3 Surgical operation with formation of external stoma
0.620 0.380 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.620 0.380 0.000
H74.0 Tympanosclerosis
0.620 0.380 0.000
D16.4 Bones of skull and face
0.620 0.380 0.000
T45.0 Antiallergic and antiemetic drugs
0.620 0.380 0.000
T90 Sequelae of injuries of head
0.620 0.380 0.000
J95-J99 Other diseases of the respiratory system
0.618 0.382 0.000
C81 Hodgkin's disease
0.618 0.382 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.617 0.383 0.000
J20-J22 Other acute lower respiratory infections
0.617 0.383 0.000
C09.9 Tonsil, unspecified
0.617 0.383 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.616 0.384 0.000
R69 Unknown and unspecified causes of morbidity
0.616 0.384 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.616 0.384 0.000
R60.0 Localised oedema
0.616 0.384 0.000
C18.2 Ascending colon
0.615 0.385 0.000
F30.9 Manic episode, unspecified
0.614 0.386 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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