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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17080102
log Bayes Factor = 7.48577
Chromosome 6   position 151,004,770  (GRCh37) Explore rs17080102 on Ensembl!
Variant rs17080102 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.113 0.887
I11 Hypertensive heart disease
0.000 0.231 0.769
I20-I25 Ischaemic heart diseases
0.000 0.277 0.723
I25 Chronic ischaemic heart disease
0.000 0.288 0.712
Chapter IX Diseases of the circulatory system
0.000 0.290 0.710
I24 Other acute ischaemic heart diseases
0.000 0.293 0.707
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.299 0.701
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.307 0.693
I12 Hypertensive renal disease
0.000 0.309 0.691
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.315 0.685
I21 Acute myocardial infarction
0.000 0.319 0.681
I25.1 Atherosclerotic heart disease
0.000 0.362 0.638
I13 Hypertensive heart and renal disease
0.000 0.364 0.636
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.374 0.626
I60-I69 Cerebrovascular diseases
0.000 0.395 0.605
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.403 0.597
I15 Secondary hypertension
0.000 0.427 0.573
I24.8 Other forms of acute ischaemic heart disease
0.000 0.434 0.566
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.434 0.566
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.448 0.552
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.448 0.552
I67 Other cerebrovascular diseases
0.000 0.454 0.546
I12.0 Hypertensive renal disease with renal failure
0.000 0.463 0.537
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.471 0.529
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.471 0.529
I23 Certain current complications following acute myocardial infarction
0.000 0.481 0.518
I25.2 Old myocardial infarction
0.000 0.484 0.516
I25.4 Coronary artery aneurysm
0.000 0.487 0.513
I12.9 Hypertensive renal disease without renal failure
0.000 0.488 0.512
I25.6 Silent myocardial ischaemia
0.000 0.489 0.511
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.489 0.511
I00-I02 Acute rheumatic fever
0.000 0.491 0.509
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.504 0.496
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.511 0.489
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.513 0.487
I67.8 Other specified cerebrovascular diseases
0.000 0.514 0.486
I65.2 Occlusion and stenosis of carotid artery
0.000 0.526 0.474
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.544 0.456
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.544 0.456
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.544 0.456
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.544 0.456
I21.9 Acute myocardial infarction, unspecified
0.000 0.546 0.454
I63 Cerebral infarction
0.000 0.553 0.447
I67.1 Cerebral aneurysm, nonruptured
0.000 0.556 0.444
I05-I09 Chronic rheumatic heart diseases
0.000 0.559 0.441
I67.9 Cerebrovascular disease, unspecified
0.000 0.565 0.435
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.566 0.434
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.566 0.434
I25.5 Ischaemic cardiomyopathy
0.000 0.566 0.434
I24.1 Dressler's syndrome
0.000 0.572 0.428
I21.4 Acute subendocardial myocardial infarction
0.000 0.586 0.414
I22 Subsequent myocardial infarction
0.000 0.589 0.411
I15.9 Seconday hypertension, unspecified
0.000 0.589 0.411
I15.8 Other secondary hypertension
0.000 0.589 0.411
I15.2 Hypertension secondary to endocrine disorders
0.000 0.589 0.411
I15.0 Renovascular hypertension
0.000 0.589 0.411
I61 Intracerebral haemorrhage
0.000 0.593 0.407
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.599 0.400
I62 Other nontraumatic intracranial haemorrhage
0.000 0.599 0.401
I67.2 Cerebral atherosclerosis
0.000 0.600 0.400
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.609 0.391
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.609 0.391
I67.5 Moyamoya disease
0.000 0.609 0.391
I67.4 Hypertensive encephalopathy
0.000 0.609 0.391
I67.3 Progressive vascular leukoencephalopathy
0.000 0.609 0.391
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.615 0.385
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.621 0.379
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.621 0.379
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.621 0.379
I65.1 Occlusion and stenosis of basilar artery
0.000 0.621 0.379
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.621 0.379
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.623 0.377
I05 Rheumatic mitral valve diseases
0.000 0.626 0.374
I23.8 Other current complications following acute myocardial infarction
0.000 0.628 0.372
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.628 0.372
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.628 0.372
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.628 0.372
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.628 0.372
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.628 0.372
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.628 0.372
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.628 0.372
I02 Rheumatic chorea
0.000 0.635 0.365
I01 Rheumatic fever with heart involvement
0.000 0.635 0.365
I00 Rheumatic fever without mention of heart involvement
0.000 0.635 0.365
I15.1 Hypertension secondary to other renal disorders
0.000 0.652 0.348
I63.9 Cerebral infarction, unspecified
0.000 0.654 0.346
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.658 0.342
I63.8 Other cerebral infarction
0.000 0.665 0.335
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.667 0.333
I60 Subarachnoid haemorrhage
0.000 0.674 0.326
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.679 0.321
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.679 0.321
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.679 0.321
I20 Angina pectoris
0.000 0.682 0.318
I25.3 Aneurysm of heart
0.001 0.683 0.316
I09 Other rheumatic heart diseases
0.000 0.684 0.316
I06 Rheumatic aortic valve diseases
0.000 0.684 0.316
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.689 0.311
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.689 0.311
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.689 0.311
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.689 0.311
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.689 0.311
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.689 0.311
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.689 0.311
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.689 0.311
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.689 0.311
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.689 0.311
I68.0 Cerebral amyloid angiopathy
0.000 0.689 0.311
I22.8 Subsequent myocardial infarction of other sites
0.000 0.690 0.310
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.691 0.309
I05.9 Mitral valve disease, unspecified
0.000 0.691 0.309
I05.0 Mitral stenosis
0.000 0.699 0.301
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.703 0.296
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.704 0.296
I27 Other pulmonary heart diseases
0.001 0.704 0.295
I61.8 Other intracerebral haemorrhage
0.000 0.708 0.292
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.708 0.292
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.708 0.292
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.708 0.292
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.708 0.292
I07 Rheumatic tricuspid valve diseases
0.000 0.709 0.291
I05.2 Mitral stenosis with insufficiency
0.000 0.712 0.288
I28 Other diseases of pulmonary vessels
0.001 0.712 0.287
I62.1 Nontraumatic extradural haemorrhage
0.000 0.712 0.287
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.715 0.285
I20.0 Unstable angina
0.000 0.716 0.284
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.718 0.282
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.726 0.274
I05.8 Other mitral valve diseases
0.000 0.731 0.268
I69 Sequelae of cerebrovascular disease
0.000 0.732 0.268
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.733 0.267
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.737 0.262
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.738 0.262
I01.8 Other acute rheumatic heart disease
0.000 0.738 0.262
I01.2 Acute rheumatic myocarditis
0.000 0.738 0.262
I01.1 Acute rheumatic endocarditis
0.000 0.738 0.262
I01.0 Acute rheumatic pericarditis
0.000 0.738 0.262
I02.9 Rheumatic chorea without heart involvement
0.000 0.738 0.262
I02.0 Rheumatic chorea with heart involvement
0.000 0.738 0.262
I27.0 Primary pulmonary hypertension
0.000 0.739 0.261
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.743 0.257
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.751 0.249
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.751 0.249
I95 Hypotension
0.000 0.752 0.248
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.756 0.244
I99 Other and unspecified disorders of circulatory system
0.000 0.756 0.243
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.757 0.243
I05.1 Rheumatic mitral insufficiency
0.000 0.761 0.239
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.766 0.234
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.766 0.234
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.766 0.234
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.766 0.234
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.766 0.234
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.769 0.230
I95.1 Orthostatic hypotension
0.000 0.771 0.229
I72 Other aneurysm
0.000 0.771 0.229
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.773 0.227
I06.8 Other rheumatic aortic valve diseases
0.000 0.773 0.227
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.773 0.227
I06.1 Rheumatic aortic insufficiency
0.000 0.773 0.227
I06.0 Rheumatic aortic stenosis
0.000 0.773 0.227
I09.9 Rheumatic heart disease, unspecified
0.000 0.773 0.227
I09.8 Other specified rheumatic heart diseases
0.000 0.773 0.227
I09.2 Chronic rheumatic pericarditis
0.000 0.773 0.227
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.773 0.227
I09.0 Rheumatic myocarditis
0.000 0.773 0.227
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.777 0.222
I27.8 Other specified pulmonary heart diseases
0.001 0.788 0.212
I27.1 Kyphoscoliotic heart disease
0.001 0.788 0.212
I07.9 Tricuspid valve disease, unspecified
0.000 0.791 0.209
I07.8 Other tricuspid valve diseases
0.000 0.791 0.209
I07.2 Tricuspid stenosis with insufficiency
0.000 0.791 0.209
I07.0 Tricuspid stenosis
0.000 0.791 0.209
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.793 0.206
I28.8 Other specified diseases of pulmonary vessels
0.001 0.793 0.206
I28.1 Aneurysm of pulmonary artery
0.001 0.793 0.206
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.793 0.206
I70 Atherosclerosis
0.000 0.796 0.204
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.797 0.202
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.797 0.202
I72.4 Aneurysm of artery of lower extremity
0.000 0.799 0.201
I97.1 Other functional disturbances following cardiac surgery
0.000 0.799 0.200
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.807 0.192
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.808 0.192
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.812 0.188
I97.0 Postcardiotomy syndrome
0.000 0.812 0.188
I72.0 Aneurysm of carotid artery
0.000 0.814 0.186
I20.1 Angina pectoris with documented spasm
0.000 0.815 0.185
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.001 0.815 0.184
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.815 0.184
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.815 0.184
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.815 0.184
I98.0 Cardiovascular syphilis
0.000 0.815 0.184
I07.1 Tricuspid insufficiency
0.000 0.816 0.184
I78 Diseases of capillaries
0.000 0.818 0.182
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.820 0.180
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.820 0.179
I95.0 Idiopathic hypotension
0.000 0.822 0.178
I27.2 Other secondary pulmonary hypertension
0.000 0.822 0.178
I72.3 Aneurysm of iliac artery
0.000 0.824 0.176
I22.0 Subsequent myocardial infarction of anterior wall
0.001 0.825 0.174
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.828 0.172
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.831 0.169
I27.9 Pulmonary heart disease, unspecified
0.001 0.833 0.167
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.001 0.833 0.167
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.834 0.165
I72.8 Aneurysm of other specified arteries
0.000 0.835 0.165
I72.9 Aneurysm of unspecified site
0.000 0.836 0.164
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.836 0.164
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.836 0.164
I72.2 Aneurysm of renal artery
0.000 0.836 0.164
I72.1 Aneurysm of artery of upper extremity
0.000 0.836 0.164
I95.2 Hypotension due to drugs
0.000 0.836 0.164
I26 Pulmonary embolism
0.003 0.837 0.160
I95.8 Other hypotension
0.000 0.849 0.151
I70.0 Atherosclerosis of aorta
0.000 0.849 0.150
I70.9 Generalised and unspecified atherosclerosis
0.000 0.854 0.146
I70.8 Atherosclerosis of other arteries
0.000 0.854 0.146
I70.1 Atherosclerosis of renal artery
0.000 0.854 0.146
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.855 0.145
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.856 0.144
I08 Multiple valve diseases
0.000 0.862 0.138
I60.8 Other subarachnoid haemorrhage
0.001 0.863 0.136
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.867 0.133
I78.9 Disease of capillaries, unspecified
0.000 0.869 0.131
I78.8 Other diseases of capillaries
0.000 0.869 0.131
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.877 0.123
I79.1 Aortitis in diseases classified elsewhere
0.000 0.877 0.123
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.877 0.123
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.879 0.121
I78.1 Naevus, nonneoplastic
0.000 0.883 0.117
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.884 0.116
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.003 0.887 0.111
I77 Other disorders of arteries and arterioles
0.000 0.887 0.113
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.888 0.112
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.892 0.108
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.894 0.106
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.895 0.105
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.895 0.105
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.895 0.105
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.895 0.105
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.895 0.105
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.895 0.105
I20.8 Other forms of angina pectoris
0.000 0.895 0.105
I74 Arterial embolism and thrombosis
0.000 0.898 0.101
I08.9 Multiple valve disease, unspecified
0.000 0.901 0.099
I20.9 Angina pectoris, unspecified
0.000 0.901 0.099
I30-I52 Other forms of heart disease
0.000 0.904 0.096
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.906 0.094
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.908 0.092
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.092 0.908 0.000
D47.1 Chronic myeloproliferative disease
0.091 0.909 0.000
I42 Cardiomyopathy
0.000 0.911 0.089
D37-D48 Neoplasms of uncertain or unknown behaviour
0.086 0.914 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.086 0.914 0.000
I73 Other peripheral vascular diseases
0.000 0.914 0.086
I46 Cardiac arrest
0.000 0.914 0.085
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.084 0.916 0.000
I77.8 Other specified disorders of arteries and arterioles
0.000 0.916 0.084
I38 Endocarditis, valve unspecified
0.000 0.919 0.081
I77.5 Necrosis of artery
0.000 0.919 0.081
I77.4 Coeliac artery compression syndrome
0.000 0.919 0.081
I77.3 Arterial fibromuscular dysplasia
0.000 0.919 0.081
I77.0 Arteriovenous fistula, acquired
0.000 0.919 0.081
D46 Myelodysplastic syndromes
0.080 0.920 0.000
I49 Other cardiac arrhythmias
0.000 0.920 0.080
I42.9 Cardiomyopathy, unspecified
0.000 0.921 0.079
I46.0 Cardiac arrest with successful resuscitation
0.000 0.922 0.078
D37.4 Colon
0.078 0.922 0.000
I33 Acute and subacute endocarditis
0.000 0.924 0.076
I08.0 Disorders of both mitral and aortic valves
0.000 0.925 0.075
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.926 0.074
I74.8 Embolism and thrombosis of other arteries
0.000 0.927 0.073
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.927 0.073
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.927 0.073
I45 Other conduction disorders
0.000 0.927 0.073
D37.5 Rectum
0.073 0.927 0.000
I42.0 Dilated cardiomyopathy
0.000 0.927 0.073
D46.9 Myelodysplastic syndrome, unspecified
0.072 0.928 0.000
I49.1 Atrial premature depolarisation
0.000 0.929 0.071
I77.2 Rupture of artery
0.000 0.929 0.071
D47.4 Osteomyelofibrosis
0.071 0.929 0.000
I71 Aortic aneurysm and dissection
0.000 0.929 0.071
D45 Polycythaemia vera
0.071 0.929 0.000
D37.3 Appendix
0.070 0.930 0.000
I52 Other heart disorders in diseases classified elsewhere
0.000 0.931 0.069
I48 Atrial fibrillation and flutter
0.000 0.931 0.069
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.931 0.069
I41 Myocarditis in diseases classified elsewhere
0.000 0.931 0.069
I40 Acute myocarditis
0.000 0.931 0.069
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.931 0.069
I32 Pericarditis in diseases classified elsewhere
0.000 0.931 0.069
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.069 0.931 0.000
D46.7 Other myelodysplastic syndromes
0.068 0.931 0.000
D37.1 Stomach
0.068 0.932 0.000
I08.8 Other multiple valve diseases
0.000 0.932 0.067
I42.2 Other hypertrophic cardiomyopathy
0.000 0.933 0.067
I42.8 Other cardiomyopathies
0.000 0.933 0.067
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.934 0.066
I69.3 Sequelae of cerebral infarction
0.002 0.934 0.065
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.066 0.934 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.066 0.934 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.066 0.934 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.066 0.934 0.000
D37.9 Digestive organ, unspecified
0.066 0.934 0.000
I42.6 Alcoholic cardiomyopathy
0.000 0.935 0.065
I49.0 Ventricular fibrillation and flutter
0.000 0.935 0.065
I37 Pulmonary valve disorders
0.000 0.935 0.065
D47.2 Monoclonal gammopathy
0.064 0.936 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.936 0.064
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.936 0.064
I42.5 Other restrictive cardiomyopathy
0.000 0.936 0.064
I42.4 Endocardial fibroelastosis
0.000 0.936 0.064
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.936 0.064
I74.5 Embolism and thrombosis of iliac artery
0.000 0.936 0.063
I45.5 Other specified heart block
0.000 0.938 0.062
I49.9 Cardiac arrhythmia, unspecified
0.000 0.938 0.062
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.062 0.938 0.000
D37.2 Small intestine
0.062 0.938 0.000
I33.0 Acute and subacute infective endocarditis
0.000 0.938 0.062
I49.3 Ventricular premature depolarisation
0.000 0.938 0.062
I73.8 Other specified peripheral vascular diseases
0.000 0.938 0.062
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.938 0.062
I46.1 Sudden cardiac death, so described
0.000 0.938 0.061
I49.4 Other and unspecified premature depolarisation
0.000 0.939 0.061
I46.9 Cardiac arrest, unspecified
0.000 0.939 0.061
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.060 0.940 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.059 0.941 0.000
I36 Nonrheumatic tricuspid valve disorders
0.000 0.941 0.059
I35 Nonrheumatic aortic valve disorders
0.000 0.941 0.059
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.942 0.058
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.058 0.942 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.058 0.942 0.000
D46.4 Refractory anaemia, unspecified
0.058 0.942 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.058 0.942 0.000
D46.2 Refractory anaemia with excess of blasts
0.058 0.942 0.000
D46.1 Refractory anaemia with sideroblasts
0.058 0.942 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.058 0.942 0.000
I30 Acute pericarditis
0.000 0.942 0.058
I49.2 Junctional premature depolarisation
0.000 0.943 0.057
D37.6 Liver, gallbladder and bile ducts
0.057 0.943 0.000
D37.0 Lip, oral cavity and pharynx
0.056 0.944 0.000
D44.0 Thyroid gland
0.056 0.944 0.000
I33.9 Acute endocarditis, unspecified
0.000 0.945 0.055
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.946 0.054
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.054 0.946 0.000
I45.9 Conduction disorder, unspecified
0.000 0.946 0.054
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.054 0.946 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.054 0.946 0.000
I45.4 Nonspecific intraventricular block
0.000 0.947 0.052
I45.3 Trifascicular block
0.000 0.947 0.052
I45.0 Right fascicular block
0.000 0.947 0.052
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.052 0.948 0.000
I35.0 Aortic (valve) stenosis
0.000 0.948 0.052
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.948 0.052
I45.6 Preexcitation syndrome
0.000 0.948 0.051
I45.2 Bifascicular block
0.000 0.949 0.051
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.949 0.051
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.949 0.051
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.949 0.051
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.949 0.051
D37.7 Other digestive organs
0.050 0.949 0.000
I77.1 Stricture of artery
0.000 0.950 0.050
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.950 0.050
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.950 0.050
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.950 0.050
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.950 0.050
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.950 0.050
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.950 0.050
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.950 0.050
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.950 0.050
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.950 0.050
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.950 0.050
I40.9 Acute myocarditis, unspecified
0.000 0.950 0.050
I40.8 Other acute myocarditis
0.000 0.950 0.050
I40.1 Isolated myocarditis
0.000 0.950 0.050
I40.0 Infective myocarditis
0.000 0.950 0.050
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.950 0.050
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.950 0.050
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.950 0.050
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.950 0.050
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.950 0.050
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.950 0.050
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.950 0.050
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.950 0.050
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.950 0.050
I48.4 Atypical atrial flutter
0.000 0.950 0.050
I48.3 Typical atrial flutter
0.000 0.950 0.050
I48.2 Chronic atrial fibrillation
0.000 0.950 0.050
I48.1 Persistent atrial fibrillation
0.000 0.950 0.050
I48.0 Paroxysmal atrial fibrillation
0.000 0.950 0.050
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.950 0.050
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.950 0.050
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.950 0.050
I77.6 Arteritis, unspecified
0.000 0.950 0.050
D44.9 Endocrine gland, unspecified
0.049 0.951 0.000
D44.8 Pluriglandular involvement
0.049 0.951 0.000
D44.7 Aortic body and other paraganglia
0.049 0.951 0.000
D44.6 Carotid body
0.049 0.951 0.000
D44.5 Pineal gland
0.049 0.951 0.000
D44.4 Craniopharyngeal duct
0.049 0.951 0.000
D44.3 Pituitary gland
0.049 0.951 0.000
D44.2 Parathyroid gland
0.049 0.951 0.000
D44.1 Adrenal gland
0.049 0.951 0.000
D41.4 Bladder
0.049 0.951 0.000
I45.1 Other and unspecified right bundle-branch block
0.000 0.951 0.049
I45.8 Other specified conduction disorders
0.000 0.952 0.048
I37.9 Pulmonary valve disorder, unspecified
0.000 0.953 0.047
I37.8 Other pulmonary valve disorders
0.000 0.953 0.047
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.953 0.047
I37.0 Pulmonary valve stenosis
0.000 0.953 0.047
D42.9 Meninges, unspecified
0.044 0.955 0.000
D42.1 Spinal meninges
0.044 0.955 0.000
D42.0 Cerebral meninges
0.044 0.955 0.000
D48.0 Bone and articular cartilage
0.045 0.955 0.000
D41.9 Urinary organ, unspecified
0.043 0.957 0.000
D41.7 Other urinary organs
0.043 0.957 0.000
D41.3 Urethra
0.043 0.957 0.000
D41.2 Ureter
0.043 0.957 0.000
D41.1 Renal pelvis
0.043 0.957 0.000
D40.9 Male genital organ, unspecified
0.043 0.957 0.000
D40.7 Other male genital organs
0.043 0.957 0.000
D40.1 Testis
0.043 0.957 0.000
I71.0 Dissection of aorta [any part]
0.000 0.957 0.042
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.957 0.042
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.957 0.042
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.957 0.042
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.957 0.042
I37.1 Pulmonary valve insufficiency
0.000 0.957 0.042
I35.1 Aortic (valve) insufficiency
0.000 0.958 0.042
I31 Other diseases of pericardium
0.000 0.958 0.042
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.958 0.041
I30.8 Other forms of acute pericarditis
0.000 0.958 0.041
I30.1 Infective pericarditis
0.000 0.958 0.041
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.958 0.041
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.959 0.041
D40.0 Prostate
0.040 0.960 0.000
I51 Complications and ill-defined descriptions of heart disease
0.000 0.960 0.040
D48.7 Other specified sites
0.039 0.961 0.000
D39.9 Female genital organ, unspecified
0.039 0.961 0.000
D39.7 Other female genital organs
0.039 0.961 0.000
D39.2 Placenta
0.039 0.961 0.000
D39.0 Uterus
0.039 0.961 0.000
D43.0 Brain, supratentorial
0.039 0.961 0.000
D43.9 Central nervous system, unspecified
0.039 0.961 0.000
D43.7 Other parts of central nervous system
0.039 0.961 0.000
D43.4 Spinal cord
0.039 0.961 0.000
D43.3 Cranial nerves
0.039 0.961 0.000
D43.1 Brain, infratentorial
0.039 0.961 0.000
D38.6 Respiratory organ, unspecified
0.039 0.961 0.000
D38.5 Other respiratory organs
0.039 0.961 0.000
D38.4 Thymus
0.039 0.961 0.000
D38.3 Mediastinum
0.039 0.961 0.000
D38.2 Pleura
0.039 0.961 0.000
D38.0 Larynx
0.039 0.961 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.038 0.962 0.000
D48.4 Peritoneum
0.038 0.962 0.000
D48.3 Retroperitoneum
0.038 0.962 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.038 0.962 0.000
I49.5 Sick sinus syndrome
0.000 0.962 0.037
I47 Paroxysmal tachycardia
0.000 0.963 0.037
D48.5 Skin
0.036 0.963 0.000
I34 Nonrheumatic mitral valve disorders
0.000 0.963 0.036
I35.9 Aortic valve disorder, unspecified
0.000 0.964 0.036
I95.9 Hypotension, unspecified
0.000 0.964 0.036
I73.0 Raynaud's syndrome
0.000 0.965 0.035
I35.8 Other aortic valve disorders
0.000 0.966 0.034
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.967 0.032
I49.8 Other specified cardiac arrhythmias
0.000 0.968 0.032
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.032 0.968 0.000
D41.0 Kidney
0.031 0.969 0.000
Y40 Systemic antibiotics
0.031 0.969 0.000
I51.4 Myocarditis, unspecified
0.000 0.969 0.031
D39.1 Ovary
0.031 0.969 0.000
D38.1 Trachea, bronchus and lung
0.030 0.969 0.000
D43.2 Brain, unspecified
0.030 0.969 0.000
I31.8 Other specified diseases of pericardium
0.000 0.970 0.030
I31.2 Haemopericardium, not elsewhere classified
0.000 0.970 0.030
I31.1 Chronic constrictive pericarditis
0.000 0.970 0.030
I31.0 Chronic adhesive pericarditis
0.000 0.970 0.030
Y40.0 Penicillins
0.030 0.970 0.000
I30.9 Acute pericarditis, unspecified
0.000 0.970 0.030
I73.9 Peripheral vascular disease, unspecified
0.000 0.971 0.029
I51.0 Cardiac septal defect, acquired
0.000 0.971 0.029
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.029 0.971 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.971 0.029
I51.5 Myocardial degeneration
0.000 0.971 0.029
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.971 0.029
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.971 0.029
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.971 0.029
Y51 Drugs primarily affecting the autonomic nervous system
0.028 0.972 0.000
D48.6 Breast
0.028 0.972 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.001 0.972 0.027
Y43 Primarily systemic agents
0.027 0.973 0.000
Y54.3 Benzothiadiazine derivatives
0.027 0.973 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.974 0.026
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.974 0.026
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.974 0.026
I47.0 Reentry ventricular arrhythmia
0.000 0.974 0.026

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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