TreeWAS – Variant ID: rs17111652

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20.9 Angina pectoris, unspecified	0.086	0.914	0.000
I20 Angina pectoris	0.056	0.944	0.000
I20.8 Other forms of angina pectoris	0.050	0.950	0.000
I20.1 Angina pectoris with documented spasm	0.040	0.959	0.000
I20.0 Unstable angina	0.039	0.961	0.000
I77 Other disorders of arteries and arterioles	0.016	0.984	0.000
I77.6 Arteritis, unspecified	0.016	0.984	0.000
I77.1 Stricture of artery	0.015	0.985	0.000
N18.3 Chronic kidney disease, stage 3	0.014	0.986	0.000
K63.5 Polyp of colon	0.014	0.986	0.000
I77.0 Arteriovenous fistula, acquired	0.014	0.986	0.000
I77.8 Other specified disorders of arteries and arterioles	0.013	0.987	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.013	0.987	0.000
I71 Aortic aneurysm and dissection	0.013	0.987	0.000
I72 Other aneurysm	0.012	0.988	0.000
K63.9 Disease of intestine, unspecified	0.012	0.988	0.000
K63 Other diseases of intestine	0.012	0.988	0.000
I77.5 Necrosis of artery	0.012	0.988	0.000
I77.4 Coeliac artery compression syndrome	0.012	0.988	0.000
I77.3 Arterial fibromuscular dysplasia	0.012	0.988	0.000
I77.2 Rupture of artery	0.012	0.988	0.000
Z48.8 Other specified surgical follow-up care	0.012	0.988	0.000
I72.4 Aneurysm of artery of lower extremity	0.012	0.988	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.011	0.989	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.011	0.989	0.000
I20-I25 Ischaemic heart diseases	0.011	0.989	0.000
I71.0 Dissection of aorta [any part]	0.011	0.989	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.010	0.989	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.010	0.990	0.000
K63.2 Fistula of intestine	0.010	0.990	0.000
K63.4 Enteroptosis	0.010	0.990	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.990	0.010
N18 Chronic renal failure	0.010	0.990	0.000
Z50.1 Other physical therapy	0.000	0.990	0.010
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.009	0.990	0.000
I72.0 Aneurysm of carotid artery	0.009	0.991	0.000
N18.2 Chronic kidney disease, stage 2	0.009	0.991	0.000
I72.3 Aneurysm of iliac artery	0.009	0.991	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.009	0.991	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.009	0.991	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.009	0.991	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.009	0.991	0.000
Z50 Care involving use of rehabilitation procedures	0.000	0.991	0.009
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.991	0.009
K63.0 Abscess of intestine	0.009	0.991	0.000
I72.9 Aneurysm of unspecified site	0.009	0.991	0.000
I72.8 Aneurysm of other specified arteries	0.009	0.991	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.009	0.991	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.009	0.991	0.000
I72.2 Aneurysm of renal artery	0.009	0.991	0.000
I72.1 Aneurysm of artery of upper extremity	0.009	0.991	0.000
K63.8 Other specified diseases of intestine	0.009	0.991	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.991	0.009
I70 Atherosclerosis	0.008	0.991	0.000
I24 Other acute ischaemic heart diseases	0.008	0.992	0.000
Z50.5 Speech therapy	0.000	0.992	0.008
I74 Arterial embolism and thrombosis	0.008	0.992	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.008	0.992	0.000
K63.3 Ulcer of intestine	0.008	0.992	0.000
N18.0 End-stage renal disease	0.008	0.992	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.008	0.992	0.000
I23 Certain current complications following acute myocardial infarction	0.008	0.992	0.000
Z48.0 Attention to surgical dressings and sutures	0.008	0.992	0.000
I73 Other peripheral vascular diseases	0.008	0.992	0.000
I22 Subsequent myocardial infarction	0.008	0.992	0.000
N18.9 Chronic renal failure, unspecified	0.008	0.992	0.000
I87 Other disorders of veins	0.008	0.992	0.000
K63.1 Perforation of intestine (nontraumatic)	0.008	0.992	0.000
I78 Diseases of capillaries	0.008	0.992	0.000
Z48 Other surgical follow-up care	0.008	0.992	0.000
I87.1 Compression of vein	0.007	0.993	0.000
N18.8 Other chronic renal failure	0.007	0.993	0.000
N18.1 Chronic kidney disease, stage 1	0.007	0.993	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.007	0.993	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.007	0.993	0.000
I79.1 Aortitis in diseases classified elsewhere	0.007	0.993	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.007	0.993	0.000
Z50.2 Alcohol rehabilitation	0.000	0.993	0.007
I24.9 Acute ischaemic heart disease, unspecified	0.007	0.993	0.000
Z50.4 Psychotherapy, not elsewhere classified	0.000	0.993	0.007
R79.8 Other specified abnormal findings of blood chemistry	0.007	0.993	0.000
I87.8 Other specified disorders of veins	0.007	0.993	0.000
Z50.6 Orthoptic training	0.000	0.993	0.007
Z50.3 Drug rehabilitation	0.000	0.993	0.007
N18.5 Chronic kidney disease, stage 5	0.007	0.993	0.000
I24.8 Other forms of acute ischaemic heart disease	0.007	0.993	0.000
I22.8 Subsequent myocardial infarction of other sites	0.007	0.993	0.000
Z50.8 Care involving use of rehabilitation procedures	0.000	0.993	0.007
I70.9 Generalised and unspecified atherosclerosis	0.006	0.994	0.000
I70.8 Atherosclerosis of other arteries	0.006	0.994	0.000
I70.1 Atherosclerosis of renal artery	0.006	0.994	0.000
I24.1 Dressler's syndrome	0.006	0.994	0.000
I70.0 Atherosclerosis of aorta	0.006	0.994	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.006	0.994	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.006	0.994	0.000
I74.8 Embolism and thrombosis of other arteries	0.006	0.994	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.006	0.994	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.006	0.994	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.006	0.994	0.000
I74.5 Embolism and thrombosis of iliac artery	0.006	0.994	0.000
I23.8 Other current complications following acute myocardial infarction	0.006	0.994	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.006	0.994	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.006	0.994	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.006	0.994	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.006	0.994	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.006	0.994	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.006	0.994	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.006	0.994	0.000
I73.8 Other specified peripheral vascular diseases	0.006	0.994	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.006	0.994	0.000
Chapter IX Diseases of the circulatory system	0.006	0.994	0.000
E78.0 Pure hypercholesterolaemia	0.006	0.994	0.000
I87.9 Disorder of vein, unspecified	0.006	0.994	0.000
I87.0 Postphlebitic syndrome	0.006	0.994	0.000
I78.9 Disease of capillaries, unspecified	0.006	0.994	0.000
I78.8 Other diseases of capillaries	0.006	0.994	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.006	0.994	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.005	0.994	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.006	0.994	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.006	0.994	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.005	0.994	0.000
I85 Oesophageal varices	0.006	0.994	0.000
I73.9 Peripheral vascular disease, unspecified	0.006	0.994	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.005	0.994	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.005	0.994	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.005	0.995	0.000
I86 Varicose veins of other sites	0.005	0.995	0.000
I85.9 Oesophageal varices without bleeding	0.005	0.995	0.000
Z50.0 Cardiac rehabilitation	0.000	0.995	0.005
Z98.8 Other specified postsurgical states	0.005	0.995	0.000
I85.0 Oesophageal varices with bleeding	0.005	0.995	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.005	0.995	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.005	0.995	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.005	0.995	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.005	0.995	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.005	0.995	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.005	0.995	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.005	0.995	0.000
E78.5 Hyperlipidaemia, unspecified	0.005	0.995	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.005	0.995	0.000
I73.0 Raynaud's syndrome	0.005	0.995	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.004	0.995	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.005	0.995	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.005	0.995	0.000
I00-I02 Acute rheumatic fever	0.004	0.995	0.000
I86.4 Gastric varices	0.004	0.995	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.004	0.995	0.000
I88 Nonspecific lymphadenitis	0.004	0.995	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.004	0.996	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.004	0.996	0.000
N18.4 Chronic kidney disease, stage 4	0.004	0.996	0.000
I78.1 Naevus, nonneoplastic	0.004	0.996	0.000
I81 Portal vein thrombosis	0.004	0.996	0.000
I86.8 Varicose veins of other specified sites	0.004	0.996	0.000
I82 Other venous embolism and thrombosis	0.004	0.996	0.000
I89.1 Lymphangitis	0.004	0.996	0.000
I86.3 Vulval varices	0.004	0.996	0.000
I86.2 Pelvic varices	0.004	0.996	0.000
I86.0 Sublingual varices	0.004	0.996	0.000
I25 Chronic ischaemic heart disease	0.004	0.996	0.000
I80 Phlebitis and thrombophlebitis	0.004	0.996	0.000
E78.4 Other hyperlipidaemia	0.004	0.996	0.000
I26 Pulmonary embolism	0.004	0.996	0.000
I82.2 Embolism and thrombosis of vena cava	0.004	0.996	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.003	0.996	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.004	0.996	0.000
I28 Other diseases of pulmonary vessels	0.003	0.996	0.000
I86.1 Scrotal varices	0.003	0.996	0.000
Z48.9 Surgical follow-up care, unspecified	0.003	0.996	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.003	0.996	0.000
I02 Rheumatic chorea	0.003	0.996	0.000
I01 Rheumatic fever with heart involvement	0.003	0.996	0.000
I00 Rheumatic fever without mention of heart involvement	0.003	0.996	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.003	0.996	0.000
I88.8 Other nonspecific lymphadenitis	0.003	0.996	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.003	0.996	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.003	0.996	0.000
I27 Other pulmonary heart diseases	0.003	0.997	0.000
E78.6 Lipoprotein deficiency	0.003	0.997	0.000
E78.3 Hyperchylomicronaemia	0.003	0.997	0.000
E78.1 Pure hyperglyceridaemia	0.003	0.997	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.003	0.997	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.003	0.997	0.000
E78.2 Mixed hyperlipidaemia	0.003	0.997	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.003	0.997	0.000
I89.0 Lymphoedema, not elsewhere classified	0.003	0.997	0.000
Z98.1 Arthrodesis status	0.003	0.997	0.000
F17.1 Harmful use	0.000	0.997	0.003
I82.3 Embolism and thrombosis of renal vein	0.003	0.997	0.000
I82.1 Thrombophlebitis migrans	0.003	0.997	0.000
I82.0 Budd-Chiari syndrome	0.003	0.997	0.000
E78.8 Other disorders of lipoprotein metabolism	0.003	0.997	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.003	0.997	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.003	0.997	0.000
I25.6 Silent myocardial ischaemia	0.003	0.997	0.000
I25.4 Coronary artery aneurysm	0.003	0.997	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.003	0.997	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.003	0.997	0.000
Z98 Other postsurgical states	0.003	0.997	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.003	0.997	0.000
I25.5 Ischaemic cardiomyopathy	0.003	0.997	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.003	0.997	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.003	0.997	0.000
I28.8 Other specified diseases of pulmonary vessels	0.003	0.997	0.000
I28.1 Aneurysm of pulmonary artery	0.003	0.997	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.003	0.997	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.003	0.997	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.003	0.997	0.000
I01.8 Other acute rheumatic heart disease	0.003	0.997	0.000
I01.2 Acute rheumatic myocarditis	0.003	0.997	0.000
I01.1 Acute rheumatic endocarditis	0.003	0.997	0.000
I01.0 Acute rheumatic pericarditis	0.003	0.997	0.000
I02.9 Rheumatic chorea without heart involvement	0.003	0.997	0.000
I02.0 Rheumatic chorea with heart involvement	0.003	0.997	0.000
I27.9 Pulmonary heart disease, unspecified	0.003	0.997	0.000
I27.2 Other secondary pulmonary hypertension	0.003	0.997	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.003	0.997	0.000
I27.8 Other specified pulmonary heart diseases	0.003	0.997	0.000
I27.1 Kyphoscoliotic heart disease	0.003	0.997	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.003	0.997	0.000
I25.3 Aneurysm of heart	0.003	0.997	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.003	0.997	0.000
I05-I09 Chronic rheumatic heart diseases	0.002	0.997	0.000
Z86.0 Personal history of other neoplasms	0.003	0.997	0.000
I99 Other and unspecified disorders of circulatory system	0.002	0.997	0.000
R79 Other abnormal findings of blood chemistry	0.002	0.997	0.000
I97.1 Other functional disturbances following cardiac surgery	0.002	0.997	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.998	0.002
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
Y60.0 During surgical operation	0.000	0.998	0.002
G45 Transient cerebral ischaemic attacks and related syndromes	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.002	0.998	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.002	0.998	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.998	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.002	0.998	0.000
I97.0 Postcardiotomy syndrome	0.002	0.998	0.000
Z98.0 Intestinal bypass and anastomosis status	0.002	0.998	0.000
R29.6 Tendency to fall, not elsewhere classified	0.000	0.998	0.002
F17.2 Dependence syndrome	0.000	0.998	0.002
I60-I69 Cerebrovascular diseases	0.002	0.998	0.000
C25.0 Head of pancreas	0.002	0.998	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.002	0.998	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.002	0.998	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I98.0 Cardiovascular syphilis	0.002	0.998	0.000
I09 Other rheumatic heart diseases	0.002	0.998	0.000
I06 Rheumatic aortic valve diseases	0.002	0.998	0.000
I83 Varicose veins of lower extremities	0.002	0.998	0.000
M54.39 Sciatica (Site unspecified)	0.002	0.998	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.002	0.998	0.000
I07 Rheumatic tricuspid valve diseases	0.002	0.998	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.002	0.998	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.002	0.998	0.000
K04.5 Chronic apical periodontitis	0.002	0.998	0.000
M34.1 CR(E)ST syndrome	0.002	0.998	0.000
I69 Sequelae of cerebrovascular disease	0.002	0.998	0.000
J47 Bronchiectasis	0.000	0.998	0.002
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.002	0.998	0.000
I61 Intracerebral haemorrhage	0.002	0.998	0.000
F17.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F17.8 Other mental and behavioural disorders	0.000	0.998	0.002
F17.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F17.6 Amnesic syndrome	0.000	0.998	0.002
F17.5 Psychotic disorder	0.000	0.998	0.002
F17.4 Withdrawal state with delirium	0.000	0.998	0.002
F17.3 Withdrawal state	0.000	0.998	0.002
F17.0 Acute intoxication	0.000	0.998	0.002
M34.9 Systemic sclerosis, unspecified	0.002	0.998	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.002	0.998	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.002	0.998	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.002	0.998	0.000
G45.0 Vertebro-basilar artery syndrome	0.002	0.998	0.000
I63 Cerebral infarction	0.002	0.998	0.000
R03.1 Nonspecific low blood-pressure reading	0.002	0.998	0.000
I62 Other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.002	0.998	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.001	0.998	0.001
I10-I15 Hypertensive diseases	0.002	0.998	0.000
M34.8 Other forms of systemic sclerosis	0.002	0.998	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.002	0.998	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.002	0.998	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.002	0.998	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.001	0.998	0.000
I06.8 Other rheumatic aortic valve diseases	0.001	0.998	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.001	0.998	0.000
I06.1 Rheumatic aortic insufficiency	0.001	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.001	0.998	0.000
I09.9 Rheumatic heart disease, unspecified	0.001	0.998	0.000
I09.8 Other specified rheumatic heart diseases	0.001	0.998	0.000
I09.2 Chronic rheumatic pericarditis	0.001	0.998	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.001	0.998	0.000
I09.0 Rheumatic myocarditis	0.001	0.998	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.002	0.998	0.000
L40.9 Psoriasis, unspecified	0.000	0.998	0.002
R79.0 Abnormal level of blood mineral	0.002	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.002	0.998	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.002	0.998	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.002	0.998	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.002	0.998	0.000
M34 Systemic sclerosis	0.002	0.998	0.000
I07.9 Tricuspid valve disease, unspecified	0.001	0.998	0.000
I07.8 Other tricuspid valve diseases	0.001	0.998	0.000
I07.2 Tricuspid stenosis with insufficiency	0.001	0.998	0.000
I07.0 Tricuspid stenosis	0.001	0.998	0.000
G45.3 Amaurosis fugax	0.002	0.998	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.002	0.998	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.001	0.998	0.000
I61.8 Other intracerebral haemorrhage	0.002	0.998	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.002	0.998	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.002	0.998	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.002	0.998	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.002	0.998	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.002	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.002	0.998	0.000
I11 Hypertensive heart disease	0.002	0.998	0.000
D37.7 Other digestive organs	0.002	0.998	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.002	0.998	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.002	0.998	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.002	0.998	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.002	0.998	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.002	0.998	0.000
K83.1 Obstruction of bile duct	0.002	0.998	0.000
I62.1 Nontraumatic extradural haemorrhage	0.001	0.998	0.000
K83.0 Cholangitis	0.002	0.998	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.001	0.998	0.000
I05.8 Other mitral valve diseases	0.001	0.998	0.001
I05.2 Mitral stenosis with insufficiency	0.001	0.998	0.001
I05.1 Rheumatic mitral insufficiency	0.001	0.998	0.001
I13 Hypertensive heart and renal disease	0.001	0.998	0.000
G45.4 Transient global amnesia	0.001	0.998	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.001	0.998	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.001	0.998	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.001	0.998	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.001	0.998	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.001	0.998	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.001	0.998	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.001	0.998	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.001	0.998	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.001	0.998	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
I68.0 Cerebral amyloid angiopathy	0.001	0.998	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.002	0.998	0.000
I15 Secondary hypertension	0.001	0.998	0.000
M54.36 Sciatica (Lumbar region)	0.002	0.998	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.001	0.998	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.001	0.998	0.000
M34.0 Progressive systemic sclerosis	0.001	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.002	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.001	0.998	0.000
I05.0 Mitral stenosis	0.001	0.998	0.001
I63.8 Other cerebral infarction	0.001	0.998	0.000
W29.9 Unspecified place	0.000	0.998	0.001
I61.9 Intracerebral haemorrhage, unspecified	0.001	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.001	0.998	0.000
N30.9 Cystitis, unspecified	0.002	0.998	0.000
N17-N19 Renal failure	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.001	0.998	0.001
I11.0 Hypertensive heart disease with (congestive) heart failure	0.001	0.998	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.998	0.001
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.001	0.998	0.000
F41.9 Anxiety disorder, unspecified	0.000	0.998	0.001
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.001	0.999	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.001	0.999	0.000
F41.1 Generalised anxiety disorder	0.000	0.999	0.001
H26.9 Cataract, unspecified	0.001	0.999	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.001	0.999	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.001	0.999	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.001	0.999	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.001	0.999	0.000
I15.9 Seconday hypertension, unspecified	0.001	0.999	0.000
I15.8 Other secondary hypertension	0.001	0.999	0.000
I15.2 Hypertension secondary to endocrine disorders	0.001	0.999	0.000
I15.0 Renovascular hypertension	0.001	0.999	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.001	0.999	0.000
M54.3 Sciatica	0.001	0.999	0.000
F41 Other anxiety disorders	0.000	0.999	0.001
N72 Inflammatory disease of cervix uteri	0.000	0.999	0.001
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.000	0.999	0.001
F41.2 Mixed anxiety and depressive disorder	0.000	0.999	0.001
I95 Hypotension	0.001	0.999	0.000
I15.1 Hypertension secondary to other renal disorders	0.001	0.999	0.000
D35.2 Pituitary gland	0.001	0.999	0.000
R30.0 Dysuria	0.000	0.999	0.001
C25.9 Pancreas, unspecified	0.001	0.999	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.001	0.999	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.001	0.999	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.001	0.999	0.000
I65.1 Occlusion and stenosis of basilar artery	0.001	0.999	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.001	0.999	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.001	0.999	0.000
C25 Malignant neoplasm of pancreas	0.001	0.999	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.999	0.001
C22.1 Intrahepatic bile duct carcinoma	0.001	0.999	0.000
Z83.3 Family history of diabetes mellitus	0.000	0.999	0.001
K83 Other diseases of biliary tract	0.001	0.999	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.001	0.999	0.000
M24.1 Other articular cartilage disorders	0.001	0.999	0.000
Y60.9 During unspecified surgical and medical care	0.000	0.999	0.001
Y60.8 During other surgical and medical care	0.000	0.999	0.001
Y60.7 During administration of enema	0.000	0.999	0.001
Y60.6 During aspiration, puncture and other catheterisation	0.000	0.999	0.001
Y60.5 During heart catheterisation	0.000	0.999	0.001
Y60.4 During endoscopic examination	0.000	0.999	0.001
Y60.3 During injection or immunisation	0.000	0.999	0.001
Y60.2 During kidney dialysis or other perfusion	0.000	0.999	0.001
Y60.1 During infusion or transfusion	0.000	0.999	0.001
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M54.35 Sciatica (Thoracolumbar region)	0.001	0.999	0.000
M54.34 Sciatica-Thoracic	0.001	0.999	0.000
M54.33 Sciatica-Cervicothoracic	0.001	0.999	0.000
M54.32 Sciatica-Cervical	0.001	0.999	0.000
M54.31 Sciatica-Occipit-atl-axl	0.001	0.999	0.000
M54.30 Sciatica (Multiple sites in spine)	0.001	0.999	0.000
F41.8 Other specified anxiety disorders	0.000	0.999	0.001
F41.3 Other mixed anxiety disorders	0.000	0.999	0.001
I95.8 Other hypotension	0.001	0.999	0.000
I95.0 Idiopathic hypotension	0.001	0.999	0.000
M25.47 Effusion of joint (Ankle and foot)	0.001	0.999	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.001	0.999	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.001	0.999	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
I95.2 Hypotension due to drugs	0.001	0.999	0.000
M50.1 Cervical disk disorder with radiculopathy	0.001	0.999	0.000
S80.9 Superficial injury of lower leg, unspecified	0.001	0.999	0.000
I08 Multiple valve diseases	0.001	0.999	0.001
E61.1 Iron deficiency	0.001	0.999	0.000
I60 Subarachnoid haemorrhage	0.001	0.999	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.000	0.999	0.001
M24.11 Other articular cartilage disorders (Shoulder region)	0.001	0.999	0.000
M54.37 Sciatica (Lumbosacral region)	0.001	0.999	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.001	0.999	0.000
C25.8 Overlapping lesion of pancreas	0.001	0.999	0.000
C25.7 Other parts of pancreas	0.001	0.999	0.000
C25.4 Endocrine pancreas	0.001	0.999	0.000
C25.3 Pancreatic duct	0.001	0.999	0.000
C25.2 Tail of pancreas	0.001	0.999	0.000
C25.1 Body of pancreas	0.001	0.999	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.999	0.001
G43.9 Migraine, unspecified	0.001	0.999	0.000
K83.9 Disease of biliary tract, unspecified	0.001	0.999	0.000
K83.5 Biliary cyst	0.001	0.999	0.000
K83.4 Spasm of sphincter of Oddi	0.001	0.999	0.000
K83.3 Fistula of bile duct	0.001	0.999	0.000
K83.2 Perforation of bile duct	0.001	0.999	0.000
L40.5 Arthropathic psoriasis	0.000	0.999	0.001
M24.19 Other articular cartilage disorders (Site unspecified)	0.001	0.999	0.000
M24.18 Other articular cartilage disorders (Other)	0.001	0.999	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.001	0.999	0.000
M24.14 Other articular cartilage disorders (Hand)	0.001	0.999	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.001	0.999	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.001	0.999	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.001	0.999	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.001	0.999	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.001	0.999	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.001	0.999	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M25.06 Haemarthrosis (Lower leg)	0.001	0.999	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.999	0.001
F43.2 Adjustment disorders	0.000	0.999	0.001
I08.9 Multiple valve disease, unspecified	0.001	0.999	0.001
I08.2 Disorders of both aortic and tricuspid valves	0.001	0.999	0.001
S89.9 Unspecified injury of lower leg	0.001	0.999	0.000
Z96.0 Presence of urogenital implants	0.000	0.999	0.001
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.001	0.999	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.001	0.999	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.001	0.999	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.001	0.999	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.001	0.999	0.000
Z88.5 Personal history of allergy to narcotic agent	0.001	0.999	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.000	0.999	0.001
F18 Mental and behavioural disorders due to use of volatile solvents	0.000	0.999	0.001
F16 Mental and behavioural disorders due to use of hallucinogens	0.000	0.999	0.001
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.000	0.999	0.001
F14 Mental and behavioural disorders due to use of cocaine	0.000	0.999	0.001
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.000	0.999	0.001
F11 Mental and behavioural disorders due to use of opioids	0.000	0.999	0.001
G43.8 Other migraine	0.001	0.999	0.000
I60.8 Other subarachnoid haemorrhage	0.001	0.999	0.000
L40 Psoriasis	0.000	0.999	0.001
M25.37 Other instability of joint (Ankle and foot)	0.001	0.999	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.001	0.999	0.000
I08.8 Other multiple valve diseases	0.001	0.999	0.001
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.001	0.999	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.000	0.999	0.001
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.001	0.999	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.001	0.999	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.999	0.001
U89.8 Agent resistant to other single specified antibiotic	0.001	0.999	0.000
I67 Other cerebrovascular diseases	0.001	0.999	0.000
F11.9 Unspecified mental and behavioural disorder	0.000	0.999	0.001
F11.8 Other mental and behavioural disorders	0.000	0.999	0.001
F11.7 Residual and late-onset psychotic disorder	0.000	0.999	0.001
F11.6 Amnesic syndrome	0.000	0.999	0.001
F11.5 Psychotic disorder	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations