TreeWAS – Variant ID: rs1716403

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	0.753	0.247	0.000
E11 Non-insulin-dependent diabetes mellitus	0.750	0.250	0.000
E11.4 With neurological complications	0.738	0.262	0.000
E11.3 With ophthalmic complications	0.736	0.264	0.000
E11.5 With peripheral circulatory complications	0.658	0.342	0.000
E11.7 With multiple complications	0.585	0.415	0.000
E11.0 With coma	0.555	0.445	0.000
E11.6 With other specified complications	0.538	0.462	0.000
E11.8 With unspecified complications	0.444	0.555	0.000
E11.2 With renal complications	0.429	0.571	0.000
E11.1 With ketoacidosis	0.285	0.714	0.001
K83.8 Other specified diseases of biliary tract	0.000	0.819	0.181
E10-E14 Diabetes mellitus	0.085	0.915	0.000
E12 Malnutrition-related diabetes mellitus	0.061	0.939	0.000
E13 Other specified diabetes mellitus	0.045	0.954	0.000
E12.9 Without complications	0.044	0.956	0.000
E12.8 With unspecified complications	0.044	0.956	0.000
E12.7 With multiple complications	0.044	0.956	0.000
E12.6 With other specified complications	0.044	0.956	0.000
E12.5 With peripheral circulatory complications	0.044	0.956	0.000
E12.4 With neurological complications	0.044	0.956	0.000
E12.3 With ophthalmic complications	0.044	0.956	0.000
E12.2 With renal complications	0.044	0.956	0.000
E12.1 With ketoacidosis	0.044	0.956	0.000
E12.0 With coma	0.044	0.956	0.000
E10 Insulin-dependent diabetes mellitus	0.042	0.958	0.000
E14 Unspecified diabetes mellitus	0.040	0.960	0.000
E10.3 With ophthalmic complications	0.037	0.963	0.000
E10.9 Without complications	0.034	0.966	0.000
E10.8 With unspecified complications	0.033	0.967	0.000
E13.8 With unspecified complications	0.033	0.967	0.000
E13.7 With multiple complications	0.033	0.967	0.000
E13.6 With other specified complications	0.033	0.967	0.000
E13.5 With peripheral circulatory complications	0.033	0.967	0.000
E13.4 With neurological complications	0.033	0.967	0.000
E13.2 With renal complications	0.033	0.967	0.000
E13.1 With ketoacidosis	0.033	0.967	0.000
E13.0 With coma	0.033	0.967	0.000
E10.0 With coma	0.033	0.967	0.000
E13.3 With ophthalmic complications	0.032	0.968	0.000
E14.6 With other specified complications	0.032	0.968	0.000
E14.3 With ophthalmic complications	0.031	0.969	0.000
E10.2 With renal complications	0.031	0.969	0.000
E14.5 With peripheral circulatory complications	0.031	0.969	0.000
E14.2 Withrenal complications	0.031	0.969	0.000
E14.0 With coma	0.029	0.971	0.000
E14.7 With multiple complications	0.029	0.971	0.000
E10.5 With peripheral circulatory complications	0.027	0.973	0.000
E10.7 With multiple complications	0.027	0.973	0.000
E14.1 With ketoacidosis	0.026	0.974	0.000
E14.4 With neurological complications	0.026	0.974	0.000
E14.8 With unspecified complications	0.024	0.976	0.000
E10.6 With other specified complications	0.022	0.978	0.000
E13.9 Without complications	0.019	0.981	0.000
K83 Other diseases of biliary tract	0.000	0.986	0.014
O42.9 Premature rupture of membranes, unspecified	0.013	0.987	0.000
K83.4 Spasm of sphincter of Oddi	0.000	0.989	0.011
K83.5 Biliary cyst	0.000	0.989	0.010
K83.3 Fistula of bile duct	0.000	0.990	0.010
H93.1 Tinnitus	0.000	0.991	0.009
K83.2 Perforation of bile duct	0.000	0.991	0.009
E10.4 With neurological complications	0.008	0.991	0.001
E10.1 With ketoacidosis	0.007	0.992	0.001
K83.9 Disease of biliary tract, unspecified	0.000	0.993	0.007
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.993	0.007
L73.9 Follicular disorder, unspecified	0.006	0.994	0.000
D11.0 Parotid gland	0.006	0.994	0.000
R54 Senility	0.006	0.994	0.000
L73.2 Hidradenitis suppurativa	0.006	0.994	0.000
H36.0 Diabetic retinopathy	0.006	0.994	0.000
L73 Other follicular disorders	0.006	0.994	0.000
K83.0 Cholangitis	0.000	0.994	0.006
C25.0 Head of pancreas	0.005	0.995	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.005	0.995	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.995	0.005
E05.9 Thyrotoxicosis, unspecified	0.000	0.995	0.005
E27.2 Addisonian crisis	0.000	0.996	0.004
W06.0 Home	0.004	0.996	0.000
L73.1 Pseudofolliculitis barbae	0.004	0.996	0.000
L73.0 Acne keloid	0.004	0.996	0.000
C25 Malignant neoplasm of pancreas	0.004	0.996	0.000
L73.8 Other specified follicular disorders	0.004	0.996	0.000
C25.9 Pancreas, unspecified	0.004	0.996	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.000	0.996	0.004
O86.0 Infection of obstetric surgical wound	0.004	0.996	0.000
O86 Other puerperal infections	0.004	0.996	0.000
C25.4 Endocrine pancreas	0.004	0.996	0.000
I44.0 Atrioventricular block, first degree	0.000	0.996	0.004
C25.3 Pancreatic duct	0.004	0.996	0.000
H93 Other disorders of ear, not elsewhere classified	0.000	0.996	0.004
O86.1 Other infection of genital tract following delivery	0.004	0.996	0.000
E27 Other disorders of adrenal gland	0.000	0.996	0.003
O85-O92 Complications predominantly related to the puerperium	0.004	0.996	0.000
O90 Complications of the puerperium, not elsewhere classified	0.003	0.997	0.000
C25.8 Overlapping lesion of pancreas	0.003	0.997	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.003	0.997	0.000
O86.8 Other specified puerperal infections	0.003	0.997	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.003	0.997	0.000
O90.9 Complication of the puerperium, unspecified	0.003	0.997	0.000
O86.4 Pyrexia of unknown origin following delivery	0.003	0.997	0.000
O86.2 Urinary tract infection following delivery	0.003	0.997	0.000
C25.2 Tail of pancreas	0.003	0.997	0.000
C25.1 Body of pancreas	0.003	0.997	0.000
O86.3 Other genito-urinary tract infections following delivery	0.003	0.997	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.003	0.997	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.003	0.997	0.000
H93.2 Other abnormal auditory perceptions	0.000	0.997	0.003
O85 Puerperal sepsis	0.003	0.997	0.000
H93.8 Other specified disorders of ear	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.003
O87 Venous complications in the puerperium	0.003	0.997	0.000
C25.7 Other parts of pancreas	0.003	0.997	0.000
L71.9 Rosacea, unspecified	0.003	0.997	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.003	0.997	0.000
T85.2 Mechanical complication of intraocular lens	0.003	0.997	0.000
H93.0 Degenerative and vascular disorders of ear	0.000	0.997	0.003
O90.0 Disruption of Caesarean section wound	0.003	0.997	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.997	0.003
E27.0 Other adrenocortical overactivity	0.000	0.997	0.003
O88 Obstetric embolism	0.003	0.997	0.000
O90.5 Postpartum thyroiditis	0.003	0.997	0.000
O90.4 Postpartum acute renal failure	0.003	0.997	0.000
O90.3 Cardiomyopathy in the puerperium	0.003	0.997	0.000
O92.1 Cracked nipple associated with childbirth	0.003	0.997	0.000
H93.3 Disorders of acoustic nerve	0.000	0.997	0.003
E14.9 Without complications	0.003	0.997	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.003	0.997	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
O92.7 Other and unspecified disorders of lactation	0.002	0.997	0.000
O92.6 Galactorrhoea	0.002	0.997	0.000
O92.5 Suppressed lactation	0.002	0.997	0.000
O92.4 Hypogalactia	0.002	0.997	0.000
O92.3 Agalactia	0.002	0.997	0.000
O92.0 Retracted nipple associated with childbirth	0.002	0.997	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.997	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.003	0.997	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.002	0.997	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.002	0.997	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.002	0.997	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.002	0.997	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.997	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.002	0.997	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.002	0.997	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.002	0.997	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.002	0.997	0.000
O90.1 Disruption of perineal obstetric wound	0.003	0.997	0.000
O90.2 Haematoma of obstetric wound	0.002	0.997	0.000
H36 Retinal disorders in diseases classified elsewhere	0.003	0.997	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.003	0.997	0.000
O91 Infections of breast associated with childbirth	0.002	0.997	0.000
L71 Rosacea	0.003	0.997	0.000
O89 Complications of anaesthesia during the puerperium	0.002	0.997	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.003	0.997	0.000
J84 Other interstitial pulmonary diseases	0.000	0.997	0.003
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
J84.8 Other specified interstitial pulmonary diseases	0.000	0.997	0.003
M80.5 Idiopathic osteoporosis with pathological fracture	0.003	0.997	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.003	0.997	0.000
C45.9 Mesothelioma, unspecified	0.002	0.997	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.998	0.002
O87.9 Venous complication in the puerperium, unspecified	0.002	0.998	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.002	0.998	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.002	0.998	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.002	0.998	0.000
H05.0 Acute inflammation of orbit	0.002	0.998	0.000
W06 Fall involving bed	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
H93.9 Disorder of ear, unspecified	0.000	0.998	0.002
O87.8 Other venous complications in the puerperium	0.002	0.998	0.000
C18.4 Transverse colon	0.002	0.998	0.000
O88.8 Other obstetric embolism	0.002	0.998	0.000
O88.3 Obstetric pyaemic and septic embolism	0.002	0.998	0.000
O88.2 Obstetric blood-clot embolism	0.002	0.998	0.000
O88.1 Amniotic fluid embolism	0.002	0.998	0.000
O88.0 Obstetric air embolism	0.002	0.998	0.000
L71.1 Rhinophyma	0.002	0.998	0.000
Z71.9 Counselling, unspecified	0.002	0.998	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.002	0.998	0.000
W06.1 Residential institution	0.002	0.998	0.000
J33.9 Nasal polyp, unspecified	0.002	0.998	0.000
O91.1 Abscess of breast associated with childbirth	0.002	0.998	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.002	0.998	0.000
L60-L75 Disorders of skin appendages	0.002	0.998	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.002	0.998	0.000
O87.2 Haemorrhoids in the puerperium	0.002	0.998	0.000
O91.0 Infection of nipple associated with childbirth	0.002	0.998	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.998	0.002
L71.0 Perioral dermatitis	0.002	0.998	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.002	0.998	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.002	0.998	0.000
O89.6 Failed or difficult intubation during the puerperium	0.002	0.998	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.002	0.998	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.002	0.998	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.002	0.998	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.002	0.998	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.002	0.998	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
L68.0 Hirsutism	0.002	0.998	0.000
L71.8 Other rosacea	0.002	0.998	0.000
L68 Hypertrichosis	0.002	0.998	0.000
J84.0 Alveolar and parietoalveolar conditions	0.000	0.998	0.002
D25.1 Intramural leiomyoma of uterus	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.002	0.998	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.002	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.998	0.002
O42 Premature rupture of membranes	0.002	0.998	0.000
W06.2 School, other institution and public administrative area	0.002	0.998	0.000
W06.8 Other specified place	0.002	0.998	0.000
W06.7 Farm	0.002	0.998	0.000
W06.6 Industrial and construction area	0.002	0.998	0.000
W06.5 Trade and service area	0.002	0.998	0.000
W06.4 Street and highway	0.002	0.998	0.000
W06.3 Sports and athletics area	0.002	0.998	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.002	0.998	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.002	0.998	0.000
S43.0 Dislocation of shoulder joint	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.002	0.998	0.000
D11 Benign neoplasm of major salivary glands	0.002	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
W06.9 Unspecified place	0.002	0.998	0.000
L63 Alopecia areata	0.002	0.998	0.000
K07.3 Anomalies of tooth position	0.000	0.998	0.002
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.002	0.998	0.000
M89.98 Disorder of bone, unspecified (Other)	0.000	0.998	0.002
L75 Apocrine sweat disorders	0.002	0.998	0.000
L74 Eccrine sweat disorders	0.002	0.998	0.000
L67 Hair colour and hair shaft abnormalities	0.002	0.998	0.000
L64 Androgenic alopecia	0.002	0.998	0.000
L62 Nail disorders in diseases classified elsewhere	0.002	0.998	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.002	0.998	0.000
W10.8 Other specified place	0.002	0.998	0.000
L68.9 Hypertrichosis, unspecified	0.002	0.998	0.000
L68.8 Other hypertrichosis	0.002	0.998	0.000
L68.3 Polytrichia	0.002	0.998	0.000
L68.2 Localised hypertrichosis	0.002	0.998	0.000
L68.1 Acquired hypertrichosis lanuginosa	0.002	0.998	0.000
H26.4 After-cataract	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
C45.7 Mesothelioma of other sites	0.002	0.998	0.000
K83.1 Obstruction of bile duct	0.000	0.998	0.002
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.998	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.998	0.002
M89.9 Disorder of bone, unspecified	0.000	0.998	0.002
Z96.1 Presence of intraocular lens	0.002	0.998	0.000
C45 Mesothelioma	0.002	0.998	0.000
W06.28 Fall involving bed; School, other institution and public administrative area; While engaged in other specified activities	0.001	0.998	0.000
K63.1 Perforation of intestine (nontraumatic)	0.002	0.998	0.000
L66 Cicatricial alopecia [scarring hair loss]	0.002	0.998	0.000
L63.9 Alopecia areata, unspecified	0.002	0.998	0.000
M80.8 Other osteoporosis with pathological fracture	0.002	0.998	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.000
Z93.2 Ileostomy status	0.002	0.998	0.000
S43.4 Sprain and strain of shoulder joint	0.000	0.998	0.002
L63.8 Other alopecia areata	0.001	0.998	0.000
L63.2 Ophiasis	0.001	0.998	0.000
L63.1 Alopecia universalis	0.001	0.998	0.000
L63.0 Alopecia (capitis) totalis	0.001	0.998	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.000	0.998	0.002
T93.2 Sequelae of other fractures of lower limb	0.002	0.998	0.000
L60 Nail disorders	0.002	0.998	0.000
L62.8 Nail disorders in other diseases classified elsewhere	0.001	0.998	0.000
L62.0 Clubbed nail pachydermoperiostosis	0.001	0.998	0.000
L64.9 Androgenic alopecia, unspecified	0.001	0.998	0.000
L64.8 Other androgenic alopecia	0.001	0.998	0.000
L64.0 Drug-induced androgenic alopecia	0.001	0.998	0.000
L67.9 Hair colour and hair shaft abnormality, unspecified	0.001	0.998	0.000
L67.8 Other hair colour and hair shaft abnormalities	0.001	0.998	0.000
L67.1 Variations in hair colour	0.001	0.998	0.000
L67.0 Trichorrhexis nodosa	0.001	0.998	0.000
L74.9 Eccrine sweat disorder, unspecified	0.001	0.998	0.000
L74.8 Other eccrine sweat disorders	0.001	0.998	0.000
L74.4 Anhidrosis	0.001	0.998	0.000
L74.3 Miliaria, unspecified	0.001	0.998	0.000
L74.2 Miliaria profunda	0.001	0.998	0.000
L74.1 Miliaria crystallina	0.001	0.998	0.000
L74.0 Miliaria rubra	0.001	0.998	0.000
L75.9 Apocrine sweat disorder, unspecified	0.001	0.998	0.000
L75.8 Other apocrine sweat disorders	0.001	0.998	0.000
L75.2 Apocrine miliaria	0.001	0.998	0.000
L75.1 Chromhidrosis	0.001	0.998	0.000
L75.0 Bromhidrosis	0.001	0.998	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.002	0.998	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.002	0.998	0.000
L65 Other nonscarring hair loss	0.001	0.998	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.000	0.998	0.002
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.998	0.001
D11.7 Other major salivary glands	0.001	0.998	0.000
L60.2 Onychogryphosis	0.002	0.998	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.001	0.998	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.001	0.998	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.001	0.998	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.001	0.998	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.998	0.001
C45.0 Mesothelioma of pleura	0.002	0.998	0.000
H57.1 Ocular pain	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.001	0.998	0.000
X59.3 Sports and athletics area	0.000	0.998	0.001
L70 Acne	0.001	0.998	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.998	0.002
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.998	0.001
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.998	0.002
J86.9 Pyothorax without fistula	0.002	0.998	0.000
M93.9 Osteochondropathy, unspecified	0.000	0.998	0.001
J10 Influenza due to identified influenza virus	0.002	0.998	0.000
C45.2 Mesothelioma of pericardium	0.001	0.998	0.000
C45.1 Mesothelioma of peritoneum	0.001	0.998	0.000
D04.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
G41.9 Status epilepticus, unspecified	0.001	0.998	0.000
L60.1 Onycholysis	0.001	0.998	0.000
L66.8 Other cicatricial alopecia	0.001	0.998	0.000
L66.4 Folliculitis ulerythematosa reticulata	0.001	0.998	0.000
L66.3 Perifolliculitis capitis abscedens	0.001	0.998	0.000
L66.2 Folliculitis decalvans	0.001	0.998	0.000
L66.0 Pseudopelade	0.001	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.998	0.002
L60.3 Nail dystrophy	0.001	0.998	0.000
W29.9 Unspecified place	0.000	0.998	0.001
H57.9 Disorder of eye and adnexa, unspecified	0.001	0.999	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.999	0.001
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.001	0.999	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.999	0.001
K07.2 Anomalies of dental arch relationship	0.000	0.999	0.001
R70.0 Elevated erythrocyte sedimentation rate	0.001	0.999	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
E05.8 Other thyrotoxicosis	0.000	0.999	0.001
J05.1 Acute epiglottitis	0.001	0.999	0.000
L66.9 Cicatricial alopecia, unspecified	0.001	0.999	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.999	0.001
S43.2 Dislocation of sternoclavicular joint	0.000	0.999	0.001
L60.9 Nail disorder, unspecified	0.001	0.999	0.000
L60.8 Other nail disorders	0.001	0.999	0.000
L60.5 Yellow nail syndrome	0.001	0.999	0.000
L60.4 Beau's lines	0.001	0.999	0.000
L66.1 Lichen planopilaris	0.001	0.999	0.000
G30.1 Alzheimer's disease with late onset	0.000	0.999	0.001
L12.1 Cicatricial pemphigoid	0.000	0.999	0.001
L65.8 Other specified nonscarring hair loss	0.001	0.999	0.000
L65.2 Alopecia mucinosa	0.001	0.999	0.000
L65.1 Anagen effluvium	0.001	0.999	0.000
L65.0 Telogen effluvium	0.001	0.999	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.001	0.999	0.000
K80.4 Calculus of bile duct with cholecystitis	0.000	0.999	0.001
Y65.4 Failure to introduce or to remove other tube or instrument	0.000	0.999	0.001
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.999	0.001
G30.8 Other Alzheimer's disease	0.000	0.999	0.001
L70.8 Other acne	0.001	0.999	0.000
L70.5 Acne excoriee des jeunes filles	0.001	0.999	0.000
L70.4 Infantile acne	0.001	0.999	0.000
L70.3 Acne tropica	0.001	0.999	0.000
L70.2 Acne varioliformis	0.001	0.999	0.000
L70.1 Acne conglobata	0.001	0.999	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.999	0.001
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.999	0.001
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.999	0.001
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.001	0.999	0.000
M10.94 Gout, unspecified (Hand)	0.001	0.999	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.999	0.001
J10.8 Influenza with other manifestations, influenza virus identified	0.001	0.999	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.999	0.001
W10.4 Street and highway	0.001	0.999	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.999	0.001
S02.60 Fracture of mandible (closed)	0.001	0.999	0.000
E05.5 Thyroid crisis or storm	0.000	0.999	0.001
E05.4 Thyrotoxicosis factitia	0.000	0.999	0.001
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.999	0.001
S93.1 Dislocation of toe(s)	0.000	0.999	0.001
M80.88 Other osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.999	0.001
M80.9 Unspecified osteoporosis with pathological fracture	0.001	0.999	0.000
G30 Alzheimer's disease	0.000	0.999	0.001
W10 Fall on and from stairs and steps	0.001	0.999	0.000
K60.2 Anal fissure, unspecified	0.001	0.999	0.000
L70.9 Acne, unspecified	0.001	0.999	0.000
W10.3 Sports and athletics area	0.001	0.999	0.000
Y84.6 Urinary catheterisation	0.000	0.999	0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.999	0.001
I60.8 Other subarachnoid haemorrhage	0.000	0.999	0.001
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.999	0.001
T93 Sequelae of injuries of lower limb	0.001	0.999	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.999	0.001
D11.9 Major salivary gland, unspecified	0.001	0.999	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
C32.1 Supraglottis	0.000	0.999	0.001
R44.0 Auditory hallucinations	0.001	0.999	0.000
U80.0 Penicillin resistant agent	0.000	0.999	0.001
C81.1 Nodular sclerosis	0.000	0.999	0.001
H11.9 Disorder of conjunctiva, unspecified	0.000	0.999	0.001
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
I86.8 Varicose veins of other specified sites	0.001	0.999	0.000
L12.9 Pemphigoid, unspecified	0.000	0.999	0.001
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.999	0.001
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.001	0.999	0.000
V80.9 Rider or occupant injured in other and unspecified transport accidents	0.001	0.999	0.000
W10.6 Industrial and construction area	0.001	0.999	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
I30.9 Acute pericarditis, unspecified	0.001	0.999	0.000
L12.0 Bullous pemphigoid	0.000	0.999	0.001
M67.1 Other contracture of tendon (sheath)	0.000	0.999	0.001
Q17.5 Prominent ear	0.001	0.999	0.000
R44.1 Visual hallucinations	0.001	0.999	0.000
T23.2 Burn of second degree of wrist and hand	0.001	0.999	0.000
W10.9 Unspecified place	0.001	0.999	0.000
W10.5 Trade and service area	0.001	0.999	0.000
W10.2 School, other institution and public administrative area	0.001	0.999	0.000
W10.0 Home	0.001	0.999	0.000
W10.7 Farm	0.001	0.999	0.000
I60 Subarachnoid haemorrhage	0.000	0.999	0.001
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.999	0.001
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.001	0.999	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.001	0.999	0.000
M65.34 Trigger finger-Hand	0.001	0.999	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.999	0.001
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.999	0.001
K07.9 Dentofacial anomaly, unspecified	0.000	0.999	0.001
C09.9 Tonsil, unspecified	0.001	0.999	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.001	0.999	0.000
O82.1 Delivery by emergency Caesarean section	0.000	0.999	0.001
R87.7 Abnormal histological findings	0.000	0.999	0.001
W10.1 Residential institution	0.001	0.999	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.001	0.999	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.001	0.999	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.000	0.999	0.001
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.999	0.001
T79.7 Traumatic subcutaneous emphysema	0.000	0.999	0.001
Z90.8 Acquired absence of other organs	0.000	0.999	0.001
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.999	0.001
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
W10.08 Fall on and from stairs and steps; Home; While engaged in other specified activities	0.001	0.999	0.000
W10.04 Fall on and from stairs and steps; Home; While resting, sleeping, eating or engaging in other vital activities	0.001	0.999	0.000
W10.03 Fall on and from stairs and steps; Home; While engaged in other types of work	0.001	0.999	0.000
W10.29 Fall on and from stairs and steps; School, other institution and public administrative area; During unspecified activity	0.001	0.999	0.000
W10.59 Fall on and from stairs and steps; Trade and service area; During unspecified activity	0.001	0.999	0.000
W10.92 Fall on and from stairs and steps; Unspecified place; While working for income	0.001	0.999	0.000
W10.90 Fall on and from stairs and steps; Unspecified place; While engaged in sports activity	0.001	0.999	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.999	0.001
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.999	0.001
J86.0 Pyothorax with fistula	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations