TreeWAS – Variant ID: rs17193122

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J45.9 Asthma, unspecified	0.000	0.320	0.680
J45 Asthma	0.000	0.393	0.607
J40-J47 Chronic lower respiratory diseases	0.000	0.446	0.554
J47 Bronchiectasis	0.000	0.468	0.532
E83.1 Disorders of iron metabolism	0.516	0.484	0.000
J40 Bronchitis, not specified as acute or chronic	0.000	0.496	0.504
J44 Other chronic obstructive pulmonary disease	0.000	0.498	0.502
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.525	0.475
J45.8 Mixed asthma	0.000	0.565	0.435
J45.1 Nonallergic asthma	0.000	0.565	0.435
J45.0 Predominantly allergic asthma	0.000	0.566	0.433
J41 Simple and mucopurulent chronic bronchitis	0.000	0.602	0.397
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.622	0.378
J46 Status asthmaticus	0.000	0.637	0.362
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.666	0.334
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.678	0.322
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.715	0.285
J41.1 Mucopurulent chronic bronchitis	0.000	0.715	0.285
J41.0 Simple chronic bronchitis	0.000	0.715	0.285
J43 Emphysema	0.000	0.720	0.280
E83 Disorders of mineral metabolism	0.269	0.731	0.000
E03.9 Hypothyroidism, unspecified	0.260	0.740	0.000
E03 Other hypothyroidism	0.238	0.762	0.000
J42 Unspecified chronic bronchitis	0.001	0.764	0.236
E70-E90 Metabolic disorders	0.224	0.776	0.000
E00-E07 Disorders of thyroid gland	0.221	0.779	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.212	0.788	0.000
J43.8 Other emphysema	0.000	0.799	0.201
J43.1 Panlobular emphysema	0.000	0.799	0.201
J43.0 MacLeod's syndrome	0.000	0.799	0.201
J43.2 Centrilobular emphysema	0.000	0.801	0.199
E73 Lactose intolerance	0.196	0.804	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.193	0.807	0.000
E83.8 Other disorders of mineral metabolism	0.193	0.807	0.000
E83.2 Disorders of zinc metabolism	0.193	0.807	0.000
E83.0 Disorders of copper metabolism	0.193	0.807	0.000
E85 Amyloidosis	0.192	0.808	0.000
S60-S69 Injuries to the wrist and hand	0.188	0.812	0.000
S61 Open wound of wrist and hand	0.186	0.814	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.184	0.816	0.000
S61.0 Open wound of finger(s) without damage to nail	0.182	0.818	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.179	0.821	0.000
S61.8 Open wound of other parts of wrist and hand	0.179	0.821	0.000
E07 Other disorders of thyroid	0.178	0.822	0.000
E03.8 Other specified hypothyroidism	0.178	0.822	0.000
E73.9 Lactose intolerance, unspecified	0.177	0.823	0.000
E20-E35 Disorders of other endocrine glands	0.176	0.824	0.000
E06 Thyroiditis	0.174	0.825	0.000
E50-E64 Other nutritional deficiencies	0.173	0.827	0.000
E03.5 Myxoedema coma	0.171	0.829	0.000
E03.4 Atrophy of thyroid (acquired)	0.171	0.829	0.000
E03.3 Postinfectious hypothyroidism	0.171	0.829	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.171	0.829	0.000
E03.1 Congenital hypothyroidism without goitre	0.171	0.829	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.171	0.829	0.000
T66-T78 Other and unspecified effects of external causes	0.170	0.830	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.168	0.832	0.000
S64 Injury of nerves at wrist and hand level	0.166	0.834	0.000
E85.9 Amyloidosis, unspecified	0.165	0.834	0.000
E88 Other metabolic disorders	0.165	0.835	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.164	0.836	0.000
T78 Adverse effects, not elsewhere classified	0.163	0.837	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.162	0.838	0.000
E84 Cystic fibrosis	0.160	0.839	0.000
E79 Disorders of purine and pyrimidine metabolism	0.160	0.839	0.000
E77 Disorders of glycoprotein metabolism	0.160	0.839	0.000
E76 Disorders of glycosaminoglycan metabolism	0.160	0.839	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.160	0.839	0.000
E74 Other disorders of carbohydrate metabolism	0.160	0.839	0.000
E72 Other disorders of amino-acid metabolism	0.160	0.839	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.160	0.839	0.000
E70 Disorders of aromatic amino-acid metabolism	0.160	0.839	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.160	0.839	0.000
T78.4 Allergy, unspecified	0.160	0.840	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.159	0.841	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.159	0.841	0.000
E00 Congenital iodine-deficiency syndrome	0.159	0.841	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.159	0.841	0.000
S70-S79 Injuries to the hip and thigh	0.158	0.842	0.000
S50-S59 Injuries to the elbow and forearm	0.157	0.843	0.000
S10-S19 Injuries to the neck	0.155	0.845	0.000
E83.5 Disorders of calcium metabolism	0.154	0.845	0.000
S90-S99 Injuries to the ankle and foot	0.154	0.846	0.000
E40-E46 Malnutrition	0.153	0.847	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.153	0.847	0.000
E21.3 Hyperparathyroidism, unspecified	0.152	0.848	0.000
S20-S29 Injuries to the thorax	0.152	0.848	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.151	0.849	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.150	0.850	0.000
E83.4 Disorders of magnesium metabolism	0.149	0.851	0.000
E07.9 Disorder of thyroid, unspecified	0.147	0.853	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.146	0.854	0.000
E85.4 Organ-limited amyloidosis	0.144	0.856	0.000
S67 Crushing injury of wrist and hand	0.144	0.856	0.000
S00-S09 Injuries to the head	0.144	0.856	0.000
S61.7 Multiple open wounds of wrist and hand	0.143	0.857	0.000
E61 Deficiency of other nutrient elements	0.143	0.857	0.000
E83.3 Disorders of phosphorus metabolism	0.143	0.857	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.143	0.857	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.143	0.857	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.142	0.858	0.000
E29 Testicular dysfunction	0.142	0.858	0.000
E06.3 Autoimmune thyroiditis	0.141	0.859	0.000
E73.8 Other lactose intolerance	0.141	0.859	0.000
E73.1 Secondary lactase deficiency	0.141	0.859	0.000
E73.0 Congenital lactase deficiency	0.141	0.859	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.140	0.860	0.000
E55 Vitamin D deficiency	0.139	0.861	0.000
S02 Fracture of skull and facial bones	0.138	0.862	0.000
E85.8 Other amyloidosis	0.137	0.862	0.000
E85.3 Secondary systemic amyloidosis	0.137	0.862	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.137	0.862	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.137	0.862	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.137	0.862	0.000
S12 Fracture of neck	0.136	0.864	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.136	0.864	0.000
T75 Effects of other external causes	0.136	0.864	0.000
E88.8 Other specified metabolic disorders	0.135	0.865	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.135	0.865	0.000
S65 Injury of blood vessels at wrist and hand level	0.135	0.865	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.135	0.865	0.000
S99 Other and unspecified injuries of ankle and foot	0.135	0.865	0.000
E22 Hyperfunction of pituitary gland	0.134	0.866	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.134	0.866	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.133	0.867	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.133	0.867	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.132	0.868	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.132	0.868	0.000
T00-T07 Injuries involving multiple body regions	0.132	0.868	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.132	0.868	0.000
S79 Other and unspecified injuries of hip and thigh	0.132	0.868	0.000
S64.4 Injury of digital nerve of other finger	0.131	0.869	0.000
E34 Other endocrine disorders	0.129	0.871	0.000
T33-T35 Frostbite	0.129	0.871	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.129	0.871	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.129	0.871	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.129	0.871	0.000
E89.0 Postprocedural hypothyroidism	0.128	0.872	0.000
E07.8 Other specified disorders of thyroid	0.128	0.872	0.000
E07.1 Dyshormogenetic goitre	0.128	0.872	0.000
E07.0 Hypersecretion of calcitonin	0.128	0.872	0.000
S64.1 Injury of median nerve at wrist and hand level	0.127	0.873	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.126	0.873	0.000
E32 Diseases of thymus	0.126	0.873	0.000
E31 Polyglandular dysfunction	0.126	0.873	0.000
E30 Disorders of puberty, not elsewhere classified	0.126	0.873	0.000
E26 Hyperaldosteronism	0.126	0.873	0.000
E25 Adrenogenital disorders	0.126	0.873	0.000
E24 Cushing's syndrome	0.126	0.873	0.000
E20 Hypoparathyroidism	0.126	0.873	0.000
S90 Superficial injury of ankle and foot	0.126	0.874	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.126	0.874	0.000
S72 Fracture of femur	0.126	0.874	0.000
S64.3 Injury of digital nerve of thumb	0.126	0.874	0.000
S56 Injury of muscle and tendon at forearm level	0.125	0.874	0.000
S70 Superficial injury of hip and thigh	0.125	0.875	0.000
E06.9 Thyroiditis, unspecified	0.125	0.875	0.000
E06.5 Other chronic thyroiditis	0.125	0.875	0.000
E06.4 Drug-induced thyroiditis	0.125	0.875	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.125	0.875	0.000
E06.1 Subacute thyroiditis	0.125	0.875	0.000
E06.0 Acute thyroiditis	0.125	0.875	0.000
T78.2 Anaphylactic shock, unspecified	0.125	0.875	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.125	0.875	0.000
E21.0 Primary hyperparathyroidism	0.124	0.876	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.124	0.876	0.000
E63 Other nutritional deficiencies	0.124	0.876	0.000
E56 Other vitamin deficiencies	0.124	0.876	0.000
E51 Thiamine deficiency	0.124	0.876	0.000
E50 Vitamin A deficiency	0.124	0.876	0.000
E60 Dietary zinc deficiency	0.124	0.876	0.000
E59 Dietary selenium deficiency	0.124	0.876	0.000
E58 Dietary calcium deficiency	0.124	0.876	0.000
E54 Ascorbic acid deficiency	0.124	0.876	0.000
E52 Niacin deficiency [pellagra]	0.124	0.876	0.000
S68 Traumatic amputation of wrist and hand	0.124	0.876	0.000
S02.8 Fractures of other skull and facial bones	0.123	0.877	0.000
S27 Injury of other and unspecified intrathoracic organs	0.123	0.877	0.000
S51 Open wound of forearm	0.123	0.877	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.122	0.877	0.000
S10 Superficial injury of neck	0.122	0.878	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.122	0.878	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.122	0.878	0.000
E61.1 Iron deficiency	0.122	0.878	0.000
T74 Maltreatment syndromes	0.122	0.878	0.000
T73 Effects of other deprivation	0.122	0.878	0.000
T70 Effects of air pressure and water pressure	0.122	0.878	0.000
T69 Other effects of reduced temperature	0.122	0.878	0.000
T67 Effects of heat and light	0.122	0.878	0.000
T71 Asphyxiation	0.122	0.878	0.000
T66 Unspecified effects of radiation	0.122	0.878	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.122	0.878	0.000
E89.2 Postprocedural hypoparathyroidism	0.121	0.879	0.000
S99.9 Unspecified injury of ankle and foot	0.121	0.879	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.121	0.879	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.121	0.879	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.121	0.879	0.000
E89.5 Postprocedural testicular hypofunction	0.121	0.879	0.000
E89.4 Postprocedural ovarian failure	0.121	0.879	0.000
E89.3 Postprocedural hypopituitarism	0.121	0.879	0.000
E89.1 Postprocedural hypoinsulinaemia	0.121	0.879	0.000
S52 Fracture of forearm	0.120	0.880	0.000
S50 Superficial injury of forearm	0.120	0.880	0.000
S21 Open wound of thorax	0.119	0.881	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.119	0.881	0.000
S64.8 Injury of other nerves at wrist and hand level	0.119	0.881	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.119	0.881	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.119	0.881	0.000
E88.9 Metabolic disorder, unspecified	0.118	0.881	0.000
E88.3 Tumour lysis syndrome	0.118	0.881	0.000
E88.2 Lipomatosis, not elsewhere classified	0.118	0.881	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.118	0.881	0.000
S22.3 Fracture of rib	0.118	0.882	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.118	0.882	0.000
E21.4 Other specified disorders of parathyroid gland	0.118	0.882	0.000
E21.2 Other hyperparathyroidism	0.118	0.882	0.000
S62 Fracture at wrist and hand level	0.118	0.882	0.000
T79-T79 Certain early complications of trauma	0.117	0.882	0.000
T78.9 Adverse effect, unspecified	0.117	0.883	0.000
T78.8 Other adverse effects, not elsewhere classified	0.117	0.883	0.000
E29.1 Testicular hypofunction	0.117	0.883	0.000
E65-E68 Obesity and other hyperalimentation	0.117	0.883	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.117	0.883	0.000
T23 Burn and corrosion of wrist and hand	0.116	0.884	0.000
S12.2 Fracture of other specified cervical vertebra	0.115	0.885	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.115	0.885	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.115	0.885	0.000
E70.3 Albinism	0.115	0.885	0.000
E70.2 Disorders of tyrosine metabolism	0.115	0.885	0.000
E70.1 Other hyperphenylalaninaemias	0.115	0.885	0.000
E70.0 Classical phenylketonuria	0.115	0.885	0.000
E71.3 Disorders of fatty-acid metabolism	0.115	0.885	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.115	0.885	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.115	0.885	0.000
E71.0 Maple-syrup-urine disease	0.115	0.885	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.115	0.885	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.115	0.885	0.000
E72.5 Disorders of glycine metabolism	0.115	0.885	0.000
E72.4 Disorders of ornithine metabolism	0.115	0.885	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.115	0.885	0.000
E72.2 Disorders of urea cycle metabolism	0.115	0.885	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.115	0.885	0.000
E72.0 Disorders of amino-acid transport	0.115	0.885	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.115	0.885	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.115	0.885	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.115	0.885	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.115	0.885	0.000
E74.2 Disorders of galactose metabolism	0.115	0.885	0.000
E74.1 Disorders of fructose metabolism	0.115	0.885	0.000
E74.0 Glycogen storage disease	0.115	0.885	0.000
E75.6 Lipid storage disorder, unspecified	0.115	0.885	0.000
E75.5 Other lipid storage disorders	0.115	0.885	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.115	0.885	0.000
E75.3 Sphingolipidosis, unspecified	0.115	0.885	0.000
E75.2 Other sphingolipidosis	0.115	0.885	0.000
E75.1 Other gangliosidosis	0.115	0.885	0.000
E75.0 GM2 gangliosidosis	0.115	0.885	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.115	0.885	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.115	0.885	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.115	0.885	0.000
E76.2 Other mucopolysaccharidoses	0.115	0.885	0.000
E76.1 Mucopolysaccharidosis, type II	0.115	0.885	0.000
E76.0 Mucopolysaccharidosis, type I	0.115	0.885	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.115	0.885	0.000
E77.8 Other disorders of glycoprotein metabolism	0.115	0.885	0.000
E77.1 Defects in glycoprotein degradation	0.115	0.885	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.115	0.885	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.115	0.885	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.115	0.885	0.000
E79.1 Lesch-Nyhan syndrome	0.115	0.885	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.115	0.885	0.000
E84.9 Cystic fibrosis, unspecified	0.115	0.885	0.000
E84.8 Cystic fibrosis with other manifestations	0.115	0.885	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.115	0.885	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.115	0.885	0.000
S02.3 Fracture of orbital floor	0.115	0.885	0.000
S06 Intracranial injury	0.115	0.885	0.000
E55.9 Vitamin D deficiency, unspecified	0.115	0.885	0.000
S31 Open wound of abdomen, lower back and pelvis	0.114	0.885	0.000
E05.8 Other thyrotoxicosis	0.114	0.886	0.000
E05.5 Thyroid crisis or storm	0.114	0.886	0.000
E05.4 Thyrotoxicosis factitia	0.114	0.886	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.114	0.886	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.114	0.886	0.000
E28 Ovarian dysfunction	0.114	0.886	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.114	0.886	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.114	0.886	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.114	0.886	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.114	0.886	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.114	0.886	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.114	0.886	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.114	0.886	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.114	0.886	0.000
S78 Traumatic amputation of hip and thigh	0.114	0.886	0.000
S77 Crushing injury of hip and thigh	0.114	0.886	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.114	0.886	0.000
S75 Injury of blood vessels at hip and thigh level	0.114	0.886	0.000
S74 Injury of nerves at hip and thigh level	0.114	0.886	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.113	0.887	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.113	0.887	0.000
S79.9 Unspecified injury of hip and thigh	0.113	0.887	0.000
S14 Injury of nerves and spinal cord at neck level	0.112	0.887	0.000
S59 Other and unspecified injuries of forearm	0.112	0.887	0.000
S58 Traumatic amputation of forearm	0.112	0.887	0.000
S57 Crushing injury of forearm	0.112	0.887	0.000
S55 Injury of blood vessels at forearm level	0.112	0.887	0.000
S54 Injury of nerves at forearm level	0.112	0.887	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.112	0.887	0.000
E23 Hypofunction and other disorders of pituitary gland	0.112	0.888	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.112	0.888	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.112	0.888	0.000
T75.4 Effects of electric current	0.111	0.888	0.000
S60 Superficial injury of wrist and hand	0.111	0.889	0.000
S22.30 Fracture of rib (closed)	0.111	0.889	0.000
S17 Crushing injury of neck	0.111	0.889	0.000
S15 Injury of blood vessels at neck level	0.111	0.889	0.000
S11 Open wound of neck	0.111	0.889	0.000
S18 Traumatic amputation at neck level	0.111	0.889	0.000
S16 Injury of muscle and tendon at neck level	0.111	0.889	0.000
E46 Unspecified protein-energy malnutrition	0.111	0.889	0.000
S02.2 Fracture of nasal bones	0.110	0.890	0.000
S98 Traumatic amputation of ankle and foot	0.110	0.890	0.000
S97 Crushing injury of ankle and foot	0.110	0.890	0.000
S95 Injury of blood vessels at ankle and foot level	0.110	0.890	0.000
S94 Injury of nerves at ankle and foot level	0.110	0.890	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.110	0.890	0.000
E45 Retarded development following protein-energy malnutrition	0.110	0.890	0.000
E43 Unspecified severe protein-energy malnutrition	0.110	0.890	0.000
E42 Marasmic kwashiorkor	0.110	0.890	0.000
E41 Nutritional marasmus	0.110	0.890	0.000
E40 Kwashiorkor	0.110	0.890	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.110	0.890	0.000
E80.6 Other disorders of bilirubin metabolism	0.110	0.890	0.000
E80.5 Crigler-Najjar syndrome	0.110	0.890	0.000
E80.3 Defects of catalase and peroxydase	0.110	0.890	0.000
E80.2 Other porphyria	0.110	0.890	0.000
E80.1 Porphyria cutanea tarda	0.110	0.890	0.000
E80.0 Hereditary erythropoietic porphyria	0.110	0.890	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.109	0.890	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.109	0.891	0.000
S26 Injury of heart	0.109	0.891	0.000
S25 Injury of blood vessels of thorax	0.109	0.891	0.000
S24 Injury of nerves and spinal cord at thorax level	0.109	0.891	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.109	0.891	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.109	0.891	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.109	0.891	0.000
S69 Other and unspecified injuries of wrist and hand	0.108	0.891	0.000
S02.4 Fracture of malar and maxillary bones	0.108	0.892	0.000
S72.3 Fracture of shaft of femur	0.108	0.892	0.000
S71 Open wound of hip and thigh	0.108	0.892	0.000
S12.9 Fracture of neck, part unspecified	0.106	0.894	0.000
E53 Deficiency of other B group vitamins	0.106	0.894	0.000
S02.1 Fracture of base of skull	0.106	0.894	0.000
T14 Injury of unspecified body region	0.105	0.895	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.104	0.896	0.000
T91 Sequelae of injuries of neck and trunk	0.104	0.896	0.000
S05 Injury of eye and orbit	0.103	0.896	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.103	0.897	0.000
S08 Traumatic amputation of part of head	0.103	0.897	0.000
S07 Crushing injury of head	0.103	0.897	0.000
S04 Injury of cranial nerves	0.103	0.897	0.000
S12.1 Fracture of second cervical vertebra	0.103	0.897	0.000
E61.9 Deficiency of nutrient element, unspecified	0.103	0.897	0.000
E61.8 Deficiency of other specified nutrient elements	0.103	0.897	0.000
E61.7 Deficiency of multiple nutrient elements	0.103	0.897	0.000
E61.6 Vanadium deficiency	0.103	0.897	0.000
E61.5 Molybdenum deficiency	0.103	0.897	0.000
E61.4 Chromium deficiency	0.103	0.897	0.000
E61.3 Manganese deficiency	0.103	0.897	0.000
E61.2 Magnesium deficiency	0.103	0.897	0.000
E61.0 Copper deficiency	0.103	0.897	0.000
S20 Superficial injury of thorax	0.103	0.897	0.000
E22.0 Acromegaly and pituitary gigantism	0.103	0.897	0.000
T25 Burn and corrosion of ankle and foot	0.102	0.897	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.102	0.897	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.102	0.897	0.000
T21 Burn and corrosion of trunk	0.102	0.897	0.000
T20 Burn and corrosion of head and neck	0.102	0.897	0.000
E86 Volume depletion	0.102	0.898	0.000
E29.9 Testicular dysfunction, unspecified	0.102	0.898	0.000
E29.8 Other testicular dysfunction	0.102	0.898	0.000
E29.0 Testicular hyperfunction	0.102	0.898	0.000
E80.4 Gilbert's syndrome	0.102	0.898	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.102	0.898	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.101	0.899	0.000
S40-S49 Injuries to the shoulder and upper arm	0.101	0.899	0.000
S90.8 Other superficial injuries of ankle and foot	0.101	0.899	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.101	0.899	0.000
S19 Other and unspecified injuries of neck	0.100	0.899	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.100	0.900	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.100	0.900	0.000
S12.7 Multiple fractures of cervical spine	0.100	0.900	0.000
E55.0 Rickets, active	0.100	0.900	0.000
T68 Hypothermia	0.100	0.900	0.000
S51.8 Open wound of other parts of forearm	0.100	0.900	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.099	0.900	0.000
S02.0 Fracture of vault of skull	0.099	0.901	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.099	0.901	0.000
S02.30 Fracture of orbital floor (closed)	0.099	0.901	0.000
S10.9 Superficial injury of neck, part unspecified	0.099	0.901	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.099	0.901	0.000
S02.7 Multiple fractures involving skull and facial bones	0.099	0.901	0.000
S72.0 Fracture of neck of femur	0.099	0.901	0.000
T17 Foreign body in respiratory tract	0.098	0.901	0.000
S92 Fracture of foot, except ankle	0.098	0.902	0.000
S02.5 Fracture of tooth	0.098	0.902	0.000
S12.8 Fracture of other parts of neck	0.098	0.902	0.000
S12.0 Fracture of first cervical vertebra	0.098	0.902	0.000
T02 Fractures involving multiple body regions	0.098	0.902	0.000
T18 Foreign body in alimentary tract	0.098	0.902	0.000
T13 Other injuries of lower limb, level unspecified	0.098	0.902	0.000
E34.0 Carcinoid syndrome	0.098	0.902	0.000
T11 Other injuries of upper limb, level unspecified	0.098	0.902	0.000
T09 Other injuries of spine and trunk, level unspecified	0.098	0.902	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.098	0.902	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.098	0.902	0.000
T12 Fracture of lower limb, level unspecified	0.098	0.902	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.098	0.902	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.098	0.902	0.000
T10 Fracture of upper limb, level unspecified	0.098	0.902	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.098	0.902	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.098	0.902	0.000
T08 Fracture of spine, level unspecified	0.098	0.902	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.098	0.902	0.000
S52.5 Fracture of lower end of radius	0.098	0.902	0.000
T75.8 Other specified effects of external causes	0.097	0.902	0.000
T75.3 Motion sickness	0.097	0.902	0.000
T75.2 Effects of vibration	0.097	0.902	0.000
T75.1 Drowning and nonfatal submersion	0.097	0.902	0.000
T75.0 Effects of lightning	0.097	0.902	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.097	0.903	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.097	0.903	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.097	0.903	0.000
S65.5 Injury of blood vessel(s) of other finger	0.097	0.903	0.000
S65.4 Injury of blood vessel(s) of thumb	0.097	0.903	0.000
S65.3 Injury of deep palmar arch	0.097	0.903	0.000
S65.2 Injury of superficial palmar arch	0.097	0.903	0.000
S65.1 Injury of radial artery at wrist and hand level	0.097	0.903	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.097	0.903	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.097	0.903	0.000
S37 Injury of urinary and pelvic organs	0.097	0.903	0.000
S36 Injury of intra-abdominal organs	0.097	0.903	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.097	0.903	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.097	0.903	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.097	0.903	0.000
S99.8 Other specified injuries of ankle and foot	0.097	0.903	0.000
S99.7 Multiple injuries of ankle and foot	0.097	0.903	0.000
S27.0 Traumatic pneumothorax	0.097	0.903	0.000
T23.3 Burn of third degree of wrist and hand	0.097	0.903	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.096	0.904	0.000
E22.8 Other hyperfunction of pituitary gland	0.096	0.904	0.000
S27.3 Other injuries of lung	0.096	0.904	0.000
T19 Foreign body in genito-urinary tract	0.096	0.904	0.000
T15 Foreign body on external eye	0.096	0.904	0.000
T16 Foreign body in ear	0.096	0.904	0.000
S51.7 Multiple open wounds of forearm	0.095	0.904	0.000
S21.2 Open wound of back wall of thorax	0.095	0.904	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.095	0.904	0.000
S72.30 Fracture of shaft of femur (closed)	0.095	0.904	0.000
S31.4 Open wound of vagina and vulva	0.095	0.905	0.000
E22.1 Hyperprolactinaemia	0.095	0.905	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.095	0.905	0.000
T05 Traumatic amputations involving multiple body regions	0.095	0.905	0.000
T04 Crushing injuries involving multiple body regions	0.095	0.905	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.095	0.905	0.000
T01 Open wounds involving multiple body regions	0.095	0.905	0.000
T00 Superficial injuries involving multiple body regions	0.095	0.905	0.000
T07 Unspecified multiple injuries	0.095	0.905	0.000
S52.4 Fracture of shafts of both ulna and radius	0.095	0.905	0.000
S63.1 Dislocation finger	0.095	0.905	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.095	0.905	0.000
S63.5 Sprain and strain of wrist	0.095	0.905	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.095	0.905	0.000
S63.2 Multiple dislocations of fingers	0.095	0.905	0.000
S63.0 Dislocation of wrist	0.095	0.905	0.000
S79.8 Other specified injuries of hip and thigh	0.095	0.905	0.000
S79.7 Multiple injuries of hip and thigh	0.095	0.905	0.000
S91 Open wound of ankle and foot	0.094	0.906	0.000
S63.6 Sprain and strain of finger(s)	0.093	0.907	0.000
T93 Sequelae of injuries of lower limb	0.093	0.907	0.000
S62.1 Fracture of other carpal bone(s)	0.093	0.907	0.000
S06.3 Focal brain injury	0.093	0.907	0.000
E34.8 Other specified endocrine disorders	0.093	0.907	0.000
E34.5 Androgen resistance syndrome	0.093	0.907	0.000
E34.4 Constitutional tall stature	0.093	0.907	0.000
E34.3 Short stature, not elsewhere classified	0.093	0.907	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.093	0.907	0.000
E34.1 Other hypersecretion of intestinal hormones	0.093	0.907	0.000
T28 Burn and corrosion of other internal organs	0.092	0.907	0.000
T27 Burn and corrosion of respiratory tract	0.092	0.907	0.000
T26 Burn and corrosion confined to eye and adnexa	0.092	0.907	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.092	0.907	0.000
T34 Frostbite with tissue necrosis	0.092	0.907	0.000
T33 Superficial frostbite	0.092	0.907	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.092	0.907	0.000
S22.9 Fracture of bony thorax, part unspecified	0.092	0.908	0.000
S22.8 Fracture of other parts of bony thorax	0.092	0.908	0.000
S22.5 Flail chest	0.092	0.908	0.000
T32 Corrosions classified according to extent of body surface involved	0.092	0.908	0.000
T30 Burn and corrosion, body region unspecified	0.092	0.908	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations