TreeWAS – Variant ID: rs17201248

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.002	0.998
N40 Hyperplasia of prostate	0.732	0.268	0.000
J45.9 Asthma, unspecified	0.000	0.310	0.690
N40-N51 Diseases of male genital organs	0.677	0.323	0.000
E03 Other hypothyroidism	0.034	0.331	0.635
N42 Other disorders of prostate	0.639	0.361	0.000
Chapter XIV Diseases of the genitourinary system	0.607	0.393	0.000
# Top node	0.589	0.411	0.000
Chapter IX Diseases of the circulatory system	0.586	0.414	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.574	0.426	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.571	0.429	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.569	0.431	0.000
I83 Varicose veins of lower extremities	0.568	0.432	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.568	0.432	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.567	0.433	0.000
N20-N23 Urolithiasis	0.561	0.439	0.000
I26 Pulmonary embolism	0.559	0.441	0.000
M50-M54 Other dorsopathies	0.554	0.446	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.554	0.446	0.000
N42.2 Atrophy of prostate	0.551	0.449	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.549	0.451	0.000
N41 Inflammatory diseases of prostate	0.548	0.452	0.000
N42.9 Disorder of prostate, unspecified	0.547	0.453	0.000
I30-I52 Other forms of heart disease	0.538	0.462	0.000
N10-N16 Renal tubulo-interstitial diseases	0.536	0.464	0.000
N42.8 Other specified disorders of prostate	0.533	0.467	0.000
M54 Dorsalgia	0.532	0.468	0.000
Chapter VII Diseases of the eye and adnexa	0.531	0.469	0.000
O60-O75 Complications of labour and delivery	0.530	0.470	0.000
N21 Calculus of lower urinary tract	0.529	0.471	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.521	0.479	0.000
M70-M79 Other soft tissue disorders	0.518	0.482	0.000
I46 Cardiac arrest	0.510	0.490	0.000
N45 Orchitis and epididymitis	0.509	0.490	0.000
M51 Other intervertebral disk disorders	0.506	0.493	0.000
N21.0 Calculus in bladder	0.506	0.494	0.000
S90-S99 Injuries to the ankle and foot	0.506	0.494	0.000
S20-S29 Injuries to the thorax	0.501	0.499	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.500	0.500	0.000
M54.9 Dorsalgia, unspecified	0.494	0.506	0.000
J45 Asthma	0.008	0.513	0.479
N51 Disorders of male genital organs in diseases classified elsewhere	0.485	0.515	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.485	0.515	0.000
N46 Male infertility	0.485	0.515	0.000
N44 Torsion of testis	0.485	0.515	0.000
E03.8 Other specified hypothyroidism	0.025	0.520	0.455
E03.5 Myxoedema coma	0.025	0.520	0.455
E03.4 Atrophy of thyroid (acquired)	0.025	0.520	0.455
E03.3 Postinfectious hypothyroidism	0.025	0.520	0.455
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.025	0.520	0.455
E03.1 Congenital hypothyroidism without goitre	0.025	0.520	0.455
E03.0 Congenital hypothyroidism with diffuse goitre	0.025	0.520	0.455
M51.2 Other specified intervertebral disk displacement	0.479	0.521	0.000
M54.4 Lumbago with sciatica	0.478	0.522	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.478	0.522	0.000
I46.0 Cardiac arrest with successful resuscitation	0.477	0.523	0.000
S32 Fracture of lumbar spine and pelvis	0.477	0.523	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.476	0.524	0.000
N25-N29 Other disorders of kidney and ureter	0.475	0.525	0.000
N23 Unspecified renal colic	0.473	0.527	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.469	0.531	0.000
I45 Other conduction disorders	0.467	0.533	0.000
N41.0 Acute prostatitis	0.467	0.533	0.000
Chapter XX External causes of morbidity and mortality	0.467	0.533	0.000
I82 Other venous embolism and thrombosis	0.464	0.536	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.464	0.536	0.000
M79.6 Pain in limb	0.464	0.536	0.000
N50 Other disorders of male genital organs	0.460	0.540	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.459	0.541	0.000
N42.3 Dysplasia of prostate	0.458	0.542	0.000
N42.0 Calculus of prostate	0.458	0.542	0.000
M40-M43 Deforming dorsopathies	0.456	0.543	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.456	0.544	0.000
E00-E07 Disorders of thyroid gland	0.081	0.545	0.374
I87 Other disorders of veins	0.455	0.545	0.000
M86-M90 Other osteopathies	0.453	0.547	0.000
I10-I15 Hypertensive diseases	0.453	0.547	0.000
M79.7 Fibromyalgia	0.453	0.547	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.452	0.548	0.000
N42.1 Congestion and haemorrhage of prostate	0.451	0.548	0.000
T66-T78 Other and unspecified effects of external causes	0.451	0.549	0.000
N13 Obstructive and reflux uropathy	0.451	0.549	0.000
H30-H36 Disorders of choroid and retina	0.447	0.553	0.000
T00-T07 Injuries involving multiple body regions	0.447	0.553	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.445	0.555	0.000
H55-H59 Other disorders of eye and adnexa	0.443	0.557	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.441	0.558	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.441	0.559	0.000
Chapter VIII Diseases of the ear and mastoid process	0.441	0.559	0.000
N41.1 Chronic prostatitis	0.440	0.559	0.000
I44 Atrioventricular and left bundle-branch block	0.440	0.560	0.000
M80-M85 Disorders of bone density and structure	0.440	0.560	0.000
S70-S79 Injuries to the hip and thigh	0.440	0.560	0.000
M65-M68 Disorders of synovium and tendon	0.439	0.561	0.000
I71 Aortic aneurysm and dissection	0.438	0.562	0.000
O63 Long labour	0.434	0.566	0.000
S80-S89 Injuries to the knee and lower leg	0.434	0.566	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.431	0.568	0.000
S10-S19 Injuries to the neck	0.431	0.569	0.000
N99-N99 Other disorders of the genitourinary system	0.431	0.569	0.000
H53-H54 Visual disturbances and blindness	0.428	0.572	0.000
I49 Other cardiac arrhythmias	0.428	0.572	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.428	0.572	0.000
S92 Fracture of foot, except ankle	0.426	0.574	0.000
M91-M94 Chondropathies	0.425	0.574	0.000
T79-T79 Certain early complications of trauma	0.425	0.575	0.000
O72 Postpartum haemorrhage	0.425	0.575	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.422	0.577	0.000
I46.9 Cardiac arrest, unspecified	0.422	0.578	0.000
H33 Retinal detachments and breaks	0.422	0.578	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.421	0.579	0.000
I00-I02 Acute rheumatic fever	0.420	0.580	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.419	0.581	0.000
M79.79 Fibromyalgia (Site unspecified)	0.419	0.581	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.417	0.583	0.000
O62 Abnormalities of forces of labour	0.416	0.584	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.414	0.586	0.000
Chapter XXII Codes for special purposes	0.413	0.587	0.000
I45.1 Other and unspecified right bundle-branch block	0.413	0.587	0.000
S32.0 Fracture of lumbar vertebra	0.411	0.589	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.409	0.591	0.000
M60-M63 Disorders of muscles	0.409	0.591	0.000
M00-M03 Infectious arthropathies	0.409	0.591	0.000
T33-T35 Frostbite	0.408	0.592	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.408	0.592	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.408	0.592	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.408	0.592	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.408	0.592	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.407	0.593	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.407	0.593	0.000
I88 Nonspecific lymphadenitis	0.407	0.593	0.000
I81 Portal vein thrombosis	0.407	0.593	0.000
I28 Other diseases of pulmonary vessels	0.407	0.593	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.405	0.595	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.405	0.595	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.404	0.595	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.403	0.597	0.000
H43-H45 Disorders of vitreous body and globe	0.403	0.597	0.000
S91 Open wound of ankle and foot	0.402	0.598	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.402	0.598	0.000
S27 Injury of other and unspecified intrathoracic organs	0.402	0.598	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.401	0.599	0.000
O64.1 Obstructed labour due to breech presentation	0.400	0.599	0.000
H33.2 Serous retinal detachment	0.400	0.600	0.000
M53 Other dorsopathies, not elsewhere classified	0.398	0.602	0.000
J40-J47 Chronic lower respiratory diseases	0.016	0.603	0.381
I31 Other diseases of pericardium	0.396	0.604	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.395	0.605	0.000
S32.5 Fracture of pubis	0.395	0.605	0.000
O85-O92 Complications predominantly related to the puerperium	0.394	0.606	0.000
S99 Other and unspecified injuries of ankle and foot	0.393	0.607	0.000
N41.8 Other inflammatory diseases of prostate	0.393	0.607	0.000
N41.3 Prostatocystitis	0.393	0.607	0.000
N41.2 Abscess of prostate	0.393	0.607	0.000
I12 Hypertensive renal disease	0.393	0.607	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.392	0.607	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.392	0.608	0.000
M79.2 Neuralgia and neuritis, unspecified	0.392	0.608	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.392	0.608	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.392	0.608	0.000
S22.4 Multiple fractures of ribs	0.391	0.608	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.391	0.609	0.000
I82.8 Embolism and thrombosis of other specified veins	0.390	0.610	0.000
I51 Complications and ill-defined descriptions of heart disease	0.390	0.610	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.390	0.610	0.000
I30 Acute pericarditis	0.389	0.611	0.000
H10-H13 Disorders of conjunctiva	0.389	0.611	0.000
O73 Retained placenta and membranes, without haemorrhage	0.387	0.612	0.000
I44.1 Atrioventricular block, second degree	0.387	0.612	0.000
I44.0 Atrioventricular block, first degree	0.387	0.613	0.000
N43 Hydrocele and spermatocele	0.386	0.614	0.000
I52 Other heart disorders in diseases classified elsewhere	0.386	0.614	0.000
I48 Atrial fibrillation and flutter	0.386	0.614	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.386	0.614	0.000
I41 Myocarditis in diseases classified elsewhere	0.386	0.614	0.000
I40 Acute myocarditis	0.386	0.614	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.386	0.614	0.000
I37 Pulmonary valve disorders	0.386	0.614	0.000
I36 Nonrheumatic tricuspid valve disorders	0.386	0.614	0.000
I32 Pericarditis in diseases classified elsewhere	0.386	0.614	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.384	0.616	0.000
N15 Other renal tubulo-interstitial diseases	0.384	0.616	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.384	0.616	0.000
N11 Chronic tubulo-interstitial nephritis	0.384	0.616	0.000
N10 Acute tubulo-interstitial nephritis	0.384	0.616	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.384	0.616	0.000
I05-I09 Chronic rheumatic heart diseases	0.383	0.617	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.382	0.617	0.001
I50 Heart failure	0.382	0.618	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.382	0.618	0.000
M54.1 Radiculopathy	0.381	0.619	0.000
M54.8 Other dorsalgia	0.381	0.619	0.000
M54.6 Pain in thoracic spine	0.381	0.619	0.000
M54.0 Panniculitis affecting regions of neck and back	0.381	0.619	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.381	0.619	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.380	0.619	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.380	0.620	0.000
O74 Complications of anaesthesia during labour and delivery	0.380	0.620	0.000
O71 Other obstetric trauma	0.380	0.620	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.380	0.620	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.380	0.620	0.000
O61 Failed induction of labour	0.380	0.620	0.000
O60 Preterm delivery	0.380	0.620	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.379	0.621	0.000
N21.8 Other lower urinary tract calculus	0.379	0.621	0.000
N21.1 Calculus in urethra	0.379	0.621	0.000
M79.64 Pain in limb (Hand)	0.379	0.621	0.000
N13.3 Other and unspecified hydronephrosis	0.379	0.621	0.000
T92 Sequelae of injuries of upper limb	0.379	0.621	0.000
S50-S59 Injuries to the elbow and forearm	0.378	0.622	0.000
M54.5 Low back pain	0.378	0.622	0.000
N00-N08 Glomerular diseases	0.377	0.623	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.377	0.623	0.000
T93 Sequelae of injuries of lower limb	0.376	0.624	0.000
I86 Varicose veins of other sites	0.376	0.624	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.376	0.624	0.000
M54.3 Sciatica	0.374	0.626	0.000
I72 Other aneurysm	0.374	0.626	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.374	0.626	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.373	0.626	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.373	0.626	0.000
S37 Injury of urinary and pelvic organs	0.373	0.626	0.000
S36 Injury of intra-abdominal organs	0.373	0.626	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.373	0.626	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.373	0.626	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.373	0.626	0.000
S31 Open wound of abdomen, lower back and pelvis	0.373	0.626	0.000
M45-M49 Spondylopathies	0.373	0.627	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.043	0.627	0.330
M79.60 Pain in limb (Multiple sites)	0.373	0.627	0.000
M76 Enthesopathies of lower limb, excluding foot	0.372	0.628	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.372	0.628	0.000
H49 Paralytic strabismus	0.371	0.628	0.000
M72 Fibroblastic disorders	0.371	0.629	0.000
M77 Other enthesopathies	0.371	0.629	0.000
O66 Other obstructed labour	0.370	0.630	0.000
I85 Oesophageal varices	0.370	0.630	0.000
M89 Other disorders of bone	0.369	0.630	0.000
O16 Unspecified maternal hypertension	0.369	0.631	0.000
M43 Other deforming dorsopathies	0.369	0.631	0.000
J44 Other chronic obstructive pulmonary disease	0.002	0.631	0.367
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.369	0.631	0.000
Y86 Sequelae of other accidents	0.369	0.631	0.000
M71 Other bursopathies	0.367	0.633	0.000
N50.8 Other specified disorders of male genital organs	0.367	0.633	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.367	0.633	0.000
I33 Acute and subacute endocarditis	0.366	0.634	0.000
T78 Adverse effects, not elsewhere classified	0.366	0.634	0.000
I46.1 Sudden cardiac death, so described	0.366	0.634	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.365	0.635	0.000
H57 Other disorders of eye and adnexa	0.364	0.635	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.364	0.636	0.000
M79.5 Residual foreign body in soft tissue	0.364	0.636	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.364	0.636	0.000
M51.3 Other specified intervertebral disk degeneration	0.363	0.637	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.363	0.637	0.000
M51.9 Intervertebral disk disorder, unspecified	0.363	0.637	0.000
M51.8 Other specified intervertebral disk disorders	0.363	0.637	0.000
M51.4 Schmorl's nodes	0.363	0.637	0.000
S22.40 Multiple fractures of ribs (closed)	0.363	0.637	0.000
S98 Traumatic amputation of ankle and foot	0.363	0.637	0.000
S97 Crushing injury of ankle and foot	0.363	0.637	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.363	0.637	0.000
S95 Injury of blood vessels at ankle and foot level	0.363	0.637	0.000
S94 Injury of nerves at ankle and foot level	0.363	0.637	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.363	0.637	0.000
S90 Superficial injury of ankle and foot	0.363	0.637	0.000
S40-S49 Injuries to the shoulder and upper arm	0.362	0.638	0.000
M79.69 Pain in limb (Site unspecified)	0.362	0.638	0.000
I74 Arterial embolism and thrombosis	0.362	0.638	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.361	0.639	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.360	0.640	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.360	0.640	0.000
M65 Synovitis and tenosynovitis	0.360	0.640	0.000
T02 Fractures involving multiple body regions	0.359	0.640	0.000
S29 Other and unspecified injuries of thorax	0.359	0.641	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.359	0.641	0.000
S26 Injury of heart	0.359	0.641	0.000
S25 Injury of blood vessels of thorax	0.359	0.641	0.000
S24 Injury of nerves and spinal cord at thorax level	0.359	0.641	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.359	0.641	0.000
S21 Open wound of thorax	0.359	0.641	0.000
S20 Superficial injury of thorax	0.359	0.641	0.000
M79.9 Soft tissue disorder, unspecified	0.359	0.641	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.359	0.641	0.000
M79.3 Panniculitis, unspecified	0.359	0.641	0.000
M79.1 Myalgia	0.359	0.641	0.000
I70 Atherosclerosis	0.359	0.641	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.359	0.641	0.000
T90 Sequelae of injuries of head	0.358	0.641	0.000
O80-O84 Delivery	0.358	0.642	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.357	0.643	0.000
H52 Disorders of refraction and accommodation	0.357	0.643	0.000
N48 Other disorders of penis	0.357	0.643	0.000
M54.2 Cervicalgia	0.357	0.643	0.000
I42 Cardiomyopathy	0.357	0.643	0.000
M80 Osteoporosis with pathological fracture	0.357	0.643	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.357	0.643	0.000
H90-H95 Other disorders of ear	0.357	0.643	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.356	0.644	0.000
M79.67 Pain in limb (Ankle and foot)	0.356	0.644	0.000
I87.1 Compression of vein	0.355	0.645	0.000
O63.0 Prolonged first stage (of labour)	0.355	0.645	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.355	0.645	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.355	0.645	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.355	0.645	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.355	0.645	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.355	0.645	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.355	0.645	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.355	0.645	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.353	0.646	0.000
H54 Blindness and low vision	0.353	0.647	0.000
S71 Open wound of hip and thigh	0.352	0.648	0.000
O72.1 Other immediate postpartum haemorrhage	0.352	0.648	0.000
V10-V19 Pedal cyclist injured in transport accident	0.350	0.650	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.350	0.650	0.000
H50 Other strabismus	0.350	0.650	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.350	0.650	0.000
J45.8 Mixed asthma	0.006	0.651	0.343
J45.1 Nonallergic asthma	0.006	0.651	0.343
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.349	0.651	0.000
I45.9 Conduction disorder, unspecified	0.349	0.651	0.000
Q50-Q56 Congenital malformations of genital organs	0.349	0.651	0.000
Q00-Q07 Congenital malformations of the nervous system	0.348	0.651	0.000
H60-H62 Diseases of external ear	0.348	0.651	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.348	0.652	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.348	0.652	0.000
N49.2 Inflammatory disorders of scrotum	0.348	0.652	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.348	0.652	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.348	0.652	0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.348	0.652	0.000
N51.2 Balanitis in diseases classified elsewhere	0.348	0.652	0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.348	0.652	0.000
N51.0 Disorders of prostate in diseases classified elsewhere	0.348	0.652	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.347	0.653	0.000
S92.0 Fracture of calcaneus	0.345	0.655	0.000
I31.3 Pericardial effusion (noninflammatory)	0.344	0.655	0.000
L60-L75 Disorders of skin appendages	0.344	0.656	0.000
H55 Nystagmus and other irregular eye movements	0.344	0.656	0.000
M79.8 Other specified soft tissue disorders	0.344	0.656	0.000
O62.3 Precipitate labour	0.343	0.657	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.343	0.657	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.343	0.657	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.343	0.657	0.000
M54.44 Lumbago with sciatica-Thoracic	0.343	0.657	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.343	0.657	0.000
M54.42 Lumbago with sciatica-Cervical	0.343	0.657	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.343	0.657	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.343	0.657	0.000
T98 Sequelae of other and unspecified effects of external causes	0.343	0.657	0.000
T95 Sequelae of burns, corrosions and frostbite	0.343	0.657	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.343	0.657	0.000
T91 Sequelae of injuries of neck and trunk	0.343	0.657	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.343	0.657	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.343	0.657	0.000
I11 Hypertensive heart disease	0.342	0.658	0.000
N17-N19 Renal failure	0.342	0.658	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.342	0.658	0.000
S32.3 Fracture of ilium	0.342	0.658	0.000
S32.2 Fracture of coccyx	0.342	0.658	0.000
S32.1 Fracture of sacrum	0.342	0.658	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.342	0.658	0.000
M79.62 Pain in limb (Upper arm)	0.341	0.659	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.341	0.659	0.000
N27 Small kidney of unknown cause	0.341	0.659	0.000
N25 Disorders resulting from impaired renal tubular function	0.341	0.659	0.000
N26 Unspecified contracted kidney	0.341	0.659	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.341	0.659	0.000
S92.3 Fracture of metatarsal bone	0.341	0.659	0.000
O63.9 Long labour, unspecified	0.339	0.661	0.000
X60-X84 Intentional self-harm	0.339	0.661	0.000
S82 Fracture of lower leg, including ankle	0.339	0.661	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.338	0.662	0.000
I27 Other pulmonary heart diseases	0.338	0.662	0.000
I49.4 Other and unspecified premature depolarisation	0.338	0.662	0.000
W20-W49 Exposure to inanimate mechanical forces	0.337	0.663	0.000
I49.5 Sick sinus syndrome	0.337	0.663	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.337	0.663	0.000
M05-M14 Inflammatory polyarthropathies	0.337	0.663	0.000
I50.9 Heart failure, unspecified	0.337	0.663	0.000
S32.50 Fracture of pubis (closed)	0.336	0.664	0.000
S30.1 Contusion of abdominal wall	0.336	0.664	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.336	0.664	0.000
Q80-Q89 Other congenital malformations	0.336	0.664	0.000
Q35-Q37 Cleft lip and cleft palate	0.336	0.664	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.336	0.664	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.336	0.664	0.000
I12.9 Hypertensive renal disease without renal failure	0.336	0.664	0.000
M41 Scoliosis	0.335	0.664	0.000
I38 Endocarditis, valve unspecified	0.335	0.665	0.000
I45.8 Other specified conduction disorders	0.335	0.665	0.000
I45.5 Other specified heart block	0.335	0.665	0.000
I45.4 Nonspecific intraventricular block	0.335	0.665	0.000
I45.3 Trifascicular block	0.335	0.665	0.000
I45.2 Bifascicular block	0.335	0.665	0.000
I45.0 Right fascicular block	0.335	0.665	0.000
S32.4 Fracture of acetabulum	0.335	0.665	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.335	0.665	0.000
Y35-Y36 Legal intervention and operations of war	0.335	0.665	0.000
Y10-Y34 Event of undetermined intent	0.335	0.665	0.000
Y00-Y09 Assault	0.335	0.665	0.000
X85-X99 Assault	0.335	0.665	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.335	0.665	0.000
X50-X57 Overexertion, travel and privation	0.335	0.665	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.335	0.665	0.000
X30-X39 Exposure to forces of nature	0.335	0.665	0.000
X20-X29 Contact with venomous animals and plants	0.335	0.665	0.000
X10-X19 Contact with heat and hot substances	0.335	0.665	0.000
X00-X09 Exposure to smoke, fire and flames	0.335	0.665	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.335	0.665	0.000
W75-W84 Other accidental threats to breathing	0.335	0.665	0.000
W65-W74 Accidental drowning and submersion	0.335	0.665	0.000
W50-W64 Exposure to animate mechanical forces	0.335	0.665	0.000
V98-V99 Other and unspecified transport accidents	0.335	0.665	0.000
V95-V97 Air and space transport accidents	0.335	0.665	0.000
V90-V94 Water transport accidents	0.335	0.665	0.000
V80-V89 Other land transport accidents	0.335	0.665	0.000
V70-V79 Bus occupant injured in transport accident	0.335	0.665	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.335	0.665	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.335	0.665	0.000
V40-V49 Car occupant injured in transport accident	0.335	0.665	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.335	0.665	0.000
V01-V09 Pedestrian injured in transport accident	0.335	0.665	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.334	0.666	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.333	0.667	0.000
I82.3 Embolism and thrombosis of renal vein	0.333	0.667	0.000
I82.2 Embolism and thrombosis of vena cava	0.333	0.667	0.000
I82.1 Thrombophlebitis migrans	0.333	0.667	0.000
I82.0 Budd-Chiari syndrome	0.333	0.667	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.333	0.667	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.333	0.667	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.333	0.667	0.000
O64.5 Obstructed labour due to compound presentation	0.333	0.667	0.000
O64.4 Obstructed labour due to shoulder presentation	0.333	0.667	0.000
O64.3 Obstructed labour due to brow presentation	0.333	0.667	0.000
O64.2 Obstructed labour due to face presentation	0.333	0.667	0.000
M79.68 Pain in limb (Other)	0.333	0.667	0.000
M79.63 Pain in limb (Forearm)	0.333	0.667	0.000
M79.61 Pain in limb (Shoulder region)	0.333	0.667	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.332	0.667	0.000
N13.4 Hydroureter	0.332	0.667	0.000
S12 Fracture of neck	0.332	0.668	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.331	0.669	0.000
H34 Retinal vascular occlusions	0.331	0.669	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.331	0.669	0.000
S27.0 Traumatic pneumothorax	0.330	0.670	0.000
O00-O08 Pregnancy with abortive outcome	0.330	0.670	0.000
N50.9 Disorder of male genital organs, unspecified	0.330	0.670	0.000
N50.0 Atrophy of testis	0.330	0.670	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.670	0.330
M87 Osteonecrosis	0.330	0.670	0.000
O15 Eclampsia	0.329	0.671	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.329	0.671	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.329	0.671	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.329	0.671	0.000
L20-L30 Dermatitis and eczema	0.328	0.671	0.000
I45.6 Preexcitation syndrome	0.328	0.672	0.000
M84 Disorders of continuity of bone	0.328	0.672	0.000
S91.3 Open wound of other parts of foot	0.328	0.672	0.000
V20-V29 Motorcycle rider injured in transport accident	0.328	0.672	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.672	0.328
M42 Spinal osteochondrosis	0.327	0.672	0.000
M40 Kyphosis and lordosis	0.327	0.672	0.000
Q60-Q64 Congenital malformations of the urinary system	0.327	0.672	0.000
H51 Other disorders of binocular movement	0.327	0.673	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.327	0.673	0.000
E06 Thyroiditis	0.058	0.673	0.268
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.058	0.673	0.268
E00 Congenital iodine-deficiency syndrome	0.058	0.673	0.268
E02 Subclinical iodine-deficiency hypothyroidism	0.058	0.673	0.268
I87.9 Disorder of vein, unspecified	0.326	0.674	0.000
I87.8 Other specified disorders of veins	0.326	0.674	0.000
I87.0 Postphlebitic syndrome	0.326	0.674	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.325	0.675	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.325	0.675	0.000
N28.1 Cyst of kidney, acquired	0.325	0.675	0.000
I49.0 Ventricular fibrillation and flutter	0.325	0.675	0.000
N60-N64 Disorders of breast	0.325	0.675	0.000
M90 Osteopathies in diseases classified elsewhere	0.325	0.675	0.000
I15 Secondary hypertension	0.325	0.675	0.000
I13 Hypertensive heart and renal disease	0.325	0.675	0.000
M79.78 Fibromyalgia (Other)	0.325	0.675	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.325	0.675	0.000
M79.76 Fibromyalgia (Lower leg)	0.325	0.675	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.325	0.675	0.000
M79.74 Fibromyalgia (Hand)	0.325	0.675	0.000
M79.73 Fibromyalgia (Forearm)	0.325	0.675	0.000
M79.72 Fibromyalgia (Upper arm)	0.325	0.675	0.000
M79.71 Fibromyalgia (Shoulder region)	0.325	0.675	0.000
M79.70 Fibromyalgia (Multiple sites)	0.325	0.675	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.325	0.675	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.324	0.676	0.000
T75 Effects of other external causes	0.323	0.676	0.000
T74 Maltreatment syndromes	0.323	0.676	0.000
T73 Effects of other deprivation	0.323	0.676	0.000
T70 Effects of air pressure and water pressure	0.323	0.676	0.000
T69 Other effects of reduced temperature	0.323	0.676	0.000
T67 Effects of heat and light	0.323	0.676	0.000
T71 Asphyxiation	0.323	0.676	0.000
T68 Hypothermia	0.323	0.676	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations