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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17202407
log Bayes Factor = 76.3635
Chromosome 6   position 32,361,613  (GRCh37) Explore rs17202407 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
C44.7 Skin of lower limb, including hip
0.999 0.001 0.000
K50-K52 Noninfective enteritis and colitis
0.999 0.001 0.000
K50 Crohn's disease [regional enteritis]
0.999 0.001 0.000
K50.1 Crohn's disease of large intestine
0.998 0.002 0.000
Z93.2 Ileostomy status
0.997 0.003 0.000
C44.4 Skin of scalp and neck
0.996 0.004 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.007 0.993
D86 Sarcoidosis
0.000 0.007 0.993
K51.4 Pseudopolyposis of colon
0.990 0.010 0.000
E10.1 With ketoacidosis
0.000 0.010 0.990
E10.3 With ophthalmic complications
0.000 0.012 0.988
C44.2 Skin of ear and external auricular canal
0.984 0.016 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.982 0.018 0.000
D86.0 Sarcoidosis of lung
0.000 0.018 0.982
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.974 0.026 0.000
C44.6 Skin of upper limb, including shoulder
0.969 0.031 0.000
C44.5 Skin of trunk
0.968 0.032 0.000
K51.8 Other ulcerative colitis
0.960 0.040 0.000
C44.0 Skin of lip
0.956 0.044 0.000
K51.2 Ulcerative (chronic) proctitis
0.951 0.049 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.937 0.063 0.000
K50.9 Crohn's disease, unspecified
0.932 0.068 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.920 0.080 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.084 0.916
C83.3 Large cell (diffuse)
0.915 0.085 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.907 0.093 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.104 0.896
C82.0 Small cleaved cell, follicular
0.896 0.104 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.889 0.111 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.112 0.888
D50-D53 Nutritional anaemias
0.000 0.113 0.887
E10-E14 Diabetes mellitus
0.000 0.115 0.885
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.116 0.884
D80-D89 Certain disorders involving the immune mechanism
0.000 0.125 0.875
D50 Iron deficiency anaemia
0.000 0.134 0.866
D50.9 Iron deficiency anaemia, unspecified
0.000 0.136 0.864
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.144 0.856
E16.2 Hypoglycaemia, unspecified
0.000 0.157 0.843
E10.8 With unspecified complications
0.000 0.158 0.842
E16 Other disorders of pancreatic internal secretion
0.000 0.159 0.841
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.162 0.838
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.163 0.837
K51.5 Mucosal proctocolitis
0.836 0.164 0.000
K52 Other non-infective gastro-enteritis and colitis
0.823 0.177 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.182 0.818
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.817 0.183 0.000
C44.1 Skin of eyelid, including canthus
0.808 0.192 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.209 0.791
C82.3 Follicular lymphoma grade IIIa
0.785 0.215 0.000
E27 Other disorders of adrenal gland
0.000 0.216 0.784
E27.1 Primary adrenocortical insufficiency
0.000 0.219 0.781
E10.0 With coma
0.000 0.226 0.774
E10.4 With neurological complications
0.000 0.228 0.772
C44.9 Malignant neoplasm of skin, unspecified
0.765 0.235 0.000
K90 Intestinal malabsorption
0.000 0.244 0.756
E10.6 With other specified complications
0.000 0.246 0.754
K51.3 Ulcerative (chronic) rectosigmoiditis
0.748 0.252 0.000
K50.8 Other Crohn's disease
0.741 0.259 0.000
K52.1 Toxic gastro-enteritis and colitis
0.733 0.267 0.000
C83.1 Small cleaved cell (diffuse)
0.726 0.273 0.000
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E10.2 With renal complications
0.000 0.286 0.714
D86.3 Sarcoidosis of skin
0.000 0.288 0.712
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.288 0.712
K51.0 Ulcerative (chronic) enterocolitis
0.709 0.291 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.705 0.295 0.000
C82.6 Cutaneous follicle centre lymphoma
0.698 0.302 0.000
C82.5 Diffuse follicle centre lymphoma
0.698 0.302 0.000
C82.4 Follicular lymphoma grade IIIb
0.698 0.302 0.000
D52 Folate deficiency anaemia
0.000 0.304 0.695
C81 Hodgkin's disease
0.694 0.306 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.694 0.306 0.000
E14 Unspecified diabetes mellitus
0.000 0.313 0.687
C85.1 B-cell lymphoma, unspecified
0.686 0.314 0.000
E22 Hyperfunction of pituitary gland
0.000 0.315 0.685
K52.3 Indeterminate colitis
0.684 0.316 0.000
E16.1 Other hypoglycaemia
0.000 0.321 0.678
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.672 0.328 0.000
C94 Other leukaemias of specified cell type
0.672 0.328 0.000
C93 Monocytic leukaemia
0.672 0.328 0.000
C86 Other specified types of T/NK-cell lymphoma
0.672 0.328 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.330 0.670
C84 Peripheral and cutaneous T-cell lymphomas
0.668 0.332 0.000
C95 Leukaemia of unspecified cell type
0.662 0.338 0.000
C83.6 Undifferentiated (diffuse)
0.660 0.340 0.000
C83.5 Lymphoblastic (diffuse)
0.660 0.340 0.000
C83.4 Immunoblastic (diffuse)
0.660 0.340 0.000
C83.2 Mixed small and large cell (diffuse)
0.660 0.340 0.000
E13 Other specified diabetes mellitus
0.000 0.341 0.659
C82.2 Large cell, follicular
0.653 0.346 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.650 0.350 0.000
C85.0 Lymphosarcoma
0.650 0.350 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.350 0.649
K51.1 Ulcerative (chronic) ileocolitis
0.640 0.360 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.638 0.362 0.000
E10.5 With peripheral circulatory complications
0.000 0.363 0.637
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.363 0.636
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.363 0.636
D51.2 Transcobalamin II deficiency
0.000 0.363 0.636
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.363 0.636
E12 Malnutrition-related diabetes mellitus
0.000 0.366 0.634
C83.7 Burkitt's tumour
0.633 0.367 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.368 0.632
D82 Immunodeficiency associated with other major defects
0.000 0.373 0.627
D81 Combined immunodeficiencies
0.000 0.373 0.627
D50.1 Sideropenic dysphagia
0.000 0.379 0.621
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.381 0.619
E27.2 Addisonian crisis
0.000 0.383 0.617
E24 Cushing's syndrome
0.000 0.383 0.617
D53 Other nutritional anaemias
0.000 0.385 0.615
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.397 0.603
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.397 0.603
E16.4 Abnormal secretion of gastrin
0.000 0.397 0.603
E16.3 Increased secretion of glucagon
0.000 0.397 0.603
K90.9 Intestinal malabsorption, unspecified
0.000 0.397 0.603
C88 Malignant immunoproliferative diseases
0.601 0.399 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.601 0.399 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.399 0.601
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.405 0.595
C90 Multiple myeloma and malignant plasma cell neoplasms
0.584 0.416 0.000
E14.9 Without complications
0.000 0.418 0.582
D55-D59 Haemolytic anaemias
0.000 0.427 0.573
K90.8 Other intestinal malabsorption
0.000 0.427 0.573
E20 Hypoparathyroidism
0.000 0.428 0.572
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.433 0.567
E32 Diseases of thymus
0.000 0.433 0.567
E31 Polyglandular dysfunction
0.000 0.433 0.567
E30 Disorders of puberty, not elsewhere classified
0.000 0.433 0.567
E25 Adrenogenital disorders
0.000 0.433 0.567
C81.1 Nodular sclerosis
0.566 0.434 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.437 0.563
E27.5 Adrenomedullary hyperfunction
0.000 0.438 0.562
E27.0 Other adrenocortical overactivity
0.000 0.438 0.562
D52.9 Folate deficiency anaemia, unspecified
0.000 0.441 0.559
D83 Common variable immunodeficiency
0.000 0.451 0.549
C85.7 Other specified types of non-Hodgkin's lymphoma
0.548 0.452 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.458 0.542
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.458 0.542
K90.1 Tropical sprue
0.000 0.458 0.542
E40-E46 Malnutrition
0.000 0.459 0.541
D80 Immunodeficiency with predominantly antibody defects
0.000 0.461 0.539
C43-C44 Melanoma and other malignant neoplasms of skin
0.536 0.464 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.532 0.468 0.000
C81.2 Mixed cellularity
0.528 0.472 0.000
C81.0 Lymphocytic predominance
0.524 0.476 0.000
E34 Other endocrine disorders
0.000 0.478 0.522
E27.8 Other specified disorders of adrenal gland
0.000 0.479 0.521
E14.3 With ophthalmic complications
0.000 0.484 0.516
C95.0 Acute leukaemia of unspecified cell type
0.514 0.486 0.000
E21.0 Primary hyperparathyroidism
0.000 0.488 0.512
E22.0 Acromegaly and pituitary gigantism
0.000 0.490 0.510
D84 Other immunodeficiencies
0.000 0.492 0.507
E22.1 Hyperprolactinaemia
0.000 0.496 0.504
D52.8 Other folate deficiency anaemias
0.000 0.501 0.499
D52.1 Drug-induced folate deficiency anaemia
0.000 0.501 0.499
D52.0 Dietary folate deficiency anaemia
0.000 0.501 0.499
E13.9 Without complications
0.000 0.502 0.498
C81.7 Other Hodgkin's disease
0.498 0.502 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.498 0.502 0.000
C81.3 Lymphocytic depletion
0.498 0.502 0.000
E14.8 With unspecified complications
0.000 0.507 0.493
E14.7 With multiple complications
0.000 0.507 0.493
E14.2 Withrenal complications
0.000 0.507 0.493
E14.1 With ketoacidosis
0.000 0.507 0.493
E14.0 With coma
0.000 0.507 0.493
E24.9 Cushing's syndrome, unspecified
0.000 0.508 0.492
C84.0 Mycosis fungoides
0.491 0.508 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.509 0.491
E22.8 Other hyperfunction of pituitary gland
0.000 0.509 0.491
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.514 0.486
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.482 0.518 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.482 0.518 0.000
C86.4 Blastic NK-cell lymphoma
0.482 0.518 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.482 0.518 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.482 0.518 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.482 0.518 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.482 0.518 0.000
C93.9 Monocytic leukaemia, unspecified
0.482 0.518 0.000
C93.7 Other monocytic leukaemia
0.482 0.518 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.482 0.518 0.000
C93.2 Subacute monocytic leukaemia
0.482 0.518 0.000
C93.1 Chronic monocytic leukaemia
0.482 0.518 0.000
C93.0 Acute monocytic leukaemia
0.482 0.518 0.000
C94.7 Other specified leukaemias
0.482 0.518 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.482 0.518 0.000
C94.5 Acute myelofibrosis
0.482 0.518 0.000
C94.4 Acute panmyelosis
0.482 0.518 0.000
C94.3 Mast cell leukaemia
0.482 0.518 0.000
C94.2 Acute megakaryoblastic leukaemia
0.482 0.518 0.000
C94.1 Chronic erythraemia
0.482 0.518 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.482 0.518 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.482 0.518 0.000
C96.8 Histiocytic sarcoma
0.482 0.518 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.482 0.518 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.482 0.518 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.482 0.518 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.482 0.518 0.000
C96.3 True histiocytic lymphoma
0.482 0.518 0.000
C96.2 Malignant mast cell tumour
0.482 0.518 0.000
C96.1 Malignant histiocytosis
0.482 0.518 0.000
C96.0 Letterer-Siwe disease
0.482 0.518 0.000
C84.4 Peripheral T-cell lymphoma
0.482 0.518 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.479 0.521 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.479 0.521 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.479 0.521 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.479 0.521 0.000
C84.3 Lymphoepithelioid lymphoma
0.479 0.521 0.000
C84.2 T-zone lymphoma
0.479 0.521 0.000
C84.1 Sezary's diease
0.479 0.521 0.000
E14.6 With other specified complications
0.000 0.523 0.477
E29 Testicular dysfunction
0.000 0.524 0.476
C95.7 Other leukaemia of unspecified cell type
0.474 0.525 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.474 0.525 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.474 0.525 0.000
E13.8 With unspecified complications
0.000 0.527 0.473
E13.7 With multiple complications
0.000 0.527 0.473
E13.6 With other specified complications
0.000 0.527 0.473
E13.5 With peripheral circulatory complications
0.000 0.527 0.473
E13.4 With neurological complications
0.000 0.527 0.473
E13.3 With ophthalmic complications
0.000 0.527 0.473
E13.2 With renal complications
0.000 0.527 0.473
E13.1 With ketoacidosis
0.000 0.527 0.473
E13.0 With coma
0.000 0.527 0.473
E14.5 With peripheral circulatory complications
0.000 0.528 0.472
D59 Acquired haemolytic anaemia
0.000 0.528 0.472
E65-E68 Obesity and other hyperalimentation
0.000 0.542 0.458
C84.5 Other and unspecified T-cell lymphomas
0.457 0.543 0.000
E12.9 Without complications
0.000 0.545 0.455
E12.8 With unspecified complications
0.000 0.545 0.455
E12.7 With multiple complications
0.000 0.545 0.455
E12.6 With other specified complications
0.000 0.545 0.455
E12.5 With peripheral circulatory complications
0.000 0.545 0.455
E12.4 With neurological complications
0.000 0.545 0.455
E12.3 With ophthalmic complications
0.000 0.545 0.455
E12.2 With renal complications
0.000 0.545 0.455
E12.1 With ketoacidosis
0.000 0.545 0.455
E12.0 With coma
0.000 0.545 0.455
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.547 0.453
E21.4 Other specified disorders of parathyroid gland
0.000 0.547 0.453
E21.2 Other hyperparathyroidism
0.000 0.547 0.453
D81.9 Combined immunodeficiency, unspecified
0.000 0.550 0.450
D81.8 Other combined immunodeficiencies
0.000 0.550 0.450
D81.7 Major histocompatibility complex class II deficiency
0.000 0.550 0.450
D81.6 Major histocompatibility complex class I deficiency
0.000 0.550 0.450
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.550 0.450
D81.4 Nezelof's syndrome
0.000 0.550 0.450
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.550 0.450
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.550 0.450
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.550 0.450
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.550 0.450
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.550 0.450
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.550 0.450
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.550 0.450
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.550 0.450
D82.2 Immunodeficiency with short-limbed stature
0.000 0.550 0.450
D82.1 Di George's syndrome
0.000 0.550 0.450
D82.0 Wiskott-Aldrich syndrome
0.000 0.550 0.450
K52.0 Gastro-enteritis and colitis due to radiation
0.448 0.552 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.556 0.444
E24.8 Other Cushing's syndrome
0.000 0.558 0.442
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.558 0.442
E24.3 Ectopic ACTH syndrome
0.000 0.558 0.442
E24.2 Drug-induced Cushing's syndrome
0.000 0.558 0.442
E24.1 Nelson's syndrome
0.000 0.558 0.442
E24.0 Pituitary-dependent Cushing's disease
0.000 0.558 0.442
D53.8 Other specified nutritional anaemias
0.000 0.559 0.441
D53.2 Scorbutic anaemia
0.000 0.559 0.441
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.559 0.441
D53.0 Protein deficiency anaemia
0.000 0.559 0.441
E14.4 With neurological complications
0.000 0.560 0.440
E34.0 Carcinoid syndrome
0.000 0.565 0.435
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.568 0.432
C88.9 Malignant immunoproliferative disease, unspecified
0.431 0.569 0.000
C88.7 Other malignant immunoproliferative diseases
0.431 0.569 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.431 0.569 0.000
C88.3 Immunoproliferative small intestinal disease
0.431 0.569 0.000
C88.2 Gamma heavy chain disease
0.431 0.569 0.000
C88.1 Alpha heavy chain disease
0.431 0.569 0.000
E50-E64 Other nutritional deficiencies
0.000 0.570 0.430
C91 Lymphoid leukaemia
0.429 0.570 0.002
E21.3 Hyperparathyroidism, unspecified
0.000 0.577 0.423
D53.9 Nutritional anaemia, unspecified
0.000 0.580 0.420
C90.3 Solitary plasmacytoma
0.419 0.581 0.000
C90.1 Plasma cell leukaemia
0.419 0.581 0.000
C83.0 Small cell (diffuse)
0.415 0.584 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.585 0.415
C95.9 Leukaemia, unspecified
0.412 0.588 0.000
D57 Sickle-cell disorders
0.000 0.589 0.411
D55 Anaemia due to enzyme disorders
0.000 0.589 0.411
E20.8 Other hypoparathyroidism
0.000 0.590 0.410
E20.1 Pseudohypoparathyroidism
0.000 0.590 0.410
E20.0 Idiopathic hypoparathyroidism
0.000 0.590 0.410
C92 Myeloid leukaemia
0.407 0.592 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.593 0.407
E25.8 Other adrenogenital disorders
0.000 0.593 0.407
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.593 0.407
E30.9 Disorder of puberty, unspecified
0.000 0.593 0.407
E30.8 Other disorders of puberty
0.000 0.593 0.407
E30.1 Precocious puberty
0.000 0.593 0.407
E30.0 Delayed puberty
0.000 0.593 0.407
E31.9 Polyglandular dysfunction, unspecified
0.000 0.593 0.407
E31.8 Other polyglandular dysfunction
0.000 0.593 0.407
E31.1 Polyglandular hyperfunction
0.000 0.593 0.407
E31.0 Autoimmune polyglandular failure
0.000 0.593 0.407
E32.9 Disease of thymus, unspecified
0.000 0.593 0.407
E32.8 Other diseases of thymus
0.000 0.593 0.407
E32.1 Abscess of thymus
0.000 0.593 0.407
E32.0 Persistent hyperplasia of thymus
0.000 0.593 0.407
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.593 0.407
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.593 0.407
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.593 0.407
D59.1 Other autoimmune haemolytic anaemias
0.000 0.599 0.401
C90.0 Multiple myeloma
0.396 0.604 0.000
D83.8 Other common variable immunodeficiencies
0.000 0.606 0.393
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.606 0.393
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.606 0.393
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.606 0.393
E00-E07 Disorders of thyroid gland
0.000 0.608 0.392
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.612 0.388
E45 Retarded development following protein-energy malnutrition
0.000 0.612 0.388
E43 Unspecified severe protein-energy malnutrition
0.000 0.612 0.388
E42 Marasmic kwashiorkor
0.000 0.612 0.388
E41 Nutritional marasmus
0.000 0.612 0.388
E40 Kwashiorkor
0.000 0.612 0.388
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.613 0.386
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.613 0.386
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.613 0.386
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.613 0.386
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.613 0.386
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.613 0.386
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.613 0.386
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.613 0.386
E34.5 Androgen resistance syndrome
0.000 0.626 0.374
E34.4 Constitutional tall stature
0.000 0.626 0.374
E34.3 Short stature, not elsewhere classified
0.000 0.626 0.374
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.626 0.374
E34.1 Other hypersecretion of intestinal hormones
0.000 0.626 0.374
E27.9 Disorder of adrenal gland, unspecified
0.001 0.630 0.370
C91.5 Adult T-cell leukaemia
0.367 0.633 0.001
E28 Ovarian dysfunction
0.000 0.635 0.365
D84.8 Other specified immunodeficiencies
0.000 0.636 0.364
D84.1 Defects in the complement system
0.000 0.636 0.364
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.636 0.364
J45 Asthma
0.000 0.636 0.364
C88.0 Waldenstrom's macroglobulinaemia
0.361 0.639 0.000
C90.2 Plasmacytoma, extramedullary
0.360 0.639 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.641 0.359
E53 Deficiency of other B group vitamins
0.000 0.644 0.356
D56 Thalassaemia
0.000 0.648 0.351
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.649 0.351
E26 Hyperaldosteronism
0.001 0.651 0.348
C91.9 Lymphoid leukaemia, unspecified
0.343 0.656 0.001
Chapter II Neoplasms
0.342 0.658 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.659 0.341
E29.8 Other testicular dysfunction
0.000 0.659 0.341
E29.0 Testicular hyperfunction
0.000 0.659 0.341
E03 Other hypothyroidism
0.000 0.660 0.340
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.340 0.660 0.000
D59.8 Other acquired haemolytic anaemias
0.000 0.661 0.339
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.661 0.339
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.661 0.339
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.661 0.339
D59.3 Haemolytic-uraemic syndrome
0.000 0.661 0.339
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.661 0.339
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.661 0.339
C73 Malignant neoplasm of thyroid gland
0.338 0.662 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.664 0.336
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.665 0.335
D58 Other hereditary haemolytic anaemias
0.000 0.665 0.334
E34.8 Other specified endocrine disorders
0.000 0.667 0.332
C81.9 Hodgkin's disease, unspecified
0.329 0.671 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.671 0.329
E67 Other hyperalimentation
0.000 0.671 0.328
E68 Sequelae of hyperalimentation
0.000 0.671 0.328
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.681 0.318
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.681 0.318
D89.3 Immune reconstitution syndrome
0.000 0.681 0.318
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.681 0.318
D83.9 Common variable immunodeficiency, unspecified
0.001 0.684 0.315
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.687 0.313
E53.8 Deficiency of other specified B group vitamins
0.000 0.690 0.310
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.691 0.308
E63 Other nutritional deficiencies
0.000 0.691 0.308
E56 Other vitamin deficiencies
0.000 0.691 0.308
E50 Vitamin A deficiency
0.000 0.691 0.308
E60 Dietary zinc deficiency
0.000 0.691 0.308
E59 Dietary selenium deficiency
0.000 0.691 0.308
E54 Ascorbic acid deficiency
0.000 0.691 0.308
E52 Niacin deficiency [pellagra]
0.000 0.691 0.308
C91.8 Mature B-cell leukaemia Burkitt-type
0.307 0.691 0.001
C91.7 Other lymphoid leukaemia
0.307 0.691 0.001
C91.6 Prolymphocytic leukaemia of T-cell type
0.307 0.691 0.001
C91.3 Prolymphocytic leukaemia
0.307 0.691 0.001
C91.2 Subacute lymphocytic leukaemia
0.307 0.691 0.001
E03.9 Hypothyroidism, unspecified
0.000 0.692 0.308
E66 Obesity
0.000 0.695 0.305
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.704 0.296
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.705 0.295
D55.8 Other anaemias due to enzyme disorders
0.000 0.705 0.295
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.705 0.295
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.705 0.295
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.705 0.295
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.705 0.295
D57.8 Other sickle-cell disorders
0.000 0.705 0.295
D57.3 Sickle-cell trait
0.000 0.705 0.295
D57.2 Double heterozygous sickling disorders
0.000 0.705 0.295
D57.1 Sickle-cell anaemia without crisis
0.000 0.705 0.295
D57.0 Sickle-cell anaemia with crisis
0.000 0.705 0.295
D50.8 Other iron deficiency anaemias
0.000 0.707 0.293
C92.9 Myeloid leukaemia, unspecified
0.292 0.708 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.292 0.708 0.000
C92.7 Other myeloid leukaemia
0.292 0.708 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.292 0.708 0.000
C92.5 Acute myelomonocytic leukaemia
0.292 0.708 0.000
C92.4 Acute promyelocytic leukaemia
0.292 0.708 0.000
C92.3 Myeloid sarcoma
0.292 0.708 0.000
C92.2 Subacute myeloid leukaemia
0.292 0.708 0.000
E51 Thiamine deficiency
0.000 0.714 0.285
E58 Dietary calcium deficiency
0.000 0.716 0.284
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.719 0.281
E00 Congenital iodine-deficiency syndrome
0.000 0.719 0.281
E11 Non-insulin-dependent diabetes mellitus
0.000 0.719 0.281
E44.1 Mild protein-energy malnutrition
0.000 0.722 0.278
E44.0 Moderate protein-energy malnutrition
0.000 0.722 0.278
D89.1 Cryoglobulinaemia
0.000 0.722 0.278
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.278 0.722 0.000
C43 Malignant melanoma of skin
0.276 0.724 0.000
M06.9 Rheumatoid arthritis, unspecified
0.275 0.725 0.000
M06 Other rheumatoid arthritis
0.267 0.732 0.000
M06.0 Seronegative rheumatoid arthritis
0.266 0.734 0.000
E34.9 Endocrine disorder, unspecified
0.001 0.735 0.265
C74 Malignant neoplasm of adrenal gland
0.265 0.735 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.265 0.735 0.000
E06 Thyroiditis
0.000 0.736 0.264
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.263 0.737 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.738 0.262
E28.8 Other ovarian dysfunction
0.000 0.738 0.262
E28.1 Androgen excess
0.000 0.738 0.262
E28.0 Oestrogen excess
0.000 0.738 0.262
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.262 0.738 0.000
J45.8 Mixed asthma
0.000 0.739 0.261
J45.1 Nonallergic asthma
0.000 0.739 0.261
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.741 0.258
K50.0 Crohn's disease of small intestine
0.257 0.742 0.001
E53.1 Pyridoxine deficiency
0.000 0.745 0.255
E53.0 Riboflavin deficiency
0.000 0.745 0.255
C02 Malignant neoplasm of other and unspecified parts of tongue
0.254 0.746 0.000
D66 Hereditary factor VIII deficiency
0.000 0.747 0.253
D56.9 Thalassaemia, unspecified
0.000 0.748 0.252
D56.8 Other thalassaemias
0.000 0.748 0.252
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.748 0.252
D56.2 Delta-beta thalassaemia
0.000 0.748 0.252
D56.0 Alpha thalassaemia
0.000 0.748 0.252
D67 Hereditary factor IX deficiency
0.000 0.748 0.252
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.748 0.252
M45.X9 Ankylosing spondylitis (Site unspecified)
0.252 0.748 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.749 0.251
E26.8 Other hyperaldosteronism
0.001 0.749 0.250
E26.1 Secondary hyperaldosteronism
0.001 0.749 0.250
E11.1 With ketoacidosis
0.000 0.750 0.250
E29.1 Testicular hypofunction
0.000 0.750 0.249
E23 Hypofunction and other disorders of pituitary gland
0.001 0.750 0.248
D56.3 Thalassaemia trait
0.000 0.751 0.248
C91.0 Acute lymphoblastic leukaemia
0.246 0.753 0.001
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.246 0.754 0.000
D84.9 Immunodeficiency, unspecified
0.001 0.755 0.244
E03.5 Myxoedema coma
0.000 0.756 0.244
E03.4 Atrophy of thyroid (acquired)
0.000 0.756 0.244
E03.3 Postinfectious hypothyroidism
0.000 0.756 0.244
E03.1 Congenital hypothyroidism without goitre
0.000 0.756 0.244
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.756 0.244
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.756 0.244
C75 Malignant neoplasm of other endocrine glands and related structures
0.244 0.756 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.242 0.758 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.759 0.241
E61 Deficiency of other nutrient elements
0.000 0.759 0.240
C40-C41 Malignant neoplasms of bone and articular cartilage
0.240 0.759 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.760 0.240
D58.2 Other haemoglobinopathies
0.000 0.760 0.240
D58.1 Hereditary elliptocytosis
0.000 0.760 0.240
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.236 0.764 0.000
E67.8 Other specified hyperalimentation
0.000 0.764 0.236
E67.3 Hypervitaminosis D
0.000 0.764 0.236
E67.2 Megavitamin-B6 syndrome
0.000 0.764 0.236
E67.1 Hypercarotenaemia
0.000 0.764 0.236
E67.0 Hypervitaminosis A
0.000 0.764 0.236
D72 Other disorders of white blood cells
0.000 0.765 0.235
E66.8 Other obesity
0.000 0.766 0.234
C06 Malignant neoplasm of other and unspecified parts of mouth
0.234 0.766 0.000
C43.4 Malignant melanoma of scalp and neck
0.233 0.767 0.000
J45.0 Predominantly allergic asthma
0.000 0.768 0.232

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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