TreeWAS – Variant ID: rs1723838

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82 Fracture of lower leg, including ankle	0.000	0.979	0.021
S82.2 Fracture of shaft of tibia	0.000	0.980	0.020
S82.6 Fracture of lateral malleolus	0.000	0.981	0.019
S82.0 Fracture of patella	0.000	0.981	0.019
S82.8 Fractures of other parts of lower leg	0.000	0.982	0.018
S82.60 Fracture of lateral malleolus (closed)	0.000	0.982	0.018
S82.20 Fracture of shaft of tibia (closed)	0.000	0.982	0.018
S82.1 Fracture of upper end of tibia	0.000	0.983	0.017
S82.3 Fracture of lower end of tibia	0.000	0.983	0.017
S82.00 Fracture of patella (closed)	0.000	0.983	0.017
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.984	0.016
S82.4 Fracture of fibula alone	0.000	0.984	0.016
S80-S89 Injuries to the knee and lower leg	0.000	0.984	0.016
S82.21 Fracture of shaft of tibia (open)	0.000	0.984	0.016
S81 Open wound of lower leg	0.000	0.984	0.016
S82.9 Fracture of lower leg, part unspecified	0.000	0.984	0.015
S82.7 Multiple fractures of lower leg	0.000	0.984	0.015
S81.0 Open wound of knee	0.000	0.985	0.015
S82.10 Fracture of upper end of tibia (closed)	0.000	0.985	0.015
S82.5 Fracture of medial malleolus	0.000	0.986	0.014
S82.61 Fracture of lateral malleolus (open)	0.000	0.986	0.014
S82.30 Fracture of lower end of tibia (closed)	0.000	0.986	0.014
S81.9 Open wound of lower leg, part unspecified	0.000	0.986	0.014
S82.01 Fracture of patella (open)	0.000	0.986	0.014
H33.2 Serous retinal detachment	0.014	0.986	0.000
S82.86 Maisonneuve's fracture	0.000	0.987	0.013
S82.81 Fractures of other parts of lower leg (open)	0.000	0.987	0.013
S82.31 Fracture of lower end of tibia (open)	0.000	0.987	0.013
S82.11 Fracture of upper end of tibia (open)	0.000	0.987	0.013
I50.0 Congestive heart failure	0.000	0.987	0.013
S80 Superficial injury of lower leg	0.000	0.988	0.012
S86 Injury of muscle and tendon at lower leg level	0.000	0.988	0.012
S82.40 Fracture of fibula alone (closed)	0.000	0.988	0.012
S82.41 Fracture of fibula alone (open)	0.000	0.988	0.011
S88 Traumatic amputation of lower leg	0.000	0.988	0.011
S87 Crushing injury of lower leg	0.000	0.988	0.011
S85 Injury of blood vessels at lower leg level	0.000	0.988	0.011
S84 Injury of nerves at lower leg level	0.000	0.988	0.011
S81.7 Multiple open wounds of lower leg	0.000	0.989	0.011
S82.71 Multiple fractures of lower leg (open)	0.000	0.989	0.011
S82.70 Multiple fractures of lower leg (closed)	0.000	0.989	0.011
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.989	0.011
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.989	0.011
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.011	0.989	0.000
S82.51 Fracture of medial malleolus (open)	0.000	0.989	0.010
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.989	0.010
I69.3 Sequelae of cerebral infarction	0.010	0.990	0.000
L57.0 Actinic keratosis	0.010	0.990	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.990	0.010
H33 Retinal detachments and breaks	0.010	0.990	0.000
S80.9 Superficial injury of lower leg, unspecified	0.000	0.990	0.010
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.990	0.010
I69 Sequelae of cerebrovascular disease	0.010	0.990	0.000
S80.0 Contusion of knee	0.000	0.990	0.010
D05.9 Carcinoma in situ of breast, unspecified	0.010	0.990	0.000
S89 Other and unspecified injuries of lower leg	0.000	0.990	0.009
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.990	0.009
D05 Carcinoma in situ of breast	0.010	0.990	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.991	0.009
S80.7 Multiple superficial injuries of lower leg	0.000	0.991	0.009
D05.1 Intraductal carcinoma in situ	0.009	0.991	0.000
S86.0 Injury of Achilles tendon	0.000	0.991	0.009
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.991	0.009
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.991	0.009
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.991	0.009
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.991	0.009
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.991	0.009
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.009	0.991	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.009	0.991	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.991	0.008
S84.8 Injury of other nerves at lower leg level	0.000	0.991	0.008
S84.7 Injury of multiple nerves at lower leg level	0.000	0.991	0.008
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.991	0.008
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.991	0.008
S84.0 Injury of tibial nerve at lower leg level	0.000	0.991	0.008
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.991	0.008
S85.8 Injury of other blood vessels at lower leg level	0.000	0.991	0.008
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.991	0.008
S85.5 Injury of popliteal vein	0.000	0.991	0.008
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.991	0.008
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.991	0.008
S85.2 Injury of peroneal artery	0.000	0.991	0.008
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.991	0.008
S85.0 Injury of popliteal artery	0.000	0.991	0.008
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.991	0.008
S87.0 Crushing injury of knee	0.000	0.991	0.008
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.991	0.008
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.991	0.008
S88.0 Traumatic amputation at knee level	0.000	0.991	0.008
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.992	0.008
H33.4 Traction detachment of retina	0.008	0.992	0.000
C50.9 Breast, unspecified	0.008	0.992	0.000
H33.5 Other retinal detachments	0.008	0.992	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.992	0.008
H33.0 Retinal detachment with retinal break	0.008	0.992	0.000
C50.1 Central portion of breast	0.008	0.992	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.008	0.992	0.000
C50 Malignant neoplasm of breast	0.008	0.992	0.000
D05.0 Lobular carcinoma in situ	0.008	0.992	0.000
S83.7 Injury to multiple structures of knee	0.000	0.992	0.008
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.992	0.008
S83.3 Tear of articular cartilage of knee, current	0.000	0.992	0.008
S83.1 Dislocation of knee	0.000	0.992	0.008
S83.0 Dislocation of patella	0.000	0.992	0.008
C50.2 Upper-inner quadrant of breast	0.008	0.992	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.007	0.993	0.000
S89.8 Other specified injuries of lower leg	0.000	0.993	0.007
S89.7 Multiple injuries of lower leg	0.000	0.993	0.007
S89.1 Other specified injuries of lower leg	0.000	0.993	0.007
S89.0 Multiple injuries of lower leg	0.000	0.993	0.007
D00-D09 In situ neoplasms	0.007	0.993	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.007	0.993	0.000
D05.7 Other carcinoma in situ of breast	0.007	0.993	0.000
H33.1 Retinoschisis and retinal cysts	0.007	0.993	0.000
S80.8 Other superficial injuries of lower leg	0.000	0.993	0.007
C50.6 Axillary tail of breast	0.007	0.993	0.000
C50.3 Lower-inner quadrant of breast	0.007	0.993	0.000
D03 Melanoma in situ	0.007	0.993	0.000
H33.3 Retinal breaks without detachment	0.007	0.993	0.000
I50 Heart failure	0.000	0.993	0.007
D07 Carcinoma in situ of other and unspecified genital organs	0.007	0.993	0.000
S86.00 Unspecified injury of Achilles tendon	0.000	0.993	0.006
I50.1 Left ventricular failure	0.000	0.993	0.007
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.006	0.993	0.000
L57.5 Actinic granuloma	0.006	0.993	0.000
L57.4 Cutis laxa senilis	0.006	0.993	0.000
L57.3 Poikiloderma of Civatte	0.006	0.993	0.000
L57.2 Cutis rhomboidalis nuchae	0.006	0.993	0.000
L57.1 Actinic reticuloid	0.006	0.993	0.000
C50.5 Lower-outer quadrant of breast	0.006	0.993	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.006	0.994	0.000
D07.5 Prostate	0.006	0.994	0.000
R03.1 Nonspecific low blood-pressure reading	0.006	0.994	0.000
D04 Carcinoma in situ of skin	0.006	0.994	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.006	0.994	0.000
D03.5 Melanoma in situ of trunk	0.006	0.994	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.006	0.994	0.000
D04.4 Skin of scalp and neck	0.005	0.994	0.000
D07.1 Vulva	0.005	0.994	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.005	0.994	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.005	0.995	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.005	0.995	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.005	0.995	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.005	0.995	0.000
S89.9 Unspecified injury of lower leg	0.000	0.995	0.005
D04.5 Skin of trunk	0.005	0.995	0.000
C50.0 Nipple and areola	0.005	0.995	0.000
C50.4 Upper-outer quadrant of breast	0.005	0.995	0.000
D03.4 Melanoma in situ of scalp and neck	0.005	0.995	0.000
D03.9 Melanoma in situ, unspecified	0.005	0.995	0.000
D03.8 Melanoma in situ of other sites	0.005	0.995	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.005	0.995	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.005	0.995	0.000
D03.0 Melanoma in situ of lip	0.005	0.995	0.000
D07.6 Other and unspecified male genital organs	0.005	0.995	0.000
D07.4 Penis	0.005	0.995	0.000
D07.3 Other and unspecified female genital organs	0.005	0.995	0.000
D07.2 Vagina	0.005	0.995	0.000
D07.0 Endometrium	0.005	0.995	0.000
S83.2 Tear of meniscus, current	0.000	0.995	0.005
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.995	0.005
H34 Retinal vascular occlusions	0.005	0.995	0.000
O73.0 Retained placenta, without haemorrhage	0.005	0.995	0.000
D04.3 Skin of other and unspecified parts of face	0.005	0.995	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.005	0.995	0.000
H30-H36 Disorders of choroid and retina	0.005	0.995	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.005	0.995	0.000
H34.2 Other retinal artery occlusions	0.005	0.995	0.000
D04.9 Skin, unspecified	0.005	0.995	0.000
D04.8 Skin of other sites	0.005	0.995	0.000
D04.2 Skin of ear and external auricular canal	0.005	0.995	0.000
D04.1 Skin of eyelid, including canthus	0.005	0.995	0.000
D04.0 Skin of lip	0.005	0.995	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.005	0.995	0.000
D09 Carcinoma in situ of other and unspecified sites	0.005	0.995	0.000
I65.2 Occlusion and stenosis of carotid artery	0.005	0.995	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.005	0.995	0.000
D04.7 Skin of lower limb, including hip	0.004	0.995	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.995	0.005
H34.8 Other retinal vascular occlusions	0.005	0.995	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.004	0.995	0.000
I60-I69 Cerebrovascular diseases	0.004	0.996	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.004	0.996	0.000
Z35.5 Supervision of elderly primigravida	0.004	0.996	0.000
I62 Other nontraumatic intracranial haemorrhage	0.004	0.996	0.000
L40.9 Psoriasis, unspecified	0.000	0.996	0.004
D00.2 Stomach	0.004	0.996	0.000
D00.1 Oesophagus	0.004	0.996	0.000
D00.0 Lip, oral cavity and pharynx	0.004	0.996	0.000
D01.9 Digestive organ, unspecified	0.004	0.996	0.000
D01.7 Other specified digestive organs	0.004	0.996	0.000
D01.5 Liver, gallbladder and bile ducts	0.004	0.996	0.000
D01.4 Other and unspecified parts of intestine	0.004	0.996	0.000
D01.3 Anus and anal canal	0.004	0.996	0.000
D01.2 Rectum	0.004	0.996	0.000
D01.1 Rectosigmoid junction	0.004	0.996	0.000
D01.0 Colon	0.004	0.996	0.000
D02.4 Respiratory system, unspecified	0.004	0.996	0.000
D02.3 Other parts of respiratory system	0.004	0.996	0.000
D02.2 Bronchus and lung	0.004	0.996	0.000
D02.1 Trachea	0.004	0.996	0.000
D02.0 Larynx	0.004	0.996	0.000
D06 Carcinoma in situ of cervix uteri	0.004	0.996	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.004	0.996	0.000
H34.9 Retinal vascular occlusion, unspecified	0.004	0.996	0.000
H34.1 Central retinal artery occlusion	0.004	0.996	0.000
H34.0 Transient retinal artery occlusion	0.004	0.996	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.996	0.004
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.004	0.996	0.000
M47.82 Other spondylosis (Cervical region)	0.000	0.996	0.004
H32 Chorioretinal disorders in diseases classified elsewhere	0.004	0.996	0.000
H31 Other disorders of choroid	0.004	0.996	0.000
H30 Chorioretinal inflammation	0.004	0.996	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.004	0.996	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.004	0.996	0.000
D09.9 Carcinoma in situ, unspecified	0.003	0.996	0.000
D09.7 Carcinoma in situ of other specified sites	0.003	0.996	0.000
D09.3 Thyroid and other endocrine glands	0.003	0.996	0.000
D09.2 Eye	0.003	0.996	0.000
D09.1 Other and unspecified urinary organs	0.003	0.996	0.000
D04.6 Skin of upper limb, including shoulder	0.003	0.996	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.003	0.996	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.003	0.996	0.000
Z35 Supervision of high-risk pregnancy	0.004	0.996	0.000
C50-C50 Malignant neoplasm of breast	0.003	0.996	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.003	0.996	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.003	0.996	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.003	0.996	0.000
I65.1 Occlusion and stenosis of basilar artery	0.003	0.996	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.003	0.996	0.000
H43.8 Other disorders of vitreous body	0.000	0.997	0.003
I68 Cerebrovascular disorders in diseases classified elsewhere	0.003	0.997	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.003	0.997	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.003	0.997	0.000
H43.1 Vitreous haemorrhage	0.000	0.997	0.003
I50.9 Heart failure, unspecified	0.000	0.997	0.003
D69.6 Thrombocytopenia, unspecified	0.000	0.997	0.003
I62.1 Nontraumatic extradural haemorrhage	0.003	0.997	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.997	0.003
Z99.2 Dependence on renal dialysis	0.003	0.997	0.000
I61 Intracerebral haemorrhage	0.003	0.997	0.000
Z35.8 Supervision of other high-risk pregnancies	0.003	0.997	0.000
D06.7 Other parts of cervix	0.003	0.997	0.000
D06.1 Exocervix	0.003	0.997	0.000
D06.0 Endocervix	0.003	0.997	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.003	0.997	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.003	0.997	0.000
I45.1 Other and unspecified right bundle-branch block	0.003	0.997	0.000
H43 Disorders of vitreous body	0.000	0.997	0.003
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.003	0.997	0.000
L58 Radiodermatitis	0.003	0.997	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.003	0.997	0.000
L55 Sunburn	0.003	0.997	0.000
H18 Other disorders of cornea	0.003	0.997	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.003	0.997	0.000
O73 Retained placenta and membranes, without haemorrhage	0.003	0.997	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.003	0.997	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
H30.9 Chorioretinal inflammation, unspecified	0.003	0.997	0.000
H30.8 Other chorioretinal inflammations	0.003	0.997	0.000
H30.2 Posterior cyclitis	0.003	0.997	0.000
H30.1 Disseminated chorioretinal inflammation	0.003	0.997	0.000
H30.0 Focal chorioretinal inflammation	0.003	0.997	0.000
H31.9 Disorder of choroid, unspecified	0.003	0.997	0.000
H31.8 Other specified disorders of choroid	0.003	0.997	0.000
H31.4 Choroidal detachment	0.003	0.997	0.000
H31.3 Choroidal haemorrhage and rupture	0.003	0.997	0.000
H31.2 Hereditary choroidal dystrophy	0.003	0.997	0.000
H31.1 Choroidal degeneration	0.003	0.997	0.000
H31.0 Chorioretinal scars	0.003	0.997	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.003	0.997	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.003	0.997	0.000
D09.0 Bladder	0.003	0.997	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.997	0.003
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.003	0.997	0.000
M06.9 Rheumatoid arthritis, unspecified	0.003	0.997	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.003	0.997	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.003	0.997	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.003	0.997	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.003	0.997	0.000
Z35.6 Supervision of very young primigravida	0.003	0.997	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.003	0.997	0.000
G25.0 Essential tremor	0.003	0.997	0.000
C50.8 Overlapping lesion of breast	0.002	0.997	0.001
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.003	0.997	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.003	0.997	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.003	0.997	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.003	0.997	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.003	0.997	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.003	0.997	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.003	0.997	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.003	0.997	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.003	0.997	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
I68.0 Cerebral amyloid angiopathy	0.003	0.997	0.000
H36 Retinal disorders in diseases classified elsewhere	0.003	0.997	0.000
H18.9 Disorder of cornea, unspecified	0.003	0.997	0.000
H18.4 Corneal degeneration	0.003	0.997	0.000
H18.6 Keratoconus	0.003	0.997	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.997	0.003
E80.4 Gilbert's syndrome	0.000	0.997	0.003
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.003	0.997	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.002	0.997	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.002	0.997	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.002	0.997	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.002	0.997	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.002	0.997	0.000
O02.1 Missed abortion	0.003	0.997	0.000
H18.2 Other corneal oedema	0.003	0.997	0.000
H21 Other disorders of iris and ciliary body	0.003	0.997	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.003	0.997	0.000
I61.8 Other intracerebral haemorrhage	0.002	0.997	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.002	0.997	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.003	0.997	0.000
N03.9 Unspecified	0.000	0.997	0.003
M06.98 Rheumatoid arthritis, unspecified (Other)	0.002	0.997	0.000
Z99.1 Dependence on respirator	0.002	0.997	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.002	0.997	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.002	0.998	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.002	0.998	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.002	0.998	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
H43.9 Disorder of vitreous body, unspecified	0.000	0.998	0.002
H43.2 Crystalline deposits in vitreous body	0.000	0.998	0.002
H43.0 Vitreous prolapse	0.000	0.998	0.002
L55.9 Sunburn, unspecified	0.002	0.998	0.000
L55.8 Other sunburn	0.002	0.998	0.000
L55.2 Sunburn of third degree	0.002	0.998	0.000
L55.1 Sunburn of second degree	0.002	0.998	0.000
L55.0 Sunburn of first degree	0.002	0.998	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.002	0.998	0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.002	0.998	0.000
L56.4 Polymorphous light eruption	0.002	0.998	0.000
L56.3 Solar urticaria	0.002	0.998	0.000
L56.2 Photocontact dermatitis [berloque dermatitis]	0.002	0.998	0.000
L56.1 Drug photoallergic response	0.002	0.998	0.000
L56.0 Drug phototoxic response	0.002	0.998	0.000
L58.9 Radiodermatitis, unspecified	0.002	0.998	0.000
L58.1 Chronic radiodermatitis	0.002	0.998	0.000
L58.0 Acute radiodermatitis	0.002	0.998	0.000
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified	0.002	0.998	0.000
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation	0.002	0.998	0.000
L59.0 Erythema ab igne [dermatitis ab igne]	0.002	0.998	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
H18.7 Other corneal deformities	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.002	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H02.5 Other disorders affecting eyelid function	0.000	0.998	0.002
D68.8 Other specified coagulation defects	0.002	0.998	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.002	0.998	0.000
O02 Other abnormal products of conception	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.002	0.998	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.002	0.998	0.000
H20 Iridocyclitis	0.002	0.998	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.002	0.998	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.002	0.998	0.000
D69.5 Secondary thrombocytopenia	0.000	0.998	0.002
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
H43.3 Other vitreous opacities	0.000	0.998	0.002
T80.2 Infections following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.002	0.998	0.000
H35 Other retinal disorders	0.002	0.998	0.000
L40 Psoriasis	0.000	0.998	0.002
D69.9 Haemorrhagic condition, unspecified	0.000	0.998	0.002
D69.8 Other specified haemorrhagic conditions	0.000	0.998	0.002
D69.4 Other primary thrombocytopenia	0.000	0.998	0.002
D69.2 Other nonthrombocytopenic purpura	0.000	0.998	0.002
D69.1 Qualitative platelet defects	0.000	0.998	0.002
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
O20.0 Threatened abortion	0.002	0.998	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
L05.9 Pilonidal cyst without abscess	0.002	0.998	0.000
O21.8 Other vomiting complicating pregnancy	0.002	0.998	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
H15 Disorders of sclera	0.002	0.998	0.000
D69.0 Allergic purpura	0.000	0.998	0.002
H21.9 Disorder of iris and ciliary body, unspecified	0.002	0.998	0.000
H21.4 Pupillary membranes	0.002	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.998	0.000
H21.2 Degeneration of iris and ciliary body	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.998	0.000
M23.8 Other internal derangements of knee	0.000	0.998	0.002
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
I60 Subarachnoid haemorrhage	0.002	0.998	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.002	0.998	0.000
G25 Other extrapyramidal and movement disorders	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.002	0.998	0.000
H17 Corneal scars and opacities	0.002	0.998	0.000
R61.9 Hyperhidrosis, unspecified	0.002	0.998	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T80.6 Other serum reactions	0.002	0.998	0.000
T80.5 Anaphylactic shock due to serum	0.002	0.998	0.000
T80.4 Rh incompatibility reaction	0.002	0.998	0.000
T80.3 ABO incompatibility reaction	0.002	0.998	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
D68 Other coagulation defects	0.002	0.998	0.000
O21 Excessive vomiting in pregnancy	0.002	0.998	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.002	0.998	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.002	0.998	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.002	0.998	0.000
T82.3 Mechanical complication of other vascular grafts	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
H35.9 Retinal disorder, unspecified	0.002	0.998	0.000
O14.0 Moderate preeclampsia	0.002	0.998	0.000
I24 Other acute ischaemic heart diseases	0.000	0.998	0.002
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
K51.9 Ulcerative colitis, unspecified	0.002	0.998	0.000
O02.9 Abnormal product of conception, unspecified	0.002	0.998	0.000
O02.8 Other specified abnormal products of conception	0.002	0.998	0.000
O21.2 Late vomiting of pregnancy	0.002	0.998	0.000
Z74.0 Reduced mobility	0.000	0.998	0.002
H35.0 Background retinopathy and retinal vascular changes	0.002	0.998	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.002	0.998	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
H20.2 Lens-induced iridocyclitis	0.002	0.998	0.000
H20.1 Chronic iridocyclitis	0.002	0.998	0.000
T86.1 Kidney transplant failure and rejection	0.002	0.998	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.002	0.998	0.000
L40.0 Psoriasis vulgaris	0.000	0.998	0.002
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.002	0.998	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.002	0.998	0.000
Z99.4 Dependence on artificial heart	0.002	0.998	0.000
Z99.0 Dependence on aspirator	0.002	0.998	0.000
D68.9 Coagulation defect, unspecified	0.002	0.998	0.000
H35.1 Retinopathy of prematurity	0.002	0.998	0.000
L40.8 Other psoriasis	0.000	0.998	0.002
L40.4 Guttate psoriasis	0.000	0.998	0.002
L40.3 Pustulosis palmaris et plantaris	0.000	0.998	0.002
L40.2 Acrodermatitis continua	0.000	0.998	0.002
L40.1 Generalised pustular psoriasis	0.000	0.998	0.002
T85.2 Mechanical complication of intraocular lens	0.002	0.998	0.000
D06.9 Cervix, unspecified	0.001	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.002	0.998	0.000
R74.8 Abnormal levels of other serum enzymes	0.000	0.998	0.002
T86 Failure and rejection of transplanted organs and tissues	0.002	0.998	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.002
E61.1 Iron deficiency	0.000	0.998	0.002
H02.4 Ptosis of eyelid	0.000	0.998	0.002
H20.9 Iridocyclitis, unspecified	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.002	0.998	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.002	0.998	0.000
T87 Complications peculiar to reattachment and amputation	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
H15.9 Disorder of sclera, unspecified	0.002	0.998	0.000
H15.8 Other disorders of sclera	0.002	0.998	0.000
H15.1 Episcleritis	0.002	0.998	0.000
H15.0 Scleritis	0.002	0.998	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.002	0.998	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.001	0.998	0.000
Z99.8 Dependence on other enabling machines and devices	0.002	0.998	0.000
H16.8 Other keratitis	0.002	0.998	0.000
H16.4 Corneal neovascularisation	0.002	0.998	0.000
H16.3 Interstitial and deep keratitis	0.002	0.998	0.000
H16.2 Keratoconjunctivitis	0.002	0.998	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.998	0.000
H16.0 Corneal ulcer	0.002	0.998	0.000
Z99.3 Dependence on wheelchair	0.002	0.998	0.000
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.998	0.002
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.998	0.002
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.998	0.002
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.998	0.002
E53.8 Deficiency of other specified B group vitamins	0.000	0.998	0.002
G23.8 Other specified degenerative diseases of basal ganglia	0.002	0.998	0.000
H16.9 Keratitis, unspecified	0.002	0.998	0.000
I60.8 Other subarachnoid haemorrhage	0.001	0.998	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.001	0.998	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.001	0.998	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.001	0.998	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.001	0.998	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.001	0.998	0.000
O81.4 Vacuum extractor delivery	0.002	0.998	0.000
D73.0 Hyposplenism	0.000	0.998	0.002
H35.5 Hereditary retinal dystrophy	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations