TreeWAS – Variant ID: rs1727307

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M17.9 Gonarthrosis, unspecified	0.941	0.059	0.000
M17 Gonarthrosis [arthrosis of knee]	0.573	0.427	0.000
M17.0 Primary gonarthrosis, bilateral	0.546	0.454	0.000
M17.1 Other primary gonarthrosis	0.445	0.555	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.382	0.617	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.376	0.624	0.000
M17.3 Other posttraumatic gonarthrosis	0.330	0.669	0.000
M17.5 Other secondary gonarthrosis	0.294	0.706	0.000
M15-M19 Arthrosis	0.047	0.953	0.000
M15 Polyarthrosis	0.037	0.963	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.033	0.967	0.000
M19 Other arthrosis	0.032	0.968	0.000
M19.0 Primary arthrosis of other joints	0.032	0.968	0.000
M15.4 Erosive (osteo)arthrosis	0.030	0.970	0.000
M15.8 Other polyarthrosis	0.030	0.970	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.029	0.971	0.000
M15.1 Heberden's nodes (with arthropathy)	0.028	0.972	0.000
M15.0 Primary generalised (osteo)arthrosis	0.028	0.972	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.027	0.973	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.027	0.973	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.026	0.974	0.000
M15.9 Polyarthrosis, unspecified	0.026	0.974	0.000
M19.8 Other specified arthrosis	0.025	0.975	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.023	0.977	0.000
L03.2 Cellulitis of face	0.000	0.977	0.023
M19.03 Primary arthrosis of other joints (Forearm)	0.023	0.977	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.022	0.978	0.000
M19.08 Primary arthrosis of other joints (Other)	0.022	0.978	0.000
M19.2 Other secondary arthrosis	0.022	0.978	0.000
M15.3 Secondary multiple arthrosis	0.021	0.978	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.021	0.979	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.021	0.979	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.020	0.980	0.000
M19.84 Other specified arthrosis (Hand)	0.019	0.980	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.019	0.981	0.000
M19.88 Other specified arthrosis (Other)	0.018	0.982	0.000
M19.86 Other specified arthrosis (Lower leg)	0.018	0.982	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.018	0.982	0.000
M19.83 Other specified arthrosis (Forearm)	0.018	0.982	0.000
M19.82 Other specified arthrosis (Upper arm)	0.018	0.982	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.018	0.982	0.000
M15.99 Polyosteoarthritis, unspecified	0.017	0.983	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.016	0.984	0.000
M19.28 Other secondary arthrosis (Other)	0.016	0.984	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.016	0.984	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.016	0.984	0.000
M19.24 Other secondary arthrosis (Hand)	0.016	0.984	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.016	0.984	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.016	0.984	0.000
M19.89 Other specified arthrosis (Site unspecified)	0.015	0.984	0.000
M19.23 Other secondary arthrosis (Forearm)	0.015	0.985	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.015	0.985	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.015	0.985	0.000
C44.6 Skin of upper limb, including shoulder	0.014	0.986	0.000
K90.0 Coeliac disease	0.013	0.987	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.987	0.013
M18 Arthrosis of first carpometacarpal joint	0.011	0.988	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.011	0.989	0.000
M19.1 Posttraumatic arthrosis of other joints	0.008	0.990	0.001
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.009	0.991	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.008	0.991	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.008	0.991	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.008	0.991	0.000
I63.9 Cerebral infarction, unspecified	0.008	0.992	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.008	0.992	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.007	0.992	0.001
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.006	0.993	0.001
M19.18 Post-traumatic arthrosis of other joints (Other)	0.006	0.993	0.001
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.006	0.993	0.001
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.006	0.993	0.001
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.006	0.993	0.001
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.993	0.007
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.006	0.993	0.001
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.005	0.994	0.001
M23.30 Other meniscus derangements (Multiple sites)	0.006	0.994	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.005	0.994	0.001
R09.0 Asphyxia	0.000	0.994	0.006
V18.0 Driver injured in nontraffic accident	0.000	0.995	0.005
A46 Erysipelas	0.000	0.995	0.005
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.995	0.005
K90 Intestinal malabsorption	0.005	0.995	0.000
D13.2 Duodenum	0.005	0.995	0.000
I05.0 Mitral stenosis	0.000	0.995	0.005
C67.2 Lateral wall of bladder	0.005	0.995	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.004	0.996	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.996	0.004
R09.2 Respiratory arrest	0.000	0.996	0.004
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.004	0.996	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.004	0.996	0.000
C67.5 Bladder neck	0.004	0.996	0.000
R09.3 Abnormal sputum	0.000	0.996	0.004
V18 Pedal cyclist injured in noncollision transport accident	0.000	0.996	0.004
D03.7 Melanoma in situ of lower limb, including hip	0.004	0.996	0.000
L29.9 Pruritus, unspecified	0.004	0.996	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.001	0.996	0.002
C67 Malignant neoplasm of bladder	0.004	0.996	0.000
K90.3 Pancreatic steatorrhoea	0.004	0.996	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.004	0.996	0.000
K90.1 Tropical sprue	0.004	0.996	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
M20.3 Other deformity of hallux (acquired)	0.004	0.996	0.000
N60.8 Other benign mammary dysplasias	0.000	0.996	0.004
C67.0 Trigone of bladder	0.004	0.996	0.000
C50.1 Central portion of breast	0.000	0.996	0.004
M19.98 Arthrosis, unspecified (Other)	0.004	0.996	0.000
D03 Melanoma in situ	0.004	0.996	0.000
I05 Rheumatic mitral valve diseases	0.000	0.997	0.003
C67.1 Dome of bladder	0.003	0.997	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.003	0.997	0.000
K90.8 Other intestinal malabsorption	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
K83.0 Cholangitis	0.000	0.997	0.003
C67.8 Overlapping lesion of bladder	0.003	0.997	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.003	0.997	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.997	0.003
V18.3 Person injured while boarding or alighting	0.000	0.997	0.003
A49 Bacterial infection of unspecified site	0.000	0.997	0.003
D03.5 Melanoma in situ of trunk	0.003	0.997	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.000	0.997	0.003
V18.4 Driver injured in traffic accident	0.000	0.997	0.003
D03.1 Melanoma in situ of eyelid, including canthus	0.003	0.997	0.000
A30-A49 Other bacterial diseases	0.000	0.997	0.003
C67.4 Posterior wall of bladder	0.003	0.997	0.000
A39.0 Meningococcal meningitis	0.000	0.997	0.003
A40.8 Other streptococcal septicaemia	0.000	0.997	0.003
A49.9 Bacterial infection, unspecified	0.000	0.997	0.003
C67.7 Urachus	0.003	0.997	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.997	0.003
K90.9 Intestinal malabsorption, unspecified	0.003	0.997	0.000
V18.5 Passenger injured in traffic accident	0.000	0.997	0.003
H66.3 Other chronic suppurative otitis media	0.003	0.997	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
A39 Meningococcal infection	0.000	0.997	0.003
D03.8 Melanoma in situ of other sites	0.003	0.997	0.000
M23.3 Other meniscus derangements	0.003	0.997	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.000	0.997	0.003
A49.0 Staphylococcal infection, unspecified	0.000	0.997	0.003
V18.1 Passenger injured in nontraffic accident	0.000	0.997	0.003
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.997	0.003
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
A40 Streptococcal septicaemia	0.000	0.997	0.003
G35 Multiple sclerosis	0.000	0.997	0.003
D03.9 Melanoma in situ, unspecified	0.003	0.997	0.000
D03.0 Melanoma in situ of lip	0.003	0.997	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.003	0.997	0.000
L65.9 Nonscarring hair loss, unspecified	0.000	0.997	0.003
C67.3 Anterior wall of bladder	0.003	0.997	0.000
A49.8 Other bacterial infections of unspecified site	0.000	0.997	0.003
T82.1 Mechanical complication of cardiac electronic device	0.000	0.997	0.003
D25.9 Leiomyoma of uterus, unspecified	0.003	0.997	0.000
A49.3 Mycoplasma infection, unspecified	0.000	0.997	0.002
E27.2 Addisonian crisis	0.003	0.997	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.997	0.003
I05.8 Other mitral valve diseases	0.000	0.997	0.002
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.000	0.997	0.002
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.000	0.997	0.002
C67.6 Ureteric orifice	0.002	0.997	0.000
A44 Bartonellosis	0.000	0.997	0.002
A43 Nocardiosis	0.000	0.997	0.002
A37 Whooping cough	0.000	0.997	0.002
A36 Diphtheria	0.000	0.997	0.002
A32 Listeriosis	0.000	0.997	0.002
A30 Leprosy [Hansen's disease]	0.000	0.997	0.002
A38 Scarlet fever	0.000	0.997	0.002
A35 Other tetanus	0.000	0.997	0.002
A34 Obstetrical tetanus	0.000	0.997	0.002
A33 Tetanus neonatorum	0.000	0.997	0.002
N60.3 Fibrosclerosis of breast	0.000	0.997	0.003
A42 Actinomycosis	0.000	0.997	0.002
D03.4 Melanoma in situ of scalp and neck	0.002	0.998	0.000
A39.9 Meningococcal infection, unspecified	0.000	0.998	0.002
A39.8 Other meningococcal infections	0.000	0.998	0.002
A39.5 Meningococcal heart disease	0.000	0.998	0.002
A39.3 Chronic meningococcaemia	0.000	0.998	0.002
A39.2 Acute meningococcaemia	0.000	0.998	0.002
A39.1 Waterhouse-Friderichsen syndrome	0.000	0.998	0.002
M23.37 Other meniscus derangements-Capsular lig	0.002	0.998	0.000
N60.4 Mammary duct ectasia	0.000	0.998	0.002
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
A31 Infection due to other mycobacteria	0.000	0.998	0.002
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.002	0.998	0.000
A40.0 Septicaemia due to streptococcus, group A	0.000	0.998	0.002
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.998	0.002
C50.3 Lower-inner quadrant of breast	0.000	0.998	0.002
N60 Benign mammary dysplasia	0.000	0.998	0.002
A40.2 Septicaemia due to streptococcus, group D	0.000	0.998	0.002
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.998	0.002
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.002
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.000	0.998	0.002
A48 Other bacterial diseases, not elsewhere classified	0.000	0.998	0.002
A40.9 Streptococcal septicaemia, unspecified	0.000	0.998	0.002
L72.0 Epidermal cyst	0.002	0.998	0.000
N60.9 Benign mammary dysplasia, unspecified	0.000	0.998	0.002
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
S50.0 Contusion of elbow	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
A39.4 Meningococcaemia, unspecified	0.000	0.998	0.002
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.998	0.002
A30.9 Leprosy, unspecified	0.000	0.998	0.002
A30.8 Other forms of leprosy	0.000	0.998	0.002
A30.5 Lepromatous leprosy	0.000	0.998	0.002
A30.4 Borderline lepromatous leprosy	0.000	0.998	0.002
A30.3 Borderline leprosy	0.000	0.998	0.002
A30.2 Borderline tuberculoid leprosy	0.000	0.998	0.002
A30.1 Tuberculoid leprosy	0.000	0.998	0.002
A30.0 Indeterminate leprosy	0.000	0.998	0.002
A32.9 Listeriosis, unspecified	0.000	0.998	0.002
A32.8 Other forms of listeriosis	0.000	0.998	0.002
A32.7 Listerial septicaemia	0.000	0.998	0.002
A32.1 Listerial meningitis and meningoencephalitis	0.000	0.998	0.002
A32.0 Cutaneous listeriosis	0.000	0.998	0.002
A36.9 Diphtheria, unspecified	0.000	0.998	0.002
A36.8 Other diphtheria	0.000	0.998	0.002
A36.3 Cutaneous diphtheria	0.000	0.998	0.002
A36.2 Laryngeal diphtheria	0.000	0.998	0.002
A36.1 Nasopharyngeal diphtheria	0.000	0.998	0.002
A36.0 Pharyngeal diphtheria	0.000	0.998	0.002
A37.9 Whooping cough, unspecified	0.000	0.998	0.002
A37.8 Whooping cough due to other Bordetella species	0.000	0.998	0.002
A37.1 Whooping cough due to Bordetella parapertussis	0.000	0.998	0.002
A37.0 Whooping cough due to Bordetella pertussis	0.000	0.998	0.002
A43.9 Nocardiosis, unspecified	0.000	0.998	0.002
A43.8 Other forms of nocardiosis	0.000	0.998	0.002
A43.1 Cutaneous nocardiosis	0.000	0.998	0.002
A43.0 Pulmonary nocardiosis	0.000	0.998	0.002
A44.9 Bartonellosis, unspecified	0.000	0.998	0.002
A44.8 Other forms of bartonellosis	0.000	0.998	0.002
A44.1 Cutaneous and mucocutaneous bartonellosis	0.000	0.998	0.002
A44.0 Systemic bartonellosis	0.000	0.998	0.002
I08.0 Disorders of both mitral and aortic valves	0.000	0.998	0.002
L81.4 Other melanin hyperpigmentation	0.000	0.998	0.002
M19.9 Arthrosis, unspecified	0.002	0.998	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.002	0.998	0.000
A42.9 Actinomycosis, unspecified	0.000	0.998	0.002
A42.7 Actinomycotic septicaemia	0.000	0.998	0.002
A42.2 Cervicofacial actinomycosis	0.000	0.998	0.002
A42.1 Abdominal actinomycosis	0.000	0.998	0.002
A42.0 Pulmonary actinomycosis	0.000	0.998	0.002
M67.8 Other specified disorders of synovium and tendon	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
R15 Faecal incontinence	0.000	0.998	0.002
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.002	0.998	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.998	0.002
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
A40.1 Septicaemia due to streptococcus, group B	0.000	0.998	0.002
I08 Multiple valve diseases	0.000	0.998	0.002
A31.1 Cutaneous mycobacterial infection	0.000	0.998	0.002
A42.8 Other forms of actinomycosis	0.000	0.998	0.002
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.002	0.998	0.000
I63 Cerebral infarction	0.002	0.998	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.998	0.002
S81.9 Open wound of lower leg, part unspecified	0.000	0.998	0.002
A31.8 Other mycobacterial infections	0.000	0.998	0.002
A31.0 Pulmonary mycobacterial infection	0.000	0.998	0.002
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.998	0.002
A31.9 Mycobacterial infection, unspecified	0.000	0.998	0.002
E16.1 Other hypoglycaemia	0.002	0.998	0.000
N60.2 Fibroadenosis of breast	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
A48.8 Other specified bacterial diseases	0.000	0.998	0.002
A48.4 Brazilian purpuric fever	0.000	0.998	0.002
A48.2 Nonpneumonic Legionnaires' disease [Pontiac fever]	0.000	0.998	0.002
A48.0 Gas gangrene	0.000	0.998	0.002
A49.1 Streptococcal infection, unspecified	0.000	0.998	0.002
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.998	0.002
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
M54.16 Radiculopathy (Lumbar region)	0.002	0.998	0.000
A48.3 Toxic shock syndrome	0.000	0.998	0.002
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.000	0.998	0.002
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
R21 Rash and other nonspecific skin eruption	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
I71 Aortic aneurysm and dissection	0.000	0.998	0.002
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
I09 Other rheumatic heart diseases	0.000	0.998	0.002
Q66 Congenital deformities of feet	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.000	0.998	0.002
Q66.7 Pes cavus	0.002	0.998	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.002	0.998	0.000
M85.68 Other cyst of bone (Other)	0.000	0.998	0.002
I08.8 Other multiple valve diseases	0.000	0.998	0.002
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.002	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.998	0.002
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
I06 Rheumatic aortic valve diseases	0.000	0.998	0.002
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.002	0.998	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.002	0.998	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.998	0.002
I15.1 Hypertension secondary to other renal disorders	0.002	0.998	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.998	0.002
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
N85.0 Endometrial glandular hyperplasia	0.002	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.002	0.998	0.000
A48.1 Legionnaires' disease	0.000	0.998	0.001
E16.0 Drug-induced hypoglycaemia without coma	0.002	0.998	0.000
I49.8 Other specified cardiac arrhythmias	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
T44.0 Anticholinesterase agents	0.001	0.998	0.000
T36.3 Macrolides	0.001	0.998	0.000
T81.9 Unspecified complication of procedure	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.002	0.998	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
I09.9 Rheumatic heart disease, unspecified	0.000	0.998	0.001
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.998	0.000
Q66.2 Metatarsus varus	0.001	0.998	0.000
T36.4 Tetracyclines	0.001	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.998	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.002	0.998	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.998	0.001
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.998	0.001
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.998	0.001
T37.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.001	0.998	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.998	0.001
I09.8 Other specified rheumatic heart diseases	0.000	0.998	0.001
I09.2 Chronic rheumatic pericarditis	0.000	0.998	0.001
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.998	0.001
I09.0 Rheumatic myocarditis	0.000	0.998	0.001
Q66.5 Congenital pes planus	0.001	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.998	0.000
Q66.1 Talipes calcaneovarus	0.001	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.001	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.001	0.998	0.000
T36.6 Rifamycins	0.001	0.998	0.000
T36.5 Aminoglycosides	0.001	0.998	0.000
T36.2 Chloramphenicol group	0.001	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.000	0.998	0.001
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.998	0.001
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.998	0.000
D25.2 Subserosal leiomyoma of uterus	0.002	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.001
I06.8 Other rheumatic aortic valve diseases	0.000	0.998	0.001
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.998	0.001
H73.8 Other specified disorders of tympanic membrane	0.001	0.999	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.001	0.999	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.999	0.001
I50.1 Left ventricular failure	0.000	0.999	0.001
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.999	0.001
S90.3 Contusion of other and unspecified parts of foot	0.000	0.999	0.001
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.001	0.999	0.000
E27.1 Primary adrenocortical insufficiency	0.001	0.999	0.000
K11.7 Disturbances of salivary secretion	0.000	0.999	0.001
T48.5 Anti-common-cold drugs	0.001	0.999	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.001	0.999	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.001	0.999	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.001	0.999	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.001	0.999	0.000
E16.4 Abnormal secretion of gastrin	0.001	0.999	0.000
E16.3 Increased secretion of glucagon	0.001	0.999	0.000
L81.8 Other specified disorders of pigmentation	0.000	0.999	0.001
N49.2 Inflammatory disorders of scrotum	0.000	0.999	0.001
X47.0 Home	0.000	0.999	0.001
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.001	0.999	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.999	0.001
I06.1 Rheumatic aortic insufficiency	0.000	0.999	0.001
N90.7 Vulvar cyst	0.000	0.999	0.001
T36.8 Other systemic antibiotics	0.001	0.999	0.000
T49.9 Topical agent, unspecified	0.001	0.999	0.000
T49.8 Other topical agents	0.001	0.999	0.000
T49.7 Dental drugs, topically applied	0.001	0.999	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.001	0.999	0.000
T49.5 Ophthalmological drugs and preparations	0.001	0.999	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.999	0.000
T49.3 Emollients, demulcents and protectants	0.001	0.999	0.000
T49.2 Local astringents and local detergents	0.001	0.999	0.000
T49.1 Antipruritics	0.001	0.999	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.999	0.001
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.999	0.001
M85.8 Other specified disorders of bone density and structure	0.000	0.999	0.001
Q66.0 Talipes equinovarus	0.001	0.999	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.001	0.999	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.001	0.999	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.999	0.001
A41.4 Septicaemia due to anaerobes	0.000	0.999	0.001
L81.9 Disorder of pigmentation, unspecified	0.000	0.999	0.001
S06.8 Other intracranial injuries	0.000	0.999	0.001
S70.1 Contusion of thigh	0.001	0.999	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.999	0.000
T37.5 Antiviral drugs	0.001	0.999	0.000
T37.4 Anthelminthics	0.001	0.999	0.000
T37.3 Other antiprotozoal drugs	0.001	0.999	0.000
T37.1 Antimycobacterial drugs	0.001	0.999	0.000
T37.0 Sulphonamides	0.001	0.999	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.999	0.000
T48.4 Expectorants	0.001	0.999	0.000
T48.3 Antitussives	0.001	0.999	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.999	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
T48.0 Oxytocic drugs	0.001	0.999	0.000
A41 Other septicaemia	0.000	0.999	0.001
T47.4 Other laxatives	0.001	0.999	0.000
T47.2 Stimulant laxatives	0.001	0.999	0.000
L81 Other disorders of pigmentation	0.000	0.999	0.001
C44.0 Skin of lip	0.001	0.999	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.001	0.999	0.000
M85.6 Other cyst of bone	0.000	0.999	0.001
T47.0 Histamine H(2)-receptor antagonists	0.001	0.999	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.999	0.001
G47.1 Disorders of excessive somnolence [hypersomnias]	0.001	0.999	0.000
K07.6 Temporomandibular joint disorders	0.001	0.999	0.000
T38.0 Glucocorticoids and synthetic analogues	0.001	0.999	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.001	0.999	0.000
S82.40 Fracture of fibula alone (closed)	0.001	0.999	0.000
E28.3 Primary ovarian failure	0.000	0.999	0.001
T37.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.999	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.999	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.999	0.000
T47.7 Emetics	0.001	0.999	0.000
T47.6 Antidiarrhoeal drugs	0.001	0.999	0.000
T47.5 Digestants	0.001	0.999	0.000
T47.3 Saline and osmotic laxatives	0.001	0.999	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.999	0.001
T38.9 Other and unspecified hormone antagonists	0.001	0.999	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.999	0.000
T38.7 Androgens and anabolic congeners	0.001	0.999	0.000
T38.4 Oral contraceptives	0.001	0.999	0.000
T38.2 Antithyroid drugs	0.001	0.999	0.000
T41.5 Therapeutic gases	0.001	0.999	0.000
T41.4 Anaesthetic, unspecified	0.001	0.999	0.000
T41.3 Local anaesthetics	0.001	0.999	0.000
T41.2 Other and unspecified general anaesthetics	0.001	0.999	0.000
T41.1 Intravenous anaesthetics	0.001	0.999	0.000
T41.0 Inhaled anaesthetics	0.001	0.999	0.000
Z59.1 Inadequate housing	0.001	0.999	0.000
C64-C68 Malignant neoplasms of urinary tract	0.001	0.999	0.000
L81.7 Pigmented purpuric dermatosis	0.000	0.999	0.001
T50.6 Antidotes and chelating agents, not elsewhere classified	0.001	0.999	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.001	0.999	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.999	0.001
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.999	0.001
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.999	0.001
S62.30 Fracture of other metacarpal bone (closed)	0.001	0.999	0.000
F41.2 Mixed anxiety and depressive disorder	0.001	0.999	0.000
K11.6 Mucocele of salivary gland	0.000	0.999	0.001
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.999	0.001
R09.1 Pleurisy	0.000	0.999	0.001
T38.5 Other oestrogens and progestogens	0.001	0.999	0.000
M54.19 Radiculopathy (Site unspecified)	0.001	0.999	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.000	0.999	0.001
L81.6 Other disorders of diminished melanin formation	0.000	0.999	0.001
L81.5 Leukoderma, not elsewhere classified	0.000	0.999	0.001
L81.3 Cafe au lait spots	0.000	0.999	0.001
L81.1 Chloasma	0.000	0.999	0.001
T45.5 Anticoagulants	0.001	0.999	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.001	0.999	0.000
L65 Other nonscarring hair loss	0.000	0.999	0.001
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.001	0.999	0.000
M85.69 Other cyst of bone (Site unspecified)	0.000	0.999	0.001
M85.63 Other cyst of bone (Forearm)	0.000	0.999	0.001
M85.62 Other cyst of bone (Upper arm)	0.000	0.999	0.001
M85.61 Other cyst of bone (Shoulder region)	0.000	0.999	0.001
M85.60 Other cyst of bone (Multiple sites)	0.000	0.999	0.001
F43.0 Acute stress reaction	0.000	0.999	0.001
H40.2 Primary angle-closure glaucoma	0.001	0.999	0.000
L81.2 Freckles	0.000	0.999	0.001
T45.9 Primarily systemic and haematological agent, unspecified	0.001	0.999	0.000
T45.8 Other primarily systemic and haematological agents	0.001	0.999	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.999	0.000
T45.6 Fibrinolysis-affecting drugs	0.001	0.999	0.000
T45.4 Iron and its compounds	0.001	0.999	0.000
T45.3 Enzymes, not elsewhere classified	0.001	0.999	0.000
T45.2 Vitamins, not elsewhere classified	0.001	0.999	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.001	0.999	0.000
C68.0 Urethra	0.001	0.999	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.999	0.001
I07.8 Other tricuspid valve diseases	0.000	0.999	0.001
I07.2 Tricuspid stenosis with insufficiency	0.000	0.999	0.001
I07.0 Tricuspid stenosis	0.000	0.999	0.001
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.999	0.001
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.999	0.001
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.999	0.001
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.999	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.001	0.999	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.001	0.999	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations