TreeWAS – Variant ID: rs1727313

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M17.9 Gonarthrosis, unspecified	1.000	0.000	0.000
M17 Gonarthrosis [arthrosis of knee]	0.999	0.001	0.000
M17.1 Other primary gonarthrosis	0.999	0.001	0.000
M17.0 Primary gonarthrosis, bilateral	0.971	0.029	0.000
D25.9 Leiomyoma of uterus, unspecified	0.667	0.333	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.653	0.346	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.627	0.373	0.000
M17.3 Other posttraumatic gonarthrosis	0.618	0.382	0.000
M17.5 Other secondary gonarthrosis	0.543	0.457	0.000
G47.3 Sleep apnoea	0.147	0.853	0.000
G47 Sleep disorders	0.138	0.862	0.000
G47.9 Sleep disorder, unspecified	0.122	0.878	0.000
G47.4 Narcolepsy and cataplexy	0.118	0.882	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.115	0.885	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.112	0.887	0.000
G47.8 Other sleep disorders	0.110	0.890	0.000
G47.2 Disorders of the sleep-wake schedule	0.101	0.899	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.085	0.915	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.070	0.930	0.000
D25 Leiomyoma of uterus	0.067	0.933	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.063	0.937	0.000
M15-M19 Arthrosis	0.063	0.937	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.061	0.939	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.060	0.940	0.000
M15 Polyarthrosis	0.050	0.950	0.000
M15.8 Other polyarthrosis	0.041	0.959	0.000
D25.2 Subserosal leiomyoma of uterus	0.039	0.961	0.000
D25.0 Submucous leiomyoma of uterus	0.039	0.961	0.000
M15.4 Erosive (osteo)arthrosis	0.038	0.962	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.037	0.963	0.000
M15.0 Primary generalised (osteo)arthrosis	0.037	0.963	0.000
M15.9 Polyarthrosis, unspecified	0.036	0.963	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.036	0.964	0.000
M15.1 Heberden's nodes (with arthropathy)	0.035	0.965	0.000
M15.3 Secondary multiple arthrosis	0.034	0.966	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.033	0.967	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.027	0.973	0.000
M15.99 Polyosteoarthritis, unspecified	0.027	0.973	0.000
M19 Other arthrosis	0.024	0.976	0.000
M18 Arthrosis of first carpometacarpal joint	0.022	0.978	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.021	0.979	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.021	0.979	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.019	0.980	0.000
M19.0 Primary arthrosis of other joints	0.019	0.981	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.019	0.981	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.019	0.981	0.000
C50.1 Central portion of breast	0.000	0.981	0.019
T43.0 Tricyclic and tetracyclic antidepressants	0.018	0.982	0.000
T43.2 Other and unspecified antidepressants	0.018	0.982	0.000
M19.8 Other specified arthrosis	0.018	0.982	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.982	0.018
C50.4 Upper-outer quadrant of breast	0.000	0.983	0.017
M19.2 Other secondary arthrosis	0.017	0.983	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.017	0.983	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.016	0.984	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.016	0.984	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.016	0.984	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.016	0.984	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.016	0.984	0.000
T36 Poisoning by systemic antibiotics	0.016	0.984	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.016	0.984	0.000
T43.9 Psychotropic drug, unspecified	0.016	0.984	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.016	0.984	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.016	0.984	0.000
T43.6 Psychostimulants with abuse potential	0.015	0.984	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.015	0.984	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.015	0.985	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.015	0.985	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.015	0.985	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.015	0.985	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.015	0.985	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.015	0.985	0.000
T42.1 Iminostilbenes	0.015	0.985	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.015	0.985	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.015	0.985	0.000
C50 Malignant neoplasm of breast	0.000	0.985	0.015
M19.08 Primary arthrosis of other joints (Other)	0.014	0.985	0.000
T42.4 Benzodiazepines	0.014	0.986	0.000
N81.4 Uterovaginal prolapse, unspecified	0.014	0.986	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.014	0.986	0.000
T40.2 Other opioids	0.014	0.986	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.014	0.986	0.000
N81.9 Female genital prolapse, unspecified	0.014	0.986	0.000
M47.89 Other spondylosis (Site unspecified)	0.014	0.986	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.014	0.986	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.014	0.986	0.000
N81 Female genital prolapse	0.014	0.986	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.014	0.986	0.000
T42.2 Succinimides and oxazolidinediones	0.014	0.986	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.013	0.986	0.000
M75.4 Impingement syndrome of shoulder	0.014	0.986	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.013	0.987	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.013	0.987	0.000
D27 Benign neoplasm of ovary	0.000	0.987	0.013
M19.84 Other specified arthrosis (Hand)	0.013	0.987	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.013	0.987	0.000
T42.0 Hydantoin derivatives	0.013	0.987	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.013	0.987	0.000
T36.0 Penicillins	0.013	0.987	0.000
T48.5 Anti-common-cold drugs	0.013	0.987	0.000
N81.5 Vaginal enterocele	0.013	0.987	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.013	0.987	0.000
N81.2 Incomplete uterovaginal prolapse	0.013	0.987	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.013	0.987	0.000
M19.88 Other specified arthrosis (Other)	0.013	0.987	0.000
M19.86 Other specified arthrosis (Lower leg)	0.013	0.987	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.013	0.987	0.000
M19.83 Other specified arthrosis (Forearm)	0.013	0.987	0.000
M19.82 Other specified arthrosis (Upper arm)	0.013	0.987	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.013	0.987	0.000
T45.0 Antiallergic and antiemetic drugs	0.013	0.987	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.013	0.987	0.000
M47.82 Other spondylosis (Cervical region)	0.013	0.987	0.000
M19.23 Other secondary arthrosis (Forearm)	0.012	0.987	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.012	0.987	0.000
M19.28 Other secondary arthrosis (Other)	0.012	0.987	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.012	0.987	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.012	0.987	0.000
M19.24 Other secondary arthrosis (Hand)	0.012	0.987	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.012	0.987	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.012	0.987	0.000
M47.8 Other spondylosis	0.013	0.987	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.012	0.988	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.012	0.988	0.000
N81.8 Other female genital prolapse	0.012	0.988	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.012	0.988	0.000
T42.3 Barbiturates	0.012	0.988	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.012	0.988	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.012	0.988	0.000
T40.3 Methadone	0.012	0.988	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.012	0.988	0.000
T36.3 Macrolides	0.012	0.988	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.012	0.988	0.000
T36.4 Tetracyclines	0.012	0.988	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.012	0.988	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.012	0.988	0.000
T48.4 Expectorants	0.012	0.988	0.000
T48.3 Antitussives	0.012	0.988	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.012	0.988	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.012	0.988	0.000
T48.0 Oxytocic drugs	0.012	0.988	0.000
T45.2 Vitamins, not elsewhere classified	0.012	0.988	0.000
T50.8 Diagnostic agents	0.012	0.988	0.000
T36.9 Systemic antibiotic, unspecified	0.011	0.988	0.000
T36.7 Antifungal antibiotics, systemically used	0.011	0.988	0.000
T36.6 Rifamycins	0.011	0.988	0.000
T36.5 Aminoglycosides	0.011	0.988	0.000
T36.2 Chloramphenicol group	0.011	0.988	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.012	0.988	0.000
T40.5 Cocaine	0.011	0.988	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.011	0.988	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.011	0.988	0.000
T40.1 Heroin	0.011	0.988	0.000
T50.1 Loop [high-ceiling] diuretics	0.011	0.988	0.000
T36.8 Other systemic antibiotics	0.011	0.989	0.000
C50.0 Nipple and areola	0.000	0.989	0.011
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.011	0.989	0.000
T40.8 Lysergide [LSD]	0.011	0.989	0.000
T40.7 Cannabis (derivatives)	0.011	0.989	0.000
T40.0 Opium	0.011	0.989	0.000
C50.3 Lower-inner quadrant of breast	0.000	0.989	0.011
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.011	0.989	0.000
T47.0 Histamine H(2)-receptor antagonists	0.011	0.989	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.011	0.989	0.000
N81.0 Female urethrocele	0.011	0.989	0.000
T49.9 Topical agent, unspecified	0.011	0.989	0.000
T49.8 Other topical agents	0.011	0.989	0.000
T49.7 Dental drugs, topically applied	0.011	0.989	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.011	0.989	0.000
T49.5 Ophthalmological drugs and preparations	0.011	0.989	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.011	0.989	0.000
T49.3 Emollients, demulcents and protectants	0.011	0.989	0.000
T49.2 Local astringents and local detergents	0.011	0.989	0.000
T49.1 Antipruritics	0.011	0.989	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.011	0.989	0.000
T37.5 Antiviral drugs	0.011	0.989	0.000
T37.4 Anthelminthics	0.011	0.989	0.000
T37.3 Other antiprotozoal drugs	0.011	0.989	0.000
T37.1 Antimycobacterial drugs	0.011	0.989	0.000
T37.0 Sulphonamides	0.011	0.989	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.011	0.989	0.000
T45.8 Other primarily systemic and haematological agents	0.011	0.989	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.011	0.989	0.000
T45.6 Fibrinolysis-affecting drugs	0.011	0.989	0.000
T45.3 Enzymes, not elsewhere classified	0.011	0.989	0.000
T50.7 Analeptics and opioid receptor antagonists	0.011	0.989	0.000
T50.5 Appetite depressants	0.011	0.989	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.011	0.989	0.000
T50.0 Mineralocorticoids and their antagonists	0.011	0.989	0.000
M19.89 Other specified arthrosis (Site unspecified)	0.010	0.989	0.000
C50.5 Lower-outer quadrant of breast	0.000	0.989	0.011
M75.5 Bursitis of shoulder	0.011	0.989	0.000
T47.4 Other laxatives	0.010	0.989	0.000
T47.2 Stimulant laxatives	0.010	0.989	0.000
T45.5 Anticoagulants	0.010	0.989	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.010	0.990	0.000
C50.6 Axillary tail of breast	0.000	0.990	0.010
T50.4 Drugs affecting uric acid metabolism	0.010	0.990	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.010	0.990	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.010	0.990	0.000
T47.7 Emetics	0.010	0.990	0.000
T47.5 Digestants	0.010	0.990	0.000
T47.3 Saline and osmotic laxatives	0.010	0.990	0.000
T47.6 Antidiarrhoeal drugs	0.010	0.990	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.010	0.990	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.010	0.990	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.010	0.990	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.010	0.990	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.010	0.990	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.010	0.990	0.000
T44.0 Anticholinesterase agents	0.010	0.990	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.010	0.990	0.000
T45.4 Iron and its compounds	0.010	0.990	0.000
M19.1 Posttraumatic arthrosis of other joints	0.010	0.990	0.000
T40.6 Other and unspecified narcotics	0.010	0.990	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.010	0.990	0.000
M47.84 Other spondylosis (Thoracic region)	0.010	0.990	0.000
T41.5 Therapeutic gases	0.010	0.990	0.000
T41.4 Anaesthetic, unspecified	0.010	0.990	0.000
T41.3 Local anaesthetics	0.010	0.990	0.000
T41.1 Intravenous anaesthetics	0.010	0.990	0.000
T41.0 Inhaled anaesthetics	0.010	0.990	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.010	0.990	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.010	0.990	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.010	0.990	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.009	0.990	0.000
T41.2 Other and unspecified general anaesthetics	0.009	0.990	0.000
M23.4 Loose body in knee	0.009	0.991	0.000
M23 Internal derangement of knee	0.009	0.991	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.009	0.991	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.009	0.991	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.009	0.991	0.000
T40.4 Other synthetic narcotics	0.009	0.991	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.009	0.991	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.009	0.991	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.009	0.991	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.009	0.991	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.009	0.991	0.000
M47 Spondylosis	0.009	0.991	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.009	0.991	0.000
M20.3 Other deformity of hallux (acquired)	0.009	0.991	0.000
M20 Acquired deformities of fingers and toes	0.009	0.991	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.009	0.991	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.009	0.991	0.000
T46.7 Peripheral vasodilators	0.009	0.991	0.000
M25.76 Osteophyte (Lower leg)	0.009	0.991	0.000
M20.0 Deformity of finger(s)	0.009	0.991	0.000
M23.43 Loose body in knee-Med lig/oth men	0.009	0.991	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.009	0.991	0.000
M75 Shoulder lesions	0.009	0.991	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.008	0.991	0.000
M00-M03 Infectious arthropathies	0.008	0.992	0.000
M70-M79 Other soft tissue disorders	0.008	0.992	0.000
D25.1 Intramural leiomyoma of uterus	0.008	0.992	0.000
N81.3 Complete uterovaginal prolapse	0.008	0.992	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.008	0.992	0.000
M43.1 Spondylolisthesis	0.008	0.992	0.000
M71 Other bursopathies	0.008	0.992	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.008	0.992	0.000
M20.1 Hallux valgus (acquired)	0.008	0.992	0.000
M45-M49 Spondylopathies	0.008	0.992	0.000
T46.1 Calcium-channel blockers	0.008	0.992	0.000
M23.3 Other meniscus derangements	0.008	0.992	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.008	0.992	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.008	0.992	0.000
M40-M43 Deforming dorsopathies	0.008	0.992	0.000
M23.46 Loose body in knee-O/unsp lat men	0.008	0.992	0.000
M20.4 Other hammer toe(s) (acquired)	0.008	0.992	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.008	0.992	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.008	0.992	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.008	0.992	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.008	0.992	0.000
M43 Other deforming dorsopathies	0.007	0.992	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.007	0.993	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.007	0.993	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.007	0.993	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.007	0.993	0.000
M20-M25 Other joint disorders	0.007	0.993	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.007	0.993	0.000
M23.49 Loose body in knee-Unspec lig/men	0.007	0.993	0.000
M00 Pyogenic arthritis	0.007	0.993	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.007	0.993	0.000
M23.1 Discoid meniscus (congenital)	0.007	0.993	0.000
M23.40 Loose body in knee-Mult sites	0.007	0.993	0.000
I83 Varicose veins of lower extremities	0.000	0.993	0.007
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.007	0.993	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.007	0.993	0.000
D24 Benign neoplasm of breast	0.007	0.993	0.000
T38.9 Other and unspecified hormone antagonists	0.007	0.993	0.000
T38.7 Androgens and anabolic congeners	0.007	0.993	0.000
T38.4 Oral contraceptives	0.007	0.993	0.000
T38.2 Antithyroid drugs	0.007	0.993	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.007	0.993	0.000
M47.2 Other spondylosis with radiculopathy	0.007	0.993	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.007	0.993	0.000
M71.3 Other bursal cyst	0.007	0.993	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.007	0.993	0.000
T38.0 Glucocorticoids and synthetic analogues	0.007	0.993	0.000
M60-M63 Disorders of muscles	0.007	0.993	0.000
M23.8 Other internal derangements of knee	0.007	0.993	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.007	0.993	0.000
N81.1 Cystocele	0.007	0.993	0.000
M23.47 Loose body in knee-Capsular lig	0.007	0.993	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.007	0.993	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.007	0.993	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.007	0.993	0.000
G40-G47 Episodic and paroxysmal disorders	0.007	0.993	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.007	0.993	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.007	0.993	0.000
M25.77 Osteophyte (Ankle and foot)	0.007	0.993	0.000
C50.8 Overlapping lesion of breast	0.000	0.993	0.007
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.993	0.007
M89 Other disorders of bone	0.007	0.993	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.006	0.993	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.007	0.993	0.000
T38.5 Other oestrogens and progestogens	0.006	0.993	0.000
M02 Reactive arthropathies	0.007	0.993	0.000
M71.38 Other bursal cyst (Other)	0.007	0.993	0.000
M23.9 Internal derangement of knee, unspecified	0.007	0.993	0.000
M86-M90 Other osteopathies	0.007	0.993	0.000
M89.0 Algoneurodystrophy	0.007	0.993	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.007	0.993	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.007	0.993	0.000
M22 Disorders of patella	0.007	0.993	0.000
M22.3 Other derangements of patella	0.007	0.993	0.000
M76 Enthesopathies of lower limb, excluding foot	0.007	0.993	0.000
M47.1 Other spondylosis with myelopathy	0.007	0.993	0.000
C50.9 Breast, unspecified	0.000	0.993	0.007
T38.1 Thyroid hormones and substitutes	0.006	0.993	0.000
C50.2 Upper-inner quadrant of breast	0.000	0.993	0.006
M23.41 Loose body in knee-Ant lig/hrn men	0.006	0.994	0.000
M45 Ankylosing spondylitis	0.006	0.994	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.006	0.994	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.006	0.994	0.000
M71.0 Abscess of bursa	0.006	0.994	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.006	0.994	0.000
M23.0 Cystic meniscus	0.006	0.994	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.006	0.994	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.006	0.994	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.006	0.994	0.000
M65-M68 Disorders of synovium and tendon	0.006	0.994	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.006	0.994	0.000
M25.7 Osteophyte	0.006	0.994	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.006	0.994	0.000
M43.12 Spondylolisthesis (Cervical region)	0.006	0.994	0.000
M00.9 Pyogenic arthritis, unspecified	0.006	0.994	0.000
C50-C50 Malignant neoplasm of breast	0.000	0.994	0.006
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.006	0.994	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.006	0.994	0.000
M89.8 Other specified disorders of bone	0.006	0.994	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.006	0.994	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.006	0.994	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.006	0.994	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.006	0.994	0.000
M43.0 Spondylolysis	0.006	0.994	0.000
M71.8 Other specified bursopathies	0.006	0.994	0.000
M71.5 Other bursitis, not elsewhere classified	0.006	0.994	0.000
M75.8 Other shoulder lesions	0.006	0.994	0.000
M71.4 Calcium deposit in bursa	0.006	0.994	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
M40 Kyphosis and lordosis	0.006	0.994	0.000
M60 Myositis	0.006	0.994	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.006	0.994	0.000
M23.5 Chronic instability of knee	0.006	0.994	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.006	0.994	0.000
M70.5 Other bursitis of knee	0.006	0.994	0.000
M23.37 Other meniscus derangements-Capsular lig	0.006	0.994	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.005	0.994	0.001
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.006	0.994	0.000
M32 Systemic lupus erythematosus	0.006	0.994	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.006	0.994	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.006	0.994	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.994	0.006
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.006	0.994	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.006	0.994	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.006	0.994	0.000
M70.3 Other bursitis of elbow	0.006	0.994	0.000
M89.5 Osteolysis	0.006	0.994	0.000
M71.29 Synovial cyst of popliteal space [Baker]-Site unspec	0.006	0.994	0.000
M71.28 Synovial cyst of popliteal space [Baker]-Other	0.006	0.994	0.000
M71.27 Synovial cyst of popliteal space [Baker]-Ankle/Foot	0.006	0.994	0.000
M71.25 Synovial cyst of popliteal space [Baker]-Pelvic/Thigh	0.006	0.994	0.000
M71.24 Synovial cyst of popliteal space [Baker]-Hand	0.006	0.994	0.000
M71.23 Synovial cyst of popliteal space [Baker]-Forearm	0.006	0.994	0.000
M71.22 Synovial cyst of popliteal space [Baker]-Upper arm	0.006	0.994	0.000
M71.21 Synovial cyst of popliteal space [Baker]-Shldr region	0.006	0.994	0.000
M71.20 Synovial cyst of popliteal space [Baker]-Mult sites	0.006	0.994	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.006	0.994	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.006	0.994	0.000
M43.9 Deforming dorsopathy, unspecified	0.006	0.994	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.006	0.994	0.000
M71.9 Bursopathy, unspecified	0.006	0.994	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.006	0.994	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.005	0.994	0.000
G44.0 Cluster headache syndrome	0.006	0.994	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.006	0.994	0.000
M43.5 Other recurrent vertebral subluxation	0.005	0.994	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.005	0.994	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.005	0.994	0.000
G44 Other headache syndromes	0.006	0.994	0.000
M02.9 Reactive arthopathy, unspecified	0.005	0.994	0.000
M70.0 Chronic crepitant synovitis of hand and wrist	0.006	0.994	0.000
M42 Spinal osteochondrosis	0.005	0.994	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.006	0.994	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.006	0.994	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.005	0.994	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.005	0.994	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.005	0.994	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.005	0.994	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.005	0.994	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.005	0.994	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.005	0.994	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.005	0.994	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.005	0.994	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.005	0.994	0.000
M43.8 Other specified deforming dorsopathies	0.005	0.994	0.000
M22.0 Recurrent dislocation of patella	0.005	0.994	0.000
M71.37 Other bursal cyst (Ankle and foot)	0.005	0.994	0.000
M89.04 Algoneurodystrophy (Hand)	0.005	0.994	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.005	0.994	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.005	0.994	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.005	0.994	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.005	0.994	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.005	0.994	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.005	0.994	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.005	0.994	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.005	0.994	0.000
M22.8 Other disorders of patella	0.005	0.994	0.000
M24.1 Other articular cartilage disorders	0.005	0.994	0.000
M67 Other disorders of synovium and tendon	0.005	0.994	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.005	0.995	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.005	0.995	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.005	0.995	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.005	0.995	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.005	0.995	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.005	0.995	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.005	0.995	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.005	0.995	0.000
M70.7 Other bursitis of hip	0.005	0.995	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.005	0.995	0.000
M67.1 Other contracture of tendon (sheath)	0.005	0.995	0.000
M24 Other specific joint derangements	0.005	0.995	0.000
M71.39 Other bursal cyst (Site unspecified)	0.005	0.995	0.000
M71.36 Other bursal cyst (Lower leg)	0.005	0.995	0.000
M71.35 Other bursal cyst (Pelvic region and thigh)	0.005	0.995	0.000
M71.33 Other bursal cyst (Forearm)	0.005	0.995	0.000
M71.32 Other bursal cyst (Upper arm)	0.005	0.995	0.000
M71.31 Other bursal cyst (Shoulder region)	0.005	0.995	0.000
M71.30 Other bursal cyst (Multiple sites)	0.005	0.995	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.995	0.005
I08 Multiple valve diseases	0.000	0.995	0.005
M63 Disorders of muscle in diseases classified elsewhere	0.005	0.995	0.000
M61 Calcification and ossification of muscle	0.005	0.995	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.005	0.995	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.005	0.995	0.000
D13.2 Duodenum	0.005	0.995	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.995	0.005
M70.6 Trochanteric bursitis	0.005	0.995	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.005	0.995	0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.005	0.995	0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.005	0.995	0.000
M70.1 Bursitis of hand	0.005	0.995	0.000
M76.1 Psoas tendinitis	0.005	0.995	0.000
M76.0 Gluteal tendinitis	0.005	0.995	0.000
M49 Spondylopathies in diseases classified elsewhere	0.005	0.995	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.005	0.995	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.005	0.995	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
M70.56 Other bursitis of knee-Lower Leg	0.005	0.995	0.000
M71.06 Abscess of bursa (Lower leg)	0.005	0.995	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.005	0.995	0.000
M02.3 Reiter's disease	0.005	0.995	0.000
M66 Spontaneous rupture of synovium and tendon	0.005	0.995	0.000
M71.1 Other infective bursitis	0.005	0.995	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.005	0.995	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.005	0.995	0.000
M89.6 Osteopathy after poliomyelitis	0.005	0.995	0.000
M89.2 Other disorders of bone development and growth	0.005	0.995	0.000
M89.1 Epiphyseal arrest	0.005	0.995	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.005	0.995	0.000
M02.8 Other reactive arthropathies	0.005	0.995	0.000
M02.2 Postimmunisation arthropathy	0.005	0.995	0.000
M02.1 Postdysenteric arthropathy	0.005	0.995	0.000
M02.0 Arthropathy following intestinal bypass	0.005	0.995	0.000
M25.79 Osteophyte (Site unspecified)	0.005	0.995	0.000
M76.5 Patellar tendinitis	0.005	0.995	0.000
M90 Osteopathies in diseases classified elsewhere	0.005	0.995	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.005	0.995	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.005	0.995	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.005	0.995	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.005	0.995	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.005	0.995	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.005	0.995	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.005	0.995	0.000
M89.08 Algoneurodystrophy (Other)	0.005	0.995	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.005	0.995	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.005	0.995	0.000
M25.71 Osteophyte (Shoulder region)	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations