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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17333649
log Bayes Factor = 6.63712
Chromosome 2   position 5,379,187  (GRCh37) Explore rs17333649 on Ensembl!
Variant rs17333649 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
Chapter X Diseases of the respiratory system
0.987 0.013 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.982 0.018 0.000
Chapter VII Diseases of the eye and adnexa
0.976 0.024 0.000
J95-J99 Other diseases of the respiratory system
0.976 0.024 0.000
Chapter VI Diseases of the nervous system
0.966 0.034 0.000
J98 Other respiratory disorders
0.965 0.035 0.000
K70-K77 Diseases of liver
0.959 0.041 0.000
M20-M25 Other joint disorders
0.955 0.045 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.954 0.046 0.000
Chapter II Neoplasms
0.951 0.049 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.943 0.057 0.000
I30-I52 Other forms of heart disease
0.941 0.059 0.000
Chapter V Mental and behavioural disorders
0.939 0.061 0.000
Chapter IX Diseases of the circulatory system
0.934 0.066 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.932 0.068 0.000
I44 Atrioventricular and left bundle-branch block
0.920 0.080 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.920 0.080 0.000
Chapter VIII Diseases of the ear and mastoid process
0.918 0.082 0.000
J98.1 Pulmonary collapse
0.917 0.083 0.000
J20-J22 Other acute lower respiratory infections
0.917 0.083 0.000
J98.4 Other disorders of lung
0.917 0.083 0.000
I34 Nonrheumatic mitral valve disorders
0.915 0.085 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.915 0.085 0.000
M15-M19 Arthrosis
0.914 0.086 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.910 0.090 0.000
M17 Gonarthrosis [arthrosis of knee]
0.909 0.091 0.000
H43-H45 Disorders of vitreous body and globe
0.907 0.093 0.000
K01 Embedded and impacted teeth
0.905 0.095 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.904 0.096 0.000
I50 Heart failure
0.901 0.099 0.000
M17.9 Gonarthrosis, unspecified
0.899 0.101 0.000
K70 Alcoholic liver disease
0.897 0.103 0.000
K55-K64 Other diseases of intestines
0.896 0.104 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.891 0.109 0.000
C64-C68 Malignant neoplasms of urinary tract
0.889 0.111 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.884 0.116 0.000
M25 Other joint disorders, not elsewhere classified
0.883 0.117 0.000
H90-H95 Other disorders of ear
0.882 0.118 0.000
E65-E68 Obesity and other hyperalimentation
0.877 0.123 0.000
I44.2 Atrioventricular block, complete
0.875 0.125 0.000
M05-M14 Inflammatory polyarthropathies
0.874 0.126 0.000
E66 Obesity
0.873 0.127 0.000
O00-O08 Pregnancy with abortive outcome
0.871 0.129 0.000
I34.0 Mitral (valve) insufficiency
0.869 0.131 0.000
D00-D09 In situ neoplasms
0.868 0.132 0.000
J22 Unspecified acute lower respiratory infection
0.868 0.132 0.000
C67 Malignant neoplasm of bladder
0.867 0.133 0.000
E66.9 Obesity, unspecified
0.867 0.133 0.000
G20-G26 Extrapyramidal and movement disorders
0.866 0.134 0.000
M23 Internal derangement of knee
0.865 0.135 0.000
H91 Other hearing loss
0.859 0.141 0.000
I44.7 Left bundle-branch block, unspecified
0.856 0.144 0.000
K50-K52 Noninfective enteritis and colitis
0.856 0.144 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.856 0.144 0.000
K01.1 Impacted teeth
0.851 0.149 0.000
M17.1 Other primary gonarthrosis
0.847 0.153 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.846 0.154 0.000
H43 Disorders of vitreous body
0.845 0.155 0.000
K63 Other diseases of intestine
0.843 0.156 0.000
H91.9 Hearing loss, unspecified
0.842 0.158 0.000
K63.5 Polyp of colon
0.841 0.159 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.840 0.160 0.000
K14 Diseases of tongue
0.839 0.161 0.000
C67.9 Bladder, unspecified
0.839 0.161 0.000
F10.3 Withdrawal state
0.835 0.165 0.000
F10.2 Dependence syndrome
0.833 0.167 0.000
J09-J18 Influenza and pneumonia
0.832 0.168 0.000
R30-R39 Symptoms and signs involving the urinary system
0.829 0.171 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.828 0.172 0.000
K75 Other inflammatory liver diseases
0.826 0.174 0.000
R33 Retention of urine
0.824 0.176 0.000
M80-M85 Disorders of bone density and structure
0.823 0.177 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.820 0.180 0.000
I34.1 Mitral (valve) prolapse
0.814 0.186 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.813 0.187 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.810 0.190 0.000
G20 Parkinson's disease
0.808 0.192 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.808 0.192 0.000
H30-H36 Disorders of choroid and retina
0.806 0.194 0.000
H55-H59 Other disorders of eye and adnexa
0.806 0.194 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.806 0.194 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.803 0.197 0.000
F10.1 Harmful use
0.802 0.198 0.000
I50.0 Congestive heart failure
0.800 0.200 0.000
K08 Other disorders of teeth and supporting structures
0.800 0.200 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.800 0.200 0.000
I38 Endocarditis, valve unspecified
0.799 0.201 0.000
T39.1 4-Aminophenol derivatives
0.799 0.201 0.000
K40-K46 Hernia
0.797 0.203 0.000
M91-M94 Chondropathies
0.795 0.205 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.792 0.208 0.000
O02 Other abnormal products of conception
0.792 0.208 0.000
M86-M90 Other osteopathies
0.791 0.209 0.000
M31 Other necrotising vasculopathies
0.790 0.209 0.000
D03 Melanoma in situ
0.789 0.211 0.000
K13 Other diseases of lip and oral mucosa
0.787 0.213 0.000
K60 Fissure and fistula of anal and rectal regions
0.787 0.213 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.787 0.213 0.000
O80-O84 Delivery
0.787 0.213 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.786 0.214 0.000
S70-S79 Injuries to the hip and thigh
0.784 0.216 0.000
R32 Unspecified urinary incontinence
0.779 0.221 0.000
I51 Complications and ill-defined descriptions of heart disease
0.777 0.223 0.000
K72 Hepatic failure, not elsewhere classified
0.776 0.224 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.776 0.224 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.776 0.224 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.774 0.226 0.000
D41.4 Bladder
0.773 0.227 0.000
K70.1 Alcoholic hepatitis
0.773 0.227 0.000
F10.0 Acute intoxication
0.772 0.228 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.771 0.229 0.000
O60-O75 Complications of labour and delivery
0.768 0.232 0.000
D45 Polycythaemia vera
0.768 0.232 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.768 0.232 0.000
K05 Gingivitis and periodontal diseases
0.767 0.233 0.000
I50.1 Left ventricular failure
0.765 0.235 0.000
I50.9 Heart failure, unspecified
0.764 0.236 0.000
K12 Stomatitis and related lesions
0.763 0.237 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.763 0.237 0.000
M06 Other rheumatoid arthritis
0.760 0.240 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.760 0.240 0.000
G90-G99 Other disorders of the nervous system
0.757 0.243 0.000
I30 Acute pericarditis
0.755 0.244 0.000
Chapter XIV Diseases of the genitourinary system
0.753 0.247 0.000
Chapter XXII Codes for special purposes
0.753 0.247 0.000
G35 Multiple sclerosis
0.752 0.248 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.752 0.248 0.000
H43.8 Other disorders of vitreous body
0.752 0.248 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.752 0.248 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.750 0.250 0.000
M24 Other specific joint derangements
0.749 0.251 0.000
M25.5 Pain in joint
0.748 0.252 0.000
K70.3 Alcoholic cirrhosis of liver
0.747 0.253 0.000
I33 Acute and subacute endocarditis
0.746 0.254 0.000
M25.4 Effusion of joint
0.746 0.254 0.000
K70.9 Alcoholic liver disease, unspecified
0.746 0.254 0.000
C85.1 B-cell lymphoma, unspecified
0.745 0.255 0.000
D09 Carcinoma in situ of other and unspecified sites
0.745 0.255 0.000
S20-S29 Injuries to the thorax
0.744 0.256 0.000
E66.8 Other obesity
0.742 0.258 0.000
K10 Other diseases of jaws
0.741 0.259 0.000
K09 Cysts of oral region, not elsewhere classified
0.740 0.260 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.739 0.261 0.000
M21 Other acquired deformities of limbs
0.739 0.261 0.000
I42 Cardiomyopathy
0.738 0.262 0.000
K14.8 Other diseases of tongue
0.738 0.262 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.735 0.264 0.000
K55 Vascular disorders of intestine
0.735 0.265 0.000
O02.1 Missed abortion
0.735 0.265 0.000
C91 Lymphoid leukaemia
0.729 0.271 0.000
O03 Spontaneous abortion
0.728 0.272 0.000
F10.4 Withdrawal state with delirium
0.727 0.273 0.000
J60-J70 Lung diseases due to external agents
0.725 0.275 0.000
S90-S99 Injuries to the ankle and foot
0.724 0.276 0.000
K50 Crohn's disease [regional enteritis]
0.724 0.276 0.000
K85 Acute pancreatitis
0.724 0.276 0.000
M22 Disorders of patella
0.724 0.276 0.000
J98.8 Other specified respiratory disorders
0.723 0.277 0.000
N25-N29 Other disorders of kidney and ureter
0.722 0.278 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.722 0.278 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.722 0.278 0.000
H10-H13 Disorders of conjunctiva
0.718 0.282 0.000
K60.2 Anal fissure, unspecified
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.717 0.283 0.000
K07 Dentofacial anomalies [including malocclusion]
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.714 0.286 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.713 0.287 0.000
H43.3 Other vitreous opacities
0.712 0.288 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.712 0.288 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.711 0.288 0.000
M60-M63 Disorders of muscles
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
C88 Malignant immunoproliferative diseases
0.709 0.291 0.000
N00-N08 Glomerular diseases
0.708 0.292 0.000
G57 Mononeuropathies of lower limb
0.707 0.293 0.000
H01 Other inflammation of eyelid
0.706 0.294 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.706 0.294 0.000
D04 Carcinoma in situ of skin
0.705 0.295 0.000
I36 Nonrheumatic tricuspid valve disorders
0.704 0.296 0.000
K04 Diseases of pulp and periapical tissues
0.704 0.296 0.000
K42 Umbilical hernia
0.704 0.296 0.000
C92 Myeloid leukaemia
0.704 0.296 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.704 0.296 0.000
K03 Other diseases of hard tissues of teeth
0.704 0.296 0.000
K00 Disorders of tooth development and eruption
0.704 0.296 0.000
J90-J94 Other diseases of pleura
0.703 0.297 0.000
H35 Other retinal disorders
0.702 0.298 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.701 0.299 0.000
H44 Disorders of globe
0.701 0.299 0.000
H60-H62 Diseases of external ear
0.700 0.300 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.700 0.300 0.000
J96 Respiratory failure, not elsewhere classified
0.700 0.300 0.000
T39.0 Salicylates
0.699 0.301 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.699 0.301 0.000
K86 Other diseases of pancreas
0.699 0.301 0.000
K76 Other diseases of liver
0.697 0.303 0.000
K02 Dental caries
0.695 0.305 0.000
R26 Abnormalities of gait and mobility
0.695 0.305 0.000
F80-F89 Disorders of psychological development
0.694 0.305 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.694 0.306 0.000
J98.9 Respiratory disorder, unspecified
0.692 0.308 0.000
J98.6 Disorders of diaphragm
0.692 0.308 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.692 0.308 0.000
J98.3 Compensatory emphysema
0.692 0.308 0.000
J98.2 Interstitial emphysema
0.692 0.308 0.000
K56.1 Intussusception
0.691 0.309 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.690 0.310 0.000
J11 Influenza, virus not identified
0.689 0.311 0.000
M05 Seropositive rheumatoid arthritis
0.689 0.311 0.000
T79-T79 Certain early complications of trauma
0.688 0.312 0.000
K77 Liver disorders in diseases classified elsewhere
0.687 0.312 0.000
K73 Chronic hepatitis, not elsewhere classified
0.687 0.312 0.000
K71 Toxic liver disease
0.687 0.312 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.687 0.313 0.000
M65-M68 Disorders of synovium and tendon
0.686 0.314 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.685 0.315 0.000
M34 Systemic sclerosis
0.685 0.315 0.000
M33 Dermatopolymyositis
0.685 0.315 0.000
M32 Systemic lupus erythematosus
0.685 0.315 0.000
M30 Polyarteritis nodosa and related conditions
0.685 0.315 0.000
G70-G73 Diseases of myoneural junction and muscle
0.685 0.315 0.000
T33-T35 Frostbite
0.684 0.316 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.684 0.316 0.000
T00-T07 Injuries involving multiple body regions
0.684 0.316 0.000
S10-S19 Injuries to the neck
0.684 0.316 0.000
E50-E64 Other nutritional deficiencies
0.684 0.316 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.683 0.317 0.000
C67.6 Ureteric orifice
0.682 0.318 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.682 0.318 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.682 0.318 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.682 0.318 0.000
K51 Ulcerative colitis
0.681 0.319 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.681 0.319 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.678 0.322 0.000
M25.8 Other specified joint disorders
0.678 0.322 0.000
I44.3 Other and unspecified atrioventricular block
0.677 0.322 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.677 0.323 0.000
O85-O92 Complications predominantly related to the puerperium
0.676 0.324 0.000
F60-F69 Disorders of adult personality and behaviour
0.675 0.325 0.000
I52 Other heart disorders in diseases classified elsewhere
0.674 0.326 0.000
I48 Atrial fibrillation and flutter
0.674 0.326 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.674 0.326 0.000
I41 Myocarditis in diseases classified elsewhere
0.674 0.326 0.000
I40 Acute myocarditis
0.674 0.326 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.674 0.326 0.000
I37 Pulmonary valve disorders
0.674 0.326 0.000
I32 Pericarditis in diseases classified elsewhere
0.674 0.326 0.000
F99-F99 Unspecified mental disorder
0.673 0.327 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.673 0.327 0.000
F70-F79 Mental retardation
0.673 0.327 0.000
I49 Other cardiac arrhythmias
0.673 0.327 0.000
C67.4 Posterior wall of bladder
0.671 0.329 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.671 0.329 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.671 0.329 0.000
G37 Other demyelinating diseases of central nervous system
0.671 0.329 0.000
I00-I02 Acute rheumatic fever
0.669 0.331 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.669 0.331 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.668 0.331 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.668 0.331 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.668 0.331 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.668 0.331 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.668 0.331 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.668 0.331 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.668 0.331 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.668 0.331 0.000
T36 Poisoning by systemic antibiotics
0.668 0.331 0.000
G30-G32 Other degenerative diseases of the nervous system
0.668 0.332 0.000
M40-M43 Deforming dorsopathies
0.667 0.332 0.000
N60-N64 Disorders of breast
0.667 0.333 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.667 0.333 0.000
J10 Influenza due to identified influenza virus
0.667 0.333 0.000
K56.2 Volvulus
0.667 0.333 0.000
M31.3 Wegener's granulomatosis
0.666 0.334 0.000
I05-I09 Chronic rheumatic heart diseases
0.666 0.334 0.000
S60-S69 Injuries to the wrist and hand
0.666 0.334 0.000
M84 Disorders of continuity of bone
0.665 0.335 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.665 0.335 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.665 0.335 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.664 0.336 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.663 0.337 0.000
O80 Single spontaneous delivery
0.663 0.337 0.000
S72 Fracture of femur
0.662 0.337 0.000
S40-S49 Injuries to the shoulder and upper arm
0.661 0.339 0.000
H52 Disorders of refraction and accommodation
0.661 0.339 0.000
I44.6 Other and unspecified fascicular block
0.660 0.340 0.000
I44.5 Left posterior fascicular block
0.660 0.340 0.000
I44.4 Left anterior fascicular block
0.660 0.340 0.000
M06.9 Rheumatoid arthritis, unspecified
0.660 0.340 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.660 0.340 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.660 0.340 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.660 0.340 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.660 0.340 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.660 0.340 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.660 0.340 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.660 0.340 0.000
F11 Mental and behavioural disorders due to use of opioids
0.660 0.340 0.000
F20 Schizophrenia
0.659 0.341 0.000
M13 Other arthritis
0.659 0.341 0.000
E20-E35 Disorders of other endocrine glands
0.659 0.341 0.000
N03 Chronic nephritic syndrome
0.658 0.342 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.658 0.342 0.000
J21 Acute bronchiolitis
0.658 0.342 0.000
J20 Acute bronchitis
0.658 0.342 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.657 0.342 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.657 0.343 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.657 0.343 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.657 0.343 0.000
D09.0 Bladder
0.656 0.344 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.656 0.344 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.656 0.344 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.656 0.344 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.656 0.344 0.000
F10.9 Unspecified mental and behavioural disorder
0.656 0.344 0.000
F10.8 Other mental and behavioural disorders
0.656 0.344 0.000
F10.7 Residual and late-onset psychotic disorder
0.656 0.344 0.000
F10.6 Amnesic syndrome
0.656 0.344 0.000
F10.5 Psychotic disorder
0.656 0.344 0.000
M15 Polyarthrosis
0.655 0.345 0.000
D10-D36 Benign neoplasms
0.655 0.345 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.655 0.345 0.000
K75.9 Inflammatory liver disease, unspecified
0.655 0.345 0.000
I51.7 Cardiomegaly
0.655 0.345 0.000
N28.1 Cyst of kidney, acquired
0.655 0.345 0.000
H21 Other disorders of iris and ciliary body
0.655 0.345 0.000
M25.56 Pain in joint (Lower leg)
0.654 0.346 0.000
K75.8 Other specified inflammatory liver diseases
0.652 0.347 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.652 0.348 0.000
C95 Leukaemia of unspecified cell type
0.652 0.348 0.000
C94 Other leukaemias of specified cell type
0.652 0.348 0.000
C93 Monocytic leukaemia
0.652 0.348 0.000
C86 Other specified types of T/NK-cell lymphoma
0.652 0.348 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.652 0.348 0.000
C81 Hodgkin's disease
0.652 0.348 0.000
H04 Disorders of lachrymal system
0.652 0.348 0.000
K75.4 Autoimmune hepatitis
0.652 0.348 0.000
M17.5 Other secondary gonarthrosis
0.652 0.348 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.652 0.348 0.000
M17.3 Other posttraumatic gonarthrosis
0.652 0.348 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.652 0.348 0.000
D46 Myelodysplastic syndromes
0.651 0.349 0.000
G57.6 Lesion of plantar nerve
0.650 0.350 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.650 0.350 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.650 0.350 0.000
I44.0 Atrioventricular block, first degree
0.649 0.350 0.000
K01.0 Embedded teeth
0.649 0.351 0.000
K43 Ventral hernia
0.649 0.351 0.000
K90-K93 Other diseases of the digestive system
0.649 0.351 0.000
M80 Osteoporosis with pathological fracture
0.648 0.352 0.000
H55 Nystagmus and other irregular eye movements
0.648 0.352 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.648 0.352 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.648 0.352 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.648 0.352 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.648 0.352 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.648 0.352 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.648 0.352 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.647 0.353 0.000
K72.9 Hepatic failure, unspecified
0.645 0.354 0.000
R25 Abnormal involuntary movements
0.644 0.356 0.000
K70.4 Alcoholic hepatic failure
0.643 0.357 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.643 0.357 0.000
K70.0 Alcoholic fatty liver
0.643 0.357 0.000
N63 Unspecified lump in breast
0.643 0.357 0.000
R30 Pain associated with micturition
0.643 0.357 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.642 0.357 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.642 0.357 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.642 0.358 0.000
H43.1 Vitreous haemorrhage
0.642 0.358 0.000
M25.46 Effusion of joint (Lower leg)
0.641 0.359 0.000
N28.8 Other specified disorders of kidney and ureter
0.641 0.359 0.000
C67.2 Lateral wall of bladder
0.641 0.359 0.000
H93 Other disorders of ear, not elsewhere classified
0.641 0.359 0.000
T66-T78 Other and unspecified effects of external causes
0.641 0.359 0.000
J00-J06 Acute upper respiratory infections
0.641 0.359 0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa
0.639 0.361 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.639 0.361 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.639 0.361 0.000
T39.4 Antirheumatics, not elsewhere classified
0.639 0.361 0.000
T39.2 Pyrazolone derivatives
0.639 0.361 0.000
K58 Irritable bowel syndrome
0.639 0.361 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.639 0.361 0.000
G40-G47 Episodic and paroxysmal disorders
0.638 0.362 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.638 0.362 0.000
C66 Malignant neoplasm of ureter
0.638 0.362 0.000
C65 Malignant neoplasm of renal pelvis
0.638 0.362 0.000
K55.2 Angiodysplasia of colon
0.637 0.363 0.000
M93 Other osteochondropathies
0.637 0.363 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.636 0.364 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.635 0.365 0.000
Chapter XX External causes of morbidity and mortality
0.635 0.365 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.635 0.365 0.000
K14.0 Glossitis
0.634 0.366 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.634 0.366 0.000
E40-E46 Malnutrition
0.634 0.366 0.000
K40 Inguinal hernia
0.633 0.367 0.000
I60-I69 Cerebrovascular diseases
0.633 0.367 0.000
M25.9 Joint disorder, unspecified
0.633 0.367 0.000
M25.3 Other instability of joint
0.633 0.367 0.000
M25.2 Flail joint
0.633 0.367 0.000
M25.1 Fistula of joint
0.633 0.367 0.000
M25.0 Haemarthrosis
0.633 0.367 0.000
J95.8 Other postprocedural respiratory disorders
0.632 0.368 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.632 0.368 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.632 0.368 0.000
H01.0 Blepharitis
0.632 0.368 0.000
M11 Other crystal arthropathies
0.630 0.370 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.629 0.371 0.000
E67 Other hyperalimentation
0.629 0.371 0.000
E68 Sequelae of hyperalimentation
0.629 0.371 0.000
E65 Localised adiposity
0.629 0.371 0.000
H00 Hordeolum and chalazion
0.629 0.371 0.000
M89 Other disorders of bone
0.629 0.371 0.000
C83.0 Small cell (diffuse)
0.629 0.371 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.629 0.371 0.000
M25.57 Pain in joint (Ankle and foot)
0.627 0.373 0.000
G24 Dystonia
0.627 0.373 0.000
M14 Arthropathies in other diseases classified elsewhere
0.627 0.373 0.000
M12 Other specific arthropathies
0.627 0.373 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.627 0.373 0.000
M08 Juvenile arthritis
0.627 0.373 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.626 0.374 0.000
E66.1 Drug-induced obesity
0.626 0.374 0.000
E66.0 Obesity due to excess calories
0.626 0.374 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.625 0.375 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.624 0.376 0.000
O07 Failed attempted abortion
0.624 0.376 0.000
O06 Unspecified abortion
0.624 0.376 0.000
O05 Other abortion
0.624 0.376 0.000
O01 Hydatidiform mole
0.624 0.376 0.000
N03.9 Unspecified
0.623 0.377 0.000
I30.9 Acute pericarditis, unspecified
0.623 0.377 0.000
O00 Ectopic pregnancy
0.623 0.377 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.622 0.377 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.622 0.377 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.622 0.377 0.000
C67.8 Overlapping lesion of bladder
0.622 0.378 0.000
C67.7 Urachus
0.622 0.378 0.000
C67.5 Bladder neck
0.622 0.378 0.000
C67.3 Anterior wall of bladder
0.622 0.378 0.000
C67.1 Dome of bladder
0.622 0.378 0.000
C67.0 Trigone of bladder
0.622 0.378 0.000
G23 Other degenerative diseases of basal ganglia
0.621 0.379 0.000
G21 Secondary Parkinsonism
0.621 0.379 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.621 0.379 0.000
G22 Parkinsonism in diseases classified elsewhere
0.621 0.379 0.000
M23.9 Internal derangement of knee, unspecified
0.620 0.379 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.620 0.379 0.000
M23.5 Chronic instability of knee
0.620 0.379 0.000
M23.1 Discoid meniscus (congenital)
0.620 0.379 0.000
M23.0 Cystic meniscus
0.620 0.379 0.000
H92 Otalgia and effusion of ear
0.620 0.380 0.000
M23.8 Other internal derangements of knee
0.620 0.380 0.000
H57 Other disorders of eye and adnexa
0.619 0.381 0.000
H20 Iridocyclitis
0.619 0.381 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.619 0.381 0.000
T40.2 Other opioids
0.619 0.381 0.000
K85.9 Acute pancreatitis, unspecified
0.618 0.382 0.000
C83.3 Large cell (diffuse)
0.618 0.382 0.000
K85.1 Biliary acute pancreatitis
0.618 0.382 0.000
M35 Other systemic involvement of connective tissue
0.618 0.382 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.618 0.382 0.000
S00-S09 Injuries to the head
0.617 0.383 0.000
G83 Other paralytic syndromes
0.617 0.383 0.000
K86.3 Pseudocyst of pancreas
0.616 0.384 0.000
H91.8 Other specified hearing loss
0.616 0.384 0.000
H91.3 Deaf mutism, not elsewhere classified
0.616 0.384 0.000
H91.2 Sudden idiopathic hearing loss
0.616 0.384 0.000
H91.1 Presbycusis
0.616 0.384 0.000
H91.0 Ototoxic hearing loss
0.616 0.384 0.000
H49 Paralytic strabismus
0.615 0.385 0.000
K13.0 Diseases of lips
0.614 0.386 0.000
S20 Superficial injury of thorax
0.614 0.386 0.000
K12.1 Other forms of stomatitis
0.614 0.386 0.000
G36 Other acute disseminated demyelination
0.614 0.386 0.000
K05.3 Chronic periodontitis
0.613 0.387 0.000
M10 Gout
0.613 0.387 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.613 0.387 0.000
H53-H54 Visual disturbances and blindness
0.613 0.387 0.000
H18 Other disorders of cornea
0.613 0.387 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.613 0.387 0.000
G82 Paraplegia and tetraplegia
0.611 0.389 0.000
O80.0 Spontaneous vertex delivery
0.611 0.389 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.610 0.390 0.000
H90 Conductive and sensorineural hearing loss
0.610 0.390 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.610 0.390 0.000
M07 Psoriatic and enteropathic arthropathies
0.610 0.390 0.000
H35.4 Peripheral retinal degeneration
0.609 0.391 0.000
I42.9 Cardiomyopathy, unspecified
0.608 0.392 0.000
T23 Burn and corrosion of wrist and hand
0.608 0.392 0.000
I33.0 Acute and subacute infective endocarditis
0.607 0.393 0.000
I35 Nonrheumatic aortic valve disorders
0.607 0.393 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.607 0.393 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.606 0.394 0.000
C85.0 Lymphosarcoma
0.606 0.394 0.000
C51-C58 Malignant neoplasms of female genital organs
0.606 0.394 0.000
K60.0 Acute anal fissure
0.606 0.394 0.000
H43.9 Disorder of vitreous body, unspecified
0.606 0.394 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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