TreeWAS – Variant ID: rs17388568

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J45.9 Asthma, unspecified	0.992	0.008	0.000
J45 Asthma	0.975	0.025	0.000
J45.0 Predominantly allergic asthma	0.951	0.049	0.000
J40-J47 Chronic lower respiratory diseases	0.798	0.202	0.000
J46 Status asthmaticus	0.769	0.231	0.000
J42 Unspecified chronic bronchitis	0.764	0.236	0.000
J45.1 Nonallergic asthma	0.753	0.247	0.000
K51.9 Ulcerative colitis, unspecified	0.733	0.267	0.000
K51 Ulcerative colitis	0.733	0.267	0.000
K51.8 Other ulcerative colitis	0.716	0.284	0.000
J45.8 Mixed asthma	0.699	0.301	0.000
K51.2 Ulcerative (chronic) proctitis	0.694	0.306	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.683	0.317	0.000
J40 Bronchitis, not specified as acute or chronic	0.636	0.364	0.000
K51.5 Mucosal proctocolitis	0.584	0.415	0.000
J41 Simple and mucopurulent chronic bronchitis	0.572	0.428	0.000
K51.4 Pseudopolyposis of colon	0.557	0.443	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.464	0.536	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.463	0.537	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.410	0.590	0.000
J41.1 Mucopurulent chronic bronchitis	0.410	0.590	0.000
J41.0 Simple chronic bronchitis	0.410	0.590	0.000
J43 Emphysema	0.396	0.604	0.000
J47 Bronchiectasis	0.376	0.624	0.000
J43.8 Other emphysema	0.284	0.716	0.000
J43.1 Panlobular emphysema	0.284	0.716	0.000
J43.0 MacLeod's syndrome	0.284	0.716	0.000
J43.2 Centrilobular emphysema	0.255	0.745	0.000
J43.9 Emphysema, unspecified	0.168	0.832	0.000
K50-K52 Noninfective enteritis and colitis	0.134	0.866	0.000
K50 Crohn's disease [regional enteritis]	0.090	0.910	0.000
K50.9 Crohn's disease, unspecified	0.085	0.915	0.000
K90.0 Coeliac disease	0.082	0.918	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.048	0.952	0.000
K50.1 Crohn's disease of large intestine	0.048	0.952	0.000
K50.0 Crohn's disease of small intestine	0.042	0.958	0.000
K50.8 Other Crohn's disease	0.041	0.959	0.000
G25 Other extrapyramidal and movement disorders	0.037	0.963	0.000
G25.0 Essential tremor	0.035	0.965	0.000
K52 Other non-infective gastro-enteritis and colitis	0.031	0.969	0.000
S62.61 Fracture of other finger (open)	0.000	0.971	0.029
G25.3 Myoclonus	0.028	0.972	0.000
G25.5 Other chorea	0.028	0.972	0.000
G25.1 Drug-induced tremor	0.027	0.973	0.000
S62.60 Fracture of other finger (closed)	0.000	0.973	0.027
G25.6 Drug-induced tics and other tics of organic origin	0.026	0.973	0.000
G25.4 Drug-induced chorea	0.026	0.973	0.000
S62.6 Fracture of other finger	0.000	0.974	0.026
F31.9 Bipolar affective disorder, unspecified	0.026	0.974	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.025	0.975	0.000
F31 Bipolar affective disorder	0.025	0.975	0.000
G25.2 Other specified forms of tremor	0.025	0.975	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.023	0.977	0.000
K52.3 Indeterminate colitis	0.022	0.978	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.021	0.978	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.021	0.979	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.020	0.980	0.000
F31.7 Bipolar affective disorder, currently in remission	0.020	0.980	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.020	0.980	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.020	0.980	0.000
J44 Other chronic obstructive pulmonary disease	0.020	0.980	0.000
F31.8 Other bipolar affective disorders	0.019	0.981	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.019	0.981	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.018	0.982	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.016	0.984	0.000
K90 Intestinal malabsorption	0.015	0.985	0.000
F30-F39 Mood [affective] disorders	0.015	0.985	0.000
F30 Manic episode	0.013	0.987	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.000	0.987	0.013
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.013	0.987	0.000
F34 Persistent mood [affective] disorders	0.012	0.988	0.000
F33 Recurrent depressive disorder	0.012	0.988	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.012	0.988	0.000
F39 Unspecified mood [affective] disorder	0.012	0.988	0.000
F30.9 Manic episode, unspecified	0.012	0.988	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.988	0.012
M19.9 Arthrosis, unspecified	0.000	0.989	0.011
K90.3 Pancreatic steatorrhoea	0.011	0.989	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.011	0.989	0.000
K90.1 Tropical sprue	0.011	0.989	0.000
F38 Other mood [affective] disorders	0.011	0.989	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.011	0.989	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.989	0.011
F33.0 Recurrent depressive disorder, current episode mild	0.011	0.989	0.000
K90.8 Other intestinal malabsorption	0.010	0.989	0.000
F34.1 Dysthymia	0.010	0.990	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.000	0.990	0.010
F30.1 Mania without psychotic symptoms	0.010	0.990	0.000
F30.8 Other manic episodes	0.010	0.990	0.000
F30.2 Mania with psychotic symptoms	0.010	0.990	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.990	0.010
K52.1 Toxic gastro-enteritis and colitis	0.009	0.991	0.000
H00.1 Chalazion	0.009	0.991	0.000
F30.0 Hypomania	0.009	0.991	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.991	0.009
F33.8 Other recurrent depressive disorders	0.009	0.991	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.009	0.991	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.009	0.991	0.000
F34.8 Other persistent mood [affective] disorders	0.009	0.991	0.000
F34.0 Cyclothymia	0.009	0.991	0.000
C01 Malignant neoplasm of base of tongue	0.000	0.991	0.009
C02.9 Tongue, unspecified	0.000	0.991	0.009
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.991	0.009
C09 Malignant neoplasm of tonsil	0.000	0.992	0.008
C10 Malignant neoplasm of oropharynx	0.000	0.992	0.008
F38.8 Other specified mood [affective] disorders	0.008	0.992	0.000
F38.1 Other recurrent mood [affective] disorders	0.008	0.992	0.000
F38.0 Other single mood [affective] disorders	0.008	0.992	0.000
H40.0 Glaucoma suspect	0.000	0.992	0.008
C09.9 Tonsil, unspecified	0.000	0.992	0.008
C04 Malignant neoplasm of floor of mouth	0.000	0.992	0.008
M19.92 Arthrosis, unspecified (Upper arm)	0.000	0.992	0.008
C10.9 Oropharynx, unspecified	0.000	0.992	0.008
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.992	0.008
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.008	0.992	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.007	0.992	0.000
C04.9 Floor of mouth, unspecified	0.000	0.992	0.007
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.993	0.007
C02.1 Border of tongue	0.000	0.993	0.007
K90.9 Intestinal malabsorption, unspecified	0.007	0.993	0.000
C13 Malignant neoplasm of hypopharynx	0.000	0.993	0.007
C08 Malignant neoplasm of other and unspecified major salivary glands	0.000	0.993	0.007
C12 Malignant neoplasm of pyriform sinus	0.000	0.993	0.007
F33.9 Recurrent depressive disorder, unspecified	0.007	0.993	0.000
C03 Malignant neoplasm of gum	0.000	0.993	0.007
C02.8 Overlapping lesion of tongue	0.000	0.993	0.006
C02.3 Anterior two-thirds of tongue, part unspecified	0.000	0.993	0.006
C02.2 Ventral surface of tongue	0.000	0.993	0.006
C02.0 Dorsal surface of tongue	0.000	0.993	0.006
C06 Malignant neoplasm of other and unspecified parts of mouth	0.000	0.993	0.006
N70.9 Salpingitis and oophoritis, unspecified	0.006	0.994	0.000
J30.1 Allergic rhinitis due to pollen	0.006	0.994	0.000
G20-G26 Extrapyramidal and movement disorders	0.006	0.994	0.000
C11 Malignant neoplasm of nasopharynx	0.000	0.994	0.006
C05 Malignant neoplasm of palate	0.000	0.994	0.006
C09.8 Overlapping lesion of tonsil	0.000	0.994	0.006
C09.1 Tonsillar pillar (anterior) (posterior)	0.000	0.994	0.006
C09.0 Tonsillar fossa	0.000	0.994	0.006
C10.8 Overlapping lesion of oropharynx	0.000	0.994	0.006
C10.4 Branchial cleft	0.000	0.994	0.006
C10.3 Posterior wall of oropharynx	0.000	0.994	0.006
C10.2 Lateral wall of oropharynx	0.000	0.994	0.006
C10.1 Anterior surface of epiglottis	0.000	0.994	0.006
C10.0 Vallecula	0.000	0.994	0.006
C14.0 Pharynx, unspecified	0.000	0.994	0.006
C07 Malignant neoplasm of parotid gland	0.000	0.994	0.006
C04.8 Overlapping lesion of floor of mouth	0.000	0.994	0.006
C04.1 Lateral floor of mouth	0.000	0.994	0.006
C00 Malignant neoplasm of lip	0.000	0.994	0.006
H61.1 Non-infective disorders of pinna	0.006	0.994	0.000
C04.0 Anterior floor of mouth	0.000	0.994	0.006
C13.9 Hypopharynx, unspecified	0.000	0.994	0.005
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.000	0.994	0.005
C14.2 Waldeyer's ring	0.000	0.994	0.005
C08.9 Major salivary gland, unspecified	0.000	0.994	0.005
F33.1 Recurrent depressive disorder, current episode moderate	0.005	0.995	0.000
C02.4 Lingual tonsil	0.000	0.995	0.005
C13.8 Overlapping lesion of hypopharynx	0.000	0.995	0.005
C13.2 Posterior wall of hypopharynx	0.000	0.995	0.005
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.000	0.995	0.005
C13.0 Postcricoid region	0.000	0.995	0.005
C08.8 Overlapping lesion of major salivary glands	0.000	0.995	0.005
C08.1 Sublingual gland	0.000	0.995	0.005
C08.0 Submandibular gland	0.000	0.995	0.005
C03.9 Gum, unspecified	0.000	0.995	0.005
C03.1 Lower gum	0.000	0.995	0.005
C03.0 Upper gum	0.000	0.995	0.005
C06.2 Retromolar area	0.000	0.995	0.005
C06.9 Mouth, unspecified	0.000	0.995	0.005
I49.3 Ventricular premature depolarisation	0.000	0.995	0.005
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.995	0.005
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.000	0.995	0.005
C06.1 Vestibule of mouth	0.000	0.995	0.005
M19.98 Arthrosis, unspecified (Other)	0.000	0.995	0.005
C05.1 Soft palate	0.000	0.995	0.005
G21 Secondary Parkinsonism	0.005	0.995	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.005	0.995	0.000
G22 Parkinsonism in diseases classified elsewhere	0.005	0.995	0.000
C05.8 Overlapping lesion of palate	0.000	0.995	0.005
C05.2 Uvula	0.000	0.995	0.005
C05.0 Hard palate	0.000	0.995	0.005
C11.8 Overlapping lesion of nasopharynx	0.000	0.995	0.005
C11.3 Anterior wall of nasopharynx	0.000	0.995	0.005
C11.2 Lateral wall of nasopharynx	0.000	0.995	0.005
C11.1 Posterior wall of nasopharynx	0.000	0.995	0.005
C11.0 Superior wall of nasopharynx	0.000	0.995	0.005
G23 Other degenerative diseases of basal ganglia	0.005	0.995	0.000
R10.0 Acute abdomen	0.000	0.995	0.005
C00.8 Overlapping lesion of lip	0.000	0.995	0.004
C00.6 Commissure of lip	0.000	0.995	0.004
C00.5 Lip, unspecified, inner aspect	0.000	0.995	0.004
C00.4 Lower lip, inner aspect	0.000	0.995	0.004
C00.3 Upper lip, inner aspect	0.000	0.995	0.004
C00.2 External lip, unspecified	0.000	0.995	0.004
H00 Hordeolum and chalazion	0.005	0.995	0.000
C00.9 Lip, unspecified	0.000	0.996	0.004
C00.1 External lower lip	0.000	0.996	0.004
C11.9 Nasopharynx, unspecified	0.000	0.996	0.004
C00.0 External upper lip	0.000	0.996	0.004
C05.9 Palate, unspecified	0.000	0.996	0.004
Z71.9 Counselling, unspecified	0.004	0.996	0.000
C06.0 Cheek mucosa	0.000	0.996	0.004
K31.8 Other specified diseases of stomach and duodenum	0.004	0.996	0.000
G21.9 Secondary Parkinsonism, unspecified	0.004	0.996	0.000
G21.8 Other secondary Parkinsonism	0.004	0.996	0.000
G21.4 Vascular parkinsonism	0.004	0.996	0.000
G21.3 Postencephalitic Parkinsonism	0.004	0.996	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.004	0.996	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.004	0.996	0.000
G21.0 Malignant neuroleptic syndrome	0.004	0.996	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.003	0.996	0.000
G23.3 Multiple system atrophy, cerebellar type	0.003	0.996	0.000
G23.2 Striatonigral degeneration	0.003	0.996	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.003	0.996	0.000
G23.0 Hallervorden-Spatz disease	0.003	0.996	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.004	0.996	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.003	0.996	0.000
Y52.1 Calcium-channel blockers	0.004	0.996	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.004	0.996	0.000
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.003	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
N83.2 Other and unspecified ovarian cysts	0.003	0.997	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.003	0.997	0.000
G24 Dystonia	0.003	0.997	0.000
G20 Parkinson's disease	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
Y40 Systemic antibiotics	0.003	0.997	0.000
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
L03.9 Cellulitis, unspecified	0.003	0.997	0.000
H60.9 Otitis externa, unspecified	0.003	0.997	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.997	0.003
Y49.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y41.0 Sulphonamides	0.003	0.997	0.000
M19.94 Arthrosis, unspecified (Hand)	0.000	0.997	0.003
Y52.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
Y52.7 Peripheral vasodilators	0.003	0.997	0.000
M25.06 Haemarthrosis (Lower leg)	0.000	0.997	0.003
Y40.0 Penicillins	0.003	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
G24.3 Spasmodic torticollis	0.003	0.997	0.000
Y49.5 Other antipsychotics and neuroleptics	0.003	0.997	0.000
O16 Unspecified maternal hypertension	0.003	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Y41.5 Antiviral drugs	0.003	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
Y49.2 Other and unspecified antidepressants	0.003	0.997	0.000
G24.4 Idiopathic orofacial dystonia	0.002	0.997	0.000
G24.2 Idiopathic nonfamilial dystonia	0.002	0.997	0.000
G24.1 Idiopathic familial dystonia	0.002	0.997	0.000
G24.0 Drug-induced dystonia	0.002	0.997	0.000
K11.6 Mucocele of salivary gland	0.003	0.997	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.997	0.003
Y40.4 Tetracyclines	0.002	0.997	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.997	0.000
Y41.4 Anthelminthics	0.002	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.997	0.000
Z01.7 Laboratory examination	0.000	0.997	0.003
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.997	0.003
M20.4 Other hammer toe(s) (acquired)	0.000	0.997	0.003
J30 Vasomotor and allergic rhinitis	0.002	0.998	0.000
S51.8 Open wound of other parts of forearm	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
Z52.4 Kidney donor	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.998	0.002
G95.9 Disease of spinal cord, unspecified	0.000	0.998	0.002
L50.9 Urticaria, unspecified	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
N70 Salpingitis and oophoritis	0.002	0.998	0.000
G24.5 Blepharospasm	0.002	0.998	0.000
J30.4 Allergic rhinitis, unspecified	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
G24.8 Other dystonia	0.002	0.998	0.000
I84.6 Residual haemorrhoidal skin tags	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
Chapter X Diseases of the respiratory system	0.002	0.998	0.000
N87.0 Mild cervical dysplasia	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
S62 Fracture at wrist and hand level	0.000	0.998	0.002
J21.9 Acute bronchiolitis, unspecified	0.002	0.998	0.000
N13.8 Other obstructive and reflux uropathy	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.998	0.002
N50.8 Other specified disorders of male genital organs	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
R57.0 Cardiogenic shock	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.998	0.002
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
J30.2 Other seasonal allergic rhinitis	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.002	0.998	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.002	0.998	0.000
L50.0 Allergic urticaria	0.002	0.998	0.000
S00.0 Superficial injury of scalp	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.002	0.998	0.000
L52 Erythema nodosum	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Z73.8 Other problems related to life-management difficulty	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.998	0.002
Z71.7 Human immunodeficiency virus [HIV] counselling	0.002	0.998	0.000
Z71.5 Drug abuse counselling and surveillance	0.002	0.998	0.000
Z71.0 Person consulting on behalf of another person	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
C77.3 Axillary and upper limb lymph nodes	0.002	0.998	0.000
J30.0 Vasomotor rhinitis	0.002	0.998	0.000
S51.9 Open wound of forearm, part unspecified	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
J21 Acute bronchiolitis	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Z71.2 Person consulting for explanation of investigation findings	0.002	0.998	0.000
Q61 Cystic kidney disease	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Z01.6 Radiological examination, not elsewhere classified	0.000	0.998	0.002
Z03.3 Observation for suspected nervous system disorder	0.000	0.998	0.002
M50.1 Cervical disk disorder with radiculopathy	0.000	0.998	0.002
S51.0 Open wound of elbow	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.000	0.998	0.002
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
L50 Urticaria	0.002	0.998	0.000
K62.7 Radiation proctitis	0.002	0.998	0.000
Z71.3 Dietary counselling and surveillance	0.002	0.998	0.000
S51 Open wound of forearm	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
C60.9 Penis, unspecified	0.002	0.998	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
J81 Pulmonary oedema	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.002	0.998	0.000
D26.0 Cervix uteri	0.002	0.998	0.000
J32.0 Chronic maxillary sinusitis	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
N13 Obstructive and reflux uropathy	0.002	0.998	0.000
K31.1 Adult hypertrophic pyloric stenosis	0.002	0.998	0.000
N70.0 Acute salpingitis and oophoritis	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.998	0.000
Y47.4 Bromine compounds	0.001	0.998	0.000
Y47.3 Paraldehyde	0.001	0.998	0.000
Y47.2 Chloral derivatives	0.001	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
L51.9 Erythema multiforme, unspecified	0.002	0.998	0.000
N42.8 Other specified disorders of prostate	0.000	0.998	0.002
Z71.6 Tobacco abuse counselling	0.002	0.998	0.000
J20-J22 Other acute lower respiratory infections	0.002	0.998	0.000
S62.1 Fracture of other carpal bone(s)	0.000	0.998	0.002
L51 Erythema multiforme	0.002	0.998	0.000
S62.4 Multiple fractures of metacarpal bones	0.000	0.998	0.002
L51.1 Bullous erythema multiforme	0.002	0.998	0.000
O43.1 Malformation of placenta	0.000	0.998	0.002
Y48.5 Therapeutic gases	0.001	0.998	0.000
Y48.1 Parenteral anaesthetics	0.001	0.998	0.000
Y48.0 Inhaled anaesthetics	0.001	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
J21.8 Acute bronchiolitis due to other specified organisms	0.001	0.998	0.000
J21.1 Acute bronchiolitis due to human metapneumovirus	0.001	0.998	0.000
J21.0 Acute bronchiolitis due to respiratory syncytial virus	0.001	0.998	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.998	0.002
Z73 Problems related to life-management difficulty	0.002	0.998	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
I15.1 Hypertension secondary to other renal disorders	0.000	0.998	0.002
Q61.8 Other cystic kidney diseases	0.000	0.998	0.001
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.001
Y57.7 Vitamins, not elsewhere classified	0.001	0.998	0.000
Y57.4 Pharmaceutical excipients	0.001	0.998	0.000
Y57.3 Alcohol deterrents	0.001	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.001	0.998	0.000
Y57.1 Lipotropic drugs	0.001	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.001	0.998	0.000
K90-K93 Other diseases of the digestive system	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.000	0.998	0.001
T21.2 Burn of second degree of trunk	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.001	0.998	0.000
Z73.6 Limitation of activities due to disability	0.002	0.998	0.000
L50.6 Contact urticaria	0.001	0.998	0.000
L50.5 Cholinergic urticaria	0.001	0.998	0.000
L50.4 Vibratory urticaria	0.001	0.998	0.000
L50.3 Dermatographic urticaria	0.001	0.998	0.000
L50.2 Urticaria due to cold and heat	0.001	0.998	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.002	0.998	0.000
J20 Acute bronchitis	0.002	0.998	0.000
H72.8 Other perforations of tympanic membrane	0.002	0.998	0.000
J33.8 Other polyp of sinus	0.002	0.998	0.000
S62.5 Fracture of thumb	0.000	0.998	0.002
Y44.2 Anticoagulants	0.002	0.998	0.000
R57.2 Septic shock	0.002	0.998	0.000
S62.2 Fracture of first metacarpal bone	0.000	0.998	0.001
G24.9 Dystonia, unspecified	0.001	0.998	0.000
J20.8 Acute bronchitis due to other specified organisms	0.001	0.998	0.000
S62.51 Fracture of thumb (open)	0.000	0.998	0.001
F52.2 Failure of genital response	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations