TreeWAS – Variant ID: rs1740428

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.000	1.000
I25.2 Old myocardial infarction	0.000	0.004	0.996
I20-I25 Ischaemic heart diseases	0.000	0.009	0.991
I20 Angina pectoris	0.000	0.010	0.990
I20.9 Angina pectoris, unspecified	0.000	0.012	0.988
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.075	0.925
I20.1 Angina pectoris with documented spasm	0.000	0.130	0.870
I20.8 Other forms of angina pectoris	0.000	0.214	0.786
I22 Subsequent myocardial infarction	0.000	0.218	0.782
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.276	0.724
I20.0 Unstable angina	0.000	0.276	0.724
I23 Certain current complications following acute myocardial infarction	0.000	0.282	0.718
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I25.3 Aneurysm of heart	0.000	0.317	0.683
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.357	0.643
I25.4 Coronary artery aneurysm	0.000	0.391	0.609
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.410	0.589
I23.8 Other current complications following acute myocardial infarction	0.000	0.477	0.523
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.485	0.515
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.485	0.515
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.485	0.515
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.485	0.515
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.485	0.515
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.485	0.515
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.485	0.515
I25.5 Ischaemic cardiomyopathy	0.000	0.489	0.511
Chapter IX Diseases of the circulatory system	0.000	0.514	0.486
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.521	0.479
I10-I15 Hypertensive diseases	0.000	0.523	0.477
I77 Other disorders of arteries and arterioles	0.000	0.536	0.464
I71 Aortic aneurysm and dissection	0.000	0.536	0.464
I11 Hypertensive heart disease	0.000	0.542	0.458
I77.1 Stricture of artery	0.000	0.543	0.457
I10 Essential (primary) hypertension	0.000	0.544	0.456
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.548	0.452
I21 Acute myocardial infarction	0.000	0.558	0.442
I70 Atherosclerosis	0.000	0.561	0.439
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.564	0.436
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.576	0.424
I22.8 Subsequent myocardial infarction of other sites	0.000	0.578	0.422
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.604	0.396
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.616	0.384
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.623	0.377
I15 Secondary hypertension	0.000	0.626	0.374
I70.0 Atherosclerosis of aorta	0.000	0.633	0.367
I70.1 Atherosclerosis of renal artery	0.000	0.640	0.360
I21.9 Acute myocardial infarction, unspecified	0.000	0.656	0.344
I77.2 Rupture of artery	0.000	0.658	0.342
I71.0 Dissection of aorta [any part]	0.000	0.661	0.339
I70.8 Atherosclerosis of other arteries	0.000	0.664	0.336
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.664	0.336
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.664	0.336
I77.5 Necrosis of artery	0.000	0.667	0.333
I77.4 Coeliac artery compression syndrome	0.000	0.667	0.333
I77.3 Arterial fibromuscular dysplasia	0.000	0.667	0.333
I78 Diseases of capillaries	0.000	0.667	0.333
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.667	0.333
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.667	0.333
I73 Other peripheral vascular diseases	0.000	0.671	0.329
I70.9 Generalised and unspecified atherosclerosis	0.000	0.674	0.326
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.683	0.317
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.684	0.316
I00-I02 Acute rheumatic fever	0.000	0.687	0.313
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.691	0.309
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.691	0.309
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.692	0.308
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.695	0.305
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.697	0.303
I73.9 Peripheral vascular disease, unspecified	0.000	0.697	0.303
I15.9 Seconday hypertension, unspecified	0.000	0.698	0.302
I13 Hypertensive heart and renal disease	0.000	0.702	0.298
I15.1 Hypertension secondary to other renal disorders	0.000	0.704	0.296
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.706	0.293
I21.4 Acute subendocardial myocardial infarction	0.000	0.712	0.288
I77.0 Arteriovenous fistula, acquired	0.000	0.716	0.283
I77.8 Other specified disorders of arteries and arterioles	0.000	0.729	0.271
I15.0 Renovascular hypertension	0.000	0.731	0.269
I15.2 Hypertension secondary to endocrine disorders	0.000	0.731	0.268
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.734	0.266
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.735	0.265
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.737	0.263
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.738	0.262
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.742	0.258
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.746	0.254
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.750	0.250
I28 Other diseases of pulmonary vessels	0.000	0.750	0.250
I05-I09 Chronic rheumatic heart diseases	0.000	0.754	0.246
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.755	0.245
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.001	0.757	0.243
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.759	0.241
I24 Other acute ischaemic heart diseases	0.000	0.760	0.240
I78.9 Disease of capillaries, unspecified	0.000	0.761	0.239
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.766	0.234
I15.8 Other secondary hypertension	0.000	0.771	0.229
I02 Rheumatic chorea	0.000	0.775	0.224
I01 Rheumatic fever with heart involvement	0.000	0.775	0.224
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.778	0.222
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.779	0.221
I27 Other pulmonary heart diseases	0.000	0.782	0.218
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.783	0.217
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.786	0.214
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.786	0.214
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.786	0.214
I99 Other and unspecified disorders of circulatory system	0.000	0.790	0.210
I78.8 Other diseases of capillaries	0.000	0.792	0.208
I28.8 Other specified diseases of pulmonary vessels	0.000	0.793	0.207
I27.9 Pulmonary heart disease, unspecified	0.000	0.799	0.201
I73.8 Other specified peripheral vascular diseases	0.000	0.799	0.201
I07 Rheumatic tricuspid valve diseases	0.000	0.800	0.200
I00 Rheumatic fever without mention of heart involvement	0.000	0.812	0.188
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.818	0.182
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.821	0.179
I28.1 Aneurysm of pulmonary artery	0.000	0.821	0.179
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.821	0.179
I05 Rheumatic mitral valve diseases	0.000	0.821	0.179
I77.6 Arteritis, unspecified	0.000	0.822	0.178
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.001	0.823	0.176
I79.1 Aortitis in diseases classified elsewhere	0.001	0.825	0.174
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.001	0.825	0.174
I13.9 Hypertensive heart and renal disease, unspecified	0.001	0.829	0.170
I09 Other rheumatic heart diseases	0.000	0.830	0.169
I07.1 Tricuspid insufficiency	0.000	0.834	0.166
A49.8 Other bacterial infections of unspecified site	0.165	0.835	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.837	0.163
I06 Rheumatic aortic valve diseases	0.000	0.837	0.163
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.839	0.161
I01.8 Other acute rheumatic heart disease	0.000	0.839	0.161
I01.2 Acute rheumatic myocarditis	0.000	0.839	0.161
I01.1 Acute rheumatic endocarditis	0.000	0.839	0.161
I01.0 Acute rheumatic pericarditis	0.000	0.839	0.161
I02.9 Rheumatic chorea without heart involvement	0.000	0.839	0.161
I02.0 Rheumatic chorea with heart involvement	0.000	0.839	0.161
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.841	0.159
I27.1 Kyphoscoliotic heart disease	0.000	0.844	0.156
I30-I52 Other forms of heart disease	0.000	0.850	0.150
I45 Other conduction disorders	0.000	0.850	0.150
I74 Arterial embolism and thrombosis	0.000	0.850	0.150
A49.0 Staphylococcal infection, unspecified	0.149	0.851	0.000
A49 Bacterial infection of unspecified site	0.149	0.851	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.851	0.149
I45.6 Preexcitation syndrome	0.000	0.852	0.148
I72 Other aneurysm	0.001	0.853	0.146
I24.8 Other forms of acute ischaemic heart disease	0.000	0.853	0.147
I05.0 Mitral stenosis	0.000	0.855	0.145
I05.2 Mitral stenosis with insufficiency	0.000	0.856	0.144
I07.9 Tricuspid valve disease, unspecified	0.000	0.857	0.143
I07.8 Other tricuspid valve diseases	0.000	0.857	0.143
I07.2 Tricuspid stenosis with insufficiency	0.000	0.857	0.143
I07.0 Tricuspid stenosis	0.000	0.857	0.143
I31 Other diseases of pericardium	0.000	0.859	0.141
I46 Cardiac arrest	0.000	0.859	0.141
I97.1 Other functional disturbances following cardiac surgery	0.000	0.860	0.139
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.861	0.139
I31.9 Disease of pericardium, unspecified	0.000	0.862	0.138
I46.0 Cardiac arrest with successful resuscitation	0.000	0.863	0.137
I72.4 Aneurysm of artery of lower extremity	0.000	0.863	0.137
I12 Hypertensive renal disease	0.000	0.866	0.134
I05.1 Rheumatic mitral insufficiency	0.000	0.867	0.133
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.868	0.132
I35 Nonrheumatic aortic valve disorders	0.000	0.868	0.132
E78.0 Pure hypercholesterolaemia	0.000	0.868	0.132
I95 Hypotension	0.000	0.869	0.131
I26 Pulmonary embolism	0.000	0.870	0.130
I30 Acute pericarditis	0.000	0.871	0.129
I45.9 Conduction disorder, unspecified	0.000	0.871	0.129
I97.0 Postcardiotomy syndrome	0.000	0.872	0.128
I06.1 Rheumatic aortic insufficiency	0.000	0.873	0.127
A49.1 Streptococcal infection, unspecified	0.126	0.874	0.000
I24.1 Dressler's syndrome	0.000	0.874	0.125
I45.5 Other specified heart block	0.000	0.877	0.123
I95.0 Idiopathic hypotension	0.000	0.878	0.122
I35.1 Aortic (valve) insufficiency	0.000	0.878	0.122
I09.8 Other specified rheumatic heart diseases	0.000	0.878	0.122
I09.2 Chronic rheumatic pericarditis	0.000	0.878	0.122
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.878	0.122
I09.0 Rheumatic myocarditis	0.000	0.878	0.122
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.878	0.122
I05.8 Other mitral valve diseases	0.000	0.879	0.121
I45.1 Other and unspecified right bundle-branch block	0.000	0.879	0.121
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.000	0.880	0.120
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.881	0.119
I31.1 Chronic constrictive pericarditis	0.000	0.882	0.117
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.883	0.117
I06.8 Other rheumatic aortic valve diseases	0.000	0.883	0.117
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.883	0.117
I35.0 Aortic (valve) stenosis	0.000	0.883	0.117
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.884	0.115
I09.9 Rheumatic heart disease, unspecified	0.000	0.885	0.115
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.886	0.114
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.886	0.114
I98.0 Cardiovascular syphilis	0.000	0.886	0.114
I40 Acute myocarditis	0.000	0.886	0.114
I30.9 Acute pericarditis, unspecified	0.000	0.887	0.113
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.889	0.111
I45.4 Nonspecific intraventricular block	0.000	0.891	0.109
I27.8 Other specified pulmonary heart diseases	0.000	0.891	0.109
I52 Other heart disorders in diseases classified elsewhere	0.000	0.892	0.108
I48 Atrial fibrillation and flutter	0.000	0.892	0.108
I41 Myocarditis in diseases classified elsewhere	0.000	0.892	0.108
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.892	0.108
I32 Pericarditis in diseases classified elsewhere	0.000	0.892	0.108
I45.0 Right fascicular block	0.000	0.892	0.107
A49.3 Mycoplasma infection, unspecified	0.107	0.893	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.893	0.107
I36 Nonrheumatic tricuspid valve disorders	0.000	0.894	0.106
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.894	0.106
I72.6 Aneurysm and dissection of vertebral artery	0.001	0.894	0.105
I72.5 Aneurysm and dissection of other precerebral arteries	0.001	0.894	0.105
I30.1 Infective pericarditis	0.000	0.896	0.104
I35.9 Aortic valve disorder, unspecified	0.000	0.896	0.104
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.896	0.104
I73.0 Raynaud's syndrome	0.000	0.897	0.103
I45.2 Bifascicular block	0.000	0.897	0.103
I31.8 Other specified diseases of pericardium	0.000	0.899	0.101
I31.2 Haemopericardium, not elsewhere classified	0.000	0.899	0.101
Z82.2 Family history of deafness and hearing loss	0.000	0.899	0.101
I46.1 Sudden cardiac death, so described	0.000	0.899	0.101
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.900	0.100
I37 Pulmonary valve disorders	0.000	0.902	0.098
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.903	0.097
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.904	0.096
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.905	0.095
I74.8 Embolism and thrombosis of other arteries	0.000	0.905	0.095
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.906	0.094
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.907	0.092
E78.2 Mixed hyperlipidaemia	0.000	0.908	0.092
I72.2 Aneurysm of renal artery	0.001	0.909	0.090
I40.9 Acute myocarditis, unspecified	0.000	0.911	0.089
A49.2 Haemophilus influenzae infection, unspecified	0.089	0.911	0.000
I06.0 Rheumatic aortic stenosis	0.000	0.913	0.086
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.000	0.913	0.086
I72.9 Aneurysm of unspecified site	0.001	0.915	0.084
I72.1 Aneurysm of artery of upper extremity	0.001	0.915	0.083
I45.3 Trifascicular block	0.000	0.915	0.084
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.916	0.083
E78.5 Hyperlipidaemia, unspecified	0.000	0.916	0.084
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.918	0.082
I40.8 Other acute myocarditis	0.000	0.918	0.082
I40.1 Isolated myocarditis	0.000	0.918	0.082
I95.8 Other hypotension	0.000	0.919	0.081
Z82.1 Family history of blindness and visual loss	0.000	0.920	0.080
I40.0 Infective myocarditis	0.000	0.920	0.079
I46.9 Cardiac arrest, unspecified	0.000	0.921	0.079
I05.9 Mitral valve disease, unspecified	0.000	0.921	0.079
I31.0 Chronic adhesive pericarditis	0.000	0.921	0.079
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.922	0.078
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.922	0.078
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.922	0.078
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.922	0.078
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.922	0.078
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.922	0.078
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.922	0.078
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.922	0.078
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.922	0.078
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.922	0.078
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.922	0.078
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.922	0.078
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.922	0.078
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.922	0.078
I48.4 Atypical atrial flutter	0.000	0.922	0.078
I48.3 Typical atrial flutter	0.000	0.922	0.078
I48.2 Chronic atrial fibrillation	0.000	0.922	0.078
I48.1 Persistent atrial fibrillation	0.000	0.922	0.078
I48.0 Paroxysmal atrial fibrillation	0.000	0.922	0.078
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.922	0.078
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.922	0.078
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.922	0.078
I72.0 Aneurysm of carotid artery	0.001	0.923	0.076
I74.5 Embolism and thrombosis of iliac artery	0.000	0.924	0.076
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.924	0.076
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.924	0.076
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.924	0.076
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.924	0.076
I30.8 Other forms of acute pericarditis	0.000	0.924	0.076
I45.8 Other specified conduction disorders	0.000	0.925	0.075
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.925	0.075
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.925	0.074
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.925	0.074
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.925	0.074
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.000	0.926	0.074
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.926	0.074
I31.3 Pericardial effusion (noninflammatory)	0.000	0.926	0.074
Z95.1 Presence of aortocoronary bypass graft	0.000	0.927	0.073
I95.9 Hypotension, unspecified	0.000	0.928	0.072
I35.8 Other aortic valve disorders	0.000	0.929	0.071
I72.3 Aneurysm of iliac artery	0.001	0.929	0.070
I37.9 Pulmonary valve disorder, unspecified	0.000	0.930	0.070
I37.8 Other pulmonary valve disorders	0.000	0.930	0.070
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.930	0.070
I37.0 Pulmonary valve stenosis	0.000	0.930	0.070
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.930	0.070
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.002	0.930	0.069
E78.1 Pure hyperglyceridaemia	0.000	0.931	0.069
E78.3 Hyperchylomicronaemia	0.000	0.932	0.068
I78.1 Naevus, nonneoplastic	0.000	0.932	0.067
I33 Acute and subacute endocarditis	0.000	0.933	0.067
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.934	0.066
I95.2 Hypotension due to drugs	0.000	0.934	0.066
I27.0 Primary pulmonary hypertension	0.000	0.936	0.064
E78.4 Other hyperlipidaemia	0.000	0.938	0.062
E78.8 Other disorders of lipoprotein metabolism	0.000	0.940	0.060
I37.1 Pulmonary valve insufficiency	0.000	0.940	0.060
A49.9 Bacterial infection, unspecified	0.059	0.941	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.943	0.057
E78.6 Lipoprotein deficiency	0.000	0.944	0.056
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.944	0.056
I44 Atrioventricular and left bundle-branch block	0.000	0.945	0.055
I51 Complications and ill-defined descriptions of heart disease	0.000	0.945	0.055
I44.7 Left bundle-branch block, unspecified	0.000	0.945	0.055
I51.6 Cardiovascular disease, unspecified	0.000	0.949	0.051
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.952	0.048
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.954	0.046
I33.9 Acute endocarditis, unspecified	0.000	0.954	0.046
I12.9 Hypertensive renal disease without renal failure	0.000	0.954	0.045
I08 Multiple valve diseases	0.000	0.957	0.043
I47 Paroxysmal tachycardia	0.000	0.957	0.043
I51.0 Cardiac septal defect, acquired	0.000	0.958	0.042
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.959	0.041
I51.4 Myocarditis, unspecified	0.000	0.960	0.040
I44.4 Left anterior fascicular block	0.000	0.960	0.040
I44.5 Left posterior fascicular block	0.000	0.960	0.040
I51.5 Myocardial degeneration	0.000	0.961	0.039
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.961	0.039
A30-A49 Other bacterial diseases	0.039	0.961	0.000
I72.8 Aneurysm of other specified arteries	0.002	0.962	0.036
I44.6 Other and unspecified fascicular block	0.000	0.962	0.038
I38 Endocarditis, valve unspecified	0.000	0.963	0.037
I34 Nonrheumatic mitral valve disorders	0.000	0.964	0.036
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.965	0.035
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.965	0.035
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.966	0.034
I95.1 Orthostatic hypotension	0.000	0.967	0.033
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.967	0.033
I42 Cardiomyopathy	0.000	0.968	0.032
I47.0 Reentry ventricular arrhythmia	0.000	0.968	0.032
Z95.0 Presence of cardiac pacemaker	0.000	0.969	0.031
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.970	0.030
A39 Meningococcal infection	0.030	0.970	0.000
A46 Erysipelas	0.030	0.970	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.971	0.029
A40 Streptococcal septicaemia	0.029	0.971	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.971	0.029
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.971	0.029
I08.9 Multiple valve disease, unspecified	0.000	0.971	0.029
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.972	0.028
A44 Bartonellosis	0.028	0.972	0.000
A43 Nocardiosis	0.028	0.972	0.000
A42 Actinomycosis	0.028	0.972	0.000
A37 Whooping cough	0.028	0.972	0.000
A36 Diphtheria	0.028	0.972	0.000
A32 Listeriosis	0.028	0.972	0.000
A30 Leprosy [Hansen's disease]	0.028	0.972	0.000
A38 Scarlet fever	0.028	0.972	0.000
A35 Other tetanus	0.028	0.972	0.000
A34 Obstetrical tetanus	0.028	0.972	0.000
A33 Tetanus neonatorum	0.028	0.972	0.000
I47.2 Ventricular tachycardia	0.000	0.972	0.028
A48 Other bacterial diseases, not elsewhere classified	0.027	0.972	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.973	0.027
I08.8 Other multiple valve diseases	0.000	0.973	0.027
I42.2 Other hypertrophic cardiomyopathy	0.000	0.973	0.027
A40.9 Streptococcal septicaemia, unspecified	0.027	0.973	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.973	0.026
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.974	0.026
A39.4 Meningococcaemia, unspecified	0.025	0.975	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.975	0.025
I51.8 Other ill-defined heart diseases	0.000	0.975	0.025
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.975	0.025
Z82.3 Family history of stroke	0.000	0.975	0.025
I42.6 Alcoholic cardiomyopathy	0.000	0.976	0.024
I08.0 Disorders of both mitral and aortic valves	0.000	0.976	0.024
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.977	0.023
A40.8 Other streptococcal septicaemia	0.022	0.977	0.000
I44.0 Atrioventricular block, first degree	0.000	0.978	0.022
A39.9 Meningococcal infection, unspecified	0.022	0.978	0.000
A39.8 Other meningococcal infections	0.022	0.978	0.000
A39.5 Meningococcal heart disease	0.022	0.978	0.000
A39.3 Chronic meningococcaemia	0.022	0.978	0.000
A39.2 Acute meningococcaemia	0.022	0.978	0.000
A39.1 Waterhouse-Friderichsen syndrome	0.022	0.978	0.000
A40.2 Septicaemia due to streptococcus, group D	0.021	0.979	0.000
A48.1 Legionnaires' disease	0.021	0.979	0.000
I42.5 Other restrictive cardiomyopathy	0.000	0.979	0.021
I49 Other cardiac arrhythmias	0.000	0.979	0.021
A31 Infection due to other mycobacteria	0.021	0.979	0.000
A30.9 Leprosy, unspecified	0.020	0.980	0.000
A30.8 Other forms of leprosy	0.020	0.980	0.000
A30.5 Lepromatous leprosy	0.020	0.980	0.000
A30.4 Borderline lepromatous leprosy	0.020	0.980	0.000
A30.3 Borderline leprosy	0.020	0.980	0.000
A30.2 Borderline tuberculoid leprosy	0.020	0.980	0.000
A30.1 Tuberculoid leprosy	0.020	0.980	0.000
A30.0 Indeterminate leprosy	0.020	0.980	0.000
A32.9 Listeriosis, unspecified	0.020	0.980	0.000
A32.8 Other forms of listeriosis	0.020	0.980	0.000
A32.7 Listerial septicaemia	0.020	0.980	0.000
A32.1 Listerial meningitis and meningoencephalitis	0.020	0.980	0.000
A32.0 Cutaneous listeriosis	0.020	0.980	0.000
A36.9 Diphtheria, unspecified	0.020	0.980	0.000
A36.8 Other diphtheria	0.020	0.980	0.000
A36.3 Cutaneous diphtheria	0.020	0.980	0.000
A36.2 Laryngeal diphtheria	0.020	0.980	0.000
A36.1 Nasopharyngeal diphtheria	0.020	0.980	0.000
A36.0 Pharyngeal diphtheria	0.020	0.980	0.000
A37.9 Whooping cough, unspecified	0.020	0.980	0.000
A37.8 Whooping cough due to other Bordetella species	0.020	0.980	0.000
A37.1 Whooping cough due to Bordetella parapertussis	0.020	0.980	0.000
A37.0 Whooping cough due to Bordetella pertussis	0.020	0.980	0.000
A42.9 Actinomycosis, unspecified	0.020	0.980	0.000
A42.8 Other forms of actinomycosis	0.020	0.980	0.000
A42.7 Actinomycotic septicaemia	0.020	0.980	0.000
A42.2 Cervicofacial actinomycosis	0.020	0.980	0.000
A42.1 Abdominal actinomycosis	0.020	0.980	0.000
A42.0 Pulmonary actinomycosis	0.020	0.980	0.000
A43.9 Nocardiosis, unspecified	0.020	0.980	0.000
A43.8 Other forms of nocardiosis	0.020	0.980	0.000
A43.1 Cutaneous nocardiosis	0.020	0.980	0.000
A43.0 Pulmonary nocardiosis	0.020	0.980	0.000
A44.9 Bartonellosis, unspecified	0.020	0.980	0.000
A44.8 Other forms of bartonellosis	0.020	0.980	0.000
A44.1 Cutaneous and mucocutaneous bartonellosis	0.020	0.980	0.000
A44.0 Systemic bartonellosis	0.020	0.980	0.000
A40.0 Septicaemia due to streptococcus, group A	0.020	0.980	0.000
A48.4 Brazilian purpuric fever	0.020	0.980	0.000
A48.3 Toxic shock syndrome	0.020	0.980	0.000
A48.2 Nonpneumonic Legionnaires' disease [Pontiac fever]	0.020	0.980	0.000
A48.0 Gas gangrene	0.020	0.980	0.000
A39.0 Meningococcal meningitis	0.020	0.980	0.000
I42.4 Endocardial fibroelastosis	0.000	0.980	0.020
I42.9 Cardiomyopathy, unspecified	0.000	0.980	0.020
A40.1 Septicaemia due to streptococcus, group B	0.019	0.981	0.000
I51.9 Heart disease, unspecified	0.000	0.981	0.019
I44.3 Other and unspecified atrioventricular block	0.000	0.982	0.018
I49.3 Ventricular premature depolarisation	0.000	0.982	0.018
A48.8 Other specified bacterial diseases	0.018	0.982	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.982	0.017
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.983	0.017
I49.4 Other and unspecified premature depolarisation	0.000	0.983	0.017
I50 Heart failure	0.000	0.984	0.016
M25.76 Osteophyte (Lower leg)	0.000	0.984	0.016
M79.79 Fibromyalgia (Site unspecified)	0.000	0.984	0.016
I49.2 Junctional premature depolarisation	0.000	0.985	0.015
A31.8 Other mycobacterial infections	0.015	0.985	0.000
A31.1 Cutaneous mycobacterial infection	0.015	0.985	0.000
I44.1 Atrioventricular block, second degree	0.000	0.985	0.015
I44.2 Atrioventricular block, complete	0.000	0.985	0.015
I33.0 Acute and subacute infective endocarditis	0.001	0.985	0.014
I42.8 Other cardiomyopathies	0.000	0.985	0.015
A40.3 Septicaemia due to Streptococcus pneumoniae	0.014	0.986	0.000
H18.5 Hereditary corneal dystrophies	0.014	0.986	0.000
M25.72 Osteophyte (Upper arm)	0.000	0.987	0.013
A41 Other septicaemia	0.013	0.987	0.000
M25.7 Osteophyte	0.000	0.987	0.013
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.987	0.013
I47.1 Supraventricular tachycardia	0.000	0.987	0.013
A31.0 Pulmonary mycobacterial infection	0.012	0.988	0.000
I49.1 Atrial premature depolarisation	0.000	0.988	0.012
H18 Other disorders of cornea	0.012	0.988	0.000
A31.9 Mycobacterial infection, unspecified	0.012	0.988	0.001
Z29.1 Prophylactic immunotherapy	0.000	0.988	0.012
M25.77 Osteophyte (Ankle and foot)	0.000	0.988	0.012
A41.0 Septicaemia due to Staphylococcus aureus	0.012	0.988	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.989	0.011
A41.3 Septicaemia due to Haemophilus influenzae	0.011	0.989	0.000
M25.79 Osteophyte (Site unspecified)	0.000	0.989	0.011
H18.4 Corneal degeneration	0.011	0.989	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.989	0.011
Z29.8 Other specified prophylactic measures	0.000	0.989	0.011
E27 Other disorders of adrenal gland	0.000	0.989	0.011
M25.78 Osteophyte (Other)	0.000	0.990	0.010
H18.0 Corneal pigmentations and deposits	0.010	0.990	0.000
Z29.2 Other prophylactic chemotherapy	0.000	0.990	0.010
Z29 Need for other prophylactic measures	0.000	0.990	0.010
H18.3 Changes in corneal membranes	0.010	0.990	0.000
H18.2 Other corneal oedema	0.010	0.990	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.990	0.010
H18.9 Disorder of cornea, unspecified	0.010	0.990	0.000
A41.4 Septicaemia due to anaerobes	0.010	0.990	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.990	0.010
M25.73 Osteophyte (Forearm)	0.000	0.990	0.010
E27.2 Addisonian crisis	0.000	0.990	0.010
A41.5 Septicaemia due to other Gram-negative organisms	0.010	0.990	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.990	0.010
M25.74 Osteophyte (Hand)	0.000	0.990	0.010
M25.70 Osteophyte (Multiple sites)	0.000	0.990	0.010
I42.0 Dilated cardiomyopathy	0.000	0.990	0.010
H18.1 Bullous keratopathy	0.009	0.991	0.000
M79.7 Fibromyalgia	0.000	0.991	0.009
H18.7 Other corneal deformities	0.009	0.991	0.000
H18.6 Keratoconus	0.009	0.991	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.991	0.009
A41.2 Septicaemia due to unspecified staphylococcus	0.008	0.992	0.000
H18.8 Other specified disorders of cornea	0.008	0.992	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.992	0.008
I49.8 Other specified cardiac arrhythmias	0.000	0.992	0.008
M79.70 Fibromyalgia (Multiple sites)	0.000	0.992	0.008
E27.5 Adrenomedullary hyperfunction	0.000	0.992	0.008
E27.0 Other adrenocortical overactivity	0.000	0.992	0.008

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations