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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17423649
log Bayes Factor = 70.8807
Chromosome 6   position 32,357,133  (GRCh37) Explore rs17423649 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
C44.7 Skin of lower limb, including hip
0.999 0.001 0.000
K50-K52 Noninfective enteritis and colitis
0.999 0.001 0.000
K50.1 Crohn's disease of large intestine
0.999 0.001 0.000
K50 Crohn's disease [regional enteritis]
0.999 0.001 0.000
Z93.2 Ileostomy status
0.996 0.004 0.000
K51.4 Pseudopolyposis of colon
0.993 0.007 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.990 0.010 0.000
E10.1 With ketoacidosis
0.000 0.012 0.988
C44.4 Skin of scalp and neck
0.988 0.012 0.000
C44.2 Skin of ear and external auricular canal
0.987 0.013 0.000
E10.3 With ophthalmic complications
0.000 0.014 0.986
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.984 0.016 0.000
C44.5 Skin of trunk
0.974 0.026 0.000
C44.6 Skin of upper limb, including shoulder
0.971 0.029 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.958 0.042 0.000
K51.8 Other ulcerative colitis
0.958 0.042 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.949 0.051 0.000
K51.2 Ulcerative (chronic) proctitis
0.947 0.053 0.000
C83.3 Large cell (diffuse)
0.946 0.054 0.000
C44.0 Skin of lip
0.939 0.061 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.931 0.069 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.076 0.924
D86 Sarcoidosis
0.000 0.082 0.917
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.914 0.086 0.000
D86.0 Sarcoidosis of lung
0.000 0.090 0.910
C82.0 Small cleaved cell, follicular
0.895 0.105 0.000
K50.9 Crohn's disease, unspecified
0.891 0.109 0.000
K52 Other non-infective gastro-enteritis and colitis
0.856 0.144 0.000
E10.8 With unspecified complications
0.000 0.165 0.835
K51.5 Mucosal proctocolitis
0.831 0.169 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.814 0.186 0.000
E10-E14 Diabetes mellitus
0.000 0.188 0.812
C82.3 Follicular lymphoma grade IIIa
0.797 0.203 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.784 0.216 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.229 0.771
C44.1 Skin of eyelid, including canthus
0.770 0.230 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.230 0.770
E10.0 With coma
0.000 0.233 0.766
D50-D53 Nutritional anaemias
0.000 0.236 0.764
K52.1 Toxic gastro-enteritis and colitis
0.762 0.238 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.243 0.757
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.245 0.755
E16 Other disorders of pancreatic internal secretion
0.000 0.245 0.755
E16.2 Hypoglycaemia, unspecified
0.000 0.246 0.754
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.246 0.754
K90 Intestinal malabsorption
0.000 0.251 0.749
E10.6 With other specified complications
0.000 0.253 0.747
E10.4 With neurological complications
0.000 0.253 0.747
K52.8 Other specified non-infective gastro-enteritis and colitis
0.735 0.265 0.000
C83.1 Small cleaved cell (diffuse)
0.735 0.265 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.266 0.734
E20-E35 Disorders of other endocrine glands
0.000 0.275 0.725
K51.3 Ulcerative (chronic) rectosigmoiditis
0.724 0.276 0.000
K52.3 Indeterminate colitis
0.723 0.277 0.000
K50.8 Other Crohn's disease
0.723 0.277 0.000
D50 Iron deficiency anaemia
0.000 0.278 0.722
C85.1 B-cell lymphoma, unspecified
0.721 0.279 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.283 0.717
E27 Other disorders of adrenal gland
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
D50.9 Iron deficiency anaemia, unspecified
0.000 0.283 0.717
K51.0 Ulcerative (chronic) enterocolitis
0.715 0.285 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.287 0.713
C82.6 Cutaneous follicle centre lymphoma
0.706 0.294 0.000
C82.5 Diffuse follicle centre lymphoma
0.706 0.294 0.000
C82.4 Follicular lymphoma grade IIIb
0.706 0.294 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.698 0.302 0.000
E10.2 With renal complications
0.000 0.311 0.689
C81 Hodgkin's disease
0.688 0.312 0.000
C82.2 Large cell, follicular
0.687 0.313 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.687 0.313 0.000
C94 Other leukaemias of specified cell type
0.687 0.313 0.000
C93 Monocytic leukaemia
0.687 0.313 0.000
C86 Other specified types of T/NK-cell lymphoma
0.687 0.313 0.000
C83.6 Undifferentiated (diffuse)
0.680 0.320 0.000
C83.5 Lymphoblastic (diffuse)
0.680 0.320 0.000
C83.4 Immunoblastic (diffuse)
0.680 0.320 0.000
C83.2 Mixed small and large cell (diffuse)
0.680 0.320 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.675 0.325 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.668 0.332 0.000
C85.0 Lymphosarcoma
0.668 0.332 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.338 0.662
E22 Hyperfunction of pituitary gland
0.000 0.339 0.661
C83.7 Burkitt's tumour
0.660 0.340 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.342 0.658
D86.3 Sarcoidosis of skin
0.000 0.342 0.658
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.342 0.658
D86.1 Sarcoidosis of lymph nodes
0.000 0.342 0.658
C43-C44 Melanoma and other malignant neoplasms of skin
0.656 0.344 0.000
M06.9 Rheumatoid arthritis, unspecified
0.648 0.352 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.647 0.353 0.000
M06 Other rheumatoid arthritis
0.643 0.357 0.000
M06.0 Seronegative rheumatoid arthritis
0.641 0.359 0.000
E13 Other specified diabetes mellitus
0.000 0.365 0.635
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.633 0.367 0.000
C95 Leukaemia of unspecified cell type
0.633 0.367 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.631 0.369 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.624 0.376 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.624 0.376 0.000
E10.5 With peripheral circulatory complications
0.000 0.379 0.621
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.621 0.379 0.000
C88 Malignant immunoproliferative diseases
0.608 0.392 0.000
E16.1 Other hypoglycaemia
0.000 0.396 0.604
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.396 0.604
K90.9 Intestinal malabsorption, unspecified
0.000 0.405 0.595
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.407 0.593
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.592 0.408 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.586 0.414 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.418 0.582
C85.7 Other specified types of non-Hodgkin's lymphoma
0.580 0.420 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.422 0.578
D52 Folate deficiency anaemia
0.000 0.422 0.578
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.423 0.577
K90.8 Other intestinal malabsorption
0.000 0.437 0.562
E27.2 Addisonian crisis
0.000 0.441 0.559
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.557 0.443 0.000
E24 Cushing's syndrome
0.000 0.444 0.556
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.447 0.553
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.447 0.553
D51.2 Transcobalamin II deficiency
0.000 0.447 0.553
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.447 0.553
D82 Immunodeficiency associated with other major defects
0.000 0.457 0.543
D81 Combined immunodeficiencies
0.000 0.457 0.543
C90 Multiple myeloma and malignant plasma cell neoplasms
0.543 0.457 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.543 0.457 0.000
E14 Unspecified diabetes mellitus
0.000 0.458 0.542
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.459 0.541
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.459 0.541
E16.4 Abnormal secretion of gastrin
0.000 0.459 0.541
E16.3 Increased secretion of glucagon
0.000 0.459 0.541
E15 Nondiabetic hypoglycaemic coma
0.000 0.459 0.541
K90.3 Pancreatic steatorrhoea
0.000 0.463 0.537
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.463 0.537
K90.1 Tropical sprue
0.000 0.463 0.537
C81.1 Nodular sclerosis
0.536 0.464 0.000
C81.2 Mixed cellularity
0.527 0.473 0.000
D53 Other nutritional anaemias
0.000 0.475 0.524
C81.0 Lymphocytic predominance
0.522 0.477 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.480 0.520
E32 Diseases of thymus
0.000 0.480 0.520
E31 Polyglandular dysfunction
0.000 0.480 0.520
E30 Disorders of puberty, not elsewhere classified
0.000 0.480 0.520
E25 Adrenogenital disorders
0.000 0.480 0.520
D50.1 Sideropenic dysphagia
0.000 0.482 0.518
D55-D59 Haemolytic anaemias
0.000 0.482 0.517
E27.5 Adrenomedullary hyperfunction
0.000 0.486 0.514
E27.0 Other adrenocortical overactivity
0.000 0.486 0.514
E20 Hypoparathyroidism
0.000 0.486 0.514
E21.0 Primary hyperparathyroidism
0.000 0.487 0.513
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.512 0.488 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.488 0.512
E22.0 Acromegaly and pituitary gigantism
0.000 0.490 0.510
E13.9 Without complications
0.000 0.492 0.508
E34 Other endocrine disorders
0.000 0.496 0.504
E40-E46 Malnutrition
0.000 0.500 0.499
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.498 0.502 0.000
C81.7 Other Hodgkin's disease
0.493 0.506 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.493 0.506 0.000
C81.3 Lymphocytic depletion
0.493 0.506 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.492 0.507 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.492 0.507 0.000
C86.4 Blastic NK-cell lymphoma
0.492 0.507 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.492 0.507 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.492 0.507 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.492 0.507 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.492 0.507 0.000
C93.9 Monocytic leukaemia, unspecified
0.492 0.507 0.000
C93.7 Other monocytic leukaemia
0.492 0.507 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.492 0.507 0.000
C93.2 Subacute monocytic leukaemia
0.492 0.507 0.000
C93.1 Chronic monocytic leukaemia
0.492 0.507 0.000
C93.0 Acute monocytic leukaemia
0.492 0.507 0.000
C94.7 Other specified leukaemias
0.492 0.507 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.492 0.507 0.000
C94.5 Acute myelofibrosis
0.492 0.507 0.000
C94.4 Acute panmyelosis
0.492 0.507 0.000
C94.3 Mast cell leukaemia
0.492 0.507 0.000
C94.2 Acute megakaryoblastic leukaemia
0.492 0.507 0.000
C94.1 Chronic erythraemia
0.492 0.507 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.492 0.507 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.492 0.507 0.000
C96.8 Histiocytic sarcoma
0.492 0.507 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.492 0.507 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.492 0.507 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.492 0.507 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.492 0.507 0.000
C96.3 True histiocytic lymphoma
0.492 0.507 0.000
C96.2 Malignant mast cell tumour
0.492 0.507 0.000
C96.1 Malignant histiocytosis
0.492 0.507 0.000
C96.0 Letterer-Siwe disease
0.492 0.507 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.486 0.514 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.515 0.485
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.485 0.515 0.000
M05-M14 Inflammatory polyarthropathies
0.480 0.520 0.000
E22.1 Hyperprolactinaemia
0.000 0.522 0.478
C91 Lymphoid leukaemia
0.475 0.524 0.001
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.526 0.474
E22.8 Other hyperfunction of pituitary gland
0.000 0.526 0.474
D83 Common variable immunodeficiency
0.000 0.527 0.473
E65-E68 Obesity and other hyperalimentation
0.000 0.538 0.462
M06.8 Other specified rheumatoid arthritis
0.461 0.539 0.000
M06.2 Rheumatoid bursitis
0.461 0.539 0.000
M06.1 Adult-onset Still's disease
0.461 0.539 0.000
Chapter II Neoplasms
0.460 0.540 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.459 0.541 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.459 0.541 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.459 0.541 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.459 0.541 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.459 0.541 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.459 0.541 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.459 0.541 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.458 0.542 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.457 0.543 0.000
E13.8 With unspecified complications
0.000 0.545 0.455
E13.7 With multiple complications
0.000 0.545 0.455
E13.6 With other specified complications
0.000 0.545 0.455
E13.5 With peripheral circulatory complications
0.000 0.545 0.455
E13.4 With neurological complications
0.000 0.545 0.455
E13.3 With ophthalmic complications
0.000 0.545 0.455
E13.2 With renal complications
0.000 0.545 0.455
E13.1 With ketoacidosis
0.000 0.545 0.455
E13.0 With coma
0.000 0.545 0.455
C73 Malignant neoplasm of thyroid gland
0.454 0.546 0.000
M06.3 Rheumatoid nodule
0.454 0.546 0.000
D80 Immunodeficiency with predominantly antibody defects
0.000 0.546 0.454
C95.7 Other leukaemia of unspecified cell type
0.454 0.546 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.454 0.546 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.454 0.546 0.000
C95.0 Acute leukaemia of unspecified cell type
0.454 0.546 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.549 0.451
C84.9 Mature T/NK-cell lymphoma, unspecified
0.447 0.553 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.447 0.553 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.447 0.553 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.447 0.553 0.000
C84.3 Lymphoepithelioid lymphoma
0.447 0.553 0.000
C84.2 T-zone lymphoma
0.447 0.553 0.000
C84.1 Sezary's diease
0.447 0.553 0.000
C84.0 Mycosis fungoides
0.445 0.555 0.000
M07 Psoriatic and enteropathic arthropathies
0.444 0.556 0.000
D84 Other immunodeficiencies
0.001 0.556 0.444
D52.9 Folate deficiency anaemia, unspecified
0.000 0.556 0.444
D59 Acquired haemolytic anaemia
0.000 0.556 0.444
E29 Testicular dysfunction
0.000 0.559 0.441
M06.4 Inflammatory polyarthropathy
0.438 0.562 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.436 0.564 0.000
C88.7 Other malignant immunoproliferative diseases
0.436 0.564 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.436 0.564 0.000
C88.3 Immunoproliferative small intestinal disease
0.436 0.564 0.000
C88.2 Gamma heavy chain disease
0.436 0.564 0.000
C88.1 Alpha heavy chain disease
0.436 0.564 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.565 0.435
M05 Seropositive rheumatoid arthritis
0.433 0.567 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.575 0.425
E21.4 Other specified disorders of parathyroid gland
0.000 0.575 0.425
E21.2 Other hyperparathyroidism
0.000 0.575 0.425
C84.4 Peripheral T-cell lymphoma
0.421 0.579 0.000
C43 Malignant melanoma of skin
0.421 0.579 0.000
M07.3 Other psoriatic arthropathies
0.419 0.581 0.000
E14.9 Without complications
0.000 0.581 0.419
C84.5 Other and unspecified T-cell lymphomas
0.417 0.582 0.000
E12.9 Without complications
0.000 0.583 0.417
E12.8 With unspecified complications
0.000 0.583 0.417
E12.7 With multiple complications
0.000 0.583 0.417
E12.6 With other specified complications
0.000 0.583 0.417
E12.5 With peripheral circulatory complications
0.000 0.583 0.417
E12.4 With neurological complications
0.000 0.583 0.417
E12.3 With ophthalmic complications
0.000 0.583 0.417
E12.2 With renal complications
0.000 0.583 0.417
E12.1 With ketoacidosis
0.000 0.583 0.417
E12.0 With coma
0.000 0.583 0.417
E34.0 Carcinoid syndrome
0.000 0.583 0.417
D52.8 Other folate deficiency anaemias
0.000 0.586 0.414
D52.1 Drug-induced folate deficiency anaemia
0.000 0.586 0.414
D52.0 Dietary folate deficiency anaemia
0.000 0.586 0.414
C83.0 Small cell (diffuse)
0.410 0.589 0.001
C91.5 Adult T-cell leukaemia
0.408 0.592 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.407 0.593 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.400 0.600 0.000
C95.9 Leukaemia, unspecified
0.399 0.600 0.000
E24.8 Other Cushing's syndrome
0.000 0.601 0.399
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.601 0.399
E24.3 Ectopic ACTH syndrome
0.000 0.601 0.399
E24.2 Drug-induced Cushing's syndrome
0.000 0.601 0.399
E24.1 Nelson's syndrome
0.000 0.601 0.399
E24.0 Pituitary-dependent Cushing's disease
0.000 0.601 0.399
E14.3 With ophthalmic complications
0.000 0.608 0.392
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.390 0.610 0.000
D81.9 Combined immunodeficiency, unspecified
0.000 0.610 0.389
D81.8 Other combined immunodeficiencies
0.000 0.610 0.389
D81.7 Major histocompatibility complex class II deficiency
0.000 0.610 0.389
D81.6 Major histocompatibility complex class I deficiency
0.000 0.610 0.389
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.610 0.389
D81.4 Nezelof's syndrome
0.000 0.610 0.389
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.610 0.389
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.610 0.389
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.610 0.389
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.610 0.389
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.610 0.389
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.610 0.389
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.610 0.389
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.610 0.389
D82.2 Immunodeficiency with short-limbed stature
0.000 0.610 0.389
D82.1 Di George's syndrome
0.000 0.610 0.389
D82.0 Wiskott-Aldrich syndrome
0.000 0.610 0.389
E00-E07 Disorders of thyroid gland
0.000 0.611 0.389
C90.3 Solitary plasmacytoma
0.389 0.611 0.000
C90.1 Plasma cell leukaemia
0.389 0.611 0.000
E14.8 With unspecified complications
0.000 0.611 0.389
E14.7 With multiple complications
0.000 0.611 0.389
E14.2 Withrenal complications
0.000 0.611 0.389
E14.1 With ketoacidosis
0.000 0.611 0.389
E14.0 With coma
0.000 0.611 0.389
D59.1 Other autoimmune haemolytic anaemias
0.000 0.612 0.388
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.386 0.614 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.614 0.385
C91.9 Lymphoid leukaemia, unspecified
0.383 0.616 0.001
D53.8 Other specified nutritional anaemias
0.000 0.624 0.376
D53.2 Scorbutic anaemia
0.000 0.624 0.376
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.624 0.376
D53.0 Protein deficiency anaemia
0.000 0.624 0.376
E14.6 With other specified complications
0.000 0.626 0.374
E25.9 Adrenogenital disorder, unspecified
0.000 0.627 0.373
E25.8 Other adrenogenital disorders
0.000 0.627 0.373
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.627 0.373
E30.9 Disorder of puberty, unspecified
0.000 0.627 0.373
E30.8 Other disorders of puberty
0.000 0.627 0.373
E30.1 Precocious puberty
0.000 0.627 0.373
E30.0 Delayed puberty
0.000 0.627 0.373
E31.9 Polyglandular dysfunction, unspecified
0.000 0.627 0.373
E31.8 Other polyglandular dysfunction
0.000 0.627 0.373
E31.1 Polyglandular hyperfunction
0.000 0.627 0.373
E31.0 Autoimmune polyglandular failure
0.000 0.627 0.373
E32.9 Disease of thymus, unspecified
0.000 0.627 0.373
E32.8 Other diseases of thymus
0.000 0.627 0.373
E32.1 Abscess of thymus
0.000 0.627 0.373
E32.0 Persistent hyperplasia of thymus
0.000 0.627 0.373
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.627 0.373
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.627 0.373
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.627 0.373
C92 Myeloid leukaemia
0.373 0.627 0.000
D57 Sickle-cell disorders
0.000 0.629 0.371
D55 Anaemia due to enzyme disorders
0.000 0.629 0.371
M07.39 Other psoriatic arthropathies (Site unspecified)
0.371 0.629 0.000
E14.5 With peripheral circulatory complications
0.000 0.630 0.370
C43.6 Malignant melanoma of upper limb, including shoulder
0.370 0.630 0.000
E20.8 Other hypoparathyroidism
0.000 0.631 0.369
E20.1 Pseudohypoparathyroidism
0.000 0.631 0.369
E20.0 Idiopathic hypoparathyroidism
0.000 0.631 0.369
C43.4 Malignant melanoma of scalp and neck
0.366 0.634 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.637 0.363
C02 Malignant neoplasm of other and unspecified parts of tongue
0.363 0.637 0.000
E34.5 Androgen resistance syndrome
0.000 0.638 0.361
E34.4 Constitutional tall stature
0.000 0.638 0.361
E34.3 Short stature, not elsewhere classified
0.000 0.638 0.361
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.638 0.361
E34.1 Other hypersecretion of intestinal hormones
0.000 0.638 0.361
E21.3 Hyperparathyroidism, unspecified
0.000 0.641 0.359
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.642 0.358
E45 Retarded development following protein-energy malnutrition
0.000 0.642 0.358
E43 Unspecified severe protein-energy malnutrition
0.000 0.642 0.358
E42 Marasmic kwashiorkor
0.000 0.642 0.358
E41 Nutritional marasmus
0.000 0.642 0.358
E40 Kwashiorkor
0.000 0.642 0.358
C88.0 Waldenstrom's macroglobulinaemia
0.357 0.642 0.000
J45 Asthma
0.000 0.647 0.353
D53.9 Nutritional anaemia, unspecified
0.000 0.647 0.353
C74 Malignant neoplasm of adrenal gland
0.349 0.651 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.651 0.349
C90.0 Multiple myeloma
0.345 0.655 0.000
M12 Other specific arthropathies
0.344 0.656 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.344 0.656 0.000
M08 Juvenile arthritis
0.344 0.656 0.000
M14 Arthropathies in other diseases classified elsewhere
0.344 0.656 0.000
E14.4 With neurological complications
0.000 0.657 0.343
E03 Other hypothyroidism
0.000 0.658 0.342
C91.8 Mature B-cell leukaemia Burkitt-type
0.341 0.659 0.001
C91.7 Other lymphoid leukaemia
0.341 0.659 0.001
C91.6 Prolymphocytic leukaemia of T-cell type
0.341 0.659 0.001
C91.3 Prolymphocytic leukaemia
0.341 0.659 0.001
C91.2 Subacute lymphocytic leukaemia
0.341 0.659 0.001
D83.8 Other common variable immunodeficiencies
0.000 0.660 0.339
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.660 0.339
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.660 0.339
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.660 0.339
C81.9 Hodgkin's disease, unspecified
0.336 0.663 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.336 0.664 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.336 0.664 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.664 0.336
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.335 0.665 0.000
M11 Other crystal arthropathies
0.334 0.665 0.000
E28 Ovarian dysfunction
0.000 0.666 0.334
C40-C41 Malignant neoplasms of bone and articular cartilage
0.333 0.666 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.333 0.666 0.000
E66 Obesity
0.000 0.667 0.333
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.331 0.669 0.000
E67 Other hyperalimentation
0.000 0.669 0.331
E68 Sequelae of hyperalimentation
0.000 0.669 0.331
M06.19 Adult-onset Still's disease (Site unspecified)
0.330 0.669 0.000
M06.18 Adult-onset Still's disease (Other)
0.330 0.669 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.330 0.669 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.330 0.669 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.330 0.669 0.000
M06.14 Adult-onset Still's disease (Hand)
0.330 0.669 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.330 0.669 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.330 0.669 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.330 0.669 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.330 0.669 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.330 0.669 0.000
M06.28 Rheumatoid bursitis (Other)
0.330 0.669 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.330 0.669 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.330 0.669 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.330 0.669 0.000
M06.24 Rheumatoid bursitis (Hand)
0.330 0.669 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.330 0.669 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.330 0.669 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.330 0.669 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.330 0.669 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.330 0.669 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.330 0.669 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.330 0.669 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.330 0.669 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.330 0.669 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.330 0.669 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.330 0.669 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.330 0.669 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.330 0.669 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.330 0.669 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.670 0.330
C02.1 Border of tongue
0.329 0.670 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.329 0.671 0.000
E34.8 Other specified endocrine disorders
0.000 0.671 0.328
C75 Malignant neoplasm of other endocrine glands and related structures
0.327 0.672 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.325 0.674 0.000
M06.38 Rheumatoid nodule (Other)
0.325 0.674 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.325 0.674 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.325 0.674 0.000
M06.33 Rheumatoid nodule (Forearm)
0.325 0.674 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.325 0.674 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.325 0.674 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.674 0.325
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.674 0.325
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.674 0.325
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.674 0.325
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.674 0.325
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.674 0.325
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.674 0.325
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.674 0.325
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.674 0.325
M06.34 Rheumatoid nodule (Hand)
0.325 0.675 0.000
E50-E64 Other nutritional deficiencies
0.000 0.675 0.324
C06 Malignant neoplasm of other and unspecified parts of mouth
0.324 0.676 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.322 0.678 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.320 0.680 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.319 0.681 0.000
M07.6 Other enteropathic arthropathies
0.319 0.681 0.000
M07.5 Arthropathy in ulcerative colitis
0.319 0.681 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.319 0.681 0.000
M07.2 Psoriatic spondylitis
0.319 0.681 0.000
M07.1 Arthritis mutilans
0.319 0.681 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.319 0.681 0.000
D84.8 Other specified immunodeficiencies
0.001 0.681 0.318
D84.1 Defects in the complement system
0.001 0.681 0.318
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.001 0.681 0.318
D59.8 Other acquired haemolytic anaemias
0.000 0.682 0.318
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.682 0.318
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.682 0.318
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.682 0.318
D59.3 Haemolytic-uraemic syndrome
0.000 0.682 0.318
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.682 0.318
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.682 0.318
M45.X9 Ankylosing spondylitis (Site unspecified)
0.318 0.682 0.000
C05 Malignant neoplasm of palate
0.317 0.683 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.316 0.683 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.684 0.316
E29.8 Other testicular dysfunction
0.000 0.684 0.316
E29.0 Testicular hyperfunction
0.000 0.684 0.316
E46 Unspecified protein-energy malnutrition
0.000 0.684 0.316
M06.48 Inflammatory polyarthropathy (Other)
0.314 0.686 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.314 0.686 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.314 0.686 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.314 0.686 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.314 0.686 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.314 0.686 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.314 0.686 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.314 0.686 0.000
D56 Thalassaemia
0.000 0.686 0.314
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.687 0.313
E03.9 Hypothyroidism, unspecified
0.000 0.688 0.312
C90.2 Plasmacytoma, extramedullary
0.312 0.688 0.000
M05.8 Other seropositive rheumatoid arthritis
0.311 0.689 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.311 0.689 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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