TreeWAS – Variant ID: rs17433780

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E27 Other disorders of adrenal gland	0.457	0.543	0.000
E20-E35 Disorders of other endocrine glands	0.453	0.547	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.442	0.558	0.000
E21.0 Primary hyperparathyroidism	0.433	0.567	0.000
E27.1 Primary adrenocortical insufficiency	0.421	0.579	0.000
E27.2 Addisonian crisis	0.416	0.584	0.000
E29 Testicular dysfunction	0.416	0.584	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.404	0.596	0.000
E27.8 Other specified disorders of adrenal gland	0.391	0.609	0.000
E29.1 Testicular hypofunction	0.389	0.611	0.000
E10-E14 Diabetes mellitus	0.388	0.612	0.000
E10 Insulin-dependent diabetes mellitus	0.384	0.616	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.383	0.617	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.383	0.617	0.000
E10.0 With coma	0.366	0.634	0.000
E34 Other endocrine disorders	0.364	0.635	0.000
E40-E46 Malnutrition	0.355	0.644	0.000
E10.9 Without complications	0.351	0.649	0.000
E11 Non-insulin-dependent diabetes mellitus	0.350	0.650	0.000
E21.3 Hyperparathyroidism, unspecified	0.345	0.655	0.000
E14 Unspecified diabetes mellitus	0.344	0.656	0.000
E46 Unspecified protein-energy malnutrition	0.336	0.664	0.000
E23 Hypofunction and other disorders of pituitary gland	0.332	0.668	0.000
E27.5 Adrenomedullary hyperfunction	0.327	0.672	0.000
E27.0 Other adrenocortical overactivity	0.327	0.672	0.000
E31 Polyglandular dysfunction	0.326	0.674	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.325	0.675	0.000
E32 Diseases of thymus	0.325	0.675	0.000
E30 Disorders of puberty, not elsewhere classified	0.325	0.675	0.000
E25 Adrenogenital disorders	0.325	0.675	0.000
E26 Hyperaldosteronism	0.323	0.676	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.323	0.677	0.000
E11.0 With coma	0.322	0.678	0.000
E11.8 With unspecified complications	0.320	0.680	0.000
E24 Cushing's syndrome	0.319	0.681	0.000
E21.4 Other specified disorders of parathyroid gland	0.317	0.683	0.000
E21.2 Other hyperparathyroidism	0.313	0.687	0.000
E10.7 With multiple complications	0.310	0.690	0.000
E10.1 With ketoacidosis	0.308	0.692	0.000
E11.5 With peripheral circulatory complications	0.307	0.693	0.000
E27.9 Disorder of adrenal gland, unspecified	0.304	0.696	0.000
E10.3 With ophthalmic complications	0.304	0.696	0.000
E34.8 Other specified endocrine disorders	0.303	0.697	0.000
E14.5 With peripheral circulatory complications	0.301	0.699	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.299	0.701	0.000
E11.2 With renal complications	0.299	0.701	0.000
E29.9 Testicular dysfunction, unspecified	0.298	0.702	0.000
E29.8 Other testicular dysfunction	0.298	0.702	0.000
E29.0 Testicular hyperfunction	0.298	0.702	0.000
E10.4 With neurological complications	0.297	0.703	0.000
E22 Hyperfunction of pituitary gland	0.290	0.710	0.000
E34.9 Endocrine disorder, unspecified	0.283	0.717	0.000
E10.8 With unspecified complications	0.280	0.720	0.000
E14.1 With ketoacidosis	0.279	0.721	0.000
E12 Malnutrition-related diabetes mellitus	0.278	0.722	0.000
E14.6 With other specified complications	0.274	0.726	0.000
E14.8 With unspecified complications	0.273	0.727	0.000
E20 Hypoparathyroidism	0.269	0.731	0.000
E23.0 Hypopituitarism	0.263	0.737	0.000
E34.5 Androgen resistance syndrome	0.261	0.738	0.000
E34.4 Constitutional tall stature	0.261	0.738	0.000
E34.3 Short stature, not elsewhere classified	0.261	0.738	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.261	0.738	0.000
E34.1 Other hypersecretion of intestinal hormones	0.261	0.738	0.000
E23.2 Diabetes insipidus	0.260	0.740	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.255	0.745	0.000
E45 Retarded development following protein-energy malnutrition	0.255	0.745	0.000
E43 Unspecified severe protein-energy malnutrition	0.255	0.745	0.000
E42 Marasmic kwashiorkor	0.255	0.745	0.000
E41 Nutritional marasmus	0.255	0.745	0.000
E40 Kwashiorkor	0.255	0.745	0.000
E14.3 With ophthalmic complications	0.252	0.748	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.252	0.748	0.000
E11.7 With multiple complications	0.251	0.749	0.000
E50-E64 Other nutritional deficiencies	0.248	0.752	0.000
E14.7 With multiple complications	0.247	0.753	0.000
E14.2 Withrenal complications	0.247	0.753	0.000
E14.0 With coma	0.247	0.753	0.000
E10.5 With peripheral circulatory complications	0.244	0.756	0.000
E24.9 Cushing's syndrome, unspecified	0.243	0.757	0.000
E22.1 Hyperprolactinaemia	0.241	0.759	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.238	0.762	0.000
E23.1 Drug-induced hypopituitarism	0.238	0.762	0.000
E31.0 Autoimmune polyglandular failure	0.236	0.764	0.000
E31.9 Polyglandular dysfunction, unspecified	0.234	0.766	0.000
E31.8 Other polyglandular dysfunction	0.234	0.766	0.000
E31.1 Polyglandular hyperfunction	0.234	0.766	0.000
E26.0 Primary hyperaldosteronism	0.234	0.766	0.000
E25.9 Adrenogenital disorder, unspecified	0.233	0.767	0.000
E25.8 Other adrenogenital disorders	0.233	0.767	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.233	0.767	0.000
E30.9 Disorder of puberty, unspecified	0.233	0.767	0.000
E30.8 Other disorders of puberty	0.233	0.767	0.000
E30.1 Precocious puberty	0.233	0.767	0.000
E30.0 Delayed puberty	0.233	0.767	0.000
E32.9 Disease of thymus, unspecified	0.233	0.767	0.000
E32.8 Other diseases of thymus	0.233	0.767	0.000
E32.1 Abscess of thymus	0.233	0.767	0.000
E32.0 Persistent hyperplasia of thymus	0.233	0.767	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.233	0.767	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.233	0.767	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.233	0.767	0.000
E26.8 Other hyperaldosteronism	0.232	0.768	0.000
E26.1 Secondary hyperaldosteronism	0.232	0.768	0.000
E34.0 Carcinoid syndrome	0.230	0.770	0.000
E26.9 Hyperaldosteronism, unspecified	0.229	0.771	0.000
E24.8 Other Cushing's syndrome	0.229	0.771	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.229	0.771	0.000
E24.3 Ectopic ACTH syndrome	0.229	0.771	0.000
E24.1 Nelson's syndrome	0.229	0.771	0.000
E11.6 With other specified complications	0.227	0.773	0.000
E10.2 With renal complications	0.227	0.773	0.000
E61 Deficiency of other nutrient elements	0.225	0.775	0.000
E11.1 With ketoacidosis	0.225	0.775	0.000
E10.6 With other specified complications	0.224	0.776	0.000
E13 Other specified diabetes mellitus	0.223	0.777	0.000
E23.6 Other disorders of pituitary gland	0.223	0.777	0.000
E28 Ovarian dysfunction	0.221	0.779	0.000
E24.2 Drug-induced Cushing's syndrome	0.221	0.779	0.000
E24.0 Pituitary-dependent Cushing's disease	0.214	0.786	0.000
E61.1 Iron deficiency	0.212	0.788	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.208	0.792	0.000
E22.8 Other hyperfunction of pituitary gland	0.208	0.792	0.000
E14.4 With neurological complications	0.207	0.793	0.000
E22.0 Acromegaly and pituitary gigantism	0.206	0.794	0.000
E11.4 With neurological complications	0.205	0.795	0.000
E12.9 Without complications	0.200	0.800	0.000
E12.8 With unspecified complications	0.200	0.800	0.000
E12.7 With multiple complications	0.200	0.800	0.000
E12.6 With other specified complications	0.200	0.800	0.000
E12.5 With peripheral circulatory complications	0.200	0.800	0.000
E12.4 With neurological complications	0.200	0.800	0.000
E12.3 With ophthalmic complications	0.200	0.800	0.000
E12.2 With renal complications	0.200	0.800	0.000
E12.1 With ketoacidosis	0.200	0.800	0.000
E12.0 With coma	0.200	0.800	0.000
E23.7 Disorder of pituitary gland, unspecified	0.199	0.801	0.000
E58 Dietary calcium deficiency	0.195	0.805	0.000
E20.8 Other hypoparathyroidism	0.193	0.807	0.000
E20.1 Pseudohypoparathyroidism	0.193	0.807	0.000
E20.0 Idiopathic hypoparathyroidism	0.193	0.807	0.000
E14.9 Without complications	0.191	0.809	0.000
E65-E68 Obesity and other hyperalimentation	0.183	0.817	0.000
E44.1 Mild protein-energy malnutrition	0.183	0.817	0.000
E44.0 Moderate protein-energy malnutrition	0.183	0.817	0.000
E15 Nondiabetic hypoglycaemic coma	0.181	0.819	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.178	0.822	0.000
E63 Other nutritional deficiencies	0.178	0.822	0.000
E50 Vitamin A deficiency	0.178	0.822	0.000
E60 Dietary zinc deficiency	0.178	0.822	0.000
E59 Dietary selenium deficiency	0.178	0.822	0.000
E54 Ascorbic acid deficiency	0.178	0.822	0.000
E52 Niacin deficiency [pellagra]	0.178	0.822	0.000
E56 Other vitamin deficiencies	0.173	0.827	0.000
E51 Thiamine deficiency	0.168	0.832	0.000
E11.3 With ophthalmic complications	0.167	0.833	0.000
E61.9 Deficiency of nutrient element, unspecified	0.161	0.838	0.000
E61.8 Deficiency of other specified nutrient elements	0.161	0.838	0.000
E61.7 Deficiency of multiple nutrient elements	0.161	0.838	0.000
E61.6 Vanadium deficiency	0.161	0.838	0.000
E61.5 Molybdenum deficiency	0.161	0.838	0.000
E61.4 Chromium deficiency	0.161	0.838	0.000
E61.3 Manganese deficiency	0.161	0.838	0.000
E61.0 Copper deficiency	0.161	0.838	0.000
E13.8 With unspecified complications	0.160	0.840	0.000
E13.7 With multiple complications	0.160	0.840	0.000
E13.6 With other specified complications	0.160	0.840	0.000
E13.5 With peripheral circulatory complications	0.160	0.840	0.000
E13.4 With neurological complications	0.160	0.840	0.000
E13.2 With renal complications	0.160	0.840	0.000
E13.1 With ketoacidosis	0.160	0.840	0.000
E13.0 With coma	0.160	0.840	0.000
E28.9 Ovarian dysfunction, unspecified	0.159	0.841	0.000
E28.8 Other ovarian dysfunction	0.159	0.841	0.000
E28.1 Androgen excess	0.159	0.841	0.000
E28.0 Oestrogen excess	0.159	0.841	0.000
E16 Other disorders of pancreatic internal secretion	0.159	0.841	0.000
E61.2 Magnesium deficiency	0.149	0.851	0.000
E13.3 With ophthalmic complications	0.145	0.855	0.000
E65 Localised adiposity	0.138	0.862	0.000
E20.9 Hypoparathyroidism, unspecified	0.137	0.863	0.000
E67 Other hyperalimentation	0.132	0.868	0.000
E68 Sequelae of hyperalimentation	0.132	0.868	0.000
E28.2 Polycystic ovarian syndrome	0.131	0.869	0.000
E50.9 Vitamin A deficiency, unspecified	0.127	0.872	0.000
E50.8 Other manifestations of vitamin A deficiency	0.127	0.872	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.127	0.872	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.127	0.872	0.000
E50.5 Vitamin A deficiency with night blindness	0.127	0.872	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.127	0.872	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.127	0.872	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.127	0.872	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.127	0.872	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.127	0.872	0.000
E63.9 Nutritional deficiency, unspecified	0.127	0.872	0.000
E63.8 Other specified nutritional deficiencies	0.127	0.872	0.000
E63.1 Imbalance of constituents of food intake	0.127	0.872	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.127	0.872	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.127	0.872	0.000
E64.8 Sequelae of other nutritional deficiencies	0.127	0.872	0.000
E64.3 Sequelae of rickets	0.127	0.872	0.000
E64.2 Sequelae of vitamin C deficiency	0.127	0.872	0.000
E64.1 Sequelae of vitamin A deficiency	0.127	0.872	0.000
E64.0 Sequelae of protein-energy malnutrition	0.127	0.872	0.000
E13.9 Without complications	0.127	0.873	0.000
E56.9 Vitamin deficiency, unspecified	0.124	0.876	0.000
E56.8 Deficiency of other vitamins	0.124	0.876	0.000
E56.0 Deficiency of vitamin E	0.124	0.876	0.000
E16.1 Other hypoglycaemia	0.120	0.879	0.000
E51.9 Thiamine deficiency, unspecified	0.120	0.879	0.000
E51.8 Other manifestations of thiamine deficiency	0.120	0.879	0.000
E51.1 Beriberi	0.120	0.879	0.000
E56.1 Deficiency of vitamin K	0.119	0.881	0.000
E55 Vitamin D deficiency	0.118	0.881	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.114	0.886	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.114	0.886	0.000
E16.4 Abnormal secretion of gastrin	0.114	0.886	0.000
E16.3 Increased secretion of glucagon	0.114	0.886	0.000
E51.2 Wernicke's encephalopathy	0.110	0.889	0.000
E28.3 Primary ovarian failure	0.106	0.894	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.102	0.898	0.000
E16.2 Hypoglycaemia, unspecified	0.102	0.898	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.097	0.903	0.000
E67.8 Other specified hyperalimentation	0.094	0.905	0.000
E67.3 Hypervitaminosis D	0.094	0.905	0.000
E67.2 Megavitamin-B6 syndrome	0.094	0.905	0.000
E67.1 Hypercarotenaemia	0.094	0.905	0.000
E67.0 Hypervitaminosis A	0.094	0.905	0.000
E55.0 Rickets, active	0.085	0.915	0.000
E53 Deficiency of other B group vitamins	0.073	0.927	0.000
E53.1 Pyridoxine deficiency	0.052	0.947	0.000
E53.0 Riboflavin deficiency	0.052	0.947	0.000
E53.9 Vitamin B deficiency, unspecified	0.034	0.965	0.001
Z63 Other problems related to primary support group, including family circumstances	0.033	0.967	0.000
K55.0 Acute vascular disorders of intestine	0.032	0.968	0.000
Z63.0 Problems in relationship with spouse or partner	0.032	0.968	0.000
Z60.2 Living alone	0.030	0.970	0.000
Z60 Problems related to social environment	0.030	0.970	0.000
Z63.4 Disappearance and death of family member	0.029	0.971	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.029	0.971	0.000
Z63.5 Disruption of family by separation and divorce	0.028	0.972	0.000
Z63.6 Dependent relative needing care at home	0.027	0.973	0.000
Z63.8 Other specified problems related to primary support group	0.027	0.973	0.000
E55.9 Vitamin D deficiency, unspecified	0.026	0.974	0.000
Z58 Problems related to physical environment	0.026	0.974	0.000
Z63.7 Other stressful life events affecting family and household	0.024	0.976	0.000
Z63.9 Problem related to primary support group, unspecified	0.024	0.976	0.000
Z63.3 Absence of family member	0.024	0.976	0.000
Z63.2 Inadequate family support	0.024	0.976	0.000
Z63.1 Problems in relationship with parents and in-laws	0.024	0.976	0.000
K55 Vascular disorders of intestine	0.024	0.976	0.000
Z65 Problems related to other psychosocial circumstances	0.024	0.976	0.000
Z60.8 Other problems related to social environment	0.024	0.976	0.000
Z59 Problems related to housing and economic circumstances	0.024	0.976	0.000
K55.2 Angiodysplasia of colon	0.024	0.976	0.000
E00-E07 Disorders of thyroid gland	0.023	0.977	0.000
Z60.9 Problem related to social environment, unspecified	0.022	0.977	0.000
Z58.5 Exposure to other pollution	0.022	0.978	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.021	0.978	0.000
Z60.4 Social exclusion and rejection	0.021	0.978	0.000
Z60.3 Acculturation difficulty	0.021	0.978	0.000
Z60.1 Atypical parenting situation	0.021	0.978	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.021	0.978	0.000
Z62 Other problems related to upbringing	0.021	0.979	0.000
Z55 Problems related to education and literacy	0.021	0.979	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.021	0.979	0.000
Z58.1 Exposure to air pollution	0.020	0.979	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.020	0.980	0.000
E70-E90 Metabolic disorders	0.020	0.980	0.000
Z61 Problems related to negative life events in childhood	0.020	0.980	0.000
Z58.8 Other problems related to physical environment	0.020	0.980	0.000
K55.1 Chronic vascular disorders of intestine	0.020	0.980	0.000
E66 Obesity	0.019	0.981	0.000
E86 Volume depletion	0.019	0.981	0.000
Z58.9 Problem related to physical environment, unspecified	0.019	0.981	0.000
Z58.6 Inadequate drinking-water supply	0.019	0.981	0.000
Z58.4 Exposure to radiation	0.019	0.981	0.000
Z58.3 Exposure to soil pollution	0.019	0.981	0.000
Z58.2 Exposure to water pollution	0.019	0.981	0.000
Z58.0 Exposure to noise	0.019	0.981	0.000
Z58.7 Exposure to tobacco smoke	0.019	0.981	0.000
Z59.4 Lack of adequate food	0.019	0.981	0.000
Z64 Problems related to certain psychosocial circumstances	0.018	0.981	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.018	0.982	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.018	0.982	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.017	0.982	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.017	0.982	0.000
Z65.4 Victim of crime and terrorism	0.017	0.982	0.000
Z65.3 Problems related to other legal circumstances	0.017	0.982	0.000
Z65.2 Problems related to release from prison	0.017	0.982	0.000
Z65.1 Imprisonment and other incarceration	0.017	0.982	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.017	0.982	0.000
K55.8 Other vascular disorders of intestine	0.017	0.983	0.000
Z59.7 Insufficient social insurance and welfare support	0.017	0.983	0.000
Z59.6 Low income	0.017	0.983	0.000
Z59.5 Extreme poverty	0.017	0.983	0.000
Z59.3 Problems related to living in residential institution	0.017	0.983	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.017	0.983	0.000
E00 Congenital iodine-deficiency syndrome	0.017	0.983	0.000
Z56 Problems related to employment and unemployment	0.016	0.983	0.000
Z59.1 Inadequate housing	0.016	0.984	0.000
E03 Other hypothyroidism	0.016	0.984	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.016	0.984	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.015	0.985	0.000
Z55.8 Other problems relating to education and literacy	0.015	0.985	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.015	0.985	0.000
Z55.3 Underachievement in school	0.015	0.985	0.000
Z55.2 Failed examinations	0.015	0.985	0.000
Z55.1 Schooling unavailable and unattainable	0.015	0.985	0.000
Z55.0 Illiteracy and low-level literacy	0.015	0.985	0.000
Z62.9 Problem related to upbringing, unspecified	0.015	0.985	0.000
Z62.8 Other specified problems related to upbringing	0.015	0.985	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.015	0.985	0.000
Z62.5 Other problems related to neglect in upbringing	0.015	0.985	0.000
Z62.4 Emotional neglect of child	0.015	0.985	0.000
Z62.3 Hostility towards and scapegoating of child	0.015	0.985	0.000
Z62.2 Institutional upbringing	0.015	0.985	0.000
Z62.1 Parental overprotection	0.015	0.985	0.000
Z62.0 Inadequate parental supervision and control	0.015	0.985	0.000
E85 Amyloidosis	0.015	0.985	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.015	0.985	0.000
E77 Disorders of glycoprotein metabolism	0.015	0.985	0.000
E76 Disorders of glycosaminoglycan metabolism	0.015	0.985	0.000
E72 Other disorders of amino-acid metabolism	0.015	0.985	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.015	0.985	0.000
E70 Disorders of aromatic amino-acid metabolism	0.015	0.985	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.015	0.985	0.000
Z59.0 Homelessness	0.015	0.985	0.000
Z61.9 Negative life events in childhood, unspecified	0.014	0.985	0.000
Z61.8 Other negative life events in childhood	0.014	0.985	0.000
Z61.7 Personal frightening experience in childhood	0.014	0.985	0.000
Z61.6 Problems related to alleged physical abuse of child	0.014	0.985	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.014	0.985	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.014	0.985	0.000
Z61.2 Altered pattern of family relationships in childhood	0.014	0.985	0.000
Z61.1 Removal from home in childhood	0.014	0.985	0.000
Z61.0 Loss of love relationship in childhood	0.014	0.985	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.014	0.985	0.000
E74 Other disorders of carbohydrate metabolism	0.014	0.986	0.000
E03.8 Other specified hypothyroidism	0.014	0.986	0.000
E66.1 Drug-induced obesity	0.014	0.986	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.014	0.986	0.000
E73 Lactose intolerance	0.014	0.986	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.013	0.986	0.000
Z64.4 Discord with counsellors	0.013	0.986	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.013	0.986	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.013	0.986	0.000
Z64.1 Problems related to multiparity	0.013	0.986	0.000
E79 Disorders of purine and pyrimidine metabolism	0.013	0.986	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.013	0.987	0.000
E84 Cystic fibrosis	0.013	0.987	0.000
E85.9 Amyloidosis, unspecified	0.013	0.987	0.000
E80.6 Other disorders of bilirubin metabolism	0.013	0.987	0.000
E80.2 Other porphyria	0.012	0.987	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.012	0.988	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.012	0.988	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.012	0.988	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.012	0.988	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.012	0.988	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.012	0.988	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.012	0.988	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.012	0.988	0.000
E03.1 Congenital hypothyroidism without goitre	0.012	0.988	0.000
E89.3 Postprocedural hypopituitarism	0.012	0.988	0.000
Z56.7 Other and unspecified problems related to employment	0.012	0.988	0.000
Z56.5 Uncongenial work	0.012	0.988	0.000
Z56.4 Discord with boss and workmates	0.012	0.988	0.000
Z56.2 Threat of job loss	0.012	0.988	0.000
Z56.1 Change of job	0.012	0.988	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.012	0.988	0.000
Z56.0 Unemployment, unspecified	0.012	0.988	0.000
E06 Thyroiditis	0.012	0.988	0.000
K55.9 Vascular disorder of intestine, unspecified	0.012	0.988	0.000
E03.5 Myxoedema coma	0.011	0.988	0.000
E03.4 Atrophy of thyroid (acquired)	0.011	0.988	0.000
E03.3 Postinfectious hypothyroidism	0.011	0.988	0.000
E89.5 Postprocedural testicular hypofunction	0.011	0.989	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.011	0.989	0.000
E80.5 Crigler-Najjar syndrome	0.011	0.989	0.000
E80.3 Defects of catalase and peroxydase	0.011	0.989	0.000
E80.0 Hereditary erythropoietic porphyria	0.011	0.989	0.000
Z57 Occupational exposure to risk-factors	0.011	0.989	0.000
Z56.3 Stressful work schedule	0.011	0.989	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.011	0.989	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.011	0.989	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.011	0.989	0.000
E89.2 Postprocedural hypoparathyroidism	0.011	0.989	0.000
E80.1 Porphyria cutanea tarda	0.011	0.989	0.000
E85.4 Organ-limited amyloidosis	0.011	0.989	0.000
Z64.0 Problems related to unwanted pregnancy	0.011	0.989	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.011	0.989	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.011	0.989	0.000
E70.3 Albinism	0.011	0.989	0.000
E70.2 Disorders of tyrosine metabolism	0.011	0.989	0.000
E70.1 Other hyperphenylalaninaemias	0.011	0.989	0.000
E70.0 Classical phenylketonuria	0.011	0.989	0.000
E71.3 Disorders of fatty-acid metabolism	0.011	0.989	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.011	0.989	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.011	0.989	0.000
E71.0 Maple-syrup-urine disease	0.011	0.989	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.011	0.989	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.011	0.989	0.000
E72.5 Disorders of glycine metabolism	0.011	0.989	0.000
E72.4 Disorders of ornithine metabolism	0.011	0.989	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.011	0.989	0.000
E72.2 Disorders of urea cycle metabolism	0.011	0.989	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.011	0.989	0.000
E72.0 Disorders of amino-acid transport	0.011	0.989	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.011	0.989	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.011	0.989	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.011	0.989	0.000
E76.2 Other mucopolysaccharidoses	0.011	0.989	0.000
E76.1 Mucopolysaccharidosis, type II	0.011	0.989	0.000
E76.0 Mucopolysaccharidosis, type I	0.011	0.989	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.011	0.989	0.000
E77.8 Other disorders of glycoprotein metabolism	0.011	0.989	0.000
E77.1 Defects in glycoprotein degradation	0.011	0.989	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.011	0.989	0.000
E85.8 Other amyloidosis	0.011	0.989	0.000
E75.6 Lipid storage disorder, unspecified	0.011	0.989	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.011	0.989	0.000
E75.3 Sphingolipidosis, unspecified	0.011	0.989	0.000
E75.2 Other sphingolipidosis	0.011	0.989	0.000
E75.1 Other gangliosidosis	0.011	0.989	0.000
E75.0 GM2 gangliosidosis	0.011	0.989	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.010	0.989	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.010	0.989	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.010	0.989	0.000
E74.2 Disorders of galactose metabolism	0.010	0.989	0.000
E74.1 Disorders of fructose metabolism	0.010	0.989	0.000
E74.0 Glycogen storage disease	0.010	0.989	0.000
E75.5 Other lipid storage disorders	0.010	0.989	0.000
E89.1 Postprocedural hypoinsulinaemia	0.010	0.990	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.010	0.990	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.010	0.990	0.000
E89.4 Postprocedural ovarian failure	0.010	0.990	0.000
E73.8 Other lactose intolerance	0.010	0.990	0.000
E73.1 Secondary lactase deficiency	0.010	0.990	0.000
E73.0 Congenital lactase deficiency	0.010	0.990	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.010	0.990	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.010	0.990	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.010	0.990	0.000
E79.1 Lesch-Nyhan syndrome	0.010	0.990	0.000
E66.0 Obesity due to excess calories	0.010	0.990	0.000
E84.8 Cystic fibrosis with other manifestations	0.010	0.990	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.010	0.990	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.010	0.990	0.000
E80.4 Gilbert's syndrome	0.010	0.990	0.000
Z56.6 Other physical and mental strain related to work	0.009	0.991	0.000
E06.1 Subacute thyroiditis	0.009	0.991	0.000
E85.3 Secondary systemic amyloidosis	0.009	0.991	0.000
Z57.8 Occupational exposure to other risk-factors	0.009	0.991	0.000
E07 Other disorders of thyroid	0.009	0.991	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.009	0.991	0.000
E73.9 Lactose intolerance, unspecified	0.009	0.991	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.009	0.991	0.000
M86.9 Osteomyelitis, unspecified	0.009	0.991	0.000
E06.4 Drug-induced thyroiditis	0.009	0.991	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.009	0.991	0.000
E06.0 Acute thyroiditis	0.009	0.991	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.008	0.991	0.000
G91.9 Hydrocephalus, unspecified	0.009	0.991	0.000
E06.5 Other chronic thyroiditis	0.008	0.991	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.009	0.991	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.008	0.992	0.000
Z57.7 Occupational exposure to vibration	0.008	0.992	0.000
Z57.6 Occupational exposure to extreme temperature	0.008	0.992	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.008	0.992	0.000
Z57.1 Occupational exposure to radiation	0.008	0.992	0.000
Z57.0 Occupational exposure to noise	0.008	0.992	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.008	0.992	0.000
E84.9 Cystic fibrosis, unspecified	0.008	0.992	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.008	0.992	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.008	0.992	0.000
E88 Other metabolic disorders	0.007	0.992	0.000
E06.9 Thyroiditis, unspecified	0.007	0.993	0.000
E53.8 Deficiency of other specified B group vitamins	0.007	0.993	0.000
Z57.3 Occupational exposure to other air contaminants	0.007	0.993	0.000
E07.1 Dyshormogenetic goitre	0.007	0.993	0.000
E07.0 Hypersecretion of calcitonin	0.007	0.993	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.007	0.993	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.993	0.007
M86.93 Osteomyelitis, unspecified (Forearm)	0.006	0.993	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.006	0.993	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.006	0.993	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.006	0.993	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.006	0.994	0.000
M86 Osteomyelitis	0.006	0.994	0.000
E88.8 Other specified metabolic disorders	0.006	0.994	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M25.57 Pain in joint (Ankle and foot)	0.006	0.994	0.000
E88.9 Metabolic disorder, unspecified	0.005	0.994	0.000
G91 Hydrocephalus	0.006	0.994	0.000
Y43.3 Other antineoplastic drugs	0.006	0.994	0.000
E88.3 Tumour lysis syndrome	0.005	0.995	0.000
E07.8 Other specified disorders of thyroid	0.005	0.995	0.000
R82.9 Other and unspecified abnormal finding in urine	0.005	0.995	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.995	0.005
G91.0 Communicating hydrocephalus	0.005	0.995	0.000
G91.8 Other hydrocephalus	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations