TreeWAS – Variant ID: rs174528

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.2 Calculus of gallbladder without cholecystitis	0.995	0.005	0.000
K80 Cholelithiasis	0.499	0.501	0.000
K80.4 Calculus of bile duct with cholecystitis	0.439	0.561	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.427	0.573	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.372	0.628	0.000
K80.3 Calculus of bile duct with cholangitis	0.358	0.642	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.685	0.315
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.257	0.743	0.000
K80.8 Other cholelithiasis	0.229	0.771	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.214	0.786	0.000
J33.0 Polyp of nasal cavity	0.000	0.818	0.182
J33 Nasal polyp	0.000	0.824	0.176
J33.9 Nasal polyp, unspecified	0.000	0.829	0.171
J33.8 Other polyp of sinus	0.000	0.834	0.166
E03 Other hypothyroidism	0.000	0.872	0.128
J33.1 Polypoid sinus degeneration	0.000	0.872	0.128
H00.1 Chalazion	0.000	0.902	0.098
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.904	0.096
E03.1 Congenital hypothyroidism without goitre	0.000	0.906	0.093
E03.5 Myxoedema coma	0.000	0.908	0.092
E03.4 Atrophy of thyroid (acquired)	0.000	0.908	0.092
E03.3 Postinfectious hypothyroidism	0.000	0.908	0.092
E03.8 Other specified hypothyroidism	0.000	0.911	0.088
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.916	0.084
R01.1 Cardiac murmur, unspecified	0.000	0.924	0.076
N83.2 Other and unspecified ovarian cysts	0.056	0.944	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.045	0.955	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.042	0.958	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.042	0.958	0.000
H00 Hordeolum and chalazion	0.000	0.959	0.041
N83.3 Acquired atrophy of ovary and Fallopian tube	0.041	0.959	0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.037	0.963	0.000
D12.5 Sigmoid colon	0.000	0.964	0.036
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.033	0.967	0.000
N83.7 Haematoma of broad ligament	0.032	0.967	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.969	0.031
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.971	0.029
N83.6 Haematosalpinx	0.029	0.971	0.000
K83 Other diseases of biliary tract	0.028	0.972	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.028	0.972	0.000
K63.5 Polyp of colon	0.000	0.972	0.028
D12.2 Ascending colon	0.000	0.973	0.027
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.973	0.027
K83.1 Obstruction of bile duct	0.026	0.974	0.000
N83.1 Corpus luteum cyst	0.025	0.975	0.000
D12.0 Caecum	0.000	0.975	0.025
K83.0 Cholangitis	0.025	0.975	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.024	0.976	0.000
D25.9 Leiomyoma of uterus, unspecified	0.024	0.976	0.000
D12.7 Rectosigmoid junction	0.000	0.976	0.024
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.023	0.977	0.000
H72 Perforation of tympanic membrane	0.023	0.977	0.000
H72.0 Central perforation of tympanic membrane	0.023	0.977	0.000
J45.9 Asthma, unspecified	0.000	0.977	0.023
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.978	0.022
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.022	0.978	0.000
I80 Phlebitis and thrombophlebitis	0.000	0.978	0.022
T40.4 Other synthetic narcotics	0.022	0.978	0.000
H72.8 Other perforations of tympanic membrane	0.021	0.979	0.000
K85 Acute pancreatitis	0.021	0.979	0.000
K83.5 Biliary cyst	0.020	0.979	0.000
K83.2 Perforation of bile duct	0.020	0.979	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.020	0.980	0.000
K83.4 Spasm of sphincter of Oddi	0.020	0.980	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.020	0.980	0.000
J22 Unspecified acute lower respiratory infection	0.000	0.980	0.020
D12.3 Transverse colon	0.000	0.980	0.020
T46 Poisoning by agents primarily affecting the cardiovascular system	0.020	0.980	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.019	0.981	0.000
R01 Cardiac murmurs and other cardiac sounds	0.000	0.981	0.019
T50.9 Other and unspecified drugs, medicaments and biological substances	0.019	0.981	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.019	0.981	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.018	0.982	0.000
K83.3 Fistula of bile duct	0.018	0.982	0.000
K83.9 Disease of biliary tract, unspecified	0.018	0.982	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.018	0.982	0.000
K81 Cholecystitis	0.018	0.982	0.000
T40.6 Other and unspecified narcotics	0.018	0.982	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.982	0.018
D12.9 Anus and anal canal	0.000	0.982	0.018
K87.1 Disorders of pancreas in diseases classified elsewhere	0.017	0.982	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.017	0.982	0.000
D12.1 Appendix	0.000	0.982	0.018
T40.1 Heroin	0.017	0.982	0.000
T50.8 Diagnostic agents	0.017	0.983	0.000
K85.0 Idiopathic acute pancreatitis	0.017	0.983	0.000
T40.5 Cocaine	0.017	0.983	0.000
K85.2 Alcohol-induced acute pancreatitis	0.017	0.983	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.017	0.983	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.016	0.984	0.000
H72.1 Attic perforation of tympanic membrane	0.016	0.984	0.000
T40.2 Other opioids	0.016	0.984	0.000
T47.2 Stimulant laxatives	0.016	0.984	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.016	0.984	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.016	0.984	0.000
T40.8 Lysergide [LSD]	0.016	0.984	0.000
T40.7 Cannabis (derivatives)	0.016	0.984	0.000
T40.3 Methadone	0.016	0.984	0.000
T40.0 Opium	0.016	0.984	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.016	0.984	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.016	0.984	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.016	0.984	0.000
T50.1 Loop [high-ceiling] diuretics	0.016	0.984	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.015	0.984	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.984	0.015
K85.3 Drug-induced acute pancreatitis	0.015	0.985	0.000
K81.0 Acute cholecystitis	0.015	0.985	0.000
N80.0 Endometriosis of uterus	0.015	0.985	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.985	0.015
K83.8 Other specified diseases of biliary tract	0.015	0.985	0.000
T39.0 Salicylates	0.015	0.985	0.000
T46.1 Calcium-channel blockers	0.015	0.985	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.015	0.985	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.015	0.985	0.000
T23.2 Burn of second degree of wrist and hand	0.015	0.985	0.000
T50.7 Analeptics and opioid receptor antagonists	0.015	0.985	0.000
T50.5 Appetite depressants	0.015	0.985	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.015	0.985	0.000
T50.0 Mineralocorticoids and their antagonists	0.015	0.985	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.015	0.985	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.014	0.985	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.014	0.985	0.000
K85.8 Other acute pancreatitis	0.014	0.985	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.014	0.986	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.014	0.986	0.000
T46.7 Peripheral vasodilators	0.014	0.986	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.014	0.986	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.014	0.986	0.000
T47.0 Histamine H(2)-receptor antagonists	0.014	0.986	0.000
T23 Burn and corrosion of wrist and hand	0.014	0.986	0.000
T36 Poisoning by systemic antibiotics	0.014	0.986	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.014	0.986	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.014	0.986	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.014	0.986	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.014	0.986	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.014	0.986	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.014	0.986	0.000
T44.0 Anticholinesterase agents	0.014	0.986	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.014	0.986	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.986	0.014
N83.0 Follicular cyst of ovary	0.014	0.986	0.000
N80.3 Endometriosis of pelvic peritoneum	0.014	0.986	0.000
R01.2 Other cardiac sounds	0.000	0.986	0.014
T47.4 Other laxatives	0.014	0.986	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.014	0.986	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.014	0.986	0.000
T47.7 Emetics	0.014	0.986	0.000
T47.6 Antidiarrhoeal drugs	0.014	0.986	0.000
T47.5 Digestants	0.014	0.986	0.000
T47.3 Saline and osmotic laxatives	0.014	0.986	0.000
K81.8 Other cholecystitis	0.014	0.986	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.013	0.986	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.013	0.987	0.000
K85.1 Biliary acute pancreatitis	0.013	0.987	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.013	0.987	0.000
N80 Endometriosis	0.013	0.987	0.000
T50.4 Drugs affecting uric acid metabolism	0.013	0.987	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.013	0.987	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.013	0.987	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.987	0.013
T42.3 Barbiturates	0.013	0.987	0.000
D12.4 Descending colon	0.000	0.987	0.013
N80.1 Endometriosis of ovary	0.013	0.987	0.000
K76.9 Liver disease, unspecified	0.000	0.988	0.012
D25 Leiomyoma of uterus	0.012	0.988	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.012	0.988	0.000
E00-E07 Disorders of thyroid gland	0.000	0.988	0.012
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.988	0.012
T23.3 Burn of third degree of wrist and hand	0.012	0.988	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.012	0.988	0.000
M45 Ankylosing spondylitis	0.000	0.988	0.012
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.012	0.988	0.000
T23.1 Burn of first degree of wrist and hand	0.012	0.988	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.012	0.988	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.012	0.988	0.000
T42.2 Succinimides and oxazolidinediones	0.012	0.988	0.000
T21 Burn and corrosion of trunk	0.011	0.988	0.000
D25.1 Intramural leiomyoma of uterus	0.011	0.989	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.011	0.989	0.000
T48.4 Expectorants	0.011	0.989	0.000
T48.3 Antitussives	0.011	0.989	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.011	0.989	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.011	0.989	0.000
T48.0 Oxytocic drugs	0.011	0.989	0.000
N80.2 Endometriosis of Fallopian tube	0.011	0.989	0.000
T48.5 Anti-common-cold drugs	0.011	0.989	0.000
T20 Burn and corrosion of head and neck	0.011	0.989	0.000
T41.5 Therapeutic gases	0.011	0.989	0.000
T41.4 Anaesthetic, unspecified	0.011	0.989	0.000
T41.3 Local anaesthetics	0.011	0.989	0.000
T41.2 Other and unspecified general anaesthetics	0.011	0.989	0.000
T41.1 Intravenous anaesthetics	0.011	0.989	0.000
T41.0 Inhaled anaesthetics	0.011	0.989	0.000
T39.4 Antirheumatics, not elsewhere classified	0.011	0.989	0.000
T39.2 Pyrazolone derivatives	0.011	0.989	0.000
R45 Symptoms and signs involving emotional state	0.011	0.989	0.000
D25.2 Subserosal leiomyoma of uterus	0.011	0.989	0.000
T42.1 Iminostilbenes	0.011	0.989	0.000
T49.9 Topical agent, unspecified	0.010	0.989	0.000
T49.8 Other topical agents	0.010	0.989	0.000
T49.7 Dental drugs, topically applied	0.010	0.989	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.010	0.989	0.000
T49.5 Ophthalmological drugs and preparations	0.010	0.989	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.010	0.989	0.000
T49.3 Emollients, demulcents and protectants	0.010	0.989	0.000
T49.2 Local astringents and local detergents	0.010	0.989	0.000
T49.1 Antipruritics	0.010	0.989	0.000
K85.9 Acute pancreatitis, unspecified	0.011	0.989	0.000
T23.7 Corrosion of third degree of wrist and hand	0.010	0.989	0.000
T23.6 Corrosion of second degree of wrist and hand	0.010	0.989	0.000
T23.5 Corrosion of first degree of wrist and hand	0.010	0.989	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.010	0.989	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.010	0.989	0.000
T36.9 Systemic antibiotic, unspecified	0.010	0.989	0.000
T36.8 Other systemic antibiotics	0.010	0.989	0.000
T36.7 Antifungal antibiotics, systemically used	0.010	0.989	0.000
T36.6 Rifamycins	0.010	0.989	0.000
T36.5 Aminoglycosides	0.010	0.989	0.000
T36.4 Tetracyclines	0.010	0.989	0.000
T36.3 Macrolides	0.010	0.989	0.000
T36.2 Chloramphenicol group	0.010	0.989	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.010	0.989	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.010	0.990	0.000
T37.5 Antiviral drugs	0.010	0.990	0.000
T37.4 Anthelminthics	0.010	0.990	0.000
T37.3 Other antiprotozoal drugs	0.010	0.990	0.000
T37.1 Antimycobacterial drugs	0.010	0.990	0.000
T37.0 Sulphonamides	0.010	0.990	0.000
N80.4 Endometriosis of rectovaginal septum and vagina	0.010	0.990	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.010	0.990	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.990	0.010
T21.3 Burn of third degree of trunk	0.010	0.990	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.010	0.990	0.000
R45.2 Unhappiness	0.010	0.990	0.000
R45.8 Other symptoms and signs involving emotional state	0.010	0.990	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.010	0.990	0.000
K81.1 Chronic cholecystitis	0.010	0.990	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.010	0.990	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.010	0.990	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.990	0.010
J20-J22 Other acute lower respiratory infections	0.000	0.990	0.010
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.010	0.990	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.990	0.010
H72.2 Other marginal perforations of tympanic membrane	0.009	0.990	0.001
T36.0 Penicillins	0.010	0.990	0.000
T21.0 Burn of unspecified degree of trunk	0.010	0.990	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.010	0.990	0.000
R45.6 Physical violence	0.010	0.990	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.009	0.990	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.009	0.990	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.009	0.990	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.009	0.990	0.000
R45.4 Irritability and anger	0.009	0.990	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.009	0.990	0.000
N80.5 Endometriosis of intestine	0.009	0.991	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.009	0.991	0.000
T20.3 Burn of third degree of head and neck	0.009	0.991	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.991	0.009
N80.6 Endometriosis in cutaneous scar	0.009	0.991	0.000
R45.1 Restlessness and agitation	0.009	0.991	0.000
T25 Burn and corrosion of ankle and foot	0.009	0.991	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.991	0.009
E00 Congenital iodine-deficiency syndrome	0.000	0.991	0.009
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.991	0.009
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.991	0.009
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.991	0.009
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.991	0.009
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.991	0.009
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.991	0.009
D12.8 Rectum	0.000	0.991	0.009
T20.2 Burn of second degree of head and neck	0.009	0.991	0.000
T42.0 Hydantoin derivatives	0.008	0.991	0.000
R45.5 Hostility	0.008	0.991	0.000
T21.7 Corrosion of third degree of trunk	0.008	0.991	0.000
T21.6 Corrosion of second degree of trunk	0.008	0.991	0.000
T21.5 Corrosion of first degree of trunk	0.008	0.991	0.000
T21.4 Corrosion of unspecified degree of trunk	0.008	0.991	0.000
T20.0 Burn of unspecified degree of head and neck	0.008	0.992	0.000
T21.2 Burn of second degree of trunk	0.008	0.992	0.000
T20.7 Corrosion of third degree of head and neck	0.008	0.992	0.000
T20.6 Corrosion of second degree of head and neck	0.008	0.992	0.000
T20.5 Corrosion of first degree of head and neck	0.008	0.992	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.008	0.992	0.000
T20.1 Burn of first degree of head and neck	0.008	0.992	0.000
K82 Other diseases of gallbladder	0.008	0.992	0.000
R45.3 Demoralisation and apathy	0.008	0.992	0.000
E07 Other disorders of thyroid	0.000	0.992	0.008
J20 Acute bronchitis	0.000	0.992	0.008
R45.7 State of emotional shock and stress, unspecified	0.008	0.992	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.008	0.992	0.000
T38.1 Thyroid hormones and substitutes	0.007	0.992	0.000
J21 Acute bronchiolitis	0.000	0.992	0.007
R45.0 Nervousness	0.007	0.992	0.000
T38.9 Other and unspecified hormone antagonists	0.007	0.992	0.000
T38.7 Androgens and anabolic congeners	0.007	0.992	0.000
T38.5 Other oestrogens and progestogens	0.007	0.992	0.000
T38.4 Oral contraceptives	0.007	0.992	0.000
T38.2 Antithyroid drugs	0.007	0.992	0.000
T38.0 Glucocorticoids and synthetic analogues	0.007	0.992	0.000
R01.0 Benign and innocent cardiac murmurs	0.000	0.992	0.007
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.007	0.993	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.007	0.993	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
T25.2 Burn of second degree of ankle and foot	0.007	0.993	0.000
K82.3 Fistula of gallbladder	0.007	0.993	0.000
T21.1 Burn of first degree of trunk	0.007	0.993	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.007	0.993	0.000
R46.2 Strange and inexplicable behaviour	0.007	0.993	0.000
T42.4 Benzodiazepines	0.007	0.993	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
J92.9 Pleural plaque without asbestos	0.000	0.993	0.007
E07.8 Other specified disorders of thyroid	0.000	0.993	0.007
R46 Symptoms and signs involving appearance and behaviour	0.007	0.993	0.000
T39.1 4-Aminophenol derivatives	0.007	0.993	0.000
E06 Thyroiditis	0.000	0.993	0.007
T25.7 Corrosion of third degree of ankle and foot	0.006	0.993	0.000
T25.6 Corrosion of second degree of ankle and foot	0.006	0.993	0.000
T25.5 Corrosion of first degree of ankle and foot	0.006	0.993	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.006	0.993	0.000
T25.1 Burn of first degree of ankle and foot	0.006	0.993	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.993	0.006
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.993	0.006
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.993	0.006
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.993	0.006
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.993	0.006
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.993	0.006
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.993	0.006
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.993	0.006
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.007	0.993	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.993	0.007
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.006	0.993	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.006	0.993	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.994	0.006
J20.9 Acute bronchitis, unspecified	0.000	0.994	0.006
T25.3 Burn of third degree of ankle and foot	0.006	0.994	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.006	0.994	0.000
N80.8 Other endometriosis	0.006	0.994	0.000
K82.9 Disease of gallbladder, unspecified	0.006	0.994	0.000
E07.1 Dyshormogenetic goitre	0.000	0.994	0.006
E07.0 Hypersecretion of calcitonin	0.000	0.994	0.006
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.000	0.994	0.006
R44 Other symptoms and signs involving general sensations and perceptions	0.006	0.994	0.000
J20.7 Acute bronchitis due to echovirus	0.000	0.994	0.006
J20.6 Acute bronchitis due to rhinovirus	0.000	0.994	0.006
J20.5 Acute bronchitis due to respiratory syncytial virus	0.000	0.994	0.006
J20.4 Acute bronchitis due to parainfluenza virus	0.000	0.994	0.006
J20.3 Acute bronchitis due to coxsackie virus	0.000	0.994	0.006
J20.2 Acute bronchitis due to streptococcus	0.000	0.994	0.006
J20.1 Acute bronchitis due to Haemophilus influenzae	0.000	0.994	0.006
J20.0 Acute bronchitis due to Mycoplasma pneumoniae	0.000	0.994	0.006
J20.8 Acute bronchitis due to other specified organisms	0.000	0.994	0.006
J21.9 Acute bronchiolitis, unspecified	0.000	0.994	0.006
K82.0 Obstruction of gallbladder	0.006	0.994	0.000
J21.8 Acute bronchiolitis due to other specified organisms	0.000	0.994	0.006
J21.1 Acute bronchiolitis due to human metapneumovirus	0.000	0.994	0.006
J21.0 Acute bronchiolitis due to respiratory syncytial virus	0.000	0.994	0.006
R42 Dizziness and giddiness	0.006	0.994	0.000
E06.3 Autoimmune thyroiditis	0.000	0.994	0.006
T25.0 Burn of unspecified degree of ankle and foot	0.005	0.994	0.000
R46.4 Slowness and poor responsiveness	0.006	0.994	0.000
R44.0 Auditory hallucinations	0.006	0.994	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.005	0.995	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.995	0.005
B37.3 Candidiasis of vulva and vagina	0.000	0.995	0.005
J45 Asthma	0.000	0.995	0.005
J92 Pleural plaque	0.000	0.995	0.005
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.995	0.005
R46.0 Very low level of personal hygiene	0.005	0.995	0.000
N63 Unspecified lump in breast	0.000	0.995	0.005
T93.0 Sequelae of open wound of lower limb	0.000	0.995	0.005
K82.2 Perforation of gallbladder	0.005	0.995	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.995	0.005
J92.0 Pleural plaque with presence of asbestos	0.000	0.995	0.005
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.005	0.995	0.000
R46.6 Undue concern and preoccupation with stressful events	0.005	0.995	0.000
R46.5 Suspiciousness and marked evasiveness	0.005	0.995	0.000
R46.3 Overactivity	0.005	0.995	0.000
R46.1 Bizarre personal appearance	0.005	0.995	0.000
E06.4 Drug-induced thyroiditis	0.000	0.995	0.005
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.995	0.005
E06.0 Acute thyroiditis	0.000	0.995	0.005
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.995	0.005
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.995	0.005
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.995	0.005
T93 Sequelae of injuries of lower limb	0.000	0.995	0.005
K82.1 Hydrops of gallbladder	0.005	0.995	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.005	0.995	0.000
T45.8 Other primarily systemic and haematological agents	0.005	0.995	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.995	0.000
T45.6 Fibrinolysis-affecting drugs	0.005	0.995	0.000
T45.4 Iron and its compounds	0.005	0.995	0.000
T45.3 Enzymes, not elsewhere classified	0.005	0.995	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.005	0.995	0.000
E06.1 Subacute thyroiditis	0.000	0.995	0.005
K86 Other diseases of pancreas	0.005	0.995	0.000
K81.9 Cholecystitis, unspecified	0.005	0.995	0.000
R44.1 Visual hallucinations	0.005	0.995	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.995	0.005
D21.2 Connective and other soft tissue of lower limb, including hip	0.005	0.995	0.000
G82.2 Paraplegia, unspecified	0.000	0.995	0.005
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.995	0.005
J45.8 Mixed asthma	0.000	0.995	0.005
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.000	0.995	0.004
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.000	0.995	0.004
K82.4 Cholesterolosis of gallbladder	0.005	0.995	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
R43 Disturbances of smell and taste	0.004	0.995	0.000
Z99.8 Dependence on other enabling machines and devices	0.000	0.995	0.005
K65.8 Other peritonitis	0.005	0.995	0.000
E06.5 Other chronic thyroiditis	0.000	0.996	0.004
I74 Arterial embolism and thrombosis	0.000	0.996	0.004
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.996	0.004
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.000	0.996	0.004
T45.2 Vitamins, not elsewhere classified	0.004	0.996	0.000
I86.8 Varicose veins of other specified sites	0.000	0.996	0.004
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.004	0.996	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.004	0.996	0.000
C32.1 Supraglottis	0.000	0.996	0.004
T45.5 Anticoagulants	0.004	0.996	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.996	0.001
E04 Other non-toxic goitre	0.000	0.996	0.004
T43.9 Psychotropic drug, unspecified	0.004	0.996	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.996	0.004
C34.0 Main bronchus	0.000	0.996	0.004
J45.1 Nonallergic asthma	0.000	0.996	0.004
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.996	0.004
C32.9 Larynx, unspecified	0.000	0.996	0.004
E05.5 Thyroid crisis or storm	0.000	0.996	0.004
E05.4 Thyrotoxicosis factitia	0.000	0.996	0.004
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.996	0.004
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.996	0.004
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.996	0.004
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.996	0.004
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.996	0.004
D12.6 Colon, unspecified	0.000	0.996	0.004
R44.2 Other hallucinations	0.004	0.996	0.000
I86 Varicose veins of other sites	0.000	0.996	0.004
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.996	0.004
T93.1 Sequelae of fracture of femur	0.000	0.996	0.004
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
C32 Malignant neoplasm of larynx	0.000	0.996	0.004
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.996	0.004
K86.3 Pseudocyst of pancreas	0.004	0.996	0.000
R43.0 Anosmia	0.003	0.996	0.000
I86.4 Gastric varices	0.000	0.996	0.004
S82.2 Fracture of shaft of tibia	0.000	0.996	0.004
T43.8 Other psychotropic drugs, not elsewhere classified	0.003	0.996	0.000
H69 Other disorders of Eustachian tube	0.000	0.996	0.003
E04.1 Non-toxic single thyroid nodule	0.000	0.996	0.004
C92.1 Chronic myeloid leukaemia	0.000	0.997	0.003
M79.19 Myalgia (Site unspecified)	0.000	0.997	0.003
H69.8 Other specified disorders of Eustachian tube	0.000	0.997	0.003
R43.1 Parosmia	0.003	0.997	0.000
I86.2 Pelvic varices	0.000	0.997	0.003
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.997	0.003
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.997	0.003
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
G95.8 Other specified diseases of spinal cord	0.000	0.997	0.003
M86.9 Osteomyelitis, unspecified	0.000	0.997	0.003
R43.8 Other and unspecified disturbances of smell and taste	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.997	0.003
K86.8 Other specified diseases of pancreas	0.003	0.997	0.000
R43.2 Parageusia	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.997	0.003
K86.0 Alcohol-induced chronic pancreatitis	0.003	0.997	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.997	0.003
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.997	0.003
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
N85.1 Endometrial adenomatous hyperplasia	0.000	0.997	0.003
E04.8 Other specified non-toxic goitre	0.000	0.997	0.003
R94.5 Abnormal results of liver function studies	0.000	0.997	0.003
E04.0 Non-toxic diffuse goitre	0.000	0.997	0.003
I86.3 Vulval varices	0.000	0.997	0.003
Y45.2 Propionic acid derivatives	0.000	0.997	0.003
C60.9 Penis, unspecified	0.000	0.997	0.003
C92.0 Acute myeloid leukaemia	0.000	0.997	0.003
E05.8 Other thyrotoxicosis	0.000	0.997	0.003
C92 Myeloid leukaemia	0.000	0.997	0.003
S82.21 Fracture of shaft of tibia (open)	0.000	0.997	0.003
K11.2 Sialoadenitis	0.000	0.997	0.003
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.997	0.003
E06.9 Thyroiditis, unspecified	0.001	0.997	0.002
Y45.0 Opioids and related analgesics	0.000	0.997	0.003
I86.0 Sublingual varices	0.000	0.997	0.003
R40 Somnolence, stupor and coma	0.003	0.997	0.000
G82.1 Spastic paraplegia	0.000	0.997	0.003
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.997	0.003
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.997	0.003
C32.8 Overlapping lesion of larynx	0.000	0.997	0.003
C32.3 Laryngeal cartilage	0.000	0.997	0.003
C32.2 Subglottis	0.000	0.997	0.003
I86.1 Scrotal varices	0.000	0.997	0.003
C32.0 Glottis	0.000	0.997	0.003
I74.8 Embolism and thrombosis of other arteries	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations