TreeWAS – Variant ID: rs174534

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.2 Calculus of gallbladder without cholecystitis	0.943	0.057	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.307	0.693
K80 Cholelithiasis	0.515	0.485	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.484	0.516	0.000
K80.4 Calculus of bile duct with cholecystitis	0.433	0.567	0.000
K80.3 Calculus of bile duct with cholangitis	0.369	0.631	0.000
E03 Other hypothyroidism	0.000	0.648	0.352
K80.0 Calculus of gallbladder with acute cholecystitis	0.344	0.656	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.727	0.272
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.265	0.735	0.000
K80.8 Other cholelithiasis	0.258	0.742	0.000
E03.5 Myxoedema coma	0.000	0.747	0.252
E03.4 Atrophy of thyroid (acquired)	0.000	0.747	0.252
E03.3 Postinfectious hypothyroidism	0.000	0.747	0.252
E03.8 Other specified hypothyroidism	0.000	0.748	0.252
E03.1 Congenital hypothyroidism without goitre	0.000	0.751	0.249
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.765	0.235
K80.1 Calculus of gallbladder with other cholecystitis	0.158	0.842	0.000
E00-E07 Disorders of thyroid gland	0.000	0.899	0.101
K63.5 Polyp of colon	0.000	0.910	0.090
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.917	0.083
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.924	0.076
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.927	0.073
E00 Congenital iodine-deficiency syndrome	0.000	0.927	0.073
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.928	0.072
E07 Other disorders of thyroid	0.000	0.928	0.072
E07.8 Other specified disorders of thyroid	0.000	0.938	0.062
H72.9 Perforation of tympanic membrane, unspecified	0.062	0.938	0.000
E05.5 Thyroid crisis or storm	0.000	0.945	0.055
E05.4 Thyrotoxicosis factitia	0.000	0.945	0.055
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.945	0.055
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.945	0.055
H72 Perforation of tympanic membrane	0.053	0.947	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.947	0.052
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.947	0.052
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.947	0.052
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.947	0.052
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.947	0.052
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.947	0.052
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.947	0.052
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.947	0.052
E07.1 Dyshormogenetic goitre	0.000	0.948	0.052
E07.0 Hypersecretion of calcitonin	0.000	0.948	0.052
H72.0 Central perforation of tympanic membrane	0.052	0.948	0.000
E04 Other non-toxic goitre	0.000	0.950	0.050
E05.8 Other thyrotoxicosis	0.000	0.953	0.046
E06 Thyroiditis	0.001	0.954	0.045
H72.8 Other perforations of tympanic membrane	0.045	0.955	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.955	0.045
E04.1 Non-toxic single thyroid nodule	0.000	0.955	0.045
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.960	0.039
E04.0 Non-toxic diffuse goitre	0.000	0.963	0.037
E04.8 Other specified non-toxic goitre	0.000	0.964	0.036
D12.5 Sigmoid colon	0.000	0.964	0.036
H72.1 Attic perforation of tympanic membrane	0.036	0.964	0.000
J22 Unspecified acute lower respiratory infection	0.000	0.966	0.034
E06.3 Autoimmune thyroiditis	0.000	0.967	0.033
E06.4 Drug-induced thyroiditis	0.001	0.967	0.032
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.967	0.032
E06.0 Acute thyroiditis	0.001	0.967	0.032
E06.5 Other chronic thyroiditis	0.001	0.968	0.031
E06.1 Subacute thyroiditis	0.001	0.969	0.031
N63 Unspecified lump in breast	0.000	0.971	0.029
T23 Burn and corrosion of wrist and hand	0.029	0.971	0.000
T23.2 Burn of second degree of wrist and hand	0.028	0.972	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.027	0.973	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.973	0.027
T21 Burn and corrosion of trunk	0.027	0.973	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.026	0.974	0.000
T21.3 Burn of third degree of trunk	0.025	0.975	0.000
T23.3 Burn of third degree of wrist and hand	0.024	0.976	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.023	0.977	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.023	0.977	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.022	0.977	0.000
T21.0 Burn of unspecified degree of trunk	0.022	0.977	0.000
T23.1 Burn of first degree of wrist and hand	0.022	0.978	0.000
H72.2 Other marginal perforations of tympanic membrane	0.021	0.978	0.001
T20 Burn and corrosion of head and neck	0.021	0.979	0.000
T21.2 Burn of second degree of trunk	0.021	0.979	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.979	0.021
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.979	0.021
T23.7 Corrosion of third degree of wrist and hand	0.021	0.979	0.000
T23.6 Corrosion of second degree of wrist and hand	0.021	0.979	0.000
T23.5 Corrosion of first degree of wrist and hand	0.021	0.979	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.021	0.979	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.020	0.980	0.000
T21.7 Corrosion of third degree of trunk	0.019	0.981	0.000
T21.6 Corrosion of second degree of trunk	0.019	0.981	0.000
T21.5 Corrosion of first degree of trunk	0.019	0.981	0.000
T21.4 Corrosion of unspecified degree of trunk	0.019	0.981	0.000
T21.1 Burn of first degree of trunk	0.019	0.981	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.019	0.981	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.018	0.981	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.018	0.981	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.018	0.981	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.018	0.981	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.018	0.981	0.000
H60-H62 Diseases of external ear	0.018	0.982	0.000
T25 Burn and corrosion of ankle and foot	0.018	0.982	0.000
H61 Other disorders of external ear	0.018	0.982	0.000
T20.3 Burn of third degree of head and neck	0.018	0.982	0.000
J33.0 Polyp of nasal cavity	0.000	0.982	0.018
H60 Otitis externa	0.017	0.983	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.017	0.983	0.000
H61.3 Acquired stenosis of external ear canal	0.017	0.983	0.000
Chapter VIII Diseases of the ear and mastoid process	0.017	0.983	0.000
H65-H75 Diseases of middle ear and mastoid	0.016	0.984	0.000
D12.2 Ascending colon	0.000	0.984	0.016
H60.9 Otitis externa, unspecified	0.016	0.984	0.000
T20.2 Burn of second degree of head and neck	0.016	0.984	0.000
R45 Symptoms and signs involving emotional state	0.016	0.984	0.000
R45.8 Other symptoms and signs involving emotional state	0.016	0.984	0.000
H61.9 Disorder of external ear, unspecified	0.016	0.984	0.000
H61.2 Impacted cerumen	0.016	0.984	0.000
H80-H83 Diseases of inner ear	0.016	0.984	0.000
T20.7 Corrosion of third degree of head and neck	0.015	0.984	0.000
T20.6 Corrosion of second degree of head and neck	0.015	0.984	0.000
T20.5 Corrosion of first degree of head and neck	0.015	0.984	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.015	0.984	0.000
T20.0 Burn of unspecified degree of head and neck	0.015	0.984	0.000
H60.1 Cellulitis of external ear	0.016	0.984	0.000
R45.2 Unhappiness	0.016	0.984	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.015	0.985	0.000
K81 Cholecystitis	0.015	0.985	0.000
H66.9 Otitis media, unspecified	0.015	0.985	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.015	0.985	0.000
J20-J22 Other acute lower respiratory infections	0.000	0.985	0.015
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.015	0.985	0.000
H61.1 Non-infective disorders of pinna	0.015	0.985	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.985	0.015
H81 Disorders of vestibular function	0.015	0.985	0.000
H66 Suppurative and unspecified otitis media	0.015	0.985	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.014	0.985	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.014	0.985	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.014	0.985	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.014	0.985	0.000
K76.9 Liver disease, unspecified	0.000	0.985	0.015
R45.6 Physical violence	0.014	0.986	0.000
H92.1 Otorrhoea	0.014	0.986	0.000
H83 Other diseases of inner ear	0.014	0.986	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.014	0.986	0.000
R45.1 Restlessness and agitation	0.014	0.986	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.014	0.986	0.000
D12.0 Caecum	0.000	0.986	0.014
K81.0 Acute cholecystitis	0.014	0.986	0.000
T20.1 Burn of first degree of head and neck	0.014	0.986	0.000
T25.2 Burn of second degree of ankle and foot	0.013	0.986	0.000
H60.0 Abscess of external ear	0.013	0.986	0.000
H81.1 Benign paroxysmal vertigo	0.013	0.987	0.000
H83.0 Labyrinthitis	0.013	0.987	0.000
T25.3 Burn of third degree of ankle and foot	0.013	0.987	0.000
T25.7 Corrosion of third degree of ankle and foot	0.013	0.987	0.000
T25.6 Corrosion of second degree of ankle and foot	0.013	0.987	0.000
T25.5 Corrosion of first degree of ankle and foot	0.013	0.987	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.013	0.987	0.000
T25.1 Burn of first degree of ankle and foot	0.013	0.987	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.013	0.987	0.000
E14.3 With ophthalmic complications	0.000	0.987	0.013
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.013	0.987	0.000
E06.9 Thyroiditis, unspecified	0.002	0.987	0.011
R45.5 Hostility	0.013	0.987	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.013	0.987	0.000
H60.4 Cholesteatoma of external ear	0.013	0.987	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.013	0.987	0.000
H60.2 Malignant otitis externa	0.013	0.987	0.000
H92 Otalgia and effusion of ear	0.013	0.987	0.000
K81.1 Chronic cholecystitis	0.013	0.987	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.013	0.987	0.000
R45.4 Irritability and anger	0.012	0.987	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.012	0.988	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.988	0.012
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.012	0.988	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.012	0.988	0.000
H81.3 Other peripheral vertigo	0.012	0.988	0.000
J33 Nasal polyp	0.000	0.988	0.012
H60.8 Other otitis externa	0.012	0.988	0.000
D12.3 Transverse colon	0.000	0.988	0.012
H81.8 Other disorders of vestibular function	0.012	0.988	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.012	0.988	0.000
H68 Eustachian salpingitis and obstruction	0.012	0.988	0.000
H67 Otitis media in diseases classified elsewhere	0.012	0.988	0.000
E14 Unspecified diabetes mellitus	0.000	0.988	0.012
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.012	0.988	0.000
J33.9 Nasal polyp, unspecified	0.000	0.988	0.012
R45.3 Demoralisation and apathy	0.012	0.988	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.988	0.012
T40.4 Other synthetic narcotics	0.012	0.988	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.012	0.988	0.000
H66.4 Suppurative otitis media, unspecified	0.012	0.988	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.988	0.012
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.988	0.012
E10-E14 Diabetes mellitus	0.000	0.988	0.012
H83.8 Other specified diseases of inner ear	0.011	0.988	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.012	0.988	0.000
H60.5 Acute otitis externa, non-infective	0.011	0.988	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.011	0.988	0.000
H90-H95 Other disorders of ear	0.011	0.989	0.000
H81.0 Meniere's disease	0.011	0.989	0.000
H61.8 Other specified disorders of external ear	0.011	0.989	0.000
K85 Acute pancreatitis	0.011	0.989	0.000
H00.1 Chalazion	0.000	0.989	0.011
J20 Acute bronchitis	0.000	0.989	0.011
J21 Acute bronchiolitis	0.000	0.989	0.011
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.011	0.989	0.000
R45.7 State of emotional shock and stress, unspecified	0.011	0.989	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.011	0.989	0.000
D12.7 Rectosigmoid junction	0.000	0.989	0.011
T40.6 Other and unspecified narcotics	0.011	0.989	0.000
T40.1 Heroin	0.011	0.989	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.011	0.989	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.011	0.989	0.000
H81.4 Vertigo of central origin	0.011	0.989	0.000
T40.2 Other opioids	0.011	0.989	0.000
E14.1 With ketoacidosis	0.000	0.989	0.011
R45.0 Nervousness	0.011	0.989	0.000
E10.2 With renal complications	0.000	0.989	0.011
H70 Mastoiditis and related conditions	0.010	0.989	0.000
H81.9 Disorder of vestibular function, unspecified	0.010	0.990	0.000
N80.1 Endometriosis of ovary	0.010	0.990	0.000
T40.5 Cocaine	0.010	0.990	0.000
T50.8 Diagnostic agents	0.010	0.990	0.000
H83.2 Labyrinthine dysfunction	0.010	0.990	0.000
H83.1 Labyrinthine fistula	0.010	0.990	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.010	0.990	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.010	0.990	0.000
D12.1 Appendix	0.000	0.990	0.010
H62.8 Other disorders of external ear in diseases classified elsewhere	0.010	0.990	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.010	0.990	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.010	0.990	0.000
H62.2 Otitis externa in mycoses	0.010	0.990	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.010	0.990	0.000
H92.0 Otalgia	0.010	0.990	0.000
E10.4 With neurological complications	0.000	0.990	0.010
T47.1 Other antacids and anti-gastric-secretion drugs	0.010	0.990	0.000
T47.2 Stimulant laxatives	0.010	0.990	0.000
E14.5 With peripheral circulatory complications	0.000	0.990	0.010
K81.8 Other cholecystitis	0.010	0.990	0.000
N80.3 Endometriosis of pelvic peritoneum	0.010	0.990	0.000
H83.3 Noise effects on inner ear	0.010	0.990	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.010	0.990	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.010	0.990	0.000
E10.3 With ophthalmic complications	0.000	0.990	0.010
N80.0 Endometriosis of uterus	0.010	0.990	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.010	0.990	0.000
K85.0 Idiopathic acute pancreatitis	0.010	0.990	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.010	0.990	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.010	0.990	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.010	0.990	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.010	0.990	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.010	0.990	0.000
T44.0 Anticholinesterase agents	0.010	0.990	0.000
H60.3 Other infective otitis externa	0.010	0.990	0.000
N80 Endometriosis	0.010	0.990	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.010	0.990	0.000
T40.8 Lysergide [LSD]	0.010	0.990	0.000
T40.7 Cannabis (derivatives)	0.010	0.990	0.000
T40.3 Methadone	0.010	0.990	0.000
T40.0 Opium	0.010	0.990	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.010	0.990	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.009	0.990	0.000
E10.8 With unspecified complications	0.000	0.990	0.009
E10.1 With ketoacidosis	0.000	0.991	0.009
T47.0 Histamine H(2)-receptor antagonists	0.009	0.991	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.009	0.991	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.009	0.991	0.000
E14.4 With neurological complications	0.000	0.991	0.009
T41 Poisoning by anaesthetics and therapeutic gases	0.009	0.991	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.009	0.991	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.009	0.991	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.009	0.991	0.000
T46.7 Peripheral vasodilators	0.009	0.991	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.009	0.991	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.009	0.991	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.009	0.991	0.000
E10.7 With multiple complications	0.000	0.991	0.009
N80.2 Endometriosis of Fallopian tube	0.009	0.991	0.000
T50.7 Analeptics and opioid receptor antagonists	0.009	0.991	0.000
T50.5 Appetite depressants	0.009	0.991	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.009	0.991	0.000
T50.1 Loop [high-ceiling] diuretics	0.009	0.991	0.000
T50.0 Mineralocorticoids and their antagonists	0.009	0.991	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.009	0.991	0.000
H70.8 Other mastoiditis and related conditions	0.009	0.991	0.000
T46.1 Calcium-channel blockers	0.009	0.991	0.000
T36 Poisoning by systemic antibiotics	0.009	0.991	0.000
H83.9 Disease of inner ear, unspecified	0.009	0.991	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.009	0.991	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.009	0.991	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.009	0.991	0.000
H68.1 Obstruction of Eustachian tube	0.009	0.991	0.000
H68.0 Eustachian salpingitis	0.009	0.991	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.009	0.991	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.009	0.991	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.991	0.009
H66.0 Acute suppurative otitis media	0.009	0.991	0.000
H73 Other disorders of tympanic membrane	0.009	0.991	0.000
E10.5 With peripheral circulatory complications	0.000	0.991	0.009
E14.7 With multiple complications	0.000	0.991	0.009
E14.0 With coma	0.000	0.991	0.009
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.009	0.991	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.009	0.991	0.000
T47.7 Emetics	0.009	0.991	0.000
T47.6 Antidiarrhoeal drugs	0.009	0.991	0.000
T47.5 Digestants	0.009	0.991	0.000
T47.4 Other laxatives	0.009	0.991	0.000
T47.3 Saline and osmotic laxatives	0.009	0.991	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.991	0.009
K85.2 Alcohol-induced acute pancreatitis	0.009	0.991	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.009	0.991	0.000
J33.1 Polypoid sinus degeneration	0.000	0.991	0.009
H65.4 Other chronic nonsuppurative otitis media	0.009	0.991	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.009	0.991	0.000
J20.9 Acute bronchitis, unspecified	0.000	0.991	0.009
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.991	0.009
E12 Malnutrition-related diabetes mellitus	0.000	0.991	0.008
E10.6 With other specified complications	0.000	0.991	0.008
J33.8 Other polyp of sinus	0.000	0.991	0.009
H65 Nonsuppurative otitis media	0.008	0.991	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.008	0.992	0.000
J21.9 Acute bronchiolitis, unspecified	0.000	0.992	0.008
K85.3 Drug-induced acute pancreatitis	0.008	0.992	0.000
H92.2 Otorrhagia	0.008	0.992	0.000
E14.2 Withrenal complications	0.000	0.992	0.008
J20.7 Acute bronchitis due to echovirus	0.000	0.992	0.008
J20.6 Acute bronchitis due to rhinovirus	0.000	0.992	0.008
J20.5 Acute bronchitis due to respiratory syncytial virus	0.000	0.992	0.008
J20.4 Acute bronchitis due to parainfluenza virus	0.000	0.992	0.008
J20.3 Acute bronchitis due to coxsackie virus	0.000	0.992	0.008
J20.2 Acute bronchitis due to streptococcus	0.000	0.992	0.008
J20.1 Acute bronchitis due to Haemophilus influenzae	0.000	0.992	0.008
J20.0 Acute bronchitis due to Mycoplasma pneumoniae	0.000	0.992	0.008
J21.8 Acute bronchiolitis due to other specified organisms	0.000	0.992	0.008
J21.1 Acute bronchiolitis due to human metapneumovirus	0.000	0.992	0.008
J21.0 Acute bronchiolitis due to respiratory syncytial virus	0.000	0.992	0.008
T46.5 Other antihypertensive drugs, not elsewhere classified	0.008	0.992	0.000
H80 Otosclerosis	0.008	0.992	0.000
K82 Other diseases of gallbladder	0.008	0.992	0.000
H95.1 Other disorders following mastoidectomy	0.008	0.992	0.000
T93.0 Sequelae of open wound of lower limb	0.000	0.992	0.008
T48.6 Antiasthmatics, not elsewhere classified	0.008	0.992	0.000
J20.8 Acute bronchitis due to other specified organisms	0.000	0.992	0.008
H81.2 Vestibular neuronitis	0.008	0.992	0.000
D12.9 Anus and anal canal	0.000	0.992	0.008
H70.2 Petrositis	0.008	0.992	0.000
H70.0 Acute mastoiditis	0.008	0.992	0.000
T93 Sequelae of injuries of lower limb	0.000	0.992	0.008
E10.0 With coma	0.000	0.992	0.008
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.992	0.008
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.008	0.992	0.000
N80.4 Endometriosis of rectovaginal septum and vagina	0.008	0.992	0.000
K85.8 Other acute pancreatitis	0.008	0.992	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.008	0.992	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.008	0.992	0.000
T50.4 Drugs affecting uric acid metabolism	0.007	0.992	0.000
E14.8 With unspecified complications	0.000	0.992	0.007
T42.3 Barbiturates	0.008	0.992	0.000
T48.5 Anti-common-cold drugs	0.007	0.992	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.007	0.993	0.000
E50-E64 Other nutritional deficiencies	0.000	0.993	0.007
T39.0 Salicylates	0.007	0.993	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.007	0.993	0.000
T48.4 Expectorants	0.007	0.993	0.000
T48.3 Antitussives	0.007	0.993	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.007	0.993	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.007	0.993	0.000
T48.0 Oxytocic drugs	0.007	0.993	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.993	0.007
E14.6 With other specified complications	0.000	0.993	0.007
H66.3 Other chronic suppurative otitis media	0.007	0.993	0.000
N80.5 Endometriosis of intestine	0.007	0.993	0.000
I74 Arterial embolism and thrombosis	0.000	0.993	0.007
H65.0 Acute serous otitis media	0.007	0.993	0.000
H61.0 Perichondritis of external ear	0.007	0.993	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.993	0.007
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.007	0.993	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.007	0.993	0.000
K82.3 Fistula of gallbladder	0.007	0.993	0.000
T41.5 Therapeutic gases	0.007	0.993	0.000
T41.4 Anaesthetic, unspecified	0.007	0.993	0.000
T41.3 Local anaesthetics	0.007	0.993	0.000
T41.2 Other and unspecified general anaesthetics	0.007	0.993	0.000
T41.1 Intravenous anaesthetics	0.007	0.993	0.000
T41.0 Inhaled anaesthetics	0.007	0.993	0.000
H73.1 Chronic myringitis	0.007	0.993	0.000
T49.9 Topical agent, unspecified	0.007	0.993	0.000
T49.8 Other topical agents	0.007	0.993	0.000
T49.7 Dental drugs, topically applied	0.007	0.993	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.007	0.993	0.000
T49.5 Ophthalmological drugs and preparations	0.007	0.993	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.007	0.993	0.000
T49.3 Emollients, demulcents and protectants	0.007	0.993	0.000
T49.2 Local astringents and local detergents	0.007	0.993	0.000
T49.1 Antipruritics	0.007	0.993	0.000
K81.9 Cholecystitis, unspecified	0.007	0.993	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.007	0.993	0.000
T42.2 Succinimides and oxazolidinediones	0.007	0.993	0.000
E27 Other disorders of adrenal gland	0.000	0.993	0.007
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.007	0.993	0.000
T36.9 Systemic antibiotic, unspecified	0.006	0.993	0.000
T36.8 Other systemic antibiotics	0.006	0.993	0.000
T36.7 Antifungal antibiotics, systemically used	0.006	0.993	0.000
T36.6 Rifamycins	0.006	0.993	0.000
T36.5 Aminoglycosides	0.006	0.993	0.000
T36.4 Tetracyclines	0.006	0.993	0.000
T36.3 Macrolides	0.006	0.993	0.000
T36.2 Chloramphenicol group	0.006	0.993	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.006	0.993	0.000
H69 Other disorders of Eustachian tube	0.005	0.993	0.002
K82.4 Cholesterolosis of gallbladder	0.007	0.993	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.006	0.993	0.000
N80.6 Endometriosis in cutaneous scar	0.007	0.993	0.000
H73.0 Acute myringitis	0.006	0.993	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.993	0.007
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.006	0.993	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.993	0.007
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.006	0.993	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.993	0.007
E23 Hypofunction and other disorders of pituitary gland	0.000	0.993	0.007
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.006	0.993	0.000
T37.5 Antiviral drugs	0.006	0.993	0.000
T37.4 Anthelminthics	0.006	0.993	0.000
T37.3 Other antiprotozoal drugs	0.006	0.993	0.000
T37.1 Antimycobacterial drugs	0.006	0.993	0.000
T37.0 Sulphonamides	0.006	0.993	0.000
H70.1 Chronic mastoiditis	0.006	0.994	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.006	0.994	0.000
E40-E46 Malnutrition	0.000	0.994	0.006
E12.9 Without complications	0.000	0.994	0.006
E12.8 With unspecified complications	0.000	0.994	0.006
E12.7 With multiple complications	0.000	0.994	0.006
E12.6 With other specified complications	0.000	0.994	0.006
E12.5 With peripheral circulatory complications	0.000	0.994	0.006
E12.4 With neurological complications	0.000	0.994	0.006
E12.3 With ophthalmic complications	0.000	0.994	0.006
E12.2 With renal complications	0.000	0.994	0.006
E12.1 With ketoacidosis	0.000	0.994	0.006
E12.0 With coma	0.000	0.994	0.006
G45.4 Transient global amnesia	0.006	0.994	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.006	0.994	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
T36.0 Penicillins	0.006	0.994	0.000
E23.6 Other disorders of pituitary gland	0.000	0.994	0.006
E61 Deficiency of other nutrient elements	0.000	0.994	0.006
K85.1 Biliary acute pancreatitis	0.006	0.994	0.000
H70.9 Mastoiditis, unspecified	0.006	0.994	0.000
H80.8 Other otosclerosis	0.006	0.994	0.000
H80.2 Cochlear otosclerosis	0.006	0.994	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.006	0.994	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.006	0.994	0.000
E23.2 Diabetes insipidus	0.000	0.994	0.006
E20-E35 Disorders of other endocrine glands	0.000	0.994	0.006
W22.9 Unspecified place	0.000	0.994	0.006
M86.9 Osteomyelitis, unspecified	0.000	0.994	0.006
Z29.2 Other prophylactic chemotherapy	0.006	0.994	0.000
T42.1 Iminostilbenes	0.006	0.994	0.000
E58 Dietary calcium deficiency	0.000	0.994	0.006
H00 Hordeolum and chalazion	0.000	0.994	0.006
E78.0 Pure hypercholesterolaemia	0.000	0.994	0.006
E10.9 Without complications	0.000	0.994	0.006
K82.9 Disease of gallbladder, unspecified	0.006	0.994	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.994	0.006
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.994	0.006
E15 Nondiabetic hypoglycaemic coma	0.000	0.994	0.006
T39.4 Antirheumatics, not elsewhere classified	0.006	0.994	0.000
T39.2 Pyrazolone derivatives	0.006	0.994	0.000
Z99.8 Dependence on other enabling machines and devices	0.000	0.994	0.006
H73.9 Disorder of tympanic membrane, unspecified	0.006	0.994	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.994	0.006
H93 Other disorders of ear, not elsewhere classified	0.006	0.994	0.000
E56 Other vitamin deficiencies	0.000	0.994	0.006
E51 Thiamine deficiency	0.000	0.994	0.006
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.006	0.994	0.000
E27.2 Addisonian crisis	0.000	0.994	0.006
T37.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.994	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.006	0.994	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.994	0.005
E63 Other nutritional deficiencies	0.000	0.994	0.005
E50 Vitamin A deficiency	0.000	0.994	0.005
E60 Dietary zinc deficiency	0.000	0.994	0.005
E59 Dietary selenium deficiency	0.000	0.994	0.005
E52 Niacin deficiency [pellagra]	0.000	0.994	0.005
H65.1 Other acute nonsuppurative otitis media	0.005	0.994	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.000	0.994	0.006
D25.9 Leiomyoma of uterus, unspecified	0.006	0.994	0.000
T93.1 Sequelae of fracture of femur	0.000	0.994	0.005
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.994	0.005
K85.9 Acute pancreatitis, unspecified	0.005	0.994	0.000
K82.1 Hydrops of gallbladder	0.005	0.995	0.000
R46.2 Strange and inexplicable behaviour	0.005	0.995	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.005	0.995	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.995	0.005
T42.0 Hydantoin derivatives	0.005	0.995	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.995	0.005
E13 Other specified diabetes mellitus	0.000	0.995	0.005
K82.2 Perforation of gallbladder	0.005	0.995	0.000
K82.0 Obstruction of gallbladder	0.005	0.995	0.000
N85.1 Endometrial adenomatous hyperplasia	0.000	0.995	0.005
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.995	0.005
E61.1 Iron deficiency	0.000	0.995	0.005
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.995	0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations