TreeWAS – Variant ID: rs174545

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.2 Calculus of gallbladder without cholecystitis	0.999	0.001	0.000
J45.9 Asthma, unspecified	0.000	0.226	0.774
J33.0 Polyp of nasal cavity	0.000	0.382	0.618
J33 Nasal polyp	0.000	0.387	0.613
J33.9 Nasal polyp, unspecified	0.000	0.397	0.603
J33.8 Other polyp of sinus	0.000	0.412	0.588
K80 Cholelithiasis	0.559	0.441	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.476	0.524	0.000
K80.4 Calculus of bile duct with cholecystitis	0.475	0.525	0.000
J33.1 Polypoid sinus degeneration	0.000	0.541	0.459
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.428	0.572	0.000
K80.3 Calculus of bile duct with cholangitis	0.401	0.599	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.691	0.309
K80.8 Other cholelithiasis	0.294	0.706	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.288	0.712	0.000
H00.1 Chalazion	0.000	0.741	0.259
K80.1 Calculus of gallbladder with other cholecystitis	0.244	0.756	0.000
N83.2 Other and unspecified ovarian cysts	0.226	0.774	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.209	0.791	0.000
N83.3 Acquired atrophy of ovary and Fallopian tube	0.199	0.801	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.193	0.807	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.191	0.809	0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.168	0.832	0.000
D25.9 Leiomyoma of uterus, unspecified	0.164	0.836	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.153	0.847	0.000
J45 Asthma	0.000	0.848	0.152
N83.7 Haematoma of broad ligament	0.150	0.850	0.000
K83 Other diseases of biliary tract	0.145	0.855	0.000
K83.1 Obstruction of bile duct	0.135	0.865	0.000
K83.0 Cholangitis	0.135	0.865	0.000
N83.6 Haematosalpinx	0.133	0.866	0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.126	0.874	0.000
N83.1 Corpus luteum cyst	0.122	0.878	0.000
E03 Other hypothyroidism	0.000	0.879	0.121
H00 Hordeolum and chalazion	0.000	0.887	0.113
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.110	0.890	0.000
J45.8 Mixed asthma	0.000	0.891	0.109
J45.1 Nonallergic asthma	0.000	0.892	0.108
K83.5 Biliary cyst	0.104	0.896	0.000
K83.2 Perforation of bile duct	0.104	0.896	0.000
K83.4 Spasm of sphincter of Oddi	0.103	0.897	0.000
N83.0 Follicular cyst of ovary	0.098	0.902	0.000
K85 Acute pancreatitis	0.094	0.906	0.000
K83.3 Fistula of bile duct	0.093	0.907	0.000
K83.9 Disease of biliary tract, unspecified	0.091	0.909	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.911	0.089
K81 Cholecystitis	0.089	0.911	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.911	0.089
E03.5 Myxoedema coma	0.000	0.913	0.087
E03.4 Atrophy of thyroid (acquired)	0.000	0.913	0.087
E03.3 Postinfectious hypothyroidism	0.000	0.913	0.087
E03.1 Congenital hypothyroidism without goitre	0.000	0.913	0.087
K83.8 Other specified diseases of biliary tract	0.085	0.915	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.919	0.081
E03.8 Other specified hypothyroidism	0.000	0.920	0.080
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.920	0.080
K87.1 Disorders of pancreas in diseases classified elsewhere	0.079	0.921	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.079	0.921	0.000
K85.2 Alcohol-induced acute pancreatitis	0.076	0.924	0.000
K85.0 Idiopathic acute pancreatitis	0.072	0.928	0.000
K63.5 Polyp of colon	0.000	0.928	0.072
K81.0 Acute cholecystitis	0.071	0.929	0.000
K85.3 Drug-induced acute pancreatitis	0.067	0.933	0.000
K85.8 Other acute pancreatitis	0.066	0.934	0.000
K82 Other diseases of gallbladder	0.064	0.936	0.000
K81.8 Other cholecystitis	0.063	0.936	0.000
K86 Other diseases of pancreas	0.061	0.939	0.000
K81.1 Chronic cholecystitis	0.058	0.942	0.000
K76.9 Liver disease, unspecified	0.000	0.945	0.055
K82.9 Disease of gallbladder, unspecified	0.053	0.947	0.000
K82.3 Fistula of gallbladder	0.053	0.947	0.000
K85.1 Biliary acute pancreatitis	0.053	0.947	0.000
D25 Leiomyoma of uterus	0.050	0.950	0.000
K86.3 Pseudocyst of pancreas	0.049	0.951	0.000
K86.8 Other specified diseases of pancreas	0.047	0.953	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.046	0.954	0.000
K85.9 Acute pancreatitis, unspecified	0.046	0.954	0.000
K82.2 Perforation of gallbladder	0.045	0.955	0.000
D25.1 Intramural leiomyoma of uterus	0.042	0.958	0.000
K82.4 Cholesterolosis of gallbladder	0.042	0.958	0.000
D25.2 Subserosal leiomyoma of uterus	0.038	0.962	0.000
K82.0 Obstruction of gallbladder	0.038	0.962	0.000
D12.5 Sigmoid colon	0.000	0.963	0.037
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.964	0.036
K81.9 Cholecystitis, unspecified	0.036	0.964	0.000
K82.1 Hydrops of gallbladder	0.033	0.967	0.000
K86.1 Other chronic pancreatitis	0.032	0.968	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.969	0.031
D12.2 Ascending colon	0.000	0.971	0.029
J45.0 Predominantly allergic asthma	0.000	0.972	0.028
D12.3 Transverse colon	0.000	0.972	0.028
D12.0 Caecum	0.000	0.973	0.027
D12.7 Rectosigmoid junction	0.000	0.973	0.027
K86.2 Cyst of pancreas	0.026	0.974	0.000
I80 Phlebitis and thrombophlebitis	0.000	0.974	0.026
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.975	0.025
K86.9 Disease of pancreas, unspecified	0.024	0.976	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.976	0.024
D12.1 Appendix	0.000	0.976	0.024
D12.9 Anus and anal canal	0.000	0.978	0.022
R01 Cardiac murmurs and other cardiac sounds	0.000	0.979	0.021
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.979	0.021
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.981	0.019
E00-E07 Disorders of thyroid gland	0.000	0.981	0.019
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.981	0.019
T93 Sequelae of injuries of lower limb	0.000	0.982	0.018
D12.8 Rectum	0.000	0.982	0.018
D12.4 Descending colon	0.000	0.982	0.018
T93.0 Sequelae of open wound of lower limb	0.000	0.983	0.017
T21 Burn and corrosion of trunk	0.017	0.983	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.017	0.983	0.000
T23 Burn and corrosion of wrist and hand	0.017	0.983	0.000
T23.2 Burn of second degree of wrist and hand	0.016	0.984	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.984	0.016
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.016	0.984	0.000
T21.3 Burn of third degree of trunk	0.016	0.984	0.000
R01.2 Other cardiac sounds	0.000	0.984	0.015
T21.0 Burn of unspecified degree of trunk	0.015	0.985	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.985	0.015
E07 Other disorders of thyroid	0.000	0.986	0.014
T20 Burn and corrosion of head and neck	0.014	0.986	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.014	0.986	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.986	0.014
E00 Congenital iodine-deficiency syndrome	0.000	0.986	0.014
T23.3 Burn of third degree of wrist and hand	0.014	0.986	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.014	0.986	0.000
T23.1 Burn of first degree of wrist and hand	0.014	0.986	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.986	0.013
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.986	0.013
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.987	0.013
E07.8 Other specified disorders of thyroid	0.000	0.987	0.013
T21.2 Burn of second degree of trunk	0.013	0.987	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.013	0.987	0.000
T21.7 Corrosion of third degree of trunk	0.012	0.987	0.000
T21.6 Corrosion of second degree of trunk	0.012	0.987	0.000
T21.5 Corrosion of first degree of trunk	0.012	0.987	0.000
T21.4 Corrosion of unspecified degree of trunk	0.012	0.987	0.000
T21.1 Burn of first degree of trunk	0.012	0.987	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.012	0.988	0.000
T23.7 Corrosion of third degree of wrist and hand	0.012	0.988	0.000
T23.6 Corrosion of second degree of wrist and hand	0.012	0.988	0.000
T23.5 Corrosion of first degree of wrist and hand	0.012	0.988	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.012	0.988	0.000
T93.1 Sequelae of fracture of femur	0.000	0.988	0.012
T20.3 Burn of third degree of head and neck	0.012	0.988	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.012	0.988	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.012	0.988	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.012	0.988	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.012	0.988	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.012	0.988	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.988	0.012
K82.8 Other specified diseases of gallbladder	0.012	0.988	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.988	0.012
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.989	0.011
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.989	0.011
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.989	0.011
T23.0 Burn of unspecified degree of wrist and hand	0.011	0.989	0.000
J22 Unspecified acute lower respiratory infection	0.000	0.989	0.011
T25 Burn and corrosion of ankle and foot	0.011	0.989	0.000
T20.2 Burn of second degree of head and neck	0.011	0.989	0.000
T20.1 Burn of first degree of head and neck	0.011	0.989	0.000
E07.1 Dyshormogenetic goitre	0.000	0.989	0.010
E07.0 Hypersecretion of calcitonin	0.000	0.989	0.010
T20.0 Burn of unspecified degree of head and neck	0.011	0.989	0.000
T20.7 Corrosion of third degree of head and neck	0.010	0.989	0.000
T20.6 Corrosion of second degree of head and neck	0.010	0.989	0.000
T20.5 Corrosion of first degree of head and neck	0.010	0.989	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.010	0.989	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.990	0.010
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.990	0.010
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.990	0.010
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.990	0.010
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.990	0.010
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.990	0.010
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.990	0.010
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.990	0.010
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.010	0.990	0.000
E06 Thyroiditis	0.000	0.990	0.010
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.009	0.991	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.009	0.991	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.009	0.991	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.009	0.991	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.009	0.991	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.009	0.991	0.000
E05.5 Thyroid crisis or storm	0.000	0.991	0.009
E05.4 Thyrotoxicosis factitia	0.000	0.991	0.009
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.991	0.009
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.991	0.009
T25.2 Burn of second degree of ankle and foot	0.008	0.991	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.992	0.008
O80.9 Single spontaneous delivery, unspecified	0.000	0.992	0.008
T25.7 Corrosion of third degree of ankle and foot	0.008	0.992	0.000
T25.6 Corrosion of second degree of ankle and foot	0.008	0.992	0.000
T25.5 Corrosion of first degree of ankle and foot	0.008	0.992	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.008	0.992	0.000
T25.1 Burn of first degree of ankle and foot	0.008	0.992	0.000
E06.3 Autoimmune thyroiditis	0.000	0.992	0.008
R51 Headache	0.008	0.992	0.000
T25.3 Burn of third degree of ankle and foot	0.008	0.992	0.000
R01.0 Benign and innocent cardiac murmurs	0.000	0.992	0.008
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.007	0.992	0.000
E05.8 Other thyrotoxicosis	0.000	0.992	0.007
E06.4 Drug-induced thyroiditis	0.000	0.993	0.007
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.993	0.007
E06.0 Acute thyroiditis	0.000	0.993	0.007
D12.6 Colon, unspecified	0.000	0.993	0.007
E06.1 Subacute thyroiditis	0.000	0.993	0.007
H69.8 Other specified disorders of Eustachian tube	0.000	0.993	0.007
H69.9 Eustachian tube disorder, unspecified	0.000	0.993	0.007
T25.0 Burn of unspecified degree of ankle and foot	0.007	0.993	0.000
B37.3 Candidiasis of vulva and vagina	0.000	0.993	0.007
E07.9 Disorder of thyroid, unspecified	0.000	0.993	0.007
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.000	0.993	0.007
K11.2 Sialoadenitis	0.000	0.994	0.006
E06.5 Other chronic thyroiditis	0.001	0.994	0.006
H69 Other disorders of Eustachian tube	0.000	0.994	0.006
I31.3 Pericardial effusion (noninflammatory)	0.000	0.994	0.006
K76 Other diseases of liver	0.000	0.994	0.006
H72.9 Perforation of tympanic membrane, unspecified	0.006	0.994	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.000	0.994	0.006
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.994	0.005
E04 Other non-toxic goitre	0.000	0.994	0.006
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.000	0.994	0.006
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.995	0.005
H05.2 Exophthalmic conditions	0.000	0.995	0.005
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.995	0.005
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.995	0.005
J20-J22 Other acute lower respiratory infections	0.000	0.995	0.005
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.995	0.005
H06.2 Dysthyroid exophthalmos	0.000	0.995	0.005
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.995	0.005
O24 Diabetes mellitus in pregnancy	0.000	0.995	0.005
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.995	0.005
H05 Disorders of orbit	0.000	0.995	0.005
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.995	0.005
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.995	0.005
E04.1 Non-toxic single thyroid nodule	0.000	0.995	0.005
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.995	0.005
H69.0 Patulous Eustachian tube	0.000	0.995	0.005
M45 Ankylosing spondylitis	0.000	0.995	0.005
D21.2 Connective and other soft tissue of lower limb, including hip	0.005	0.995	0.000
K76.1 Chronic passive congestion of liver	0.000	0.995	0.004
E05.9 Thyrotoxicosis, unspecified	0.000	0.995	0.005
S52.00 Fracture of upper end of ulna (closed)	0.000	0.996	0.004
K76.5 Hepatic veno-occlusive disease	0.000	0.996	0.004
K76.4 Peliosis hepatis	0.000	0.996	0.004
K76.3 Infarction of liver	0.000	0.996	0.004
K76.2 Central haemorrhagic necrosis of liver	0.000	0.996	0.004
N80.0 Endometriosis of uterus	0.004	0.996	0.000
K65.8 Other peritonitis	0.004	0.996	0.000
H01 Other inflammation of eyelid	0.000	0.996	0.004
H06.3 Other disorders of orbit in diseases classified elsewhere	0.000	0.996	0.004
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.000	0.996	0.004
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.000	0.996	0.004
E04.8 Other specified non-toxic goitre	0.000	0.996	0.004
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.000	0.996	0.004
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
H03 Disorders of eyelid in diseases classified elsewhere	0.000	0.996	0.004
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.004	0.996	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.996	0.004
H72 Perforation of tympanic membrane	0.004	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
H72.0 Central perforation of tympanic membrane	0.004	0.996	0.000
J21 Acute bronchiolitis	0.000	0.996	0.004
E04.0 Non-toxic diffuse goitre	0.000	0.996	0.004
E06.9 Thyroiditis, unspecified	0.001	0.996	0.003
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.996	0.004
J20 Acute bronchitis	0.000	0.996	0.004
H72.8 Other perforations of tympanic membrane	0.004	0.996	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.996	0.004
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.996	0.004
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.996	0.004
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.996	0.004
T40.4 Other synthetic narcotics	0.004	0.996	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.000	0.996	0.004
H05.3 Deformity of orbit	0.000	0.996	0.004
H05.1 Chronic inflammatory disorders of orbit	0.000	0.996	0.004
I31 Other diseases of pericardium	0.000	0.996	0.004
C25.0 Head of pancreas	0.004	0.996	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.996	0.004
H05.4 Enophthalmos	0.000	0.996	0.004
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.996	0.004
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
H01.0 Blepharitis	0.000	0.996	0.004
H01.9 Inflammation of eyelid, unspecified	0.000	0.996	0.004
H05.9 Disorder of orbit, unspecified	0.000	0.996	0.003
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.996	0.003
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.996	0.003
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.996	0.003
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.996	0.003
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.996	0.003
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.996	0.003
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.004	0.996	0.000
O21.0 Mild hyperemesis gravidarum	0.000	0.996	0.004
E89.0 Postprocedural hypothyroidism	0.000	0.996	0.004
J92.9 Pleural plaque without asbestos	0.000	0.997	0.003
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.997	0.003
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.000	0.997	0.003
J20.9 Acute bronchitis, unspecified	0.000	0.997	0.003
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.997	0.003
H05.8 Other disorders of orbit	0.000	0.997	0.003
T50.8 Diagnostic agents	0.003	0.997	0.000
H01.1 Non-infectious dermatoses of eyelid	0.000	0.997	0.003
J21.8 Acute bronchiolitis due to other specified organisms	0.000	0.997	0.003
J21.1 Acute bronchiolitis due to human metapneumovirus	0.000	0.997	0.003
J21.0 Acute bronchiolitis due to respiratory syncytial virus	0.000	0.997	0.003
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.003	0.997	0.000
H72.1 Attic perforation of tympanic membrane	0.003	0.997	0.000
J20.7 Acute bronchitis due to echovirus	0.000	0.997	0.003
J20.6 Acute bronchitis due to rhinovirus	0.000	0.997	0.003
J20.5 Acute bronchitis due to respiratory syncytial virus	0.000	0.997	0.003
J20.4 Acute bronchitis due to parainfluenza virus	0.000	0.997	0.003
J20.3 Acute bronchitis due to coxsackie virus	0.000	0.997	0.003
J20.2 Acute bronchitis due to streptococcus	0.000	0.997	0.003
J20.1 Acute bronchitis due to Haemophilus influenzae	0.000	0.997	0.003
J20.0 Acute bronchitis due to Mycoplasma pneumoniae	0.000	0.997	0.003
J21.9 Acute bronchiolitis, unspecified	0.000	0.997	0.003
G25.0 Essential tremor	0.003	0.997	0.000
D25.0 Submucous leiomyoma of uterus	0.003	0.997	0.000
T40.1 Heroin	0.003	0.997	0.000
O80 Single spontaneous delivery	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
O21 Excessive vomiting in pregnancy	0.000	0.997	0.003
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.000	0.997	0.003
I31.8 Other specified diseases of pericardium	0.000	0.997	0.003
I31.2 Haemopericardium, not elsewhere classified	0.000	0.997	0.003
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
O80.8 Other single spontaneous delivery	0.000	0.997	0.003
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
S32.0 Fracture of lumbar vertebra	0.000	0.997	0.003
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
T40.5 Cocaine	0.003	0.997	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.000	0.997	0.003
T40.6 Other and unspecified narcotics	0.003	0.997	0.000
E10.4 With neurological complications	0.000	0.997	0.003
Z29.2 Other prophylactic chemotherapy	0.003	0.997	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.997	0.003
I31.0 Chronic adhesive pericarditis	0.000	0.997	0.003
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
T44.0 Anticholinesterase agents	0.003	0.997	0.000
J20.8 Acute bronchitis due to other specified organisms	0.000	0.997	0.003
I31.1 Chronic constrictive pericarditis	0.000	0.997	0.003
T50.1 Loop [high-ceiling] diuretics	0.003	0.997	0.000
C25.9 Pancreas, unspecified	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.997	0.000
T40.8 Lysergide [LSD]	0.003	0.997	0.000
T40.7 Cannabis (derivatives)	0.003	0.997	0.000
T40.3 Methadone	0.003	0.997	0.000
T40.0 Opium	0.003	0.997	0.000
G45.4 Transient global amnesia	0.003	0.997	0.000
K76.7 Hepatorenal syndrome	0.000	0.997	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.997	0.003
F45.8 Other somatoform disorders	0.000	0.997	0.003
Y45.2 Propionic acid derivatives	0.000	0.997	0.003
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
E10.1 With ketoacidosis	0.000	0.997	0.003
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
I74 Arterial embolism and thrombosis	0.000	0.997	0.003
T47.2 Stimulant laxatives	0.003	0.997	0.000
C25 Malignant neoplasm of pancreas	0.003	0.997	0.000
O21.2 Late vomiting of pregnancy	0.000	0.997	0.003
E89.4 Postprocedural ovarian failure	0.000	0.997	0.003
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.997	0.003
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.997	0.003
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.997	0.003
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.997	0.003
T40.2 Other opioids	0.003	0.997	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.997	0.002
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.997	0.002
E89.5 Postprocedural testicular hypofunction	0.000	0.997	0.002
E89.1 Postprocedural hypoinsulinaemia	0.000	0.997	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.997	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.003	0.997	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.997	0.003
E10.3 With ophthalmic complications	0.000	0.997	0.003
H01.8 Other specified inflammation of eyelid	0.000	0.997	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.997	0.000
O21.8 Other vomiting complicating pregnancy	0.000	0.997	0.002
C25.2 Tail of pancreas	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
O80.1 Spontaneous breech delivery	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.998	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.998	0.002
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
E10.8 With unspecified complications	0.000	0.998	0.002
J04.0 Acute laryngitis	0.002	0.998	0.000
L30.9 Dermatitis, unspecified	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.002
C60.9 Penis, unspecified	0.000	0.998	0.002
C92.1 Chronic myeloid leukaemia	0.000	0.998	0.002
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
E10.2 With renal complications	0.000	0.998	0.002
H72.2 Other marginal perforations of tympanic membrane	0.002	0.998	0.000
C25.1 Body of pancreas	0.002	0.998	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.002	0.998	0.000
C25.4 Endocrine pancreas	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.998	0.002
E23.2 Diabetes insipidus	0.000	0.998	0.002
H61.2 Impacted cerumen	0.002	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
O21.9 Vomiting of pregnancy, unspecified	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
E10.7 With multiple complications	0.000	0.998	0.002
K76.6 Portal hypertension	0.000	0.998	0.002
N80.1 Endometriosis of ovary	0.002	0.998	0.000
E10.6 With other specified complications	0.000	0.998	0.002
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
J92 Pleural plaque	0.000	0.998	0.002
H05.0 Acute inflammation of orbit	0.000	0.998	0.002
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
I86.8 Varicose veins of other specified sites	0.000	0.998	0.002
N85.1 Endometrial adenomatous hyperplasia	0.000	0.998	0.002
T39.0 Salicylates	0.002	0.998	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.998	0.002
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.998	0.002
H61 Other disorders of external ear	0.002	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.998	0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
J30-J39 Other diseases of upper respiratory tract	0.000	0.998	0.002
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
H81.1 Benign paroxysmal vertigo	0.002	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.002	0.998	0.000
E10.5 With peripheral circulatory complications	0.000	0.998	0.002
N80.3 Endometriosis of pelvic peritoneum	0.002	0.998	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.998	0.002
Y45.0 Opioids and related analgesics	0.000	0.998	0.002
D21.0 Connective and other soft tissue of head, face and neck	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
C25.3 Pancreatic duct	0.002	0.998	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.002
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
N80 Endometriosis	0.002	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
T48.4 Expectorants	0.002	0.998	0.000
T48.3 Antitussives	0.002	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
T48.0 Oxytocic drugs	0.002	0.998	0.000
T42.1 Iminostilbenes	0.002	0.998	0.000
J37 Chronic laryngitis and laryngotracheitis	0.000	0.998	0.002
J36 Peritonsillar abscess	0.000	0.998	0.002
J92.0 Pleural plaque with presence of asbestos	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations