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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17461766
log Bayes Factor = 19.7173
Chromosome 20   position 54,975,770  (GRCh37) Explore rs17461766 on Ensembl!
Variant rs17461766 is part of Cluster X0155

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
Chapter II Neoplasms
0.996 0.004 0.000
E86 Volume depletion
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.996 0.004 0.000
I25.2 Old myocardial infarction
0.988 0.012 0.000
M20-M25 Other joint disorders
0.987 0.013 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.987 0.013 0.000
I60-I69 Cerebrovascular diseases
0.984 0.016 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.983 0.017 0.000
M70-M79 Other soft tissue disorders
0.981 0.019 0.000
Chapter XI Diseases of the digestive system
0.981 0.019 0.000
I50 Heart failure
0.979 0.021 0.000
I20 Angina pectoris
0.977 0.023 0.000
K90-K93 Other diseases of the digestive system
0.974 0.026 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.971 0.029 0.000
M25 Other joint disorders, not elsewhere classified
0.961 0.039 0.000
Chapter VI Diseases of the nervous system
0.961 0.039 0.000
M50-M54 Other dorsopathies
0.956 0.044 0.000
I26 Pulmonary embolism
0.954 0.046 0.000
K92 Other diseases of digestive system
0.954 0.046 0.000
I20.0 Unstable angina
0.953 0.047 0.000
I35 Nonrheumatic aortic valve disorders
0.949 0.051 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.945 0.055 0.000
R05 Cough
0.944 0.056 0.000
I50.0 Congestive heart failure
0.942 0.058 0.000
R00 Abnormalities of heart beat
0.940 0.060 0.000
K92.0 Haematemesis
0.937 0.063 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.933 0.067 0.000
M75 Shoulder lesions
0.932 0.068 0.000
I71 Aortic aneurysm and dissection
0.931 0.069 0.000
I51 Complications and ill-defined descriptions of heart disease
0.925 0.075 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.925 0.075 0.000
E83 Disorders of mineral metabolism
0.922 0.078 0.000
I34 Nonrheumatic mitral valve disorders
0.921 0.079 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.921 0.079 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.921 0.079 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.917 0.083 0.000
C15-C26 Malignant neoplasms of digestive organs
0.916 0.084 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.915 0.085 0.000
I45 Other conduction disorders
0.914 0.086 0.000
M05-M14 Inflammatory polyarthropathies
0.914 0.086 0.000
M25.5 Pain in joint
0.913 0.087 0.000
Chapter XXI Factors influencing health status and contact with health services
0.911 0.089 0.000
M75.1 Rotator cuff syndrome
0.907 0.093 0.000
K70-K77 Diseases of liver
0.905 0.095 0.000
I05-I09 Chronic rheumatic heart diseases
0.901 0.099 0.000
K65-K67 Diseases of peritoneum
0.900 0.100 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.894 0.106 0.000
C18 Malignant neoplasm of colon
0.892 0.108 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.892 0.108 0.000
M51 Other intervertebral disk disorders
0.890 0.110 0.000
M50 Cervical disk disorders
0.881 0.119 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.880 0.120 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.879 0.121 0.000
C60-C63 Malignant neoplasms of male genital organs
0.877 0.123 0.000
I34.0 Mitral (valve) insufficiency
0.877 0.123 0.000
K91.4 Colostomy and enterostomy malfunction
0.877 0.123 0.000
G90-G99 Other disorders of the nervous system
0.872 0.128 0.000
I50.1 Left ventricular failure
0.870 0.130 0.000
I27 Other pulmonary heart diseases
0.870 0.130 0.000
I67 Other cerebrovascular diseases
0.869 0.131 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.869 0.131 0.000
I35.1 Aortic (valve) insufficiency
0.867 0.133 0.000
E83.5 Disorders of calcium metabolism
0.867 0.133 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.865 0.135 0.000
C64-C68 Malignant neoplasms of urinary tract
0.865 0.135 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.864 0.136 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.863 0.137 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.859 0.141 0.000
Z86 Personal history of certain other diseases
0.858 0.142 0.000
D00-D09 In situ neoplasms
0.857 0.143 0.000
Z86.7 Personal history of diseases of the circulatory system
0.855 0.145 0.000
M24 Other specific joint derangements
0.849 0.151 0.000
I47 Paroxysmal tachycardia
0.849 0.151 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.848 0.152 0.000
M51.2 Other specified intervertebral disk displacement
0.848 0.152 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.845 0.155 0.000
I49 Other cardiac arrhythmias
0.843 0.157 0.000
I51.9 Heart disease, unspecified
0.842 0.158 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.841 0.159 0.000
C50-C50 Malignant neoplasm of breast
0.841 0.159 0.000
Chapter X Diseases of the respiratory system
0.840 0.160 0.000
R00.1 Bradycardia, unspecified
0.840 0.160 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.838 0.162 0.000
I45.1 Other and unspecified right bundle-branch block
0.836 0.164 0.000
E78.5 Hyperlipidaemia, unspecified
0.835 0.165 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.832 0.168 0.000
K75 Other inflammatory liver diseases
0.831 0.169 0.000
I63 Cerebral infarction
0.830 0.170 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.829 0.171 0.000
M10 Gout
0.827 0.173 0.000
M25.56 Pain in joint (Lower leg)
0.827 0.173 0.000
I20.9 Angina pectoris, unspecified
0.825 0.175 0.000
I35.0 Aortic (valve) stenosis
0.824 0.176 0.000
I69 Sequelae of cerebrovascular disease
0.823 0.177 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.819 0.181 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.818 0.182 0.000
Z95.1 Presence of aortocoronary bypass graft
0.814 0.186 0.000
C18.9 Colon, unspecified
0.813 0.187 0.000
I73 Other peripheral vascular diseases
0.813 0.187 0.000
Chapter V Mental and behavioural disorders
0.812 0.188 0.000
E20-E35 Disorders of other endocrine glands
0.811 0.189 0.000
Z92 Personal history of medical treatment
0.811 0.189 0.000
I08 Multiple valve diseases
0.811 0.189 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.809 0.190 0.000
I42 Cardiomyopathy
0.808 0.192 0.000
I21 Acute myocardial infarction
0.803 0.197 0.000
M31 Other necrotising vasculopathies
0.803 0.197 0.000
Chapter XXII Codes for special purposes
0.802 0.198 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.802 0.198 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.798 0.202 0.000
D37.5 Rectum
0.798 0.202 0.000
R00.2 Palpitations
0.797 0.203 0.000
K66 Other disorders of peritoneum
0.796 0.204 0.000
I27.2 Other secondary pulmonary hypertension
0.796 0.204 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.795 0.205 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.793 0.207 0.000
C61 Malignant neoplasm of prostate
0.792 0.208 0.000
I74 Arterial embolism and thrombosis
0.789 0.211 0.000
C18.0 Caecum
0.786 0.214 0.000
Chapter VIII Diseases of the ear and mastoid process
0.786 0.214 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.785 0.215 0.000
M25.7 Osteophyte
0.784 0.216 0.000
M07 Psoriatic and enteropathic arthropathies
0.783 0.217 0.000
G81 Hemiplegia
0.783 0.217 0.000
I36 Nonrheumatic tricuspid valve disorders
0.780 0.220 0.000
I61 Intracerebral haemorrhage
0.779 0.221 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.778 0.222 0.000
R00.0 Tachycardia, unspecified
0.778 0.222 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.778 0.222 0.000
M65-M68 Disorders of synovium and tendon
0.774 0.225 0.000
Z80 Family history of malignant neoplasm
0.774 0.226 0.000
R01 Cardiac murmurs and other cardiac sounds
0.774 0.226 0.000
M50.0 Cervical disk disorder with myelopathy
0.773 0.227 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.771 0.229 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.771 0.229 0.000
R40 Somnolence, stupor and coma
0.766 0.234 0.000
M25.51 Pain in joint (Shoulder region)
0.765 0.234 0.000
M10.9 Gout, unspecified
0.765 0.235 0.000
E00-E07 Disorders of thyroid gland
0.764 0.236 0.000
R73 Elevated blood glucose level
0.762 0.238 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.762 0.238 0.000
E88 Other metabolic disorders
0.761 0.239 0.000
J09-J18 Influenza and pneumonia
0.761 0.239 0.000
K65 Peritonitis
0.759 0.241 0.000
I33 Acute and subacute endocarditis
0.758 0.241 0.000
I38 Endocarditis, valve unspecified
0.757 0.243 0.000
Z86.0 Personal history of other neoplasms
0.757 0.243 0.000
J30-J39 Other diseases of upper respiratory tract
0.756 0.244 0.000
R21 Rash and other nonspecific skin eruption
0.756 0.244 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.756 0.244 0.000
R71 Abnormality of red blood cells
0.756 0.244 0.000
E78.0 Pure hypercholesterolaemia
0.755 0.245 0.000
M25.9 Joint disorder, unspecified
0.755 0.245 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.753 0.246 0.000
K92.1 Melaena
0.753 0.247 0.000
M75.0 Adhesive capsulitis of shoulder
0.753 0.247 0.000
M25.4 Effusion of joint
0.752 0.248 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.752 0.248 0.000
M91-M94 Chondropathies
0.751 0.248 0.000
M25.54 Pain in joint (Hand)
0.751 0.249 0.000
M86-M90 Other osteopathies
0.750 0.250 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.750 0.250 0.000
M50.2 Other cervical disk displacement
0.749 0.251 0.000
I51.7 Cardiomegaly
0.749 0.251 0.000
I22 Subsequent myocardial infarction
0.746 0.254 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.742 0.258 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.740 0.259 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.740 0.260 0.000
M77 Other enthesopathies
0.740 0.260 0.000
K75.4 Autoimmune hepatitis
0.738 0.262 0.000
Z89 Acquired absence of limb
0.734 0.266 0.000
I60 Subarachnoid haemorrhage
0.734 0.266 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.733 0.267 0.000
M79.6 Pain in limb
0.733 0.267 0.000
I49.9 Cardiac arrhythmia, unspecified
0.732 0.267 0.000
I47.2 Ventricular tachycardia
0.731 0.269 0.000
M20 Acquired deformities of fingers and toes
0.731 0.269 0.000
C34 Malignant neoplasm of bronchus and lung
0.730 0.270 0.000
M22 Disorders of patella
0.729 0.271 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.729 0.271 0.000
C50 Malignant neoplasm of breast
0.729 0.271 0.000
I73.9 Peripheral vascular disease, unspecified
0.728 0.272 0.000
C51-C58 Malignant neoplasms of female genital organs
0.728 0.272 0.000
K74 Fibrosis and cirrhosis of liver
0.727 0.273 0.000
M25.53 Pain in joint (Forearm)
0.726 0.274 0.000
G81.9 Hemiplegia, unspecified
0.725 0.275 0.000
I80 Phlebitis and thrombophlebitis
0.724 0.276 0.000
K66.0 Peritoneal adhesions
0.722 0.278 0.000
C18.5 Splenic flexure
0.721 0.279 0.000
I63.9 Cerebral infarction, unspecified
0.721 0.279 0.000
E83.1 Disorders of iron metabolism
0.721 0.279 0.000
D37.4 Colon
0.719 0.281 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.719 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
E85 Amyloidosis
0.716 0.283 0.000
E84 Cystic fibrosis
0.716 0.283 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.716 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.283 0.000
E73 Lactose intolerance
0.716 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.285 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.714 0.285 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.714 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.285 0.000
I25.5 Ischaemic cardiomyopathy
0.714 0.286 0.000
G30-G32 Other degenerative diseases of the nervous system
0.714 0.286 0.000
R07 Pain in throat and chest
0.714 0.286 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.286 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.710 0.290 0.000
I45.5 Other specified heart block
0.710 0.290 0.000
M10.99 Gout, unspecified (Site unspecified)
0.709 0.291 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.708 0.292 0.000
M34 Systemic sclerosis
0.708 0.292 0.000
M33 Dermatopolymyositis
0.708 0.292 0.000
M32 Systemic lupus erythematosus
0.708 0.292 0.000
M30 Polyarteritis nodosa and related conditions
0.708 0.292 0.000
M21 Other acquired deformities of limbs
0.708 0.292 0.000
M24.1 Other articular cartilage disorders
0.707 0.292 0.000
Z95.3 Presence of xenogenic heart valve
0.707 0.293 0.000
D06 Carcinoma in situ of cervix uteri
0.706 0.294 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.705 0.294 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.705 0.294 0.000
I62 Other nontraumatic intracranial haemorrhage
0.705 0.294 0.000
C79 Secondary malignant neoplasm of other sites
0.705 0.295 0.000
I28 Other diseases of pulmonary vessels
0.705 0.295 0.000
R42 Dizziness and giddiness
0.705 0.295 0.000
M75.3 Calcific tendinitis of shoulder
0.704 0.296 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.704 0.296 0.000
I67.2 Cerebral atherosclerosis
0.703 0.297 0.000
M45-M49 Spondylopathies
0.703 0.297 0.000
M76 Enthesopathies of lower limb, excluding foot
0.703 0.297 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.703 0.297 0.000
M71 Other bursopathies
0.703 0.297 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.703 0.297 0.000
M79.8 Other specified soft tissue disorders
0.702 0.298 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.701 0.299 0.000
M25.50 Pain in joint (Multiple sites)
0.701 0.299 0.000
I07 Rheumatic tricuspid valve diseases
0.701 0.299 0.000
I20.1 Angina pectoris with documented spasm
0.700 0.300 0.000
I77 Other disorders of arteries and arterioles
0.700 0.300 0.000
G40-G47 Episodic and paroxysmal disorders
0.700 0.300 0.000
G20-G26 Extrapyramidal and movement disorders
0.699 0.301 0.000
M40-M43 Deforming dorsopathies
0.699 0.301 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.698 0.301 0.000
K75.8 Other specified inflammatory liver diseases
0.698 0.302 0.000
I42.0 Dilated cardiomyopathy
0.696 0.303 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.696 0.304 0.000
I72 Other aneurysm
0.696 0.304 0.000
I70 Atherosclerosis
0.696 0.304 0.000
I67.8 Other specified cerebrovascular diseases
0.696 0.304 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.695 0.304 0.000
Z95.4 Presence of other heart-valve replacement
0.695 0.305 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.693 0.307 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.691 0.308 0.000
G90 Disorders of autonomic nervous system
0.691 0.309 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.691 0.309 0.000
K70 Alcoholic liver disease
0.691 0.309 0.000
C18.2 Ascending colon
0.690 0.310 0.000
M07.3 Other psoriatic arthropathies
0.690 0.310 0.000
M25.8 Other specified joint disorders
0.689 0.311 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.689 0.311 0.000
M25.3 Other instability of joint
0.689 0.311 0.000
M25.2 Flail joint
0.689 0.311 0.000
M25.1 Fistula of joint
0.689 0.311 0.000
M25.0 Haemarthrosis
0.689 0.311 0.000
G70-G73 Diseases of myoneural junction and muscle
0.689 0.311 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.689 0.311 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.689 0.311 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.689 0.311 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.687 0.312 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.687 0.313 0.000
Chapter XX External causes of morbidity and mortality
0.687 0.313 0.000
M70.6 Trochanteric bursitis
0.687 0.313 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.686 0.314 0.000
M11 Other crystal arthropathies
0.686 0.314 0.000
C80 Malignant neoplasm without specification of site
0.686 0.314 0.000
M53 Other dorsopathies, not elsewhere classified
0.685 0.315 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.684 0.316 0.000
K92.8 Other specified diseases of digestive system
0.684 0.316 0.000
G62 Other polyneuropathies
0.684 0.316 0.000
Z98 Other postsurgical states
0.683 0.317 0.000
I50.9 Heart failure, unspecified
0.682 0.317 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.682 0.318 0.000
C18.3 Hepatic flexure
0.681 0.319 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.681 0.319 0.000
I35.9 Aortic valve disorder, unspecified
0.681 0.319 0.000
I35.8 Other aortic valve disorders
0.681 0.319 0.000
R45 Symptoms and signs involving emotional state
0.680 0.320 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.680 0.320 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.679 0.321 0.000
K55-K64 Other diseases of intestines
0.677 0.323 0.000
D04 Carcinoma in situ of skin
0.677 0.323 0.000
J18 Pneumonia, organism unspecified
0.676 0.324 0.000
I51.8 Other ill-defined heart diseases
0.676 0.324 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.674 0.326 0.000
I67.9 Cerebrovascular disease, unspecified
0.674 0.326 0.000
M35 Other systemic involvement of connective tissue
0.673 0.327 0.000
M50.1 Cervical disk disorder with radiculopathy
0.673 0.327 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.673 0.327 0.000
I49.8 Other specified cardiac arrhythmias
0.672 0.328 0.000
R81 Glycosuria
0.671 0.329 0.000
M31.6 Other giant cell arteritis
0.671 0.329 0.000
I87 Other disorders of veins
0.670 0.330 0.000
M75.8 Other shoulder lesions
0.669 0.331 0.000
M75.9 Shoulder lesion, unspecified
0.669 0.331 0.000
M75.2 Bicipital tendinitis
0.669 0.331 0.000
M23 Internal derangement of knee
0.668 0.331 0.000
Z93 Artificial opening status
0.668 0.332 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.667 0.333 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.667 0.333 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.667 0.333 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.667 0.333 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.667 0.333 0.000
I71.0 Dissection of aorta [any part]
0.667 0.333 0.000
K92.9 Disease of digestive system, unspecified
0.665 0.335 0.000
Z95.2 Presence of prosthetic heart valve
0.665 0.335 0.000
I86 Varicose veins of other sites
0.665 0.335 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.664 0.335 0.000
I95 Hypotension
0.664 0.336 0.000
I51.6 Cardiovascular disease, unspecified
0.663 0.336 0.000
I51.5 Myocardial degeneration
0.663 0.336 0.000
I51.4 Myocarditis, unspecified
0.663 0.336 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.663 0.336 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.663 0.336 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.663 0.336 0.000
I51.0 Cardiac septal defect, acquired
0.663 0.336 0.000
E78.8 Other disorders of lipoprotein metabolism
0.663 0.337 0.000
E78.6 Lipoprotein deficiency
0.663 0.337 0.000
E78.4 Other hyperlipidaemia
0.663 0.337 0.000
E78.3 Hyperchylomicronaemia
0.663 0.337 0.000
E78.2 Mixed hyperlipidaemia
0.663 0.337 0.000
E78.1 Pure hyperglyceridaemia
0.663 0.337 0.000
R41.0 Disorientation, unspecified
0.663 0.337 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.663 0.337 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.662 0.337 0.000
E50-E64 Other nutritional deficiencies
0.662 0.338 0.000
O80-O84 Delivery
0.662 0.338 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.662 0.338 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.661 0.339 0.000
E83.8 Other disorders of mineral metabolism
0.661 0.339 0.000
E83.3 Disorders of phosphorus metabolism
0.661 0.339 0.000
E83.2 Disorders of zinc metabolism
0.661 0.339 0.000
E83.0 Disorders of copper metabolism
0.661 0.339 0.000
E27 Other disorders of adrenal gland
0.661 0.339 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.661 0.339 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.661 0.339 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.661 0.339 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.661 0.339 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.660 0.339 0.000
K91.5 Postcholecystectomy syndrome
0.660 0.339 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.660 0.339 0.000
K91.1 Postgastric surgery syndromes
0.660 0.339 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.660 0.339 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.660 0.340 0.000
D46 Myelodysplastic syndromes
0.660 0.340 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.660 0.340 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.660 0.340 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.660 0.340 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.660 0.340 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.660 0.340 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.660 0.340 0.000
R40.2 Coma, unspecified
0.658 0.342 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.658 0.342 0.000
D03 Melanoma in situ
0.658 0.342 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.657 0.343 0.000
R77 Other abnormalities of plasma proteins
0.657 0.343 0.000
R76 Other abnormal immunological findings in serum
0.657 0.343 0.000
R74 Abnormal serum enzyme levels
0.657 0.343 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.657 0.343 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.657 0.343 0.000
E89.2 Postprocedural hypoparathyroidism
0.657 0.343 0.000
Z92.0 Personal history of contraception
0.657 0.343 0.000
D45 Polycythaemia vera
0.657 0.343 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.657 0.343 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.657 0.343 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.657 0.343 0.000
C21 Malignant neoplasm of anus and anal canal
0.657 0.343 0.000
C17 Malignant neoplasm of small intestine
0.657 0.343 0.000
C16 Malignant neoplasm of stomach
0.657 0.343 0.000
C23 Malignant neoplasm of gallbladder
0.657 0.343 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.657 0.343 0.000
F80-F89 Disorders of psychological development
0.656 0.344 0.000
R46 Symptoms and signs involving appearance and behaviour
0.656 0.344 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.656 0.344 0.000
R43 Disturbances of smell and taste
0.656 0.344 0.000
I65.2 Occlusion and stenosis of carotid artery
0.656 0.344 0.000
I45.9 Conduction disorder, unspecified
0.655 0.344 0.000
I45.8 Other specified conduction disorders
0.655 0.344 0.000
I45.6 Preexcitation syndrome
0.655 0.344 0.000
I45.4 Nonspecific intraventricular block
0.655 0.344 0.000
I45.3 Trifascicular block
0.655 0.344 0.000
I45.2 Bifascicular block
0.655 0.344 0.000
I45.0 Right fascicular block
0.655 0.344 0.000
K72 Hepatic failure, not elsewhere classified
0.655 0.345 0.000
M14 Arthropathies in other diseases classified elsewhere
0.655 0.345 0.000
M12 Other specific arthropathies
0.655 0.345 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.655 0.345 0.000
M08 Juvenile arthritis
0.655 0.345 0.000
M05 Seropositive rheumatoid arthritis
0.655 0.345 0.000
M25.59 Pain in joint (Site unspecified)
0.655 0.345 0.000
M25.58 Pain in joint (Other)
0.655 0.345 0.000
M25.52 Pain in joint (Upper arm)
0.655 0.345 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.655 0.345 0.000
M80-M85 Disorders of bone density and structure
0.654 0.346 0.000
K65.0 Acute peritonitis
0.654 0.346 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.653 0.347 0.000
G83 Other paralytic syndromes
0.652 0.348 0.000
J39 Other diseases of upper respiratory tract
0.650 0.350 0.000
I67.1 Cerebral aneurysm, nonruptured
0.650 0.350 0.000
I46 Cardiac arrest
0.650 0.350 0.000
K77 Liver disorders in diseases classified elsewhere
0.649 0.351 0.000
K73 Chronic hepatitis, not elsewhere classified
0.649 0.351 0.000
K71 Toxic liver disease
0.649 0.351 0.000
R47-R49 Symptoms and signs involving speech and voice
0.649 0.351 0.000
G96 Other disorders of central nervous system
0.649 0.351 0.000
K57 Diverticular disease of intestine
0.647 0.353 0.000
C01 Malignant neoplasm of base of tongue
0.647 0.353 0.000
R73.9 Hyperglycaemia, unspecified
0.646 0.354 0.000
I09 Other rheumatic heart diseases
0.646 0.354 0.000
I06 Rheumatic aortic valve diseases
0.646 0.354 0.000
I05 Rheumatic mitral valve diseases
0.646 0.354 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.646 0.354 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.645 0.354 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.643 0.357 0.000
I49.4 Other and unspecified premature depolarisation
0.643 0.357 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.642 0.358 0.000
Z84 Family history of other conditions
0.641 0.359 0.000
Z81 Family history of mental and behavioural disorders
0.641 0.359 0.000
C18.8 Overlapping lesion of colon
0.640 0.360 0.000
C18.6 Descending colon
0.640 0.360 0.000
C18.4 Transverse colon
0.640 0.360 0.000
C18.1 Appendix
0.640 0.360 0.000
K90 Intestinal malabsorption
0.640 0.360 0.000
Z97 Presence of other devices
0.640 0.360 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.639 0.361 0.000
Z94 Transplanted organ and tissue status
0.639 0.361 0.000
M51.3 Other specified intervertebral disk degeneration
0.638 0.362 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.638 0.362 0.000
M51.9 Intervertebral disk disorder, unspecified
0.638 0.362 0.000
M51.8 Other specified intervertebral disk disorders
0.638 0.362 0.000
M51.4 Schmorl's nodes
0.638 0.362 0.000
I08.0 Disorders of both mitral and aortic valves
0.637 0.363 0.000
G95 Other diseases of spinal cord
0.637 0.363 0.000
M06 Other rheumatoid arthritis
0.636 0.364 0.000
I85 Oesophageal varices
0.636 0.364 0.000
D09 Carcinoma in situ of other and unspecified sites
0.636 0.364 0.000
G93 Other disorders of brain
0.636 0.364 0.000
I69.3 Sequelae of cerebral infarction
0.635 0.365 0.000
M72 Fibroblastic disorders
0.634 0.365 0.000
K91.3 Postoperative intestinal obstruction
0.633 0.367 0.000
R79 Other abnormal findings of blood chemistry
0.633 0.367 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.633 0.367 0.000
M50.9 Cervical disk disorder, unspecified
0.632 0.368 0.000
M50.8 Other cervical disk disorders
0.632 0.368 0.000
J35 Chronic diseases of tonsils and adenoids
0.632 0.368 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.631 0.369 0.000
C15 Malignant neoplasm of oesophagus
0.631 0.369 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.631 0.369 0.000
C77.1 Intrathoracic lymph nodes
0.630 0.370 0.000
M79.0 Rheumatism, unspecified
0.630 0.370 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.629 0.371 0.000
C62 Malignant neoplasm of testis
0.629 0.371 0.000
C60 Malignant neoplasm of penis
0.629 0.371 0.000
I47.1 Supraventricular tachycardia
0.628 0.372 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.628 0.372 0.000
I81 Portal vein thrombosis
0.628 0.372 0.000
I74.5 Embolism and thrombosis of iliac artery
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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