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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17496549
log Bayes Factor = 86.6383
Chromosome 6   position 32,409,708  (GRCh37) Explore rs17496549 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
1.000 0.000 0.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.999 0.000 0.001
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
K50-K52 Noninfective enteritis and colitis
0.999 0.001 0.000
K50.1 Crohn's disease of large intestine
0.999 0.001 0.000
K50 Crohn's disease [regional enteritis]
0.999 0.001 0.000
C44.7 Skin of lower limb, including hip
0.998 0.002 0.000
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
M06.0 Seronegative rheumatoid arthritis
0.998 0.002 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.997 0.003 0.000
E03 Other hypothyroidism
0.000 0.004 0.996
C44.2 Skin of ear and external auricular canal
0.996 0.004 0.000
M05-M14 Inflammatory polyarthropathies
0.995 0.005 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.995 0.005 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.005 0.995
K51.4 Pseudopolyposis of colon
0.994 0.006 0.000
C44.5 Skin of trunk
0.994 0.006 0.000
Z93.2 Ileostomy status
0.994 0.006 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.993 0.007 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.991 0.009 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.991 0.009 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.010 0.990
M05 Seropositive rheumatoid arthritis
0.987 0.013 0.000
C83.3 Large cell (diffuse)
0.987 0.013 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.981 0.019 0.000
C44.4 Skin of scalp and neck
0.981 0.019 0.000
Chapter II Neoplasms
0.581 0.027 0.391
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.029 0.971
E10.3 With ophthalmic complications
0.000 0.030 0.970
E27 Other disorders of adrenal gland
0.000 0.032 0.968
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.039 0.961
D50-D53 Nutritional anaemias
0.000 0.039 0.961
D86 Sarcoidosis
0.000 0.040 0.960
D86.9 Sarcoidosis, unspecified
0.000 0.041 0.959
M07 Psoriatic and enteropathic arthropathies
0.958 0.042 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.042 0.958
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.046 0.954
D50 Iron deficiency anaemia
0.000 0.048 0.952
D50.9 Iron deficiency anaemia, unspecified
0.000 0.048 0.952
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.050 0.950
E27.1 Primary adrenocortical insufficiency
0.000 0.051 0.949
D80-D89 Certain disorders involving the immune mechanism
0.002 0.054 0.944
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.003 0.055 0.942
K50.9 Crohn's disease, unspecified
0.943 0.057 0.000
D86.0 Sarcoidosis of lung
0.000 0.060 0.940
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.062 0.938
E21.0 Primary hyperparathyroidism
0.000 0.065 0.935
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.934 0.066 0.000
M07.3 Other psoriatic arthropathies
0.932 0.068 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.880 0.072 0.048
E10.1 With ketoacidosis
0.000 0.074 0.926
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.921 0.079 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.919 0.081 0.000
K51.8 Other ulcerative colitis
0.918 0.082 0.000
C44.0 Skin of lip
0.915 0.085 0.000
C82.0 Small cleaved cell, follicular
0.908 0.092 0.000
K51.2 Ulcerative (chronic) proctitis
0.899 0.101 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.899 0.101 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.895 0.105 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.107 0.893
K90 Intestinal malabsorption
0.005 0.109 0.886
C44.6 Skin of upper limb, including shoulder
0.879 0.121 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.128 0.872
C44.1 Skin of eyelid, including canthus
0.861 0.139 0.000
M06.3 Rheumatoid nodule
0.855 0.145 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.855 0.145 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.853 0.147 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.151 0.849
E14 Unspecified diabetes mellitus
0.000 0.160 0.840
E22 Hyperfunction of pituitary gland
0.000 0.162 0.838
C82.3 Follicular lymphoma grade IIIa
0.836 0.164 0.000
K51.5 Mucosal proctocolitis
0.825 0.175 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.185 0.815
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.002 0.188 0.810
M07.30 Other psoriatic arthropathies (Multiple sites)
0.812 0.188 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.808 0.192 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.807 0.193 0.000
D52 Folate deficiency anaemia
0.000 0.195 0.804
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.803 0.197 0.000
E20 Hypoparathyroidism
0.000 0.199 0.801
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.800 0.200 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.799 0.201 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.793 0.207 0.000
E10.8 With unspecified complications
0.000 0.209 0.790
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.787 0.212 0.000
C85.1 B-cell lymphoma, unspecified
0.787 0.213 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.781 0.219 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.779 0.221 0.000
E27.2 Addisonian crisis
0.000 0.227 0.773
C82.2 Large cell, follicular
0.770 0.230 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.231 0.769
E21.3 Hyperparathyroidism, unspecified
0.000 0.232 0.768
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.764 0.236 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.760 0.240 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.247 0.753
C43 Malignant melanoma of skin
0.746 0.249 0.004
K90.9 Intestinal malabsorption, unspecified
0.002 0.250 0.748
E10.0 With coma
0.000 0.254 0.745
E24 Cushing's syndrome
0.000 0.255 0.745
K51.3 Ulcerative (chronic) rectosigmoiditis
0.745 0.255 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.745 0.255 0.000
E10.5 With peripheral circulatory complications
0.000 0.259 0.741
E14.9 Without complications
0.000 0.266 0.734
C83.1 Small cleaved cell (diffuse)
0.734 0.266 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.734 0.266 0.000
M45 Ankylosing spondylitis
0.732 0.268 0.000
E10.6 With other specified complications
0.000 0.271 0.729
E65-E68 Obesity and other hyperalimentation
0.000 0.273 0.727
C84 Peripheral and cutaneous T-cell lymphomas
0.725 0.274 0.001
C82.1 Mixed small cleaved and large cell, follicular
0.724 0.276 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.722 0.277 0.000
E03.8 Other specified hypothyroidism
0.000 0.278 0.722
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
C82.6 Cutaneous follicle centre lymphoma
0.717 0.283 0.000
C82.5 Diffuse follicle centre lymphoma
0.717 0.283 0.000
C82.4 Follicular lymphoma grade IIIb
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.716 0.283 0.001
C95 Leukaemia of unspecified cell type
0.716 0.283 0.001
C94 Other leukaemias of specified cell type
0.716 0.283 0.001
C93 Monocytic leukaemia
0.716 0.283 0.001
C86 Other specified types of T/NK-cell lymphoma
0.716 0.283 0.001
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.715
M06.08 Seronegative rheumatoid arthritis (Other)
0.715 0.285 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.715 0.285 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.715 0.285 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.715 0.285 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.715 0.285 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.715 0.285 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.715 0.285 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.715 0.285 0.000
C85.0 Lymphosarcoma
0.715 0.285 0.000
M06.34 Rheumatoid nodule (Hand)
0.715 0.285 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.575 0.285 0.139
E03.5 Myxoedema coma
0.000 0.286 0.714
E03.4 Atrophy of thyroid (acquired)
0.000 0.286 0.714
E03.3 Postinfectious hypothyroidism
0.000 0.286 0.714
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.286 0.714
E03.1 Congenital hypothyroidism without goitre
0.000 0.286 0.714
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.286 0.714
M12 Other specific arthropathies
0.713 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.713 0.286 0.000
M08 Juvenile arthritis
0.713 0.286 0.000
E40-E46 Malnutrition
0.000 0.287 0.713
C83.7 Burkitt's tumour
0.712 0.288 0.000
C83.6 Undifferentiated (diffuse)
0.712 0.288 0.000
C83.5 Lymphoblastic (diffuse)
0.712 0.288 0.000
C83.4 Immunoblastic (diffuse)
0.712 0.288 0.000
C83.2 Mixed small and large cell (diffuse)
0.712 0.288 0.000
M06.4 Inflammatory polyarthropathy
0.711 0.289 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.290 0.710
E32 Diseases of thymus
0.000 0.290 0.710
E31 Polyglandular dysfunction
0.000 0.290 0.710
E30 Disorders of puberty, not elsewhere classified
0.000 0.290 0.710
E25 Adrenogenital disorders
0.000 0.290 0.710
M14 Arthropathies in other diseases classified elsewhere
0.709 0.291 0.000
M05.8 Other seropositive rheumatoid arthritis
0.707 0.292 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.707 0.292 0.000
M05.2 Rheumatoid vasculitis
0.707 0.292 0.000
M05.1 Rheumatoid lung disease
0.707 0.292 0.000
M05.0 Felty's syndrome
0.707 0.292 0.000
C88 Malignant immunoproliferative diseases
0.706 0.293 0.001
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.703 0.297 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.703 0.297 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.703 0.297 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.703 0.297 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.703 0.297 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.703 0.297 0.000
M45-M49 Spondylopathies
0.703 0.297 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.702 0.297 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.438 0.298 0.263
M11 Other crystal arthropathies
0.700 0.300 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.699 0.301 0.000
E10.4 With neurological complications
0.000 0.303 0.697
E29 Testicular dysfunction
0.000 0.304 0.696
E05.5 Thyroid crisis or storm
0.000 0.304 0.696
E05.4 Thyrotoxicosis factitia
0.000 0.304 0.696
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.304 0.696
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.304 0.696
E13 Other specified diabetes mellitus
0.000 0.305 0.695
K52 Other non-infective gastro-enteritis and colitis
0.695 0.305 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.306 0.694
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.306 0.694
E27.0 Other adrenocortical overactivity
0.000 0.306 0.694
D52.9 Folate deficiency anaemia, unspecified
0.000 0.308 0.692
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.213 0.308 0.479
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.311 0.689
E21.4 Other specified disorders of parathyroid gland
0.000 0.311 0.689
E21.2 Other hyperparathyroidism
0.000 0.311 0.689
E27.8 Other specified disorders of adrenal gland
0.000 0.311 0.689
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.311 0.689
D86.3 Sarcoidosis of skin
0.000 0.311 0.688
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.311 0.688
D86.1 Sarcoidosis of lymph nodes
0.000 0.311 0.688
M07.6 Other enteropathic arthropathies
0.687 0.313 0.000
M07.5 Arthropathy in ulcerative colitis
0.687 0.313 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.687 0.313 0.000
M07.2 Psoriatic spondylitis
0.687 0.313 0.000
M07.1 Arthritis mutilans
0.687 0.313 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.687 0.313 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.448 0.313 0.239
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.313 0.687
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.313 0.687
D51.2 Transcobalamin II deficiency
0.000 0.313 0.687
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.313 0.687
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.316 0.684
D50.1 Sideropenic dysphagia
0.000 0.317 0.683
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.683 0.317 0.000
E05.8 Other thyrotoxicosis
0.000 0.321 0.679
D83 Common variable immunodeficiency
0.002 0.321 0.677
D82 Immunodeficiency associated with other major defects
0.002 0.321 0.677
D81 Combined immunodeficiencies
0.002 0.321 0.677
E16.1 Other hypoglycaemia
0.000 0.323 0.677
K50.8 Other Crohn's disease
0.677 0.323 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.676 0.324 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.675 0.325 0.000
D55-D59 Haemolytic anaemias
0.002 0.327 0.671
E15 Nondiabetic hypoglycaemic coma
0.000 0.328 0.672
E05.9 Thyrotoxicosis, unspecified
0.000 0.331 0.669
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.331 0.669
M07.38 Other psoriatic arthropathies (Other)
0.668 0.332 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.668 0.332 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.668 0.332 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.668 0.332 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.668 0.332 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.668 0.332 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.334 0.666
D53 Other nutritional anaemias
0.000 0.342 0.658
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.568 0.343 0.088
E10.2 With renal complications
0.000 0.353 0.647
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.355 0.644
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.359 0.641
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.359 0.641
E16.4 Abnormal secretion of gastrin
0.000 0.359 0.641
E16.3 Increased secretion of glucagon
0.000 0.359 0.641
K90.3 Pancreatic steatorrhoea
0.004 0.361 0.635
K90.2 Blind loop syndrome, not elsewhere classified
0.004 0.361 0.635
K90.1 Tropical sprue
0.004 0.361 0.635
C83.0 Small cell (diffuse)
0.636 0.363 0.000
K90.8 Other intestinal malabsorption
0.004 0.363 0.633
E07 Other disorders of thyroid
0.000 0.364 0.636
E14.3 With ophthalmic complications
0.000 0.371 0.629
C34 Malignant neoplasm of bronchus and lung
0.004 0.377 0.619
# Top node
0.251 0.377 0.372
J45 Asthma
0.027 0.379 0.595
C34.9 Bronchus or lung, unspecified
0.000 0.382 0.618
M06.32 Rheumatoid nodule (Upper arm)
0.617 0.383 0.000
M46 Other inflammatory spondylopathies
0.614 0.386 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.613 0.387 0.000
M06.38 Rheumatoid nodule (Other)
0.613 0.387 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.613 0.387 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.613 0.387 0.000
M06.33 Rheumatoid nodule (Forearm)
0.613 0.387 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.613 0.387 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.613 0.387 0.000
E50-E64 Other nutritional deficiencies
0.000 0.387 0.613
M65-M68 Disorders of synovium and tendon
0.611 0.389 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.410 0.391 0.199
C43.4 Malignant melanoma of scalp and neck
0.606 0.392 0.002
C81 Hodgkin's disease
0.604 0.395 0.001
E14.8 With unspecified complications
0.000 0.398 0.602
E14.7 With multiple complications
0.000 0.398 0.602
E14.6 With other specified complications
0.000 0.398 0.602
E14.5 With peripheral circulatory complications
0.000 0.398 0.602
E14.2 Withrenal complications
0.000 0.398 0.602
E14.1 With ketoacidosis
0.000 0.398 0.602
E14.0 With coma
0.000 0.398 0.602
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.399 0.601
E22.8 Other hyperfunction of pituitary gland
0.000 0.399 0.601
Chapter XII Diseases of the skin and subcutaneous tissue
0.272 0.401 0.327
C34.3 Lower lobe, bronchus or lung
0.000 0.401 0.598
K52.1 Toxic gastro-enteritis and colitis
0.598 0.402 0.000
E66 Obesity
0.000 0.410 0.590
D80 Immunodeficiency with predominantly antibody defects
0.002 0.413 0.585
E24.9 Cushing's syndrome, unspecified
0.000 0.414 0.586
C73 Malignant neoplasm of thyroid gland
0.569 0.416 0.015
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.001 0.417 0.583
E34 Other endocrine disorders
0.000 0.417 0.583
E27.9 Disorder of adrenal gland, unspecified
0.000 0.417 0.582
D52.8 Other folate deficiency anaemias
0.000 0.423 0.577
D52.1 Drug-induced folate deficiency anaemia
0.000 0.423 0.577
D52.0 Dietary folate deficiency anaemia
0.000 0.423 0.577
D59 Acquired haemolytic anaemia
0.001 0.424 0.574
E20.8 Other hypoparathyroidism
0.000 0.425 0.574
E20.1 Pseudohypoparathyroidism
0.000 0.425 0.574
E20.0 Idiopathic hypoparathyroidism
0.000 0.425 0.574
C02 Malignant neoplasm of other and unspecified parts of tongue
0.549 0.426 0.025
E22.0 Acromegaly and pituitary gigantism
0.000 0.431 0.568
M45.X2 Ankylosing spondylitis (Cervical region)
0.566 0.433 0.000
M65 Synovitis and tenosynovitis
0.563 0.437 0.000
K52.3 Indeterminate colitis
0.560 0.440 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.557 0.443 0.000
E06 Thyroiditis
0.000 0.444 0.556
M00-M03 Infectious arthropathies
0.554 0.445 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.553 0.447 0.000
C34.0 Main bronchus
0.001 0.449 0.549
E14.4 With neurological complications
0.000 0.449 0.550
D84 Other immunodeficiencies
0.002 0.451 0.547
E66.9 Obesity, unspecified
0.000 0.451 0.549
C06 Malignant neoplasm of other and unspecified parts of mouth
0.500 0.454 0.046
M11.9 Crystal arthropathy, unspecified
0.545 0.454 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.314 0.456 0.230
C90 Multiple myeloma and malignant plasma cell neoplasms
0.542 0.457 0.001
M10 Gout
0.543 0.457 0.000
C43.8 Overlapping malignant melanoma of skin
0.535 0.462 0.003
C43.1 Malignant melanoma of eyelid, including canthus
0.535 0.462 0.003
C43.0 Malignant melanoma of lip
0.535 0.462 0.003
M65.9 Synovitis and tenosynovitis, unspecified
0.538 0.462 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.463 0.537
C64-C68 Malignant neoplasms of urinary tract
0.169 0.465 0.366
E24.8 Other Cushing's syndrome
0.000 0.465 0.534
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.465 0.534
E24.3 Ectopic ACTH syndrome
0.000 0.465 0.534
E24.1 Nelson's syndrome
0.000 0.465 0.534
E24.0 Pituitary-dependent Cushing's disease
0.000 0.465 0.534
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.534 0.466 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.441 0.468 0.092
C34.1 Upper lobe, bronchus or lung
0.000 0.470 0.529
C84.5 Other and unspecified T-cell lymphomas
0.526 0.473 0.001
C74 Malignant neoplasm of adrenal gland
0.435 0.473 0.092
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.525 0.475 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.525 0.475 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.525 0.475 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.525 0.475 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.525 0.475 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.525 0.475 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.525 0.475 0.000
C84.4 Peripheral T-cell lymphoma
0.522 0.477 0.001
E67 Other hyperalimentation
0.000 0.478 0.521
E68 Sequelae of hyperalimentation
0.000 0.478 0.521
C84.9 Mature T/NK-cell lymphoma, unspecified
0.520 0.480 0.001
C84.8 Cutaneous T-cell lymphoma, unspecified
0.520 0.480 0.001
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.520 0.480 0.001
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.520 0.480 0.001
C84.3 Lymphoepithelioid lymphoma
0.520 0.480 0.001
C84.2 T-zone lymphoma
0.520 0.480 0.001
C84.1 Sezary's diease
0.520 0.480 0.001
C84.0 Mycosis fungoides
0.520 0.480 0.001
M49 Spondylopathies in diseases classified elsewhere
0.519 0.481 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.002 0.484 0.514
M13 Other arthritis
0.515 0.485 0.000
C43.9 Malignant melanoma of skin, unspecified
0.512 0.485 0.003
E28 Ovarian dysfunction
0.000 0.485 0.514
E24.2 Drug-induced Cushing's syndrome
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.514 0.486 0.000
M06.18 Adult-onset Still's disease (Other)
0.514 0.486 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.514 0.486 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.514 0.486 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.514 0.486 0.000
M06.14 Adult-onset Still's disease (Hand)
0.514 0.486 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.514 0.486 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.514 0.486 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.514 0.486 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.514 0.486 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.514 0.486 0.000
M06.28 Rheumatoid bursitis (Other)
0.514 0.486 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.514 0.486 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.514 0.486 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.514 0.486 0.000
M06.24 Rheumatoid bursitis (Hand)
0.514 0.486 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.514 0.486 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.514 0.486 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.514 0.486 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.514 0.486 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.514 0.486 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.514 0.486 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.514 0.486 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.514 0.486 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.514 0.486 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.514 0.486 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.514 0.486 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.514 0.486 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.514 0.486 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.514 0.486 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.513 0.486 0.001
C86.5 Angioimmunoblastic T-cell lymphoma
0.513 0.486 0.001
C86.4 Blastic NK-cell lymphoma
0.513 0.486 0.001
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.513 0.486 0.001
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.513 0.486 0.001
C86.1 Hepatosplenic T-cell lymphoma
0.513 0.486 0.001
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.513 0.486 0.001
C93.9 Monocytic leukaemia, unspecified
0.513 0.486 0.001
C93.7 Other monocytic leukaemia
0.513 0.486 0.001
C93.3 Juvenile myelomonocytic leukaemia
0.513 0.486 0.001
C93.2 Subacute monocytic leukaemia
0.513 0.486 0.001
C93.1 Chronic monocytic leukaemia
0.513 0.486 0.001
C93.0 Acute monocytic leukaemia
0.513 0.486 0.001
C94.7 Other specified leukaemias
0.513 0.486 0.001
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.513 0.486 0.001
C94.5 Acute myelofibrosis
0.513 0.486 0.001
C94.4 Acute panmyelosis
0.513 0.486 0.001
C94.3 Mast cell leukaemia
0.513 0.486 0.001
C94.2 Acute megakaryoblastic leukaemia
0.513 0.486 0.001
C94.1 Chronic erythraemia
0.513 0.486 0.001
C94.0 Acute erythraemia and erythroleukaemia
0.513 0.486 0.001
C95.9 Leukaemia, unspecified
0.513 0.486 0.001
C95.7 Other leukaemia of unspecified cell type
0.513 0.486 0.001
C95.2 Subacute leukaemia of unspecified cell type
0.513 0.486 0.001
C95.1 Chronic leukaemia of unspecified cell type
0.513 0.486 0.001
C95.0 Acute leukaemia of unspecified cell type
0.513 0.486 0.001
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.513 0.486 0.001
C96.8 Histiocytic sarcoma
0.513 0.486 0.001
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.513 0.486 0.001
C96.6 Unifocal Langerhans-cell histiocytosis
0.513 0.486 0.001
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.513 0.486 0.001
C96.4 Sarcoma of dendritic cells (accessory cells)
0.513 0.486 0.001
C96.3 True histiocytic lymphoma
0.513 0.486 0.001
C96.2 Malignant mast cell tumour
0.513 0.486 0.001
C96.1 Malignant histiocytosis
0.513 0.486 0.001
C96.0 Letterer-Siwe disease
0.513 0.486 0.001
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E22.1 Hyperprolactinaemia
0.000 0.487 0.513
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.488 0.512
M08.9 Juvenile arthritis, unspecified
0.512 0.488 0.000
M08.8 Other juvenile arthritis
0.512 0.488 0.000
M08.4 Pauciarticular juvenile arthritis
0.512 0.488 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.512 0.488 0.000
M08.2 Juvenile arthritis with systemic onset
0.512 0.488 0.000
M08.1 Juvenile ankylosing spondylitis
0.512 0.488 0.000
M08.0 Juvenile rheumatoid arthritis
0.512 0.488 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.512 0.488 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.512 0.488 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.512 0.488 0.000
M09.0 Juvenile arthritis in psoriasis
0.512 0.488 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.512 0.488 0.000
M12.5 Traumatic arthropathy
0.512 0.488 0.000
M12.4 Intermittent hydrarthrosis
0.512 0.488 0.000
M12.3 Palindromic rheumatism
0.512 0.488 0.000
M12.2 Villonodular synovitis (pigmented)
0.512 0.488 0.000
M12.1 Kaschin-Beck disease
0.512 0.488 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.512 0.488 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.488 0.511
E45 Retarded development following protein-energy malnutrition
0.000 0.488 0.511
E43 Unspecified severe protein-energy malnutrition
0.000 0.488 0.511
E42 Marasmic kwashiorkor
0.000 0.488 0.511
E41 Nutritional marasmus
0.000 0.488 0.511
E40 Kwashiorkor
0.000 0.488 0.511
M06.48 Inflammatory polyarthropathy (Other)
0.510 0.490 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.510 0.490 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.510 0.490 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.510 0.490 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.510 0.490 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.510 0.490 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.510 0.490 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.510 0.490 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.491 0.509
E25.8 Other adrenogenital disorders
0.000 0.491 0.509
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.491 0.509
E30.9 Disorder of puberty, unspecified
0.000 0.491 0.509
E30.8 Other disorders of puberty
0.000 0.491 0.509
E30.1 Precocious puberty
0.000 0.491 0.509
E30.0 Delayed puberty
0.000 0.491 0.509
E31.9 Polyglandular dysfunction, unspecified
0.000 0.491 0.509
E31.8 Other polyglandular dysfunction
0.000 0.491 0.509
E31.1 Polyglandular hyperfunction
0.000 0.491 0.509
E31.0 Autoimmune polyglandular failure
0.000 0.491 0.509
E32.9 Disease of thymus, unspecified
0.000 0.491 0.509
E32.8 Other diseases of thymus
0.000 0.491 0.509
E32.1 Abscess of thymus
0.000 0.491 0.509
E32.0 Persistent hyperplasia of thymus
0.000 0.491 0.509
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.491 0.509
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.491 0.509
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.491 0.509

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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