TreeWAS – Variant ID: rs17577085

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.040	0.960	0.000
K90 Intestinal malabsorption	0.026	0.974	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.023	0.977	0.000
K90.8 Other intestinal malabsorption	0.020	0.980	0.000
K90.3 Pancreatic steatorrhoea	0.019	0.981	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.019	0.981	0.000
K90.1 Tropical sprue	0.019	0.981	0.000
K90.9 Intestinal malabsorption, unspecified	0.018	0.982	0.000
H25.1 Senile nuclear cataract	0.000	0.983	0.017
H34 Retinal vascular occlusions	0.016	0.984	0.000
H35.8 Other specified retinal disorders	0.016	0.984	0.000
H33.3 Retinal breaks without detachment	0.016	0.984	0.000
H35 Other retinal disorders	0.015	0.985	0.000
H34.8 Other retinal vascular occlusions	0.015	0.985	0.000
H35.9 Retinal disorder, unspecified	0.015	0.985	0.000
H30-H36 Disorders of choroid and retina	0.015	0.985	0.000
H33 Retinal detachments and breaks	0.015	0.985	0.000
H34.2 Other retinal artery occlusions	0.014	0.986	0.000
I12.0 Hypertensive renal disease with renal failure	0.014	0.986	0.000
D68 Other coagulation defects	0.000	0.986	0.014
H35.2 Other proliferative retinopathy	0.013	0.987	0.000
H33.2 Serous retinal detachment	0.013	0.987	0.000
D68.8 Other specified coagulation defects	0.000	0.987	0.013
D68.0 Von Willebrand's disease	0.000	0.987	0.013
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.987	0.013
H35.6 Retinal haemorrhage	0.012	0.988	0.000
D68.9 Coagulation defect, unspecified	0.000	0.988	0.012
H34.1 Central retinal artery occlusion	0.012	0.988	0.000
H35.5 Hereditary retinal dystrophy	0.012	0.988	0.000
H35.4 Peripheral retinal degeneration	0.012	0.988	0.000
H34.9 Retinal vascular occlusion, unspecified	0.011	0.988	0.000
H34.0 Transient retinal artery occlusion	0.011	0.988	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.989	0.011
H25 Senile cataract	0.000	0.989	0.011
H35.1 Retinopathy of prematurity	0.011	0.989	0.000
D68.5 Primary Thrombophilia	0.000	0.989	0.011
R30.0 Dysuria	0.011	0.989	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.011	0.989	0.000
H30 Chorioretinal inflammation	0.011	0.989	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.011	0.989	0.000
H25.8 Other senile cataract	0.000	0.989	0.011
H25.0 Senile incipient cataract	0.000	0.989	0.011
H31 Other disorders of choroid	0.010	0.989	0.000
D68.6 Other Thrombophilia	0.000	0.990	0.010
I12 Hypertensive renal disease	0.010	0.990	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.010	0.990	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.990	0.010
D68.1 Hereditary factor XI deficiency	0.000	0.990	0.010
H33.5 Other retinal detachments	0.010	0.990	0.000
H33.4 Traction detachment of retina	0.010	0.990	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.010	0.990	0.000
H35.7 Separation of retinal layers	0.009	0.990	0.000
I12.9 Hypertensive renal disease without renal failure	0.009	0.990	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.009	0.991	0.000
L08 Other local infections of skin and subcutaneous tissue	0.009	0.991	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.009	0.991	0.000
H25.2 Senile cataract, morgagnian type	0.000	0.992	0.008
L60.8 Other nail disorders	0.008	0.992	0.000
H35.0 Background retinopathy and retinal vascular changes	0.008	0.992	0.000
H33.1 Retinoschisis and retinal cysts	0.008	0.992	0.000
H30.9 Chorioretinal inflammation, unspecified	0.008	0.992	0.000
H30.8 Other chorioretinal inflammations	0.008	0.992	0.000
H30.2 Posterior cyclitis	0.008	0.992	0.000
H30.1 Disseminated chorioretinal inflammation	0.008	0.992	0.000
H30.0 Focal chorioretinal inflammation	0.008	0.992	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.008	0.992	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
H31.9 Disorder of choroid, unspecified	0.008	0.992	0.000
H31.8 Other specified disorders of choroid	0.008	0.992	0.000
H31.4 Choroidal detachment	0.008	0.992	0.000
H31.3 Choroidal haemorrhage and rupture	0.008	0.992	0.000
H31.2 Hereditary choroidal dystrophy	0.008	0.992	0.000
H31.1 Choroidal degeneration	0.008	0.992	0.000
H33.0 Retinal detachment with retinal break	0.008	0.992	0.000
I60 Subarachnoid haemorrhage	0.008	0.992	0.000
H31.0 Chorioretinal scars	0.007	0.993	0.000
H36 Retinal disorders in diseases classified elsewhere	0.007	0.993	0.000
H40.9 Glaucoma, unspecified	0.000	0.993	0.007
L60 Nail disorders	0.007	0.993	0.000
I60-I69 Cerebrovascular diseases	0.007	0.993	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.007	0.993	0.000
I61 Intracerebral haemorrhage	0.007	0.993	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.007	0.993	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.007	0.993	0.000
L60.9 Nail disorder, unspecified	0.007	0.993	0.000
L60.3 Nail dystrophy	0.007	0.993	0.000
L08.1 Erythrasma	0.006	0.993	0.000
L08.0 Pyoderma	0.006	0.993	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.007	0.993	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.006	0.994	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.006	0.994	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.006	0.994	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.006	0.994	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.006	0.994	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.006	0.994	0.000
L60.0 Ingrowing nail	0.006	0.994	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.006	0.994	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.006	0.994	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.006	0.994	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.006	0.994	0.000
I74 Arterial embolism and thrombosis	0.006	0.994	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.006	0.994	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.006	0.994	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.006	0.994	0.000
I69 Sequelae of cerebrovascular disease	0.006	0.994	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.006	0.994	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.005	0.994	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.006	0.994	0.000
L60.5 Yellow nail syndrome	0.005	0.994	0.000
L60.4 Beau's lines	0.005	0.994	0.000
L60.1 Onycholysis	0.005	0.994	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.005	0.994	0.000
T88.5 Other complications of anaesthesia	0.005	0.994	0.000
Z96.6 Presence of orthopaedic joint implants	0.006	0.994	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.005	0.995	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.005	0.995	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.005	0.995	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.005	0.995	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.005	0.995	0.000
T88.9 Complication of surgical and medical care, unspecified	0.005	0.995	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.005	0.995	0.000
T88.2 Shock due to anaesthesia	0.005	0.995	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.005	0.995	0.000
T88.0 Infection following immunisation	0.005	0.995	0.000
K90-K93 Other diseases of the digestive system	0.005	0.995	0.000
I65.2 Occlusion and stenosis of carotid artery	0.005	0.995	0.000
I61.8 Other intracerebral haemorrhage	0.005	0.995	0.000
L60.2 Onychogryphosis	0.005	0.995	0.000
Z74.0 Reduced mobility	0.005	0.995	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.005	0.995	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.005	0.995	0.000
R30 Pain associated with micturition	0.005	0.995	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.005	0.995	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.005	0.995	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.005	0.995	0.000
I65.1 Occlusion and stenosis of basilar artery	0.005	0.995	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.005	0.995	0.000
I60.8 Other subarachnoid haemorrhage	0.005	0.995	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.995	0.005
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.005	0.995	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.004	0.995	0.000
I74.8 Embolism and thrombosis of other arteries	0.004	0.996	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.004	0.996	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.004	0.996	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.004	0.996	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.004	0.996	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.004	0.996	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.004	0.996	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.004	0.996	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.004	0.996	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.004	0.996	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.004	0.996	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.004	0.996	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
I68.0 Cerebral amyloid angiopathy	0.004	0.996	0.000
T88.4 Failed or difficult intubation	0.004	0.996	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.004	0.996	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.004	0.996	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.004	0.996	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.004	0.996	0.000
K92.9 Disease of digestive system, unspecified	0.004	0.996	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
D66 Hereditary factor VIII deficiency	0.000	0.996	0.004
K92 Other diseases of digestive system	0.004	0.996	0.000
I69.3 Sequelae of cerebral infarction	0.004	0.996	0.000
L05.9 Pilonidal cyst without abscess	0.004	0.996	0.000
K92.1 Melaena	0.004	0.996	0.000
I67 Other cerebrovascular diseases	0.004	0.996	0.000
Z74 Problems related to care-provider dependency	0.004	0.996	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.004	0.996	0.000
R30.1 Vesical tenesmus	0.004	0.996	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.004	0.996	0.000
I71.0 Dissection of aorta [any part]	0.004	0.996	0.000
L05 Pilonidal cyst	0.004	0.996	0.000
R30.9 Painful micturition, unspecified	0.004	0.996	0.000
I62 Other nontraumatic intracranial haemorrhage	0.003	0.996	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.004	0.996	0.000
T43.2 Other and unspecified antidepressants	0.004	0.996	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.004	0.996	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.004	0.996	0.000
D67 Hereditary factor IX deficiency	0.000	0.996	0.004
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.996	0.004
T45.5 Anticoagulants	0.004	0.996	0.000
I67.1 Cerebral aneurysm, nonruptured	0.004	0.996	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.003	0.996	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.003	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
L04 Acute lymphadenitis	0.003	0.997	0.000
M79.63 Pain in limb (Forearm)	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.003	0.997	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
I67.2 Cerebral atherosclerosis	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.003	0.997	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.003	0.997	0.000
K93.1 Megacolon in Chagas' disease	0.003	0.997	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.003	0.997	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
Z74.1 Need for assistance with personal care	0.003	0.997	0.000
L04.9 Acute lymphadenitis, unspecified	0.003	0.997	0.000
Z74.3 Need for continuous supervision	0.003	0.997	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.003	0.997	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.003	0.997	0.000
I67.5 Moyamoya disease	0.003	0.997	0.000
I67.4 Hypertensive encephalopathy	0.003	0.997	0.000
I67.3 Progressive vascular leukoencephalopathy	0.003	0.997	0.000
L05.0 Pilonidal cyst with abscess	0.003	0.997	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.003	0.997	0.000
R59.9 Enlarged lymph nodes, unspecified	0.000	0.997	0.003
Z74.8 Other problems related to care-provider dependency	0.003	0.997	0.000
M79.60 Pain in limb (Multiple sites)	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
M79.64 Pain in limb (Hand)	0.003	0.997	0.000
I62.1 Nontraumatic extradural haemorrhage	0.003	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.003	0.997	0.000
F20.9 Schizophrenia, unspecified	0.003	0.997	0.000
M23.8 Other internal derangements of knee	0.003	0.997	0.000
L01 Impetigo	0.003	0.997	0.000
L00 Staphylococcal scalded skin syndrome	0.003	0.997	0.000
O32.8 Maternal care for other malpresentation of foetus	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.003	0.997	0.000
G93.3 Postviral fatigue syndrome	0.000	0.997	0.003
I10-I15 Hypertensive diseases	0.003	0.997	0.000
M79.62 Pain in limb (Upper arm)	0.003	0.997	0.000
L04.0 Acute lymphadenitis of face, head and neck	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
K92.8 Other specified diseases of digestive system	0.003	0.997	0.000
M79.6 Pain in limb	0.003	0.997	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.003	0.997	0.000
O32.1 Maternal care for breech presentation	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
L60-L75 Disorders of skin appendages	0.003	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.003	0.997	0.000
T78.2 Anaphylactic shock, unspecified	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.003
L04.8 Acute lymphadenitis of other sites	0.003	0.997	0.000
L04.3 Acute lymphadenitis of lower limb	0.003	0.997	0.000
L04.2 Acute lymphadenitis of upper limb	0.003	0.997	0.000
L04.1 Acute lymphadenitis of trunk	0.003	0.997	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.002	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
M79.69 Pain in limb (Site unspecified)	0.003	0.997	0.000
I71 Aortic aneurysm and dissection	0.003	0.997	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.000	0.997	0.003
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.003	0.997	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.003	0.997	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.997	0.000
T42.1 Iminostilbenes	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.997	0.000
T45.4 Iron and its compounds	0.002	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.997	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
M79.68 Pain in limb (Other)	0.002	0.997	0.000
L65 Other nonscarring hair loss	0.002	0.997	0.000
L85.8 Other specified epidermal thickening	0.003	0.997	0.000
T36.0 Penicillins	0.002	0.997	0.000
F20 Schizophrenia	0.003	0.997	0.000
K92.0 Haematemesis	0.002	0.997	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
T38.5 Other oestrogens and progestogens	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
T51.0 Ethanol	0.002	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.002	0.998	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.002	0.998	0.000
F43.2 Adjustment disorders	0.002	0.998	0.000
I11 Hypertensive heart disease	0.002	0.998	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.002	0.998	0.000
L65.9 Nonscarring hair loss, unspecified	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
Z75.5 Holiday relief care	0.002	0.998	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.002	0.998	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.002	0.998	0.000
L01.1 Impetiginisation of other dermatoses	0.002	0.998	0.000
L01.0 Impetigo [any organism] [any site]	0.002	0.998	0.000
I15 Secondary hypertension	0.002	0.998	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.002	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T36.3 Macrolides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
I13 Hypertensive heart and renal disease	0.002	0.998	0.000
H11.0 Pterygium	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
L70 Acne	0.002	0.998	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.002	0.998	0.000
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
M79.61 Pain in limb (Shoulder region)	0.002	0.998	0.000
H83.0 Labyrinthitis	0.002	0.998	0.000
R59.1 Generalised enlarged lymph nodes	0.000	0.998	0.002
H11.3 Conjunctival haemorrhage	0.000	0.998	0.002
H40 Glaucoma	0.000	0.998	0.002
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
L75 Apocrine sweat disorders	0.002	0.998	0.000
L74 Eccrine sweat disorders	0.002	0.998	0.000
L68 Hypertrichosis	0.002	0.998	0.000
L67 Hair colour and hair shaft abnormalities	0.002	0.998	0.000
L66 Cicatricial alopecia [scarring hair loss]	0.002	0.998	0.000
L64 Androgenic alopecia	0.002	0.998	0.000
L63 Alopecia areata	0.002	0.998	0.000
L62 Nail disorders in diseases classified elsewhere	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T37.5 Antiviral drugs	0.002	0.998	0.000
T37.4 Anthelminthics	0.002	0.998	0.000
T37.3 Other antiprotozoal drugs	0.002	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T37.1 Antimycobacterial drugs	0.002	0.998	0.000
T37.0 Sulphonamides	0.002	0.998	0.000
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
T48.4 Expectorants	0.002	0.998	0.000
T48.3 Antitussives	0.002	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
T48.0 Oxytocic drugs	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.002	0.998	0.000
H11 Other disorders of conjunctiva	0.000	0.998	0.002
Q61 Cystic kidney disease	0.002	0.998	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.002	0.998	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.002	0.998	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.002	0.998	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.002	0.998	0.000
I72.3 Aneurysm of iliac artery	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
W19.4 Street and highway	0.002	0.998	0.000
I70 Atherosclerosis	0.002	0.998	0.000
L83 Acanthosis nigricans	0.002	0.998	0.000
T66-T78 Other and unspecified effects of external causes	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.998	0.002
O32.4 Maternal care for high head at term	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
Z75 Problems related to medical facilities and other health care	0.002	0.998	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
I15.9 Seconday hypertension, unspecified	0.002	0.998	0.000
L65.8 Other specified nonscarring hair loss	0.002	0.998	0.000
L65.2 Alopecia mucinosa	0.002	0.998	0.000
L65.1 Anagen effluvium	0.002	0.998	0.000
L65.0 Telogen effluvium	0.002	0.998	0.000
O32.3 Maternal care for face, brow and chin presentation	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.002	0.998	0.000
F20.8 Other schizophrenia	0.002	0.998	0.000
F20.6 Simple schizophrenia	0.002	0.998	0.000
F20.5 Residual schizophrenia	0.002	0.998	0.000
F20.4 Postschizophrenic depression	0.002	0.998	0.000
F20.3 Undifferentiated schizophrenia	0.002	0.998	0.000
F20.2 Catatonic schizophrenia	0.002	0.998	0.000
F20.1 Hebephrenic schizophrenia	0.002	0.998	0.000
H40.5 Glaucoma secondary to other eye disorders	0.000	0.998	0.002
Q61.0 Congenital single renal cyst	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
H11.9 Disorder of conjunctiva, unspecified	0.000	0.998	0.002
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.002	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.002	0.998	0.000
S43.0 Dislocation of shoulder joint	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
L70.0 Acne vulgaris	0.002	0.998	0.000
D05.7 Other carcinoma in situ of breast	0.002	0.998	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.002	0.998	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.002	0.998	0.000
T78.3 Angioneurotic oedema	0.002	0.998	0.000
L28 Lichen simplex chronicus and prurigo	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.002	0.998	0.000
H36.0 Diabetic retinopathy	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.998	0.002
I15.8 Other secondary hypertension	0.002	0.998	0.000
I15.2 Hypertension secondary to endocrine disorders	0.002	0.998	0.000
I15.0 Renovascular hypertension	0.002	0.998	0.000
I72 Other aneurysm	0.002	0.998	0.000
L85 Other epidermal thickening	0.002	0.998	0.000
T51 Toxic effect of alcohol	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
H11.1 Conjunctival degenerations and deposits	0.000	0.998	0.002
I13.9 Hypertensive heart and renal disease, unspecified	0.002	0.998	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.002	0.998	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.002	0.998	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.002	0.998	0.000
L70.9 Acne, unspecified	0.002	0.998	0.000
L70.8 Other acne	0.002	0.998	0.000
L70.5 Acne excoriee des jeunes filles	0.002	0.998	0.000
L70.4 Infantile acne	0.002	0.998	0.000
L70.3 Acne tropica	0.002	0.998	0.000
L70.2 Acne varioliformis	0.002	0.998	0.000
L70.1 Acne conglobata	0.002	0.998	0.000
T78.9 Adverse effect, unspecified	0.002	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.002	0.998	0.000
E27 Other disorders of adrenal gland	0.000	0.998	0.002
T21 Burn and corrosion of trunk	0.002	0.998	0.000
H11.8 Other specified disorders of conjunctiva	0.000	0.998	0.002
H40.1 Primary open-angle glaucoma	0.000	0.998	0.002
O32.9 Maternal care for malpresentation of foetus, unspecified	0.002	0.998	0.000
O32.6 Maternal care for compound presentation	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations