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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17596719
log Bayes Factor = 12.5999
Chromosome 6   position 26,097,194  (GRCh37) Explore rs17596719 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
E83 Disorders of mineral metabolism
0.000 0.889 0.111
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.920 0.080
E83.8 Other disorders of mineral metabolism
0.000 0.920 0.080
E83.2 Disorders of zinc metabolism
0.000 0.920 0.080
E83.0 Disorders of copper metabolism
0.000 0.920 0.080
E83.3 Disorders of phosphorus metabolism
0.000 0.921 0.079
E83.4 Disorders of magnesium metabolism
0.000 0.952 0.047
E11.9 Without complications
0.000 0.963 0.037
E11 Non-insulin-dependent diabetes mellitus
0.000 0.971 0.029
E11.2 With renal complications
0.000 0.975 0.025
E11.1 With ketoacidosis
0.000 0.976 0.024
E10 Insulin-dependent diabetes mellitus
0.000 0.977 0.023
E10-E14 Diabetes mellitus
0.000 0.977 0.023
K59.8 Other specified functional intestinal disorders
0.023 0.977 0.000
E11.6 With other specified complications
0.000 0.977 0.023
E11.8 With unspecified complications
0.000 0.978 0.022
K43.9 Ventral hernia without obstruction or gangrene
0.021 0.979 0.000
E83.5 Disorders of calcium metabolism
0.000 0.979 0.021
E11.5 With peripheral circulatory complications
0.000 0.979 0.021
E11.7 With multiple complications
0.000 0.979 0.021
E10.1 With ketoacidosis
0.000 0.979 0.021
E10.9 Without complications
0.000 0.979 0.021
E10.3 With ophthalmic complications
0.000 0.979 0.021
I27.0 Primary pulmonary hypertension
0.000 0.981 0.019
E11.0 With coma
0.000 0.981 0.019
E10.5 With peripheral circulatory complications
0.000 0.981 0.019
E10.0 With coma
0.000 0.982 0.018
E11.3 With ophthalmic complications
0.000 0.982 0.018
E10.7 With multiple complications
0.000 0.983 0.017
E12 Malnutrition-related diabetes mellitus
0.000 0.983 0.017
E14 Unspecified diabetes mellitus
0.000 0.983 0.016
E10.6 With other specified complications
0.000 0.984 0.016
E10.4 With neurological complications
0.000 0.984 0.016
K90.0 Coeliac disease
0.000 0.984 0.016
E10.8 With unspecified complications
0.000 0.985 0.015
E10.2 With renal complications
0.000 0.986 0.014
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.014 0.986 0.000
E13 Other specified diabetes mellitus
0.000 0.986 0.014
J38.7 Other diseases of larynx
0.014 0.986 0.000
E14.9 Without complications
0.000 0.986 0.014
G40.9 Epilepsy, unspecified
0.000 0.986 0.014
I27 Other pulmonary heart diseases
0.000 0.987 0.013
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.013 0.987 0.000
E14.3 With ophthalmic complications
0.000 0.987 0.013
E12.9 Without complications
0.000 0.988 0.012
E12.8 With unspecified complications
0.000 0.988 0.012
E12.7 With multiple complications
0.000 0.988 0.012
E12.6 With other specified complications
0.000 0.988 0.012
E12.5 With peripheral circulatory complications
0.000 0.988 0.012
E12.4 With neurological complications
0.000 0.988 0.012
E12.3 With ophthalmic complications
0.000 0.988 0.012
E12.2 With renal complications
0.000 0.988 0.012
E12.1 With ketoacidosis
0.000 0.988 0.012
E12.0 With coma
0.000 0.988 0.012
E14.7 With multiple complications
0.000 0.988 0.012
E14.6 With other specified complications
0.000 0.988 0.012
E14.5 With peripheral circulatory complications
0.000 0.988 0.012
E14.4 With neurological complications
0.000 0.988 0.012
E14.2 Withrenal complications
0.000 0.988 0.012
E14.0 With coma
0.000 0.988 0.012
G40 Epilepsy
0.000 0.988 0.012
T39.1 4-Aminophenol derivatives
0.012 0.988 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.012 0.988 0.000
I27.2 Other secondary pulmonary hypertension
0.000 0.988 0.012
J38.5 Laryngeal spasm
0.012 0.988 0.000
I27.8 Other specified pulmonary heart diseases
0.000 0.989 0.011
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.000 0.989 0.011
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.011 0.989 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.011 0.989 0.000
E14.1 With ketoacidosis
0.000 0.989 0.011
Q80-Q89 Other congenital malformations
0.011 0.989 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.000 0.990 0.010
T36-T50 Poisoning by drugs, medicaments and biological substances
0.010 0.990 0.000
E13.8 With unspecified complications
0.000 0.990 0.010
E13.7 With multiple complications
0.000 0.990 0.010
E13.6 With other specified complications
0.000 0.990 0.010
E13.5 With peripheral circulatory complications
0.000 0.990 0.010
E13.4 With neurological complications
0.000 0.990 0.010
E13.3 With ophthalmic complications
0.000 0.990 0.010
E13.2 With renal complications
0.000 0.990 0.010
E13.1 With ketoacidosis
0.000 0.990 0.010
E13.0 With coma
0.000 0.990 0.010
J38.6 Stenosis of larynx
0.010 0.990 0.000
J38.4 Oedema of larynx
0.010 0.990 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.000 0.990 0.010
J38.2 Nodules of vocal cords
0.010 0.990 0.000
S00.9 Superficial injury of head, part unspecified
0.010 0.990 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.010 0.990 0.000
E14.8 With unspecified complications
0.000 0.990 0.010
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.010 0.990 0.000
I27.1 Kyphoscoliotic heart disease
0.000 0.990 0.010
T39.4 Antirheumatics, not elsewhere classified
0.010 0.990 0.000
T39.2 Pyrazolone derivatives
0.010 0.990 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.010 0.990 0.000
T39.0 Salicylates
0.009 0.990 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.009 0.991 0.000
I27.9 Pulmonary heart disease, unspecified
0.000 0.991 0.009
Q66 Congenital deformities of feet
0.009 0.991 0.000
Q50-Q56 Congenital malformations of genital organs
0.009 0.991 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.009 0.991 0.000
Q00-Q07 Congenital malformations of the nervous system
0.009 0.991 0.000
Q85 Phakomatoses, not elsewhere classified
0.009 0.991 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.000 0.991 0.009
Q82 Other congenital malformations of skin
0.009 0.991 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.009 0.991 0.000
G40.8 Other epilepsy
0.000 0.991 0.009
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.009 0.991 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.009 0.991 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.000 0.991 0.009
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.000 0.991 0.009
Q66.7 Pes cavus
0.009 0.991 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.009 0.991 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.009 0.991 0.000
Q60-Q64 Congenital malformations of the urinary system
0.009 0.991 0.000
T36 Poisoning by systemic antibiotics
0.009 0.991 0.000
Q76 Congenital malformations of spine and bony thorax
0.008 0.991 0.000
Q83 Congenital malformations of breast
0.008 0.991 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.000 0.991 0.009
T43.0 Tricyclic and tetracyclic antidepressants
0.009 0.991 0.000
Q61 Cystic kidney disease
0.008 0.992 0.000
Q43 Other congenital malformations of intestine
0.008 0.992 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.008 0.992 0.000
Q55 Other congenital malformations of male genital organs
0.008 0.992 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.008 0.992 0.000
Q66.6 Other congenital valgus deformities of feet
0.008 0.992 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.008 0.992 0.000
K90 Intestinal malabsorption
0.000 0.992 0.008
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.008 0.992 0.000
Q35-Q37 Cleft lip and cleft palate
0.008 0.992 0.000
Q43.0 Meckel's diverticulum
0.008 0.992 0.000
Q61.0 Congenital single renal cyst
0.008 0.992 0.000
Q82.5 Congenital nonneoplastic naevus
0.008 0.992 0.000
J38.3 Other diseases of vocal cords
0.008 0.992 0.000
G40.5 Special epileptic syndromes
0.000 0.992 0.008
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.008 0.992 0.000
Q84 Other congenital malformations of integument
0.008 0.992 0.000
Q81 Epidermolysis bullosa
0.008 0.992 0.000
Q80 Congenital ichthyosis
0.008 0.992 0.000
Q07 Other congenital malformations of nervous system
0.008 0.992 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.008 0.992 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.008 0.992 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.008 0.992 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.008 0.992 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.008 0.992 0.000
T42.4 Benzodiazepines
0.008 0.992 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.008 0.992 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.008 0.992 0.000
Q85.8 Other phakomatoses, not elsewhere classified
0.008 0.992 0.000
Q27 Other congenital malformations of peripheral vascular system
0.008 0.992 0.000
J38.0 Paralysis of vocal cords and larynx
0.008 0.992 0.000
Q31 Congenital malformations of larynx
0.007 0.992 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.008 0.992 0.000
Q28 Other congenital malformations of circulatory system
0.007 0.993 0.000
Q78 Other osteochondrodysplasias
0.007 0.993 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.007 0.993 0.000
Q75 Other congenital malformations of skull and face bones
0.007 0.993 0.000
Q74 Other congenital malformations of limb(s)
0.007 0.993 0.000
Q73 Reduction defects of unspecified limb
0.007 0.993 0.000
Q72 Reduction defects of lower limb
0.007 0.993 0.000
Q71 Reduction defects of upper limb
0.007 0.993 0.000
Q70 Syndactyly
0.007 0.993 0.000
Q69 Polydactyly
0.007 0.993 0.000
Q68 Other congenital musculoskeletal deformities
0.007 0.993 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.007 0.993 0.000
Q52 Other congenital malformations of female genitalia
0.007 0.993 0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified
0.007 0.993 0.000
E13.9 Without complications
0.000 0.993 0.007
Q76.0 Spina bifida occulta
0.007 0.993 0.000
T36.0 Penicillins
0.007 0.993 0.000
Q51 Congenital malformations of uterus and cervix
0.007 0.993 0.000
Q55.6 Other congenital malformations of penis
0.007 0.993 0.000
Q05 Spina bifida
0.007 0.993 0.000
Q83.1 Accessory breast
0.007 0.993 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.007 0.993 0.000
T43.2 Other and unspecified antidepressants
0.007 0.993 0.000
S32.50 Fracture of pubis (closed)
0.007 0.993 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.007 0.993 0.000
Q45 Other congenital malformations of digestive system
0.007 0.993 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.007 0.993 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.007 0.993 0.000
Q40 Other congenital malformations of upper alimentary tract
0.007 0.993 0.000
Q87.4 Marfan's syndrome
0.007 0.993 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.007 0.993 0.000
E11.4 With neurological complications
0.000 0.993 0.007
Q76.1 Klippel-Feil syndrome
0.007 0.993 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.007 0.993 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.007 0.993 0.000
T42.3 Barbiturates
0.007 0.993 0.000
T42.2 Succinimides and oxazolidinediones
0.007 0.993 0.000
T42.0 Hydantoin derivatives
0.007 0.993 0.000
Q25 Congenital malformations of great arteries
0.007 0.993 0.000
Q53 Undescended testicle
0.007 0.993 0.000
Q66.9 Congenital deformity of feet, unspecified
0.007 0.993 0.000
Q66.5 Congenital pes planus
0.007 0.993 0.000
Q66.4 Talipes calcaneovalgus
0.007 0.993 0.000
Q66.3 Other congenital varus deformities of feet
0.007 0.993 0.000
Q66.2 Metatarsus varus
0.007 0.993 0.000
Q66.1 Talipes calcaneovarus
0.007 0.993 0.000
Q66.0 Talipes equinovarus
0.007 0.993 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.007 0.993 0.000
Q61.2 Polycystic kidney, adult type
0.007 0.993 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.007 0.993 0.000
T43.9 Psychotropic drug, unspecified
0.007 0.993 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.007 0.993 0.000
T43.6 Psychostimulants with abuse potential
0.007 0.993 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.007 0.993 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.007 0.993 0.000
Q06 Other congenital malformations of spinal cord
0.007 0.993 0.000
Q04 Other congenital malformations of brain
0.007 0.993 0.000
Q03 Congenital hydrocephalus
0.007 0.993 0.000
Q01 Encephalocele
0.007 0.993 0.000
Q00 Anencephaly and similar malformations
0.007 0.993 0.000
Q02 Microcephaly
0.007 0.993 0.000
Q85.1 Tuberous sclerosis
0.007 0.993 0.000
Q89 Other congenital malformations, not elsewhere classified
0.007 0.993 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.007 0.993 0.000
Q82.8 Other specified congenital malformations of skin
0.007 0.993 0.000
Q85.9 Phakomatosis, unspecified
0.007 0.993 0.000
Q07.0 Arnold-Chiari syndrome
0.007 0.993 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.007 0.993 0.000
Q82.9 Congenital malformation of skin, unspecified
0.007 0.993 0.000
Q82.4 Ectodermal dysplasia (anhidrotic)
0.007 0.993 0.000
Q82.3 Incontinentia pigmenti
0.007 0.993 0.000
Q82.2 Mastocytosis
0.007 0.993 0.000
Q82.1 Xeroderma pigmentosum
0.007 0.993 0.000
Q82.0 Hereditary lymphoedema
0.007 0.993 0.000
Q61.9 Cystic kidney disease, unspecified
0.007 0.993 0.000
Q61.5 Medullary cystic kidney
0.007 0.993 0.000
Q24 Other congenital malformations of heart
0.007 0.993 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.007 0.993 0.000
T42.1 Iminostilbenes
0.007 0.993 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.007 0.993 0.000
Q34 Other congenital malformations of respiratory system
0.007 0.993 0.000
Q33 Congenital malformations of lung
0.007 0.993 0.000
Q32 Congenital malformations of trachea and bronchus
0.007 0.993 0.000
Q30 Congenital malformations of nose
0.007 0.993 0.000
Q39 Congenital malformations of oesophagus
0.007 0.993 0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes
0.006 0.993 0.000
Q87.3 Congenital malformation syndromes involving early overgrowth
0.006 0.993 0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs
0.006 0.993 0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature
0.006 0.993 0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance
0.006 0.993 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.007 0.993 0.000
Q26 Congenital malformations of great veins
0.007 0.993 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.007 0.993 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.007 0.993 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.993 0.007
Q31.0 Web of larynx
0.006 0.993 0.000
Q65 Congenital deformities of hip
0.006 0.993 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.006 0.993 0.000
T50.8 Diagnostic agents
0.006 0.993 0.000
T50.7 Analeptics and opioid receptor antagonists
0.006 0.993 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.006 0.993 0.000
T50.5 Appetite depressants
0.006 0.993 0.000
T50.4 Drugs affecting uric acid metabolism
0.006 0.993 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.006 0.993 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.006 0.993 0.000
T50.1 Loop [high-ceiling] diuretics
0.006 0.993 0.000
T50.0 Mineralocorticoids and their antagonists
0.006 0.993 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.006 0.993 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.006 0.993 0.000
Q64 Other congenital malformations of urinary system
0.006 0.994 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.006 0.994 0.000
Q28.0 Arteriovenous malformation of precerebral vessels
0.006 0.994 0.000
T36.9 Systemic antibiotic, unspecified
0.006 0.994 0.000
T36.8 Other systemic antibiotics
0.006 0.994 0.000
T36.7 Antifungal antibiotics, systemically used
0.006 0.994 0.000
T36.6 Rifamycins
0.006 0.994 0.000
T36.5 Aminoglycosides
0.006 0.994 0.000
T36.4 Tetracyclines
0.006 0.994 0.000
T36.3 Macrolides
0.006 0.994 0.000
T36.2 Chloramphenicol group
0.006 0.994 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.006 0.994 0.000
Q76.9 Congenital malformation of bony thorax, unspecified
0.006 0.994 0.000
Q76.8 Other congenital malformations of bony thorax
0.006 0.994 0.000
Q76.7 Congenital malformation of sternum
0.006 0.994 0.000
Q76.6 Other congenital malformations of ribs
0.006 0.994 0.000
Q76.5 Cervical rib
0.006 0.994 0.000
Q76.3 Congenital scoliosis due to congenital bony malformation
0.006 0.994 0.000
Q76.2 Congenital spondylolisthesis
0.006 0.994 0.000
Q55.2 Other congenital malformations of testis and scrotum
0.006 0.994 0.000
Q83.9 Congenital malformation of breast, unspecified
0.006 0.994 0.000
Q83.3 Accessory nipple
0.006 0.994 0.000
Q83.2 Absent nipple
0.006 0.994 0.000
Q83.0 Congenital absence of breast with absent nipple
0.006 0.994 0.000
Q38.7 Pharyngeal pouch
0.006 0.994 0.000
Q54 Hypospadias
0.006 0.994 0.000
Q27.8 Other specified congenital malformations of peripheral vascular system
0.006 0.994 0.000
Q27.3 Peripheral arteriovenous malformation
0.006 0.994 0.000
Q61.8 Other cystic kidney diseases
0.006 0.994 0.000
Q61.4 Renal dysplasia
0.006 0.994 0.000
Q61.1 Polycystic kidney, infantile type
0.006 0.994 0.000
Q66.8 Other congenital deformities of feet
0.006 0.994 0.000
T46.1 Calcium-channel blockers
0.006 0.994 0.000
Q83.8 Other congenital malformations of breast
0.006 0.994 0.000
Q43.7 Persistent cloaca
0.006 0.994 0.000
Q43.6 Congenital fistula of rectum and anus
0.006 0.994 0.000
Q43.5 Ectopic anus
0.006 0.994 0.000
Q43.4 Duplication of intestine
0.006 0.994 0.000
Q43.2 Other congenital functional disorders of colon
0.006 0.994 0.000
Q43.1 Hirschsprung's disease
0.006 0.994 0.000
S32.5 Fracture of pubis
0.006 0.994 0.000
Q43.3 Congenital malformations of intestinal fixation
0.006 0.994 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.006 0.994 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.006 0.994 0.000
T47.7 Emetics
0.006 0.994 0.000
T47.6 Antidiarrhoeal drugs
0.006 0.994 0.000
T47.5 Digestants
0.006 0.994 0.000
T47.4 Other laxatives
0.006 0.994 0.000
T47.3 Saline and osmotic laxatives
0.006 0.994 0.000
T47.2 Stimulant laxatives
0.006 0.994 0.000
T47.0 Histamine H(2)-receptor antagonists
0.006 0.994 0.000
Q23 Congenital malformations of aortic and mitral valves
0.006 0.994 0.000
Q55.9 Congenital malformation of male genital organ, unspecified
0.006 0.994 0.000
Q55.8 Other specified congenital malformations of male genital organs
0.006 0.994 0.000
Q55.5 Congenital absence and aplasia of penis
0.006 0.994 0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate
0.006 0.994 0.000
Q55.3 Atresia of vas deferens
0.006 0.994 0.000
Q55.1 Hypoplasia of testis and scrotum
0.006 0.994 0.000
Q55.0 Absence and aplasia of testis
0.006 0.994 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.006 0.994 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.006 0.994 0.000
T46.7 Peripheral vasodilators
0.006 0.994 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.006 0.994 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.006 0.994 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.006 0.994 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.006 0.994 0.000
Q17 Other congenital malformations of ear
0.006 0.994 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.006 0.994 0.000
Q15 Other congenital malformations of eye
0.006 0.994 0.000
Q14 Congenital malformations of posterior segment of eye
0.006 0.994 0.000
Q13 Congenital malformations of anterior segment of eye
0.006 0.994 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.006 0.994 0.000
K90.8 Other intestinal malabsorption
0.000 0.994 0.006
K90.3 Pancreatic steatorrhoea
0.000 0.994 0.006
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.994 0.006
K90.1 Tropical sprue
0.000 0.994 0.006
Q37 Cleft palate with cleft lip
0.006 0.994 0.000
Q36 Cleft lip
0.006 0.994 0.000
Q35 Cleft palate
0.006 0.994 0.000
Q99 Other chromosome abnormalities, not elsewhere classified
0.006 0.994 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.006 0.994 0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified
0.006 0.994 0.000
Q96 Turner's syndrome
0.006 0.994 0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified
0.006 0.994 0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified
0.006 0.994 0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified
0.006 0.994 0.000
Q91 Edwards' syndrome and Patau's syndrome
0.006 0.994 0.000
Q90 Down's syndrome
0.006 0.994 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.006 0.994 0.000
K43 Ventral hernia
0.006 0.994 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.994 0.006
Q52.5 Fusion of labia
0.006 0.994 0.000
L73.2 Hidradenitis suppurativa
0.000 0.994 0.006
T45.1 Antineoplastic and immunosuppressive drugs
0.006 0.994 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.994 0.006
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.006 0.994 0.000
Q80.9 Congenital ichthyosis, unspecified
0.006 0.994 0.000
Q80.8 Other congenital ichthyosis
0.006 0.994 0.000
Q80.4 Harlequin foetus
0.006 0.994 0.000
Q80.3 Congenital bullous ichthyosiform erythroderma
0.006 0.994 0.000
Q80.2 Lamellar ichthyosis
0.006 0.994 0.000
Q80.1 X-linked ichthyosis
0.006 0.994 0.000
Q80.0 Ichthyosis vulgaris
0.006 0.994 0.000
Q81.9 Epidermolysis bullosa, unspecified
0.006 0.994 0.000
Q81.8 Other epidermolysis bullosa
0.006 0.994 0.000
Q81.2 Epidermolysis bullosa dystrophica
0.006 0.994 0.000
Q81.1 Epidermolysis bullosa letalis
0.006 0.994 0.000
Q81.0 Epidermolysis bullosa simplex
0.006 0.994 0.000
Q84.9 Congenital malformation of integument, unspecified
0.006 0.994 0.000
Q84.8 Other specified congenital malformations of integument
0.006 0.994 0.000
Q84.6 Other congenital malformations of nails
0.006 0.994 0.000
Q84.5 Enlarged and hypertrophic nails
0.006 0.994 0.000
Q84.4 Congenital leukonychia
0.006 0.994 0.000
Q84.3 Anonychia
0.006 0.994 0.000
Q84.2 Other congenital malformations of hair
0.006 0.994 0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified
0.006 0.994 0.000
Q84.0 Congenital alopecia
0.006 0.994 0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes
0.006 0.994 0.000
Q86.2 Dysmorphism due to warfarin
0.006 0.994 0.000
Q86.1 Foetal hydantoin syndrome
0.006 0.994 0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)
0.006 0.994 0.000
Q07.9 Congenital malformation of nervous system, unspecified
0.006 0.994 0.000
Q07.8 Other specified congenital malformations of nervous system
0.006 0.994 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.006 0.994 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.006 0.994 0.000
T37.5 Antiviral drugs
0.006 0.994 0.000
T37.4 Anthelminthics
0.006 0.994 0.000
T37.3 Other antiprotozoal drugs
0.006 0.994 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.006 0.994 0.000
T37.1 Antimycobacterial drugs
0.006 0.994 0.000
T37.0 Sulphonamides
0.006 0.994 0.000
T41.5 Therapeutic gases
0.006 0.994 0.000
T41.4 Anaesthetic, unspecified
0.006 0.994 0.000
T41.3 Local anaesthetics
0.006 0.994 0.000
T41.2 Other and unspecified general anaesthetics
0.006 0.994 0.000
T41.1 Intravenous anaesthetics
0.006 0.994 0.000
T41.0 Inhaled anaesthetics
0.006 0.994 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.006 0.994 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.006 0.994 0.000
T48.5 Anti-common-cold drugs
0.006 0.994 0.000
T48.4 Expectorants
0.006 0.994 0.000
T48.3 Antitussives
0.006 0.994 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.006 0.994 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.006 0.994 0.000
T48.0 Oxytocic drugs
0.006 0.994 0.000
T49.9 Topical agent, unspecified
0.006 0.994 0.000
T49.8 Other topical agents
0.006 0.994 0.000
T49.7 Dental drugs, topically applied
0.006 0.994 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.006 0.994 0.000
T49.5 Ophthalmological drugs and preparations
0.006 0.994 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.006 0.994 0.000
T49.3 Emollients, demulcents and protectants
0.006 0.994 0.000
T49.2 Local astringents and local detergents
0.006 0.994 0.000
T49.1 Antipruritics
0.006 0.994 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.006 0.994 0.000
Q44.6 Cystic disease of liver
0.006 0.994 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.006 0.994 0.000
T45.8 Other primarily systemic and haematological agents
0.006 0.994 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.006 0.994 0.000
T45.6 Fibrinolysis-affecting drugs
0.006 0.994 0.000
T45.4 Iron and its compounds
0.006 0.994 0.000
T45.3 Enzymes, not elsewhere classified
0.006 0.994 0.000
T45.2 Vitamins, not elsewhere classified
0.006 0.994 0.000
Q38.8 Other congenital malformations of pharynx
0.006 0.994 0.000
Q38.6 Other congenital malformations of mouth
0.006 0.994 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.006 0.994 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.006 0.994 0.000
Q38.3 Other congenital malformations of tongue
0.006 0.994 0.000
Q38.2 Macroglossia
0.006 0.994 0.000
Q38.1 Ankyloglossia
0.006 0.994 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.006 0.994 0.000
T45.5 Anticoagulants
0.006 0.994 0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.006 0.994 0.000
Q27.4 Congenital phlebectasia
0.006 0.994 0.000
Q27.2 Other congenital malformations of renal artery
0.006 0.994 0.000
Q27.1 Congenital renal artery stenosis
0.006 0.994 0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery
0.006 0.994 0.000
Q05.9 Spina bifida, unspecified
0.006 0.994 0.000
Q12 Congenital lens malformations
0.006 0.994 0.000
Q25.1 Coarctation of aorta
0.006 0.994 0.000
Q11.1 Other anophthalmos
0.006 0.994 0.000
Q31.9 Congenital malformation of larynx, unspecified
0.005 0.994 0.000
Q31.8 Other congenital malformations of larynx
0.005 0.994 0.000
Q31.5 Congenital laryngomalacia
0.005 0.994 0.000
Q31.4 Congenital laryngeal stridor
0.005 0.994 0.000
Q31.3 Laryngocele
0.005 0.994 0.000
Q31.2 Laryngeal hypoplasia
0.005 0.994 0.000
Q31.1 Congenital subglottic stenosis
0.005 0.994 0.000
Q18 Other congenital malformations of face and neck
0.005 0.994 0.000
T45.0 Antiallergic and antiemetic drugs
0.006 0.994 0.000
Y45.0 Opioids and related analgesics
0.000 0.994 0.006
Q51.3 Bicornate uterus
0.005 0.994 0.000
Q79.8 Other congenital malformations of musculoskeletal system
0.005 0.994 0.000
Q28.9 Congenital malformation of circulatory system, unspecified
0.005 0.994 0.000
Q28.8 Other specified congenital malformations of circulatory system
0.005 0.994 0.000
Q28.3 Other malformations of cerebral vessels
0.005 0.994 0.000
Q28.1 Other malformations of precerebral vessels
0.005 0.994 0.000
Q68.8 Other specified congenital musculoskeletal deformities
0.005 0.994 0.000
Q68.5 Congenital bowing of long bones of leg, unspecified
0.005 0.994 0.000
Q68.4 Congenital bowing of tibia and fibula
0.005 0.994 0.000
Q68.3 Congenital bowing of femur
0.005 0.994 0.000
Q68.2 Congenital deformity of knee
0.005 0.994 0.000
Q68.1 Congenital deformity of hand
0.005 0.994 0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle
0.005 0.994 0.000
Q69.9 Polydactyly, unspecified
0.005 0.994 0.000
Q69.2 Accessory toe(s)
0.005 0.994 0.000
Q69.1 Accessory thumb(s)
0.005 0.994 0.000
Q69.0 Accessory finger(s)
0.005 0.994 0.000
Q70.9 Syndactyly, unspecified
0.005 0.994 0.000
Q70.4 Polysyndactyly
0.005 0.994 0.000
Q70.3 Webbed toes
0.005 0.994 0.000
Q70.2 Fused toes
0.005 0.994 0.000
Q70.1 Webbed fingers
0.005 0.994 0.000
Q70.0 Fused fingers
0.005 0.994 0.000
Q71.9 Reduction defect of upper limb, unspecified
0.005 0.994 0.000
Q71.8 Other reduction defects of upper limb(s)
0.005 0.994 0.000
Q71.6 Lobster-claw hand
0.005 0.994 0.000
Q71.5 Longitudinal reduction defect of ulna
0.005 0.994 0.000
Q71.4 Longitudinal reduction defect of radius
0.005 0.994 0.000
Q71.3 Congenital absence of hand and finger(s)
0.005 0.994 0.000
Q71.2 Congenital absence of both forearm and hand
0.005 0.994 0.000
Q71.1 Congenital absence of upper arm and forearm with hand present
0.005 0.994 0.000
Q71.0 Congenital complete absence of upper limb(s)
0.005 0.994 0.000
Q72.9 Reduction defect of lower limb, unspecified
0.005 0.994 0.000
Q72.8 Other reduction defects of lower limb(s)
0.005 0.994 0.000
Q72.7 Split foot
0.005 0.994 0.000
Q72.6 Longitudinal reduction defect of fibula
0.005 0.994 0.000
Q72.5 Longitudinal reduction defect of tibia
0.005 0.994 0.000
Q72.4 Longitudinal reduction defect of femur
0.005 0.994 0.000
Q72.3 Congenital absence of foot and toe(s)
0.005 0.994 0.000
Q72.2 Congenital absence of both lower leg and foot
0.005 0.994 0.000
Q72.1 Congenital absence of thigh and lower leg with foot present
0.005 0.994 0.000
Q72.0 Congenital complete absence of lower limb(s)
0.005 0.994 0.000
Q73.8 Other reduction defects of unspecified limb(s)
0.005 0.994 0.000
Q73.1 Phocomelia, unspecified limb(s)
0.005 0.994 0.000
Q73.0 Congenital absence of unspecified limb(s)
0.005 0.994 0.000
Q74.9 Unspecified congenital malformation of limb(s)
0.005 0.994 0.000
Q74.8 Other specified congenital malformations of limb(s)
0.005 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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