TreeWAS – Variant ID: rs17646665

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.002	0.998
E78.5 Hyperlipidaemia, unspecified	0.000	0.003	0.997
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.073	0.927
E78.6 Lipoprotein deficiency	0.000	0.285	0.715
E78.3 Hyperchylomicronaemia	0.000	0.285	0.715
E78.1 Pure hyperglyceridaemia	0.000	0.285	0.715
E78.4 Other hyperlipidaemia	0.000	0.285	0.715
E78.8 Other disorders of lipoprotein metabolism	0.000	0.311	0.689
E78.2 Mixed hyperlipidaemia	0.000	0.401	0.598
I25 Chronic ischaemic heart disease	0.000	0.412	0.588
I25.1 Atherosclerotic heart disease	0.000	0.415	0.585
I25.2 Old myocardial infarction	0.000	0.424	0.576
I20-I25 Ischaemic heart diseases	0.000	0.473	0.527
I10 Essential (primary) hypertension	0.000	0.478	0.522
I10-I15 Hypertensive diseases	0.000	0.483	0.517
I25.3 Aneurysm of heart	0.000	0.487	0.513
Chapter IX Diseases of the circulatory system	0.000	0.489	0.511
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.502	0.498
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.511	0.489
I74 Arterial embolism and thrombosis	0.000	0.516	0.484
I25.5 Ischaemic cardiomyopathy	0.000	0.529	0.471
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.530	0.470
I12 Hypertensive renal disease	0.000	0.556	0.444
I71 Aortic aneurysm and dissection	0.000	0.561	0.439
I25.6 Silent myocardial ischaemia	0.000	0.578	0.421
I25.4 Coronary artery aneurysm	0.000	0.578	0.421
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.578	0.421
I77 Other disorders of arteries and arterioles	0.000	0.593	0.407
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.600	0.399
I20 Angina pectoris	0.000	0.604	0.396
I73 Other peripheral vascular diseases	0.000	0.610	0.390
I21 Acute myocardial infarction	0.000	0.619	0.381
I12.9 Hypertensive renal disease without renal failure	0.000	0.627	0.373
I13 Hypertensive heart and renal disease	0.000	0.629	0.371
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.630	0.370
I00-I02 Acute rheumatic fever	0.000	0.634	0.366
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.634	0.366
I73.9 Peripheral vascular disease, unspecified	0.000	0.645	0.355
I05-I09 Chronic rheumatic heart diseases	0.000	0.645	0.355
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.646	0.354
I21.4 Acute subendocardial myocardial infarction	0.000	0.646	0.354
I11 Hypertensive heart disease	0.000	0.646	0.354
I15 Secondary hypertension	0.000	0.646	0.353
I12.0 Hypertensive renal disease with renal failure	0.000	0.647	0.353
I23 Certain current complications following acute myocardial infarction	0.000	0.648	0.352
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.651	0.349
I77.8 Other specified disorders of arteries and arterioles	0.000	0.652	0.348
I20.0 Unstable angina	0.000	0.652	0.348
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.653	0.347
I74.8 Embolism and thrombosis of other arteries	0.000	0.653	0.347
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.653	0.347
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.653	0.347
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.653	0.347
I24 Other acute ischaemic heart diseases	0.000	0.655	0.345
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.659	0.341
I60-I69 Cerebrovascular diseases	0.000	0.663	0.337
I78 Diseases of capillaries	0.000	0.672	0.328
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.676	0.324
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.678	0.322
I77.6 Arteritis, unspecified	0.000	0.678	0.322
I74.5 Embolism and thrombosis of iliac artery	0.000	0.683	0.317
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.685	0.315
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.685	0.315
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.685	0.315
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.685	0.315
I71.0 Dissection of aorta [any part]	0.000	0.687	0.313
I77.1 Stricture of artery	0.000	0.692	0.308
I20.1 Angina pectoris with documented spasm	0.000	0.696	0.304
I60 Subarachnoid haemorrhage	0.000	0.704	0.296
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.707	0.293
I77.5 Necrosis of artery	0.000	0.708	0.292
I77.4 Coeliac artery compression syndrome	0.000	0.708	0.292
I77.3 Arterial fibromuscular dysplasia	0.000	0.708	0.292
I77.2 Rupture of artery	0.000	0.708	0.292
I07 Rheumatic tricuspid valve diseases	0.000	0.713	0.287
I77.0 Arteriovenous fistula, acquired	0.000	0.716	0.283
I69 Sequelae of cerebrovascular disease	0.000	0.718	0.282
I73.8 Other specified peripheral vascular diseases	0.000	0.720	0.280
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.720	0.280
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.725	0.275
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.727	0.273
I27 Other pulmonary heart diseases	0.000	0.727	0.273
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.729	0.270
I70 Atherosclerosis	0.000	0.730	0.270
I72 Other aneurysm	0.000	0.734	0.266
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.734	0.266
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.734	0.266
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.734	0.266
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.734	0.266
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.737	0.263
I20.8 Other forms of angina pectoris	0.000	0.737	0.263
I02 Rheumatic chorea	0.000	0.737	0.263
I01 Rheumatic fever with heart involvement	0.000	0.737	0.263
I00 Rheumatic fever without mention of heart involvement	0.000	0.737	0.263
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.738	0.262
I79.1 Aortitis in diseases classified elsewhere	0.000	0.738	0.262
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.738	0.262
I24.8 Other forms of acute ischaemic heart disease	0.000	0.738	0.262
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.739	0.261
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.743	0.257
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.743	0.257
I09 Other rheumatic heart diseases	0.000	0.745	0.254
I06 Rheumatic aortic valve diseases	0.000	0.745	0.254
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.746	0.254
I15.9 Seconday hypertension, unspecified	0.000	0.746	0.253
I15.8 Other secondary hypertension	0.000	0.746	0.253
I15.2 Hypertension secondary to endocrine disorders	0.000	0.746	0.253
I15.0 Renovascular hypertension	0.000	0.746	0.253
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.748	0.252
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.748	0.252
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.748	0.252
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.748	0.252
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.748	0.252
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.748	0.252
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.748	0.252
I05 Rheumatic mitral valve diseases	0.000	0.751	0.249
I69.3 Sequelae of cerebral infarction	0.000	0.751	0.249
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.752	0.248
I24.1 Dressler's syndrome	0.000	0.753	0.247
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.754	0.246
I28 Other diseases of pulmonary vessels	0.000	0.755	0.245
I99 Other and unspecified disorders of circulatory system	0.000	0.757	0.243
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.757	0.242
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.758	0.242
I07.1 Tricuspid insufficiency	0.000	0.762	0.238
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.763	0.236
I15.1 Hypertension secondary to other renal disorders	0.000	0.764	0.236
I78.9 Disease of capillaries, unspecified	0.000	0.765	0.235
I78.8 Other diseases of capillaries	0.000	0.765	0.235
I27.0 Primary pulmonary hypertension	0.000	0.769	0.231
I65.2 Occlusion and stenosis of carotid artery	0.000	0.770	0.230
I60.8 Other subarachnoid haemorrhage	0.000	0.770	0.229
I23.8 Other current complications following acute myocardial infarction	0.000	0.774	0.226
I22 Subsequent myocardial infarction	0.000	0.776	0.223
I27.2 Other secondary pulmonary hypertension	0.000	0.777	0.223
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.778	0.221
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.778	0.221
I67 Other cerebrovascular diseases	0.000	0.779	0.221
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.788	0.212
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.788	0.212
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.788	0.212
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.788	0.212
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.788	0.212
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.789	0.211
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.793	0.207
I07.9 Tricuspid valve disease, unspecified	0.000	0.794	0.206
I07.8 Other tricuspid valve diseases	0.000	0.794	0.206
I07.2 Tricuspid stenosis with insufficiency	0.000	0.794	0.206
I07.0 Tricuspid stenosis	0.000	0.794	0.206
I63 Cerebral infarction	0.000	0.798	0.202
I05.9 Mitral valve disease, unspecified	0.000	0.799	0.200
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.800	0.200
I08 Multiple valve diseases	0.000	0.801	0.199
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.803	0.197
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.803	0.197
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.803	0.197
I65.1 Occlusion and stenosis of basilar artery	0.000	0.803	0.197
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.803	0.197
I27.8 Other specified pulmonary heart diseases	0.000	0.804	0.196
I27.1 Kyphoscoliotic heart disease	0.000	0.804	0.196
I78.1 Naevus, nonneoplastic	0.000	0.805	0.195
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.806	0.194
I70.9 Generalised and unspecified atherosclerosis	0.000	0.806	0.194
I70.8 Atherosclerosis of other arteries	0.000	0.806	0.194
I70.1 Atherosclerosis of renal artery	0.000	0.806	0.194
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.808	0.192
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.809	0.191
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.809	0.191
I72.2 Aneurysm of renal artery	0.000	0.809	0.191
I72.1 Aneurysm of artery of upper extremity	0.000	0.809	0.191
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.811	0.188
I01.8 Other acute rheumatic heart disease	0.000	0.811	0.188
I01.2 Acute rheumatic myocarditis	0.000	0.811	0.188
I01.1 Acute rheumatic endocarditis	0.000	0.811	0.188
I01.0 Acute rheumatic pericarditis	0.000	0.811	0.188
I02.9 Rheumatic chorea without heart involvement	0.000	0.811	0.188
I02.0 Rheumatic chorea with heart involvement	0.000	0.811	0.188
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.812	0.188
I72.8 Aneurysm of other specified arteries	0.000	0.816	0.183
I72.3 Aneurysm of iliac artery	0.000	0.817	0.183
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.817	0.182
I06.8 Other rheumatic aortic valve diseases	0.000	0.817	0.182
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.817	0.182
I06.1 Rheumatic aortic insufficiency	0.000	0.817	0.182
I06.0 Rheumatic aortic stenosis	0.000	0.817	0.182
I09.9 Rheumatic heart disease, unspecified	0.000	0.817	0.182
I09.8 Other specified rheumatic heart diseases	0.000	0.817	0.182
I09.2 Chronic rheumatic pericarditis	0.000	0.817	0.182
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.817	0.182
I09.0 Rheumatic myocarditis	0.000	0.817	0.182
I05.8 Other mitral valve diseases	0.000	0.821	0.179
I05.1 Rheumatic mitral insufficiency	0.000	0.821	0.179
I72.4 Aneurysm of artery of lower extremity	0.000	0.823	0.177
I62 Other nontraumatic intracranial haemorrhage	0.000	0.823	0.176
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.824	0.176
I28.8 Other specified diseases of pulmonary vessels	0.000	0.824	0.176
I28.1 Aneurysm of pulmonary artery	0.000	0.824	0.176
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.824	0.176
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.826	0.173
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.826	0.173
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.826	0.173
I68.0 Cerebral amyloid angiopathy	0.000	0.826	0.173
I72.0 Aneurysm of carotid artery	0.000	0.827	0.173
I72.9 Aneurysm of unspecified site	0.000	0.827	0.173
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.827	0.172
I05.2 Mitral stenosis with insufficiency	0.000	0.827	0.172
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.828	0.172
I20.9 Angina pectoris, unspecified	0.000	0.829	0.171
I67.2 Cerebral atherosclerosis	0.000	0.830	0.170
I26 Pulmonary embolism	0.000	0.830	0.169
I70.0 Atherosclerosis of aorta	0.001	0.831	0.169
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.831	0.169
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.835	0.165
I67.1 Cerebral aneurysm, nonruptured	0.000	0.835	0.164
I22.8 Subsequent myocardial infarction of other sites	0.000	0.837	0.163
I08.0 Disorders of both mitral and aortic valves	0.000	0.838	0.162
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.842	0.158
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.842	0.158
I67.5 Moyamoya disease	0.000	0.842	0.158
I67.4 Hypertensive encephalopathy	0.000	0.842	0.158
I67.3 Progressive vascular leukoencephalopathy	0.000	0.842	0.158
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.842	0.158
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.845	0.155
I95 Hypotension	0.000	0.846	0.154
I67.8 Other specified cerebrovascular diseases	0.000	0.850	0.150
I63.8 Other cerebral infarction	0.000	0.851	0.149
I73.0 Raynaud's syndrome	0.000	0.852	0.148
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.852	0.148
I05.0 Mitral stenosis	0.000	0.852	0.148
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.852	0.147
I70.2 Atherosclerosis of arteries of the extremities	0.001	0.853	0.147
I63.9 Cerebral infarction, unspecified	0.000	0.855	0.145
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.855	0.145
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.855	0.145
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.855	0.145
I21.9 Acute myocardial infarction, unspecified	0.000	0.856	0.144
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.856	0.143
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.856	0.143
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.856	0.143
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.856	0.143
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.856	0.143
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.856	0.143
I08.9 Multiple valve disease, unspecified	0.000	0.857	0.142
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.858	0.142
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.860	0.139
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.860	0.139
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.860	0.139
I98.0 Cardiovascular syphilis	0.000	0.860	0.139
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.861	0.139
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.861	0.139
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.861	0.139
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.861	0.139
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.861	0.139
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.861	0.139
I21.2 Acute transmural myocardial infarction of other sites	0.001	0.863	0.137
I27.9 Pulmonary heart disease, unspecified	0.000	0.865	0.135
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.865	0.135
I95.1 Orthostatic hypotension	0.000	0.867	0.133
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.870	0.130
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.872	0.128
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.872	0.128
I62.1 Nontraumatic extradural haemorrhage	0.000	0.873	0.127
I61 Intracerebral haemorrhage	0.000	0.876	0.123
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.876	0.123
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.877	0.123
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.878	0.122
I70.01 Atherosclerosis of aorta (with gangrene)	0.001	0.878	0.121
I08.8 Other multiple valve diseases	0.000	0.879	0.121
I67.9 Cerebrovascular disease, unspecified	0.000	0.880	0.120
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.881	0.118
I97.0 Postcardiotomy syndrome	0.000	0.881	0.118
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.885	0.114
I95.0 Idiopathic hypotension	0.000	0.889	0.111
I97.1 Other functional disturbances following cardiac surgery	0.000	0.891	0.109
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.893	0.107
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.001	0.894	0.105
I95.2 Hypotension due to drugs	0.000	0.896	0.104
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.001	0.898	0.101
I95.8 Other hypotension	0.000	0.900	0.100
I22.1 Subsequent myocardial infarction of inferior wall	0.001	0.902	0.097
I70.00 Atherosclerosis of aorta (without gangrene)	0.001	0.903	0.096
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.905	0.095
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.001	0.906	0.093
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.908	0.092
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.911	0.089
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.911	0.089
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.911	0.089
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.911	0.089
I30-I52 Other forms of heart disease	0.000	0.911	0.089
I50 Heart failure	0.000	0.912	0.088
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.915	0.084
I50.1 Left ventricular failure	0.000	0.919	0.081
I50.9 Heart failure, unspecified	0.000	0.922	0.078
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.922	0.077
I50.0 Congestive heart failure	0.000	0.925	0.075
I46 Cardiac arrest	0.000	0.930	0.070
I35 Nonrheumatic aortic valve disorders	0.000	0.932	0.067
I37 Pulmonary valve disorders	0.000	0.933	0.067
I35.0 Aortic (valve) stenosis	0.000	0.934	0.066
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.936	0.064
I52 Other heart disorders in diseases classified elsewhere	0.000	0.936	0.064
I48 Atrial fibrillation and flutter	0.000	0.936	0.064
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.936	0.064
I41 Myocarditis in diseases classified elsewhere	0.000	0.936	0.064
I40 Acute myocarditis	0.000	0.936	0.064
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.936	0.064
I32 Pericarditis in diseases classified elsewhere	0.000	0.936	0.064
I61.8 Other intracerebral haemorrhage	0.001	0.936	0.063
I33 Acute and subacute endocarditis	0.000	0.939	0.061
I46.0 Cardiac arrest with successful resuscitation	0.000	0.939	0.061
I36 Nonrheumatic tricuspid valve disorders	0.000	0.939	0.061
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.001	0.941	0.058
I47 Paroxysmal tachycardia	0.000	0.942	0.058
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.943	0.057
I49 Other cardiac arrhythmias	0.000	0.944	0.056
I51 Complications and ill-defined descriptions of heart disease	0.000	0.944	0.056
I35.8 Other aortic valve disorders	0.000	0.946	0.054
I37.1 Pulmonary valve insufficiency	0.000	0.948	0.051
I46.1 Sudden cardiac death, so described	0.000	0.950	0.050
I38 Endocarditis, valve unspecified	0.000	0.950	0.050
I37.9 Pulmonary valve disorder, unspecified	0.000	0.952	0.048
I37.8 Other pulmonary valve disorders	0.000	0.952	0.048
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.952	0.048
I37.0 Pulmonary valve stenosis	0.000	0.952	0.048
I51.7 Cardiomegaly	0.000	0.952	0.048
I33.0 Acute and subacute infective endocarditis	0.000	0.953	0.047
I42 Cardiomyopathy	0.000	0.953	0.047
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.954	0.046
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.954	0.046
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.954	0.046
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.954	0.046
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.954	0.046
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.954	0.046
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.954	0.046
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.954	0.046
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.954	0.046
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.954	0.046
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.954	0.046
I40.9 Acute myocarditis, unspecified	0.000	0.954	0.046
I40.8 Other acute myocarditis	0.000	0.954	0.046
I40.1 Isolated myocarditis	0.000	0.954	0.046
I40.0 Infective myocarditis	0.000	0.954	0.046
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.954	0.046
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.954	0.046
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.954	0.046
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.954	0.046
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.954	0.046
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.954	0.046
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.954	0.046
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.954	0.046
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.954	0.046
I48.4 Atypical atrial flutter	0.000	0.954	0.046
I48.3 Typical atrial flutter	0.000	0.954	0.046
I48.2 Chronic atrial fibrillation	0.000	0.954	0.046
I48.1 Persistent atrial fibrillation	0.000	0.954	0.046
I48.0 Paroxysmal atrial fibrillation	0.000	0.954	0.046
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.954	0.046
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.954	0.046
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.954	0.046
I49.8 Other specified cardiac arrhythmias	0.000	0.954	0.046
I45 Other conduction disorders	0.000	0.954	0.045
I49.5 Sick sinus syndrome	0.000	0.955	0.045
I49.0 Ventricular fibrillation and flutter	0.000	0.955	0.045
I47.2 Ventricular tachycardia	0.000	0.955	0.045
I30 Acute pericarditis	0.000	0.955	0.044
I49.1 Atrial premature depolarisation	0.000	0.955	0.045
G43.9 Migraine, unspecified	0.000	0.955	0.045
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.956	0.044
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.956	0.044
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.956	0.044
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.956	0.044
I51.0 Cardiac septal defect, acquired	0.000	0.957	0.043
I35.9 Aortic valve disorder, unspecified	0.000	0.958	0.042
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.959	0.041
I31 Other diseases of pericardium	0.000	0.959	0.041
I46.9 Cardiac arrest, unspecified	0.000	0.959	0.041
I51.8 Other ill-defined heart diseases	0.000	0.959	0.041
I34 Nonrheumatic mitral valve disorders	0.000	0.959	0.041
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.959	0.041
I49.2 Junctional premature depolarisation	0.000	0.960	0.040
I51.5 Myocardial degeneration	0.000	0.960	0.040
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.960	0.040
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.960	0.040
I47.0 Reentry ventricular arrhythmia	0.000	0.961	0.039
I51.9 Heart disease, unspecified	0.000	0.962	0.038
I82 Other venous embolism and thrombosis	0.000	0.962	0.038
I45.5 Other specified heart block	0.000	0.963	0.037
I86 Varicose veins of other sites	0.000	0.963	0.037
I42.9 Cardiomyopathy, unspecified	0.000	0.963	0.037
I33.9 Acute endocarditis, unspecified	0.000	0.963	0.036
I51.6 Cardiovascular disease, unspecified	0.000	0.963	0.036
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.965	0.035
I49.3 Ventricular premature depolarisation	0.000	0.965	0.035
I47.1 Supraventricular tachycardia	0.000	0.965	0.035
I45.1 Other and unspecified right bundle-branch block	0.000	0.966	0.034
I45.8 Other specified conduction disorders	0.000	0.966	0.034
I42.8 Other cardiomyopathies	0.000	0.966	0.034
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.966	0.034
I42.5 Other restrictive cardiomyopathy	0.000	0.966	0.034
I42.4 Endocardial fibroelastosis	0.000	0.966	0.034
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.966	0.034
I88 Nonspecific lymphadenitis	0.000	0.967	0.033
I85 Oesophageal varices	0.000	0.967	0.033
I45.3 Trifascicular block	0.000	0.967	0.033
I45.0 Right fascicular block	0.000	0.967	0.033
I42.6 Alcoholic cardiomyopathy	0.000	0.967	0.032
I30.8 Other forms of acute pericarditis	0.000	0.968	0.032
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.968	0.032
I82.8 Embolism and thrombosis of other specified veins	0.000	0.968	0.032
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.968	0.032
I45.4 Nonspecific intraventricular block	0.000	0.968	0.032
I81 Portal vein thrombosis	0.000	0.968	0.032
I42.2 Other hypertrophic cardiomyopathy	0.000	0.968	0.032
E70-E90 Metabolic disorders	0.000	0.969	0.031
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.969	0.031
I86.1 Scrotal varices	0.000	0.969	0.031
G43 Migraine	0.000	0.970	0.030
I31.8 Other specified diseases of pericardium	0.000	0.970	0.030
I31.2 Haemopericardium, not elsewhere classified	0.000	0.970	0.030
I31.1 Chronic constrictive pericarditis	0.000	0.970	0.030
I31.0 Chronic adhesive pericarditis	0.000	0.970	0.030
I30.1 Infective pericarditis	0.000	0.970	0.029
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.970	0.030
I86.4 Gastric varices	0.000	0.971	0.029
G43.1 Migraine with aura [classical migraine]	0.000	0.972	0.028
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.972	0.027
I34.1 Mitral (valve) prolapse	0.000	0.973	0.027
I82.3 Embolism and thrombosis of renal vein	0.000	0.973	0.027
I82.1 Thrombophlebitis migrans	0.000	0.973	0.027
I82.0 Budd-Chiari syndrome	0.000	0.973	0.027
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.973	0.027
I45.2 Bifascicular block	0.000	0.973	0.027
I86.3 Vulval varices	0.000	0.973	0.027
I86.2 Pelvic varices	0.000	0.973	0.027
I86.0 Sublingual varices	0.000	0.973	0.027
I82.2 Embolism and thrombosis of vena cava	0.000	0.973	0.026
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.974	0.026
I31.3 Pericardial effusion (noninflammatory)	0.000	0.975	0.025
I85.0 Oesophageal varices with bleeding	0.000	0.975	0.025
I49.4 Other and unspecified premature depolarisation	0.000	0.975	0.024
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.976	0.024
I88.8 Other nonspecific lymphadenitis	0.000	0.976	0.024
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.976	0.024
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.976	0.024
I45.6 Preexcitation syndrome	0.000	0.976	0.024
I89.0 Lymphoedema, not elsewhere classified	0.000	0.976	0.024
E88 Other metabolic disorders	0.000	0.976	0.023
I51.4 Myocarditis, unspecified	0.001	0.977	0.023
I45.9 Conduction disorder, unspecified	0.000	0.977	0.023
E84 Cystic fibrosis	0.000	0.977	0.023
E79 Disorders of purine and pyrimidine metabolism	0.000	0.977	0.023
E77 Disorders of glycoprotein metabolism	0.000	0.977	0.023
E76 Disorders of glycosaminoglycan metabolism	0.000	0.977	0.023
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.977	0.023
E72 Other disorders of amino-acid metabolism	0.000	0.977	0.023
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.977	0.023
E70 Disorders of aromatic amino-acid metabolism	0.000	0.977	0.023
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.977	0.023
I34.0 Mitral (valve) insufficiency	0.000	0.977	0.023
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.977	0.023
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.978	0.022
I86.8 Varicose veins of other specified sites	0.000	0.978	0.022
E74 Other disorders of carbohydrate metabolism	0.000	0.978	0.022
I85.9 Oesophageal varices without bleeding	0.000	0.978	0.022
G43.3 Complicated migraine	0.000	0.978	0.022
G43.2 Status migrainosus	0.000	0.978	0.022
G43.0 Migraine without aura [common migraine]	0.000	0.978	0.022
E73 Lactose intolerance	0.000	0.979	0.021
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.979	0.021
I35.2 Aortic (valve) stenosis with insufficiency	0.001	0.979	0.020
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.979	0.020
I89.1 Lymphangitis	0.000	0.980	0.020
I42.0 Dilated cardiomyopathy	0.000	0.980	0.020
E86 Volume depletion	0.000	0.980	0.020
G43.8 Other migraine	0.000	0.981	0.019
I83 Varicose veins of lower extremities	0.000	0.981	0.019
O80.0 Spontaneous vertex delivery	0.000	0.981	0.019
I30.9 Acute pericarditis, unspecified	0.001	0.981	0.018
E85 Amyloidosis	0.000	0.982	0.018
E89.2 Postprocedural hypoparathyroidism	0.000	0.982	0.018
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.982	0.018
I80 Phlebitis and thrombophlebitis	0.000	0.982	0.018
E88.9 Metabolic disorder, unspecified	0.000	0.983	0.017
E88.8 Other specified metabolic disorders	0.000	0.983	0.017
E88.3 Tumour lysis syndrome	0.000	0.983	0.017
E88.2 Lipomatosis, not elsewhere classified	0.000	0.983	0.017
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.983	0.017
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.983	0.016
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.983	0.016
E70.3 Albinism	0.000	0.983	0.016
E70.2 Disorders of tyrosine metabolism	0.000	0.983	0.016
E70.1 Other hyperphenylalaninaemias	0.000	0.983	0.016
E70.0 Classical phenylketonuria	0.000	0.983	0.016
E71.3 Disorders of fatty-acid metabolism	0.000	0.983	0.016
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.983	0.016
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.983	0.016
E71.0 Maple-syrup-urine disease	0.000	0.983	0.016
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.983	0.016
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.983	0.016

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations