TreeWAS – Variant ID: rs17672135

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M54.46 Lumbago with sciatica (Lumbar region)	0.017	0.983	0.000
Z74.0 Reduced mobility	0.017	0.983	0.000
M54.4 Lumbago with sciatica	0.012	0.988	0.000
R22.2 Localised swelling, mass and lump, trunk	0.011	0.989	0.000
I51.9 Heart disease, unspecified	0.011	0.989	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.011	0.989	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.011	0.989	0.000
Z90.5 Acquired absence of kidney	0.000	0.990	0.010
D25.2 Subserosal leiomyoma of uterus	0.000	0.990	0.010
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.009	0.991	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.009	0.991	0.000
M54.44 Lumbago with sciatica-Thoracic	0.009	0.991	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.009	0.991	0.000
M54.42 Lumbago with sciatica-Cervical	0.009	0.991	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.009	0.991	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.009	0.991	0.000
I51 Complications and ill-defined descriptions of heart disease	0.009	0.991	0.000
D69.6 Thrombocytopenia, unspecified	0.009	0.991	0.000
I51.7 Cardiomegaly	0.008	0.992	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.007	0.993	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.007	0.993	0.000
I51.4 Myocarditis, unspecified	0.007	0.993	0.000
I51.8 Other ill-defined heart diseases	0.007	0.993	0.000
D25.9 Leiomyoma of uterus, unspecified	0.000	0.993	0.007
R04.2 Haemoptysis	0.000	0.993	0.007
N41.1 Chronic prostatitis	0.007	0.993	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.007	0.993	0.000
I51.0 Cardiac septal defect, acquired	0.007	0.993	0.000
N41.0 Acute prostatitis	0.007	0.993	0.000
I51.5 Myocardial degeneration	0.006	0.993	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.006	0.993	0.000
D25 Leiomyoma of uterus	0.000	0.993	0.007
D69 Purpura and other haemorrhagic conditions	0.006	0.994	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.006	0.994	0.000
R22.0 Localised swelling, mass and lump, head	0.006	0.994	0.000
Z74 Problems related to care-provider dependency	0.006	0.994	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.006	0.994	0.000
I51.6 Cardiovascular disease, unspecified	0.006	0.994	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.994	0.006
D69.5 Secondary thrombocytopenia	0.006	0.994	0.000
N41 Inflammatory diseases of prostate	0.006	0.994	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.005	0.995	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.995	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.005	0.995	0.000
D69.0 Allergic purpura	0.005	0.995	0.000
Q38.7 Pharyngeal pouch	0.005	0.995	0.000
W55.0 Home	0.005	0.995	0.000
R22.1 Localised swelling, mass and lump, neck	0.005	0.995	0.000
D69.8 Other specified haemorrhagic conditions	0.005	0.995	0.000
D69.2 Other nonthrombocytopenic purpura	0.005	0.995	0.000
D69.1 Qualitative platelet defects	0.005	0.995	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.005	0.995	0.000
Z74.1 Need for assistance with personal care	0.005	0.995	0.000
Z74.3 Need for continuous supervision	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
Q23.1 Congenital insufficiency of aortic valve	0.005	0.995	0.000
D69.9 Haemorrhagic condition, unspecified	0.004	0.995	0.000
D69.4 Other primary thrombocytopenia	0.004	0.995	0.000
Z74.8 Other problems related to care-provider dependency	0.004	0.995	0.000
Q23 Congenital malformations of aortic and mitral valves	0.004	0.995	0.000
M79.10 Myalgia (Multiple sites)	0.004	0.996	0.000
Q24.8 Other specified congenital malformations of heart	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
D25.1 Intramural leiomyoma of uterus	0.000	0.996	0.004
R22.9 Localised swelling, mass and lump, unspecified	0.004	0.996	0.000
N41.8 Other inflammatory diseases of prostate	0.004	0.996	0.000
N41.3 Prostatocystitis	0.004	0.996	0.000
N41.2 Abscess of prostate	0.004	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
D25.0 Submucous leiomyoma of uterus	0.000	0.996	0.004
Z74.2 Need for assistance at home and no other household member able to render care	0.004	0.996	0.000
W55 Bitten or struck by other mammals	0.004	0.996	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.996	0.004
Q24.9 Congenital malformation of the heart, unspecified	0.004	0.996	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.996	0.004
Y41 Other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
Q23.0 Congenital stenosis of aortic valve	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.003	0.996	0.000
Q24.2 Cor triatriatum	0.003	0.996	0.000
Q24.1 Levocardia	0.003	0.996	0.000
Q24.0 Dextrocardia	0.003	0.996	0.000
Q25 Congenital malformations of great arteries	0.004	0.996	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.004	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.996	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.996	0.000
Q23.2 Congenital mitral stenosis	0.003	0.996	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.997	0.003
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
W55.8 Other specified place	0.003	0.997	0.000
Y43.4 Immunosuppressive agents	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.003	0.997	0.000
Q38.6 Other congenital malformations of mouth	0.003	0.997	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.003	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.003	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.003	0.997	0.000
Q38.2 Macroglossia	0.003	0.997	0.000
Q38.1 Ankyloglossia	0.003	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
I42 Cardiomyopathy	0.000	0.997	0.003
R04 Haemorrhage from respiratory passages	0.000	0.997	0.003
H27.0 Aphakia	0.003	0.997	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.997	0.003
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.003	0.997	0.000
W55.9 Unspecified place	0.003	0.997	0.000
W55.5 Trade and service area	0.003	0.997	0.000
W55.7 Farm	0.003	0.997	0.000
W55.6 Industrial and construction area	0.003	0.997	0.000
W55.4 Street and highway	0.003	0.997	0.000
W55.3 Sports and athletics area	0.003	0.997	0.000
W55.2 School, other institution and public administrative area	0.003	0.997	0.000
W55.1 Residential institution	0.003	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
I42.0 Dilated cardiomyopathy	0.000	0.997	0.003
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
Y41.5 Antiviral drugs	0.003	0.997	0.000
Y41.4 Anthelminthics	0.003	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.003	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
Y41.1 Antimycobacterial drugs	0.003	0.997	0.000
Y41.0 Sulphonamides	0.003	0.997	0.000
Z90.8 Acquired absence of other organs	0.000	0.997	0.003
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.997	0.003
Y43 Primarily systemic agents	0.003	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
I34.0 Mitral (valve) insufficiency	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.997	0.000
Q25.4 Other congenital malformations of aorta	0.003	0.997	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
Q25.2 Atresia of aorta	0.003	0.997	0.000
Q25.0 Patent ductus arteriosus	0.003	0.997	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.000	0.997	0.003
W50-W64 Exposure to animate mechanical forces	0.003	0.997	0.000
D48.6 Breast	0.003	0.997	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.997	0.003
R04.0 Epistaxis	0.000	0.997	0.003
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Y43.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.003	0.997	0.000
Y43.1 Antineoplastic antimetabolites	0.003	0.997	0.000
I12 Hypertensive renal disease	0.000	0.997	0.003
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.997	0.003
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
S90.8 Other superficial injuries of ankle and foot	0.003	0.997	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.003	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.997	0.000
Q20.4 Double inlet ventricle	0.002	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.997	0.000
Q20.2 Double outlet left ventricle	0.002	0.997	0.000
Q20.1 Double outlet right ventricle	0.002	0.997	0.000
Q20.0 Common arterial trunk	0.002	0.997	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.002	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.002	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.002	0.997	0.000
Q22.5 Ebstein's anomaly	0.002	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.002	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.002	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.002	0.997	0.000
Q22.1 Congenital pulmonary valve stenosis	0.002	0.997	0.000
Q22.0 Pulmonary valve atresia	0.002	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.1 Persistent left superior vena cava	0.002	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.997	0.003
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.002	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
H49.2 Sixth [abducent] nerve palsy	0.003	0.997	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.997	0.002
I42.5 Other restrictive cardiomyopathy	0.000	0.997	0.002
I42.4 Endocardial fibroelastosis	0.000	0.997	0.002
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.997	0.002
D48.7 Other specified sites	0.003	0.997	0.000
R04.9 Haemorrhage from respiratory passages, unspecified	0.000	0.997	0.002
R04.1 Haemorrhage from throat	0.000	0.997	0.002
Z90.0 Acquired absence of part of head and neck	0.000	0.997	0.003
W60 Contact with plant thorns and spines and sharp leaves	0.002	0.997	0.000
D48.1 Connective and other soft tissue	0.003	0.997	0.000
N73.6 Female pelvic peritoneal adhesions	0.000	0.997	0.003
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.997	0.000
I42.8 Other cardiomyopathies	0.000	0.997	0.002
I42.6 Alcoholic cardiomyopathy	0.000	0.997	0.002
Q82.8 Other specified congenital malformations of skin	0.002	0.997	0.000
Q15.0 Congenital glaucoma	0.002	0.997	0.000
Z90.4 Acquired absence of other parts of digestive tract	0.000	0.997	0.003
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.997	0.000
W55.58 Bitten or struck by other mammals; Trade and service area;While engaged in other specified activities	0.002	0.997	0.000
W55.99 Bitten or struck by other mammals: Unspecified place: During unspecified activity	0.002	0.997	0.000
N99.1 Postprocedural urethral stricture	0.000	0.997	0.002
Y49.5 Other antipsychotics and neuroleptics	0.002	0.997	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.000	0.997	0.002
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.003	0.997	0.000
Q83 Congenital malformations of breast	0.002	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.997	0.000
Q12 Congenital lens malformations	0.002	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Q82.2 Mastocytosis	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.998	0.002
W60.0 Home	0.002	0.998	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.002	0.998	0.000
D66 Hereditary factor VIII deficiency	0.002	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
Q17.5 Prominent ear	0.002	0.998	0.000
Q43.8 Other specified congenital malformations of intestine	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.998	0.002
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
Q35 Cleft palate	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.998	0.000
W64 Exposure to other and unspecified animate mechanical forces	0.002	0.998	0.000
W59 Bitten or crushed by other reptiles	0.002	0.998	0.000
W58 Bitten or struck by crocodile or alligator	0.002	0.998	0.000
W56 Contact with marine animal	0.002	0.998	0.000
W54 Bitten or struck by dog	0.002	0.998	0.000
W53 Bitten by rat	0.002	0.998	0.000
W52 Crushed, pushed and stepped on by crowd or human stampede	0.002	0.998	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.002	0.998	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.002	0.998	0.000
Q18.8 Other specified congenital malformations of face and neck	0.002	0.998	0.000
Q18.7 Microcheilia	0.002	0.998	0.000
Q18.6 Macrocheilia	0.002	0.998	0.000
Q18.5 Microstomia	0.002	0.998	0.000
Q18.4 Macrostomia	0.002	0.998	0.000
Q18.3 Webbing of neck	0.002	0.998	0.000
Q18.2 Other branchial cleft malformations	0.002	0.998	0.000
Q18.1 Preauricular sinus and cyst	0.002	0.998	0.000
R04.8 Haemorrhage from other sites in respiratory passages	0.000	0.998	0.002
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Q10.0 Congenital ptosis	0.002	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.002	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.002	0.998	0.000
Q82.3 Incontinentia pigmenti	0.002	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.002	0.998	0.000
Q82.0 Hereditary lymphoedema	0.002	0.998	0.000
Q90 Down's syndrome	0.002	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
Q15.9 Congenital malformation of eye, unspecified	0.002	0.998	0.000
Q15.8 Other specified congenital malformations of eye	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.002	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
Q40.1 Congenital hiatus hernia	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.002	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.002	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.002	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.002	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.002	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.002	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.002	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.002	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.002	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.002	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.002	0.998	0.000
Q44.7 Other congenital malformations of liver	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
Q44.4 Choledochal cyst	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.998	0.000
Q45.1 Annular pancreas	0.002	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.998	0.000
Q61 Cystic kidney disease	0.000	0.998	0.002
I12.9 Hypertensive renal disease without renal failure	0.000	0.998	0.002
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
W51 Striking against or bumped into by another person	0.002	0.998	0.000
Q17.9 Congenital malformation of ear, unspecified	0.002	0.998	0.000
Q17.8 Other specified congenital malformations of ear	0.002	0.998	0.000
Q17.4 Misplaced ear	0.002	0.998	0.000
Q17.3 Other misshapen ear	0.002	0.998	0.000
Q17.2 Microtia	0.002	0.998	0.000
Q17.1 Macrotia	0.002	0.998	0.000
Q17.0 Accessory auricle	0.002	0.998	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.002	0.998	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
K60.1 Chronic anal fissure	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.998	0.002
Q10.7 Congenital malformation of orbit	0.002	0.998	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.002	0.998	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.002	0.998	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.002	0.998	0.000
Q10.3 Other congenital malformations of eyelid	0.002	0.998	0.000
Q10.2 Congenital entropion	0.002	0.998	0.000
Q10.1 Congenital ectropion	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
Q43.7 Persistent cloaca	0.002	0.998	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.998	0.000
Q43.5 Ectopic anus	0.002	0.998	0.000
Q43.4 Duplication of intestine	0.002	0.998	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.998	0.000
Q43.1 Hirschsprung's disease	0.002	0.998	0.000
Q85.1 Tuberous sclerosis	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.002	0.998	0.000
D67 Hereditary factor IX deficiency	0.002	0.998	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.002	0.998	0.000
N99.2 Postprocedural adhesions of vagina	0.000	0.998	0.002
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
W50.0 Home	0.002	0.998	0.000
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.002
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
Q35.9 Cleft palate, unspecified	0.002	0.998	0.000
Q83.8 Other congenital malformations of breast	0.002	0.998	0.000
W23.4 Street and highway	0.002	0.998	0.000
W60.9 Unspecified place	0.002	0.998	0.000
W60.8 Other specified place	0.002	0.998	0.000
W60.7 Farm	0.002	0.998	0.000
W60.6 Industrial and construction area	0.002	0.998	0.000
W60.5 Trade and service area	0.002	0.998	0.000
W60.4 Street and highway	0.002	0.998	0.000
W60.3 Sports and athletics area	0.002	0.998	0.000
W60.2 School, other institution and public administrative area	0.002	0.998	0.000
W60.1 Residential institution	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
D48.0 Bone and articular cartilage	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q04 Other congenital malformations of brain	0.002	0.998	0.000
Q03 Congenital hydrocephalus	0.002	0.998	0.000
Q01 Encephalocele	0.002	0.998	0.000
Q00 Anencephaly and similar malformations	0.002	0.998	0.000
Q02 Microcephaly	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.998	0.002
Q83.1 Accessory breast	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.002	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.002
Q11.3 Macrophthalmos	0.002	0.998	0.000
Q11.2 Microphthalmos	0.002	0.998	0.000
Q11.1 Other anophthalmos	0.002	0.998	0.000
Q11.0 Cystic eyeball	0.002	0.998	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.002	0.998	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q13.5 Blue sclera	0.002	0.998	0.000
Q13.4 Other congenital corneal malformations	0.002	0.998	0.000
Q13.3 Congenital corneal opacity	0.002	0.998	0.000
Q13.2 Other congenital malformations of iris	0.002	0.998	0.000
Q13.1 Absence of iris	0.002	0.998	0.000
Q13.0 Coloboma of iris	0.002	0.998	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.002	0.998	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q14.3 Congenital malformation of choroid	0.002	0.998	0.000
Q14.2 Congenital malformation of optic disk	0.002	0.998	0.000
Q14.1 Congenital malformation of retina	0.002	0.998	0.000
Q14.0 Congenital malformation of vitreous humour	0.002	0.998	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.002	0.998	0.000
Q16.5 Congenital malformation of inner ear	0.002	0.998	0.000
Q16.4 Other congenital malformations of middle ear	0.002	0.998	0.000
Q16.3 Congenital malformation of ear ossicles	0.002	0.998	0.000
Q16.2 Absence of eustachian tube	0.002	0.998	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.002	0.998	0.000
Q16.0 Congenital absence of (ear) auricle	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.001	0.998	0.001
D48.4 Peritoneum	0.002	0.998	0.000
D48.3 Retroperitoneum	0.002	0.998	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
Q83.9 Congenital malformation of breast, unspecified	0.002	0.998	0.000
Q83.3 Accessory nipple	0.002	0.998	0.000
Q83.2 Absent nipple	0.002	0.998	0.000
Q83.0 Congenital absence of breast with absent nipple	0.002	0.998	0.000
W84.9 Unspecified place	0.002	0.998	0.000
Y76.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
Q12.9 Congenital lens malformation, unspecified	0.002	0.998	0.000
Q12.8 Other congenital lens malformations	0.002	0.998	0.000
Q12.4 Spherophakia	0.002	0.998	0.000
Q12.3 Congenital aphakia	0.002	0.998	0.000
Q12.2 Coloboma of lens	0.002	0.998	0.000
Q12.1 Congenital displaced lens	0.002	0.998	0.000
Q90.9 Down's syndrome, unspecified	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.998	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations