TreeWAS – Variant ID: rs17696736

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	1.000	0.000	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
Z95.5 Presence of coronary angioplasty implant and graft	1.000	0.000	0.000
I10 Essential (primary) hypertension	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I21 Acute myocardial infarction	1.000	0.000	0.000
Z95 Presence of cardiac and vascular implants and grafts	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
Z95.2 Presence of prosthetic heart valve	1.000	0.000	0.000
I10-I15 Hypertensive diseases	1.000	0.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000	0.000
Z95.1 Presence of aortocoronary bypass graft	1.000	0.000	0.000
Z95.4 Presence of other heart-valve replacement	0.999	0.001	0.000
I25.2 Old myocardial infarction	0.999	0.001	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.002	0.998
I20 Angina pectoris	0.995	0.005	0.000
I20.9 Angina pectoris, unspecified	0.995	0.005	0.000
E03 Other hypothyroidism	0.995	0.005	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.994	0.006	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.990	0.010	0.000
E00-E07 Disorders of thyroid gland	0.989	0.011	0.000
E10 Insulin-dependent diabetes mellitus	0.986	0.014	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.014	0.986
Z95.8 Presence of other cardiac and vascular implants and grafts	0.978	0.022	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.977	0.023	0.000
E10-E14 Diabetes mellitus	0.976	0.024	0.000
I22 Subsequent myocardial infarction	0.973	0.027	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.028	0.972
I73 Other peripheral vascular diseases	0.972	0.028	0.000
I73.9 Peripheral vascular disease, unspecified	0.969	0.031	0.000
I74 Arterial embolism and thrombosis	0.966	0.034	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.044	0.956
E05 Thyrotoxicosis [hyperthyroidism]	0.941	0.059	0.000
C78.7 Secondary malignant neoplasm of liver	0.000	0.066	0.934
I25.5 Ischaemic cardiomyopathy	0.934	0.066	0.000
I74.5 Embolism and thrombosis of iliac artery	0.934	0.066	0.000
E10.5 With peripheral circulatory complications	0.927	0.073	0.000
E10.4 With neurological complications	0.926	0.074	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.923	0.077	0.000
E05.9 Thyrotoxicosis, unspecified	0.918	0.082	0.000
I21.4 Acute subendocardial myocardial infarction	0.914	0.086	0.000
E10.9 Without complications	0.907	0.093	0.000
E10.3 With ophthalmic complications	0.902	0.098	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.102	0.898
E10.1 With ketoacidosis	0.897	0.103	0.000
E20-E35 Disorders of other endocrine glands	0.895	0.105	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.107	0.893
E10.2 With renal complications	0.891	0.109	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.111	0.889
C77.2 Intra-abdominal lymph nodes	0.000	0.114	0.886
I05-I09 Chronic rheumatic heart diseases	0.886	0.114	0.000
I23 Certain current complications following acute myocardial infarction	0.886	0.114	0.000
E06 Thyroiditis	0.872	0.128	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.872	0.128	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.135	0.865
I22.8 Subsequent myocardial infarction of other sites	0.862	0.138	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.146	0.854
C77.9 Lymph node, unspecified	0.000	0.150	0.850
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.151	0.849
E23 Hypofunction and other disorders of pituitary gland	0.848	0.152	0.000
E10.0 With coma	0.846	0.154	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.841	0.159	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.162	0.838
I05 Rheumatic mitral valve diseases	0.837	0.163	0.000
E03.8 Other specified hypothyroidism	0.827	0.173	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.824	0.176	0.000
I99 Other and unspecified disorders of circulatory system	0.821	0.179	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.819	0.181	0.000
Z95.3 Presence of xenogenic heart valve	0.819	0.181	0.000
I77 Other disorders of arteries and arterioles	0.811	0.189	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.810	0.190	0.000
E10.8 With unspecified complications	0.807	0.193	0.000
I23.8 Other current complications following acute myocardial infarction	0.804	0.196	0.000
I13 Hypertensive heart and renal disease	0.795	0.205	0.000
I25.4 Coronary artery aneurysm	0.795	0.205	0.000
I12 Hypertensive renal disease	0.792	0.208	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.210	0.790
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.212	0.788
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.787	0.213	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.785	0.215	0.000
E27 Other disorders of adrenal gland	0.776	0.224	0.000
I05.0 Mitral stenosis	0.768	0.232	0.000
E20 Hypoparathyroidism	0.767	0.233	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.767	0.233	0.000
E03.1 Congenital hypothyroidism without goitre	0.752	0.248	0.000
E23.6 Other disorders of pituitary gland	0.752	0.248	0.000
E23.2 Diabetes insipidus	0.748	0.252	0.000
I25.6 Silent myocardial ischaemia	0.746	0.254	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.745	0.255	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.744	0.256	0.000
E16 Other disorders of pancreatic internal secretion	0.744	0.256	0.000
E23.0 Hypopituitarism	0.744	0.256	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.263	0.737
I05.2 Mitral stenosis with insufficiency	0.735	0.265	0.000
E06.9 Thyroiditis, unspecified	0.732	0.268	0.000
I77.6 Arteritis, unspecified	0.727	0.273	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.720	0.280	0.000
E22 Hyperfunction of pituitary gland	0.718	0.282	0.000
E27.1 Primary adrenocortical insufficiency	0.718	0.282	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283	0.000
E03.5 Myxoedema coma	0.713	0.287	0.000
E03.4 Atrophy of thyroid (acquired)	0.713	0.287	0.000
E03.3 Postinfectious hypothyroidism	0.713	0.287	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.713	0.287	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.709	0.290	0.000
E00 Congenital iodine-deficiency syndrome	0.709	0.290	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.709	0.291	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.704	0.296	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.297	0.703
E12 Malnutrition-related diabetes mellitus	0.700	0.300	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.300	0.700
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.307	0.693
E16.2 Hypoglycaemia, unspecified	0.693	0.307	0.000
I07 Rheumatic tricuspid valve diseases	0.691	0.309	0.000
E06.3 Autoimmune thyroiditis	0.682	0.318	0.000
I15 Secondary hypertension	0.681	0.318	0.000
I73.8 Other specified peripheral vascular diseases	0.680	0.320	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.677	0.323	0.000
E05.5 Thyroid crisis or storm	0.675	0.325	0.000
E05.4 Thyrotoxicosis factitia	0.675	0.325	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.675	0.325	0.000
E06.1 Subacute thyroiditis	0.674	0.326	0.000
I25.3 Aneurysm of heart	0.674	0.326	0.000
I21.9 Acute myocardial infarction, unspecified	0.672	0.328	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.668	0.332	0.000
I77.1 Stricture of artery	0.667	0.333	0.000
E10.6 With other specified complications	0.666	0.334	0.000
I12.0 Hypertensive renal disease with renal failure	0.663	0.337	0.000
I20.8 Other forms of angina pectoris	0.662	0.338	0.000
E27.2 Addisonian crisis	0.662	0.338	0.000
I05.1 Rheumatic mitral insufficiency	0.661	0.339	0.000
I70 Atherosclerosis	0.661	0.339	0.000
E31 Polyglandular dysfunction	0.660	0.339	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.660	0.340	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.657	0.343	0.000
E25 Adrenogenital disorders	0.654	0.346	0.000
E10.7 With multiple complications	0.653	0.346	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.653	0.347	0.000
C80 Malignant neoplasm without specification of site	0.000	0.349	0.651
E28 Ovarian dysfunction	0.649	0.351	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.648	0.352	0.000
C76.0 Head, face and neck	0.000	0.352	0.648
E20.9 Hypoparathyroidism, unspecified	0.645	0.355	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.642	0.358	0.000
E32 Diseases of thymus	0.642	0.358	0.000
E30 Disorders of puberty, not elsewhere classified	0.642	0.358	0.000
I06 Rheumatic aortic valve diseases	0.635	0.365	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.635	0.365	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.635	0.365	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.635	0.365	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.635	0.365	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.635	0.365	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.635	0.365	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.635	0.365	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.635	0.365	0.000
E06.5 Other chronic thyroiditis	0.635	0.365	0.000
I00-I02 Acute rheumatic fever	0.635	0.365	0.000
E22.1 Hyperprolactinaemia	0.633	0.367	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.629	0.371	0.000
E06.4 Drug-induced thyroiditis	0.625	0.374	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.625	0.374	0.000
E06.0 Acute thyroiditis	0.625	0.374	0.000
E50-E64 Other nutritional deficiencies	0.623	0.377	0.000
E40-E46 Malnutrition	0.621	0.379	0.000
I05.8 Other mitral valve diseases	0.620	0.380	0.000
E26 Hyperaldosteronism	0.617	0.382	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.616	0.383	0.000
E27.8 Other specified disorders of adrenal gland	0.614	0.386	0.000
I77.2 Rupture of artery	0.610	0.390	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.390	0.609
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.608	0.392	0.000
E23.1 Drug-induced hypopituitarism	0.608	0.392	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.604	0.396	0.000
E20.1 Pseudohypoparathyroidism	0.604	0.396	0.000
E15 Nondiabetic hypoglycaemic coma	0.603	0.397	0.000
I72 Other aneurysm	0.603	0.397	0.000
E05.8 Other thyrotoxicosis	0.589	0.411	0.000
I77.5 Necrosis of artery	0.581	0.419	0.000
I77.4 Coeliac artery compression syndrome	0.581	0.419	0.000
I77.3 Arterial fibromuscular dysplasia	0.581	0.419	0.000
C76.1 Thorax	0.000	0.423	0.577
C76.3 Pelvis	0.000	0.426	0.574
I13.9 Hypertensive heart and renal disease, unspecified	0.570	0.430	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.570	0.430	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.570	0.430	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.569	0.431	0.000
I20.1 Angina pectoris with documented spasm	0.568	0.432	0.000
E13 Other specified diabetes mellitus	0.567	0.433	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.435	0.565
C76.7 Other ill-defined sites	0.000	0.435	0.565
C76.5 Lower limb	0.000	0.435	0.565
C76.4 Upper limb	0.000	0.435	0.565
Z95.0 Presence of cardiac pacemaker	0.565	0.435	0.000
E27.5 Adrenomedullary hyperfunction	0.556	0.444	0.000
E27.0 Other adrenocortical overactivity	0.556	0.444	0.000
C76.2 Abdomen	0.000	0.446	0.553
E07 Other disorders of thyroid	0.553	0.447	0.000
E28.3 Primary ovarian failure	0.552	0.448	0.000
I07.1 Tricuspid insufficiency	0.551	0.449	0.000
E34 Other endocrine disorders	0.551	0.449	0.000
E20.8 Other hypoparathyroidism	0.550	0.450	0.000
E20.0 Idiopathic hypoparathyroidism	0.550	0.450	0.000
I77.0 Arteriovenous fistula, acquired	0.545	0.455	0.000
I77.8 Other specified disorders of arteries and arterioles	0.544	0.456	0.000
I08 Multiple valve diseases	0.544	0.456	0.000
I74.8 Embolism and thrombosis of other arteries	0.543	0.457	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.541	0.459	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.540	0.460	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.533	0.467	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.533	0.467	0.000
E16.4 Abnormal secretion of gastrin	0.533	0.467	0.000
E16.3 Increased secretion of glucagon	0.533	0.467	0.000
I12.9 Hypertensive renal disease without renal failure	0.533	0.467	0.000
E14 Unspecified diabetes mellitus	0.531	0.469	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.471	0.529
I70.2 Atherosclerosis of arteries of the extremities	0.528	0.472	0.000
I97.0 Postcardiotomy syndrome	0.525	0.475	0.000
I11 Hypertensive heart disease	0.524	0.476	0.000
I79.1 Aortitis in diseases classified elsewhere	0.516	0.484	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.516	0.484	0.000
I72.2 Aneurysm of renal artery	0.516	0.484	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.515	0.485	0.000
E22.8 Other hyperfunction of pituitary gland	0.515	0.485	0.000
I15.0 Renovascular hypertension	0.514	0.486	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.509	0.491	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.509	0.491	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.509	0.491	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.509	0.491	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.509	0.491	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.509	0.491	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.509	0.491	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.509	0.491	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.508	0.492	0.000
E61 Deficiency of other nutrient elements	0.507	0.493	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.507	0.493	0.000
E16.1 Other hypoglycaemia	0.502	0.497	0.000
E12.9 Without complications	0.502	0.498	0.000
E12.8 With unspecified complications	0.502	0.498	0.000
E12.7 With multiple complications	0.502	0.498	0.000
E12.6 With other specified complications	0.502	0.498	0.000
E12.5 With peripheral circulatory complications	0.502	0.498	0.000
E12.4 With neurological complications	0.502	0.498	0.000
E12.3 With ophthalmic complications	0.502	0.498	0.000
E12.2 With renal complications	0.502	0.498	0.000
E12.1 With ketoacidosis	0.502	0.498	0.000
E12.0 With coma	0.502	0.498	0.000
I15.1 Hypertension secondary to other renal disorders	0.501	0.499	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.500	0.500	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.496	0.504	0.000
I07.9 Tricuspid valve disease, unspecified	0.495	0.504	0.000
I07.8 Other tricuspid valve diseases	0.495	0.504	0.000
I07.2 Tricuspid stenosis with insufficiency	0.495	0.504	0.000
I07.0 Tricuspid stenosis	0.495	0.504	0.000
I28 Other diseases of pulmonary vessels	0.493	0.507	0.000
E31.0 Autoimmune polyglandular failure	0.492	0.508	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.509	0.491
E16.0 Drug-induced hypoglycaemia without coma	0.490	0.510	0.000
E58 Dietary calcium deficiency	0.490	0.510	0.000
I15.8 Other secondary hypertension	0.489	0.511	0.000
I09 Other rheumatic heart diseases	0.488	0.511	0.001
I08.0 Disorders of both mitral and aortic valves	0.488	0.512	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.513	0.487
E29 Testicular dysfunction	0.484	0.515	0.000
I15.2 Hypertension secondary to endocrine disorders	0.484	0.516	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.481	0.518	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.520	0.480
I72.4 Aneurysm of artery of lower extremity	0.480	0.520	0.000
I70.9 Generalised and unspecified atherosclerosis	0.476	0.524	0.000
E31.9 Polyglandular dysfunction, unspecified	0.474	0.526	0.000
E31.8 Other polyglandular dysfunction	0.474	0.526	0.000
E31.1 Polyglandular hyperfunction	0.474	0.526	0.000
I26 Pulmonary embolism	0.471	0.529	0.000
E25.9 Adrenogenital disorder, unspecified	0.469	0.531	0.000
E25.8 Other adrenogenital disorders	0.469	0.531	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.468	0.531	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.468	0.531	0.000
I98.0 Cardiovascular syphilis	0.468	0.531	0.000
I70.8 Atherosclerosis of other arteries	0.468	0.532	0.000
E28.9 Ovarian dysfunction, unspecified	0.465	0.535	0.000
E28.8 Other ovarian dysfunction	0.465	0.535	0.000
E28.1 Androgen excess	0.465	0.535	0.000
E28.0 Oestrogen excess	0.465	0.535	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.535	0.465
E30.9 Disorder of puberty, unspecified	0.460	0.540	0.000
E30.8 Other disorders of puberty	0.460	0.540	0.000
E30.1 Precocious puberty	0.460	0.540	0.000
E30.0 Delayed puberty	0.460	0.540	0.000
E32.9 Disease of thymus, unspecified	0.460	0.540	0.000
E32.8 Other diseases of thymus	0.460	0.540	0.000
E32.1 Abscess of thymus	0.460	0.540	0.000
E32.0 Persistent hyperplasia of thymus	0.460	0.540	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.460	0.540	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.460	0.540	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.460	0.540	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.460	0.540	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.541	0.459
I06.0 Rheumatic aortic stenosis	0.456	0.544	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.456	0.544	0.000
I06.8 Other rheumatic aortic valve diseases	0.456	0.544	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.456	0.544	0.000
I06.1 Rheumatic aortic insufficiency	0.456	0.544	0.000
I02 Rheumatic chorea	0.455	0.545	0.000
I01 Rheumatic fever with heart involvement	0.455	0.545	0.000
I81 Portal vein thrombosis	0.455	0.545	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.454	0.546	0.000
I85 Oesophageal varices	0.454	0.546	0.000
E51 Thiamine deficiency	0.453	0.546	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.452	0.548	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.548	0.452
I70.1 Atherosclerosis of renal artery	0.451	0.549	0.000
E24 Cushing's syndrome	0.451	0.549	0.000
I87 Other disorders of veins	0.450	0.550	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.447	0.553	0.000
E63 Other nutritional deficiencies	0.447	0.553	0.000
E50 Vitamin A deficiency	0.447	0.553	0.000
E60 Dietary zinc deficiency	0.447	0.553	0.000
E59 Dietary selenium deficiency	0.447	0.553	0.000
E54 Ascorbic acid deficiency	0.447	0.553	0.000
E52 Niacin deficiency [pellagra]	0.447	0.553	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.445	0.554	0.000
E45 Retarded development following protein-energy malnutrition	0.445	0.554	0.000
E43 Unspecified severe protein-energy malnutrition	0.445	0.554	0.000
E42 Marasmic kwashiorkor	0.445	0.554	0.000
E41 Nutritional marasmus	0.445	0.554	0.000
E40 Kwashiorkor	0.445	0.554	0.000
E26.8 Other hyperaldosteronism	0.443	0.557	0.000
E26.1 Secondary hyperaldosteronism	0.443	0.557	0.000
E61.1 Iron deficiency	0.443	0.557	0.000
I85.0 Oesophageal varices with bleeding	0.440	0.560	0.000
I87.8 Other specified disorders of veins	0.439	0.561	0.000
I97.1 Other functional disturbances following cardiac surgery	0.438	0.562	0.000
I72.8 Aneurysm of other specified arteries	0.437	0.563	0.000
D12.6 Colon, unspecified	0.000	0.564	0.436
E26.0 Primary hyperaldosteronism	0.435	0.564	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.432	0.568	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.432	0.568	0.000
I05.9 Mitral valve disease, unspecified	0.429	0.571	0.000
E13.3 With ophthalmic complications	0.427	0.573	0.000
E26.9 Hyperaldosteronism, unspecified	0.426	0.574	0.000
D12.2 Ascending colon	0.000	0.575	0.425
E27.3 Drug-induced adrenocortical insufficiency	0.423	0.577	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.421	0.579	0.000
E14.4 With neurological complications	0.420	0.580	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.581	0.419
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.419	0.581	0.000
I08.9 Multiple valve disease, unspecified	0.417	0.583	0.000
E14.3 With ophthalmic complications	0.417	0.583	0.000
E27.9 Disorder of adrenal gland, unspecified	0.415	0.584	0.000
E56 Other vitamin deficiencies	0.414	0.586	0.000
E34.0 Carcinoid syndrome	0.412	0.588	0.000
I15.9 Seconday hypertension, unspecified	0.408	0.591	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.001	0.592	0.408
C50.9 Breast, unspecified	0.000	0.592	0.408
C50 Malignant neoplasm of breast	0.000	0.592	0.408
E13.8 With unspecified complications	0.406	0.593	0.000
E13.7 With multiple complications	0.406	0.593	0.000
E13.6 With other specified complications	0.406	0.593	0.000
E13.5 With peripheral circulatory complications	0.406	0.593	0.000
E13.4 With neurological complications	0.406	0.593	0.000
E13.2 With renal complications	0.406	0.593	0.000
E13.1 With ketoacidosis	0.406	0.593	0.000
E13.0 With coma	0.406	0.593	0.000
E14.0 With coma	0.406	0.594	0.000
E07.9 Disorder of thyroid, unspecified	0.401	0.599	0.000
I72.1 Aneurysm of artery of upper extremity	0.399	0.601	0.000
I71 Aortic aneurysm and dissection	0.397	0.603	0.000
I78 Diseases of capillaries	0.396	0.603	0.001
E07.1 Dyshormogenetic goitre	0.396	0.604	0.000
E07.0 Hypersecretion of calcitonin	0.396	0.604	0.000
I28.8 Other specified diseases of pulmonary vessels	0.396	0.604	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.395	0.604	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.395	0.605	0.000
E34.5 Androgen resistance syndrome	0.395	0.605	0.000
E34.4 Constitutional tall stature	0.395	0.605	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.395	0.605	0.000
E34.1 Other hypersecretion of intestinal hormones	0.395	0.605	0.000
E34.3 Short stature, not elsewhere classified	0.394	0.606	0.000
E14.6 With other specified complications	0.394	0.606	0.000
C50.1 Central portion of breast	0.000	0.606	0.394
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.393	0.607	0.000
C50.8 Overlapping lesion of breast	0.000	0.608	0.392
E14.2 Withrenal complications	0.390	0.610	0.000
C50.4 Upper-outer quadrant of breast	0.000	0.610	0.390
I08.1 Disorders of both mitral and tricuspid valves	0.387	0.613	0.000
D12.5 Sigmoid colon	0.000	0.614	0.386
I35 Nonrheumatic aortic valve disorders	0.386	0.614	0.000
E23.7 Disorder of pituitary gland, unspecified	0.385	0.614	0.001
I72.9 Aneurysm of unspecified site	0.382	0.617	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.382	0.618	0.000
E14.7 With multiple complications	0.381	0.619	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.381	0.619	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.378	0.622	0.000
I30-I52 Other forms of heart disease	0.376	0.624	0.000
E14.5 With peripheral circulatory complications	0.376	0.624	0.000
I00 Rheumatic fever without mention of heart involvement	0.373	0.627	0.000
I72.0 Aneurysm of carotid artery	0.373	0.627	0.000
I70.0 Atherosclerosis of aorta	0.369	0.631	0.000
E14.8 With unspecified complications	0.368	0.632	0.000
D12.9 Anus and anal canal	0.000	0.634	0.366
E46 Unspecified protein-energy malnutrition	0.366	0.634	0.000
I86 Varicose veins of other sites	0.366	0.634	0.000
E61.9 Deficiency of nutrient element, unspecified	0.364	0.636	0.000
E61.8 Deficiency of other specified nutrient elements	0.364	0.636	0.000
E61.7 Deficiency of multiple nutrient elements	0.364	0.636	0.000
E61.6 Vanadium deficiency	0.364	0.636	0.000
E61.5 Molybdenum deficiency	0.364	0.636	0.000
E61.4 Chromium deficiency	0.364	0.636	0.000
E61.3 Manganese deficiency	0.364	0.636	0.000
E61.0 Copper deficiency	0.364	0.636	0.000
I35.0 Aortic (valve) stenosis	0.354	0.646	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.354	0.646	0.000
I28.1 Aneurysm of pulmonary artery	0.354	0.646	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.354	0.646	0.000
C50.0 Nipple and areola	0.000	0.649	0.351
I09.8 Other specified rheumatic heart diseases	0.350	0.649	0.001
I09.2 Chronic rheumatic pericarditis	0.350	0.649	0.001
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.350	0.649	0.001
I09.0 Rheumatic myocarditis	0.350	0.649	0.001
I36 Nonrheumatic tricuspid valve disorders	0.350	0.650	0.000
E34.9 Endocrine disorder, unspecified	0.349	0.650	0.000
I78.8 Other diseases of capillaries	0.348	0.651	0.000
E29.8 Other testicular dysfunction	0.347	0.652	0.000
E29.0 Testicular hyperfunction	0.347	0.652	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.347	0.653	0.000
E29.9 Testicular dysfunction, unspecified	0.345	0.655	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.344	0.656	0.000
E53 Deficiency of other B group vitamins	0.343	0.657	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.341	0.658	0.000
I86.4 Gastric varices	0.340	0.660	0.000
E55 Vitamin D deficiency	0.340	0.660	0.000
E34.8 Other specified endocrine disorders	0.336	0.664	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.335	0.664	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.334	0.666	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.333	0.667	0.000
I82 Other venous embolism and thrombosis	0.333	0.667	0.000
I88 Nonspecific lymphadenitis	0.333	0.667	0.000
E51.2 Wernicke's encephalopathy	0.332	0.668	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.331	0.669	0.000
Z82.3 Family history of stroke	0.330	0.670	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.329	0.670	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.328	0.672	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.326	0.673	0.000
I01.8 Other acute rheumatic heart disease	0.326	0.673	0.000
I01.2 Acute rheumatic myocarditis	0.326	0.673	0.000
I01.1 Acute rheumatic endocarditis	0.326	0.673	0.000
I01.0 Acute rheumatic pericarditis	0.326	0.673	0.000
I02.9 Rheumatic chorea without heart involvement	0.326	0.673	0.000
I02.0 Rheumatic chorea with heart involvement	0.326	0.673	0.000
E51.9 Thiamine deficiency, unspecified	0.325	0.675	0.000
E51.8 Other manifestations of thiamine deficiency	0.325	0.675	0.000
E51.1 Beriberi	0.325	0.675	0.000
E61.2 Magnesium deficiency	0.324	0.676	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.323	0.676	0.000
E24.8 Other Cushing's syndrome	0.323	0.676	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.323	0.676	0.000
E24.3 Ectopic ACTH syndrome	0.323	0.676	0.000
E24.1 Nelson's syndrome	0.323	0.676	0.000
I87.0 Postphlebitic syndrome	0.323	0.677	0.000
E50.9 Vitamin A deficiency, unspecified	0.320	0.679	0.000
E50.8 Other manifestations of vitamin A deficiency	0.320	0.679	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.320	0.679	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.320	0.679	0.000
E50.5 Vitamin A deficiency with night blindness	0.320	0.679	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.320	0.679	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.320	0.679	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.320	0.679	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.320	0.679	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.320	0.679	0.000
E63.9 Nutritional deficiency, unspecified	0.320	0.679	0.000
E63.8 Other specified nutritional deficiencies	0.320	0.679	0.000
E63.1 Imbalance of constituents of food intake	0.320	0.679	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.320	0.679	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.320	0.679	0.000
E64.8 Sequelae of other nutritional deficiencies	0.320	0.679	0.000
E64.3 Sequelae of rickets	0.320	0.679	0.000
E64.2 Sequelae of vitamin C deficiency	0.320	0.679	0.000
E64.1 Sequelae of vitamin A deficiency	0.320	0.679	0.000
E64.0 Sequelae of protein-energy malnutrition	0.320	0.679	0.000
E44.1 Mild protein-energy malnutrition	0.319	0.680	0.000
E44.0 Moderate protein-energy malnutrition	0.319	0.680	0.000
E28.2 Polycystic ovarian syndrome	0.314	0.686	0.000
E24.2 Drug-induced Cushing's syndrome	0.314	0.686	0.000
D12.3 Transverse colon	0.000	0.688	0.312
E22.0 Acromegaly and pituitary gigantism	0.309	0.691	0.000
I33 Acute and subacute endocarditis	0.303	0.696	0.000
I35.1 Aortic (valve) insufficiency	0.303	0.697	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.698	0.302
I35.8 Other aortic valve disorders	0.302	0.698	0.000
I87.9 Disorder of vein, unspecified	0.302	0.698	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.301	0.699	0.000
E14.1 With ketoacidosis	0.301	0.699	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.299	0.701	0.000
E65-E68 Obesity and other hyperalimentation	0.298	0.702	0.000
E56.9 Vitamin deficiency, unspecified	0.297	0.703	0.000
E56.8 Deficiency of other vitamins	0.297	0.703	0.000
E56.0 Deficiency of vitamin E	0.297	0.703	0.000
I20.0 Unstable angina	0.296	0.704	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations