TreeWAS – Variant ID: rs1773285

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
I10 Essential (primary) hypertension	0.000	0.026	0.974
E83 Disorders of mineral metabolism	0.000	0.405	0.595
E83.3 Disorders of phosphorus metabolism	0.000	0.521	0.479
E83.4 Disorders of magnesium metabolism	0.000	0.547	0.453
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.573	0.427
E83.8 Other disorders of mineral metabolism	0.000	0.573	0.427
E83.2 Disorders of zinc metabolism	0.000	0.573	0.427
E83.0 Disorders of copper metabolism	0.000	0.573	0.427
E83.5 Disorders of calcium metabolism	0.000	0.599	0.401
I10-I15 Hypertensive diseases	0.000	0.706	0.294
I11 Hypertensive heart disease	0.000	0.764	0.235
I13 Hypertensive heart and renal disease	0.000	0.789	0.211
K75 Other inflammatory liver diseases	0.000	0.799	0.201
K70-K77 Diseases of liver	0.000	0.805	0.195
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.805	0.195
K75.4 Autoimmune hepatitis	0.000	0.809	0.191
K70 Alcoholic liver disease	0.000	0.810	0.190
E80.4 Gilbert's syndrome	0.000	0.812	0.188
K75.9 Inflammatory liver disease, unspecified	0.000	0.815	0.185
I12 Hypertensive renal disease	0.000	0.819	0.181
K74 Fibrosis and cirrhosis of liver	0.000	0.824	0.176
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.824	0.176
K75.8 Other specified inflammatory liver diseases	0.000	0.830	0.170
K70.9 Alcoholic liver disease, unspecified	0.000	0.831	0.169
K70.4 Alcoholic hepatic failure	0.000	0.832	0.168
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.833	0.167
E70-E90 Metabolic disorders	0.000	0.833	0.167
K75.0 Abscess of liver	0.000	0.833	0.167
K74.6 Other and unspecified cirrhosis of liver	0.000	0.839	0.161
K73 Chronic hepatitis, not elsewhere classified	0.000	0.841	0.158
K74.0 Hepatic fibrosis	0.000	0.848	0.152
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.849	0.151
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.849	0.151
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.849	0.151
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.849	0.151
K72 Hepatic failure, not elsewhere classified	0.000	0.849	0.151
K70.0 Alcoholic fatty liver	0.000	0.850	0.150
K70.3 Alcoholic cirrhosis of liver	0.000	0.850	0.150
I12.9 Hypertensive renal disease without renal failure	0.000	0.852	0.148
I15 Secondary hypertension	0.000	0.853	0.147
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.856	0.144
K75.2 Nonspecific reactive hepatitis	0.000	0.856	0.144
K75.1 Phlebitis of portal vein	0.000	0.856	0.144
K77 Liver disorders in diseases classified elsewhere	0.000	0.860	0.140
K71 Toxic liver disease	0.000	0.860	0.140
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.861	0.139
K76 Other diseases of liver	0.000	0.863	0.137
E73 Lactose intolerance	0.000	0.864	0.136
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.867	0.133
K70.1 Alcoholic hepatitis	0.000	0.870	0.130
K76.9 Liver disease, unspecified	0.000	0.871	0.129
E80.6 Other disorders of bilirubin metabolism	0.000	0.871	0.129
K72.0 Acute and subacute hepatic failure	0.000	0.872	0.128
K74.4 Secondary biliary cirrhosis	0.000	0.874	0.126
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.874	0.126
K74.1 Hepatic sclerosis	0.000	0.874	0.126
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.874	0.126
E80.5 Crigler-Najjar syndrome	0.000	0.874	0.126
E80.3 Defects of catalase and peroxydase	0.000	0.874	0.126
E80.2 Other porphyria	0.000	0.874	0.126
E80.1 Porphyria cutanea tarda	0.000	0.874	0.126
E80.0 Hereditary erythropoietic porphyria	0.000	0.874	0.126
E74 Other disorders of carbohydrate metabolism	0.000	0.878	0.122
E84 Cystic fibrosis	0.000	0.880	0.120
E77 Disorders of glycoprotein metabolism	0.000	0.880	0.120
E76 Disorders of glycosaminoglycan metabolism	0.000	0.880	0.120
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.880	0.120
E72 Other disorders of amino-acid metabolism	0.000	0.880	0.120
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.880	0.120
E70 Disorders of aromatic amino-acid metabolism	0.000	0.880	0.120
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.880	0.120
E79 Disorders of purine and pyrimidine metabolism	0.000	0.881	0.119
E73.9 Lactose intolerance, unspecified	0.000	0.886	0.114
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.886	0.114
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.886	0.114
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.886	0.114
K73.9 Chronic hepatitis, unspecified	0.000	0.887	0.113
K76.6 Portal hypertension	0.000	0.888	0.112
K74.5 Biliary cirrhosis, unspecified	0.000	0.888	0.111
K72.1 Chronic hepatic failure	0.000	0.891	0.109
K74.3 Primary biliary cirrhosis	0.000	0.894	0.106
I15.8 Other secondary hypertension	0.000	0.894	0.105
I15.2 Hypertension secondary to endocrine disorders	0.000	0.894	0.105
I15.0 Renovascular hypertension	0.000	0.894	0.105
K71.9 Toxic liver disease, unspecified	0.000	0.899	0.101
K71.8 Toxic liver disease with other disorders of liver	0.000	0.899	0.101
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.899	0.101
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.899	0.101
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.899	0.101
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.899	0.101
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.899	0.101
K71.2 Toxic liver disease with acute hepatitis	0.000	0.899	0.101
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.899	0.101
K71.0 Toxic liver disease with cholestasis	0.000	0.899	0.101
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.899	0.101
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.899	0.101
K76.5 Hepatic veno-occlusive disease	0.000	0.901	0.098
K76.4 Peliosis hepatis	0.000	0.901	0.098
K76.3 Infarction of liver	0.000	0.901	0.098
K76.2 Central haemorrhagic necrosis of liver	0.000	0.901	0.098
E73.8 Other lactose intolerance	0.000	0.902	0.098
E73.1 Secondary lactase deficiency	0.000	0.902	0.098
E73.0 Congenital lactase deficiency	0.000	0.902	0.098
K72.9 Hepatic failure, unspecified	0.000	0.906	0.094
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.911	0.089
I15.9 Seconday hypertension, unspecified	0.001	0.912	0.087
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.912	0.087
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.912	0.087
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.912	0.087
E74.2 Disorders of galactose metabolism	0.000	0.912	0.087
E74.1 Disorders of fructose metabolism	0.000	0.912	0.087
E74.0 Glycogen storage disease	0.000	0.912	0.087
K76.7 Hepatorenal syndrome	0.000	0.914	0.086
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.914	0.086
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.914	0.086
E70.3 Albinism	0.000	0.914	0.086
E70.2 Disorders of tyrosine metabolism	0.000	0.914	0.086
E70.1 Other hyperphenylalaninaemias	0.000	0.914	0.086
E70.0 Classical phenylketonuria	0.000	0.914	0.086
E71.3 Disorders of fatty-acid metabolism	0.000	0.914	0.086
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.914	0.086
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.914	0.086
E71.0 Maple-syrup-urine disease	0.000	0.914	0.086
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.914	0.086
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.914	0.086
E72.5 Disorders of glycine metabolism	0.000	0.914	0.086
E72.4 Disorders of ornithine metabolism	0.000	0.914	0.086
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.914	0.086
E72.2 Disorders of urea cycle metabolism	0.000	0.914	0.086
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.914	0.086
E72.0 Disorders of amino-acid transport	0.000	0.914	0.086
E75.6 Lipid storage disorder, unspecified	0.000	0.914	0.086
E75.5 Other lipid storage disorders	0.000	0.914	0.086
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.914	0.086
E75.3 Sphingolipidosis, unspecified	0.000	0.914	0.086
E75.2 Other sphingolipidosis	0.000	0.914	0.086
E75.1 Other gangliosidosis	0.000	0.914	0.086
E75.0 GM2 gangliosidosis	0.000	0.914	0.086
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.914	0.086
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.914	0.086
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.914	0.086
E76.2 Other mucopolysaccharidoses	0.000	0.914	0.086
E76.1 Mucopolysaccharidosis, type II	0.000	0.914	0.086
E76.0 Mucopolysaccharidosis, type I	0.000	0.914	0.086
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.914	0.086
E77.8 Other disorders of glycoprotein metabolism	0.000	0.914	0.086
E77.1 Defects in glycoprotein degradation	0.000	0.914	0.086
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.914	0.086
E84.9 Cystic fibrosis, unspecified	0.000	0.914	0.086
E84.8 Cystic fibrosis with other manifestations	0.000	0.914	0.086
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.914	0.086
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.914	0.086
E88 Other metabolic disorders	0.000	0.914	0.086
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.915	0.085
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.915	0.085
E79.1 Lesch-Nyhan syndrome	0.000	0.915	0.085
K76.1 Chronic passive congestion of liver	0.000	0.915	0.085
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.916	0.084
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.919	0.081
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.924	0.076
I15.1 Hypertension secondary to other renal disorders	0.001	0.926	0.073
E89.3 Postprocedural hypopituitarism	0.000	0.929	0.071
E85 Amyloidosis	0.001	0.937	0.062
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.937	0.062
E88.8 Other specified metabolic disorders	0.000	0.938	0.062
E88.3 Tumour lysis syndrome	0.000	0.938	0.062
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.942	0.058
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.942	0.058
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.942	0.058
E89.5 Postprocedural testicular hypofunction	0.000	0.942	0.058
E88.2 Lipomatosis, not elsewhere classified	0.000	0.942	0.058
E89.4 Postprocedural ovarian failure	0.000	0.943	0.057
I12.0 Hypertensive renal disease with renal failure	0.000	0.944	0.056
E88.9 Metabolic disorder, unspecified	0.000	0.948	0.051
E89.1 Postprocedural hypoinsulinaemia	0.000	0.949	0.051
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.950	0.050
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.951	0.048
E89.2 Postprocedural hypoparathyroidism	0.000	0.954	0.046
E85.8 Other amyloidosis	0.001	0.954	0.045
E85.2 Heredofamilial amyloidosis, unspecified	0.001	0.954	0.045
E85.1 Neuropathic heredofamilial amyloidosis	0.001	0.954	0.045
E85.0 Nonneuropathic heredofamilial amyloidosis	0.001	0.954	0.045
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.958	0.042
E78.1 Pure hyperglyceridaemia	0.000	0.960	0.040
E85.3 Secondary systemic amyloidosis	0.001	0.960	0.039
M19.94 Arthrosis, unspecified (Hand)	0.039	0.961	0.000
E85.9 Amyloidosis, unspecified	0.001	0.961	0.038
E78.5 Hyperlipidaemia, unspecified	0.000	0.962	0.038
E78.6 Lipoprotein deficiency	0.000	0.964	0.036
E78.3 Hyperchylomicronaemia	0.000	0.964	0.036
K76.8 Other specified diseases of liver	0.000	0.967	0.033
E78.8 Other disorders of lipoprotein metabolism	0.000	0.968	0.032
E78.4 Other hyperlipidaemia	0.000	0.971	0.029
O70.1 Second degree perineal laceration during delivery	0.026	0.974	0.000
O70 Perineal laceration during delivery	0.026	0.974	0.000
O70.0 First degree perineal laceration during delivery	0.025	0.975	0.000
O03 Spontaneous abortion	0.024	0.976	0.000
O60-O75 Complications of labour and delivery	0.023	0.977	0.000
E85.4 Organ-limited amyloidosis	0.002	0.977	0.022
O62.2 Other uterine inertia	0.023	0.977	0.000
O03.4 Incomplete, without complication	0.023	0.977	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.023	0.977	0.000
O62 Abnormalities of forces of labour	0.023	0.977	0.000
O03.9 Complete or unspecified, without complication	0.023	0.977	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.022	0.978	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.979	0.021
O00-O08 Pregnancy with abortive outcome	0.021	0.979	0.000
O70.2 Third degree perineal laceration during delivery	0.021	0.979	0.000
E87.3 Alkalosis	0.000	0.979	0.021
O24 Diabetes mellitus in pregnancy	0.021	0.979	0.000
O80-O84 Delivery	0.021	0.979	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.020	0.980	0.000
O81 Single delivery by forceps and vacuum extractor	0.020	0.980	0.000
O85-O92 Complications predominantly related to the puerperium	0.019	0.981	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.019	0.981	0.000
O70.3 Fourth degree perineal laceration during delivery	0.019	0.981	0.000
O62.0 Primary inadequate contractions	0.019	0.981	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.982	0.018
O03.3 Incomplete, with other and unspecified complications	0.018	0.982	0.000
O28 Abnormal findings on antenatal screening of mother	0.018	0.982	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.018	0.982	0.000
O70.9 Perineal laceration during delivery, unspecified	0.018	0.982	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.018	0.982	0.000
O61 Failed induction of labour	0.018	0.982	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.982	0.018
O94-O99 Other obstetric conditions, not elsewhere classified	0.018	0.982	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.982	0.018
O81.3 Other and unspecified forceps delivery	0.017	0.982	0.000
O03.7 Complete or unspecified, complicated by embolism	0.017	0.982	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.017	0.982	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.017	0.982	0.000
O03.2 Incomplete, complicated by embolism	0.017	0.982	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.017	0.982	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.017	0.982	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.017	0.982	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.017	0.983	0.000
O21 Excessive vomiting in pregnancy	0.017	0.983	0.000
O74 Complications of anaesthesia during labour and delivery	0.017	0.983	0.000
O81.0 Low forceps delivery	0.017	0.983	0.000
O66 Other obstructed labour	0.017	0.983	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.017	0.983	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.017	0.983	0.000
O60 Preterm delivery	0.017	0.983	0.000
O62.1 Secondary uterine inertia	0.017	0.983	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.017	0.983	0.000
O26.9 Pregnancy-related condition, unspecified	0.016	0.984	0.000
O62.9 Abnormality of forces of labour, unspecified	0.016	0.984	0.000
O62.8 Other abnormalities of forces of labour	0.016	0.984	0.000
O86 Other puerperal infections	0.016	0.984	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.016	0.984	0.000
O81.4 Vacuum extractor delivery	0.016	0.984	0.000
O29 Complications of anaesthesia during pregnancy	0.016	0.984	0.000
O25 Malnutrition in pregnancy	0.016	0.984	0.000
O26.2 Pregnancy care of habitual aborter	0.016	0.984	0.000
O20 Haemorrhage in early pregnancy	0.016	0.984	0.000
E78.2 Mixed hyperlipidaemia	0.001	0.984	0.016
O22 Venous complications in pregnancy	0.016	0.984	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.016	0.984	0.000
O82 Single delivery by Caesarean section	0.016	0.984	0.000
E87.4 Mixed disorder of acid-base balance	0.000	0.984	0.016
O71 Other obstetric trauma	0.016	0.984	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.015	0.984	0.000
O07 Failed attempted abortion	0.015	0.984	0.000
O06 Unspecified abortion	0.015	0.984	0.000
O05 Other abortion	0.015	0.984	0.000
O01 Hydatidiform mole	0.015	0.984	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.984	0.016
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.016	0.984	0.000
O85 Puerperal sepsis	0.015	0.984	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.015	0.985	0.000
O73 Retained placenta and membranes, without haemorrhage	0.015	0.985	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.015	0.985	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.015	0.985	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.015	0.985	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.015	0.985	0.000
O84 Multiple delivery	0.015	0.985	0.000
O83 Other assisted single delivery	0.015	0.985	0.000
O62.3 Precipitate labour	0.015	0.985	0.000
O87 Venous complications in the puerperium	0.015	0.985	0.000
O72 Postpartum haemorrhage	0.015	0.985	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.014	0.985	0.000
O81.2 Mid-cavity forceps with rotation	0.014	0.985	0.000
O81.1 Mid-cavity forceps delivery	0.014	0.985	0.000
O86.4 Pyrexia of unknown origin following delivery	0.014	0.985	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.014	0.986	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.014	0.986	0.000
O14.9 Preeclampsia, unspecified	0.014	0.986	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.014	0.986	0.000
O89 Complications of anaesthesia during the puerperium	0.014	0.986	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.014	0.986	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.986	0.014
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.014	0.986	0.000
O91 Infections of breast associated with childbirth	0.014	0.986	0.000
O88 Obstetric embolism	0.014	0.986	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.014	0.986	0.000
O26.5 Maternal hypotension syndrome	0.014	0.986	0.000
O26.4 Herpes gestationis	0.014	0.986	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.014	0.986	0.000
O26.1 Low weight gain in pregnancy	0.014	0.986	0.000
O26.0 Excessive weight gain in pregnancy	0.014	0.986	0.000
O61.0 Failed medical induction of labour	0.014	0.986	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.014	0.986	0.000
O23 Infections of genito-urinary tract in pregnancy	0.014	0.986	0.000
E86 Volume depletion	0.000	0.986	0.014
A49 Bacterial infection of unspecified site	0.000	0.986	0.014
O21.9 Vomiting of pregnancy, unspecified	0.014	0.986	0.000
A49.8 Other bacterial infections of unspecified site	0.000	0.986	0.013
O72.2 Delayed and secondary postpartum haemorrhage	0.013	0.987	0.000
A49.1 Streptococcal infection, unspecified	0.000	0.987	0.013
O67.9 Intrapartum haemorrhage, unspecified	0.013	0.987	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.013	0.987	0.000
M35.3 Polymyalgia rheumatica	0.000	0.987	0.013
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.013	0.987	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.013	0.987	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.013	0.987	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.013	0.987	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.013	0.987	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.013	0.987	0.000
O21.8 Other vomiting complicating pregnancy	0.013	0.987	0.000
O21.2 Late vomiting of pregnancy	0.013	0.987	0.000
O61.9 Failed induction of labour, unspecified	0.013	0.987	0.000
O61.8 Other failed induction of labour	0.013	0.987	0.000
O61.1 Failed instrumental induction of labour	0.013	0.987	0.000
O86.2 Urinary tract infection following delivery	0.013	0.987	0.000
O20.8 Other haemorrhage in early pregnancy	0.013	0.987	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.013	0.987	0.000
O97 Death from sequelae of direct obstetric causes	0.013	0.987	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.013	0.987	0.000
O95 Obstetric death of unspecified cause	0.013	0.987	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.013	0.987	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.013	0.987	0.000
O67.8 Other intrapartum haemorrhage	0.013	0.987	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.013	0.987	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.013	0.987	0.000
E87.2 Acidosis	0.000	0.987	0.013
O02 Other abnormal products of conception	0.013	0.987	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.012	0.987	0.000
O86.1 Other infection of genital tract following delivery	0.012	0.987	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.012	0.987	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.012	0.987	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.012	0.987	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.012	0.987	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.012	0.987	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.012	0.987	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.012	0.987	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.012	0.987	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.012	0.987	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.013	0.987	0.000
O66.4 Failed trial of labour, unspecified	0.012	0.987	0.000
O20.0 Threatened abortion	0.013	0.987	0.000
O66.9 Obstructed labour, unspecified	0.012	0.987	0.000
O66.8 Other specified obstructed labour	0.012	0.987	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.012	0.987	0.000
O66.2 Obstructed labour due to unusually large foetus	0.012	0.987	0.000
O66.1 Obstructed labour due to locked twins	0.012	0.987	0.000
O15 Eclampsia	0.012	0.988	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.012	0.988	0.000
O63 Long labour	0.012	0.988	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.012	0.988	0.000
O60.3 Preterm delivery without spontaneous labour	0.012	0.988	0.000
O60.2 Preterm spontaneous labour with term delivery	0.012	0.988	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.012	0.988	0.000
O60.0 Preterm labour without delivery	0.012	0.988	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.012	0.988	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.012	0.988	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.012	0.988	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.012	0.988	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.012	0.988	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.012	0.988	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.012	0.988	0.000
O65.0 Obstructed labour due to deformed pelvis	0.012	0.988	0.000
O82.9 Delivery by Caesarean section, unspecified	0.012	0.988	0.000
O71.8 Other specified obstetric trauma	0.012	0.988	0.000
O82.0 Delivery by elective Caesarean section	0.012	0.988	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.012	0.988	0.000
O90 Complications of the puerperium, not elsewhere classified	0.012	0.988	0.000
O12.0 Gestational oedema	0.012	0.988	0.000
I63.9 Cerebral infarction, unspecified	0.000	0.988	0.012
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.012	0.988	0.000
O86.8 Other specified puerperal infections	0.012	0.988	0.000
O86.3 Other genito-urinary tract infections following delivery	0.012	0.988	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.012	0.988	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.012	0.988	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.012	0.988	0.000
O29.6 Failed or difficult intubation during pregnancy	0.012	0.988	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.012	0.988	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.012	0.988	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.012	0.988	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.012	0.988	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.012	0.988	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.012	0.988	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.012	0.988	0.000
O22.9 Venous complication in pregnancy, unspecified	0.012	0.988	0.000
O22.8 Other venous complications in pregnancy	0.012	0.988	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.012	0.988	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.012	0.988	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.012	0.988	0.000
O22.1 Genital varices in pregnancy	0.012	0.988	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.012	0.988	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.012	0.988	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.012	0.988	0.000
O82.8 Other single delivery by Caesarean section	0.011	0.988	0.000
O82.2 Delivery by Caesarean hysterectomy	0.011	0.988	0.000
O21.0 Mild hyperemesis gravidarum	0.011	0.988	0.000
I67 Other cerebrovascular diseases	0.000	0.988	0.012
O22.4 Haemorrhoids in pregnancy	0.011	0.988	0.000
O71.9 Obstetric trauma, unspecified	0.011	0.989	0.000
O71.7 Obstetric haematoma of pelvis	0.011	0.989	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.011	0.989	0.000
O71.5 Other obstetric injury to pelvic organs	0.011	0.989	0.000
O71.3 Obstetric laceration of cervix	0.011	0.989	0.000
O71.2 Postpartum inversion of uterus	0.011	0.989	0.000
O71.1 Rupture of uterus during labour	0.011	0.989	0.000
O71.0 Rupture of uterus before onset of labour	0.011	0.989	0.000
O01.9 Hydatidiform mole, unspecified	0.011	0.989	0.000
O01.1 Incomplete and partial hydatidiform mole	0.011	0.989	0.000
O01.0 Classical hydatidiform mole	0.011	0.989	0.000
O05.9 Complete or unspecified, without complication	0.011	0.989	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.011	0.989	0.000
O05.7 Complete or unspecified, complicated by embolism	0.011	0.989	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.011	0.989	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.011	0.989	0.000
O05.4 Incomplete, without complication	0.011	0.989	0.000
O05.3 Incomplete, with other and unspecified complications	0.011	0.989	0.000
O05.2 Incomplete, complicated by embolism	0.011	0.989	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.011	0.989	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.011	0.989	0.000
O06.9 Complete or unspecified, without complication	0.011	0.989	0.000
O06.8 Complete or unspecified, with other and unspecified complications	0.011	0.989	0.000
O06.7 Complete or unspecified, complicated by embolism	0.011	0.989	0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.011	0.989	0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.011	0.989	0.000
O06.4 Incomplete, without complication	0.011	0.989	0.000
O06.3 Incomplete, with other and unspecified complications	0.011	0.989	0.000
O06.2 Incomplete, complicated by embolism	0.011	0.989	0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.011	0.989	0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.011	0.989	0.000
O07.9 Other and unspecified failed attempted abortion, without complication	0.011	0.989	0.000
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.011	0.989	0.000
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.011	0.989	0.000
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.011	0.989	0.000
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.011	0.989	0.000
O07.4 Failed medical abortion, without complication	0.011	0.989	0.000
O07.3 Failed medical abortion, with other and unspecified complications	0.011	0.989	0.000
O07.2 Failed medical abortion, complicated by embolism	0.011	0.989	0.000
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.011	0.989	0.000
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.011	0.989	0.000
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.011	0.989	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.011	0.989	0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.011	0.989	0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.011	0.989	0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.011	0.989	0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.011	0.989	0.000
O08.3 Shock following abortion and ectopic and molar pregnancy	0.011	0.989	0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.011	0.989	0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.011	0.989	0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.011	0.989	0.000
O80 Single spontaneous delivery	0.011	0.989	0.000
O87.2 Haemorrhoids in the puerperium	0.011	0.989	0.000
O14.2 HELLP syndrome	0.011	0.989	0.000
O87.8 Other venous complications in the puerperium	0.011	0.989	0.000
O14.1 Severe preeclampsia	0.011	0.989	0.000
O14.0 Moderate preeclampsia	0.011	0.989	0.000
O00 Ectopic pregnancy	0.011	0.989	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.011	0.989	0.000
O64.5 Obstructed labour due to compound presentation	0.011	0.989	0.000
O64.4 Obstructed labour due to shoulder presentation	0.011	0.989	0.000
O64.3 Obstructed labour due to brow presentation	0.011	0.989	0.000
O64.2 Obstructed labour due to face presentation	0.011	0.989	0.000
I63 Cerebral infarction	0.000	0.989	0.011
O83.9 Assisted single delivery, unspecified	0.011	0.989	0.000
O83.8 Other specified assisted single delivery	0.011	0.989	0.000
O83.4 Destructive operation for delivery	0.011	0.989	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.011	0.989	0.000
O83.2 Other manipulation-assisted delivery	0.011	0.989	0.000
O83.1 Other assisted breech delivery	0.011	0.989	0.000
O83.0 Breech extraction	0.011	0.989	0.000
O84.9 Multiple delivery, unspecified	0.011	0.989	0.000
O84.8 Other multiple delivery	0.011	0.989	0.000
O84.2 Multiple delivery, all by Caesarean section	0.011	0.989	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.011	0.989	0.000
O84.0 Multiple delivery, all spontaneous	0.011	0.989	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.989	0.011
O04 Medical abortion	0.011	0.989	0.000
O87.9 Venous complication in the puerperium, unspecified	0.011	0.989	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.011	0.989	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.011	0.989	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.011	0.989	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.989	0.011
O72.3 Postpartum coagulation defects	0.011	0.989	0.000
O82.1 Delivery by emergency Caesarean section	0.011	0.989	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.989	0.011
O75 Other complications of labour and delivery, not elsewhere classified	0.011	0.989	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.989	0.011
O12.1 Gestational proteinuria	0.011	0.989	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.011	0.989	0.000
E87.6 Hypokalaemia	0.000	0.989	0.011
O23.5 Infections of the genital tract in pregnancy	0.010	0.989	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations