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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17777854
log Bayes Factor = 16.6024
Chromosome 14   position 89,610,698  (GRCh37) Explore rs17777854 on Ensembl!
Variant rs17777854 is part of Cluster X0222

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
F32 Depressive episode
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
F32.9 Depressive episode, unspecified
0.998 0.002 0.000
Chapter II Neoplasms
0.997 0.003 0.000
E00-E07 Disorders of thyroid gland
0.993 0.007 0.000
Chapter XXI Factors influencing health status and contact with health services
0.991 0.009 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.989 0.011 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.986 0.014 0.000
M20-M25 Other joint disorders
0.986 0.014 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.982 0.018 0.000
Chapter XX External causes of morbidity and mortality
0.981 0.019 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.978 0.022 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.978 0.022 0.000
Z13 Special screening examination for other diseases and disorders
0.977 0.023 0.000
Y43 Primarily systemic agents
0.971 0.029 0.000
E04 Other non-toxic goitre
0.965 0.035 0.000
Y43.3 Other antineoplastic drugs
0.965 0.035 0.000
E65-E68 Obesity and other hyperalimentation
0.963 0.037 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.962 0.038 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.961 0.039 0.000
T39.1 4-Aminophenol derivatives
0.960 0.040 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.960 0.040 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.957 0.043 0.000
Chapter IX Diseases of the circulatory system
0.952 0.048 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.948 0.052 0.000
M05-M14 Inflammatory polyarthropathies
0.943 0.057 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.942 0.058 0.000
E66 Obesity
0.937 0.063 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.937 0.063 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.937 0.063 0.000
C77.1 Intrathoracic lymph nodes
0.936 0.064 0.000
E03 Other hypothyroidism
0.933 0.067 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.931 0.069 0.000
D00-D09 In situ neoplasms
0.928 0.072 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.927 0.073 0.000
L60-L75 Disorders of skin appendages
0.921 0.079 0.000
R47-R49 Symptoms and signs involving speech and voice
0.921 0.079 0.000
E66.9 Obesity, unspecified
0.920 0.080 0.000
M23 Internal derangement of knee
0.919 0.081 0.000
E04.2 Non-toxic multinodular goitre
0.919 0.081 0.000
C64-C68 Malignant neoplasms of urinary tract
0.917 0.083 0.000
I20-I25 Ischaemic heart diseases
0.917 0.083 0.000
Z04 Examination and observation for other reasons
0.911 0.089 0.000
Chapter VII Diseases of the eye and adnexa
0.907 0.093 0.000
R26 Abnormalities of gait and mobility
0.905 0.095 0.000
L40-L45 Papulosquamous disorders
0.904 0.096 0.000
E20-E35 Disorders of other endocrine glands
0.902 0.098 0.000
Z13.9 Special screening examination, unspecified
0.901 0.099 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.899 0.101 0.000
S90-S99 Injuries to the ankle and foot
0.894 0.106 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.893 0.107 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.892 0.108 0.000
M45-M49 Spondylopathies
0.890 0.110 0.000
E03.9 Hypothyroidism, unspecified
0.890 0.110 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.888 0.112 0.000
M13 Other arthritis
0.888 0.112 0.000
I20 Angina pectoris
0.886 0.114 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.886 0.114 0.000
E04.9 Non-toxic goitre, unspecified
0.886 0.114 0.000
Z04.8 Examination and observation for other specified reasons
0.886 0.114 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.883 0.117 0.000
S80-S89 Injuries to the knee and lower leg
0.883 0.117 0.000
I10-I15 Hypertensive diseases
0.873 0.127 0.000
L60 Nail disorders
0.873 0.127 0.000
M25 Other joint disorders, not elsewhere classified
0.871 0.129 0.000
F60-F69 Disorders of adult personality and behaviour
0.869 0.131 0.000
M24 Other specific joint derangements
0.866 0.134 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.864 0.136 0.000
F32.1 Moderate depressive episode
0.862 0.138 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.859 0.140 0.000
C60-C63 Malignant neoplasms of male genital organs
0.858 0.142 0.000
H00 Hordeolum and chalazion
0.858 0.142 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.858 0.142 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.856 0.144 0.000
T91 Sequelae of injuries of neck and trunk
0.856 0.144 0.000
R47 Speech disturbances, not elsewhere classified
0.851 0.149 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.850 0.150 0.000
M13.9 Arthritis, unspecified
0.850 0.150 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.846 0.154 0.000
E50-E64 Other nutritional deficiencies
0.845 0.155 0.000
S10-S19 Injuries to the neck
0.844 0.156 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.844 0.156 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.842 0.158 0.000
H00.1 Chalazion
0.842 0.158 0.000
Z73 Problems related to life-management difficulty
0.841 0.159 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.841 0.159 0.000
C77.5 Intrapelvic lymph nodes
0.839 0.161 0.000
L20-L30 Dermatitis and eczema
0.835 0.165 0.000
Chapter X Diseases of the respiratory system
0.834 0.166 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.833 0.167 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.833 0.167 0.000
I20.8 Other forms of angina pectoris
0.832 0.168 0.000
Z74 Problems related to care-provider dependency
0.831 0.169 0.000
L60.0 Ingrowing nail
0.831 0.169 0.000
L40 Psoriasis
0.830 0.170 0.000
R10 Abdominal and pelvic pain
0.830 0.170 0.000
M80-M85 Disorders of bone density and structure
0.825 0.175 0.000
I20.9 Angina pectoris, unspecified
0.825 0.175 0.000
F33 Recurrent depressive disorder
0.824 0.176 0.000
Z72 Problems related to lifestyle
0.824 0.176 0.000
F32.0 Mild depressive episode
0.823 0.177 0.000
M13.94 Arthritis, unspecified (Hand)
0.823 0.177 0.000
C80 Malignant neoplasm without specification of site
0.823 0.177 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.822 0.178 0.000
S00-S09 Injuries to the head
0.822 0.178 0.000
J09-J18 Influenza and pneumonia
0.820 0.180 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.818 0.181 0.000
C77.0 Lymph nodes of head, face and neck
0.817 0.183 0.000
R10.3 Pain localised to other parts of lower abdomen
0.817 0.183 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.816 0.184 0.000
Y52 Agents primarily affecting the cardiovascular system
0.810 0.190 0.000
D60-D64 Aplastic and other anaemias
0.810 0.190 0.000
S92 Fracture of foot, except ankle
0.809 0.191 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.809 0.191 0.000
Y40 Systemic antibiotics
0.809 0.191 0.000
F41 Other anxiety disorders
0.808 0.192 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.806 0.194 0.000
D03 Melanoma in situ
0.806 0.194 0.000
D04 Carcinoma in situ of skin
0.805 0.195 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.805 0.195 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.802 0.198 0.000
R26.3 Immobility
0.800 0.200 0.000
J18 Pneumonia, organism unspecified
0.799 0.201 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.797 0.203 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.796 0.204 0.000
D06 Carcinoma in situ of cervix uteri
0.794 0.206 0.000
D64 Other anaemias
0.793 0.207 0.000
Y45.0 Opioids and related analgesics
0.793 0.207 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.791 0.208 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.790 0.210 0.000
F43 Reaction to severe stress, and adjustment disorders
0.788 0.212 0.000
R25 Abnormal involuntary movements
0.787 0.213 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.786 0.214 0.000
M35 Other systemic involvement of connective tissue
0.786 0.214 0.000
Z72.0 Tobacco use
0.786 0.214 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.784 0.216 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.784 0.216 0.000
M86-M90 Other osteopathies
0.783 0.216 0.000
M34 Systemic sclerosis
0.781 0.219 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.781 0.219 0.000
D64.9 Anaemia, unspecified
0.781 0.219 0.000
S81 Open wound of lower leg
0.780 0.220 0.000
C67 Malignant neoplasm of bladder
0.779 0.221 0.000
T39.0 Salicylates
0.779 0.221 0.000
I12 Hypertensive renal disease
0.778 0.222 0.000
R10.2 Pelvic and perineal pain
0.777 0.223 0.000
F60 Specific personality disorders
0.776 0.224 0.000
M48 Other spondylopathies
0.775 0.225 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.774 0.226 0.000
T79-T79 Certain early complications of trauma
0.774 0.226 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.774 0.226 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.773 0.227 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.772 0.228 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.771 0.229 0.000
Z13.1 Special screening examination for diabetes mellitus
0.770 0.230 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.770 0.230 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.769 0.231 0.000
M40-M43 Deforming dorsopathies
0.768 0.232 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.768 0.232 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.767 0.233 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.767 0.233 0.000
R13 Dysphagia
0.767 0.233 0.000
C77.4 Inguinal and lower limb lymph nodes
0.764 0.235 0.000
F80-F89 Disorders of psychological development
0.763 0.237 0.000
L43 Lichen planus
0.763 0.237 0.000
J18.1 Lobar pneumonia, unspecified
0.762 0.238 0.000
V40-V49 Car occupant injured in transport accident
0.762 0.238 0.000
E07 Other disorders of thyroid
0.760 0.240 0.000
M60-M63 Disorders of muscles
0.759 0.241 0.000
E06 Thyroiditis
0.756 0.244 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.756 0.244 0.000
C66 Malignant neoplasm of ureter
0.756 0.244 0.000
M25.4 Effusion of joint
0.755 0.245 0.000
E61 Deficiency of other nutrient elements
0.755 0.245 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.753 0.247 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.753 0.247 0.000
H02 Other disorders of eyelid
0.752 0.248 0.000
S80 Superficial injury of lower leg
0.752 0.248 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.751 0.249 0.000
M91-M94 Chondropathies
0.750 0.250 0.000
M10 Gout
0.750 0.250 0.000
R47.8 Other and unspecified speech disturbances
0.748 0.252 0.000
Z74.0 Reduced mobility
0.748 0.252 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.747 0.252 0.000
R49 Voice disturbances
0.746 0.254 0.000
S32 Fracture of lumbar spine and pelvis
0.743 0.257 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.743 0.257 0.000
V20-V29 Motorcycle rider injured in transport accident
0.742 0.258 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.742 0.258 0.000
M07 Psoriatic and enteropathic arthropathies
0.740 0.260 0.000
S02 Fracture of skull and facial bones
0.738 0.262 0.000
T90 Sequelae of injuries of head
0.737 0.262 0.000
Y43.4 Immunosuppressive agents
0.737 0.263 0.000
C65 Malignant neoplasm of renal pelvis
0.737 0.263 0.000
I11 Hypertensive heart disease
0.735 0.265 0.000
R06 Abnormalities of breathing
0.732 0.268 0.000
M00-M03 Infectious arthropathies
0.731 0.269 0.000
L27 Dermatitis due to substances taken internally
0.731 0.269 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.730 0.269 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.730 0.270 0.000
V80-V89 Other land transport accidents
0.730 0.270 0.000
X60-X84 Intentional self-harm
0.730 0.270 0.000
R26.0 Ataxic gait
0.730 0.270 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.728 0.272 0.000
Y45.1 Salicylates
0.727 0.273 0.000
M23.5 Chronic instability of knee
0.727 0.273 0.000
Z04.5 Examination and observation following other inflicted injury
0.726 0.274 0.000
F40 Phobic anxiety disorders
0.726 0.274 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.726 0.274 0.000
C61 Malignant neoplasm of prostate
0.725 0.275 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.725 0.275 0.000
C51-C58 Malignant neoplasms of female genital organs
0.725 0.275 0.000
I73 Other peripheral vascular diseases
0.724 0.276 0.000
I12.0 Hypertensive renal disease with renal failure
0.724 0.276 0.000
X50-X57 Overexertion, travel and privation
0.723 0.277 0.000
E20 Hypoparathyroidism
0.723 0.277 0.000
H02.9 Disorder of eyelid, unspecified
0.723 0.277 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.721 0.279 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.720 0.280 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.719 0.281 0.000
S20-S29 Injuries to the thorax
0.719 0.281 0.000
F31 Bipolar affective disorder
0.719 0.281 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.718 0.282 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.717 0.282 0.000
S06 Intracranial injury
0.718 0.282 0.000
M24.0 Loose body in joint
0.717 0.283 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F38 Other mood [affective] disorders
0.717 0.283 0.000
F34 Persistent mood [affective] disorders
0.717 0.283 0.000
F30 Manic episode
0.717 0.283 0.000
F39 Unspecified mood [affective] disorder
0.717 0.283 0.000
E40-E46 Malnutrition
0.716 0.283 0.000
F32.8 Other depressive episodes
0.716 0.283 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
T36 Poisoning by systemic antibiotics
0.716 0.284 0.000
T93 Sequelae of injuries of lower limb
0.716 0.284 0.000
I24 Other acute ischaemic heart diseases
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.714 0.286 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.714 0.286 0.000
I21 Acute myocardial infarction
0.713 0.287 0.000
F41.9 Anxiety disorder, unspecified
0.713 0.287 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.712 0.288 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.712 0.288 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.712 0.288 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.712 0.288 0.000
E00 Congenital iodine-deficiency syndrome
0.712 0.288 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.712 0.288 0.000
M21 Other acquired deformities of limbs
0.711 0.289 0.000
Z10 Routine general health check-up of defined subpopulation
0.709 0.291 0.000
M05 Seropositive rheumatoid arthritis
0.707 0.293 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.707 0.293 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.707 0.293 0.000
M33 Dermatopolymyositis
0.707 0.293 0.000
M32 Systemic lupus erythematosus
0.707 0.293 0.000
M30 Polyarteritis nodosa and related conditions
0.707 0.293 0.000
I20.1 Angina pectoris with documented spasm
0.706 0.294 0.000
M65-M68 Disorders of synovium and tendon
0.705 0.295 0.000
L40.9 Psoriasis, unspecified
0.705 0.295 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.704 0.295 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.704 0.296 0.000
T39.4 Antirheumatics, not elsewhere classified
0.704 0.296 0.000
T39.2 Pyrazolone derivatives
0.704 0.296 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.704 0.296 0.000
C34 Malignant neoplasm of bronchus and lung
0.704 0.296 0.000
J18.9 Pneumonia, unspecified
0.704 0.296 0.000
M46 Other inflammatory spondylopathies
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
Y00-Y09 Assault
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
W50-W64 Exposure to animate mechanical forces
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
T92 Sequelae of injuries of upper limb
0.702 0.298 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.702 0.298 0.000
L73 Other follicular disorders
0.702 0.298 0.000
Y59 Other and unspecified vaccines and biological substances
0.701 0.299 0.000
Y58 Bacterial vaccines
0.701 0.299 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.701 0.299 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.701 0.299 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.701 0.299 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.701 0.299 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.701 0.299 0.000
Y48 Anaesthetics and therapeutic gases
0.701 0.299 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.701 0.299 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.701 0.299 0.000
Z00.5 Examination of potential donor of organ and tissue
0.701 0.299 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.701 0.299 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.701 0.299 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.700 0.300 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.700 0.300 0.000
Z13.5 Special screening examination for eye and ear disorders
0.700 0.300 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.700 0.300 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.700 0.300 0.000
Z13.2 Special screening examination for nutritional disorders
0.700 0.300 0.000
L72.0 Epidermal cyst
0.700 0.300 0.000
S92.3 Fracture of metatarsal bone
0.700 0.300 0.000
D06.9 Cervix, unspecified
0.699 0.301 0.000
C91 Lymphoid leukaemia
0.699 0.301 0.000
R82 Other abnormal findings in urine
0.698 0.302 0.000
Y43.9 Primarily systemic agent, unspecified
0.696 0.304 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.696 0.304 0.000
Y43.6 Enzymes, not elsewhere classified
0.696 0.304 0.000
Y43.5 Acidifying and alkalising agents
0.696 0.304 0.000
Y43.2 Antineoplastic natural products
0.696 0.304 0.000
Y43.1 Antineoplastic antimetabolites
0.696 0.304 0.000
Y43.0 Antiallergic and antiemetic drugs
0.696 0.304 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.696 0.304 0.000
R47.0 Dysphasia and aphasia
0.696 0.304 0.000
Chapter XXII Codes for special purposes
0.696 0.304 0.000
S50-S59 Injuries to the elbow and forearm
0.695 0.305 0.000
T46.1 Calcium-channel blockers
0.695 0.305 0.000
S14 Injury of nerves and spinal cord at neck level
0.695 0.305 0.000
Y44 Agents primarily affecting blood constituents
0.695 0.305 0.000
T43.6 Psychostimulants with abuse potential
0.694 0.306 0.000
M70-M79 Other soft tissue disorders
0.694 0.306 0.000
Z00.6 Examination for normal comparison and control in clinical research programme
0.694 0.306 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.693 0.307 0.000
M48.0 Spinal stenosis
0.693 0.307 0.000
R19.5 Other fecal abnormalities
0.693 0.307 0.000
Z73.3 Stress, not elsewhere classified
0.692 0.308 0.000
E04.8 Other specified non-toxic goitre
0.692 0.308 0.000
E04.0 Non-toxic diffuse goitre
0.692 0.308 0.000
F99-F99 Unspecified mental disorder
0.692 0.308 0.000
C77.2 Intra-abdominal lymph nodes
0.692 0.308 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.691 0.309 0.000
E24 Cushing's syndrome
0.691 0.309 0.000
E67 Other hyperalimentation
0.691 0.309 0.000
E68 Sequelae of hyperalimentation
0.691 0.309 0.000
E65 Localised adiposity
0.691 0.309 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.690 0.309 0.000
E61.1 Iron deficiency
0.690 0.310 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.689 0.310 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.689 0.311 0.000
M25.9 Joint disorder, unspecified
0.689 0.311 0.000
M23.4 Loose body in knee
0.689 0.311 0.000
L10-L14 Bullous disorders
0.689 0.311 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.688 0.312 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.688 0.312 0.000
L40.0 Psoriasis vulgaris
0.687 0.313 0.000
F60.9 Personality disorder, unspecified
0.687 0.313 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.687 0.313 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.686 0.314 0.000
M47 Spondylosis
0.684 0.316 0.000
E27 Other disorders of adrenal gland
0.683 0.317 0.000
I00-I02 Acute rheumatic fever
0.683 0.317 0.000
S80.9 Superficial injury of lower leg, unspecified
0.682 0.318 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.682 0.318 0.000
I30-I52 Other forms of heart disease
0.681 0.319 0.000
H25-H28 Disorders of lens
0.681 0.319 0.000
S40-S49 Injuries to the shoulder and upper arm
0.680 0.319 0.000
I70 Atherosclerosis
0.680 0.320 0.000
M85 Other disorders of bone density and structure
0.679 0.320 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.679 0.321 0.000
Z76 Persons encountering health services in other circumstances
0.679 0.321 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.679 0.321 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.679 0.321 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.678 0.322 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.678 0.322 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.678 0.322 0.000
T66-T78 Other and unspecified effects of external causes
0.677 0.323 0.000
S99 Other and unspecified injuries of ankle and foot
0.676 0.324 0.000
M14 Arthropathies in other diseases classified elsewhere
0.676 0.324 0.000
M12 Other specific arthropathies
0.676 0.324 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.676 0.324 0.000
M08 Juvenile arthritis
0.676 0.324 0.000
C62 Malignant neoplasm of testis
0.676 0.324 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.676 0.324 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.676 0.324 0.000
R25.2 Cramp and spasm
0.674 0.326 0.000
H50 Other strabismus
0.673 0.327 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.673 0.327 0.000
C67.4 Posterior wall of bladder
0.673 0.327 0.000
M48.06 Spinal stenosis (Lumbar region)
0.673 0.327 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.672 0.328 0.000
E66.1 Drug-induced obesity
0.672 0.328 0.000
E66.0 Obesity due to excess calories
0.672 0.328 0.000
E22 Hyperfunction of pituitary gland
0.672 0.328 0.000
M84 Disorders of continuity of bone
0.672 0.328 0.000
R40 Somnolence, stupor and coma
0.672 0.328 0.000
E21.3 Hyperparathyroidism, unspecified
0.672 0.328 0.000
M22 Disorders of patella
0.672 0.328 0.000
T98 Sequelae of other and unspecified effects of external causes
0.672 0.328 0.000
T95 Sequelae of burns, corrosions and frostbite
0.672 0.328 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.672 0.328 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.672 0.328 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.672 0.328 0.000
H04 Disorders of lachrymal system
0.672 0.328 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.672 0.328 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.672 0.328 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.672 0.328 0.000
T42.3 Barbiturates
0.672 0.328 0.000
T42.2 Succinimides and oxazolidinediones
0.672 0.328 0.000
T42.1 Iminostilbenes
0.672 0.328 0.000
T42.0 Hydantoin derivatives
0.672 0.328 0.000
M31 Other necrotising vasculopathies
0.671 0.329 0.000
L60.8 Other nail disorders
0.670 0.330 0.000
Z00.0 General medical examination
0.670 0.330 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.670 0.330 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.670 0.330 0.000
R06.5 Mouth breathing
0.670 0.330 0.000
S02.2 Fracture of nasal bones
0.670 0.330 0.000
R47.1 Dysarthria and anarthria
0.669 0.330 0.000
D62 Acute posthaemorrhagic anaemia
0.669 0.331 0.000
E03.8 Other specified hypothyroidism
0.669 0.331 0.000
E03.5 Myxoedema coma
0.669 0.331 0.000
E03.4 Atrophy of thyroid (acquired)
0.669 0.331 0.000
E03.3 Postinfectious hypothyroidism
0.669 0.331 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.669 0.331 0.000
E03.1 Congenital hypothyroidism without goitre
0.669 0.331 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.669 0.331 0.000
S81.0 Open wound of knee
0.669 0.331 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.669 0.331 0.000
M20 Acquired deformities of fingers and toes
0.668 0.332 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.667 0.333 0.000
L40.5 Arthropathic psoriasis
0.667 0.333 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.666 0.334 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.665 0.334 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.665 0.335 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.665 0.335 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.665 0.335 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.665 0.335 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.665 0.335 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.665 0.335 0.000
F48 Other neurotic disorders
0.665 0.335 0.000
F44 Dissociative [conversion] disorders
0.665 0.335 0.000
F42 Obsessive-compulsive disorder
0.665 0.335 0.000
O36 Maternal care for other known or suspected foetal problems
0.665 0.335 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.664 0.336 0.000
E28 Ovarian dysfunction
0.663 0.336 0.000
T91.1 Sequelae of fracture of spine
0.663 0.336 0.000
E55 Vitamin D deficiency
0.662 0.337 0.000
C32 Malignant neoplasm of larynx
0.662 0.338 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.662 0.338 0.000
L43.9 Lichen planus, unspecified
0.662 0.338 0.000
I22 Subsequent myocardial infarction
0.662 0.338 0.000
E66.8 Other obesity
0.661 0.339 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.661 0.339 0.000
L75 Apocrine sweat disorders
0.660 0.339 0.000
L74 Eccrine sweat disorders
0.660 0.339 0.000
L70 Acne
0.660 0.339 0.000
L68 Hypertrichosis
0.660 0.339 0.000
L67 Hair colour and hair shaft abnormalities
0.660 0.339 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.660 0.339 0.000
L65 Other nonscarring hair loss
0.660 0.339 0.000
L64 Androgenic alopecia
0.660 0.339 0.000
L63 Alopecia areata
0.660 0.339 0.000
L62 Nail disorders in diseases classified elsewhere
0.660 0.339 0.000
Y45.2 Propionic acid derivatives
0.660 0.340 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.660 0.340 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.660 0.340 0.000
D55-D59 Haemolytic anaemias
0.659 0.341 0.000
M23.9 Internal derangement of knee, unspecified
0.659 0.341 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.659 0.341 0.000
M23.1 Discoid meniscus (congenital)
0.659 0.341 0.000
M23.0 Cystic meniscus
0.659 0.341 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.658 0.341 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.657 0.342 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.657 0.342 0.000
R90.0 Intracranial space-occupying lesion
0.657 0.343 0.000
I23 Certain current complications following acute myocardial infarction
0.657 0.343 0.000
Z12 Special screening examination for neoplasms
0.657 0.343 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.656 0.344 0.000
R40.0 Somnolence
0.656 0.344 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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