TreeWAS – Variant ID: rs17826816

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11 Non-insulin-dependent diabetes mellitus	0.000	0.139	0.861
E10-E14 Diabetes mellitus	0.000	0.145	0.855
E14 Unspecified diabetes mellitus	0.000	0.150	0.850
E14.3 With ophthalmic complications	0.000	0.158	0.842
E11.3 With ophthalmic complications	0.000	0.167	0.833
E11.4 With neurological complications	0.000	0.188	0.812
E13 Other specified diabetes mellitus	0.000	0.234	0.766
E11.8 With unspecified complications	0.000	0.252	0.748
E11.6 With other specified complications	0.000	0.260	0.740
E11.2 With renal complications	0.000	0.266	0.734
E11.1 With ketoacidosis	0.000	0.279	0.721
E10 Insulin-dependent diabetes mellitus	0.000	0.281	0.719
E13.9 Without complications	0.000	0.290	0.710
E14.9 Without complications	0.000	0.306	0.694
E10.2 With renal complications	0.000	0.321	0.679
E14.6 With other specified complications	0.000	0.323	0.677
E14.8 With unspecified complications	0.000	0.336	0.664
E14.4 With neurological complications	0.000	0.338	0.662
E11.5 With peripheral circulatory complications	0.000	0.357	0.643
E10.5 With peripheral circulatory complications	0.000	0.366	0.634
E14.1 With ketoacidosis	0.000	0.369	0.631
E11.7 With multiple complications	0.000	0.382	0.618
E12 Malnutrition-related diabetes mellitus	0.000	0.387	0.613
E14.7 With multiple complications	0.000	0.391	0.609
E14.0 With coma	0.000	0.391	0.609
E10.6 With other specified complications	0.000	0.394	0.606
E11.0 With coma	0.000	0.447	0.553
E10.3 With ophthalmic complications	0.000	0.448	0.552
E13.8 With unspecified complications	0.000	0.451	0.549
E13.7 With multiple complications	0.000	0.451	0.549
E13.6 With other specified complications	0.000	0.451	0.549
E13.5 With peripheral circulatory complications	0.000	0.451	0.549
E13.4 With neurological complications	0.000	0.451	0.549
E13.2 With renal complications	0.000	0.451	0.549
E13.1 With ketoacidosis	0.000	0.451	0.549
E13.0 With coma	0.000	0.451	0.549
E13.3 With ophthalmic complications	0.000	0.480	0.519
E10.7 With multiple complications	0.000	0.484	0.516
E10.8 With unspecified complications	0.000	0.488	0.512
E11.9 Without complications	0.000	0.503	0.497
E14.2 Withrenal complications	0.000	0.505	0.495
E14.5 With peripheral circulatory complications	0.000	0.506	0.494
E12.9 Without complications	0.000	0.560	0.440
E12.8 With unspecified complications	0.000	0.560	0.440
E12.7 With multiple complications	0.000	0.560	0.440
E12.6 With other specified complications	0.000	0.560	0.440
E12.5 With peripheral circulatory complications	0.000	0.560	0.440
E12.4 With neurological complications	0.000	0.560	0.440
E12.3 With ophthalmic complications	0.000	0.560	0.440
E12.2 With renal complications	0.000	0.560	0.440
E12.1 With ketoacidosis	0.000	0.560	0.440
E12.0 With coma	0.000	0.560	0.440
E10.0 With coma	0.000	0.563	0.437
E10.4 With neurological complications	0.000	0.582	0.418
E10.1 With ketoacidosis	0.000	0.654	0.346
K70.3 Alcoholic cirrhosis of liver	0.000	0.657	0.343
K70 Alcoholic liver disease	0.000	0.657	0.343
K70.4 Alcoholic hepatic failure	0.000	0.670	0.330
K70.9 Alcoholic liver disease, unspecified	0.000	0.676	0.324
K70.0 Alcoholic fatty liver	0.000	0.689	0.311
K70.1 Alcoholic hepatitis	0.000	0.728	0.272
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.781	0.219
G90-G99 Other disorders of the nervous system	0.000	0.885	0.115
G93 Other disorders of brain	0.000	0.886	0.114
G95 Other diseases of spinal cord	0.000	0.888	0.112
G93.6 Cerebral oedema	0.000	0.891	0.109
G93.4 Encephalopathy, unspecified	0.000	0.892	0.108
G93.0 Cerebral cysts	0.000	0.894	0.106
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.896	0.104
G95.8 Other specified diseases of spinal cord	0.000	0.898	0.102
G95.1 Vascular myelopathies	0.000	0.900	0.100
G91 Hydrocephalus	0.000	0.900	0.100
G96 Other disorders of central nervous system	0.000	0.901	0.099
G90 Disorders of autonomic nervous system	0.000	0.906	0.094
G97.8 Other postprocedural disorders of nervous system	0.000	0.906	0.094
G95.9 Disease of spinal cord, unspecified	0.000	0.908	0.092
G91.2 Normal-pressure hydrocephalus	0.000	0.910	0.090
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.911	0.089
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.911	0.089
G95.2 Cord compression, unspecified	0.000	0.917	0.083
G92 Toxic encephalopathy	0.000	0.918	0.082
G91.8 Other hydrocephalus	0.000	0.918	0.082
G93.7 Reye's syndrome	0.000	0.918	0.082
G93.8 Other specified disorders of brain	0.000	0.918	0.082
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.919	0.081
G90.3 Multisystem degeneration	0.000	0.921	0.079
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.923	0.077
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.924	0.076
G93.2 Benign intracranial hypertension	0.000	0.925	0.075
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.925	0.075
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.925	0.075
G95.0 Syringomyelia and syringobulbia	0.000	0.925	0.074
G96.8 Other specified disorders of central nervous system	0.000	0.926	0.074
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.928	0.072
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.928	0.071
G96.9 Disorder of central nervous system, unspecified	0.000	0.929	0.071
G93.5 Compression of brain	0.000	0.929	0.071
G91.0 Communicating hydrocephalus	0.000	0.931	0.069
G93.9 Disorder of brain, unspecified	0.000	0.931	0.069
G93.3 Postviral fatigue syndrome	0.000	0.932	0.068
G90.4 Autonomic dysreflexia	0.000	0.932	0.068
G90.1 Familial dysautonomia [Riley-Day]	0.000	0.932	0.068
G96.0 Cerebrospinal fluid leak	0.000	0.933	0.067
G94.2 Hydrocephalus in other diseases classified elsewhere	0.000	0.933	0.067
G91.9 Hydrocephalus, unspecified	0.000	0.933	0.067
G91.1 Obstructive hydrocephalus	0.000	0.935	0.065
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.939	0.061
G90.2 Horner's syndrome	0.000	0.940	0.060
G90.8 Other disorders of autonomic nervous system	0.000	0.940	0.060
E10.9 Without complications	0.000	0.940	0.060
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.941	0.059
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.000	0.942	0.058
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.000	0.942	0.058
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.948	0.051
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.000	0.955	0.045
G94.1 Hydrocephalus in neoplastic disease	0.000	0.958	0.042
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.000	0.958	0.042
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.000	0.958	0.042
K70-K77 Diseases of liver	0.000	0.965	0.035
E07.9 Disorder of thyroid, unspecified	0.000	0.967	0.033
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.969	0.031
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.969	0.031
K74 Fibrosis and cirrhosis of liver	0.000	0.971	0.029
E07 Other disorders of thyroid	0.000	0.971	0.029
E00-E07 Disorders of thyroid gland	0.000	0.972	0.028
K74.3 Primary biliary cirrhosis	0.000	0.973	0.027
K77 Liver disorders in diseases classified elsewhere	0.000	0.975	0.025
K76 Other diseases of liver	0.000	0.976	0.024
K74.0 Hepatic fibrosis	0.000	0.976	0.024
E04 Other non-toxic goitre	0.000	0.977	0.023
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.977	0.023
H02.4 Ptosis of eyelid	0.000	0.978	0.022
E04.2 Non-toxic multinodular goitre	0.000	0.978	0.022
K74.4 Secondary biliary cirrhosis	0.000	0.979	0.021
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.979	0.021
K74.1 Hepatic sclerosis	0.000	0.979	0.021
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.979	0.021
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.979	0.021
E07.1 Dyshormogenetic goitre	0.000	0.979	0.021
E07.0 Hypersecretion of calcitonin	0.000	0.979	0.021
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.980	0.020
E00 Congenital iodine-deficiency syndrome	0.000	0.980	0.020
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.980	0.020
K74.5 Biliary cirrhosis, unspecified	0.000	0.980	0.020
K73 Chronic hepatitis, not elsewhere classified	0.000	0.980	0.020
E40-E46 Malnutrition	0.000	0.980	0.020
E04.0 Non-toxic diffuse goitre	0.000	0.980	0.020
K75 Other inflammatory liver diseases	0.000	0.981	0.019
H02.9 Disorder of eyelid, unspecified	0.000	0.981	0.019
K76.7 Hepatorenal syndrome	0.000	0.981	0.019
K71 Toxic liver disease	0.000	0.981	0.018
H02 Other disorders of eyelid	0.000	0.982	0.018
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.982	0.018
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.982	0.018
K76.9 Liver disease, unspecified	0.000	0.983	0.017
H02.3 Blepharochalasis	0.000	0.983	0.017
K76.5 Hepatic veno-occlusive disease	0.000	0.983	0.017
K76.4 Peliosis hepatis	0.000	0.983	0.017
K76.3 Infarction of liver	0.000	0.983	0.017
K76.2 Central haemorrhagic necrosis of liver	0.000	0.983	0.017
H02.5 Other disorders affecting eyelid function	0.000	0.983	0.017
E04.8 Other specified non-toxic goitre	0.000	0.983	0.017
K76.1 Chronic passive congestion of liver	0.000	0.983	0.017
K76.6 Portal hypertension	0.000	0.983	0.017
E16 Other disorders of pancreatic internal secretion	0.000	0.983	0.017
E15 Nondiabetic hypoglycaemic coma	0.000	0.983	0.016
E05.9 Thyrotoxicosis, unspecified	0.000	0.984	0.016
E65-E68 Obesity and other hyperalimentation	0.000	0.984	0.016
K75.0 Abscess of liver	0.000	0.984	0.016
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.984	0.016
E05.5 Thyroid crisis or storm	0.000	0.985	0.015
E05.4 Thyrotoxicosis factitia	0.000	0.985	0.015
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.985	0.015
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.985	0.015
K74.6 Other and unspecified cirrhosis of liver	0.000	0.985	0.015
E05.8 Other thyrotoxicosis	0.000	0.985	0.015
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.985	0.015
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.985	0.015
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.985	0.015
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.985	0.015
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.985	0.015
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.985	0.015
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.985	0.015
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.985	0.015
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.985	0.015
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.985	0.015
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.985	0.014
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.985	0.014
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.985	0.014
E45 Retarded development following protein-energy malnutrition	0.000	0.985	0.014
E43 Unspecified severe protein-energy malnutrition	0.000	0.985	0.014
E42 Marasmic kwashiorkor	0.000	0.985	0.014
E41 Nutritional marasmus	0.000	0.985	0.014
E40 Kwashiorkor	0.000	0.985	0.014
H02.2 Lagophthalmos	0.000	0.985	0.014
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.986	0.014
E06 Thyroiditis	0.000	0.986	0.014
E16.2 Hypoglycaemia, unspecified	0.000	0.986	0.014
K75.2 Nonspecific reactive hepatitis	0.000	0.986	0.014
K75.1 Phlebitis of portal vein	0.000	0.986	0.014
K71.9 Toxic liver disease, unspecified	0.000	0.986	0.013
K71.8 Toxic liver disease with other disorders of liver	0.000	0.986	0.013
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.986	0.013
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.986	0.013
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.986	0.013
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.986	0.013
K71.2 Toxic liver disease with acute hepatitis	0.000	0.986	0.013
K71.0 Toxic liver disease with cholestasis	0.000	0.986	0.013
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.986	0.013
H02.7 Other degenerative disorders of eyelid and periocular area	0.000	0.987	0.013
E04.9 Non-toxic goitre, unspecified	0.000	0.987	0.013
K75.9 Inflammatory liver disease, unspecified	0.000	0.987	0.013
K73.9 Chronic hepatitis, unspecified	0.000	0.987	0.012
H02.1 Ectropion of eyelid	0.000	0.988	0.012
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.988	0.012
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.988	0.012
E16.4 Abnormal secretion of gastrin	0.000	0.988	0.012
E16.3 Increased secretion of glucagon	0.000	0.988	0.012
E16.1 Other hypoglycaemia	0.000	0.988	0.012
E46 Unspecified protein-energy malnutrition	0.000	0.988	0.012
E67 Other hyperalimentation	0.000	0.988	0.012
E68 Sequelae of hyperalimentation	0.000	0.988	0.012
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.988	0.011
E65 Localised adiposity	0.000	0.988	0.012
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.988	0.011
E07.8 Other specified disorders of thyroid	0.001	0.989	0.011
K75.4 Autoimmune hepatitis	0.000	0.989	0.011
H02.6 Xanthelasma of eyelid	0.000	0.989	0.011
E44.1 Mild protein-energy malnutrition	0.000	0.989	0.011
E44.0 Moderate protein-energy malnutrition	0.000	0.989	0.011
D86.0 Sarcoidosis of lung	0.011	0.989	0.000
E06.4 Drug-induced thyroiditis	0.000	0.989	0.010
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.989	0.010
E06.1 Subacute thyroiditis	0.000	0.989	0.010
E06.0 Acute thyroiditis	0.000	0.989	0.010
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.001	0.989	0.010
E04.1 Non-toxic single thyroid nodule	0.000	0.989	0.010
E06.5 Other chronic thyroiditis	0.000	0.990	0.010
K72 Hepatic failure, not elsewhere classified	0.001	0.990	0.009
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.990	0.010
D86 Sarcoidosis	0.010	0.990	0.000
D86.9 Sarcoidosis, unspecified	0.010	0.990	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.990	0.010
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.991	0.009
K75.8 Other specified inflammatory liver diseases	0.000	0.991	0.009
E67.8 Other specified hyperalimentation	0.000	0.991	0.009
E67.3 Hypervitaminosis D	0.000	0.991	0.009
E67.2 Megavitamin-B6 syndrome	0.000	0.991	0.009
E67.1 Hypercarotenaemia	0.000	0.991	0.009
E67.0 Hypervitaminosis A	0.000	0.991	0.009
E06.9 Thyroiditis, unspecified	0.000	0.991	0.008
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.008	0.992	0.000
D86.8 Sarcoidosis of other and combined sites	0.008	0.992	0.000
E50-E64 Other nutritional deficiencies	0.000	0.992	0.008
E06.3 Autoimmune thyroiditis	0.000	0.992	0.008
E23 Hypofunction and other disorders of pituitary gland	0.000	0.992	0.008
K72.1 Chronic hepatic failure	0.001	0.992	0.007
E03 Other hypothyroidism	0.000	0.992	0.008
Z11.2 Special screening examination for other bacterial diseases	0.000	0.992	0.008
E20-E35 Disorders of other endocrine glands	0.000	0.992	0.008
D86.3 Sarcoidosis of skin	0.007	0.993	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.000	0.993	0.007
S79.9 Unspecified injury of hip and thigh	0.000	0.993	0.007
D86.1 Sarcoidosis of lymph nodes	0.007	0.993	0.000
E23.0 Hypopituitarism	0.000	0.993	0.007
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.000	0.993	0.007
Z11.5 Special screening examination for other viral diseases	0.000	0.993	0.007
N85.4 Malposition of uterus	0.007	0.993	0.000
E23.2 Diabetes insipidus	0.000	0.993	0.007
J35.0 Chronic tonsillitis	0.000	0.993	0.007
E23.6 Other disorders of pituitary gland	0.000	0.994	0.006
E27 Other disorders of adrenal gland	0.000	0.994	0.006
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.000	0.994	0.006
H02.0 Entropion and trichiasis of eyelid	0.000	0.994	0.006
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.994	0.006
E63 Other nutritional deficiencies	0.000	0.994	0.006
E56 Other vitamin deficiencies	0.000	0.994	0.006
E50 Vitamin A deficiency	0.000	0.994	0.006
E60 Dietary zinc deficiency	0.000	0.994	0.006
E59 Dietary selenium deficiency	0.000	0.994	0.006
E58 Dietary calcium deficiency	0.000	0.994	0.006
E54 Ascorbic acid deficiency	0.000	0.994	0.006
E52 Niacin deficiency [pellagra]	0.000	0.994	0.006
E66 Obesity	0.000	0.994	0.006
E51 Thiamine deficiency	0.000	0.994	0.006
E23.7 Disorder of pituitary gland, unspecified	0.000	0.994	0.006
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.994	0.006
E23.1 Drug-induced hypopituitarism	0.000	0.994	0.006
E03.5 Myxoedema coma	0.000	0.994	0.006
E03.4 Atrophy of thyroid (acquired)	0.000	0.994	0.006
E03.3 Postinfectious hypothyroidism	0.000	0.994	0.006
E03.1 Congenital hypothyroidism without goitre	0.000	0.994	0.006
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.994	0.006
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.994	0.006
E32 Diseases of thymus	0.000	0.994	0.006
E31 Polyglandular dysfunction	0.000	0.994	0.006
E30 Disorders of puberty, not elsewhere classified	0.000	0.994	0.006
E27.8 Other specified disorders of adrenal gland	0.000	0.994	0.006
E03.8 Other specified hypothyroidism	0.000	0.994	0.006
Z11.1 Special screening examination for respiratory tuberculosis	0.000	0.994	0.006
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.994	0.006
E25 Adrenogenital disorders	0.000	0.994	0.005
C80.9 Malignant neoplasm, unspecified	0.006	0.994	0.000
Z11.8 Special screening examination for other infectious and parasitic diseases	0.000	0.995	0.005
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.000	0.995	0.005
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.000	0.995	0.005
E26 Hyperaldosteronism	0.000	0.995	0.005
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.995	0.005
E24 Cushing's syndrome	0.000	0.995	0.005
E27.1 Primary adrenocortical insufficiency	0.000	0.995	0.005
S79 Other and unspecified injuries of hip and thigh	0.000	0.995	0.005
E27.9 Disorder of adrenal gland, unspecified	0.000	0.995	0.005
E20 Hypoparathyroidism	0.000	0.995	0.005
R93 Abnormal findings on diagnostic imaging of other body structures	0.000	0.995	0.005
E27.5 Adrenomedullary hyperfunction	0.000	0.995	0.005
E27.0 Other adrenocortical overactivity	0.000	0.995	0.005
E66.0 Obesity due to excess calories	0.000	0.995	0.005
C45 Mesothelioma	0.005	0.995	0.000
E27.2 Addisonian crisis	0.000	0.995	0.005
E50.9 Vitamin A deficiency, unspecified	0.000	0.995	0.004
E50.8 Other manifestations of vitamin A deficiency	0.000	0.995	0.004
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.995	0.004
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.995	0.004
E50.5 Vitamin A deficiency with night blindness	0.000	0.995	0.004
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.995	0.004
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.995	0.004
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.995	0.004
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.995	0.004
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.995	0.004
E56.9 Vitamin deficiency, unspecified	0.000	0.995	0.004
E56.8 Deficiency of other vitamins	0.000	0.995	0.004
E56.1 Deficiency of vitamin K	0.000	0.995	0.004
E56.0 Deficiency of vitamin E	0.000	0.995	0.004
E63.9 Nutritional deficiency, unspecified	0.000	0.995	0.004
E63.8 Other specified nutritional deficiencies	0.000	0.995	0.004
E63.1 Imbalance of constituents of food intake	0.000	0.995	0.004
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.995	0.004
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.995	0.004
E64.8 Sequelae of other nutritional deficiencies	0.000	0.995	0.004
E64.3 Sequelae of rickets	0.000	0.995	0.004
E64.2 Sequelae of vitamin C deficiency	0.000	0.995	0.004
E64.1 Sequelae of vitamin A deficiency	0.000	0.995	0.004
E64.0 Sequelae of protein-energy malnutrition	0.000	0.995	0.004
S79.8 Other specified injuries of hip and thigh	0.000	0.995	0.005
E66.1 Drug-induced obesity	0.000	0.995	0.005
C45.0 Mesothelioma of pleura	0.005	0.995	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.995	0.005
E51.9 Thiamine deficiency, unspecified	0.000	0.995	0.004
E51.8 Other manifestations of thiamine deficiency	0.000	0.995	0.004
E51.1 Beriberi	0.000	0.995	0.004
E51.2 Wernicke's encephalopathy	0.000	0.996	0.004
J84.1 Other interstitial pulmonary diseases with fibrosis	0.004	0.996	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.000	0.996	0.004
E28 Ovarian dysfunction	0.000	0.996	0.004
C45.7 Mesothelioma of other sites	0.004	0.996	0.000
E30.9 Disorder of puberty, unspecified	0.000	0.996	0.004
E30.8 Other disorders of puberty	0.000	0.996	0.004
E30.1 Precocious puberty	0.000	0.996	0.004
E30.0 Delayed puberty	0.000	0.996	0.004
E31.9 Polyglandular dysfunction, unspecified	0.000	0.996	0.004
E31.8 Other polyglandular dysfunction	0.000	0.996	0.004
E31.1 Polyglandular hyperfunction	0.000	0.996	0.004
E31.0 Autoimmune polyglandular failure	0.000	0.996	0.004
E32.9 Disease of thymus, unspecified	0.000	0.996	0.004
E32.8 Other diseases of thymus	0.000	0.996	0.004
E32.1 Abscess of thymus	0.000	0.996	0.004
E32.0 Persistent hyperplasia of thymus	0.000	0.996	0.004
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.996	0.004
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.996	0.004
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.996	0.004
C49 Malignant neoplasm of other connective and soft tissue	0.004	0.996	0.000
K72.0 Acute and subacute hepatic failure	0.002	0.996	0.003
E34 Other endocrine disorders	0.000	0.996	0.004
E61 Deficiency of other nutrient elements	0.000	0.996	0.004
E29 Testicular dysfunction	0.000	0.996	0.004
E25.9 Adrenogenital disorder, unspecified	0.000	0.996	0.004
E25.8 Other adrenogenital disorders	0.000	0.996	0.004
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.996	0.004
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.004	0.996	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.996	0.004
H36.0 Diabetic retinopathy	0.000	0.996	0.004
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.004	0.996	0.000
C48.0 Retroperitoneum	0.004	0.996	0.000
E22 Hyperfunction of pituitary gland	0.000	0.996	0.004
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.996	0.004
C49.5 Connective and soft tissue of pelvis	0.004	0.996	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.996	0.004
E26.9 Hyperaldosteronism, unspecified	0.000	0.996	0.004
E26.8 Other hyperaldosteronism	0.000	0.996	0.004
E26.1 Secondary hyperaldosteronism	0.000	0.996	0.004
E55 Vitamin D deficiency	0.000	0.996	0.004
R93.6 Abnormal findings on diagnostic imaging of limbs	0.000	0.996	0.004
E24.8 Other Cushing's syndrome	0.000	0.996	0.004
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.996	0.004
E24.3 Ectopic ACTH syndrome	0.000	0.996	0.004
E24.1 Nelson's syndrome	0.000	0.996	0.004
N81.5 Vaginal enterocele	0.000	0.996	0.004
G56.8 Other mononeuropathies of upper limb	0.004	0.996	0.000
S79.7 Multiple injuries of hip and thigh	0.000	0.996	0.004
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.996	0.004
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.996	0.004
C45.9 Mesothelioma, unspecified	0.004	0.996	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.004	0.996	0.000
C49.9 Connective and soft tissue, unspecified	0.004	0.996	0.000
E20.8 Other hypoparathyroidism	0.000	0.996	0.004
E20.1 Pseudohypoparathyroidism	0.000	0.996	0.004
E20.0 Idiopathic hypoparathyroidism	0.000	0.996	0.004
C49.3 Connective and soft tissue of thorax	0.004	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.996	0.004
C45.2 Mesothelioma of pericardium	0.004	0.996	0.000
C45.1 Mesothelioma of peritoneum	0.004	0.996	0.000
E26.0 Primary hyperaldosteronism	0.000	0.996	0.004
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.996	0.004
C49.4 Connective and soft tissue of abdomen	0.004	0.996	0.000
D80-D89 Certain disorders involving the immune mechanism	0.004	0.996	0.000
I89.1 Lymphangitis	0.000	0.996	0.004
C49.1 Connective and soft tissue of upper limb, including shoulder	0.003	0.996	0.000
C48.2 Peritoneum, unspecified	0.003	0.996	0.000
K72.9 Hepatic failure, unspecified	0.001	0.996	0.002
M22.3 Other derangements of patella	0.003	0.996	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.997	0.003
E28.8 Other ovarian dysfunction	0.000	0.997	0.003
E28.1 Androgen excess	0.000	0.997	0.003
E28.0 Oestrogen excess	0.000	0.997	0.003
C49.8 Overlapping lesion of connective and soft tissue	0.003	0.997	0.000
E28.3 Primary ovarian failure	0.000	0.997	0.003
C49.0 Connective and soft tissue of head, face and neck	0.003	0.997	0.000
M79.0 Rheumatism, unspecified	0.000	0.997	0.003
E24.0 Pituitary-dependent Cushing's disease	0.000	0.997	0.003
E34.5 Androgen resistance syndrome	0.000	0.997	0.003
E34.4 Constitutional tall stature	0.000	0.997	0.003
E34.3 Short stature, not elsewhere classified	0.000	0.997	0.003
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.997	0.003
E34.1 Other hypersecretion of intestinal hormones	0.000	0.997	0.003
E61.9 Deficiency of nutrient element, unspecified	0.000	0.997	0.003
E61.8 Deficiency of other specified nutrient elements	0.000	0.997	0.003
E61.7 Deficiency of multiple nutrient elements	0.000	0.997	0.003
E61.6 Vanadium deficiency	0.000	0.997	0.003
E61.5 Molybdenum deficiency	0.000	0.997	0.003
E61.4 Chromium deficiency	0.000	0.997	0.003
E61.3 Manganese deficiency	0.000	0.997	0.003
E61.0 Copper deficiency	0.000	0.997	0.003
E29.9 Testicular dysfunction, unspecified	0.000	0.997	0.003
E29.8 Other testicular dysfunction	0.000	0.997	0.003
E29.0 Testicular hyperfunction	0.000	0.997	0.003
C48.1 Specified parts of peritoneum	0.003	0.997	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.003	0.997	0.000
C46 Kaposi's sarcoma	0.003	0.997	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.003	0.997	0.000
E34.0 Carcinoid syndrome	0.000	0.997	0.003
C49.6 Connective and soft tissue of trunk, unspecified	0.003	0.997	0.000
E53 Deficiency of other B group vitamins	0.000	0.997	0.003
C80 Malignant neoplasm without specification of site	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.997	0.003
N73.6 Female pelvic peritoneal adhesions	0.000	0.997	0.003
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.997	0.003
E22.8 Other hyperfunction of pituitary gland	0.000	0.997	0.003
E61.2 Magnesium deficiency	0.000	0.997	0.003
E55.0 Rickets, active	0.000	0.997	0.003
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.003
H20.0 Acute and subacute iridocyclitis	0.003	0.997	0.000
D84 Other immunodeficiencies	0.003	0.997	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.003	0.997	0.000
I46.9 Cardiac arrest, unspecified	0.000	0.997	0.003
M22.2 Patellofemoral disorders	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.003	0.997	0.000
M89.9 Disorder of bone, unspecified	0.003	0.997	0.000
M79.08 Rheumatism, unspecified (Other)	0.000	0.997	0.003
E20.9 Hypoparathyroidism, unspecified	0.000	0.997	0.003
S43.0 Dislocation of shoulder joint	0.003	0.997	0.000
G56.2 Lesion of ulnar nerve	0.003	0.997	0.000
A04 Other bacterial intestinal infections	0.000	0.997	0.003
D83 Common variable immunodeficiency	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.000	0.997	0.003
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.997	0.003
R13 Dysphagia	0.000	0.997	0.003
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.997	0.003
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.997	0.003
D81 Combined immunodeficiencies	0.003	0.997	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.003	0.997	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.003	0.997	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
G24.5 Blepharospasm	0.000	0.997	0.003
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
M79.07 Rheumatism, unspecified (Ankle and foot)	0.000	0.997	0.003
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M79.04 Rheumatism, unspecified (Hand)	0.000	0.997	0.003
M79.03 Rheumatism, unspecified (Forearm)	0.000	0.997	0.003
M79.02 Rheumatism, unspecified (Upper arm)	0.000	0.997	0.003
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.003	0.997	0.000
C46.9 Kaposi's sarcoma, unspecified	0.002	0.997	0.000
C46.8 Kaposi's sarcoma of multiple organs	0.002	0.997	0.000
C46.7 Kaposi's sarcoma of other sites	0.002	0.997	0.000
C46.3 Kaposi's sarcoma of lymph nodes	0.002	0.997	0.000
C46.2 Kaposi's sarcoma of palate	0.002	0.997	0.000
C46.1 Kaposi's sarcoma of soft tissue	0.002	0.997	0.000
C46.0 Kaposi's sarcoma of skin	0.002	0.997	0.000
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.002	0.997	0.000
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations