TreeWAS – Variant ID: rs1799782

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIV Diseases of the genitourinary system	1.000	0.000
# Top node	1.000	0.000
N18 Chronic renal failure	1.000	0.000
N17-N19 Renal failure	1.000	0.000
N10-N16 Renal tubulo-interstitial diseases	1.000	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
N18.9 Chronic renal failure, unspecified	0.999	0.001
N13 Obstructive and reflux uropathy	0.998	0.002
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.997	0.003
Chapter XX External causes of morbidity and mortality	0.997	0.003
T84.0 Mechanical complication of internal joint prosthesis	0.994	0.006
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.993	0.007
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.993	0.007
Chapter VII Diseases of the eye and adnexa	0.991	0.009
N00-N08 Glomerular diseases	0.986	0.014
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.982	0.018
N13.3 Other and unspecified hydronephrosis	0.976	0.024
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.974	0.026
N70-N77 Inflammatory diseases of female pelvic organs	0.967	0.033
M05-M14 Inflammatory polyarthropathies	0.966	0.034
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.962	0.038
N18.0 End-stage renal disease	0.960	0.040
Y40 Systemic antibiotics	0.959	0.041
N25-N29 Other disorders of kidney and ureter	0.957	0.043
M06 Other rheumatoid arthritis	0.957	0.043
N05 Unspecified nephritic syndrome	0.951	0.049
T81 Complications of procedures, not elsewhere classified	0.947	0.053
H53-H54 Visual disturbances and blindness	0.947	0.053
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.946	0.054
T84.1 Mechanical complication of internal fixation device of bones of limb	0.946	0.054
N18.4 Chronic kidney disease, stage 4	0.944	0.056
M06.9 Rheumatoid arthritis, unspecified	0.943	0.057
S60-S69 Injuries to the wrist and hand	0.939	0.061
H50 Other strabismus	0.931	0.069
N13.4 Hydroureter	0.927	0.073
T81.8 Other complications of procedures, not elsewhere classified	0.926	0.074
N11 Chronic tubulo-interstitial nephritis	0.926	0.074
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.926	0.074
H02 Other disorders of eyelid	0.922	0.078
N03 Chronic nephritic syndrome	0.922	0.078
Q60-Q64 Congenital malformations of the urinary system	0.915	0.085
H50.1 Divergent concomitant strabismus	0.915	0.085
M86-M90 Other osteopathies	0.910	0.090
Y40.9 Systemic antibiotic, unspecified	0.909	0.091
Chapter VIII Diseases of the ear and mastoid process	0.906	0.094
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.905	0.095
M05 Seropositive rheumatoid arthritis	0.904	0.096
N28 Other disorders of kidney and ureter, not elsewhere classified	0.899	0.101
M70-M79 Other soft tissue disorders	0.897	0.103
H02.9 Disorder of eyelid, unspecified	0.895	0.105
H02.3 Blepharochalasis	0.893	0.107
N13.9 Obstructive and reflux uropathy, unspecified	0.892	0.108
N72 Inflammatory disease of cervix uteri	0.890	0.110
H54 Blindness and low vision	0.888	0.112
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.882	0.117
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.882	0.117
N28.8 Other specified disorders of kidney and ureter	0.882	0.118
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.880	0.120
N03.9 Unspecified	0.877	0.123
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.872	0.128
Y44 Agents primarily affecting blood constituents	0.869	0.131
S66 Injury of muscle and tendon at wrist and hand level	0.863	0.137
Y41 Other systemic anti-infectives and antiparasitics	0.862	0.137
Q50-Q56 Congenital malformations of genital organs	0.862	0.138
M05.9 Seropositive rheumatoid arthritis, unspecified	0.861	0.139
H90-H95 Other disorders of ear	0.859	0.141
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.853	0.147
N73 Other female pelvic inflammatory diseases	0.847	0.153
M89 Other disorders of bone	0.847	0.153
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.846	0.154
Chapter XXII Codes for special purposes	0.843	0.157
H93 Other disorders of ear, not elsewhere classified	0.843	0.157
N18.5 Chronic kidney disease, stage 5	0.842	0.158
N05.9 Unspecified	0.841	0.159
Q38-Q45 Other congenital malformations of the digestive system	0.839	0.161
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.839	0.161
N76 Other inflammation of vagina and vulva	0.837	0.163
H93.1 Tinnitus	0.831	0.169
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.831	0.169
N18.8 Other chronic renal failure	0.831	0.169
Q61 Cystic kidney disease	0.829	0.171
T82.4 Mechanical complication of vascular dialysis catheter	0.826	0.174
M79 Other soft tissue disorders, not elsewhere classified	0.823	0.177
S20-S29 Injuries to the thorax	0.823	0.177
N26 Unspecified contracted kidney	0.821	0.179
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.819	0.181
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.817	0.183
S64 Injury of nerves at wrist and hand level	0.815	0.185
M06.3 Rheumatoid nodule	0.812	0.188
H46-H48 Disorders of optic nerve and visual pathways	0.808	0.192
H49 Paralytic strabismus	0.805	0.195
Y46 Antiepileptics and anti-Parkinsonism drugs	0.803	0.197
H53 Visual disturbances	0.803	0.197
Y40.8 Other systemic antibiotics	0.801	0.199
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.801	0.199
Y57 Other and unspecified drugs and medicaments	0.800	0.200
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.798	0.202
H18 Other disorders of cornea	0.797	0.203
H54.0 Blindness, both eyes	0.797	0.203
N05.8 Other	0.797	0.203
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.796	0.204
T81.7 Vascular complications following a procedure, not elsewhere classified	0.795	0.205
T88 Other complications of surgical and medical care, not elsewhere classified	0.794	0.206
W50-W64 Exposure to animate mechanical forces	0.793	0.207
Y48 Anaesthetics and therapeutic gases	0.792	0.208
Y49 Psychotropic drugs, not elsewhere classified	0.791	0.208
H02.1 Ectropion of eyelid	0.790	0.210
T84.3 Mechanical complication of other bone devices, implants and grafts	0.789	0.211
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.787	0.213
V80-V89 Other land transport accidents	0.785	0.215
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.784	0.216
N13.6 Pyonephrosis	0.783	0.217
T20-T25 Burns and corrosions of external body surface, specified by site	0.783	0.217
N71 Inflammatory disease of uterus, except cervix	0.782	0.218
Y44.2 Anticoagulants	0.781	0.219
Y00-Y09 Assault	0.777	0.222
N08 Glomerular disorders in diseases classified elsewhere	0.777	0.223
V20-V29 Motorcycle rider injured in transport accident	0.776	0.224
Q60 Renal agenesis and other reduction defects of kidney	0.776	0.224
N05.2 Diffuse membranous glomerulonephritis	0.775	0.225
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.775	0.225
T85 Complications of other internal prosthetic devices, implants and grafts	0.773	0.227
T82.0 Mechanical complication of heart valve prosthesis	0.772	0.228
M79.1 Myalgia	0.771	0.229
H54.4 Blindness, one eye	0.770	0.230
W20-W49 Exposure to inanimate mechanical forces	0.769	0.231
V98-V99 Other and unspecified transport accidents	0.766	0.234
H53.2 Diplopia	0.766	0.234
T66-T78 Other and unspecified effects of external causes	0.762	0.238
N76.8 Other specified inflammation of vagina and vulva	0.762	0.238
S10-S19 Injuries to the neck	0.761	0.239
M75 Shoulder lesions	0.759	0.241
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.757	0.242
V40-V49 Car occupant injured in transport accident	0.757	0.243
M65-M68 Disorders of synovium and tendon	0.754	0.246
X10-X19 Contact with heat and hot substances	0.754	0.246
M79.6 Pain in limb	0.753	0.247
Y40.0 Penicillins	0.752	0.248
S62 Fracture at wrist and hand level	0.749	0.251
M06.98 Rheumatoid arthritis, unspecified (Other)	0.748	0.252
T80 Complications following infusion, transfusion and therapeutic injection	0.747	0.253
H60-H62 Diseases of external ear	0.746	0.254
M89.8 Other specified disorders of bone	0.746	0.254
N19 Unspecified renal failure	0.745	0.255
Q20-Q28 Congenital malformations of the circulatory system	0.743	0.256
X60-X84 Intentional self-harm	0.743	0.257
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.742	0.258
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.739	0.261
N11.1 Chronic obstructive pyelonephritis	0.739	0.261
N13.5 Kinking and stricture of ureter without hydronephrosis	0.738	0.262
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.737	0.262
Y43 Primarily systemic agents	0.737	0.263
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.737	0.263
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.737	0.263
T81.9 Unspecified complication of procedure	0.736	0.263
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.736	0.263
H50.2 Vertical strabismus	0.735	0.265
N73.9 Female pelvic inflammatory disease, unspecified	0.735	0.265
N70 Salpingitis and oophoritis	0.733	0.267
X58-X59 Accidental exposure to other and unspecified factors	0.732	0.268
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.732	0.268
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.730	0.269
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.730	0.270
Y60-Y69 Misadventures to patients during surgical and medical care	0.728	0.272
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.727	0.273
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.727	0.273
W00-W19 Falls	0.726	0.274
Q61.3 Polycystic kidney, unspecified	0.726	0.274
T87 Complications peculiar to reattachment and amputation	0.726	0.274
M60-M63 Disorders of muscles	0.725	0.275
H05 Disorders of orbit	0.724	0.276
H01 Other inflammation of eyelid	0.723	0.277
Q51 Congenital malformations of uterus and cervix	0.723	0.277
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.722	0.278
Q80-Q89 Other congenital malformations	0.722	0.278
M06.0 Seronegative rheumatoid arthritis	0.721	0.278
M76 Enthesopathies of lower limb, excluding foot	0.719	0.281
M87 Osteonecrosis	0.719	0.281
S64.1 Injury of median nerve at wrist and hand level	0.718	0.282
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.717	0.283
M75.5 Bursitis of shoulder	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
N18.1 Chronic kidney disease, stage 1	0.717	0.283
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.717	0.283
N15 Other renal tubulo-interstitial diseases	0.717	0.283
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.717	0.283
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.716	0.284
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.716	0.284
N13.7 Vesicoureteral-reflux-associated uropathy	0.715	0.284
H02.6 Xanthelasma of eyelid	0.715	0.285
Y35-Y36 Legal intervention and operations of war	0.715	0.285
Y10-Y34 Event of undetermined intent	0.715	0.285
X85-X99 Assault	0.715	0.285
X30-X39 Exposure to forces of nature	0.715	0.285
X00-X09 Exposure to smoke, fire and flames	0.715	0.285
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.715	0.285
W75-W84 Other accidental threats to breathing	0.715	0.285
W65-W74 Accidental drowning and submersion	0.715	0.285
V95-V97 Air and space transport accidents	0.715	0.285
V90-V94 Water transport accidents	0.715	0.285
V70-V79 Bus occupant injured in transport accident	0.715	0.285
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.715	0.285
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.715	0.285
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.715	0.285
V01-V09 Pedestrian injured in transport accident	0.715	0.285
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.712	0.288
Q35-Q37 Cleft lip and cleft palate	0.712	0.288
Q30-Q34 Congenital malformations of the respiratory system	0.712	0.288
Y59 Other and unspecified vaccines and biological substances	0.712	0.288
Y58 Bacterial vaccines	0.712	0.288
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.712	0.288
Y53 Agents primarily affecting the gastro-intestinal system	0.712	0.288
Y50 Central nervous system stimulants, not elsewhere classified	0.712	0.288
Y47 Sedatives, hypnotics and antianxiety drugs	0.712	0.288
N99-N99 Other disorders of the genitourinary system	0.711	0.289
M00-M03 Infectious arthropathies	0.710	0.290
N04 Nephrotic syndrome	0.709	0.291
H54.7 Unspecified visual loss	0.708	0.292
N07 Hereditary nephropathy, not elsewhere classified	0.707	0.293
N06 Isolated proteinuria with specified morphological lesion	0.707	0.293
N01 Rapidly progressive nephritic syndrome	0.707	0.293
N00 Acute nephritic syndrome	0.707	0.293
M79.66 Pain in limb (Lower leg)	0.707	0.293
Y41.5 Antiviral drugs	0.706	0.294
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.706	0.294
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.706	0.294
M06.4 Inflammatory polyarthropathy	0.706	0.294
S60 Superficial injury of wrist and hand	0.705	0.295
T82.3 Mechanical complication of other vascular grafts	0.705	0.295
Q00-Q07 Congenital malformations of the nervous system	0.705	0.295
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.703	0.297
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.702	0.298
M14 Arthropathies in other diseases classified elsewhere	0.701	0.299
M86 Osteomyelitis	0.701	0.299
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.699	0.301
M89.9 Disorder of bone, unspecified	0.698	0.302
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.697	0.303
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.696	0.304
X20-X29 Contact with venomous animals and plants	0.695	0.304
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.695	0.305
Q43 Other congenital malformations of intestine	0.694	0.306
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.693	0.307
N76.1 Subacute and chronic vaginitis	0.693	0.307
M12 Other specific arthropathies	0.692	0.307
M09 Juvenile arthritis in diseases classified elsewhere	0.692	0.307
M08 Juvenile arthritis	0.692	0.307
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.690	0.310
T15-T19 Effects of foreign body entering through natural orifice	0.690	0.310
H51 Other disorders of binocular movement	0.690	0.310
H60 Otitis externa	0.689	0.311
T79-T79 Certain early complications of trauma	0.688	0.311
X40-X49 Accidental poisoning by and exposure to noxious substances	0.688	0.311
S21 Open wound of thorax	0.688	0.312
H18.8 Other specified disorders of cornea	0.688	0.312
Y40.7 Antifungal antibiotics, systemically used	0.688	0.312
Y40.6 Rifamycins	0.688	0.312
Y40.5 Aminoglycosides	0.688	0.312
Y40.4 Tetracyclines	0.688	0.312
Y40.2 Chloramphenicol group	0.688	0.312
Y40.1 Cefalosporins and other -lactam antibiotics	0.688	0.312
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.687	0.312
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.687	0.313
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.686	0.314
N27 Small kidney of unknown cause	0.686	0.314
M06.8 Other specified rheumatoid arthritis	0.686	0.314
M06.2 Rheumatoid bursitis	0.686	0.314
M06.1 Adult-onset Still's disease	0.686	0.314
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.685	0.314
Q12 Congenital lens malformations	0.684	0.315
S64.3 Injury of digital nerve of thumb	0.682	0.318
N05.7 Diffuse crescentic glomerulonephritis	0.682	0.318
N05.6 Dense deposit disease	0.682	0.318
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.682	0.318
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.682	0.318
N05.1 Focal and segmental glomerular lesions	0.682	0.318
N05.0 Minor glomerular abnormality	0.682	0.318
X50-X57 Overexertion, travel and privation	0.681	0.319
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.681	0.319
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.679	0.321
N10 Acute tubulo-interstitial nephritis	0.679	0.321
V10-V19 Pedal cyclist injured in transport accident	0.678	0.322
Q79.8 Other congenital malformations of musculoskeletal system	0.678	0.322
H03 Disorders of eyelid in diseases classified elsewhere	0.678	0.322
Q79.6 Ehlers-Danlos syndrome	0.678	0.322
M91-M94 Chondropathies	0.678	0.322
H90 Conductive and sensorineural hearing loss	0.677	0.323
Q60.0 Renal agenesis, unilateral	0.676	0.324
N28.0 Ischaemia and infarction of kidney	0.676	0.324
N25 Disorders resulting from impaired renal tubular function	0.676	0.324
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.675	0.325
S65 Injury of blood vessels at wrist and hand level	0.673	0.327
T88.4 Failed or difficult intubation	0.672	0.328
S27 Injury of other and unspecified intrathoracic organs	0.671	0.329
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.670	0.330
S66.8 Injury of other muscles and tendons at wrist and hand level	0.670	0.330
Q61.0 Congenital single renal cyst	0.670	0.330
H02.2 Lagophthalmos	0.670	0.330
M75.2 Bicipital tendinitis	0.668	0.332
H50.8 Other specified strabismus	0.667	0.333
H50.6 Mechanical strabismus	0.667	0.333
H50.5 Heterophoria	0.667	0.333
H50.4 Other and unspecified heterotropia	0.667	0.333
H50.3 Intermittent heterotropia	0.667	0.333
Y46.7 Anti-Parkinsonism drugs	0.667	0.333
M72 Fibroblastic disorders	0.666	0.334
N73.6 Female pelvic peritoneal adhesions	0.665	0.335
Y40.3 Macrolides	0.664	0.335
S63.3 Traumatic rupture of ligament of wrist and carpus	0.664	0.336
N11.8 Other chronic tubulo-interstitial nephritis	0.664	0.336
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.664	0.336
Q38 Other congenital malformations of tongue, mouth and pharynx	0.664	0.336
Y57.9 Drug or medicament, unspecified	0.664	0.336
N18.2 Chronic kidney disease, stage 2	0.663	0.337
Q53 Undescended testicle	0.663	0.337
M79.4 Hypertrophy of (infrapatellar) fat pad	0.662	0.338
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.662	0.338
M89.0 Algoneurodystrophy	0.662	0.338
S62.8 Fracture of other and unspecified parts of wrist and hand	0.662	0.338
H02.7 Other degenerative disorders of eyelid and periocular area	0.661	0.339
N03.8 Other	0.661	0.339
N03.7 Diffuse crescentic glomerulonephritis	0.661	0.339
N03.6 Dense deposit disease	0.661	0.339
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.661	0.339
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.661	0.339
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.661	0.339
N03.2 Diffuse membranous glomerulonephritis	0.661	0.339
N03.1 Focal and segmental glomerular lesions	0.661	0.339
N03.0 Minor glomerular abnormality	0.661	0.339
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.661	0.339
M06.32 Rheumatoid nodule (Upper arm)	0.660	0.340
S90-S99 Injuries to the ankle and foot	0.660	0.340
T84.2 Mechanical complication of internal fixation device of other bones	0.660	0.340
H18.9 Disorder of cornea, unspecified	0.659	0.341
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.659	0.341
N08.3 Glomerular disorders in diabetes mellitus	0.658	0.342
S50-S59 Injuries to the elbow and forearm	0.658	0.342
N28.9 Disorder of kidney and ureter, unspecified	0.658	0.342
Q64 Other congenital malformations of urinary system	0.656	0.344
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.656	0.344
M06.34 Rheumatoid nodule (Hand)	0.656	0.344
U89 Agent resistant to other and unspecified antibiotics	0.655	0.344
Q76 Congenital malformations of spine and bony thorax	0.654	0.346
N13.8 Other obstructive and reflux uropathy	0.654	0.346
Y49.5 Other antipsychotics and neuroleptics	0.653	0.347
M90 Osteopathies in diseases classified elsewhere	0.652	0.348
S68 Traumatic amputation of wrist and hand	0.652	0.348
N71.9 Inflammatory disease of uterus, unspecified	0.651	0.349
H49.1 Fourth [trochlear] nerve palsy	0.651	0.349
M05.8 Other seropositive rheumatoid arthritis	0.648	0.351
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.648	0.351
M05.2 Rheumatoid vasculitis	0.648	0.351
M05.1 Rheumatoid lung disease	0.648	0.351
M05.0 Felty's syndrome	0.648	0.351
M79.19 Myalgia (Site unspecified)	0.648	0.352
H52 Disorders of refraction and accommodation	0.647	0.353
H40-H42 Glaucoma	0.647	0.353
H49.2 Sixth [abducent] nerve palsy	0.645	0.355
H47 Other disorders of optic [2nd] nerve and visual pathways	0.645	0.355
S69 Other and unspecified injuries of wrist and hand	0.643	0.357
M73 Soft tissue disorders in diseases classified elsewhere	0.643	0.357
M79.16 Myalgia (Lower leg)	0.643	0.357
T86 Failure and rejection of transplanted organs and tissues	0.643	0.357
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.639	0.361
M79.67 Pain in limb (Ankle and foot)	0.637	0.363
H54.6 Unqualified visual loss, one eye	0.637	0.363
H54.5 Low vision, one eye	0.637	0.363
H54.3 Unqualified visual loss, both eyes	0.637	0.363
H54.2 Low vision, both eyes	0.637	0.363
H54.1 Blindness, one eye, low vision, other eye	0.637	0.363
M75.9 Shoulder lesion, unspecified	0.637	0.363
N76.4 Abscess of vulva	0.636	0.364
M79.9 Soft tissue disorder, unspecified	0.636	0.364
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.635	0.365
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.634	0.366
M79.10 Myalgia (Multiple sites)	0.634	0.366
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.633	0.367
Q78 Other osteochondrodysplasias	0.633	0.367
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.633	0.367
Q75 Other congenital malformations of skull and face bones	0.633	0.367
Q74 Other congenital malformations of limb(s)	0.633	0.367
Q73 Reduction defects of unspecified limb	0.633	0.367
Q72 Reduction defects of lower limb	0.633	0.367
Q71 Reduction defects of upper limb	0.633	0.367
Q70 Syndactyly	0.633	0.367
Q69 Polydactyly	0.633	0.367
Q68 Other congenital musculoskeletal deformities	0.633	0.367
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.631	0.369
H15 Disorders of sclera	0.631	0.369
T78 Adverse effects, not elsewhere classified	0.631	0.369
M10 Gout	0.630	0.370
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.630	0.370
T82.1 Mechanical complication of cardiac electronic device	0.628	0.372
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.628	0.372
Y52 Agents primarily affecting the cardiovascular system	0.628	0.372
H00 Hordeolum and chalazion	0.628	0.372
M89.3 Hypertrophy of bone	0.627	0.373
Y51 Drugs primarily affecting the autonomic nervous system	0.626	0.374
Q65 Congenital deformities of hip	0.626	0.374
H46 Optic neuritis	0.625	0.375
W44 Foreign body entering into or through eye or natural orifice	0.624	0.376
Y44.9 Other and unspecified agents affecting blood constituents	0.623	0.377
Y44.7 Plasma substitutes	0.623	0.377
Y44.6 Natural blood and blood products	0.623	0.377
Y44.5 Thrombolytic drugs	0.623	0.377
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.623	0.377
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.623	0.377
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.623	0.377
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.623	0.377
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.623	0.377
Q54 Hypospadias	0.622	0.378
Y04 Assault by bodily force	0.620	0.380
Q61.2 Polycystic kidney, adult type	0.619	0.381
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.619	0.381
V48 Car occupant injured in noncollision transport accident	0.619	0.381
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.618	0.381
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.618	0.381
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.618	0.381
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.618	0.382
Y41.4 Anthelminthics	0.618	0.382
Y41.3 Other antiprotozoal drugs	0.618	0.382
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.618	0.382
Y41.1 Antimycobacterial drugs	0.618	0.382
Y41.0 Sulphonamides	0.618	0.382
Q56 Indeterminate sex and pseudohermaphroditism	0.618	0.382
Q55 Other congenital malformations of male genital organs	0.618	0.382
Q52 Other congenital malformations of female genitalia	0.618	0.382
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.618	0.382
T88.7 Unspecified adverse effect of drug or medicament	0.617	0.383
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.617	0.383
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.617	0.383
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.617	0.383
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.617	0.383
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.617	0.383
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.617	0.383
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.617	0.383
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.617	0.383
Chapter X Diseases of the respiratory system	0.616	0.384
H94 Other disorders of ear in diseases classified elsewhere	0.616	0.384
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.616	0.384
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.615	0.385
W22 Striking against or struck by other objects	0.615	0.385
Y48.2 Other and unspecified general anaesthetics	0.613	0.387
Y43.1 Antineoplastic antimetabolites	0.613	0.387
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.613	0.387
H18.2 Other corneal oedema	0.612	0.388
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.611	0.389
M70 Soft tissue disorders related to use, overuse and pressure	0.611	0.389
H21 Other disorders of iris and ciliary body	0.610	0.390
Y48.3 Local anaesthetics	0.610	0.390
H16 Keratitis	0.610	0.390
T80.2 Infections following infusion, transfusion and therapeutic injection	0.610	0.390
S22 Fracture of rib(s), sternum and thoracic spine	0.609	0.391
M66 Spontaneous rupture of synovium and tendon	0.609	0.391
N18.3 Chronic kidney disease, stage 3	0.608	0.392
N73.8 Other specified female pelvic inflammatory diseases	0.607	0.392
N73.5 Female pelvic peritonitis, unspecified	0.607	0.392
N73.4 Female chronic pelvic peritonitis	0.607	0.392
N73.3 Female acute pelvic peritonitis	0.607	0.392
N73.2 Unspecified parametritis and pelvic cellulitis	0.607	0.392
N73.1 Chronic parametritis and pelvic cellulitis	0.607	0.392
N73.0 Acute parametritis and pelvic cellulitis	0.607	0.392
M89.6 Osteopathy after poliomyelitis	0.607	0.392
M89.5 Osteolysis	0.607	0.392
M89.4 Other hypertrophic osteo-arthropathy	0.607	0.392
M89.2 Other disorders of bone development and growth	0.607	0.392
M89.1 Epiphyseal arrest	0.607	0.392
M79.11 Myalgia (Shoulder region)	0.607	0.393
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.605	0.394
M15-M19 Arthrosis	0.605	0.395
H93.9 Disorder of ear, unspecified	0.604	0.396
H93.8 Other specified disorders of ear	0.604	0.396
H93.3 Disorders of acoustic nerve	0.604	0.396
H93.2 Other abnormal auditory perceptions	0.604	0.396
H93.0 Degenerative and vascular disorders of ear	0.604	0.396
Q63 Other congenital malformations of kidney	0.604	0.396
U89.8 Agent resistant to other single specified antibiotic	0.602	0.398
W06 Fall involving bed	0.602	0.398
Q45 Other congenital malformations of digestive system	0.601	0.398
Q42 Congenital absence, atresia and stenosis of large intestine	0.601	0.398
Q41 Congenital absence, atresia and stenosis of small intestine	0.601	0.398
Q40 Other congenital malformations of upper alimentary tract	0.601	0.398
Q39 Congenital malformations of oesophagus	0.601	0.398
M11 Other crystal arthropathies	0.601	0.399
Q12.0 Congenital cataract	0.601	0.399
V99 Unspecified transport accident	0.601	0.399
H17 Corneal scars and opacities	0.601	0.399
H53.9 Visual disturbance, unspecified	0.600	0.399
N76.6 Ulceration of vulva	0.600	0.399
N76.5 Ulceration of vagina	0.600	0.399
N76.3 Subacute and chronic vulvitis	0.600	0.399
H18.5 Hereditary corneal dystrophies	0.600	0.400
Q82 Other congenital malformations of skin	0.600	0.400
Y57.8 Other drugs and medicaments	0.600	0.400
T21 Burn and corrosion of trunk	0.600	0.400
S62.7 Multiple fractures of fingers	0.600	0.400
M07 Psoriatic and enteropathic arthropathies	0.599	0.400

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations